BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0018.0069.p (265 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J1Y9.1 D8J1Y9_HERSS Tryptophan synthase alpha chain EC=4.2.1.20 535 e-150 D7F7K0.1 D7F7K0_9BURK Tryptophan synthase alpha chain EC=4.2.1.20 436 e-120 A6T006.1 TRPA_JANMA Tryptophan synthase alpha chain EC=4.2.1.20 410 e-113 A4G4G3.1 TRPA_HERAR Tryptophan synthase alpha chain EC=4.2.1.20 400 e-110 F1VXH8.1 F1VXH8_9BURK Tryptophan synthase alpha chain 392 e-107 D8P1R0.1 D8P1R0_RALSO Tryptophan synthase alpha chain 5 EC=4.2.1.20 370 e-100 Q1LKI4.1 TRPA_RALME Tryptophan synthase alpha chain EC=4.2.1.20 369 e-100 D8NAR4.1 D8NAR4_RALSO Tryptophan synthase alpha chain 3 EC=4.2.1.20 368 e-100 B5SJ31.1 B5SJ31_RALSO Tryptophan synthase alpha chain EC=4.2.1.20 367 e-100 A3RVS0.1 A3RVS0_RALSO Tryptophan synthase alpha chain 1 EC=4.2.1.20 367 e-100 >D8J1Y9.1 D8J1Y9_HERSS Tryptophan synthase alpha chain EC=4.2.1.20 Length = 265 Score = 535 bits (1378), Expect = e-150, Method: Compositional matrix adjust. Identities = 264/265 (99%), Positives = 265/265 (100%) Query: 1 MSRIQTTFSQLAEQKRKALITFITAGDPAPELTVPLLHALVAGGVDILELGVPFSDPMAE 60 MSRIQTTFSQLAEQKRKALITFITAGDPAPELTVPLLHALVAGGVDILELGVPFSDPMAE Sbjct: 1 MSRIQTTFSQLAEQKRKALITFITAGDPAPELTVPLLHALVAGGVDILELGVPFSDPMAE 60 Query: 61 GPVIQRACERALKFGISTHDVLGYVREFRKTNTHTPIVLMGYANPIERFGVDAFIAAASE 120 GPVIQRACERALKFGISTHDVLGYVREFRKTNTHTPIVLMGYANPIERFGVDAFIAAASE Sbjct: 61 GPVIQRACERALKFGISTHDVLGYVREFRKTNTHTPIVLMGYANPIERFGVDAFIAAASE 120 Query: 121 AGVDGTIVVDYPPEECEEFAQKMQAKGMDPIFLLAPTSSEERIRQVAAVSSGFCYYVSLK 180 AGVDGTIVVDYPPEECEEFAQKMQAKGMDPIFLLAPTSS+ERIRQVAAVSSGFCYYVSLK Sbjct: 121 AGVDGTIVVDYPPEECEEFAQKMQAKGMDPIFLLAPTSSQERIRQVAAVSSGFCYYVSLK 180 Query: 181 GVTGAGHIDTAEVAERIAAIRQHVKLPIAVGFGIRDGATARTVGSVADAVVIGSRIIAEL 240 GVTGAGHIDTAEVAERIAAIRQHVKLPIAVGFGIRDGATARTVGSVADAVVIGSRIIAEL Sbjct: 181 GVTGAGHIDTAEVAERIAAIRQHVKLPIAVGFGIRDGATARTVGSVADAVVIGSRIIAEL 240 Query: 241 ENTPQDQACDAVQAFVTDIRQALDA 265 ENTPQDQACDAVQAFVTDIRQALDA Sbjct: 241 ENTPQDQACDAVQAFVTDIRQALDA 265 >D7F7K0.1 D7F7K0_9BURK