BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0127.p (244 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IYG9.1 D8IYG9_HERSS Phosphatase (HAD superfamily) 481 e-134 F1VUS4.1 F1VUS4_9BURK 2-haloalkanoic acid dehalogenase 288 4e-76 A4G8D8.1 A4G8D8_HERAR Putative hydrolase EC=3.8.1.2 268 7e-70 A6T231.1 A6T231_JANMA Hydrolase 261 9e-68 D2UBS2.1 D2UBS2_XANAP Putative hydrolase protein 174 1e-41 E6WWH6.1 E6WWH6_PSEUU HAD-superfamily hydrolase, subfamily IA, v... 173 2e-41 B8L9X5.1 B8L9X5_9GAMM Hydrolase 172 5e-41 Q8PFJ5.1 Q8PFJ5_XANAC Hydrolase 169 4e-40 Q3BN53.1 Q3BN53_XANC5 Putative hydrolase 169 4e-40 F0BTC2.1 F0BTC2_9XANT Haloacid dehalogenase superfamily enzyme, ... 169 4e-40 >D8IYG9.1 D8IYG9_HERSS Phosphatase (HAD superfamily) Length = 244 Score = 481 bits (1239), Expect = e-134, Method: Compositional matrix adjust. Identities = 240/244 (98%), Positives = 241/244 (98%) Query: 1 MKPSASTLPASSAASPIQAVLFDLDDTLWAIEPVLVRAETLLYDWLRQHAPAVAAAHTIA 60 MKPSASTLPAS AASPIQAVLFDLDDTLWAIEPVLVRAETLLYDWLRQHAPAVAAAHTIA Sbjct: 1 MKPSASTLPASPAASPIQAVLFDLDDTLWAIEPVLVRAETLLYDWLRQHAPAVAAAHTIA 60 Query: 61 SLRERRLALMQTDPAYRINLWKLRHTALSEVFREHDVDLALVDPAMALFSEARSTVALFD 120 SLRERR+ALMQTDPAYRINLWKLRHTALSEVFREHDVDLALVDPAMALFSEARSTVALFD Sbjct: 61 SLRERRMALMQTDPAYRINLWKLRHTALSEVFREHDVDLALVDPAMALFSEARSTVALFD 120 Query: 121 DVEPALLRLKGKLTLGSVSNGFADLERIGLAGHFGVSIAAHRFGRAKPDPAIFHAACEAL 180 DVEPALLRLKGKLTLGSVSNGFADLERIGLAGHFGVSIAAHRFGRAKPDPAIFHAACEAL Sbjct: 121 DVEPALLRLKGKLTLGSVSNGFADLERIGLAGHFGVSIAAHRFGRAKPDPAIFHAACEAL 180 Query: 181 QVAPGATVYVGDDPLLDVQGAQQAGLKAVWMNRFGRVLPEGIRPDAVCRDLHELHDWLEA 240 QVAPGATVYVGDDPLLDVQGAQQAGLKAVWMNRFGRVLPE IRPDAVCRDLHELHDWLEA Sbjct: 181 QVAPGATVYVGDDPLLDVQGAQQAGLKAVWMNRFGRVLPEDIRPDAVCRDLHELHDWLEA 240 Query: 241 QCAA 244 Q AA Sbjct: 241 QSAA 244 >F1VUS4.1 F1VUS4_9BURK 2-haloalkanoic acid dehalogenase Length = 240 Score = 288 bits (737), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 142/224 (63%), Positives = 170/224 (75%) Query: 15 SPIQAVLFDLDDTLWAIEPVLVRAETLLYDWLRQHAPAVAAAHTIASLRERRLALMQTDP 74 +PI+AVLFDLDDTLW I P ++RAETLL+DWLR+HAPAV