BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0370.p (230 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IVA1.1 D8IVA1_HERSS 4'-phosphopantetheinyl transferase protein... 450 e-125 Q2Y7Z1.1 Q2Y7Z1_NITMU 4'-phosphopantetheinyl transferase 154 8e-36 E3HPT0.1 E3HPT0_ACHXA 4'-phosphopantetheinyl transferase superfa... 144 1e-32 C5CUF1.1 C5CUF1_VARPS 4'-phosphopantetheinyl transferase 143 2e-32 A9BM42.1 A9BM42_DELAS 4'-phosphopantetheinyl transferase 137 9e-31 B3RAB4.1 B3RAB4_CUPTR 4'-phosphopantetheinyl transferase EC=2.7.8.- 121 7e-26 B8EMK9.1 B8EMK9_METSB 4'-phosphopantetheinyl transferase 117 2e-24 E5AVC8.1 E5AVC8_BURRH 4'-phosphopantetheinyl transferase (EC 2.7... 110 2e-22 B1FU76.1 B1FU76_9BURK 4'-phosphopantetheinyl transferase 110 2e-22 B2TAK1.1 B2TAK1_BURPP 4'-phosphopantetheinyl transferase 109 3e-22 >D8IVA1.1 D8IVA1_HERSS 4'-phosphopantetheinyl transferase protein EC=2.7.8.- Length = 226 Score = 450 bits (1157), Expect = e-125, Method: Compositional matrix adjust. Identities = 224/226 (99%), Positives = 226/226 (100%) Query: 5 MPADLAACTGLPPGIEVWQYCLADIETGADAGLLAAARAQLSSAERVRMDALVRPADRRR 64 MPA+LAACTGLPPGIEVWQYCLADIETGADAGLLAAARAQLSSAERVRMDALVRPADRRR Sbjct: 1 MPAELAACTGLPPGIEVWQYCLADIETGADAGLLAAARAQLSSAERVRMDALVRPADRRR 60 Query: 65 FALAHALLRLLLARRLDCPPSRLDFMVGPFGKPRLAQCDSLHFNLSHAGDYVLLALSEQG 124 +ALAHALLRLLLARRLDCPPSRLDFMVGPFGKPRLAQCDSLHFNLSHAGDYVLLALSEQG Sbjct: 61 YALAHALLRLLLARRLDCPPSRLDFMVGPFGKPRLAQCDSLHFNLSHAGDYVLLALSEQG 120 Query: 125 EVGVDIEYRDPGLDVGSLAELAWSERERRDGQIQPCDFFARWTGKEAVLKALGVGIGEHL 184 EVGVDIEYRDPGLDVGSLAELAWSERERRDGQIQPCDFFARWTGKEAVLKALGVGIGEHL Sbjct: 121 EVGVDIEYRDPGLDVGSLAELAWSERERRDGQIQPCDFFARWTGKEAVLKALGVGIGEHL 180 Query: 185 QALSIHPRADGSYAIAHDQAGWAEVQACQLVSPPGYAAAVAWLSTP 230 QALSIHPRADGSYAIAHDQAGWAEVQACQLVSPPGYAAAVAWLSTP Sbjct: 181 QALSIHPRADGSYAIAHDQAGWAEVQACQLVSPPGYAAAVAWLSTP 226 >Q2Y7Z1.1 Q2Y7Z1_NITMU 4'-phosphopantetheinyl transferase Length = 280 Score = 154 bits (390), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 97/215 (45%), Positives = 124/215 (57%), Gaps = 8/215 (3%) Query: 15 LPPGIEVWQYCLADIETGADAGLLAAARAQLSSAERVRMDALVRPADRRRFALAHALLRL 74 +P G+EVW L +++ G + A A LS+ ER R DR R A LR Sbjct: 21 IPDGMEVW---LLELDVGL--SVPDAELALLSAEERAHAQRFRRQEDRVRSVATRAALRR 75 Query: 75 LLARRLDCPPSRLDFMVGPFGKPRLAQCDSLHFNLSHAGDYVLLALSEQGEVGVDIEYRD 134 L+ RL PP +L F+V P+GKPRL + FN+SHAG L+ALS G VGVDIE + Sbjct: 76 LVGARLMLPPDQLRFVVNPYGKPRLEGEPEIEFNVSHAGCCALIALSTSGPVGVDIECEE 135 Query: 135 PGLDVGSLAELA---WSERERRDGQIQPCDFFARWTGKEAVLKALGVGIGEHLQALSIHP 191 L+ +L ELA +S ER DF W