BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0013.0052.p (254 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J0A5.1 D8J0A5_HERSS 3-hydroxyacyl-CoA (Short-chain) dehydrogen... 500 e-140 Q135A9.1 Q135A9_RHOPS Short-chain dehydrogenase/reductase SDR 325 5e-87 Q6N7F4.1 Q6N7F4_RHOPA Putative 3-hydroxyacyl-CoA dehydrogenase E... 323 1e-86 E6VEM7.1 E6VEM7_RHOPX Short-chain dehydrogenase/reductase SDR 323 1e-86 B3QFI6.1 B3QFI6_RHOPT Short-chain dehydrogenase/reductase SDR 323 1e-86 Q1DGL1.1 Q1DGL1_AEDAE Hydroxyacyl dehydrogenase 320 8e-86 C1DLN4.1 C1DLN4_AZOVD Short-chain dehydrogenase/reductase SDR 313 1e-83 Q1BV50.1 Q1BV50_BURCA Short-chain dehydrogenase/reductase SDR 313 1e-83 A0KCQ0.1 A0KCQ0_BURCH Short-chain dehydrogenase/reductase SDR 313 1e-83 B1G822.1 B1G822_9BURK Short-chain dehydrogenase/reductase SDR 313 1e-83 >D8J0A5.1 D8J0A5_HERSS 3-hydroxyacyl-CoA (Short-chain) dehydrogenase type II oxidoreductase protein EC=1.1.1.35 Length = 254 Score = 500 bits (1288), Expect = e-140, Method: Compositional matrix adjust. Identities = 251/254 (98%), Positives = 251/254 (98%) Query: 1 MAVKQGVYVVTGAASGLGAATAEQLIRGGAKVVLADVNPVAGEKMQATLGANARFVLTDV 60 MAVKQGVYVVTGAASGLGAATAEQLIR GAKVVLADVNPVAGEKMQATLGANARFVLTDV Sbjct: 1 MAVKQGVYVVTGAASGLGAATAEQLIRAGAKVVLADVNPVAGEKMQATLGANARFVLTDV 60 Query: 61 TSETSAQEVLGVASSMGAVVGLVNCAGIAPGEKLLGKGGVHRLDSFMRALNINLVGSFNM 120 TSETSAQEV GVASSMGAVVGLVNCAGIAPGEKLLGKGGVHRLDSFMRALNINLVGSFNM Sbjct: 61 TSETSAQEVFGVASSMGAVVGLVNCAGIAPGEKLLGKGGVHRLDSFMRALNINLVGSFNM 120 Query: 121 ARLAAQHISAGPADAAGERGVIIHTASIAAFDGQMGQVAYAASKGGVVSMTLPMARELAR 180 ARLAAQHISAGPADA GERGVIIHTASIAAFDGQMGQVAYAASKGGVVSMTLPMARELAR Sbjct: 121 ARLAAQHISAGPADATGERGVIIHTASIAAFDGQMGQVAYAASKGGVVSMTLPMARELAR 180 Query: 181 HGIRVVTIAPGIIETPMMLGMPEEVLESLSRNVPFPPRLGKPSEFAGLVMHILENRYLNG 240 HGIRVVTIAPGIIETPMMLGMPEEVLESLSRNVPFPPRLGKPSEFAGLVMHILENRYLNG Sbjct: 181 HGIRVVTIAPGIIETPMMLGMPEEVLESLSRNVPFPPRLGKPSEFAGLVMHILENRYLNG 240 Query: 241 EVIRMDGALRMSAK 254 EVIRMDGALRMSAK Sbjct: 241 EVIRMDGALRMSAK 254 >Q135A9.1 Q135A9_RHOPS Short-chain dehydrogenase/reductase SDR Length = 254 Score = 325 bits (832), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 161/254 (63%), Positives = 201/254 (79%) Query: 1 MAVKQGVYVVTGAASGLGAATAEQLIRGGAKVVLADVNPVAGEKMQATLGANARFVLTDV 60 M + V +VTGAASGLGAATA L+ GAKVV D+N AG ++A LG + RF+ TDV Sbjct: 1 MNISNRVVLVTGAASGLGAATARSLVAAGAKVVGLDLNAAAGAVLEADLGGSFRFLTTDV 