HTI +LR RR+ALM+ +P Sbjct: 4 APIKAVLFDLDDTLWPIVPTIIRAETLLFDWLREHAPAVTQDHTIDTLRARRMALMEAEP 63 Query: 75 AYRINLWKLRHTALSEVFREHDVDLALVDPAMALFSEARSTVALFDDVEPALLRLKGKLT 134 YRI+L LRH L+E F D ++ AMA+F++AR+ V +DDV P+L RL +L Sbjct: 64 RYRIDLPGLRHAGLTEAFHTSGADPVHINGAMAVFNDARNAVIPYDDVLPSLARLGRQLA 123 Query: 135 LGSVSNGFADLERIGLAGHFGVSIAAHRFGRAKPDPAIFHAACEALQVAPGATVYVGDDP 194 LG++SNG ADL IG+AGHF +SIAAH+FG AKPDPAIF AAC AL V P VYVGDDP Sbjct: 124 LGTISNGSADLSVIGMAGHFRISIAAHQFGSAKPDPAIFQAACTALDVDPAEAVYVGDDP 183 Query: 195 LLDVQGAQQAGLKAVWMNRFGRVLPEGIRPDAVCRDLHELHDWL 238 LLDV GAQ+AGL+AVWMNRF RVLP IRPDA C L EL WL Sbjct: 184 LLDVDGAQKAGLRAVWMNRFDRVLPAHIRPDASCTSLLELEHWL 227 >A4G8D8.1 A4G8D8_HERAR Putative hydrolase EC=3.8.1.2 Length = 234 Score = 268 bits (684), Expect = 7e-70, Method: Compositional matrix adjust. Identities = 134/232 (57%), Positives = 160/232 (68%) Query: 8 LPASSAASPIQAVLFDLDDTLWAIEPVLVRAETLLYDWLRQHAPAVAAAHTIASLRERRL 67 +P + S ++AVLFDLDDTLW + P L +AE +LYDWL H P V + A LRE R+ Sbjct: 1 MPTLAHPSSVKAVLFDLDDTLWPLAPTLFKAEAVLYDWLALHIPGVTRRFSNAELRELRM 60 Query: 68 ALMQTDPAYRINLWKLRHTALSEVFREHDVDLALVDPAMALFSEARSTVALFDDVEPALL 127 L+ TDP Y+ N+W LRH AL+ R + LVD AMA+FSEAR+ V FDDV P L Sbjct: 61 ELLPTDPQYQFNVWALRHAALTHACRLSSENHELVDQAMAVFSEARNAVTPFDDVVPGLA 120 Query: 128 RLKGKLTLGSVSNGFADLERIGLAGHFGVSIAAHRFGRAKPDPAIFHAACEALQVAPGAT 187 RL + +GSVSNGFADL IG++ HF SIAAH+FG AKP P IF AAC+AL +AP Sbjct: 121 RLNERFRVGSVSNGFADLSAIGISRHFQYSIAAHQFGSAKPHPEIFLAACDALSIAPHEA 180 Query: 188 VYVGDDPLLDVQGAQQAGLKAVWMNRFGRVLPEGIRPDAVCRDLHELHDWLE 239 VYVGDDPLLD+QGAQ AGL+AVWMNRF R LPE I P A LHEL WL+ Sbjct: 181 VYVGDDPLLDIQGAQNAGLQAVWMNRFQRTLPEHIVPAASVTTLHELEAWLK 232 >A6T231.1 A6T231_JANMA Hydrolase Length = 238 Score = 261 bits (666), Expect = 9e-68, Method: Compositional matrix adjust. Identities = 132/228 (57%), Positives = 155/228 (67%) Query: 12 SAASPIQAVLFDLDDTLWAIEPVLVRAETLLYDWLRQHAPAVAAAHTIASLRERRLALMQ 71 S PI+AVLFDLDDTLW + P LVRAE +LYDWL H P V + LRE R+ L+ Sbjct: 9 SPHHPIKAVLFDLDDTLWHLAPTLVRAEAILYDWLNIHIPGVTQRFSNEELRELRMELLP 68 Query: 72 TDPAYRINLWKLRHTALSEVFREHDVDLALVDPAMALFSEARSTVALFDDVEPALLRLKG 