KE+VLKALG+GI EHLQ++SI P Sbjct: 136 RVLNAKNLEELAAYVFSPLERHLALQTSKDFIQHWVAKESVLKALGLGISEHLQSVSILP 195 Query: 192 RADGSYAIAHDQAGWAEVQACQLVSPPGYAAAVAW 226 R D +Y IAHD W E+QA +L GYAAA+A+ Sbjct: 196 RDDEAYQIAHDSPEWPEIQAWRLPVSDGYAAALAF 230 >E3HPT0.1 E3HPT0_ACHXA 4'-phosphopantetheinyl transferase superfamily protein 2 Length = 232 Score = 144 bits (362), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 97/219 (44%), Positives = 121/219 (55%), Gaps = 12/219 (5%) Query: 15 LPPGIEVWQYCLADIETGADAGLLAAARAQLSSAERVRMDALVRPADRRRFALAHALLRL 74 LP GI+V+Q + A L + +A LS E R R D+ RF A A LR Sbjct: 10 LPAGIQVFQ-----LALDLAAPLADSDQALLSREEAERALRFHRHGDKVRFVSARAALRR 64 Query: 75 LLARRLDCPPSRLDFMVGPFGKPRL-AQCDS---LHFNLSHAGDYVLLALSEQGEVGVDI 130 LL+ RL+C P RL F GKPRL C + +FN+SHAG + L+ALS+ VGVDI Sbjct: 65 LLSARLNCYPGRLRFAANKHGKPRLDVACSADPAPYFNVSHAGGFALIALSDSVPVGVDI 124 Query: 131 EYRDPGLDVGSLAELAWSERERRDGQIQPCDFFARWTGKEAVLKALGVGIGEHLQALSIH 190 E RDP DV SL+ L S E + + DFF WT KEAVLKALG+G+ EHLQ LS+ Sbjct: 125 ERRDPHCDVASLSRLVLSTHELESPEERRLDFFDCWTAKEAVLKALGLGVAEHLQRLSVF 184 Query: 191 ---PRADGSYAIAHDQAGWAEVQACQLVSPPGYAAAVAW 226 P YA+ + V +L SP GYAAA+AW Sbjct: 185 GPGPAGGSCYALHRENLEGPNVDVLRLDSPSGYAAALAW 223 >C5CUF1.1 C5CUF1_VARPS 4'-phosphopantetheinyl transferase Length = 229 Score = 143 bits (360), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 95/220 (43%), Positives = 129/220 (58%), Gaps = 14/220 (6%) Query: 15 LPPGIEVWQYCLADIETGADAGLLAAARAQLSSAERVRMDALVRPADRRRFALAHALLRL 74 LP GIEV + D++ AD ++A R L+ AER + D R ADR RF A LR Sbjct: 10 LPAGIEVHRL---DLDLDAD---VSAERQLLALAERAQADRYARSADRVRFTATRAALRG 63 Query: 75 LLARRLDCPPSRLDFMVGPFGKPRL--AQCDSLHFNLSHAGDYVLLALSEQ---GEVGVD 129 LLARR+ C P+ + F GP KP L A D+ FN+SH+G + L+AL++ VG+D Sbjct: 64 LLARRVGCQPADVRFATGPHRKPFLDVAGGDAPLFNVSHSGAHALIALADPRVVSAVGID 123 Query: 130 IEYRDPGLDVGSLAELAWSERERRDGQI--QPCD-FFARWTGKEAVLKALGVGIGEHLQA 186 IE +D ++A LA++ ERR Q P ++RW GKEAVLKA+GVG+ EH Q+ Sbjct: 124 IEACRSDVDAEAVASLAFTGSERRALQEAGDPLQALYSRWVGKEAVLKAVGVGVAEHFQS 183 Query: 187 LSIHPRADGSYAIAHDQAGWAEVQACQLVSPPGYAAAVAW 226 + IHP A G Y + W+ + A L +P GYAAA+AW Sbjct: 184 IGIHPGAQGRYVLECAVPEWSGLHAVALDAPTGYAAALAW 223 >A9BM42.1 A9BM42_DELAS 4'-phosphopantetheinyl transferase Length = 229 Score = 137 bits (346), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 91/218 (41%), Positives = 125/218 (57%), Gaps = 16/218 (7%) Query: 18 GIEVWQYCLADIETGADAGLLAAARAQLSSAERVRMDALVRPADRRRFALAHALLRLLLA 77 GIEV++ D++ A+ L+ + L+ ER R VR ADR RFA A R LL Sbjct: 13 GIEVFRL---DLDLSAE---LSDSLPHLTPEERGRAARFVRAADRLRFAQTRAATRRLLG 66 Query: 78 