BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0180.p (518 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IYM1.1 D8IYM1_HERSS Zn-dependent protease, containing TPR repe... 1047 0.0 A4G8A1.2 A4G8A1_HERAR Putative peptidase family M48 protein 593 e-167 F1VZU5.1 F1VZU5_9BURK Putative peptidase family M48 protein 589 e-166 A6T1Z6.1 A6T1Z6_JANMA Peptidase M48 family 588 e-166 C3X4E8.1 C3X4E8_OXAFO Peptidase M48 family 483 e-134 C3XAK4.1 C3XAK4_OXAFO Peptidase M48 family 454 e-125 Q1LR53.1 Q1LR53_RALME Zinc metalloprotease, peptidase family M48... 371 e-100 B2AHC8.1 B2AHC8_CUPTR Putative zinc metallopeptidase, putative 359 5e-97 Q0KE67.1 Q0KE67_CUPNH Zinc metalloprotease EC=3.4.24.- 357 3e-96 D8NP43.1 D8NP43_RALSO Putative zinc metallopeptidase, 344 2e-92 >D8IYM1.1 D8IYM1_HERSS Zn-dependent protease, containing TPR repeats, protein Length = 552 Score = 1047 bits (2708), Expect = 0.0, Method: Compositional matrix adjust. Identities = 516/518 (99%), Positives = 517/518 (99%) Query: 1 MQRFVPDAIACSRRPARKLITRLLSAALLLLPAAPLTLLPHPGVAQGLPTLGDTEREGLS 60 MQR+VPDAIACSRRPARKLITRLLSAALLLLPAAPLTLLPHPGVAQ LPTLGDTEREGLS Sbjct: 35 MQRYVPDAIACSRRPARKLITRLLSAALLLLPAAPLTLLPHPGVAQSLPTLGDTEREGLS 94 Query: 61 PLMERRLGEEIMRDIRSDRDYVDDGPISEYLNNFGLNLVSIHPEVRGEAGFDFQFFMVRD 120 PLMERRLGEEIMRDIRSDRDYVDDGPISEYLNNFGLNLVSIHPEVRGEAGFDFQFFMVRD Sbjct: 95 PLMERRLGEEIMRDIRSDRDYVDDGPISEYLNNFGLNLVSIHPEVRGEAGFDFQFFMVRD 154 Query: 121 PMLNAFALPGGFIGVNSGLVLAAQSESELAGVMSHEIGHVAQRHIARMLGQQKQNSMIQL 180 PMLNAFALPGGFIGVNSGLVLAAQSESELAGVMSHEIGHVAQRHIARMLGQQKQNSMIQL Sbjct: 155 PMLNAFALPGGFIGVNSGLVLAAQSESELAGVMSHEIGHVAQRHIARMLGQQKQNSMIQL 214 Query: 181 AAIVLGALAGVSKAGGDAAMATMMGGTGLAVQRQLNFSRDAEREADRIGLQIMRDGGFDP 240 AAIVLGALAGVSKAGGDAAMATMMGGTGLAVQRQLNFSRDAEREADRIGLQIMRDGGFDP Sbjct: 215 AAIVLGALAGVSKAGGDAAMATMMGGTGLAVQRQLNFSRDAEREADRIGLQIMRDGGFDP 274 Query: 241 SGMVTFFGRLQAASRNYSDAVPPYLMTHPLTTERIADIEARIRDQRYKQRVDNPEFQLVR 300 SGMVTFFGRLQAASRNYSDAVPPYLMTHPLTTERIADIEARIRDQRYKQRVDNPEFQLVR Sbjct: 275 SGMVTFFGRLQAASRNYSDAVPPYLMTHPLTTERIADIEARIRDQRYKQRVDNPEFQLVR 334 Query: 301 ARTQVLQNDTVQGLRENAEKFIAQARQNTKLQTAAAKYGLAYVYYRQNKFEQAETALKEA 360 ARTQVLQNDTVQGLRENAEKFIAQARQNTKLQTAAAKYGLAYVYYRQNKFEQAETALKEA Sbjct: 335 ARTQVLQNDTVQGLRENAEKFIAQARQNTKLQTAAAKYGLAYVYYRQNKFEQAETALKEA 394 Query: 361 QEAAIPMKTGIMFGSLDIDIKIARKQSSQAVQLADALRKQFPISRTIARQYADALIAARR 420 QEAAIPMKTGIMFGSLDIDIKIARKQSSQAVQLADALRKQFPISRTIARQYADALIAARR Sbjct: 395 QEAAIPMKTGIMFGSLDIDIKIARKQSSQAVQLADALRKQFPISRTIARQYADALIAARR 