131 TDP ++ N+W LRH AL+ + LVD AMA+FS AR+ V FDDV P L L Sbjct: 69 TDPQFQFNVWALRHAALTRACHLTSENKDLVDQAMAVFSVARNAVQPFDDVAPVLGSLNE 128 Query: 132 KLTLGSVSNGFADLERIGLAGHFGVSIAAHRFGRAKPDPAIFHAACEALQVAPGATVYVG 191 + +GSVSNGFADL IGLA HF VSIAAH+FG AKP IFHAAC AL V P +YVG Sbjct: 129 RYKVGSVSNGFADLGEIGLAPHFKVSIAAHQFGSAKPGAEIFHAACAALAVEPHEAIYVG 188 Query: 192 DDPLLDVQGAQQAGLKAVWMNRFGRVLPEGIRPDAVCRDLHELHDWLE 239 DDP LD+QGAQ AGL+AVWMNRF LP+ I PDA C +L+EL WL+ Sbjct: 189 DDPKLDIQGAQNAGLRAVWMNRFKHTLPDHIVPDASCTNLYELDAWLK 236 >D2UBS2.1 D2UBS2_XANAP Putative hydrolase protein Length = 241 Score = 174 bits (441), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 95/229 (41%), Positives = 130/229 (56%) Query: 11 SSAASPIQAVLFDLDDTLWAIEPVLVRAETLLYDWLRQHAPAVAAAHTIASLRERRLALM 70 SS PI+A+ DLDDTLW P+ R E +L+DWL QH+P AA I ++R+ R ++ Sbjct: 3 SSPTFPIRAITLDLDDTLWPFAPIGARIEQVLHDWLLQHSPRTAACFPIPAMRQLRDTVV 62 Query: 71 QTDPAYRINLWKLRHTALSEVFREHDVDLALVDPAMALFSEARSTVALFDDVEPALLRLK 130 P R ++ +LR L + RE D L +PA A+F AR+ V F D PAL R+ Sbjct: 63 AAHPHLRHDMSELRRLTLRQALRESGADETLAEPAYAVFHAARNQVECFPDSLPALQRIA 122 Query: 131 GKLTLGSVSNGFADLERIGLAGHFGVSIAAHRFGRAKPDPAIFHAACEALQVAPGATVYV 190 + + ++SNG ADL IGL +F ++A G AKPDP+IF AAC L + ++V Sbjct: 123 ACMPVAALSNGNADLATIGLERYFAFQLSAGEHGAAKPDPSIFQAACARLALPCAQVLHV 182 Query: 191 GDDPLLDVQGAQQAGLKAVWMNRFGRVLPEGIRPDAVCRDLHELHDWLE 239 GD +DV GA QAGL+ W+NR G++ PD L L DWLE Sbjct: 183 GDHIEIDVVGAMQAGLRGCWINREGQLWDRPTPPDLQFDTLTGLADWLE 231 >E6WWH6.1 E6WWH6_PSEUU HAD-superfamily hydrolase, subfamily IA, variant 1 Length = 236 Score = 173 bits (438), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 94/230 (40%), Positives = 134/230 (58%), Gaps = 3/230 (1%) Query: 17 IQAVLFDLDDTLWAIEPVLVRAETLLYDWLRQHAPAVAAAHTIASLRERRLALMQTDPAY 76 ++A+ DLDDTLW P+ R + +LY+W+ +H+PA AA + +A++RE R + +P Sbjct: 8 VRAITLDLDDTLWPFAPIGARIDQVLYEWMLEHSPATAAMYPVAAMRELRERSFRDNPHL 67 Query: 77 RINLWKLRHTALSEVFREHDVDLALVDPAMALFSEARSTVALFDDVEPALLRLKGKLTLG 136 +L LR AL+E + L++PA F AR+ V + D AL R+ K+ + Sbjct: 68 HHDLSALRRLALAEALEASGASMDLLEPAYEAFYAARNQVEFYPDAVDALARIAAKVPVA 