RRLDCPPSRLDFMVGPFGKPRLAQCDSLH---FNLSHAGDYVLLALSEQGEV---GVDIE 131 RRL C P+ + VG GKP + + D L FN+SH+G + L+AL++ G V GVDIE Sbjct: 67 RRLGCCPADVPLAVGVHGKPFVDE-DPLRAPLFNVSHSGGHALIALADPGGVLHLGVDIE 125 Query: 132 YRDPGLDVGSLAELAWSERERRDGQIQP---CDFFARWTGKEAVLKALGVGIGEHLQALS 188 P LD + + +++ER + P F+ RW GKEAVLKA+G+G+ +HL+++ Sbjct: 126 QHKPDLDAEVMLDAVCTDQERASVRRAPDRLAAFYQRWVGKEAVLKAIGIGVADHLRSIG 185 Query: 189 IHPRADGSYAIAHDQAGWAEVQACQLVSPPGYAAAVAW 226 I P DG AIA W QA L +PPGYAAA+AW Sbjct: 186 ISPGGDGRLAIACAVPDWNGFQAMALPAPPGYAAALAW 223 >B3RAB4.1 B3RAB4_CUPTR 4'-phosphopantetheinyl transferase EC=2.7.8.- Length = 262 Score = 121 bits (304), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 86/204 (42%), Positives = 113/204 (55%), Gaps = 23/204 (11%) Query: 45 LSSAERVRMDALVRPADRRRFALAHALLRLLLARRLDCPPSRLDFMVGPFGKPRLAQCDS 104 L S E+ L + ADRRRF+ A LR +LA+RL C PS L F G GKP + + Sbjct: 58 LCSREQAHCATLRQAADRRRFSGARVGLRTVLAQRLGCAPSALRFRTGSHGKPYVEASGT 117 Query: 105 LHFNLSHAGDYVLLALSEQ-GEVGVDIEYRDPGLDVGSLAELAWSERERRD--------G 155 FN++HAGDY +AL+E GEVGVDIE DP L + ++ ELA R+ Sbjct: 118 AAFNVAHAGDYAWIALAEAGGEVGVDIERIDPVLGLAAMRELAAHCLTPRECAWLASLPA 177 Query: 156 QIQPCDFFARWTGKEAVLKALGVGIGEHLQALSIHPRADGS-----YAIAHD-------Q 203 P FF WT KEA+LKALG+GI +HLQ +S+ ADG+ A+ + Sbjct: 178 HAWPSSFFLLWTAKEALLKALGLGIADHLQHVSV--VADGAGGACRLAVVPEPGQLAAHA 235 Query: 204 AGWAEVQACQLVSPPGYAAAVAWL 227 A A +Q +L P GYAAA+AW+ Sbjct: 236 AALARIQLYRLAGPDGYAAAMAWV 259 >B8EMK9.1 B8EMK9_METSB 4'-phosphopantetheinyl transferase Length = 233 Score = 117 bits (292), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 84/217 (38%), Positives = 109/217 (50%), Gaps = 13/217 (5%) Query: 17 PGIEVWQYCLADIETGADAGLLAAARAQLSSAERVRMDALVRPADRRRFALAHALLRLLL 76 P ++W +E D LAAA LSS E R D R DR R L+ A LRL++ Sbjct: 20 PAAKLWL-----VEAAPDPARLAAAEPLLSSDEIQRADRFYRLEDRARAVLSRAALRLIV 74 Query: 77 ARRLDCPPSRLDFMVGPFGKPRLAQCDSLHFNLSHAGDYVLLALSEQGEVGVDIEYRDPG 136 P +L F +GPFGKP LA+ LHFN+SH+GD L+ LS + +GVDIE Sbjct: 75 GEAAGIAPEKLAFSLGPFGKPFLAERPDLHFNVSHSGDLALIGLSAERMIGVDIELMREN 134 Query: 137 LDVGSLAELAWSERERR-----DGQIQPCDFFARWTGKEAVLKALGVGIGEHLQALSIH- 190 LD LA + + E R G Q F+ WT KEAVLKA G+G+ L+ + Sbjct: 135 LDEVELARMFFCASEHRLIASKAGAAQLEAFYRIWTAKEAVLKAFGIGVAASLKDFEVRL 194 Query: 191 -PRADGSYAIAHDQA-GWAEVQACQLVSPPGYAAAVA 225 P A + +A A A VQ + +P YAA VA Sbjct: 195 SPGALAIWPLAGRLAPALAGVQIEPVAAPDSYAATVA 231 >E5AVC8.1 E5AVC8_BURRH 4'-phosphopantetheinyl transferase (EC 2.7.8.-) EC=2.7.8.