BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0017.0098.p (271 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J0X1.1 D8J0X1_HERSS Cyclase protein 562 e-158 B7X2X0.1 B7X2X0_COMTE Cyclase family protein 507 e-142 B9B7K8.1 B9B7K8_9BURK Polyketide cyclase 491 e-137 B5WKU7.1 B5WKU7_9BURK Cyclase family protein 489 e-136 B1YYP0.1 B1YYP0_BURA4 Cyclase family protein 488 e-136 A4JED9.1 A4JED9_BURVG Cyclase family protein 487 e-136 B9C5M7.1 B9C5M7_9BURK Polyketide cyclase 487 e-136 B9BLM3.1 B9BLM3_9BURK Polyketide cyclase 487 e-136 D3P4T9.1 D3P4T9_AZOS1 Protein 478 e-133 C5CW66.1 C5CW66_VARPS Cyclase family protein 413 e-113 >D8J0X1.1 D8J0X1_HERSS Cyclase protein Length = 271 Score = 562 bits (1449), Expect = e-158, Method: Compositional matrix adjust. Identities = 270/271 (99%), Positives = 271/271 (100%) Query: 1 MTASLQARRRHRFVDLSIYLENDVLSDPPPLAPKITYQQHADTLPEFMAMLPGTQPEDYP 60 MTASLQARRRHRFVDLSIYLENDVLSDPPPLAPKITYQQHADTLPEFMAMLPGT+PEDYP Sbjct: 1 MTASLQARRRHRFVDLSIYLENDVLSDPPPLAPKITYQQHADTLPEFMAMLPGTRPEDYP 60 Query: 61 DGEAAAAEWVTLTTHNGTHLDAPWHFHSTQDAKNGGARPSITIDEVPLEWCFQPGVKLDF 120 DGEAAAAEWVTLTTHNGTHLDAPWHFHSTQDAKNGGARPSITIDEVPLEWCFQPGVKLDF Sbjct: 61 DGEAAAAEWVTLTTHNGTHLDAPWHFHSTQDAKNGGARPSITIDEVPLEWCFQPGVKLDF 120 Query: 121 RHFPDGYVATAADVEAELKRIGHVLEPLDIVVVNTRAGSRYGHRDYLGAGCGMGYEATMY 180 RHFPDGYVATAADVEAELKRIGHVLEPLDIVVVNTRAGSRYGHRDYLGAGCGMGYEATMY Sbjct: 121 RHFPDGYVATAADVEAELKRIGHVLEPLDIVVVNTRAGSRYGHRDYLGAGCGMGYEATMY 180 Query: 181 LLERGVRLTGTDAWSWDAPFSYTAQRVAETGNKALIWEGHKAGRDIGYCHLEKLHNLEAL 240 LLERGVRLTGTDAWSWDAPFSYTAQRVAETGNKALIWEGHKAGRDIGYCHLEKLHNLEAL Sbjct: 181 LLERGVRLTGTDAWSWDAPFSYTAQRVAETGNKALIWEGHKAGRDIGYCHLEKLHNLEAL 240 Query: 241 PAHGFMISCFPHKIRGASAGWTRAVAIFDAA 271 PAHGFMISCFPHKIRGASAGWTRAVAIFDAA Sbjct: 241 PAHGFMISCFPHKIRGASAGWTRAVAIFDAA 271 >B7X2X0.1 B7X2X0_COMTE Cyclase family protein Length = 270 Score = 507 bits (1306), Expect = e-142, Method: Compositional matrix adjust. Identities = 240/262 (91%), Positives = 252/262 (96%) Query: 8 RRRHRFVDLSIYLENDVLSDPPPLAPKITYQQHADTLPEFMAMLPGTQPEDYPDGEAAAA 67 + R RFVDLSIYLENDVLSDPPPLAPKITYQ+H DTLPEFMAM+PGT PEDYPDGEAAAA Sbjct: 3 KPRRRFVDLSIYLENDVLSDPPPLAPKITYQKHQDTLPEFMAMIPGTTPEDYPDGEAAAA 62 Query: 68 EWVTLTTHNGTHLDAPWHFHSTQDAKNGGARPSITIDEVPLEWCFQPGVKLDFRHFPDGY 127 EWVTLTTH+GTHLDAPWHFHSTQDAK GG+RPSITIDEVPLEWCFQPGVKLDFR+FPDGY Sbjct: 63 EWVTLTTHSGTHLDAPWHFHSTQDAKLGGSRPSITIDEVPLEWCFQPGVKLDFRYFPDGY 122 Query: 128 VATAADVEAELKRIGHVLEPLDIVVVNTRAGSRYGHRDYLGAGCGMGYEATMYLLERGVR 187 VATAADVEAELKRIGH ++PLDIVVVNTRAGSRYG+ DYLGAGCGMGYEATMYLLERGVR Sbjct: 123 VATAADVEAELKRIGHEIQPLDIVVVNTRAGSRYGNADYLGAGCGMGYEATMYLLERGVR 182 Query: 188 LTGTDAWSWDAPFSYTAQRVAETGNKALIWEGHKAGRDIGYCHLEKLHNLEALPAHGFMI 247 LTGTDAWSWDAPFSYTA +VAETGNKALIWEGHKAGRDIGYCHLEKLHNLEALP GF+I Sbjct: 183 LTGTDAWSWDAPFSYTAAKVAETGNKALIWEGHKAGRDIGYCHLEKLHNLEALPPTGFLI 242 Query: 248 SCFPHKIRGASAGWTRAVAIFD 269 SCFPHKIRGASAGWTRAVAIF+ Sbjct: 243 SCFPHKIRGASAGWTRAVAIFE 264 >B9B7K8.1 B9B7K8_9BURK Polyketide cyclase Length = 269 Score = 491 bits (1264), Expect = e-137, Method: Compositional matrix adjust. Identities = 231/258 (89%), Positives = 244/258 (94%) Query: 12 RFVDLSIYLENDVLSDPPPLAPKITYQQHADTLPEFMAMLPGTQPEDYPDGEAAAAEWVT 71 RFVDLSIYLENDVLSDPPPLAP+I YQ+H DTLPEFMAMLPGT+PEDYPDGEAAAAEWVT Sbjct: 6 RFVDLSIYLENDVLSDPPPLAPRIRYQKHGDTLPEFMAMLPGTKPEDYPDGEAAAAEWVT 65 Query: 72 LTTHNGTHLDAPWHFHSTQDAKNGGARPSITIDEVPLEWCFQPGVKLDFRHFPDGYVATA 131 LTTH+GTHLDAPWHFHST DA G ARPSITIDEVPLEWCFQPGVKLDFRHFPDGYVATA Sbjct: 66 LTTHSGTHLDAPWHFHSTMDASLGEARPSITIDEVPLEWCFQPGVKLDFRHFPDGYVATA 125 Query: 132 ADVEAELKRIGHVLEPLDIVVVNTRAGSRYGHRDYLGAGCGMGYEATMYLLERGVRLTGT 191 ADVEAEL RIGH L+PLDIVV NTRAG+RYGH DY+ AGCGMGYEATMYLLERGVRLTGT Sbjct: 126 ADVEAELARIGHELQPLDIVVANTRAGARYGHADYVNAGCGMGYEATMYLLERGVRLTGT 185 Query: 192 DAWSWDAPFSYTAQRVAETGNKALIWEGHKAGRDIGYCHLEKLHNLEALPAHGFMISCFP 251 DAWSWDAPF YTA+++AETG+ +LIWEGHKAGRDIGYCHLEKLHNLEALP+HGF ISCFP Sbjct: 186 DAWSWDAPFCYTAKKIAETGDTSLIWEGHKAGRDIGYCHLEKLHNLEALPSHGFFISCFP 245 Query: 252 