BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0068.p (650 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IYA7.1 D8IYA7_HERSS GGDEF domain/EAL domain signal transductio... 1314 0.0 B9JM33.1 B9JM33_AGRRK Sensory box/GGDEF family protein 669 0.0 D7HZR1.1 D7HZR1_PSESS GGDEF domain/EAL domain protein 661 0.0 Q48IW2.1 Q48IW2_PSE14 GGDEF domain/EAL domain protein 660 0.0 E7P683.1 E7P683_PSESG GGDEF domain/EAL domain-containing protein 660 0.0 E7PNX5.1 E7PNX5_PSESG GGDEF domain/EAL domain-containing protein 659 0.0 Q4ZSX2.1 Q4ZSX2_PSEU2 GGDEF 655 0.0 Q88BN4.1 Q88BN4_PSESM GGDEF domain/EAL domain protein 647 0.0 F0L9Q0.1 F0L9Q0_9RHIZ Sensory box/GGDEF family protein 647 0.0 E2M7Y8.1 E2M7Y8_PSESM GGDEF domain/EAL domain protein 645 0.0 >D8IYA7.1 D8IYA7_HERSS GGDEF domain/EAL domain signal transduction protein Length = 650 Score = 1314 bits (3401), Expect = 0.0, Method: Compositional matrix adjust. Identities = 645/650 (99%), Positives = 646/650 (99%) Query: 1 MRLSSWMSSLRNYWRVDHERPQLVIAQYQAFSTKMPMMYLILIINSWALAYTYLDLAPLW 60 MRLSSWMSSLRNYWRVDHERPQLVIAQYQAFSTKMPMMYLILIINSWALAYTYLDLAPLW Sbjct: 1 MRLSSWMSSLRNYWRVDHERPQLVIAQYQAFSTKMPMMYLILIINSWALAYTYLDLAPLW 60 Query: 61 LGLYFPAVLSVLCSVRLLFWWRNRHLVPTPVAAAQALRRTNLLVAPIALSFSLWSIMLFP 120 LGLYFPAVLSVLCSVRLLFWWRNRHLVPTPVAAAQALRRTNLLVAPIALSFSLWSIMLFP Sbjct: 61 LGLYFPAVLSVLCSVRLLFWWRNRHLVPTPVAAAQALRRTNLLVAPIALSFSLWSIMLFP 120 Query: 121 YGNAYAQAHVAFYMGITVICCIFCLMYLRSAALTGALIVNGIFTVFFLSTHIPVFVAAAL 180 YGNAYAQAHVAFYMGITVICCIFCLMYLRSAALTGALIVNGIFTVFFLSTHIPVFVAAAL Sbjct: 121 YGNAYAQAHVAFYMGITVICCIFCLMYLRSAALTGALIVNGIFTVFFLSTHIPVFVAAAL 180 Query: 181 NVVLVTIGMLVIVNSHYEDFTRLVEAQLRTAVLSDENLQLANVDSLTQIPNRRKFFAQLN 240 NVVLVTIGMLVIVNSHYEDFTRLVEAQLRTAVLSDENLQLANVDSLTQIPNRRKFFAQLN Sbjct: 181 NVVLVTIGMLVIVNSHYEDFTRLVEAQLRTAVLSDENLQLANVDSLTQIPNRRKFFAQLN 240 Query: 241 EICARAHGAQQRFAVAILDLDGFKAVNDLYGHSHGDRLLEQVGQRLLAACRDPALHLARL 300 EICARAHGAQQRFAVAILDLDGFKAVNDLYGHSHGDRLLEQVGQRLL ACRDPALHLARL Sbjct: 241 EICARAHGAQQRFAVAILDLDGFKAVNDLYGHSHGDRLLEQVGQRLLTACRDPALHLARL 300 Query: 301 GGDEFALIIDRDLSDAALQEIGQQLCHTLRPAFVLDKAVVQIAASVGVATFPDMAADAAA 360 GGDEFALIIDRDLSDAALQEIGQQLCHTLR AFVLDKAVVQIAASVGVATFPDMAADAA Sbjct: 301 