BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0017.0070.p (478 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J0V2.1 D8J0V2_HERSS Methylenomycin A resistance protein EC=3.6... 912 0.0 E3HLD7.1 E3HLD7_ACHXA Methylenomycin A resistance protein 443 e-122 E5U4T6.1 E5U4T6_ALCXX Major facilitator superfamily transporter ... 431 e-118 E8VE14.1 E8VE14_BACST Toxic compound efflux transporter 397 e-108 Q00538.1 MMR_BACSU Methylenomycin A resistance protein 392 e-106 D4G2T8.1 D4G2T8_BACNA Methylenomycin A resistance protein 389 e-106 C3HF40.1 C3HF40_BACTU Methylenomycin A resistance protein 388 e-105 C2YN27.1 C2YN27_BACCE Methylenomycin A resistance protein 385 e-105 C2VQ89.1 C2VQ89_BACCE Methylenomycin A resistance protein 380 e-103 C3BYW7.1 C3BYW7_BACTU Methylenomycin A resistance protein 367 2e-99 >D8J0V2.1 D8J0V2_HERSS Methylenomycin A resistance protein EC=3.6.3.- Length = 478 Score = 912 bits (2358), Expect = 0.0, Method: Compositional matrix adjust. Identities = 474/478 (99%), Positives = 474/478 (99%) Query: 1 MSCPSTPAAAALAAHPPAAGATLTPRAGMLPLVALAIGFVMAMLDVTVVNVGLSNIAGSL 60 MSCPSTPAAAALAAHPPAAGATLTPRAGMLPLVALAIGFVMAMLDVTVVNVGLSNIAGSL Sbjct: 1 MSCPSTPAAAALAAHPPAAGATLTPRAGMLPLVALAIGFVMAMLDVTVVNVGLSNIAGSL 60 Query: 61 DAPLSTLVWIVDGYTLTFAAMLLVGGALADRFGARRLYLTGLFLFVLASLLCGAAPNGPF 120 DAPLSTLVWIVDGYTLTFAAMLLVGGALADRFGARRLYLTGLFLFVLASLLCGAAPNGPF Sbjct: 61 DAPLSTLVWIVDGYTLTFAAMLLVGGALADRFGARRLYLTGLFLFVLASLLCGAAPNGPF 120 Query: 121 LIAARLLQGLGAAFFMPSSLSLLTHVYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIH 180 LI ARLLQGLGAAFFMPSSLSLLTHVYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIH Sbjct: 121 LIVARLLQGLGAAFFMPSSLSLLTHVYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIH 180 Query: 181 WLGWRSVFLINVPVGLVGLVMARKLIPQVAGHARALNLSSHLAGVVMLAGLSFVLIQGPV 240 WLGWRSVFLINVPVGLVGLVMARKLIPQV GHARALNLSSHLAGVVMLAGLSFVLIQGPV Sbjct: 181 WLGWRSVFLINVPVGLVGLVMARKLIPQVGGHARALNLSSHLAGVVMLAGLSFVLIQGPV 240 Query: 241 YGWTSPRILAGLAVVLLAGAALIRHELRGIAPLLPKALFATPQFAAANGIGFLINFGVYG 300 YGWTSPRILAGLAV L AGAALIRHELRGIAPLLPKALFATPQFAAANGIGFLINFGVYG Sbjct: 241 YGWTSPRILAGLAVALSAGAALIRHELRGIAPLLPKALFATPQFAAANGIGFLINFGVYG 300 Query: 301 NLFYLALFLQQGRGADALQTGLQLVPMMAVIFFGNLMSGRMSAHWGPRVPLLLGLSVGTV 360 NLFYLALFLQQGRGADALQTGLQLVPMMAVIFFGNLMSGRMSAHWGPRVPLLLGLSVGTV Sbjct: 301 NLFYLALFLQQGRGADALQTGLQLVPMMAVIFFGNLMSGRMSAHWGPRVPLLLGLSVGTV 360 Query: 