60 Query: 61 TSETSAQEVLGVASSMGAVVGLVNCAGIAPGEKLLGKGGVHRLDSFMRALNINLVGSFNM 120 T E Q + +A +G + GLVNCAGIAPGEK++G+ G H+L SF RA++INLVG+FNM Sbjct: 61 TKEEDGQAAVKLAQELGQLSGLVNCAGIAPGEKVVGRKGPHQLASFARAISINLVGTFNM 120 Query: 121 ARLAAQHISAGPADAAGERGVIIHTASIAAFDGQMGQVAYAASKGGVVSMTLPMARELAR 180 RLAA+ + PA+ GERGVII+TAS+AAFDGQ+GQ AY+ASKGGV +MTLP+ARELA+ Sbjct: 121 IRLAAEAMIQQPANDQGERGVIINTASVAAFDGQIGQAAYSASKGGVAAMTLPVARELAQ 180 Query: 181 HGIRVVTIAPGIIETPMMLGMPEEVLESLSRNVPFPPRLGKPSEFAGLVMHILENRYLNG 240 HGIRVVTIAPGI ETPMM GMP+EV ++L ++VPFPPRLG+PSE+A LV HI+ N LNG Sbjct: 181 HGIRVVTIAPGIFETPMMAGMPQEVQDALGKSVPFPPRLGRPSEYADLVQHIIANTMLNG 240 Query: 241 EVIRMDGALRMSAK 254 EVIR+DGALRM+ + Sbjct: 241 EVIRLDGALRMAPR 254 >Q6N7F4.1 Q6N7F4_RHOPA Putative 3-hydroxyacyl-CoA dehydrogenase EC=1.1.1.35 Length = 255 Score = 323 bits (829), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 163/255 (63%), Positives = 201/255 (78%), Gaps = 1/255 (0%) Query: 1 MAVKQGVYVVTGAASGLGAATAEQLIRGGAKVVLADVNPVAGEKMQATLGANARFVLTDV 60 M + V++VTGAASGLGAATA L+ GGAKVV D+N AG K++ LGA+ RF+ TDV Sbjct: 1 MNITDRVFLVTGAASGLGAATARTLVAGGAKVVGLDLNAEAGAKLEQELGASFRFLATDV 60 Query: 61 TSETSAQEVLGVASS-MGAVVGLVNCAGIAPGEKLLGKGGVHRLDSFMRALNINLVGSFN 119 T A+ + +A G V GLVNCAG+APGEK+LG+ G H+LDSF RA+ INL+GSFN Sbjct: 61 TKAEDAEAAVKLAQDVFGHVNGLVNCAGVAPGEKVLGRNGPHKLDSFARAITINLIGSFN 120 Query: 120 MARLAAQHISAGPADAAGERGVIIHTASIAAFDGQMGQVAYAASKGGVVSMTLPMARELA 179 M RLAA+ +S DA GERGVII+TAS+AAFDGQ+GQ AY+ASKGGV +MTLP+ARELA Sbjct: 121 MIRLAAEAMSKEQPDAEGERGVIINTASVAAFDGQIGQAAYSASKGGVAAMTLPIARELA 180 Query: 180 RHGIRVVTIAPGIIETPMMLGMPEEVLESLSRNVPFPPRLGKPSEFAGLVMHILENRYLN 239 +HGIRVVTIAPGI ETPMM GMP+ V ++L ++VPFPPRLG+P+E+A LV I EN LN Sbjct: 181 QHGIRVVTIAPGIFETPMMAGMPQPVQDALGKSVPFPPRLGRPAEYAALVKAICENTMLN 240 Query: 240 GEVIRMDGALRMSAK 254 GEVIR+DGALRM+ + Sbjct: 241 GEVIRLDGALRMAPR 255 >E6VEM7.1 E6VEM7_RHOPX Short-chain dehydrogenase/reductase SDR Length = 255 Score = 323 bits (829), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 163/255 (63%), Positives = 201/255 (78%), Gaps = 1/255 (0%) Query: 1 MAVKQGVYVVTGAASGLGAATAEQLIRGGAKVVLADVNPVAGEKMQATLGANARFVLTDV 60 M + V++VTGAASGLGAATA L+ GGAKVV D+N AG K++ LGA+ RF+ TDV Sbjct: 1 MNITDRVFLVTGAASGLGAATARTLVAGGAKVVGLDLNAEAGAKLEQELGASFRFLATDV 60 Query: 61 TSETSAQEVLGVASS-MGAVVGLVNCAGIAPGEKLLGKGGVHRLDSFMRALNINLVGSFN 119 T A+ + +A G V GLVNCAG+APGEK+LG+ G H+LDSF RA+ INL+GSFN Sbjct: 61 