BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0072.p (309 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IYB0.1 D8IYB0_HERSS Divalent heavy-metal cations transporter p... 592 e-167 E6V821.1 E6V821_VARPD Zinc/iron permease 245 8e-63 A1TQJ7.1 A1TQJ7_ACIAC Zinc/iron permease 244 8e-63 E6V0M2.1 E6V0M2_VARPD Zinc/iron permease 228 1e-57 Q7W0E6.1 Q7W0E6_BORPE Probable metal transporter 224 1e-56 Q5P1X3.1 Q5P1X3_AROAE Probable metal transporter 223 2e-56 B3PBP4.1 B3PBP4_CELJU GufA protein 223 4e-56 F0Q0P9.1 F0Q0P9_ACIAP Zinc/iron permease 222 7e-56 Q7WP32.1 Q7WP32_BORBR Probable metal transporter 221 1e-55 Q5R117.1 Q5R117_IDILO ZIP family metal transporter 216 5e-54 >D8IYB0.1 D8IYB0_HERSS Divalent heavy-metal cations transporter protein Length = 309 Score = 592 bits (1527), Expect = e-167, Method: Compositional matrix adjust. Identities = 307/309 (99%), Positives = 307/309 (99%) Query: 1 MFEDFKPSASSAATSAAMAAPAGAAGLAAEHRMPIRWPMVALALTLACAAMGWWSVRDPR 60 MFEDFKPSASSAATSAAMAAPAGAAGLAAEHRMPIRWPMVALALTLACAAMGWWSVRDPR Sbjct: 1 MFEDFKPSASSAATSAAMAAPAGAAGLAAEHRMPIRWPMVALALTLACAAMGWWSVRDPR 60 Query: 61 IWHAYCGGMAAAAAPGAGTLPLFFSRRFSARMADCCTGFGAGVMLAASVFSLILPALQSV 120 IWHAYCGGMAAAAA AGTLPLFFSRRFSARMADCCTGFGAGVMLAASVFSLILPALQSV Sbjct: 61 IWHAYCGGMAAAAATAAGTLPLFFSRRFSARMADCCTGFGAGVMLAASVFSLILPALQSV 120 Query: 121 RTAGMGQGQASLVIGASVVAGALLVLLLQRAGQGHDDAARQAALRRVWLFVLTVGLHNLP 180 RTAGMGQGQASLVIGASVVAGALLVLLLQRAGQGHDDAARQAALRRVWLFVLTVGLHNLP Sbjct: 121 RTAGMGQGQASLVIGASVVAGALLVLLLQRAGQGHDDAARQAALRRVWLFVLTVGLHNLP 180 Query: 181 EGLAVGVAYGGVPAEQASVLTFGIALQDIPEGMIVATALRGIGYSRADAIGCGILSGLVE 240 EGLAVGVAYGGVPAEQASVLTFGIALQDIPEGMIVATALRGIGYSRADAIGCGILSGLVE Sbjct: 181 EGLAVGVAYGGVPAEQASVLTFGIALQDIPEGMIVATALRGIGYSRADAIGCGILSGLVE 240 Query: 241 PLAAVAGAAVVALSSALLPWALGGAAGAMLFVLAHEVIPDPHRRHDALAATCCLIAGFVL 300 PLAAVAGAAVVALSSALLPWALGGAAGAMLFVLAHEVIPDPHRRHDALAATCCLIAGFVL Sbjct: 241 PLAAVAGAAVVALSSALLPWALGGAAGAMLFVLAHEVIPDPHRRHDALAATCCLIAGFVL 300 Query: 301 MMVLDTALS 309 MMVLDTALS Sbjct: 301 MMVLDTALS 309 >E6V821.1 E6V821_VARPD Zinc/iron permease Length = 299 Score = 245 bits (625), Expect = 8e-63, Method: Compositional matrix adjust. Identities = 135/251 (53%), Positives = 177/251 (70%), Gaps = 7/251 (2%) Query: 64 AYCGGMAAAAAPGAGTLPLFFSRRFSARMADCCTGFGAGVMLAASVFSLILPALQSVRTA 123 A GG AA A GT+P+ S++FS R D GFGAGVMLAAS FSL++PAL + ++ Sbjct: 49 ALTGGCIAALATALGTVPVLLSQQFSQRAYDSMLGFGAGVMLAASSFSLVIPALAAAKSQ 108 Query: 124 GMGQGQASLVIGASVVAGALLVLLLQRAGQGHD------DAARQAALRRVWLFVLTVGLH 177 G G + ++G V+ GA+++L + RA H+ + AL+RVWLFVL + LH Sbjct: 109 GAGAWGSGTLVGGGVLLGAMVLLAIDRA-VPHEHFVKGLEGPESRALKRVWLFVLAIVLH 167 Query: 178 NLPEGLAVGVAYGGVPAEQASVLTFGIALQDIPEGMIVATALRGIGYSRADAIGCGILSG 237 NLPEGLA+GVA+ G A A+ LT GI++QD+PEG++VA ALR +GY + A+G G+LSG Sbjct: 168 NLPEGLAIGVAFAGTDAVGATALTTGISIQDVPEGLVVALALRSVGYGKLTAVGLGVLSG 227 Query: 238 LVEPLAAVAGAAVVALSSALLPWALGGAAGAMLFVLAHEVIPDPHRRHDALAATCCLIAG 297 LVEPLAAV GAAV+ L++ALLPW L AAGAMLFV++HE+IP+ HR+ AT L+ G Sbjct: 228 LVEPLAAVLGAAVIGLTAALLPWGLAMAAGAMLFVISHEIIPESHRKGHEAHATTGLMLG 287 Query: 298 FVLMMVLDTAL 308 FVLMMVLDTAL Sbjct: 288 FVLMMVLDTAL 298 >A1TQJ7.1 A1TQJ7_ACIAC Zinc/iron permease Length = 300 Score = 244 bits (624), Expect = 8e-63, Method: Compositional matrix adjust. Identities = 138/257 (53%), Positives = 176/257 (68%), Gaps = 6/257 (2%) Query: 58 DPRIWHAYCGGMAAAAAPGAGTLPLFFSRRFSARMADCCTGFGAGVMLAASVFSLILPAL 117 +PR+ A+ GG+ AA A GTLP+ FS+R S R+ D GFGAGVMLAAS FSLI+P L Sbjct: 43 NPRVAQAWQGGLVAALATALGTLPVVFSQRLSERVQDTLFGFGAGVMLAASSFSLIIPGL 102 Query: 118 QSVRTAGMGQGQASLVIGASVVAGALLVLLLQRA------GQGHDDAARQAALRRVWLFV 171 ++ +T G G A ++GAS++ G L +L ++R +G + LRR WLFV Sbjct: 103 EAAKTNGAGSWAAGGIVGASILLGGLALLAMERVLPHEHFIKGVEGGPSPRTLRRTWLFV 162 Query: 172 LTVGLHNLPEGLAVGVAYGGVPAEQASVLTFGIALQDIPEGMIVATALRGIGYSRADAIG 231 + LHNLPEGLA+GVAYGG QA LT GIA+QD+PEG++VA AL GY R A+ Sbjct: 163 FAIALHNLPEGLAIGVAYGGASPLQAGTLTAGIAIQDVPEGLVVAMALLAAGYRRWLAVL 222 Query: 232 CGILSGLVEPLAAVAGAAVVALSSALLPWALGGAAGAMLFVLAHEVIPDPHRRHDALAAT 291 G+ SGLVEPL