361 FTALAMGFSPATPYWLLALVCASANLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQ 420 FTALAMGFSPATPYWLLALVCASANLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQ Sbjct: 361 FTALAMGFSPATPYWLLALVCASANLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQ 420 Query: 421 IGALVGVALMGAILHSVTGWNLRNPLAFGVMAAGYASALWLVWRFVGVVKEQWQVRRA 478 IGALVGVALMGAILHSVTGWNLRNPLAFGVMAAGYASALWLVWRFVGVVKEQWQVRRA Sbjct: 421 IGALVGVALMGAILHSVTGWNLRNPLAFGVMAAGYASALWLVWRFVGVVKEQWQVRRA 478 >E3HLD7.1 E3HLD7_ACHXA Methylenomycin A resistance protein Length = 466 Score = 443 bits (1140), Expect = e-122, Method: Compositional matrix adjust. Identities = 284/464 (61%), Positives = 337/464 (72%), Gaps = 10/464 (2%) Query: 2 SCPSTPAAAALAAHPPAAGATLTPRAGMLPLVALAIGFVMAMLDVTVVNVGLSNIAGSLD 61 +CP+ PA + L A P AAG +LPLV LAIGFVMAMLDVTVVNV L +IA Sbjct: 4 ACPNIPAPS-LDAKPAAAG--------LLPLVTLAIGFVMAMLDVTVVNVALPSIAVQFT 54 Query: 62 APLSTLVWIVDGYTLTFAAMLLVGGALADRFGARRLYLTGLFLFVLASLLCGAAPNGPFL 121 PL+ LVWIVDGYTLTFAA+LLV GALADR+GA+ +YL GL +F LASLLCG APN L Sbjct: 55 VPLTDLVWIVDGYTLTFAALLLVAGALADRYGAKTVYLAGLGVFTLASLLCGLAPNADLL 114 Query: 122 IAARLLQGLGAAFFMPSSLSLLTHVYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIHW 181 I AR+LQGLGAA FMPSSLSLLTH Y+D++ R RML WSA V +A A GPL+GGVLIH Sbjct: 115 ILARMLQGLGAALFMPSSLSLLTHAYDDEQTRNRMLAAWSAIVAVAGAAGPLLGGVLIHQ 174 Query: 182 LGWRSVFLINVPVGLVGLVMARKLIPQVAGHARALNLSSHLAGVVMLAGLSFVLIQGPVY 241 GWR +FLIN+P+GL GL +AR+ I RALN SHL GV+ L+ L FVLIQG Y Sbjct: 175 FGWRGIFLINIPLGLAGLWLARRRIQAAPRRPRALNPLSHLLGVIALSSLCFVLIQGNAY 234 Query: 242 GWTSPRILAGLAVVLLAGAALIRHELRGIAPLLPKALFATPQFAAANGIGFLINFGVYGN 301 GW+S IL A+ L A A L+R E R P++P+ALFAT QFAAANG+GFLIN YG Sbjct: 235 GWSSSLILGMAALCLAAAALLVRRERRHAEPIIPRALFATAQFAAANGVGFLINLASYGQ 294 Query: 302 LFYLALFLQQGRGADALQTGLQLVPMMAVIFFGNLMSGRMSAHWGPRVPLLLGLSVGTVF 361 LF L+LFLQQ RG DALQTGLQLVPM+AV GNLMSGR+SA W LL GLS+ + Sbjct: 295 LFLLSLFLQQARGTDALQTGLQLVPMLAVFSIGNLMSGRISARWNVSTALLGGLSLAAIM 354 Query: 362 TAL-AMGFSPATPYWLLALVCASANLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQ 420 +++ FSP YW A+ A +NLG+ A+PAMT+VVMQV+GK+HANSAAAALNANRQ Sbjct: 355 SSMGTFAFSPDMAYWPFAVAVALSNLGVGIAVPAMTSVVMQVSGKSHANSAAAALNANRQ 414 Query: 421 IGALVGVALMGAILHSVTGWNLRNPLAFGVMAAGYASALWLVWR 464 GALVGVALMG ILH + W+ P A+ ++ A Y +A+ LVWR Sbjct: 415 SGALVGVALMGTILHLLPDWHASLPAAYCIIGASYLAAVALVWR 458 >E5U4T6.1 E5U4T6_ALCXX Major facilitator