454 Query: 421 TDEAVAYLRDQAQLYRSDAQVQQLLAKAYASQGKQALQHLALAESYALNGSLLAAIDQLG 480 TDEAVAYLRDQAQLYRSDAQVQQLLAKAYASQGKQALQHLALAESYALNGSLLAAIDQLG Sbjct: 455 TDEAVAYLRDQAQLYRSDAQVQQLLAKAYASQGKQALQHLALAESYALNGSLLAAIDQLG 514 Query: 481 IARRAPDATFYDQSQIDAREREWKERWKDEQKEMKDRS 518 IARRAPDATFYDQSQIDAREREWKERWKDEQKEMKDRS Sbjct: 515 IARRAPDATFYDQSQIDAREREWKERWKDEQKEMKDRS 552 >A4G8A1.2 A4G8A1_HERAR Putative peptidase family M48 protein Length = 485 Score = 593 bits (1528), Expect = e-167, Method: Compositional matrix adjust. Identities = 302/485 (62%), Positives = 369/485 (76%), Gaps = 5/485 (1%) Query: 35 PLTLLPHPGVAQGLPTLGDTEREGLSPLMERRLGEEIMRDIRSDRDYVDDGPISEYLNNF 94 P + P AQ LP+LGDTERE LSPLMER+LGE+IMRDIR +RDY++D P+ EYLN Sbjct: 2 PPAIAPSAAFAQSLPSLGDTEREELSPLMERKLGEQIMRDIRRNRDYLNDEPLQEYLNGL 61 Query: 95 GLNLVSIHPEVRGEAGFDFQFFMVRDPMLNAFALPGGFIGVNSGLVLAAQSESELAGVMS 154 G +L+++ PE RGE +DF FF VRDPMLNAFALPGGFIGV+S LVLAAQ+ESELA VM+ Sbjct: 62 GNSLLAVRPEARGETQYDFFFFAVRDPMLNAFALPGGFIGVHSALVLAAQNESELASVMA 121 Query: 155 HEIGHVAQRHIARMLGQQKQNSMIQLAAIVLGALAGVSKAGGDAAMATMMGGTGLAVQRQ 214 HEIGHVAQRHIARMLG+QKQ+ +I LAA+VLGAL + A DA +A MMGG GLA+QRQ Sbjct: 122 HEIGHVAQRHIARMLGKQKQDMLIPLAAMVLGAL--TATASPDAGIAMMMGGQGLAIQRQ 179 Query: 215 LNFSRDAEREADRIGLQIMRDGGFDPSGMVTFFGRLQAASRNYSDAVPPYLMTHPLTTER 274 LNFSRDAEREADR+GL IMR+ GF+ SGM+ FFGRLQ ASRNY+D+ PPYL +HP+TTER Sbjct: 180 LNFSRDAEREADRVGLDIMREAGFETSGMINFFGRLQQASRNYTDSAPPYLRSHPMTTER 239 Query: 275 IADIEARIRDQRYKQRVDNPEFQLVRARTQVLQNDTVQGLRENAEKFIAQARQNTKLQTA 334 IADIEAR RDQRY+Q D+ +F L++AR +VLQ+ + QG+ + F Q +Q T+ Sbjct: 240 IADIEARTRDQRYRQHADSLDFPLIQARVKVLQDPSQQGMLDARAAFERQLQQKTRTAMI 299 Query: 335 AAKYGLAYVYYRQNKFEQAETALKEAQ---EAAIPMKTGIMFGSLDIDIKIARKQSSQAV 391 A KYGLAYV RQ ++A++ L +AQ +A P ++ SL IDIK+A Q +AV Sbjct: 300 AGKYGLAYVALRQGDAKKAQSMLNDAQATLKAGSPTARNVVLSSLAIDIKLAAHQPKEAV 359 Query: 392 QLADALRKQFPISRTIARQYADALIAARRTDEAVAYLRDQAQLYRSDAQVQQLLAKAYAS 451 + A+ R QFP+SR IA QYADAL AA R D+AV +LRDQ QLYR + Q+ LAK YA+ Sbjct: 360 EEAERARNQFPLSRGIAHQYADALFAAARYDDAVIFLRDQTQLYRHEPQLYDRLAKTYAA 419 Query: 452 QGKQALQHLALAESYALNGSLLAAIDQLGIARRAPDATFYDQSQIDAREREWKERWKDEQ 511 KQA QHLALAESYALNGSL AAIDQL IARRAPDA+FYD S IDARERE K + +E Sbjct: 420 LNKQAQQHLALAESYALNGSLPAAIDQLSIARRAPDASFYDLSIIDAREREMKAQRLEEI 479 Query: 512 KEMKD 516 ++ K+ Sbjct: 480 RQEKE 484 >F1VZU5.1 F1VZU5_9BURK Putative peptidase family M48 protein Length = 500 Score = 589 bits (1518), Expect = e-166, Method: Compositional matrix adjust. Identities = 297/476 (62%), Positives = 371/476 (77%), Gaps = 13/476 (2%) Query: 48 LPTLGDTEREGLSPLMERRLGEEIMRDIRSDRDYVDDGPISEYLNNFGLNLVSIHPEVRG 107 LP+LGD+ERE LSPL ER+LGE IMRDIR DRDY+DD P +YLNNFG L++ PE RG Sbjct: 27 LPSLGDSERESLSPLTERKLGEYIMRDIRRDRDYLDDAPTLDYLNNFGNQLLAARPEARG 86 Query: 108 EAGFDFQFFMVRDPMLNAFALPGGFIGVNSGLVLAAQSESELAGVMSHEIGHVAQRHIAR 167 EAG+DF FF VRDPMLNAFALPGGFI V+S L++AAQSESELA V++HEIGHVAQRHIAR Sbjct: 87 EAGYDFFFFAVRDPMLNAFALPGGFIAVHSALLIAAQSESELASVVAHEIGHVAQRHIAR 146 Query: 168 MLGQQKQNSMIQLAAIVLGALAGVSKAGGDAAMATMMGGTGLAVQRQLNFSRDAEREADR 227 MLGQQKQ+ +I LA +L LA +++ DA+ A ++G G+A+QRQLNFSRDAEREADR Sbjct: 147 MLGQQKQDMLIPLAGAILAVLA--ARSNTDASAALLIGSQGVALQRQLNFSRDAEREADR 204 Query: 228 IGLQIMRDGGFDPSGMVTFFGRLQAASRNYSDAVPPYLMTHPLTTERIADIEARIRDQRY 287 IGLQI+RD GF+ +GMVTFFGR+Q+AS YSD +P YL +HPLTTERIADIEARIRD RY Sbjct: 205 IGLQILRDAGFETAGMVTFFGRMQSASSGYSDYLPAYLRSHPLTTERIADIEARIRDLRY 264 Query: 288 KQRVDNPEFQLVRARTQVLQNDTVQGLRENAEKFIAQARQNTKLQTAAAKYGLAYVYYRQ 347 +Q DN +FQL+RAR +VLQ+DT QG R+ ++ + AQ Q ++ QT A KYGLA V +R+ Sbjct: 265 RQHADNVDFQLIRARMRVLQDDTSQGWRDASDIYRAQLLQQSRTQTVAGKYGLALVAFRR 324 Query: 348 NKFEQAETALKEAQEAAIPMKTGI--------MFGSLDIDIKIARKQSSQAVQLADALRK 399 ++F TAL Q+A +++G + L I++ +A ++++AV LADA RK Sbjct: 325 SEF---ATALALLQDARTALRSGAPRNGGESSVLDYLGIELLLASGKATEAVSLADAARK 381 Query: 400 QFPISRTIARQYADALIAARRTDEAVAYLRDQAQLYRSDAQVQQLLAKAYASQGKQALQH 459 +FP+SR +AR+YAD L+A RTDEA+AYLRDQAQLYR+D VQ LAK Y++QGK+ LQH Sbjct: 382 RFPLSRGLARRYADVLLAVGRTDEALAYLRDQAQLYRTDPDVQDQLAKVYSTQGKRVLQH 441 Query: 460 LALAESYALNGSLLAAIDQLGIARRAPDATFYDQSQIDAREREWKERWKDEQKEMK 515 LALAESYAL GSL AA+DQL IAR APDATFYDQ+ +DARER+ + RWK+E K Sbjct: 442 LALAESYALRGSLQAAMDQLRIARTAPDATFYDQALVDARERDLEVRWKEELANSK 497 >A6T1Z6.1 A6T1Z6_JANMA Peptidase M48 family Length = 524 Score = 588 bits (1515), Expect = e-166, Method: Compositional matrix adjust. Identities = 309/517 (59%), Positives = 378/517 (73%), Gaps = 12/517 (2%) Query: 1 MQRFVPDAIACSRRPARKLITRLLSAALLLLPAAPLTLLPHPGVAQGLPTLGDTEREGLS 60 ++ +P AI+ R + L +L L P + P AQ LP+LGDTERE LS Sbjct: 10 LKFIIPSAISLPR------LRSLTMVGVLALSTLPGMVAPSLVHAQSLPSLGDTEREALS 63 Query: 61 PLMERRLGEEIMRDIRSDRDYVDDGPISEYLNNFGLNLVSIHPEVRGEAGFDFQFFMVRD 120 PLMER+LGE+IMR+I+ +RDY+ D P+ EYLNN G +L+++ PE RGEA +DF FF VRD Sbjct: 64 PLMERKLGEQIMREIKRNRDYLSDAPLQEYLNNLGASLLTVRPEARGEAQYDFFFFAVRD 123 Query: 121 PMLNAFALPGGFIGVNSGLVLAAQSESELAGVMSHEIGHVAQRHIARMLGQQKQNSMIQL 180 PMLNAFALPGGFIGV+S LVLAAQ+ESELA VM+HEIGHVAQRHIARMLG+QKQ+ +I L Sbjct: 124 PMLNAFALPGGFIGVHSALVLAAQNESELASVMAHEIGHVAQRHIARMLGKQKQDMLIPL 183 Query: 181 AAIVLGALAGVSKAGGDAAMATMMGGTGLAVQRQLNFSRDAEREADRIGLQIMRDGGFDP 240 A+++LGALA S DA MA +MGG GLA+QRQLNFSRDAEREADR+GL IMR+ GF+ Sbjct: 184 ASMILGALAISSSP--DAGMAMIMGGQGLAIQRQLNFSRDAEREADRVGLDIMREAGFET 241 Query: 241 SGMVTFFGRLQAASRNYSDAVPPYLMTHPLTTERIADIEARIRDQRYKQRVDNPEFQLVR 300 +GM+ FFGRLQ ASRNYSD PPYL +HP+TTERIADI+AR RD RY+Q VD+ +F L++ Sbjct: 242 TGMINFFGRLQTASRNYSDNAPPYLRSHPMTTERIADIQARTRDLRYRQHVDSLDFPLIQ 301 Query: 301 ARTQVLQNDTVQGLRENAEKFIAQARQNTKLQTAAAKYGLAYVYYRQNKFEQAETALKEA 360 AR +VLQ+ QGL + F Q + T+ T A KYGLA V RQ +A++ L EA Sbjct: 302 ARVRVLQDQGHQGLLDATSSFERQLQLKTRTATVAGKYGLALVALRQGNPAKAQSLLNEA 361 Query: 361 QEA---AIPMKTGIMFGSLDIDIKIARKQSSQAVQLADALRKQFPISRTIARQYADALIA 417 + A P + SL I+IK+A Q +AVQ ADA R QFPISR IA QYADAL A Sbjct: 362 RVALNNGSPSSKSAVLSSLAIEIKLAAHQPREAVQEADAARNQFPISRGIAHQYADALYA 421 Query: 418 ARRTDEAVAYLRDQAQLYRSDAQVQQLLAKAYASQGKQALQHLALAESYALNGSLLAAID 477 A R +EA AYLRDQ QLYR + + + LAK YA+ QA QHLALAESYALNGSL AA+D Sbjct: 422 AGRYEEAAAYLRDQTQLYRQEPALYERLAKVYAALKMQAQQHLALAESYALNGSLSAALD 481 Query: 478 QLGIARRAPDATFYDQSQIDAREREWK-ERWKDEQKE 513 QL IAR+APDA+FYDQS IDARERE K +R +D ++E Sbjct: 482 QLAIARKAPDASFYDQSIIDAREREIKAQRLEDIRQE 518 >C3X4E8.1 C3X4E8_OXAFO Peptidase M48 family Length = 518 Score = 483 bits (1244), Expect = e-134, Method: Compositional matrix adjust. Identities = 253/489 (51%), Positives = 343/489 (70%), Gaps = 6/489 (1%) Query: 29 LLLPAAPLTLLPHP-GVAQG-LPTLGDTEREGLSPLMERRLGEEIMRDIRSDRDYVDDGP 86 L++P + L P AQ +P+LGDT R L+P+ E +LG+EIM +RSD YV+D Sbjct: 30 LVIPLIAVFCLQTPLATAQSDIPSLGDTARGELTPVAEYQLGKEIMVQVRSDPAYVNDPV 89 Query: 87 ISEYLNNFGLNLVSIHPEVRGEAGFDFQFFMVRDPMLNAFALPGGFIGVNSGLVLAAQSE 146 ++EYL N G LVS P++RGE DF FF +RD LNAFALPGGFIGV++GL+LA QSE Sbjct: 90 LTEYLTNLGNRLVSADPQIRGELANDFSFFAIRDATLNAFALPGGFIGVHTGLLLATQSE 149 Query: 147 SELAGVMSHEIGHVAQRHIARMLGQQKQNSMIQLAAIVLGALAGVSKAGGDAAMATMMGG 206 SELA V+SHEIGHV+QRHIARML QQ+Q+ +I +AA VL LA + AA A MMGG Sbjct: 150 SELASVLSHEIGHVSQRHIARMLSQQRQDILIPIAATVLAILAAQAGGD--AAGAVMMGG 207 Query: 207 TGLAVQRQLNFSRDAEREADRIGLQIMRDGGFDPSGMVTFFGRLQAASRNYSDAVPPYLM 266 G A+Q+Q+NF+RDAE+EADR+G I++ GFD +GM +FF R+Q A+R YSDA PYL Sbjct: 208 QGYAIQKQINFTRDAEKEADRVGFSILKGAGFDTTGMTSFFQRMQTATRTYSDAPSPYLR 267 Query: 267 THPLTTERIADIEARIRDQRYKQRVDNPEFQLVRARTQVLQNDTVQGLRENAEKFIAQAR 326 THPLT+ERIADIEAR+R + Y+Q D+ +F L+RA+ +++Q+D+ L++ A F Q + Sbjct: 268 THPLTSERIADIEARVRREPYRQHADDLDFYLMRAKARLVQDDSAPALQKAAAMFEEQIK 327 Query: 327 