AV GA+V+ LS+ LLPW LG AAGAMLFV++HE+IP+ HR+ AT Sbjct: 223 LGMASGLVEPLGAVLGASVIGLSAGLLPWGLGFAAGAMLFVISHEIIPESHRKGHESWAT 282 Query: 292 CCLIAGFVLMMVLDTAL 308 L+ GFVLMM+LDTAL Sbjct: 283 GGLMIGFVLMMLLDTAL 299 >E6V0M2.1 E6V0M2_VARPD Zinc/iron permease Length = 309 Score = 228 bits (580), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 137/272 (50%), Positives = 176/272 (64%), Gaps = 9/272 (3%) Query: 46 LACAAMGWWSVR-DPRIWHAYCGGMAAAAAPGAGTLPLFFSRRFSARMADCCTGFGAGVM 104 LA A+ W VR DP +W+A GG AA A GTLP+ FS++ R+ D GFGAGVM Sbjct: 37 LALASQFWQFVRSDPVVWNALLGGSVAALATALGTLPVVFSQKLPERLQDTLFGFGAGVM 96 Query: 105 LAASVFSLILPALQSVRTAGM---GQGQASLVIGASVVAGALLVLLLQRA-GQGHDDAAR 160 LAA FSLI+P L + + G+ G A VIGA+++ G ++++++ R H R Sbjct: 97 LAACAFSLIIPGLDAAKNIGVFGGGSWAAGGVIGAAILLGGIVLMVMDRVLPHEHFIKGR 156 Query: 161 Q----AALRRVWLFVLTVGLHNLPEGLAVGVAYGGVPAEQASVLTFGIALQDIPEGMIVA 216 + LRR WLFV + LHN+PEGLA+GV Y G +A L GIA+QD+PEG++VA Sbjct: 157 EGQSAKQLRRTWLFVFAIALHNVPEGLAIGVGYAGNNGLRADALATGIAIQDVPEGLVVA 216 Query: 217 TALRGIGYSRADAIGCGILSGLVEPLAAVAGAAVVALSSALLPWALGGAAGAMLFVLAHE 276 AL GY R A+ G+ SGLVEPL AV GAAVV S+ LLPW LG AAGAMLFV++HE Sbjct: 217 VALLAAGYKRWFAVVIGMASGLVEPLGAVLGAAVVGHSALLLPWGLGFAAGAMLFVISHE 276 Query: 277 VIPDPHRRHDALAATCCLIAGFVLMMVLDTAL 308 +IP+ HR+ AT L+ GFVLMM+LDTAL Sbjct: 277 IIPESHRKGHEAFATSGLMLGFVLMMLLDTAL 308 >Q7W0E6.1 Q7W0E6_BORPE Probable metal transporter Length = 297 Score = 224 bits (570), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 136/279 (48%), Positives = 182/279 (65%), Gaps = 11/279 (3%) Query: 40 VALALTLAC-AAMGWWSVRDPRIWH---AYCGGMAAAAAPGAGTLPLFFSRRFSARMADC 95 + LA+ +AC A W D R H A GGM AA A G +P+ FS+ S R+ DC Sbjct: 19 MTLAVLVACLACYQLWEFLDRRWPHVALAMAGGMVAAGATALGAVPVLFSQTLSQRVQDC 78 Query: 96 CTGFGAGVMLAASVFSLILPALQSVRTAGMGQGQASLVIGASVVAGALLVLLLQRA---- 151 GFGAGVMLAAS FSL++P + + G G A +++GA+++ G ++L R Sbjct: 79 MFGFGAGVMLAASAFSLVVPGIAAAGAQGYGPWGAGILVGAAILLGGAVLLASDRLLPHE 138 Query: 152 --GQGHDDAARQAALRRVWLFVLTVGLHNLPEGLAVGVAYGGVPAEQASVLTFGIALQDI 209 +G + A + LRR WLFV + LHN+PEGLA+GV Y G + + + L GIA+QD+ Sbjct: 139 HFIKGKEGRASRT-LRRTWLFVFAIMLHNVPEGLAIGVGYAGSDSLRGAALATGIAIQDV 197 Query: 210 PEGMIVATALRGIGYSRADAIGCGILSGLVEPLAAVAGAAVVALSSALLPWALGGAAGAM 269 PEG++VA AL GYSRA ++ G+LSGLVEPL A+ GAAVV S+A+LPW LG AAGAM Sbjct: 198 PEGLVVALALLAAGYSRAFSVALGMLSGLVEPLGAIVGAAVVGWSAAMLPWGLGFAAGAM 257 Query: 270 LFVLAHEVIPDPHRRHDALAATCCLIAGFVLMMVLDTAL 308 LFV++HE+IP+ HR+ + AT L+ GFVLMM+LDTAL Sbjct: 258 LFVISHEIIPESHRKGHEVPATAGLMLGFVLMMLLDTAL 296 >Q5P1X3.1 Q5P1X3_AROAE Probable metal transporter Length = 287 Score = 223 bits (569), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 137/257 (53%), Positives = 176/257 (68%), Gaps = 7/257 (2%) Query: 58 DPRIWHAYCGGMAAAAAPGAGTLPLFFSRRFSARMADCCTGFGAGVMLAASVFSLILPAL 117 DPRI A GG+ AA A GTLP+ S++FS R D GFGAGVMLAA FSL++PAL Sbjct: 31 DPRIAAALMGGLMAAGATALGTLPVMLSQQFSQRANDAMLGFGAGVMLAACTFSLVIPAL 90 Query: 118 QSVRTAGMGQGQASLVIGASVVAGALLVLLLQRAGQGHD------DAARQAALRRVWLFV 171 + R G G A L++G++V+ G L++L++ R H+ + R A+RRVWLFV Sbjct: 91 HAARALGAGAWDAGLMVGSAVLLGGLVLLVIDRL-TPHEHFLKGVEGPRVHAIRRVWLFV 149 Query: 172 LTVGLHNLPEGLAVGVAYGGVPAEQASVLTFGIALQDIPEGMIVATALRGIGYSRADAIG 231 L + LHNLPEGLA+GVA+ G A A L GI++QD+PEG++VA ALR +G +R + Sbjct: 150 LAISLHNLPEGLAIGVAFAGPDALAAQALATGISIQDVPEGLVVALALRRVGCTRTFSAM 209 Query: 232 CGILSGLVEPLAAVAGAAVVALSSALLPWALGGAAGAMLFVLAHEVIPDPHRRHDALAAT 291 GI SGLVEPL AV GAAVV +S+ LLPW L AAGAMLFV++HE+IP+ HR+ AT Sbjct: 210 LGIASGLVEPLFAVLGAAVVGVSADLLPWGLAAAAGAMLFVISHEIIPESHRQGHEAFAT 269 Query: 292 CCLIAGFVLMMVLDTAL 308 L+ GFVLMMVLDT+L Sbjct: 270 TGLMLGFVLMMVLDTSL 286 >B3PBP4.1 B3PBP4_CELJU GufA protein Length = 306 Score = 223 bits (567), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 129/255 (50%), Positives = 160/255 (62%), Gaps = 5/255 (1%) Query: 59 PRIWHAYCGGMAAAAAPGAGTLPLFFSRRFSARMADCCTGFGAGVMLAASVFSLILPALQ 118 P + A GG+ AA G + F R SAR+ D GFGAGVMLAASVFSLILP L Sbjct: 53 PNVPEALVGGLIAAGCTALGAASIVFFRNLSARILDSLLGFGAGVMLAASVFSLILPGLD 112 Query: 119 