Tryptophan synthase alpha chain EC=4.2.1.20 Length = 265 Score = 436 bits (1122), Expect = e-120, Method: Compositional matrix adjust. Identities = 208/264 (78%), Positives = 233/264 (88%) Query: 1 MSRIQTTFSQLAEQKRKALITFITAGDPAPELTVPLLHALVAGGVDILELGVPFSDPMAE 60 MSRIQTT + LA +K LI FITAGDPAPELTVPL+HALV GG DILELGVPFSDPMAE Sbjct: 1 MSRIQTTLAALAASNKKGLIPFITAGDPAPELTVPLMHALVRGGADILELGVPFSDPMAE 60 Query: 61 GPVIQRACERALKFGISTHDVLGYVREFRKTNTHTPIVLMGYANPIERFGVDAFIAAASE 120 GPVIQRACERALKFG+S HDVLGYVREFR+TN+ TP+VLMGYANP+ER G+DAFIAAA E Sbjct: 61 GPVIQRACERALKFGVSLHDVLGYVREFRQTNSRTPVVLMGYANPLERMGIDAFIAAAKE 120 Query: 121 AGVDGTIVVDYPPEECEEFAQKMQAKGMDPIFLLAPTSSEERIRQVAAVSSGFCYYVSLK 180 AGVDG+IVVDYPPEECEEFA KMQA GMDPIFLLAPTS+EERI+QVA V GF YYVSLK Sbjct: 121 AGVDGSIVVDYPPEECEEFAAKMQANGMDPIFLLAPTSTEERIKQVAKVGGGFTYYVSLK 180 Query: 181 GVTGAGHIDTAEVAERIAAIRQHVKLPIAVGFGIRDGATARTVGSVADAVVIGSRIIAEL 240 GVTGA +IDTAEVA R+AAIR+HVKLPI VGFGIRD ATA+ V V+DA+VIGSRII EL Sbjct: 181 GVTGAANIDTAEVAARVAAIRKHVKLPIGVGFGIRDAATAKAVAQVSDAIVIGSRIIQEL 240 Query: 241 ENTPQDQACDAVQAFVTDIRQALD 264 ENTP +A +AV++F++ IR+ALD Sbjct: 241 ENTPPGKAVEAVESFLSGIRKALD 264 >A6T006.1 TRPA_JANMA Tryptophan synthase alpha chain EC=4.2.1.20 Length = 265 Score = 410 bits (1055), Expect = e-113, Method: Compositional matrix adjust. Identities = 198/264 (75%), Positives = 222/264 (84%) Query: 1 MSRIQTTFSQLAEQKRKALITFITAGDPAPELTVPLLHALVAGGVDILELGVPFSDPMAE 60 MSRIQ+T + LA + +K LI FITAGDPAPELTVPL+HALVAGG DILELGVPFSDPMAE Sbjct: 1 MSRIQSTLAALAAKNKKGLIPFITAGDPAPELTVPLMHALVAGGADILELGVPFSDPMAE 60 Query: 61 GPVIQRACERALKFGISTHDVLGYVREFRKTNTHTPIVLMGYANPIERFGVDAFIAAASE 120 GPVIQRACERAL G+S HDVLG+V EFRKTN TP+VLMGYANPIER G FI AA Sbjct: 61 GPVIQRACERALASGVSMHDVLGFVSEFRKTNNSTPVVLMGYANPIERMGQTKFILAAKA 120 Query: 121 AGVDGTIVVDYPPEECEEFAQKMQAKGMDPIFLLAPTSSEERIRQVAAVSSGFCYYVSLK 180 AGVDGTIVVDYPPEECEEFA ++ MDPIFLL+PTS+EERI+QVA SGF YYVSLK Sbjct: 121 AGVDGTIVVDYPPEECEEFAATLKENDMDPIFLLSPTSTEERIQQVAKFGSGFSYYVSLK 180 Query: 181 GVTGAGHIDTAEVAERIAAIRQHVKLPIAVGFGIRDGATARTVGSVADAVVIGSRIIAEL 240 GVTGA +IDT