- Length = 253 Score = 110 bits (275), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 80/195 (41%), Positives = 106/195 (54%), Gaps = 10/195 (5%) Query: 42 RAQLSSAERVRMDALVRPADRRRFALAHALLRLLLARRLDCPPSRLDFMVGPFGKPRL-A 100 +A LS E+ + R DR RFA A+LR LLAR P L F GPFG+P L Sbjct: 42 QAWLSDDEQQQALRYRRDEDRLRFAATRAVLRTLLARHTGGVPLSLRFSSGPFGRPELDG 101 Query: 101 QCDSLHFNLSHAGDYVLLALSEQGEVGVDIEYRDPGLDVGSLAELAWSERERR----DGQ 156 D+L FN++HAG + +ALS++ VGVDIE + LD +L ++ E+R G Sbjct: 102 YGDTLSFNVTHAGQHAFIALSDRRCVGVDIECIERVLDWQALLGTVCTDAEQRALRMSGH 161 Query: 157 IQPCD-FFARWTGKEAVLKALGVGIGEHLQALSIHPRADGSYAI-AHDQAGWAEVQACQL 214 + FF WT KEAVLKALGVGIG LQ +S+ P A G + A + W ++ A QL Sbjct: 162 VHGAHGFFRCWTAKEAVLKALGVGIGYGLQQVSVDPFAQGVQRVDAPARGAWGDITALQL 221 Query: 215 V---SPPGYAAAVAW 226 GYA +A+ Sbjct: 222 HWIDDVAGYAGCIAF 236 >B1FU76.1 B1FU76_9BURK 4'-phosphopantetheinyl transferase Length = 233 Score = 110 bits (274), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 86/223 (38%), Positives = 108/223 (48%), Gaps = 15/223 (6%) Query: 16 PPGIEVWQYCLADIETGADAGLLAAARAQLSSAERVRMDALVRPADRRRFALAHALLRLL 75 P + +W+ ++ D L AA+ A LS ER R + R D RFA A LR L Sbjct: 15 PHDLSLWR-----VDLSFDTSLDAASFASLSDDERARARSFRRAEDALRFATTRAALREL 69 Query: 76 LARRLDCPPSRLDFMVGPFGKPRLAQCDSLHFNLSHAGDYVLLALSEQGEVGVDIEYRDP 135 LA R+D L F V G+PRLA + FN+SHAG L+A+S VGVDIE Sbjct: 70 LAERIDADAHALRFTVDANGRPRLADSTAFDFNVSHAGACGLIAMSSARRVGVDIEQCSD 129 Query: 136 GLDVGSLAEL-------AWSERERRDGQIQPCDFFARWTGKEAVLKALGVGIGEHLQALS 188 D S+ L AW ER R Q+ F+ WT KEA++K GVGI LQ LS Sbjct: 130 TFDWRSIVTLTLDPHEAAWIERLDRSAQMAA--FYDAWTAKEALVKTTGVGIARGLQHLS 187 Query: 189 IHPRADGSYAIAHDQAGWAEVQACQLVSPP-GYAAAVAWLSTP 230 + PR + A Q ++ P GYAA VAW TP Sbjct: 188 VLPREGQRVTLRGPIPDDMRAIAAQWIAAPRGYAACVAWSLTP 230 >B2TAK1.1 B2TAK1_BURPP 4'-phosphopantetheinyl transferase Length = 231 Score = 109 bits (272), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 83/222 (37%), Positives = 104/222 (46%), Gaps = 13/222 (5%) Query: 16 PPGIEVWQYCLADIETGADAGLLAAARAQLSSAERVRMDALVRPADRRRFALAHALLRLL 75 P I +W+ I+ A L A A LS ER R R D RF A LR Sbjct: 14 PSDIALWR-----IDIDFTASLDAPAFVSLSDDERTRARNFRRHEDALRFVSVRAALREE 68 Query: 76 LARRLDCPPSRLDFMVGPFGKPRLAQCDSLHFNLSHAGDYVLLALSEQGEVGVDIEYRDP 135 LARRLD + F +P LA D FN+SHAG + L+A+S VGVDIE Sbjct: 69 LARRLDIAAHAMRFAPDANHRPHLADSDRFDFNVSHAGAHGLIAMSAVRRVGVDIEQCSD 128 Query: 136 GLDVGSLAELAWSER-----ERRDGQIQPCDFFARWTGKEAVLKALGVGIGEHLQALSIH 190 D S+A L + ER D + F+ W KEA++K GVGI LQ L++ Sbjct: 129 KFDWRSIAALTLDQEETAWIERLDAAQRSAAFYDAWVAKEALVKTTGVGITRGLQHLTVL 188 Query: 191 PRADGSYAIAHDQ--AGWAEVQACQLVSPPGYAAAVAWLSTP 230 PR +G+ Q A +V A L +P YAA VAW TP Sbjct: 189 PR-EGARVTLRKQIPADMRDVAAYWLAAPDAYAACVAWSVTP 229