127 Query: 137 SVSNGFADLERIGLAGHFGVSIAAHRFGRAKPDPAIFHAACEALQVAPGATVYVGDDPLL 196 +VSNG ADL+RIGL HF + + G AKP P+IFHAACE L G ++VGD + Sbjct: 128 AVSNGNADLDRIGLMQHFAFQLGSREHGYAKPHPSIFHAACERLGCGHGDVLHVGDHMEM 187 Query: 197 DVQGAQQAGLKAVWMNRFGRVL--PEGIRPDAVCRDLHELHDWLEAQCAA 244 DV GA +AGL++ W+NR G PE + PD L L DWL+A AA Sbjct: 188 DVAGAARAGLRSCWINRTGETWSHPE-LEPDLEFDTLTALADWLDAHLAA 236 >B8L9X5.1 B8L9X5_9GAMM Hydrolase Length = 239 Score = 172 bits (435), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 93/227 (40%), Positives = 130/227 (57%), Gaps = 1/227 (0%) Query: 16 PIQAVLFDLDDTLWAIEPVLVRAETLLYDWLRQHAPAVAAAHTIASLRERRLALMQTDPA 75 P+QA+ DLDDTLW P+ R + +L++W+R+H+PA AA + +A++RE R L P Sbjct: 4 PVQAITLDLDDTLWPFAPIGARIDLVLHEWMREHSPATAAMYPVAAMRELRERLYHAHPH 63 Query: 76 YRINLWKLRHTALSEVFREHDVDLALVDPAMALFSEARSTVALFDDVEPALLRLKGKLTL 135 +L LR L E L L++PA +F AR+ V + D AL R+ ++ + Sbjct: 64 LHHDLSALRRLTLHEALHGSGASLDLLEPAYEVFYAARNQVECYPDAIEALARIAARVPV 123 Query: 136 GSVSNGFADLERIGLAGHFGVSIAAHRFGRAKPDPAIFHAACEALQVAPGATVYVGDDPL 195 ++SNG ADLERIGLA HF + A G AKP+ +IFHAAC L VAP ++VGD Sbjct: 124 AALSNGNADLERIGLAHHFAFQLGAREHGAAKPEASIFHAACARLGVAPAQVLHVGDHAE 183 Query: 196 LDVQGAQQAGLKAVWMNRFGRVLPE-GIRPDAVCRDLHELHDWLEAQ 241 +DV GA AGL+ W+NR ++PD L L DWL+A Sbjct: 184 MDVAGAIAAGLRGCWINREAATWTHPQLQPDLQFDTLTGLADWLDAN 230 >Q8PFJ5.1 Q8PFJ5_XANAC Hydrolase Length = 245 Score = 169 bits (428), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 93/226 (41%), Positives = 129/226 (57%), Gaps = 1/226 (0%) Query: 17 IQAVLFDLDDTLWAIEPVLVRAETLLYDWLRQHAPAVAAAHTIASLRERRLALMQTDPAY 76 I+A+ DLDDTLW P+ R + +LYDW+R+H+P A + ++RE R +P Sbjct: 5 IRAITLDLDDTLWPFAPIGARIDQVLYDWMREHSPLTAERFPVEAMRELRERSFVDNPHL 64 Query: 77 RINLWKLRHTALSEVFREHDVDLALVDPAMALFSEARSTVALFDDVEPALLRLKGKLTLG 136 +L LR L RE DLAL++PA +F AR+ V + D AL R+ + + Sbjct: 65 HHDLSALRRLTLEMALRESGGDLALLEPAYEVFYAARNQVECYPDALDALARIAAHVPVA 124 Query: 137 SVSNGFADLERIGLAGHFGVSIAAHRFGRAKPDPAIFHAACEALQVAPGATVYVGDDPLL 196 ++SNG ADL+RIGL HF + + G AKPDP+IF AAC L+V P ++VGD + Sbjct: 125 ALSNGNADLQRIGLMHHFAFQLGSREHGSAKPDPSIFLAACARLEVPPAQVLHVGDHVRM 