HKIRGASAGWTRAVAIFD 269 HKIRGASAGWTRAVAIFD Sbjct: 246 HKIRGASAGWTRAVAIFD 263 >B5WKU7.1 B5WKU7_9BURK Cyclase family protein Length = 269 Score = 489 bits (1259), Expect = e-136, Method: Compositional matrix adjust. Identities = 230/259 (88%), Positives = 246/259 (94%) Query: 12 RFVDLSIYLENDVLSDPPPLAPKITYQQHADTLPEFMAMLPGTQPEDYPDGEAAAAEWVT 71 RFVDLSIYLEN+VLSDPPPLAPKITYQ+H+DTLPEFMAMLPGT+PEDYPDGEAAAAEWVT Sbjct: 6 RFVDLSIYLENEVLSDPPPLAPKITYQKHSDTLPEFMAMLPGTKPEDYPDGEAAAAEWVT 65 Query: 72 LTTHNGTHLDAPWHFHSTQDAKNGGARPSITIDEVPLEWCFQPGVKLDFRHFPDGYVATA 131 LTTH+GTHLDAPWHFHST DA G ARPSITID+VPLEWCFQ GVKLDFRHFPDGYV TA Sbjct: 66 LTTHSGTHLDAPWHFHSTMDAGLGEARPSITIDQVPLEWCFQAGVKLDFRHFPDGYVVTA 125 Query: 132 ADVEAELKRIGHVLEPLDIVVVNTRAGSRYGHRDYLGAGCGMGYEATMYLLERGVRLTGT 191 ADVEAEL RIGHVL+PLDIVVVNT AG+RYGH DY+ +GCGMGYEATMYLLERGVRLTGT Sbjct: 126 ADVEAELARIGHVLQPLDIVVVNTHAGARYGHHDYVNSGCGMGYEATMYLLERGVRLTGT 185 Query: 192 DAWSWDAPFSYTAQRVAETGNKALIWEGHKAGRDIGYCHLEKLHNLEALPAHGFMISCFP 251 DAWSWDAPFSYTA+++AETG+ +LIWEGHKAGRDIGYCHLEKLHNLEALP GFMISCFP Sbjct: 186 DAWSWDAPFSYTAKKIAETGDTSLIWEGHKAGRDIGYCHLEKLHNLEALPPTGFMISCFP 245 Query: 252 HKIRGASAGWTRAVAIFDA 270 HKIRGASAGWTRAVAIF+A Sbjct: 246 HKIRGASAGWTRAVAIFEA 264 >B1YYP0.1 B1YYP0_BURA4 Cyclase family protein Length = 271 Score = 488 bits (1257), Expect = e-136, Method: Compositional matrix adjust. Identities = 230/258 (89%), Positives = 244/258 (94%) Query: 12 RFVDLSIYLENDVLSDPPPLAPKITYQQHADTLPEFMAMLPGTQPEDYPDGEAAAAEWVT 71 RFVDLSIYLENDVLSDPPPLAP+I+YQ+H DTLPEFMAMLPGT+PEDYPDGEAAAAEWVT Sbjct: 6 RFVDLSIYLENDVLSDPPPLAPRISYQKHGDTLPEFMAMLPGTKPEDYPDGEAAAAEWVT 65 Query: 72 LTTHNGTHLDAPWHFHSTQDAKNGGARPSITIDEVPLEWCFQPGVKLDFRHFPDGYVATA 131 LTTH+GTHLDAPWHFHST DA G ARPSITID+VPLEWCFQPGVKLDFRHFPDGYVATA Sbjct: 66 LTTHSGTHLDAPWHFHSTMDASLGEARPSITIDQVPLEWCFQPGVKLDFRHFPDGYVATA 125 Query: 132 ADVEAELKRIGHVLEPLDIVVVNTRAGSRYGHRDYLGAGCGMGYEATMYLLERGVRLTGT 191 ADVEAEL RIGH L+PLDIVVVNTRAGSRYGH DY+ AGCGMGYEATMYLLERG+RLTGT Sbjct: 126 