SVRTAGMGQGQASLVIGASVVAGALLVLLLQ-RAGQGHDDAARQ---AALRRVWLFVLTV 174 + R GMG QA+ +G SV+ G+ L+L + R H + + +RR WLFV + Sbjct: 113 AARGLGMGSWQAACTLGVSVLFGSCLMLFIDSRLPHEHFIKGVEGPVSIIRRTWLFVFAI 172 Query: 175 GLHNLPEGLAVGVAYGGVPAEQASVLTFGIALQDIPEGMIVATALRGIGYSRADAIGCGI 234 LHNLPEGLA+GVAY P E L GI++QDIPEG++VA AL GYSR A+ G Sbjct: 173 TLHNLPEGLAIGVAYASGP-EVGKPLMTGISIQDIPEGLVVAIALVAAGYSRTKAMLIGA 231 Query: 235 LSGLVEPLAAVAGAAVVALSSALLPWALGGAAGAMLFVLAHEVIPDPHRRHDALAATCCL 294 SGLVEPL A GA +V+ S LLPW LG AAGAMLFV++HE+IP+ HR+ + AT L Sbjct: 232 ASGLVEPLGAALGAGIVSHSVLLLPWGLGFAAGAMLFVVSHEIIPESHRKGHEIHATSGL 291 Query: 295 IAGFVLMMVLDTALS 309 GF+LMM+LD A Sbjct: 292 TIGFILMMILDNAFQ 306 >F0Q0P9.1 F0Q0P9_ACIAP Zinc/iron permease Length = 300 Score = 222 bits (565), Expect = 7e-56, Method: Compositional matrix adjust. Identities = 139/257 (54%), Positives = 175/257 (68%), Gaps = 6/257 (2%) Query: 58 DPRIWHAYCGGMAAAAAPGAGTLPLFFSRRFSARMADCCTGFGAGVMLAASVFSLILPAL 117 +PR+ A+ GG+ AA A GTLP+ FS+R S R+ D GFGAGVMLAAS FSLILP L Sbjct: 43 NPRVAQAWQGGLVAALATALGTLPVVFSQRLSERVQDTLFGFGAGVMLAASSFSLILPGL 102 Query: 118 QSVRTAGMGQGQASLVIGASVVAGALLVLLLQRA------GQGHDDAARQAALRRVWLFV 171 ++ + G G A +IGAS++ G L +L ++R +G + LRR WLFV Sbjct: 103 EAAKANGAGGWAAGGIIGASILLGGLALLAMERVLPHEHFIKGVEGGPSPRTLRRTWLFV 162 Query: 172 LTVGLHNLPEGLAVGVAYGGVPAEQASVLTFGIALQDIPEGMIVATALRGIGYSRADAIG 231 + LHNLPEGLA+GVAYGG QA LT GIA+QD+PEG++VA AL GY R A+ Sbjct: 163 FAIALHNLPEGLAIGVAYGGTSPLQAGTLTAGIAIQDVPEGLVVAVALLAAGYPRWLAVL 222 Query: 232 CGILSGLVEPLAAVAGAAVVALSSALLPWALGGAAGAMLFVLAHEVIPDPHRRHDALAAT 291 G+ SGLVEPL AV GA+V+ LS+ LLPW LG AAGAMLFV++HE+IP+ HR+ AT Sbjct: 223 LGMASGLVEPLGAVLGASVIGLSAGLLPWGLGFAAGAMLFVISHEIIPESHRKGHEAWAT 282 Query: 292 CCLIAGFVLMMVLDTAL 308 L+ GFVLMM+LDTAL Sbjct: 283 GGLMIGFVLMMLLDTAL 299 >Q7WP32.1 Q7WP32_BORBR Probable metal transporter Length = 297 Score = 221 bits (562), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 135/279 (48%), Positives = 180/279 (64%), Gaps = 11/279 (3%) Query: 40 VALALTLAC-AAMGWWSVRDPRIWH---AYCGGMAAAAAPGAGTLPLFFSRRFSARMADC 