BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0017.0068.p (288 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J0V1.1 D8J0V1_HERSS LysR family transcription regulator protein 588 e-166 D4XH73.1 D4XH73_9BURK LysR family transcriptional regulator 377 e-102 E5U4T5.1 E5U4T5_ALCXX Transcriptional regulator 360 1e-97 A9HWX7.1 A9HWX7_BORPD Transcriptional regulator, LysR-family 352 5e-95 E3HLD6.1 E3HLD6_ACHXA Bacterial regulatory helix-turn-helix prot... 346 3e-93 Q46N14.1 Q46N14_CUPPJ Transcriptional regulator, LysR family 306 2e-81 C6BBI7.1 C6BBI7_RALP1 Transcriptional regulator, LysR family 301 7e-80 F0G6A0.1 F0G6A0_9BURK LysR family transcriptional regulator 298 6e-79 Q390G1.1 Q390G1_BURS3 Transcriptional regulator, LysR family 296 2e-78 B4EGV6.1 B4EGV6_BURCJ LysR family regulatory protein 294 1e-77 >D8J0V1.1 D8J0V1_HERSS LysR family transcription regulator protein Length = 288 Score = 588 bits (1515), Expect = e-166, Method: Compositional matrix adjust. Identities = 288/288 (100%), Positives = 288/288 (100%) Query: 1 MDWDNARIFLAIYRVGTLRGAAETLELDQATVGRRLAALERSLGARLFLRTPNGYVPTPA 60 MDWDNARIFLAIYRVGTLRGAAETLELDQATVGRRLAALERSLGARLFLRTPNGYVPTPA Sbjct: 1 MDWDNARIFLAIYRVGTLRGAAETLELDQATVGRRLAALERSLGARLFLRTPNGYVPTPA 60 Query: 61 GEMAAAAAQQMEQGAEQLQRQMQGIDERLCGVVRLAATDVTARHFLIPALHRLRQEHPHI 120 GEMAAAAAQQMEQGAEQLQRQMQGIDERLCGVVRLAATDVTARHFLIPALHRLRQEHPHI Sbjct: 61 GEMAAAAAQQMEQGAEQLQRQMQGIDERLCGVVRLAATDVTARHFLIPALHRLRQEHPHI 120 Query: 121 RVVLSTSTQITNLTKREADIAVRTLRPDAPDLIARHLKRLHTAIYASRSYVKKRGLPEPG 180 RVVLSTSTQITNLTKREADIAVRTLRPDAPDLIARHLKRLHTAIYASRSYVKKRGLPEPG Sbjct: 121 RVVLSTSTQITNLTKREADIAVRTLRPDAPDLIARHLKRLHTAIYASRSYVKKRGLPEPG 180 Query: 181 TGLKGHDVVIYQRSVSPAKSEQICGESIINAQVAMEVSTGLVMYDCLQAGFGLGELPTHV 240 TGLKGHDVVIYQRSVSPAKSEQICGESIINAQVAMEVSTGLVMYDCLQAGFGLGELPTHV Sbjct: 181 TGLKGHDVVIYQRSVSPAKSEQICGESIINAQVAMEVSTGLVMYDCLQAGFGLGELPTHV 240 Query: 241 GDKASGLVRVWPQRETPYDMWLVLHSDLNRTARVRAVADAIIAAYEAA 288 GDKASGLVRVWPQRETPYDMWLVLHSDLNRTARVRAVADAIIAAYEAA Sbjct: 241 GDKASGLVRVWPQRETPYDMWLVLHSDLNRTARVRAVADAIIAAYEAA 288 >D4XH73.1 D4XH73_9BURK LysR family transcriptional regulator Length = 289 Score = 377 bits (967), Expect = e-102, Method: Compositional matrix adjust. Identities = 177/286 (61%), Positives = 222/286 (77%) Query: 1 MDWDNARIFLAIYRVGTLRGAAETLELDQATVGRRLAALERSLGARLFLRTPNGYVPTPA 60 MDWDNARIFLAIYRVGTLRGAA L++DQAT GRRLAALE SL ARLFLRTP GYVPTPA Sbjct: 1 MDWDNARIFLAIYRVGTLRGAAALLQIDQATAGRRLAALESSLDARLFLRTPGGYVPTPA 60 Query: 61 GEMAAAAAQQMEQGAEQLQRQMQGIDERLCGVVRLAATDVTARHFLIPALHRLRQEHPHI 120 GE+A AAA++MEQ A+QLQRQMQG+D RL GVVR+AA++ A +F++ A+ R++ +HP I Sbjct: 61 GELAFAAAERMEQAADQLQRQMQGLDHRLSGVVRVAASETVASYFVMEAVRRVQAQHPDI 120 Query: 121 RVVLSTSTQITNLTKREADIAVRTLRPDAPDLIARHLKRLHTAIYASRSYVKKRGLPEPG 180 RVVLS S QI+NLT+READ+A+R L+PD PDLI RHL R +YASR Y+ G P PG Sbjct: 121 RVVLSASIQISNLTRREADLAIRNLKPDNPDLIQRHLARKEVGLYASRGYLAAHGEPRPG 180 Query: 181 TGLKGHDVVIYQRSVSPAKSEQICGESIINAQVAMEVSTGLVMYDCLQAGFGLGELPTHV 240 T GH +V YQ++V P S+ CGE N ++A+E+++G+++ + AG G+GELPTH+ Sbjct: 181 TAFAGHTLVTYQQAVLPGWSDTFCGEPTGNGRIAIELNSGMMILAAVAAGLGIGELPTHM 240 Query: 241 GDKASGLVRVWPQRETPYDMWLVLHSDLNRTARVRAVADAIIAAYE 286 LVR+WP R PYD+WLV+H DLNRTARVRAVADAI+ +E Sbjct: 241 APDYPDLVRIWPGRAEPYDLWLVMHGDLNRTARVRAVADAIVEVFE 286 >E5U4T5.1 E5U4T5_ALCXX Transcriptional regulator Length = 288 Score = 360 bits (924), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 175/286 (61%), Positives = 221/286 (77%) Query: 1 MDWDNARIFLAIYRVGTLRGAAETLELDQATVGRRLAALERSLGARLFLRTPNGYVPTPA 60 MDWDNARIFLAIYR GTLRGAA L++DQAT GRRLAALE SL ARLFLRTP+GYVPT A Sbjct: 1 MDWDNARIFLAIYRNGTLRGAAALLQIDQATAGRRLAALEASLDARLFLRTPSGYVPTAA 60 Query: 61 GEMAAAAAQQMEQGAEQLQRQMQGIDERLCGVVRLAATDVTARHFLIPALHRLRQEHPHI 120 GE A AAA++MEQ A+QLQRQMQG+D RL GVVR+A ++ A +F++ A+ RL +HP I Sbjct: 61 GEQAFAAAERMEQAADQLQRQMQGLDHRLSGVVRVATSETVASYFIMEAISRLHVQHPDI 120 Query: 121 RVVLSTSTQITNLTKREADIAVRTLRPDAPDLIARHLKRLHTAIYASRSYVKKRGLPEPG 180 RV LSTS Q++NLT+READ+A+R ++PD PDLI RHL R +YASRSY++ G P PG Sbjct: 121 RVALSTSIQLSNLTRREADLAIRNIKPDNPDLIQRHLARKEVGLYASRSYLEAHGEPRPG 180 Query: 181 TGLKGHDVVIYQRSVSPAKSEQICGESIINAQVAMEVSTGLVMYDCLQAGFGLGELPTHV 240 T GH +V YQ++V P S+ CGE N ++AME+++GL++ + + AG G+GELP H+ Sbjct: 181 TAFAGHTLVTYQQAVLPGWSDTFCGEPTGNGRIAMELNSGLMIIEAVAAGLGIGELPIHM 240 Query: 241 