EVAERIAAIR++VKLPI VGFGIRD ATA+ V V+DAVVIGSRII EL Sbjct: 181 GVTGAANIDTKEVAERIAAIRKYVKLPIGVGFGIRDAATAKAVAQVSDAVVIGSRIIQEL 240 Query: 241 ENTPQDQACDAVQAFVTDIRQALD 264 EN+P++QA + VQ F+ IR+ALD Sbjct: 241 ENSPREQAVERVQTFIAGIRKALD 264 >A4G4G3.1 TRPA_HERAR Tryptophan synthase alpha chain EC=4.2.1.20 Length = 265 Score = 400 bits (1029), Expect = e-110, Method: Compositional matrix adjust. Identities = 197/264 (74%), Positives = 228/264 (86%) Query: 1 MSRIQTTFSQLAEQKRKALITFITAGDPAPELTVPLLHALVAGGVDILELGVPFSDPMAE 60 MSRIQ+TF+ LA + +K LI FITAGDPAP+LTVPL+HALVAGG DILELGVPFSDPMAE Sbjct: 1 MSRIQSTFAALAAKNKKGLIPFITAGDPAPDLTVPLMHALVAGGADILELGVPFSDPMAE 60 Query: 61 GPVIQRACERALKFGISTHDVLGYVREFRKTNTHTPIVLMGYANPIERFGVDAFIAAASE 120 GPVIQRACERALKF +S HDVLG+V EFRKT+T TP+VLMGYANPIER G AF+ AA Sbjct: 61 GPVIQRACERALKFNVSLHDVLGFVSEFRKTDTTTPVVLMGYANPIERMGQTAFVLAAKA 120 Query: 121 AGVDGTIVVDYPPEECEEFAQKMQAKGMDPIFLLAPTSSEERIRQVAAVSSGFCYYVSLK 180 AGVDGTIVVDYPPEECEEFA ++A MDPIFLL+PTS+EERI+QVA SGF YYVSLK Sbjct: 121 AGVDGTIVVDYPPEECEEFAATLKANDMDPIFLLSPTSTEERIQQVAKFGSGFSYYVSLK 180 Query: 181 GVTGAGHIDTAEVAERIAAIRQHVKLPIAVGFGIRDGATARTVGSVADAVVIGSRIIAEL 240 GVTG+ +IDT +VA+RI AIR+HVKLPI VGFGIRD ATA+ V +V+DAVVIGSRII EL Sbjct: 181 GVTGSANIDTQDVAQRIEAIRKHVKLPIGVGFGIRDAATAKAVATVSDAVVIGSRIIQEL 240 Query: 241 ENTPQDQACDAVQAFVTDIRQALD 264 ENTP+++A +A Q F++ IR+ALD Sbjct: 241 ENTPRERAVEAAQTFISGIRKALD 264 >F1VXH8.1 F1VXH8_9BURK Tryptophan synthase alpha chain Length = 260 Score = 392 bits (1008), Expect = e-107, Method: Compositional matrix adjust. Identities = 195/258 (75%), Positives = 218/258 (84%) Query: 8 FSQLAEQKRKALITFITAGDPAPELTVPLLHALVAGGVDILELGVPFSDPMAEGPVIQRA 67 + LA + LI FITAGDP+P+LTVPL+HA+VAGG +ILELGVPFSDPMAEGPVIQRA Sbjct: 1 MAALAASHKTGLIPFITAGDPSPQLTVPLMHAMVAGGANILELGVPFSDPMAEGPVIQRA 60 Query: 68 CERALKFGISTHDVLGYVREFRKTNTHTPIVLMGYANPIERFGVDAFIAAASEAGVDGTI 127 CERALK+G+ DVL +VREFR+T+ TP+VLMGYANPIER G FIAAA+ AGVDGTI Sbjct: 61 CERALKYGVGLRDVLEFVREFRETDATTPVVLMGYANPIERMGQQVFIAAAAAAGVDGTI 120 Query: 128 VVDYPPEECEEFAQKMQAKGMDPIFLLAPTSSEERIRQVAAVSSGFCYYVSLKGVTGAGH 