TKAEDAEAAVKLAQDVFGHVNGLVNCAGVAPGEKVLGRNGPHKLDSFARAITINLIGSFN 120 Query: 120 MARLAAQHISAGPADAAGERGVIIHTASIAAFDGQMGQVAYAASKGGVVSMTLPMARELA 179 M RLAA+ +S DA GERGVII+TAS+AAFDGQ+GQ AY+ASKGGV +MTLP+ARELA Sbjct: 121 MIRLAAEAMSKEQPDAEGERGVIINTASVAAFDGQIGQAAYSASKGGVAAMTLPIARELA 180 Query: 180 RHGIRVVTIAPGIIETPMMLGMPEEVLESLSRNVPFPPRLGKPSEFAGLVMHILENRYLN 239 +HGIRVVTIAPGI ETPMM GMP+ V ++L ++VPFPPRLG+P+E+A LV I EN LN Sbjct: 181 QHGIRVVTIAPGIFETPMMAGMPQPVQDALGKSVPFPPRLGRPAEYAALVKAICENTMLN 240 Query: 240 GEVIRMDGALRMSAK 254 GEVIR+DGALRM+ + Sbjct: 241 GEVIRLDGALRMAPR 255 >B3QFI6.1 B3QFI6_RHOPT Short-chain dehydrogenase/reductase SDR Length = 255 Score = 323 bits (829), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 163/255 (63%), Positives = 201/255 (78%), Gaps = 1/255 (0%) Query: 1 MAVKQGVYVVTGAASGLGAATAEQLIRGGAKVVLADVNPVAGEKMQATLGANARFVLTDV 60 M + V++VTGAASGLGAATA L+ GGAKVV D+N AG K++ LGA+ RF+ TDV Sbjct: 1 MNITDRVFLVTGAASGLGAATARTLVAGGAKVVGLDLNAEAGAKLEQELGASFRFLATDV 60 Query: 61 TSETSAQEVLGVASS-MGAVVGLVNCAGIAPGEKLLGKGGVHRLDSFMRALNINLVGSFN 119 T A+ + +A G V GLVNCAG+APGEK+LG+ G H+LDSF RA+ INL+GSFN Sbjct: 61 TKAEDAEAAVKLAQDVFGHVNGLVNCAGVAPGEKVLGRNGPHKLDSFARAITINLIGSFN 120 Query: 120 MARLAAQHISAGPADAAGERGVIIHTASIAAFDGQMGQVAYAASKGGVVSMTLPMARELA 179 M RLAA+ +S DA GERGVII+TAS+AAFDGQ+GQ AY+ASKGGV +MTLP+ARELA Sbjct: 121 MIRLAAEAMSKEQPDAEGERGVIINTASVAAFDGQIGQAAYSASKGGVAAMTLPIARELA 180 Query: 180 RHGIRVVTIAPGIIETPMMLGMPEEVLESLSRNVPFPPRLGKPSEFAGLVMHILENRYLN 239 +HGIRVVTIAPGI ETPMM GMP+ V ++L ++VPFPPRLG+P+E+A LV I EN LN Sbjct: 181 QHGIRVVTIAPGIFETPMMAGMPQPVQDALGKSVPFPPRLGRPAEYAALVKAICENTMLN 240 Query: 240 GEVIRMDGALRMSAK 254 GEVIR+DGALRM+ + Sbjct: 241 GEVIRLDGALRMAPR 255 >Q1DGL1.1 Q1DGL1_AEDAE Hydroxyacyl dehydrogenase Length = 368 Score = 320 bits (821), Expect = 8e-86, Method: Compositional matrix adjust. Identities = 162/254 (63%), Positives = 202/254 (79%) Query: 1 MAVKQGVYVVTGAASGLGAATAEQLIRGGAKVVLADVNPVAGEKMQATLGANARFVLTDV 60 M +K V+VVTG SGLGAATA+ ++ G KVVLADVN AG+ + A LGA+ARFV TDV Sbjct: 115 MEIKDNVFVVTGGGSGLGAATAKMIVAAGGKVVLADVNKEAGDALAAELGASARFVATDV 174 Query: 61 TSETSAQEVLGVASSMGAVVGLVNCAGIAPGEKLLGKGGVHRLDSFMRALNINLVGSFNM 120 T E SA+ A+ +G + GLVNCAG+AP EK++G+ G HRL+SF R ++INL+GSFNM Sbjct: 175 TDEASAKACFAAATELGTLRGLVNCAGVAPAEKVVGREGPHRLESFARTVSINLIGSFNM 234 Query: 121 ARLAAQHISAGPADAAGERGVIIHTASIAAFDGQMGQVAYAASKGGVVSMTLPMARELAR 180 RLAA+ +S +A GERGVI+ TAS+AAFDGQ+GQ YAASKGGVV+MTLP+AREL R Sbjct: 235 IRLAAEIMSKNEPNAGGERGVIVSTASVAAFDGQLGQAGYAASKGGVVAMTLPIARELCR 294 Query: 181 HGIRVVTIAPGIIETPMMLGMPEEVLESLSRNVPFPPRLGKPSEFAGLVMHILENRYLNG 240 GIRV+TIAPGI+ETPM++GMP +V ESL + VPFP R+GKP+E+A LV HI N YLNG Sbjct: 295 SGIRVMTIAPGIMETPMLMGMPADVQESLGKMVPFPSRMGKPAEYAALVEHIFGNAYLNG 354 Query: 241 EVIRMDGALRMSAK 254 EVIR+DGA+RM+AK Sbjct: 355 EVIRLDGAIRMAAK 368 >C1DLN4.1 C1DLN4_AZOVD Short-chain dehydrogenase/reductase SDR Length = 254 Score = 313 bits (803), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 159/254 (62%), Positives = 192/254 (75%) Query: 1 MAVKQGVYVVTGAASGLGAATAEQLIRGGAKVVLADVNPVAGEKMQATLGANARFVLTDV 60 M + VYVV+G +SGLGAATA ++ G +VVLAD++ AG + A LG ARFV TDV Sbjct: 1 MRIGDNVYVVSGGSSGLGAATARLIVERGGRVVLADIDREAGVALAAELGERARFVETDV 60 Query: 61 TSETSAQEVLGVASSMGAVVGLVNCAGIAPGEKLLGKGGVHRLDSFMRALNINLVGSFNM 120 SA A MG + GLVNCAGIAP EKL+G+ G H L++F R L INL+GSFNM Sbjct: 61 ARADSAHACFEAAVGMGPLRGLVNCAGIAPAEKLVGRAGPHALETFARTLEINLLGSFNM 120 Query: 121 ARLAAQHISAGPADAAGERGVIIHTASIAAFDGQMGQVAYAASKGGVVSMTLPMARELAR 180 RLAA + DAAGERGVI++TAS+AAF+GQ+GQ AYAASKGGVV+MTLP+AREL + Sbjct: 121 IRLAAAIMRETEPDAAGERGVIVNTASVAAFEGQIGQAAYAASKGGVVAMTLPLARELCQ 180 Query: 181 HGIRVVTIAPGIIETPMMLGMPEEVLESLSRNVPFPPRLGKPSEFAGLVMHILENRYLNG 240 HGIRV+ IAPG++ETPM+LGMP EV SL R VPFPPRLG+P EFA LV HI N YLNG Sbjct: 181 HGIRVMCIAPGVMETPMLLGMPAEVQASLGRMVPFPPRLGRPGEFAALVEHIFANPYLNG 240 Query: 241 EVIRMDGALRMSAK 254 EVIR+DGA+RM+A+ Sbjct: 241 EVIRLDGAIRMAAR 254 >Q1BV50.1 Q1BV50_BURCA Short-chain dehydrogenase/reductase SDR Length = 255 Score = 313 bits (803), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 161/255 (63%), Positives = 194/255 (76%), Gaps = 1/255 (0%) Query: 1 MAVKQGVYVVTGAASGLGAATAEQLIRGGAKVVLADVNPVAGEKMQATLGANARFVLTDV 60 M +K V+++TGA SGLGAA A ++ G K VL DVN AG + LGA ARFV TDV Sbjct: 1 MNIKDRVFLITGAGSGLGAAVARMVVAQGGKAVLLDVNDEAGAGLANELGAAARFVKTDV 60 Query: 61 TSETSAQEVLGVASS-MGAVVGLVNCAGIAPGEKLLGKGGVHRLDSFMRALNINLVGSFN 119 TSE Q + A G V LVNCAG+APGEK++G+ G+H LD F RA++INLVG+FN Sbjct: 61 TSEADGQAAVAAARDAFGRVDALVNCAGVAPGEKVVGRDGLHSLDRFARAVSINLVGTFN 120 Query: 120 MARLAAQHISAGPADAAGERGVIIHTASIAAFDGQMGQVAYAASKGGVVSMTLPMARELA 179 M RLAA+ +S ADA GERGVII+TAS+AAFDGQ+GQ AYAASK GVV MTLP+ARELA Sbjct: 121 MIRLAAEAMSKQDADAEGERGVIINTASVAAFDGQIGQAAYAASKSGVVGMTLPIARELA 180 Query: 180 RHGIRVVTIAPGIIETPMMLGMPEEVLESLSRNVPFPPRLGKPSEFAGLVMHILENRYLN 239 R GIRVVT+APGI TPMM