superfamily transporter MFS_1 Length = 467 Score = 431 bits (1108), Expect = e-118, Method: Compositional matrix adjust. Identities = 279/464 (60%), Positives = 325/464 (70%), Gaps = 9/464 (1%) Query: 2 SCPSTPAAAALAAHPPAAGATLTPRAGMLPLVALAIGFVMAMLDVTVVNVGLSNIAGSLD 61 +C + P A P A G +LPLV LAIGFVMAMLDVTVVNV L +IA Sbjct: 4 ACSTAPLPVEPALRPAATG--------LLPLVTLAIGFVMAMLDVTVVNVALPSIAQQFT 55 Query: 62 APLSTLVWIVDGYTLTFAAMLLVGGALADRFGARRLYLTGLFLFVLASLLCGAAPNGPFL 121 PL+ LVWIVDGYTLTFAA+LLV GALADR+GA+ +YL GL +F LASLLCG AP G L Sbjct: 56 VPLTDLVWIVDGYTLTFAALLLVAGALADRYGAKTVYLAGLGVFTLASLLCGIAPGGDLL 115 Query: 122 IAARLLQGLGAAFFMPSSLSLLTHVYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIHW 181 IAAR+LQGLGAA FMPSSLSLLTH YEDD+VR RML WSA V +A A GPL+GGVLIH Sbjct: 116 IAARMLQGLGAALFMPSSLSLLTHAYEDDQVRNRMLAAWSAIVAVAGAAGPLLGGVLIHQ 175 Query: 182 LGWRSVFLINVPVGLVGLVMARKLIPQVAGHARALNLSSHLAGVVMLAGLSFVLIQGPVY 241 GWR +FLIN+P+GL GL +AR+ I RALN SH+ GVV L+ L F LIQG Y Sbjct: 176 FGWRGIFLINLPLGLAGLWLARRRIQAAPRRPRALNPLSHVFGVVALSSLCFALIQGNAY 235 Query: 242 GWTSPRILAGLAVVLLAGAALIRHELRGIAPLLPKALFATPQFAAANGIGFLINFGVYGN 301 GW S IL V LLA LI E P++P+ALF T QFAAANG+GFLIN YG Sbjct: 236 GWDSLPILGAALVFLLAATLLIHRERHHAEPIIPRALFQTTQFAAANGVGFLINLASYGQ 295 Query: 302 LFYLALFLQQGRGADALQTGLQLVPMMAVIFFGNLMSGRMSAHWGPRVPLLLGLSVGTVF 361 LF L+LFLQQ RGADAL+TG+QLVPM+AV GNL+S R+SA W LL G+ + TV Sbjct: 296 LFLLSLFLQQARGADALETGIQLVPMLAVFSIGNLISSRISARWNVSASLLGGILLATVM 355 Query: 362 TALAM-GFSPATPYWLLALVCASANLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQ 420 + + F+P PY A V A ANLG+ A+PAMT+VVMQV+GK HANSAAAALNANRQ Sbjct: 356 SLAGLAAFTPDMPYRPFAAVVALANLGVGIAVPAMTSVVMQVSGKHHANSAAAALNANRQ 415 Query: 421 IGALVGVALMGAILHSVTGWNLRNPLAFGVMAAGYASALWLVWR 464 GALVGVALMG ILH + W+ P ++ ++AA Y A LVWR Sbjct: 416 SGALVGVALMGTILHLLPDWHASLPASYVIIAAAYLVAAMLVWR 459 >E8VE14.1 E8VE14_BACST Toxic compound efflux transporter Length = 466 Score = 397 bits (1020), Expect = e-108, Method: Compositional matrix adjust. Identities = 215/444 (48%), Positives = 295/444 (66%), Gaps = 1/444 (0%) Query: 24 TPRAGMLPLVALAIGFVMAMLDVTVVNVGLSNIAGSLDAPLSTLVWIVDGYTLTFAAMLL 83 T G+ L+ LA+GF+MA LDVTVVNV ++++ +L LS + W+VDGY LTFA++LL Sbjct: 11 TSSTGISVLIVLALGFLMATLDVTVVNVAMADMKSTLSMSLSGVTWVVDGYILTFASLLL 70 Query: 84 VGGALADRFGARRLYLTGLFLFVLASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLL 143 GGALADRFG++ +Y+ GL +FVLAS LCGA+ NG LIA RL+QG+GAA FMPSSLSLL Sbjct: 71 AGGALADRFGSKTIYILGLAIFVLASCLCGASFNGQMLIAGRLIQGIGAALFMPSSLSLL 130 Query: 144 THVYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIHWLGWRSVFLINVPVGLVGLVMAR 203 Y D+R RARM G+W+A V A+A+GP +GGVL+ GW+S+FLINVP+G L+ A Sbjct: 131 AASYPDERARARMFGLWAALVSAASALGPFIGGVLVELAGWQSIFLINVPIGAAALISAY 190 Query: 204 KLIPQVAGHARALNLSSHLAGVVMLAGLSFVLIQGPVYGWTSPRILAGLAVVLLAGAALI 263 +++ +V G + +N+ HL G++ L LS+ LIQGP GW SP IL +LA + Sbjct: 191 RILSRVPGKSSRVNIIGHLLGMMALGFLSYALIQGPSAGWRSPVILVAFTAAILAFVLFL 250 Query: 264 RHELRGIAPLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQ 323 E+ AP+LP +L+ +F+AA IGFL+NF ++G +F L+LFLQ+ GA + G++ Sbjct: 251 LREISAKAPILPASLYKNGRFSAAQFIGFLLNFALFGGMFMLSLFLQEAGGASSFMAGVE 310 Query: 324 LVPMMAVIFFGNLMSGRMSAHWGPRVPLLLGLSVGTVFTALAMGF-SPATPYWLLALVCA 382 L+PMMAV GNL+ R++ + + + ++V + L SP PYW LA++ + Sbjct: 311 LLPMMAVFVIGNLLFARLANRFEAGQLMFVSMAVSCIIALLLFVLISPDFPYWQLAVLMS 370 Query: 383 SANLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAILHSVTGWNL 442 NL +PAMTTV+MQ AG+ HAN A AALNANRQIGALVGVA+ G I+H W Sbjct: 371 VMNLCTGITVPAMTTVIMQAAGQRHANIAGAALNANRQIGALVGVAITGVIIHLSATWYA 430 Query: 443 RNPLAFGVMAAGYASALWLVWRFV 466 F +M A Y+ A LVW F+ Sbjct: 431 GAGFTFLMMGASYSLAALLVWLFL 454 >Q00538.1 MMR_BACSU Methylenomycin A resistance protein Length = 466 Score = 392 bits (1006), Expect = e-106, Method: Compositional matrix adjust. Identities = 212/444 (47%), Positives = 293/444 (65%), Gaps = 1/444 (0%) Query: 24 TPRAGMLPLVALAIGFVMAMLDVTVVNVGLSNIAGSLDAPLSTLVWIVDGYTLTFAAMLL 83 T G+ L+ LA+GF+MA LDVTVVNV ++++ +L LS + W+VDGY LTFA++LL Sbjct: 11 TSSTGISVLIVLALGFLMATLDVTVVNVAMADMKNTLSMSLSGVTWVVDGYILTFASLLL 70 Query: 84 VGGALADRFGARRLYLTGLFLFVLASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLL 143 GGALADRFG++ +Y+ GL +FV+AS LC A+ NG LIA RL+QG+GAA FMPSSLSLL Sbjct: 71 AGGALADRFGSKTIYILGLAVFVMASCLCAASINGQMLIAGRLIQGIGAALFMPSSLSLL 130 Query: 144 THVYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIHWLGWRSVFLINVPVGLVGLVMAR 203 Y D+R RARM G+W+A V A+A+GP +GGVL+ GW+S+FLINVP+G L+ A Sbjct: 131 AASYLDERARARMFGLWAALVSAASALGPFIGGVLVQLAGWQSIFLINVPIGAAALISAY 190 Query: 204 KLIPQVAGHARALNLSSHLAGVVMLAGLSFVLIQGPVYGWTSPRILAGLAVVLLAGAALI 263 +++ +V G + +N+ HL G++ L LS+ LIQGP GW SP IL +LA + Sbjct: 191 RILSRVPGKSSRVNIIGHLLGMMALGFLSYALIQGPSAGWRSPVILVAFTAAVLAFVLFL 250 Query: 264 RHELRGIAPLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQ 323 E+ P+LP +L+ +F+AA IGFL+NF ++G +F L+LFLQ+ GA + G++ Sbjct: 251 LREISAKTPILPASLYKNGRFSAAQFIGFLLNFALFGGMFMLSLFLQEAGGASSFMAGVE 310 Query: 324 LVPMMAVIFFGNLMSGRMSAHWGPRVPLLLGLSVGTVFTALAMGF-SPATPYWLLALVCA 382 L+PMMAV GNL+ R++ + + + ++V + L SP PYW LA++ + Sbjct: 311 LLPMMAVFVIGNLLFARLANRFEAGQLMFVSMAVSCIIALLLFVLISPDFPYWQLAVLMS 370 Query: 383 SANLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAILHSVTGWNL 442 NL +PAMTTV+MQ AG+ H N A AALNANRQIGALVGVA+ G I+H W Sbjct: 371 VMNLCTGITVPAMTTVIMQAAGQRHTNIAGAALNANRQIGALVGVAITGVIIHLSATWYA 430 Query: 443 RNPLAFGVMAAGYASALWLVWRFV 466 AF +M A Y+ A LVW F+ Sbjct: 431 GAGFAFLMMGAAYSLAALLVWLFL 454 >D4G2T8.1 D4G2T8_BACNA Methylenomycin A resistance protein Length = 449 Score = 389 bits (999), Expect = e-106, Method: Compositional matrix adjust. Identities = 210/436 (48%), Positives = 290/436 (66%), Gaps = 1/436 (0%) Query: 32 LVALAIGFVMAMLDVTVVNVGLSNIAGSLDAPLSTLVWIVDGYTLTFAAMLLVGGALADR 91 L+ LA+GF+MA LDVTVVNV ++++ +L LS + W+VDGY LTFA++LL GGALADR Sbjct: 2 LIVLALGFLMATLDVTVVNVAMADMKNTLSMSLSGVTWVVDGYILTFASLLLAGGALADR 61 Query: 92 FGARRLYLTGLFLFVLASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLLTHVYEDDR 151 FG++ +Y+ GL +FV+AS LC A+ NG LIA RL+QG+GAA FMPSSLSLL Y D+R Sbjct: 62 FGSKTIYILGLAVFVMASCLCAASINGQMLIAGRLIQGIGAALFMPSSLSLLAASYLDER 121 Query: 152 VRARMLGVWSATVGLAAAVGPLVGGVLIHWLGWRSVFLINVPVGLVGLVMARKLIPQVAG 211 RARM G+W+A V A+A+GP +GGVL+ GW+S+FLINVP+G L+ A +++ +V G Sbjct: 122 ARARMFGLWAALVSAASALGPFIGGVLVQLAGWQSIFLINVPIGAAALISAYRILSRVPG 181 Query: 212 HARALNLSSHLAGVVMLAGLSFVLIQGPVYGWTSPRILAGLAVVLLAGAALIRHELRGIA 271 + +N+ HL G++ L LS+ LIQGP GW SP IL +LA + E+ Sbjct: 182 KSSRVNIIGHLLGMMALGFLSYALIQGPSAGWRSPVILVAFTAAVLAFVLFLLREISAKT 241 Query: 272 PLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQLVPMMAVI 331 P+LP +L+ +F+AA IGFL+NF ++G +F L+LFLQ+ GA + G++L+PMMAV Sbjct: 242 PILPASLYKNGRFSAAQFIGFLLNFALFGGMFMLSLFLQEAGGASSFMAGVELLPMMAVF 301 Query: 332 FFGNLMSGRMSAHWGPRVPLLLGLSVGTVFTALAMGF-SPATPYWLLALVCASANLGIST 390 GNL+ R++ + + + ++V + L SP PYW LA++ + NL Sbjct: 302 VIGNLLFARLANRFEAGQLMFVSMAVSCIIALLLFVLISPDFPYWQLAVLMSVMNLCTGI 361 Query: 391 AIPAMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAILHSVTGWNLRNPLAFGV 450 +PAMTTV+MQ AG+ H N A AALNANRQIGALVGVA+ G I+H W AF + Sbjct: 362 TVPAMTTVIMQAAGQRHTNIAGAALNANRQIGALVGVAITGVIIHLSATWYAGAGFAFLM 421 Query: 451 MAAGYASALWLVWRFV 