187 VVDYPPEECEEFA MQA+G+DPIFLLAPTS+E RIRQVAA GFCYYVSLKGVTGAG+ Sbjct: 121 VVDYPPEECEEFAAGMQAEGLDPIFLLAPTSTEARIRQVAAAGRGFCYYVSLKGVTGAGN 180 Query: 188 IDTAEVAERIAAIRQHVKLPIAVGFGIRDGATARTVGSVADAVVIGSRIIAELENTPQDQ 247 ID A+V+ERIAAIRQHVKLPIAVGFGIRDGATAR + SVADAVVIGSRII ELE TP D+ Sbjct: 181 IDIADVSERIAAIRQHVKLPIAVGFGIRDGATARAIASVADAVVIGSRIIQELETTPHDK 240 Query: 248 ACDAVQAFVTDIRQALDA 265 A + FV IR ALDA Sbjct: 241 AVETAHNFVAGIRAALDA 258 >D8P1R0.1 D8P1R0_RALSO Tryptophan synthase alpha chain 5 EC=4.2.1.20 Length = 265 Score = 370 bits (950), Expect = e-100, Method: Compositional matrix adjust. Identities = 182/265 (68%), Positives = 208/265 (78%) Query: 1 MSRIQTTFSQLAEQKRKALITFITAGDPAPELTVPLLHALVAGGVDILELGVPFSDPMAE 60 MSRI TFSQL+ Q RK LI FITAGDP PELTV L+HALV GG +++ELGVPFSDPMA+ Sbjct: 1 MSRIAHTFSQLSAQGRKGLIPFITAGDPYPELTVDLMHALVKGGANVIELGVPFSDPMAD 60 Query: 61 GPVIQRACERALKFGISTHDVLGYVREFRKTNTHTPIVLMGYANPIERFGVDAFIAAASE 120 GPVIQRA ERAL + VL YVR FR T+ TP+VLMGYANPIER G+DAF AASE Sbjct: 61 GPVIQRASERALAKKVGLRTVLDYVRAFRATDKTTPVVLMGYANPIERMGIDAFAKAASE 120 Query: 121 AGVDGTIVVDYPPEECEEFAQKMQAKGMDPIFLLAPTSSEERIRQVAAVSSGFCYYVSLK 180 AGVDG +VVDYPPEECE FA+ MQA G+DPIFLLAPTS+E RI Q+A V+SG+ YYVSLK Sbjct: 121 AGVDGVLVVDYPPEECEAFAKTMQATGIDPIFLLAPTSTEARIAQIARVASGYIYYVSLK 180 Query: 181 GVTGAGHIDTAEVAERIAAIRQHVKLPIAVGFGIRDGATARTVGSVADAVVIGSRIIAEL 240 GVTGA +D VA RI IRQH +LP+ VGFGIRD ATAR +G VADAVVIGSRI+ L Sbjct: 181 GVTGAATLDLDSVAARIPQIRQHARLPVGVGFGIRDAATARAIGGVADAVVIGSRIVQLL 240 Query: 241 ENTPQDQACDAVQAFVTDIRQALDA 265 E P++QA + F+ DIRQALDA Sbjct: 241 EEAPREQAVQCLTDFIADIRQALDA 265 >Q1LKI4.1 TRPA_RALME Tryptophan synthase alpha chain EC=4.2.1.20 Length = 265 Score = 369 bits (947), Expect = e-100, Method: Compositional matrix adjust. Identities = 177/265 (66%), Positives = 211/265 (79%) Query: 1 MSRIQTTFSQLAEQKRKALITFITAGDPAPELTVPLLHALVAGGVDILELGVPFSDPMAE 60 MSRIQ TF+ LA Q++K LI FITAGDPAP LTV L+HALVAGG D++ELGVPFSDPMA+ Sbjct: 1 MSRIQKTFAALAAQQKKGLIPFITAGDPAPALTVDLMHALVAGGADVIELGVPFSDPMAD 60 Query: 61 GPVIQRACERALKFGISTHDVLGYVREFRKTNTHTPIVLMGYANPIERFGVDAFIAAASE 