GGDEFALIIDRDLSDAALQEIGQQLCHTLRRAFVLDKAVVQIAASVGVATFPDMAADAAT 360 Query: 361 LYEHADYALYQGKRERRGTVTLFSEHDKAQIRRKSNIEQALRLADFERELSVFFQPIVRL 420 LYEHADYALYQGKRERRGTVTLFSEHDKAQIRRKSNIEQALRLADFERELSVFFQPIVRL Sbjct: 361 LYEHADYALYQGKRERRGTVTLFSEHDKAQIRRKSNIEQALRLADFERELSVFFQPIVRL 420 Query: 421 DDGQVIAFEALARWHSTVKGAVSPVEFIPAAERMGIINQLSVILLRKALAAAASWPAQIR 480 DDGQVIAFEALARWHSTVKGAVSPVEFIPAAERMGIINQLSVILLRKALAAAASWPAQIR Sbjct: 421 DDGQVIAFEALARWHSTVKGAVSPVEFIPAAERMGIINQLSVILLRKALAAAASWPAQIR 480 Query: 481 LSFNLSANDINSSEGMAAIIKLIRESGFCPSRLDLEITETALLQDLEKTRQLIHSLRQLG 540 LSFNLSANDINSSEGMA IIKLIRESGFCPSRLDLEITETALLQDLEKTRQLIHSLRQLG Sbjct: 481 LSFNLSANDINSSEGMAEIIKLIRESGFCPSRLDLEITETALLQDLEKTRQLIHSLRQLG 540 Query: 541 CGITLDDFGTGYASLSHLHALPLTRIKIDKSFVADIGQDAVSLKIVKSLLALTLDMDLAC 600 CGITLDDFGTGYASLSHLHALPLTRIKIDKSFVADIGQDAVSLKIVKSLLALTLDMDLAC Sbjct: 541 CGITLDDFGTGYASLSHLHALPLTRIKIDKSFVADIGQDAVSLKIVKSLLALTLDMDLAC 600 Query: 601 VVEGLETPQHLAVLRELGAVYGQGYLYARPMAADDVAPWLAQRAARVQAG 650 VVEGLETPQHLAVLRELGA+YGQGYLYARPMAADDVAPWLAQRAARVQAG Sbjct: 601 VVEGLETPQHLAVLRELGAMYGQGYLYARPMAADDVAPWLAQRAARVQAG 650 >B9JM33.1 B9JM33_AGRRK Sensory box/GGDEF family protein Length = 635 Score = 669 bits (1726), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/622 (54%), Positives = 439/622 (70%), Gaps = 1/622 (0%) Query: 19 ERPQLVIAQYQAFSTKMPMMYLILIINSWALAYTYLDLAPLWLGLYFPAVLSVLCSVRLL 78 + P+L+ AQYQAFS ++P+MY+IL+ N+W LA T++ +AP WL +Y PA+L++ C+VR++ Sbjct: 6 DNPELLKAQYQAFSYQLPLMYVILLTNTWVLAATHISVAPAWLVVYIPALLTLACAVRIV 65 Query: 79 FWWRNRHLVPTPVAAAQALRRTNLLVAPIALSFSLWSIMLFPYGNAYAQAHVAFYMGITV 138 W R+ + PTP AA AL RTN L +A+ F+ W+++LFPYG+AYA++HVAFY ITV Sbjct: 66 SWSRSMRITPTPELAAHALTRTNRLAGIMAICFTAWALLLFPYGDAYAKSHVAFYTAITV 125 Query: 139 ICCIFCLMYLRSAALTGALIVNGIFTVFFLSTHIPVFVAAALNVVLVTIGMLVIVNSHYE 198 I IFCLM+LR AA T A IVNG F +FF+ + VF+A A+N LV+ MLVI+ +Y Sbjct: 126 IGVIFCLMHLRPAAFTVAAIVNGAFFIFFILSGNVVFIAIAINTALVSGTMLVILLVYYR 185 Query: 199 DFTRLVEAQLRTAVLSDENLQLANVDSLTQIPNRRKFFAQLNEICARAHGAQQRFAVAIL 258 DFTR+VEA++RT LS+EN +LAN+DSLT +PNRR FF+ L A R A I+ Sbjct: 186 DFTRMVEAKVRTEALSNENSRLANLDSLTDLPNRRAFFSHLTRAVCEAQAEGLRLAAGII 245 Query: 259 DLDGFKAVNDLYGHSHGDRLLEQVGQRLLAACRDPALHLARLGGDEFALIIDRDLSDAAL 