GMP++V ++L ++VPFPPRLG+P EFA LV HI EN LN Sbjct: 181 RFGIRVVTVAPGIFATPMMAGMPQDVQDALGKSVPFPPRLGRPEEFAALVRHIAENTMLN 240 Query: 240 GEVIRMDGALRMSAK 254 GEVIR+DGALRM+ + Sbjct: 241 GEVIRLDGALRMAPR 255 >A0KCQ0.1 A0KCQ0_BURCH Short-chain dehydrogenase/reductase SDR Length = 255 Score = 313 bits (803), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 161/255 (63%), Positives = 194/255 (76%), Gaps = 1/255 (0%) Query: 1 MAVKQGVYVVTGAASGLGAATAEQLIRGGAKVVLADVNPVAGEKMQATLGANARFVLTDV 60 M +K V+++TGA SGLGAA A ++ G K VL DVN AG + LGA ARFV TDV Sbjct: 1 MNIKDRVFLITGAGSGLGAAVARMVVAQGGKAVLLDVNDEAGAGLANELGAAARFVKTDV 60 Query: 61 TSETSAQEVLGVASS-MGAVVGLVNCAGIAPGEKLLGKGGVHRLDSFMRALNINLVGSFN 119 TSE Q + A G V LVNCAG+APGEK++G+ G+H LD F RA++INLVG+FN Sbjct: 61 TSEADGQAAVAAARDAFGRVDALVNCAGVAPGEKVVGRDGLHSLDRFARAVSINLVGTFN 120 Query: 120 MARLAAQHISAGPADAAGERGVIIHTASIAAFDGQMGQVAYAASKGGVVSMTLPMARELA 179 M RLAA+ +S ADA GERGVII+TAS+AAFDGQ+GQ AYAASK GVV MTLP+ARELA Sbjct: 121 MIRLAAEAMSKQDADAEGERGVIINTASVAAFDGQIGQAAYAASKSGVVGMTLPIARELA 180 Query: 180 RHGIRVVTIAPGIIETPMMLGMPEEVLESLSRNVPFPPRLGKPSEFAGLVMHILENRYLN 239 R GIRVVT+APGI TPMM GMP++V ++L ++VPFPPRLG+P EFA LV HI EN LN Sbjct: 181 RFGIRVVTVAPGIFATPMMAGMPQDVQDALGKSVPFPPRLGRPEEFAALVRHIAENTMLN 240 Query: 240 GEVIRMDGALRMSAK 254 GEVIR+DGALRM+ + Sbjct: 241 GEVIRLDGALRMAPR 255 >B1G822.1 B1G822_9BURK Short-chain dehydrogenase/reductase SDR Length = 285 Score = 313 bits (802), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 154/248 (62%), Positives = 194/248 (78%), Gaps = 1/248 (0%) Query: 8 YVVTGAASGLGAATAEQLIRGGAKVVLADVNPVAGEKMQATLGANARFVLTDVTSETSAQ 67 +VVTG SGLGAATA +L+ GGA+V+L D++ AG + A LGANA F DV+ SA+ Sbjct: 38 FVVTGGGSGLGAATARRLVAGGARVLLIDLDEDAGASLAAELGANAHFARADVSDSASAE 97 Query: 68 EVLG-VASSMGAVVGLVNCAGIAPGEKLLGKGGVHRLDSFMRALNINLVGSFNMARLAAQ 126 L + GA+ GL+NCAG+AP EK+LG+ G HRL+SF R + INL+G+FNM RLAA Sbjct: 98 RALAAYCETFGALHGLINCAGVAPAEKVLGREGPHRLESFARTVQINLIGAFNMVRLAAA 157 Query: 127 HISAGPADAAGERGVIIHTASIAAFDGQMGQVAYAASKGGVVSMTLPMARELARHGIRVV 186 ++ GERGVII+TAS+AAFDGQ+GQ YAASKGGVV+MTLP+ARELARHGIRV+ Sbjct: 158 CMAGNTPGTDGERGVIINTASVAAFDGQIGQAGYAASKGGVVAMTLPVARELARHGIRVL 217 Query: 187 TIAPGIIETPMMLGMPEEVLESLSRNVPFPPRLGKPSEFAGLVMHILENRYLNGEVIRMD 246 +APGI+ETPM+ GMP EV ++L + VPFPPRLG+P EFA LV+HI+EN YLNGEVIR+D Sbjct: 218 AVAPGIMETPMLKGMPTEVQDALGKMVPFPPRLGRPEEFAALVLHIVENTYLNGEVIRLD 277 Query: 247 GALRMSAK 254 GA+RM+AK Sbjct: 278 GAIRMAAK 285