120 GPVIQRA ERAL G+S VL +V EFRKTN TP+VLMGYANPIER G + F AAS Sbjct: 61 GPVIQRASERALAQGVSLTQVLAWVTEFRKTNATTPVVLMGYANPIERMGEETFAKAASA 120 Query: 121 AGVDGTIVVDYPPEECEEFAQKMQAKGMDPIFLLAPTSSEERIRQVAAVSSGFCYYVSLK 180 AGVDG +VVDYPPEECE FA M+A MDPIFLLAPTS+++RI VA V+SG+ YYVSL Sbjct: 121 AGVDGVLVVDYPPEECESFAALMRANQMDPIFLLAPTSTDDRIAAVAKVASGYLYYVSLT 180 Query: 181 GVTGAGHIDTAEVAERIAAIRQHVKLPIAVGFGIRDGATARTVGSVADAVVIGSRIIAEL 240 GVTG+ +D VA R+ I+QH LP+ VGFGIRD TAR +GSVADAVVIGSR++ L Sbjct: 181 GVTGSATLDLESVAARLPLIKQHANLPVGVGFGIRDAQTARAIGSVADAVVIGSRLVQLL 240 Query: 241 ENTPQDQACDAVQAFVTDIRQALDA 265 E+ P+++A D+++AF+ DIRQALDA Sbjct: 241 EDAPREKAVDSLRAFIADIRQALDA 265 >D8NAR4.1 D8NAR4_RALSO Tryptophan synthase alpha chain 3 EC=4.2.1.20 Length = 265 Score = 368 bits (944), Expect = e-100, Method: Compositional matrix adjust. Identities = 181/265 (68%), Positives = 207/265 (78%) Query: 1 MSRIQTTFSQLAEQKRKALITFITAGDPAPELTVPLLHALVAGGVDILELGVPFSDPMAE 60 MSRI TFSQL+ Q RK LI FITAGDP PELTV L+HALV GG +++ELGVPFSDPMA+ Sbjct: 1 MSRIAQTFSQLSAQGRKGLIPFITAGDPYPELTVDLMHALVKGGANVIELGVPFSDPMAD 60 Query: 61 GPVIQRACERALKFGISTHDVLGYVREFRKTNTHTPIVLMGYANPIERFGVDAFIAAASE 120 GPVIQRA ERAL I VL YVR FR T+ TP+VLMGYANPIER G+DAF AASE Sbjct: 61 GPVIQRASERALAKKIGLRTVLDYVRAFRATDKTTPVVLMGYANPIERMGIDAFAKAASE 120 Query: 121 AGVDGTIVVDYPPEECEEFAQKMQAKGMDPIFLLAPTSSEERIRQVAAVSSGFCYYVSLK 180 AGVDG +VVDYPPEECE FA+ MQA G+DPIFLLAPTS+E R+ Q+A V+SG+ YYVSLK Sbjct: 121 AGVDGVLVVDYPPEECEAFAKTMQAAGIDPIFLLAPTSTEARMAQIARVASGYIYYVSLK 180 Query: 181 GVTGAGHIDTAEVAERIAAIRQHVKLPIAVGFGIRDGATARTVGSVADAVVIGSRIIAEL 240 GVTGA +D VA RI IRQH +LP+ VGFGIRD ATAR +G VADAVVIGSRI+ L Sbjct: 181 GVTGAATLDLDSVAARIPQIRQHARLPVGVGFGIRDAATARAIGGVADAVVIGSRIVQLL 240 Query: 241 ENTPQDQACDAVQAFVTDIRQALDA 265 E ++QA + F+ DIRQALDA Sbjct: 241 EEASREQAVQCLTDFIADIRQALDA 265 >B5SJ31.1 B5SJ31_RALSO Tryptophan synthase alpha chain EC=4.2.1.20 Length = 265 Score = 367 bits (943), Expect = e-100, Method: Compositional matrix adjust. Identities = 180/265 (67%), Positives = 208/265 (78%) Query: 1 