QNTKLQTAAAKYGLAYVYYRQNKFEQAETALKEAQEAA--IPMKTGIMFGSLDIDIKIAR 384 ++L AA YGLA + ++ + +A T L++ ++ + + SL ++I +A Sbjct: 328 SGSRLYMAAGNYGLALIALQRKEPAKARTYLQQVKKTVGEAAARQSLALDSLTVEILLAS 387 Query: 385 KQSSQAVQLADALRKQFPISRTIARQYADALIAARRTDEAVAYLRDQAQLYRSDAQVQQL 444 Q++ AV+ A A +FP SR +A QYA+AL AA+R DEA YLR Q Q+YR DA +Q+ Sbjct: 388 GQTADAVREARAATVRFPSSRALAHQYANALYAAKRYDEAAKYLRKQVQMYRDDATLQRQ 447 Query: 445 LAKAYASQGKQALQHLALAESYALNGSLLAAIDQLGIARRAPDATFYDQSQIDAREREWK 504 LAK Y +QGK+AL H+ALAESYAL+G+ AA++QL +AR+A D TFYDQS IDAREREWK Sbjct: 448 LAKVYDAQGKKALMHMALAESYALSGAYTAALEQLNLARKAGDVTFYDQSVIDAREREWK 507 Query: 505 ERWKDEQKE 513 K+ KE Sbjct: 508 AIVKENLKE 516 >C3XAK4.1 C3XAK4_OXAFO Peptidase M48 family Length = 495 Score = 454 bits (1167), Expect = e-125, Method: Compositional matrix adjust. Identities = 242/472 (51%), Positives = 324/472 (68%), Gaps = 3/472 (0%) Query: 43 GVAQGLPTLGDTEREGLSPLMERRLGEEIMRDIRSDRDYVDDGPISEYLNNFGLNLVSIH 102 G G+P++GDT R L+P+ E +LG EIM+ I+ D YV+D +SEYL+N G LVS + Sbjct: 24 GAQSGIPSMGDTARGELTPVAEYKLGREIMQQIKGDPAYVNDLVLSEYLSNLGNRLVSAN 83 Query: 103 PEVRGEAGFDFQFFMVRDPMLNAFALPGGFIGVNSGLVLAAQSESELAGVMSHEIGHVAQ 162 E RGE DF FF +RD LNAFALPGGFIGV++GL+LA QSESELA V+SHEIGHV+Q Sbjct: 84 AETRGELSNDFTFFAIRDGTLNAFALPGGFIGVHTGLLLATQSESELASVLSHEIGHVSQ 143 Query: 163 RHIARMLGQQKQNSMIQLAAIVLGALAGVSKAGGDAAMATMMGGTGLAVQRQLNFSRDAE 222 RHIARM+GQ KQ+ +I +A++VL LA + A DAA A +MGG G A+Q+Q+NF+RDAE Sbjct: 144 RHIARMMGQAKQDMLIPIASVVLAILAAQASA--DAAGAVLMGGQGYALQKQINFTRDAE 201 Query: 223 READRIGLQIMRDGGFDPSGMVTFFGRLQAASRNYSDAVPPYLMTHPLTTERIADIEARI 282 +EADR+G QI++ GFD +GM TFF R+Q A+R YSDA PYL THPLT +RIADIEAR+ Sbjct: 202 KEADRVGFQILKGAGFDTTGMTTFFQRMQTATRTYSDAPSPYLRTHPLTADRIADIEARV 261 Query: 283 RDQRYKQRVDNPEFQLVRARTQVLQNDTVQGLRENAEKFIAQARQNTKLQTAAAKYGLAY 342 R + Y+Q D+ +F LVR ++ Q+D+ L A F Q + +++Q A YGLA Sbjct: 262 RHEPYRQHADDIDFYLVRGNARIDQDDSEPALHNAATVFEEQVKSGSRIQMTAGNYGLAL 321 Query: 343 VYYRQNKFEQAETALKEAQEAA-IPMKTGIMFGSLDIDIKIARKQSSQAVQLADALRKQF 401 + + A+ L+ A+++A + SL I+I + Q+++A + A A F Sbjct: 322 IALHRKNPADAKAYLQLAKKSAGNAAAKSLALNSLSIEILLESGQAAEAAREARAAMNLF 381 Query: 402 PISRTIARQYADALIAARRTDEAVAYLRDQAQLYRSDAQVQQLLAKAYASQGKQALQHLA 461 P SR IA YA +L A++R DEA YLR QAQ YR D +Q+ LAK Y + GK+AL H+A Sbjct: 382 PSSRAIAHLYASSLYASKRYDEAAKYLRKQAQSYRDDPDLQRQLAKVYDALGKKALMHMA 441 Query: 462 LAESYALNGSLLAAIDQLGIARRAPDATFYDQSQIDAREREWKERWKDEQKE 513 LAESY L G+ AA++QL +AR++PD FYDQS IDAREREWK+ ++ KE Sbjct: 442 LAESYGLVGAYQAALEQLKMARQSPDVNFYDQSMIDAREREWKKIIRESLKE 493 >Q1LR53.1 Q1LR53_RALME Zinc metalloprotease, peptidase family M48 EC=3.4.24.