466 M A Y+ A LVW F+ Sbjct: 422 MGAAYSLAALLVWLFL 437 >C3HF40.1 C3HF40_BACTU Methylenomycin A resistance protein Length = 459 Score = 388 bits (996), Expect = e-105, Method: Compositional matrix adjust. Identities = 202/443 (45%), Positives = 296/443 (66%) Query: 24 TPRAGMLPLVALAIGFVMAMLDVTVVNVGLSNIAGSLDAPLSTLVWIVDGYTLTFAAMLL 83 ++G++ L+ALA+GF+MA LDVTVVNV L NI +L L + WIVDGY L+FAA+LL Sbjct: 14 EEKSGIIILIALAMGFIMATLDVTVVNVALVNIQETLGLTLYSSTWIVDGYILSFAALLL 73 Query: 84 VGGALADRFGARRLYLTGLFLFVLASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLL 143 GGALA+RFGA+R+YL GL +FV ASLLC A G L+ R++QG+GAA FMPSSLSLL Sbjct: 74 AGGALANRFGAKRIYLIGLIIFVFASLLCTVATTGNALVIGRIIQGVGAALFMPSSLSLL 133 Query: 144 THVYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIHWLGWRSVFLINVPVGLVGLVMAR 203 + D++ RA+M G+WSA V +A+ GP +GG+L++ GWRS+F+IN+P+G++G++MA Sbjct: 134 VVSFPDEKKRAKMFGIWSAIVSIASGTGPFIGGLLVNTFGWRSIFIINLPIGMIGILMAF 193 Query: 204 KLIPQVAGHARALNLSSHLAGVVMLAGLSFVLIQGPVYGWTSPRILAGLAVVLLAGAALI 263 +IP + +N+ +HL G++ + L+F LI+GP YGW+SP+IL G+ +L + Sbjct: 194 VIIPNILPKKEKINVLNHLIGIIAITLLAFTLIEGPSYGWSSPQILGGVVGTVLTTILFV 253 Query: 264 RHELRGIAPLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQ 323 E + ++P+ LF F +AN +GFLINF ++G +F LFLQ+ GA GLQ Sbjct: 254 YAERKSKNSVVPRVLFQNETFISANIVGFLINFALFGGIFMFGLFLQKAYGASPFVAGLQ 313 Query: 324 LVPMMAVIFFGNLMSGRMSAHWGPRVPLLLGLSVGTVFTALAMGFSPATPYWLLALVCAS 383 L+PMM+V GN++ +M + + + L + L + ++ + L M Y +A++ + Sbjct: 314 LLPMMSVFVIGNVLFAKMVSKFSSKSLLFIALFIASIGSLLLMLLVNNVSYIGIAIIYSV 373 Query: 384 ANLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAILHSVTGWNLR 443 NLGI A+PAMTT+VM+ AG+ + N A A LN NRQIGALVG+A+MG IL+ + W Sbjct: 374 VNLGIGIAVPAMTTIVMKSAGRENGNMAGATLNVNRQIGALVGIAIMGIILNESSNWYRG 433 Query: 444 NPLAFGVMAAGYASALWLVWRFV 466 +F V+ Y A++LVW+FV Sbjct: 434 ASYSFLVIGLSYLCAVFLVWKFV 456 >C2YN27.1 C2YN27_BACCE Methylenomycin A resistance protein Length = 459 Score = 385 bits (990), Expect = e-105, Method: Compositional matrix adjust. Identities = 201/442 (45%), Positives = 292/442 (66%) Query: 25 PRAGMLPLVALAIGFVMAMLDVTVVNVGLSNIAGSLDAPLSTLVWIVDGYTLTFAAMLLV 84 ++G++ L+ LA+GF+MA LDVTVVN+ + NI +L L + WIVDGY L+FAA+LL Sbjct: 15 EKSGIVILITLAMGFIMATLDVTVVNIAVVNIQETLGLTLYSSTWIVDGYILSFAALLLA 74 Query: 85 GGALADRFGARRLYLTGLFLFVLASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLLT 144 GGALA+++GA+ +Y+ GL +FV ASLLC A NG LI R+LQG+GAA