318 DLDGFK VNDLYGH GD+LL +VGQRL C ++LARLGGDEFALI+ D L Sbjct: 246 DLDGFKPVNDLYGHGAGDKLLYEVGQRLARLCSG-NVYLARLGGDEFALIVSGLSDDTEL 304 Query: 319 QEIGQQLCHTLRPAFVLDKAVVQIAASVGVATFPDMAADAAALYEHADYALYQGKRERRG 378 +G LC TLR F+L +A VQI+ S+G A +P+MAA+ L+E ADYALY GKR RG Sbjct: 305 MALGDNLCLTLRTPFLLTEAAVQISGSIGFAVYPEMAANVEDLFERADYALYHGKRTNRG 364 Query: 379 TVTLFSEHDKAQIRRKSNIEQALRLADFERELSVFFQPIVRLDDGQVIAFEALARWHSTV 438 LFS A+IRR + IEQAL++A+ ELSV FQPIV + + I FEALARW S + Sbjct: 365 NAVLFSSDHDAEIRRDARIEQALQMANLREELSVMFQPIVDVRSHETIGFEALARWTSPI 424 Query: 439 KGAVSPVEFIPAAERMGIINQLSVILLRKALAAAASWPAQIRLSFNLSANDINSSEGMAA 498 G VSP +FIP AER G IN+++ LL KALAAAA WP IRLSFNLSA D+ S EG+ Sbjct: 425 IGKVSPAQFIPVAERAGFINRVTRPLLEKALAAAADWPMGIRLSFNLSAQDLTSPEGLLH 484 Query: 499 IIKLIRESGFCPSRLDLEITETALLQDLEKTRQLIHSLRQLGCGITLDDFGTGYASLSHL 558 +I +I SGF P RLDLEITETA D + + I +L+ LGCGI+LDDFGTGY+SLS L Sbjct: 485 LIAIIHASGFDPRRLDLEITETAFTADFGQIQSAITTLKALGCGISLDDFGTGYSSLSRL 544 Query: 559 HALPLTRIKIDKSFVADIGQDAVSLKIVKSLLALTLDMDLACVVEGLETPQHLAVLRELG 618 H+LPLT+IKID+SFV D+ + S KIVKSLLAL DM L CV+EG+ET + + L+ELG Sbjct: 545 HSLPLTKIKIDRSFVTDLHEKPASYKIVKSLLALGRDMGLDCVIEGVETREEMDALKELG 604 Query: 619 AVYGQGYLYARPMAADDVAPWL 640 + QGY Y+ P+ D+ +L Sbjct: 605 GLIVQGYFYSPPIQETDIRDFL 626 >D7HZR1.1 D7HZR1_PSESS GGDEF domain/EAL domain protein Length = 656 Score = 661 bits (1705), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/640 (52%), Positives = 434/640 (67%), Gaps = 4/640 (0%) Query: 3 LSSWMSSLRNYWRVDHERPQLVIAQYQAFSTKMPMMYLILIINSWALAYTYLDLAPLWLG 62 L +S+LR V + P+L+ AQY A S ++P+MY +L++N+WALA+T+ AP+WL Sbjct: 2 LKKLVSALRTVMSVPADNPRLLQAQYVALSRQLPLMYFVLLVNTWALAFTHWATAPMWLT 61 Query: 63 LYFPAVLSVLCSVRLLFWWR--NRHLVPTPVAAAQALRRTNLLVAPIALSFSLWSIMLFP 120 L PA+L+++C++R W NR P P LR TN L IA F+ WS+ L+P Sbjct: 62 LLVPALLTIVCAIRARKWLLTVNRP-PPAPTTILATLRGTNGLAGVIAAGFAAWSLSLYP 120 Query: 121 YGNAYAQAHVAFYMGITVICCIFCLMYLRSAALTGALIVNGIFTVFFLSTHIPVFVAAAL 180 YG+AYAQAHVAF+MGITVI CIFC+M+LR AALT A++VN F +FF STH F+A A+ Sbjct: 121 YGDAYAQAHVAFFMGITVIVCIFCMMHLRPAALTTAVVVNTAFVIFFASTHNITFIATAV 180 Query: 181 NVVLVTIGMLVIVNSHYEDFTRLVEAQLRTAVLSDENLQLANVDSLTQIPNRRKFFAQLN 240 N+VLV+IGML+I+ Y DFT LV Q+RT LS+ENL