184 Query: 197 DVQGAQQAGLKAVWMNRFGRVLPEGI-RPDAVCRDLHELHDWLEAQ 241 DV GA AGL+A W+NR G V +PD + L DWL+AQ Sbjct: 185 DVLGALDAGLRACWINREGAVWSHPTQQPDLQFDSMTGLADWLDAQ 230 >Q3BN53.1 Q3BN53_XANC5 Putative hydrolase Length = 245 Score = 169 bits (427), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 92/226 (40%), Positives = 129/226 (57%), Gaps = 1/226 (0%) Query: 17 IQAVLFDLDDTLWAIEPVLVRAETLLYDWLRQHAPAVAAAHTIASLRERRLALMQTDPAY 76 I+A+ DLDDTLW P+ R + +LYDW+R+H+P A + ++R+ R +P Sbjct: 5 IRAITLDLDDTLWPFAPIGARIDQVLYDWMREHSPVTAERFPVEAMRQLRERSFADNPHL 64 Query: 77 RINLWKLRHTALSEVFREHDVDLALVDPAMALFSEARSTVALFDDVEPALLRLKGKLTLG 136 +L LR L RE DLAL++PA +F AR+ V + D AL R+ + + Sbjct: 65 HHDLSALRRLTLEMALRESGGDLALLEPAYEVFYAARNQVECYPDALDALARIAAHVPVA 124 Query: 137 SVSNGFADLERIGLAGHFGVSIAAHRFGRAKPDPAIFHAACEALQVAPGATVYVGDDPLL 196 ++SNG ADL+RIGL HF + + G AKPDP+IF AAC L+V P ++VGD + Sbjct: 125 ALSNGNADLQRIGLMHHFAFQLGSREHGSAKPDPSIFLAACARLEVPPSEVLHVGDHVRM 184 Query: 197 DVQGAQQAGLKAVWMNRFGRVLPEGI-RPDAVCRDLHELHDWLEAQ 241 DV GA AGL+A W+NR G V +PD + L DWL+AQ Sbjct: 185 DVLGALDAGLRACWINREGAVWSHPTQQPDLEFDSMTGLADWLDAQ 230 >F0BTC2.1 F0BTC2_9XANT Haloacid dehalogenase superfamily enzyme, subfamily IA Length = 245 Score = 169 bits (427), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 92/226 (40%), Positives = 129/226 (57%), Gaps = 1/226 (0%) Query: 17 IQAVLFDLDDTLWAIEPVLVRAETLLYDWLRQHAPAVAAAHTIASLRERRLALMQTDPAY 76 I+A+ DLDDTLW P+ R + +LYDW+R+H+P A + ++R+ R +P Sbjct: 5 IRAITLDLDDTLWPFAPIGARIDQVLYDWMREHSPVTAERFPVEAMRQLRERSFADNPHL 64 Query: 77 RINLWKLRHTALSEVFREHDVDLALVDPAMALFSEARSTVALFDDVEPALLRLKGKLTLG 136 +L LR L RE DLAL++PA +F AR+ V + D AL R+ + + Sbjct: 65 HHDLSALRRLTLEMALRESGGDLALLEPAYEVFYAARNQVECYPDALDALARIAAHVPVA 124 Query: 137 SVSNGFADLERIGLAGHFGVSIAAHRFGRAKPDPAIFHAACEALQVAPGATVYVGDDPLL 196 ++SNG ADL+RIGL HF + + G AKPDP+IF AAC L+V P ++VGD + Sbjct: 125 ALSNGNADLQRIGLMHHFAFQLGSREHGSAKPDPSIFLAACARLEVPPSEVLHVGDHVRM 184 Query: 197 DVQGAQQAGLKAVWMNRFGRVLPEGI-RPDAVCRDLHELHDWLEAQ 241 DV GA AGL+A W+NR G V +PD + L DWL+AQ Sbjct: 185 DVLGALDAGLRACWINREGAVWSHPTQQPDLEFDSMTGLADWLDAQ 230