FMPSSLSLL Sbjct: 75 GGALANQYGAKNMYMVGLIIFVFASLLCAMATNGNTLIIGRVLQGVGAALFMPSSLSLLV 134 Query: 145 HVYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIHWLGWRSVFLINVPVGLVGLVMARK 204 + D++ RA+M G+WSA V +A+ GP +GG+L++ GWRS+F+IN+P+G++G++MA Sbjct: 135 VSFPDEKKRAKMFGIWSAIVSIASGTGPFIGGLLVNTFGWRSIFIINLPIGVIGVLMAFV 194 Query: 205 LIPQVAGHARALNLSSHLAGVVMLAGLSFVLIQGPVYGWTSPRILAGLAVVLLAGAALIR 264 +IP V +N+ +HL G+ + L+F LI+GP YGW+S +IL G+ +L + Sbjct: 195 IIPNVLPKKEKINVLNHLIGITTITLLAFTLIEGPSYGWSSFQILGGVVGTVLTAILFVY 254 Query: 265 HELRGIAPLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQL 324 E + ++P+ LF F++AN +GFL+NF V+G +F LFLQ+ GA GLQL Sbjct: 255 AERKSKNSVVPRVLFQNETFSSANIVGFLLNFAVFGGIFMFGLFLQKAYGASPFVAGLQL 314 Query: 325 VPMMAVIFFGNLMSGRMSAHWGPRVPLLLGLSVGTVFTALAMGFSPATPYWLLALVCASA 384 +PMM+V GNL+ +M +G ++ L + L + ++ + L M Y +A + + Sbjct: 315 LPMMSVFVIGNLLFAKMVTKFGSKLLLFIALFIASIGSLLLMFIVNNVSYIGIAFIYSIV 374 Query: 385 NLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAILHSVTGWNLRN 444 NLGI A+PAMTT+VM+ AG+ + N A A LN NRQIGALVG+A+MG IL+ + W Sbjct: 375 NLGIGIAVPAMTTIVMKSAGRENGNMAGATLNVNRQIGALVGIAIMGIILNESSNWYRGA 434 Query: 445 PLAFGVMAAGYASALWLVWRFV 466 +F VM Y A LVW+FV Sbjct: 435 SYSFLVMGIAYLCATMLVWKFV 456 >C2VQ89.1 C2VQ89_BACCE Methylenomycin A resistance protein Length = 459 Score = 380 bits (977), Expect = e-103, Method: Compositional matrix adjust. Identities = 199/443 (44%), Positives = 292/443 (65%) Query: 24 TPRAGMLPLVALAIGFVMAMLDVTVVNVGLSNIAGSLDAPLSTLVWIVDGYTLTFAAMLL 83 ++G++ L+ALA+GF+MA LDVTVVNV + NI +L L + WIVDGY L+FAA LL Sbjct: 14 EEKSGIIILIALAMGFIMATLDVTVVNVAVVNIQETLGMTLYSSTWIVDGYILSFAAFLL 73 Query: 84 VGGALADRFGARRLYLTGLFLFVLASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLL 143 GGALA++FGA+++YL GL +FV ASLLC A G L+ R++QG+GAA FMPSSLSLL Sbjct: 74 AGGALANQFGAKKIYLIGLIIFVFASLLCTVATTGNTLVIGRIIQGVGAALFMPSSLSLL 133 Query: 144 THVYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIHWLGWRSVFLINVPVGLVGLVMAR 203 + D++ RA+M G+WSA V +A+ GP +GG+L++ GWRS+F+IN+P+G++G++MA Sbjct: 134 VVSFPDEKKRAKMFGIWSAIVSIASGTGPFIGGLLVNTFGWRSIFIINLPIGMIGILMAF 193 Query: 204 KLIPQVAGHARALNLSSHLAGVVMLAGLSFVLIQGPVYGWTSPRILAGLAVVLLAGAALI 263 +IP V +N+ +HL G++ + L+F LI+GP YGW+SP+IL G+ +L + Sbjct: 194 VIIPNVLPKKEKINVLNHLIGIIAITLLAFTLIEGPSYGWSSPQILGGVVGTVLTTILFV 253 Query: 264 RHELRGIAPLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQ 323 E + ++P+ L F AN +GFLINF ++G +F LFLQ+ GA GLQ Sbjct: 254 YAERKSKNSVVPRVLLQNETFILANIVGFLINFALFGGIFMFGLFLQKAHGASPFVAGLQ 313 Query: 324 LVPMMAVIFFGNLMSGRMSAHWGPRVPLLLGLSVGTVFTALAMGFSPATPYWLLALVCAS 383 L+PMM+V GN++ +M + + + L + L + ++ + L M Y +A++ + Sbjct: 314 LLPMMSVFVIGNILFAKMVSKFSSKSLLFIALFIASIGSLLLMLLVNNVSYIGIAIIYSV 373 Query: 384 ANLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAILHSVTGWNLR 443 NLGI A+PAMTT+VM+ AG+ + N A A LN NRQIGALVG+A+MG IL+ + W Sbjct: 374 VNLGIGIAVPAMTTIVMKSAGRENGNMAGATLNVNRQIGALVGIAIMGIILNESSNWYRG 433 Query: 444 NPLAFGVMAAGYASALWLVWRFV 466 +F V+ Y A +LVW+FV Sbjct: 434 ASYSFLVIGFSYLCAAFLVWKFV 456 >C3BYW7.1 C3BYW7_BACTU Methylenomycin A resistance protein Length = 456 Score = 367 bits (943), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 199/443 (44%), Positives = 295/443 (66%) Query: 24 TPRAGMLPLVALAIGFVMAMLDVTVVNVGLSNIAGSLDAPLSTLVWIVDGYTLTFAAMLL 83 ++G++ L+ALA+GF+MA LDVTVVNV + NI +L L + WIVDGY L+FAA+LL Sbjct: 11 KEKSGIIILIALAMGFIMATLDVTVVNVAVVNIQETLGLTLYSSTWIVDGYILSFAALLL 70 Query: 84 VGGALADRFGARRLYLTGLFLFVLASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLL 143 GGALA++FGA+++YL GL +FV ASLLC A G L+ R++QG+GAA FMPSSLSLL Sbjct: 71 AGGALANQFGAKKIYLIGLIIFVFASLLCTVATTGNTLVIGRIIQGVGAALFMPSSLSLL 130 Query: 144 THVYEDDRVRARMLGVWSATVGLAAAVGPLVGGVLIHWLGWRSVFLINVPVGLVGLVMAR 203 + D++ RA+M G+WSA V +A+ GP +GG+L++ GWRS+F+IN+P+G++G++MA Sbjct: 131 VVSFPDEKKRAKMFGIWSAIVSIASGTGPFIGGLLVNTFGWRSIFIINLPIGMIGILMAF 190 Query: 204 KLIPQVAGHARALNLSSHLAGVVMLAGLSFVLIQGPVYGWTSPRILAGLAVVLLAGAALI 263 +IP V + +++HL G++ + L+F LI+GP YGW+SP+IL G+ +L + Sbjct: 191 VIIPNVLPKKEKIKVANHLIGIIAITLLAFTLIEGPSYGWSSPQILGGVVGTVLTMILFV 250 Query: 264 RHELRGIAPLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQ 323 E + ++P+ LF F +AN +GFLINF ++G +F LFLQ+ GA GLQ Sbjct: 251 YAERKSKNSVVPRVLFQNETFISANIVGFLINFALFGGIFMFGLFLQKAYGASPFVAGLQ 310 Query: 324 LVPMMAVIFFGNLMSGRMSAHWGPRVPLLLGLSVGTVFTALAMGFSPATPYWLLALVCAS 383 L+PMM+V GN++ +M + + + L + L + ++ + L M Y +A++ + Sbjct: 311 LLPMMSVFVIGNILFAKMVSKFSSKSLLFIALFIASIGSILLMLVVNNVSYIGIAIIYSV 370 Query: 384 ANLGISTAIPAMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAILHSVTGWNLR 443 NLGI A+PAMTT+VM+ AG+ + N A A LN NRQIGALVG+A+MG IL+ W Sbjct: 371 VNLGIGIAVPAMTTIVMKSAGRENGNMAGATLNVNRQIGALVGIAIMGIILNESPNWYKG 430 Query: 444 NPLAFGVMAAGYASALWLVWRFV 466 +F V+ Y A++LVW+FV Sbjct: 431 ASNSFLVIGIAYLCAVFLVWKFV 453