LAN DSLT +PNRR+FF L+ Sbjct: 181 NIVLVSIGMLIILQYQYRDFTSLVNVQIRTEQLSNENLLLANQDSLTGLPNRRQFFQTLD 240 Query: 241 EICARAHGAQQRFAVAILDLDGFKAVNDLYGHSHGDRLLEQVGQRLLAACRDPALHLARL 300 A + AV +LDLDGFK VNDLYGH GDRLL V +RL +A D +H++RL Sbjct: 241 TALQEALAQRTGLAVGVLDLDGFKPVNDLYGHRTGDRLLMLVAERLTSAFSD-TVHVSRL 299 Query: 301 GGDEFALIIDRDLSDAALQEIGQQLCHTLRPAFVLDKAVVQIAASVGVATFPDMAADAAA 360 GGDEFAL+I D+S+ AL G+ LC + +F L +QI A++G ATFP A +A Sbjct: 300 GGDEFALVIKGDISNDALLAFGKHLCELMHESFELSDMSIQIGATLGFATFPATADNATQ 359 Query: 361 LYEHADYALYQGKRERRGTVTLFSEHDKAQIRRKSNIEQALRLADFERELSVFFQPIVRL 420 L+E ADYALYQGK GT LFS + Q+ EQALR A+ E E V FQPI+ Sbjct: 360 LFEFADYALYQGKDHNPGTTCLFSASHREQLHADGVTEQALRRANLETEFYVLFQPIIES 419 Query: 421 DDGQVIAFEALARWHSTVKGAVSPVEFIPAAERMGIINQLSVILLRKALAAAASWPAQIR 480 + +AFEALARW S G+VSP FIP AER+G+IN+L+ LL AL A SWPA IR Sbjct: 420 CTRETVAFEALARWKSPELGSVSPAHFIPIAERIGMINKLTAPLLTHALKRALSWPAPIR 479 Query: 481 LSFNLSANDINSSEGMAAIIKLIRESGFCPSRLDLEITETALLQDLEKTRQLIHSLRQLG 540 LSFNLSA+D + E ++ I+++I SGF SRLDLEITETA++QD+ + +Q I RQLG Sbjct: 480 LSFNLSAHDCATWESVSTIVEIIENSGFDASRLDLEITETAVMQDIAQVQQAIAQFRQLG 539 Query: 541 CGITLDDFGTGYASLSHLHALPLTRIKIDKSFVADIGQDAVSLKIVKSLLALTLDMDLAC 600 CGI+LDDFGTGY+SLS LHAL LT++KID+SFV + + S KIVKSL+AL+LDM L C Sbjct: 540 CGISLDDFGTGYSSLSQLHALALTKLKIDRSFVTGVHDNPASYKIVKSLVALSLDMSLGC 599 Query: 601 VVEGLETPQHLAVLRELGAVYGQGYLYARPMAADDVAPWL 640 V+EG+ET L L LG QGY Y+ P++ + W+ Sbjct: 600 VIEGVETQDELNALTSLGCTMVQGYFYSPPISFEQTLVWI 639 >Q48IW2.1 Q48IW2_PSE14 GGDEF domain/EAL domain protein Length = 656 Score = 660 bits (1704), Expect = 0.0, Method: Compositional matrix adjust. Identities = 334/640 (52%), Positives = 434/640 (67%), Gaps = 4/640 (0%) Query: 3 LSSWMSSLRNYWRVDHERPQLVIAQYQAFSTKMPMMYLILIINSWALAYTYLDLAPLWLG 62 L +S+LR V + P+L+ AQY A S ++P+MY +L++N+WALA+T+ AP+WL Sbjct: 2 LKKLVSALRTVMSVPADNPRLLQAQYVALSRQLPLMYFVLLVNTWALAFTHWATAPMWLT 61 Query: 63 LYFPAVLSVLCSVRLLFWWR--NRHLVPTPVAAAQALRRTNLLVAPIALSFSLWSIMLFP 120 L PA+L+++C++R W NR P P LR TN L IA F+ WS+ L+P Sbjct: 62 LLVPALLTIVCAIRARKWLLTVNRP-PPAPTTILATLRGTNGLAGVIAAGFAAWSLSLYP 120 Query: 121 YGNAYAQAHVAFYMGITVICCIFCLMYLRSAALTGALIVNGIFTVFFLSTHIPVFVAAAL 180 YG+AYAQAHVAF+MGITVI CIFC+M+LR AALT