GDKASGLVRVWPQRETPYDMWLVLHSDLNRTARVRAVADAIIAAYE 286 + LVR+WP R PYD+WLV+H DLNRTARVRAVADAI+ +E Sbjct: 241 APQYPDLVRIWPHRSEPYDLWLVMHGDLNRTARVRAVADAIVEVFE 286 >A9HWX7.1 A9HWX7_BORPD Transcriptional regulator, LysR-family Length = 289 Score = 352 bits (902), Expect = 5e-95, Method: Compositional matrix adjust. Identities = 177/286 (61%), Positives = 217/286 (75%) Query: 1 MDWDNARIFLAIYRVGTLRGAAETLELDQATVGRRLAALERSLGARLFLRTPNGYVPTPA 60 M+WD+ARIFLAIYRVGTLRGAA L++DQAT GRRLAA+E SL ARLFLRTP GYVPT A Sbjct: 1 MNWDDARIFLAIYRVGTLRGAAAVLQVDQATAGRRLAAIEASLQARLFLRTPRGYVPTAA 60 Query: 61 GEMAAAAAQQMEQGAEQLQRQMQGIDERLCGVVRLAATDVTARHFLIPALHRLRQEHPHI 120 GE+A AAA++MEQ A+QLQRQ+QG+D RL GVVR+A +D RH+L+ A R++ EHP I Sbjct: 61 GELAFAAAERMEQAADQLQRQLQGLDARLSGVVRVATSDTLGRHYLLEAFKRVQVEHPDI 120 Query: 121 RVVLSTSTQITNLTKREADIAVRTLRPDAPDLIARHLKRLHTAIYASRSYVKKRGLPEPG 180 RVVLSTSTQITNLT+READIAVR +RPD PDLI RHL R +YAS +YV++ G P G Sbjct: 121 RVVLSTSTQITNLTRREADIAVRNVRPDNPDLIHRHLARREMGLYASAAYVQEHGEPRLG 180 Query: 181 TGLKGHDVVIYQRSVSPAKSEQICGESIINAQVAMEVSTGLVMYDCLQAGFGLGELPTHV 240 T GH +V YQRS P + + CGE N QV +EV++GL+M + + G G+GELP + Sbjct: 181 TAFAGHRLVAYQRSAIPGRLDAFCGEPTRNGQVVLEVNSGLMMLEAVVRGLGIGELPVML 240 Query: 241 GDKASGLVRVWPQRETPYDMWLVLHSDLNRTARVRAVADAIIAAYE 286 LVR+WPQR YD+WLVLH DL R+ARVRA+ADAI+ +E Sbjct: 241 AGTYPALVRLWPQRAESYDLWLVLHGDLRRSARVRAIADAIVQVFE 286 >E3HLD6.1 E3HLD6_ACHXA Bacterial regulatory helix-turn-helix protein, LysR family protein 158 Length = 296 Score = 346 bits (887), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 168/286 (58%), Positives = 220/286 (76%) Query: 1 MDWDNARIFLAIYRVGTLRGAAETLELDQATVGRRLAALERSLGARLFLRTPNGYVPTPA 60 MDWDNARIFLAIYRVGTLRGAA L++DQAT GRRLAALE SL ARLFLRTP GYVPT A Sbjct: 8 MDWDNARIFLAIYRVGTLRGAAALLQVDQATAGRRLAALEASLDARLFLRTPGGYVPTAA 67 Query: 61 GEMAAAAAQQMEQGAEQLQRQMQGIDERLCGVVRLAATDVTARHFLIPALHRLRQEHPHI 120 GE+A AAA++MEQ A+QLQRQMQG+D RL GVVR+A ++ A ++++ A+ R+ HP I Sbjct: 68 GELAFAAAERMEQAADQLQRQMQGLDHRLSGVVRVATSETVATYYVMEAVRRVHAHHPDI 127 Query: 121 RVVLSTSTQITNLTKREADIAVRTLRPDAPDLIARHLKRLHTAIYASRSYVKKRGLPEPG 180 RV LST+ Q++NLT+READ+A+R +RPD PDLI RHL R +YAS++Y++ G P G Sbjct: 128 