- Length = 605 Score = 371 bits (953), Expect = e-100, Method: Compositional matrix adjust. Identities = 215/480 (44%), Positives = 295/480 (61%), Gaps = 14/480 (2%) Query: 48 LPTLGDTEREGLSPLMERRLGEEIMRDIRSDRDYVDDGPISEYLNNFGLNLVSI--HPEV 105 LP LGD LSP ME+RLG+ IMRDIR D DYV D +++YLN G LV + Sbjct: 124 LPDLGDPSTASLSPDMEKRLGDRIMRDIRRDPDYVSDPLMNDYLNALGYRLVQAARRQNI 183 Query: 106 RGEAG-----FDFQFFMVRDPMLNAFALPGGFIGVNSGLVLAAQSESELAGVMSHEIGHV 160 G G F+ F VRD +NAFA+PGG+IGV++GL++ +++ESELA V+ HEIGHV Sbjct: 184 SGSNGSGTFATGFELFGVRDRSINAFAMPGGYIGVHTGLLVQSETESELASVLGHEIGHV 243 Query: 161 AQRHIARMLGQQKQNSMIQLAAIVLGALAGVSKAGGDAAMATMMGGTGLAVQRQLNFSRD 220 QRHIAR + Q Q+ I LA++VL LA GDAA A MGG G AV L+FSR Sbjct: 244 MQRHIARGITNQNQSMWIALASMVLAGLAATKS--GDAAAALAMGGQGAAVANLLSFSRG 301 Query: 221 AEREADRIGLQIMRDGGFDPSGMVTFFGRLQAASRNYSDAVPPYLMTHPLTTERIADIEA 280 AEREADR+G QIM GFDP GM FF RLQ ++VP Y+ THPLT+ERIAD++ Sbjct: 302 AEREADRVGFQIMTAAGFDPQGMPDFFQRLQRVMGISDNSVPAYVRTHPLTSERIADMQD 361 Query: 281 RIRDQRYKQRVDNPEFQLVRARTQVLQNDTVQGLRENAEKFIAQARQNTK-LQTAAAKYG 339 R+ + + PE++ RAR +V+Q T +R F AQ NT ++ A YG Sbjct: 362 RVSHVPPHKIPNTPEYEFARARARVIQEPTPNDVRNVLAVFQAQVNSNTSAVRLPAVYYG 421 Query: 340 LAYVYYRQNKFEQAETALKEAQE--AAIPMKT--GIMFGSLDIDIKIARKQSSQAVQLAD 395 +A+ R +F AE AL EA+ IP T M + +++ A ++ A+ A Sbjct: 422 IAFANQRLGRFADAEKALAEARRLYGNIPGATSGSPMLDVMAVELARAEGRTQDALTQAM 481 Query: 396 ALRKQFPISRTIARQYADALIAARRTDEAVAYLRDQAQLYRSDAQVQQLLAKAYASQGKQ 455 A + FP+S A YAD L+AA + D+AVA+LR + + S ++ +LLA+AYA+QGK+ Sbjct: 482 ATMRAFPLSHAAALAYADTLVAANKLDDAVAFLRSRTREETSRSEWWELLARAYAAQGKR 541 Query: 456 ALQHLALAESYALNGSLLAAIDQLGIARRAPDATFYDQSQIDAREREWKERWKDEQKEMK 515 QH A+AE YA++GS AAI+QL IAR+A D FY S++DAR + + ++K+E+++ K Sbjct: 542 LQQHQAMAEKYAMDGSYQAAIEQLQIARKAGDGDFYTLSEVDARLHQLQLQFKEEKQDNK 601 >B2AHC8.1 B2AHC8_CUPTR Putative zinc metallopeptidase, putative Length = 619 Score = 359 bits (922), Expect = 5e-97, Method: Compositional matrix adjust. Identities = 214/484 (44%), Positives = 295/484 (60%), Gaps = 23/484 (4%) Query: 48 LPTLGDTEREGLSPLMERRLGEEIMRDIRSDRDYVDDGPISEYLNNFGLNLV------SI 101 LP LGD LSP ME+RLG+ IMRDIR D YV D +S+YLN G LV SI Sbjct: 139 LPDLGDPSTAALSPDMEKRLGDRIMRDIRRDPLYVPDPLLSDYLNALGYRLVQAARRQSI 198 Query: 102 HPEVRG---EAGFDFQFFMVRDPMLNAFALPGGFIGVNSGLVLAAQSESELAGVMSHEIG 158 G GFD F VRD +NAFALPGG+IGV++GL++ + +ESELA V+ HEIG Sbjct: 199 SGSTGGGTFATGFDL--FAVRDRSINAFALPGGYIGVHTGLLVQSDTESELASVLGHEIG 