ADVEAELARIGHELQPLDIVVVNTRAGSRYGHDDYVNAGCGMGYEATMYLLERGMRLTGT 185 Query: 192 DAWSWDAPFSYTAQRVAETGNKALIWEGHKAGRDIGYCHLEKLHNLEALPAHGFMISCFP 251 DAWSWDAPFSYTA+++AETG+ +LIWEGHKAGRDIGYCHLEKLHNL ALP GF ISCFP Sbjct: 186 DAWSWDAPFSYTAKKIAETGDTSLIWEGHKAGRDIGYCHLEKLHNLTALPPTGFTISCFP 245 Query: 252 HKIRGASAGWTRAVAIFD 269 HKIRGASAGWTRAVAIFD Sbjct: 246 HKIRGASAGWTRAVAIFD 263 >A4JED9.1 A4JED9_BURVG Cyclase family protein Length = 271 Score = 487 bits (1254), Expect = e-136, Method: Compositional matrix adjust. Identities = 230/258 (89%), Positives = 244/258 (94%) Query: 12 RFVDLSIYLENDVLSDPPPLAPKITYQQHADTLPEFMAMLPGTQPEDYPDGEAAAAEWVT 71 RFVDLSIYLENDVLSDPPPLAPKITYQ+HADTLPEFMAMLPGT+ +DYPDGEAAAAEWVT Sbjct: 6 RFVDLSIYLENDVLSDPPPLAPKITYQKHADTLPEFMAMLPGTKADDYPDGEAAAAEWVT 65 Query: 72 LTTHNGTHLDAPWHFHSTQDAKNGGARPSITIDEVPLEWCFQPGVKLDFRHFPDGYVATA 131 LTTH+GTHLDAPWHFHST DA+ G ARPSITIDEVPLEWCFQPGVKLDFRHFPDGYVA+A Sbjct: 66 LTTHSGTHLDAPWHFHSTMDARLGEARPSITIDEVPLEWCFQPGVKLDFRHFPDGYVASA 125 Query: 132 ADVEAELKRIGHVLEPLDIVVVNTRAGSRYGHRDYLGAGCGMGYEATMYLLERGVRLTGT 191 ADVEAEL RIGH L+PLDIVVVNTRAGSRYGH DY+ AGCGMGYEATMYLLERGVRLTGT Sbjct: 126 ADVEAELARIGHALQPLDIVVVNTRAGSRYGHGDYVNAGCGMGYEATMYLLERGVRLTGT 185 Query: 192 DAWSWDAPFSYTAQRVAETGNKALIWEGHKAGRDIGYCHLEKLHNLEALPAHGFMISCFP 251 DAWSWDAPFSYTA ++A+TG+ +LIWEGHKAGRDIGYCHLEKLHNLEALP GF ISCFP Sbjct: 186 DAWSWDAPFSYTATKIAQTGDTSLIWEGHKAGRDIGYCHLEKLHNLEALPPAGFTISCFP 245 Query: 252 HKIRGASAGWTRAVAIFD 269 HKIRGASAGWTRAVAI + Sbjct: 246 HKIRGASAGWTRAVAILE 263 >B9C5M7.1 B9C5M7_9BURK Polyketide cyclase Length = 271 Score = 487 bits (1254), Expect = e-136, Method: Compositional matrix adjust. Identities = 231/258 (89%), Positives = 242/258 (93%) Query: 12 RFVDLSIYLENDVLSDPPPLAPKITYQQHADTLPEFMAMLPGTQPEDYPDGEAAAAEWVT 71 RFVDLSIYLENDVLSDPPPLAPKI YQ+H DTLPEFMAMLPGT+PEDYPDGEAAAAEWVT Sbjct: 6 RFVDLSIYLENDVLSDPPPLAPKIRYQKHGDTLPEFMAMLPGTKPEDYPDGEAAAAEWVT 65 Query: 72 LTTHNGTHLDAPWHFHSTQDAKNGGARPSITIDEVPLEWCFQPGVKLDFRHFPDGYVATA 131 LTTH+GTHLDAPWHFHST DA G ARPSITID+VPLEWCFQPGVKLDFRHFPDGYVATA