95 + LA+ +AC A W D R H A GGM AA A G +P+ FS+ S R+ DC Sbjct: 19 MTLAVLVACLACYQLWEFLDRRWPHVALAMAGGMVAAGATALGAVPVLFSQTLSQRVQDC 78 Query: 96 CTGFGAGVMLAASVFSLILPALQSVRTAGMGQGQASLVIGASVVAGALLVLLLQRA---- 151 GFGAGVMLAAS FSL+ P + + G G A +++GA+++ G ++L R Sbjct: 79 MFGFGAGVMLAASAFSLVAPGIAAAGAQGYGPWGAGILVGAAILLGGAVLLASDRLLPHE 138 Query: 152 --GQGHDDAARQAALRRVWLFVLTVGLHNLPEGLAVGVAYGGVPAEQASVLTFGIALQDI 209 +G + A + LRR WLFV + LHN+PEGLA+GV Y G + + + L GIA+QD+ Sbjct: 139 HFIKGKEGRASRT-LRRTWLFVFAIMLHNVPEGLAIGVGYAGSDSLRGAALATGIAIQDV 197 Query: 210 PEGMIVATALRGIGYSRADAIGCGILSGLVEPLAAVAGAAVVALSSALLPWALGGAAGAM 269 PEG++VA AL GY RA ++ G+LSGLVEPL A+ GAAVV S+A+LPW LG AAGAM Sbjct: 198 PEGLVVALALLAAGYGRAFSVALGMLSGLVEPLGAIVGAAVVGWSAAMLPWGLGFAAGAM 257 Query: 270 LFVLAHEVIPDPHRRHDALAATCCLIAGFVLMMVLDTAL 308 LFV++HE+IP+ HR+ + AT L+ GFVLMM+LDTAL Sbjct: 258 LFVISHEIIPESHRKGHEVPATAGLMLGFVLMMLLDTAL 296 >Q5R117.1 Q5R117_IDILO ZIP family metal transporter Length = 297 Score = 216 bits (549), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 135/259 (52%), Positives = 170/259 (65%), Gaps = 10/259 (3%) Query: 57 RDPRIWHAYCGGMAAAAAPGAGTLPLFFSRRFSARMADCCTGFGAGVMLAASVFSLILPA 116 + +A+ GM AA A AGTLP FSR S R+ GFG GVMLAAS+FSLI+PA Sbjct: 40 NQDHVRYAFYAGMVAAGATAAGTLPALFSRGLSTRLHAAILGFGGGVMLAASIFSLIVPA 99 Query: 117 LQSVRTAGMGQGQASLVIGASVVAGALLVLLLQRAGQGHDD-----AARQA-ALRRVWLF 170 L A A L + A+++ G+ L++ L+R+ H+ RQA L+R WLF Sbjct: 100 LDLFEIAAQTAWHAPLKVSAAILLGSFLMMALERS-VPHEHFIKGTEGRQALILKRSWLF 158 Query: 171 VLTVGLHNLPEGLAVGVAYGGVPAEQASVLTFGIALQDIPEGMIVATALRGIGYSRADAI 230 V + LHN+PEGLA+GVAY G AS L GI++QDIPEG +VA AL GYSR AI Sbjct: 159 VFAIILHNIPEGLAIGVAYAGDDTVGASTLATGISVQDIPEGFVVAMALLAAGYSRKIAI 218 Query: 231 GCGILSGLVEPLAAVAGAAVVALS-SALLPWALGGAAGAMLFVLAHEVIPDPHRRHDALA 289 G G+LSGLVEPL AV GA +ALS SA+LPW L AAGAMLFV++HE+IP+ H++ ++ Sbjct: 219 GVGMLSGLVEPLMAVIGA--IALSNSAVLPWGLAMAAGAMLFVISHEMIPESHKQGHEMS 276 Query: 290 ATCCLIAGFVLMMVLDTAL 308 AT L+ GFVLM VLDTAL Sbjct: 277 ATNGLMLGFVLMFVLDTAL 295