MSRIQTTFSQLAEQKRKALITFITAGDPAPELTVPLLHALVAGGVDILELGVPFSDPMAE 60 MSRI TFSQL+ Q RK LI F+TAGDP PELTV L+HALV GG +++ELGVPFSDPMA+ Sbjct: 1 MSRIAQTFSQLSAQGRKGLIPFVTAGDPYPELTVDLMHALVKGGANVIELGVPFSDPMAD 60 Query: 61 GPVIQRACERALKFGISTHDVLGYVREFRKTNTHTPIVLMGYANPIERFGVDAFIAAASE 120 GPVIQRA ERAL I VL YVR FR T+ TP+VLMGYANPIER G+DAF AASE Sbjct: 61 GPVIQRASERALAKKIGLRTVLDYVRAFRATDKTTPVVLMGYANPIERMGIDAFAKAASE 120 Query: 121 AGVDGTIVVDYPPEECEEFAQKMQAKGMDPIFLLAPTSSEERIRQVAAVSSGFCYYVSLK 180 AGVDG +VVDYPPEECE FA+ M+A G+DPIFLLAPTS+E RI Q+A V+SG+ YYVSLK Sbjct: 121 AGVDGVLVVDYPPEECEAFAKTMRATGIDPIFLLAPTSTEARIAQIARVASGYLYYVSLK 180 Query: 181 GVTGAGHIDTAEVAERIAAIRQHVKLPIAVGFGIRDGATARTVGSVADAVVIGSRIIAEL 240 GVTGA +D VA RI IRQH +LP+ VGFGIRD ATAR +G VADAVVIGSRI+ L Sbjct: 181 GVTGAATLDLDSVAARIPQIRQHARLPVGVGFGIRDAATARAIGGVADAVVIGSRIVQLL 240 Query: 241 ENTPQDQACDAVQAFVTDIRQALDA 265 E P++QA + F+ DIR+ALDA Sbjct: 241 EEAPREQAVQCLTDFIADIRRALDA 265 >A3RVS0.1 A3RVS0_RALSO Tryptophan synthase alpha chain 1 EC=4.2.1.20 Length = 265 Score = 367 bits (943), Expect = e-100, Method: Compositional matrix adjust. Identities = 180/265 (67%), Positives = 208/265 (78%) Query: 1 MSRIQTTFSQLAEQKRKALITFITAGDPAPELTVPLLHALVAGGVDILELGVPFSDPMAE 60 MSRI TFSQL+ Q RK LI F+TAGDP PELTV L+HALV GG +++ELGVPFSDPMA+ Sbjct: 1 MSRIAQTFSQLSAQGRKGLIPFVTAGDPYPELTVDLMHALVKGGANVIELGVPFSDPMAD 60 Query: 61 GPVIQRACERALKFGISTHDVLGYVREFRKTNTHTPIVLMGYANPIERFGVDAFIAAASE 120 GPVIQRA ERAL I VL YVR FR T+ TP+VLMGYANPIER G+DAF AASE Sbjct: 61 GPVIQRASERALAKKIGLRTVLDYVRAFRATDKTTPVVLMGYANPIERMGIDAFAKAASE 120 Query: 121 AGVDGTIVVDYPPEECEEFAQKMQAKGMDPIFLLAPTSSEERIRQVAAVSSGFCYYVSLK 180 AGVDG +VVDYPPEECE FA+ M+A G+DPIFLLAPTS+E RI Q+A V+SG+ YYVSLK Sbjct: 121 AGVDGVLVVDYPPEECEAFAKTMRATGIDPIFLLAPTSTEARIAQIARVASGYLYYVSLK 180 Query: 181 GVTGAGHIDTAEVAERIAAIRQHVKLPIAVGFGIRDGATARTVGSVADAVVIGSRIIAEL 240 GVTGA +D VA RI IRQH +LP+ VGFGIRD ATAR +G VADAVVIGSRI+ L Sbjct: 181 GVTGAATLDLDSVAARIPQIRQHARLPVGVGFGIRDAATARAIGGVADAVVIGSRIVQLL 240 Query: 241 ENTPQDQACDAVQAFVTDIRQALDA 265 E P++QA + F+ DIR+ALDA Sbjct: 241 EEAPREQAVQCLTDFIADIRRALDA 265