Sbjct: 66 LTTHSGTHLDAPWHFHSTMDASLGEARPSITIDQVPLEWCFQPGVKLDFRHFPDGYVATA 125 Query: 132 ADVEAELKRIGHVLEPLDIVVVNTRAGSRYGHRDYLGAGCGMGYEATMYLLERGVRLTGT 191 ADVEAEL RIGH L+PLDIVVVNTRAGSRYGH DY+ AGCGMGYEATMYLLERGVRLTGT Sbjct: 126 ADVEAELARIGHELQPLDIVVVNTRAGSRYGHDDYVNAGCGMGYEATMYLLERGVRLTGT 185 Query: 192 DAWSWDAPFSYTAQRVAETGNKALIWEGHKAGRDIGYCHLEKLHNLEALPAHGFMISCFP 251 DAWSWDAPF YTA+++AETG+ +LIWEGHKAGRDIGYCHLEKLHNL ALP GF ISCFP Sbjct: 186 DAWSWDAPFCYTAKKIAETGDTSLIWEGHKAGRDIGYCHLEKLHNLTALPPTGFTISCFP 245 Query: 252 HKIRGASAGWTRAVAIFD 269 HKIRGASAGWTRAVAIFD Sbjct: 246 HKIRGASAGWTRAVAIFD 263 >B9BLM3.1 B9BLM3_9BURK Polyketide cyclase Length = 271 Score = 487 bits (1254), Expect = e-136, Method: Compositional matrix adjust. Identities = 231/258 (89%), Positives = 242/258 (93%) Query: 12 RFVDLSIYLENDVLSDPPPLAPKITYQQHADTLPEFMAMLPGTQPEDYPDGEAAAAEWVT 71 RFVDLSIYLENDVLSDPPPLAPKI YQ+H DTLPEFMAMLPGT+PEDYPDGEAAAAEWVT Sbjct: 6 RFVDLSIYLENDVLSDPPPLAPKIRYQKHGDTLPEFMAMLPGTKPEDYPDGEAAAAEWVT 65 Query: 72 LTTHNGTHLDAPWHFHSTQDAKNGGARPSITIDEVPLEWCFQPGVKLDFRHFPDGYVATA 131 LTTH+GTHLDAPWHFHST DA G ARPSITID+VPLEWCFQPGVKLDFRHFPDGYVATA Sbjct: 66 LTTHSGTHLDAPWHFHSTMDASLGEARPSITIDQVPLEWCFQPGVKLDFRHFPDGYVATA 125 Query: 132 ADVEAELKRIGHVLEPLDIVVVNTRAGSRYGHRDYLGAGCGMGYEATMYLLERGVRLTGT 191 ADVEAEL RIGH L+PLDIVVVNTRAGSRYGH DY+ AGCGMGYEATMYLLERGVRLTGT Sbjct: 126 ADVEAELARIGHELQPLDIVVVNTRAGSRYGHDDYVNAGCGMGYEATMYLLERGVRLTGT 185 Query: 192 DAWSWDAPFSYTAQRVAETGNKALIWEGHKAGRDIGYCHLEKLHNLEALPAHGFMISCFP 251 DAWSWDAPF YTA+++AETG+ +LIWEGHKAGRDIGYCHLEKLHNL ALP GF ISCFP Sbjct: 186 DAWSWDAPFCYTAKKIAETGDTSLIWEGHKAGRDIGYCHLEKLHNLTALPPTGFTISCFP 245 Query: 252 HKIRGASAGWTRAVAIFD 269 HKIRGASAGWTRAVAIFD Sbjct: 246 HKIRGASAGWTRAVAIFD 263 >D3P4T9.1 D3P4T9_AZOS1 Protein Length = 267 Score = 478 bits (1231), Expect = e-133, Method: Compositional matrix adjust. Identities = 226/265 (85%), Positives = 245/265 (92%), Gaps = 2/265 (0%) Query: 5 LQARRRHRFVDLSIYLENDVLSDPPPLAPKITYQQHADTLPEFMAMLPGTQPEDYPDGEA 64 L