RVTLSTAIQLSNLTRREADLAIRNIRPDNPDLIHRHLARKEVGLYASKAYLEAHGEPRLG 187 Query: 181 TGLKGHDVVIYQRSVSPAKSEQICGESIINAQVAMEVSTGLVMYDCLQAGFGLGELPTHV 240 T GH +V YQ++V P S+ CGE N ++ +E+++GL++ + + AG G+G++PTH+ Sbjct: 188 TAFAGHTLVTYQQAVLPGWSDTFCGEPTGNGRMGVELNSGLMIIEAVAAGLGIGQVPTHM 247 Query: 241 GDKASGLVRVWPQRETPYDMWLVLHSDLNRTARVRAVADAIIAAYE 286 + LVR+WP R PYD+WLV+H DLNRTARVRAVADAI+ +E Sbjct: 248 APQYPDLVRIWPARSEPYDLWLVMHGDLNRTARVRAVADAIVEVFE 293 >Q46N14.1 Q46N14_CUPPJ Transcriptional regulator, LysR family Length = 290 Score = 306 bits (784), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 153/290 (52%), Positives = 206/290 (71%), Gaps = 3/290 (1%) Query: 1 MDWDNARIFLAIYRVGTLRGAAETLELDQATVGRRLAALERSLGARLFLRTPNGYVPTPA 60 M+W++ R+FLA+ R TLR AA+ + +DQATVGRR+AALE +LGA LFLRT +GYV T A Sbjct: 1 MNWNDTRVFLAVQRERTLRRAAKVVNMDQATVGRRIAALEHALGATLFLRTSDGYVLTSA 60 Query: 61 GEMAAAAAQQMEQGAEQLQRQMQGIDERLCGVVRLAATDVTARHFLIPALHRLRQEHPHI 120 GE A +A++MEQ A +L RQ QGID RL G VR+ TD A FLIPA+ RL EHP + Sbjct: 61 GENALRSAEKMEQSAHELARQAQGIDTRLEGEVRVTTTDTLALAFLIPAIERLHAEHPDV 120 Query: 121 RVVLSTSTQITNLTKREADIAVRTLRPDAPDLIARHLKRLHTAIYASRSYVKKRGLPEPG 180 RV+L+TSTQ+ NL +READIAVRT++PD PDL AR L R +YASR+Y+K+ G P G Sbjct: 121 RVLLNTSTQMMNLARREADIAVRTIKPDNPDLAARLLARWTVGLYASRTYLKRHGEPAVG 180 Query: 181 TGLKGHDVVIYQRSVSPAKSEQICGESIINAQVAMEVSTGLVMYDCLQAGFGLGELPTHV 240 TG GHD+VIYQ S ++ + GE ++ V++ L++ ++AG +GE+P H+ Sbjct: 181 TGFAGHDLVIYQPHTSGSRLPTLVGEPTHTGRLVSAVNSSLMLRATIRAGIAIGEVPVHL 240 Query: 241 GDKASGLVRVWPQRE--TPYDMWLVLHSDLNRTARVRAVADAIIAAYEAA 288 ++ GLVR+WP+RE PY++WLV H DL TARVRA+ DAI+A +E + Sbjct: 241 AER-DGLVRIWPKRERAQPYEVWLVTHQDLRHTARVRAMIDAIVAEFEGS 289 >C6BBI7.1 C6BBI7_RALP1 Transcriptional regulator, LysR family Length = 294 Score = 301 bits (771), Expect = 7e-80, Method: Compositional matrix adjust. Identities = 150/287 (52%), Positives = 196/287 (68%) Query: 1 MDWDNARIFLAIYRVGTLRGAAETLELDQATVGRRLAALERSLGARLFLRTPNGYVPTPA 60 M+WDN R FLA+ R GTLRGAA+ L +DQATVGRR+AALE L A+LFLRT V TPA Sbjct: 1 MNWDNGRFFLAVARTGTLRGAAQRLGVDQATVGRRIAALEDELSAKLFLRTSTALVLTPA 60 Query: 61 GEMAAAAAQQMEQGAEQLQRQMQGIDERLCGVVRLAATDVTARHFLIPALHRLRQEHPHI 120 GE A+ MEQ A ++R++ GID++L G +R+A TD A F++PA+ +LRQ HP I Sbjct: 61 GEALIGPAEAMEQAAHTIERRVAGIDDQLAGTIRVATTDTMAATFVLPAIAQLRQRHPGI 120 Query: 121 RVVLSTSTQITNLTKREADIAVRTLRPDAPDLIARHLKRLHTAIYASRSYVKKRGLPEPG 180 VV S I NLTKREAD+AVRTLRPD+PDLIAR + ++ T IYASRSYV RG PE G Sbjct: 121 DVVCMASKSIANLTKREADVAVRTLRPDSPDLIARRIGQMETGIYASRSYVAARGEPEEG 180 Query: 181 TGLKGHDVVIYQRSVSPAKSEQICGESIINAQVAMEVSTGLVMYDCLQAGFGLGELPTHV 240 T GHD+V+Y R+ P E +CGE I +V ++ ++ L + + + AG G+ EL Sbjct: 181 TAFAGHDLVLYPRNEVPWMWEDLCGEPITRGRVVLQSNSALALCEAVAAGIGMTELVCRR 240 Query: 241 GDKASGLVRVWPQRETPYDMWLVLHSDLNRTARVRAVADAIIAAYEA 287 LVRV P R + D+WLV H+DL++TARVRA+ D I+ A++A Sbjct: 241 AQAYPQLVRVLPNRRSMQDVWLVTHADLHKTARVRALLDCIVEAFDA 287 >F0G6A0.1 F0G6A0_9BURK LysR family transcriptional regulator Length = 290 Score = 298 bits (763), Expect = 6e-79, Method: Compositional matrix adjust. Identities = 149/289 (51%), Positives = 203/289 (70%), Gaps = 3/289 (1%) Query: 1 MDWDNARIFLAIYRVGTLRGAAETLELDQATVGRRLAALERSLGARLFLRTPNGYVPTPA 60 M+WD+AR+FLAI+R TLR AA+TL +DQATVGRRLA LE LGA LFLR+ GY+PTP Sbjct: 1 MNWDDARVFLAIHRERTLRRAAQTLGVDQATVGRRLATLEHQLGATLFLRSSKGYLPTPV 60 Query: 61 GEMAAAAAQQMEQGAEQLQRQMQGIDERLCGVVRLAATDVTARHFLIPALHRLRQEHPHI 120 GE+A AA+ MEQ A +L R QG+D RL G V++ TD A F++P++ RL +HP + Sbjct: 61 GELALRAAEAMEQHAHELVRLTQGVDRRLAGDVKVTTTDALAIEFVMPSIARLHAKHPDV 120 Query: 121 RVVLSTSTQITNLTKREADIAVRTLRPDAPDLIARHLKRLHTAIYASRSYVKKRGLPEPG 180 V L+TSTQ+ NL KREADIAVRT+RP PDL+AR L R ++AS Y+++ G P G Sbjct: 121 CVSLNTSTQVLNLAKREADIAVRTVRPANPDLVARRLARWDMGLFASPDYLQRHGEPTRG 180 Query: 181 TGLKGHDVVIYQRSVSPAKSEQICGESIINAQVAMEVSTGLVMYDCLQAGFGLGELPTHV 240 T GHD+V+YQ + ++ I GE I +A++ +++ L+M L+AG G+GE+P ++ Sbjct: 181 TAFAGHDLVVYQPYIDASRRPAIAGEPIGDARIVARMNSSLMMRAALRAGLGIGEIPVYM 240 Query: 241 GDKASGLVRVWPQ--RETPYDMWLVLHSDLNRTARVRAVADAIIAAYEA 287 G++ GLVRVWP RE PY++WLV H DL TAR+RA D I+ A++A Sbjct: 241 GER-DGLVRVWPGQLREAPYEVWLVTHRDLRHTARIRATIDEIVFAFDA 288 >Q390G1.1 Q390G1_BURS3 Transcriptional regulator, LysR family Length = 297 Score = 296 bits (759), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 146/289 (50%), Positives = 202/289 (69%), Gaps = 3/289 (1%) Query: 1 