256 Query: 159 HVAQRHIARMLGQQKQNSMIQLAAIVLGALAGVSKAGGDAAMATMMGGTGLAVQRQLNFS 218 HV QRHIAR + QQ Q+ I LA++VL LA DAA A MGG G A+ QL+FS Sbjct: 257 HVMQRHIARGITQQDQSMWIALASMVLAGLAATRSP--DAAAALAMGGQGAAIANQLSFS 314 Query: 219 RDAEREADRIGLQIMRDGGFDPSGMVTFFGRLQAASRNYSDAVPPYLMTHPLTTERIADI 278 R AEREADR+G QI+ GFDP GM FF RLQ AS ++VP Y+ THPLT+ERIAD+ Sbjct: 315 RGAEREADRVGFQILTAAGFDPQGMPDFFMRLQRASGTAENSVPSYVRTHPLTSERIADM 374 Query: 279 EARIRDQRYKQRVDNPEFQLVRARTQVLQNDTVQGLRENAEKFIAQARQNTKLQTAAAKY 338 + R+ ++ + PE++ R R +V+Q + L+ Q + L+ A Y Sbjct: 375 QDRVSHASQRKVPNTPEYEFARMRARVIQEASPSDLQNLRAALRTQLAGASALRAPAVHY 434 Query: 339 GLAYVYYRQNKFEQAETALKEAQE--AAIPMKTGIMFGSLDID---IKIARKQS--SQAV 391 LA+V R ++ AE L EA+ IP G GS +D +++AR Q +A+ Sbjct: 435 ALAFVEQRLRRYPAAEQELAEARRLYGTIP---GASSGSPMLDVMAVELARAQGRVPEAL 491 Query: 392 QLADALRKQFPISRTIARQYADALIAARRTDEAVAYLRDQAQLYRSDAQVQQLLAKAYAS 451 A+A K FP+S +A YA+ LI A R +EAV +LR++ + ++ ++LA+AYA Sbjct: 492 SQANASMKAFPLSHAVAVAYAETLIGAGRHEEAVRFLRERTRQETGRSEWWEMLARAYAG 551 Query: 452 QGKQALQHLALAESYALNGSLLAAIDQLGIARRAPDATFYDQSQIDAREREWKERWKDEQ 511 QGK+ QH ALAE YA++G+ AAI+QL IAR+A D FY S++DAR + + ++++++ Sbjct: 552 QGKRLQQHQALAEKYAMDGAYQAAIEQLQIARKAGDGDFYTLSEVDARLHQLERQYREDK 611 Query: 512 KEMK 515 ++ K Sbjct: 612 QDNK 615 >Q0KE67.1 Q0KE67_CUPNH Zinc metalloprotease EC=3.4.24.- Length = 577 Score = 357 bits (916), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 211/482 (43%), Positives = 291/482 (60%), Gaps = 19/482 (3%) Query: 48 LPTLGDTEREGLSPLMERRLGEEIMRDIRSDRDYVDDGPISEYLNNFGLNLVSI--HPEV 105 LP LGD LSP ME+RLG+ IMRDIR D YV D +S+YLN G LV + Sbjct: 97 LPDLGDPSTASLSPDMEKRLGDRIMRDIRRDPLYVPDPLLSDYLNALGYRLVQAARRQNI 156 Query: 106 RGEAG-----FDFQFFMVRDPMLNAFALPGGFIGVNSGLVLAAQSESELAGVMSHEIGHV 160 G G F F VRD +NAFALPGG+IGV++GL++ + +ESELA V+ HEIGHV Sbjct: 157 SGSTGAGTFATGFDLFAVRDRSINAFALPGGYIGVHTGLLVQSDTESELASVLGHEIGHV 216 Query: 161 AQRHIARMLGQQKQNSMIQLAAIVLGALAGVSKAGGDAAMATMMGGTGLAVQRQLNFSRD 220 QRHIAR + Q Q+ I LA++VL LA DAA A MGG G A+ QL+FSR Sbjct: 217 MQRHIARGITSQDQSMWIALASMVLAGLAATRSP--DAAAALAMGGQGAAIANQLSFSRG 274 Query: 221 AEREADRIGLQIMRDGGFDPSGMVTFFGRLQAASRNYSDAVPPYLMTHPLTTERIADIEA 280 AEREADR+G QI+ GFDP GM FF RLQ AS ++VP Y+ THPLT+ERIAD++ Sbjct: 275 AEREADRVGFQILTAAGFDPHGMPDFFMRLQRASGTAENSVPSYVRTHPLTSERIADMQD 334 Query: 281 RIRDQRYKQRVDNPEFQLVRARTQVLQNDTVQGLRENAEKFIAQARQNTKLQTAAAKYGL 340 R+ ++ + PE++ R R +V+Q + L+ Q T L+ A YGL Sbjct: 335 RVSHASKRKVANTPEYECARMRARVIQESSPSDLQNLRAALRTQLPGATALRAPALHYGL 394 Query: 341 