A+RR VDLSIYLENDVLSDPPPLAPKITYQ+HADT+PEF+ MLPG + E++PDGEA Sbjct: 3 LTAKRR--LVDLSIYLENDVLSDPPPLAPKITYQKHADTVPEFLQMLPGVRAENFPDGEA 60 Query: 65 AAAEWVTLTTHNGTHLDAPWHFHSTQDAKNGGARPSITIDEVPLEWCFQPGVKLDFRHFP 124 AAAEWVTLTTHNGTHLDAPWHFHST DAK G R SITIDEVPL+WC QPGVKLDFRHFP Sbjct: 61 AAAEWVTLTTHNGTHLDAPWHFHSTMDAKLGERRKSITIDEVPLDWCLQPGVKLDFRHFP 120 Query: 125 DGYVATAADVEAELKRIGHVLEPLDIVVVNTRAGSRYGHRDYLGAGCGMGYEATMYLLER 184 DGYVATAADVE EL RIGH L+PLDIV+VNTRAGS YG+ DYLGAGCGMGYEATM+LLER Sbjct: 121 DGYVATAADVERELDRIGHTLQPLDIVLVNTRAGSCYGNTDYLGAGCGMGYEATMFLLER 180 Query: 185 GVRLTGTDAWSWDAPFSYTAQRVAETGNKALIWEGHKAGRDIGYCHLEKLHNLEALPAHG 244 GVRLTGTDAWSWDAPFSYTAQ++AETG+ +LIWEGHKAGRDIGYCHLEKLHNLEALP HG Sbjct: 181 GVRLTGTDAWSWDAPFSYTAQKIAETGDTSLIWEGHKAGRDIGYCHLEKLHNLEALPGHG 240 Query: 245 FMISCFPHKIRGASAGWTRAVAIFD 269 F++SCFPHKIRGASAGWTRAVAIF+ Sbjct: 241 FLVSCFPHKIRGASAGWTRAVAIFE 265 >C5CW66.1 C5CW66_VARPS Cyclase family protein Length = 268 Score = 413 bits (1062), Expect = e-113, Method: Compositional matrix adjust. Identities = 197/260 (75%), Positives = 213/260 (81%) Query: 12 RFVDLSIYLENDVLSDPPPLAPKITYQQHADTLPEFMAMLPGTQPEDYPDGEAAAAEWVT 71 +FVDLSI+LENDVLSDPP APKI Y H T + PG + ED PDGE A E V Sbjct: 4 KFVDLSIFLENDVLSDPPAFAPKIQYFTHEQTYEQIEPFFPGLKKEDLPDGEGWAVELVQ 63 Query: 72 LTTHNGTHLDAPWHFHSTQDAKNGGARPSITIDEVPLEWCFQPGVKLDFRHFPDGYVATA 131 L+THNGTHLDAP+HFHST D G +P+I I EVPLEWCFQPGVKLDFRHF DGYV TA Sbjct: 64 LSTHNGTHLDAPYHFHSTMDKALGEKKPAIAIHEVPLEWCFQPGVKLDFRHFADGYVVTA 123 Query: 132 ADVEAELKRIGHVLEPLDIVVVNTRAGSRYGHRDYLGAGCGMGYEATMYLLERGVRLTGT 191 DVEAELKRIGH L PL+IVVVNTRAGSRYGH DY+ AG GMGYEATMYLLERGVRLTGT Sbjct: 124 GDVEAELKRIGHTLSPLEIVVVNTRAGSRYGHNDYVSAGAGMGYEATMYLLERGVRLTGT 183 Query: 192 DAWSWDAPFSYTAQRVAETGNKALIWEGHKAGRDIGYCHLEKLHNLEALPAHGFMISCFP 251 DAWSWDAPF +TA++ ET + +LIWEGHKAGRDIGYCH+EKLHNLEALP GF ISCFP Sbjct: 184 DAWSWDAPFVHTAKKYGETHDASLIWEGHKAGRDIGYCHIEKLHNLEALPPTGFFISCFP 243 Query: 252 HKIRGASAGWTRAVAIFDAA 271 HKIRGASAGWTRAVAIFD A Sbjct: 244 HKIRGASAGWTRAVAIFDDA 263