MDWDNARIFLAIYRVGTLRGAAETLELDQATVGRRLAALERSLGARLFLRTPNGYVPTPA 60 M+WD+AR+FLAI+R TLR AA+TL +DQATVGRRLA LE LGA LFLR+ GY+ TP Sbjct: 8 MNWDDARVFLAIHRERTLRRAAQTLGVDQATVGRRLAQLEHMLGATLFLRSSKGYLTTPV 67 Query: 61 GEMAAAAAQQMEQGAEQLQRQMQGIDERLCGVVRLAATDVTARHFLIPALHRLRQEHPHI 120 GE+A AA+ MEQ A +L R QG+D RL G V++ TD A F++P++ RL +HP + Sbjct: 68 GELALRAAEAMEQHAHELVRLTQGVDRRLAGEVKITTTDALALEFVMPSIARLHAKHPDV 127 Query: 121 RVVLSTSTQITNLTKREADIAVRTLRPDAPDLIARHLKRLHTAIYASRSYVKKRGLPEPG 180 V L+T+TQ+ NL KREADIAVRT+RPD PDL+AR L ++AS Y+++ G P G Sbjct: 128 CVSLNTATQVLNLAKREADIAVRTVRPDNPDLVARRLACWDMGLFASHDYLQRHGEPARG 187 Query: 181 TGLKGHDVVIYQRSVSPAKSEQICGESIINAQVAMEVSTGLVMYDCLQAGFGLGELPTHV 240 + GHD+V+YQ V ++ I GE I ++ +++ L+M L++G G+GE+P H+ Sbjct: 188 SAFAGHDLVVYQPYVDASRKPAIAGEPIAAGRIVGRMNSSLMMRAALRSGLGIGEVPVHM 247 Query: 241 GDKASGLVRVWPQ--RETPYDMWLVLHSDLNRTARVRAVADAIIAAYEA 287 G++ GL R+WP+ RETPY++WLV H DL TAR+RA D I+AA++A Sbjct: 248 GER-DGLARIWPEQTRETPYEVWLVTHRDLRHTARIRATIDEIVAAFDA 295 >B4EGV6.1 B4EGV6_BURCJ LysR family regulatory protein Length = 296 Score = 294 bits (752), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 144/285 (50%), Positives = 196/285 (68%) Query: 1 MDWDNARIFLAIYRVGTLRGAAETLELDQATVGRRLAALERSLGARLFLRTPNGYVPTPA 60 M+WDNAR FLA+ R GTLRGAA L +DQATVGRR+AALE L ARLFLRTP YV T A Sbjct: 1 MNWDNARFFLALARTGTLRGAAAQLNVDQATVGRRIAALEDELSARLFLRTPTLYVLTTA 60 Query: 61 GEMAAAAAQQMEQGAEQLQRQMQGIDERLCGVVRLAATDVTARHFLIPALHRLRQEHPHI 120 GE A+ ME+ + ++R++ G+DE+L G VR+A TD + F++PA+ R+R++H I Sbjct: 61 GEALLEPAETMERASLTIERRVMGLDEQLAGSVRIATTDTLGKRFVVPAIARVRRKHAGI 120 Query: 121 RVVLSTSTQITNLTKREADIAVRTLRPDAPDLIARHLKRLHTAIYASRSYVKKRGLPEPG 180 VV TS QITNLT+READ+A+RTLRP++PDLI R L L T IYASR Y+ +RG P G Sbjct: 121 DVVCVTSAQITNLTRREADLAIRTLRPESPDLIVRRLGHLETGIYASRRYLAERGEPVAG 180 Query: 181 TGLKGHDVVIYQRSVSPAKSEQICGESIINAQVAMEVSTGLVMYDCLQAGFGLGELPTHV 240 + GHD+V+YQ+ V P + +CGE +V + S+ +++ + AG G+ ELP Sbjct: 181 SAFDGHDLVMYQQPVVPTMWDALCGEPTSRGRVMFQTSSTMMLVEATLAGLGIAELPCFR 240 Query: 241 GDKASGLVRVWPQRETPYDMWLVLHSDLNRTARVRAVADAIIAAY 285 D LVR+ PQR +D+WLV H+DL +TARV+AV +A++ + Sbjct: 241 ADTEPELVRLMPQRCNHFDVWLVAHTDLYKTARVQAVIEAVVDEF 285