AYVYYRQNKFEQAETALKEAQE--AAIPMKTGIMFGSLDID---IKIARKQS--SQAVQL 393 A+ R ++ AE L EA+ IP G GS +D +++AR Q +A+ Sbjct: 395 AFTEQRLGRYPAAEQELAEARRLYGNIP---GASSGSPMLDVMAVELARAQGRVPEALSQ 451 Query: 394 ADALRKQFPISRTIARQYADALIAARRTDEAVAYLRDQAQLYRSDAQVQQLLAKAYASQG 453 A A K F +S +A YAD L+ + R +EAV +LR++ + S ++ +LLA+AYA QG Sbjct: 452 ASASMKAFALSHAVAIAYADTLVGSGRYEEAVRFLRERTRQETSRSEWWELLARAYAGQG 511 Query: 454 KQALQHLALAESYALNGSLLAAIDQLGIARRAPDATFYDQSQIDAREREWKERWKDEQKE 513 K+ QH ALAE YA++G+ AAI+QL IAR+A D FY S++DAR + + ++++++++ Sbjct: 512 KRLQQHQALAEKYAMDGAYQAAIEQLQIARKAGDGDFYTLSEVDARLHQLERQYREDKQD 571 Query: 514 MK 515 K Sbjct: 572 SK 573 >D8NP43.1 D8NP43_RALSO Putative zinc metallopeptidase, Length = 558 Score = 344 bits (883), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 211/482 (43%), Positives = 285/482 (59%), Gaps = 19/482 (3%) Query: 48 LPTLGDTEREGLSPLMERRLGEEIMRDIRSDRDYVDDGPISEYLNNFGLNLVSI--HPEV 105 LP +GD LSP MERRLG+ +MR IR D DYV D +S+YLN+ G L+ V Sbjct: 78 LPDMGDPSTAALSPEMERRLGDRVMRQIRRDPDYVPDPLLSDYLNDIGYRLIESARRQHV 137 Query: 106 RGE-AGFDFQFFMVRDPMLNAFALPGGFIGVNSGLVLAAQSESELAGVMSHEIGHVAQRH 164 G + F+ F VRDP +NAFALPGG+IGVN+G ++A SESELA V+ HEIGHV QRH Sbjct: 138 AGSTSASSFELFAVRDPGINAFALPGGYIGVNTGTLVATDSESELASVLGHEIGHVLQRH 197 Query: 165 IARMLGQQKQNSMIQLAAIVLGALAGVSKAGGDAAMATMMGGTGLAVQRQLNFSRDAERE 224 IAR + + ++ I LA+I+L LA GDAA A +GG AV QL FSR AERE Sbjct: 198 IARGIDKSGESMWIALASILLAGLAATKS--GDAAQALAVGGQAAAVSNQLAFSRGAERE 255 Query: 225 ADRIGLQIMRDGGFDPSGMVTFFGRLQ-AASRNYSDAVPPYLMTHPLTTERIADIEARIR 283 ADR+G ++ G++P GM FF RLQ S + VP Y THPLT ERIAD+E R R Sbjct: 256 ADRVGFTLLTGAGYNPDGMPDFFRRLQRVTSIADTGIVPGYARTHPLTGERIADMEDRAR 315 Query: 284 DQRYKQRVDNPEFQLVRARTQVLQNDTVQG---LRENAEKFIAQARQNTKLQTAAAKYGL 340 + + PEF +AR +VLQ + +R +A A + AA YG+ Sbjct: 316 GLPHPLQPHRPEFGFAKARARVLQETSTSAYLDVRNAMRSQLASAPDAPVEKRAALWYGI 375 Query: 341 AYVYYRQNKFEQAETALKEAQE--AAIPMKTGIMFGSLDID---IKIARKQS--SQAVQL 393 A + + E AL EA+ IP GI GS ++D I++AR + QA+ + Sbjct: 376 AVAEQMAGQLDAPEQALLEARRLYGNIP---GITSGSPNLDVTAIELARAHNRVPQALTM 432 Query: 394 ADALRKQFPISRTIARQYADALIAARRTDEAVAYLRDQAQLYRSDAQVQQLLAKAYASQG 453 A A +P+SR + YA L+AA R D+A+ YLRD+A+ + +LLA AYA QG Sbjct: 433 ARAALTAYPMSRAVGITYAQTLLAAGRVDDAIPYLRDKAREDTAQPIWWELLAHAYADQG 492 Query: 454 KQALQHLALAESYALNGSLLAAIDQLGIARRAPDATFYDQSQIDAREREWKERWKDEQKE 513 K+ QH ALAE YA +G+ AA++QL +AR A DA FY S++DAR + + ++++E++E Sbjct: 493 KRVEQHRALAEKYARDGAWGAAVEQLKLARDAGDADFYTLSEVDARLHQMERQYREEKQE 552 Query: 514 MK 515 K Sbjct: 553 EK 554