A++VN F +FF STH F+A A+ Sbjct: 121 YGDAYAQAHVAFFMGITVIVCIFCMMHLRPAALTTAVVVNTAFVIFFASTHNITFIATAV 180 Query: 181 NVVLVTIGMLVIVNSHYEDFTRLVEAQLRTAVLSDENLQLANVDSLTQIPNRRKFFAQLN 240 N+VLV+IGML+I+ Y DFT LV Q+RT LS+ENL LAN DSLT +PNRR+FF L+ Sbjct: 181 NIVLVSIGMLIILQYQYRDFTSLVNVQIRTEQLSNENLLLANQDSLTGLPNRRQFFQTLD 240 Query: 241 EICARAHGAQQRFAVAILDLDGFKAVNDLYGHSHGDRLLEQVGQRLLAACRDPALHLARL 300 A + AV +LDLDGFK VNDLYGH GDRLL V +RL +A D +H++RL Sbjct: 241 TAMQEALAQRTGLAVGVLDLDGFKPVNDLYGHRTGDRLLMLVAERLTSASSD-TVHVSRL 299 Query: 301 GGDEFALIIDRDLSDAALQEIGQQLCHTLRPAFVLDKAVVQIAASVGVATFPDMAADAAA 360 GGDEFA++I D+S+ AL G+ LC + +F L +QI A++G ATFP A +A Sbjct: 300 GGDEFAVVIKGDISNDALLAFGKHLCELMHESFELSDMPIQIGATLGFATFPATADNATQ 359 Query: 361 LYEHADYALYQGKRERRGTVTLFSEHDKAQIRRKSNIEQALRLADFERELSVFFQPIVRL 420 L+E ADYALYQGK GT LFS + Q+ EQALR A+ E E V FQPI+ Sbjct: 360 LFEFADYALYQGKDHNPGTTCLFSASHREQLHADGVTEQALRRANLETEFYVLFQPIIES 419 Query: 421 DDGQVIAFEALARWHSTVKGAVSPVEFIPAAERMGIINQLSVILLRKALAAAASWPAQIR 480 + +AFEALARW S G+VSP FIP AER+G+IN+L+ LL AL A SWPA IR Sbjct: 420 CTRETVAFEALARWKSPELGSVSPAHFIPIAERIGMINKLTAPLLTHALKRALSWPAPIR 479 Query: 481 LSFNLSANDINSSEGMAAIIKLIRESGFCPSRLDLEITETALLQDLEKTRQLIHSLRQLG 540 LSFNLSA+D + E ++ I+++I SGF SRLDLEITETA++QD+ + +Q I RQLG Sbjct: 480 LSFNLSAHDCATWESVSTIVEIIENSGFDASRLDLEITETAVMQDIAQVQQAIAQFRQLG 539 Query: 541 CGITLDDFGTGYASLSHLHALPLTRIKIDKSFVADIGQDAVSLKIVKSLLALTLDMDLAC 600 CGI+LDDFGTGY+SLS LHAL LT++KID+SFV + + S KIVKSL+AL+LDM L C Sbjct: 540 CGISLDDFGTGYSSLSQLHALALTKLKIDRSFVTGVHDNPASYKIVKSLVALSLDMSLGC 599 Query: 601 VVEGLETPQHLAVLRELGAVYGQGYLYARPMAADDVAPWL 640 V+EG+ET L L LG QGY Y+ P++ + W+ Sbjct: 600 VIEGVETQDELNALTSLGCTMVQGYFYSPPISFEQTLVWI 639 >E7P683.1 E7P683_PSESG GGDEF domain/EAL domain-containing protein Length = 656 Score = 660 bits (1704), Expect = 0.0, Method: Compositional matrix adjust. Identities = 334/640 (52%), Positives = 434/640 (67%), Gaps = 4/640 (0%) Query: 3 LSSWMSSLRNYWRVDHERPQLVIAQYQAFSTKMPMMYLILIINSWALAYTYLDLAPLWLG 62 L +S+LR V + P+L+ AQY A S ++P+MY +L++N+WALA+T+ AP+WL Sbjct: 2 LKKLVSALRTVMSVPADNPRLLQAQYVALSRQLPLMYFVLLVNTWALAFTHWATAPMWLT 61 Query: 63 LYFPAVLSVLCSVRLLFWWR--NRHLVPTPVAAAQALRRTNLLVAPIALSFSLWSIMLFP 120 L PA+L+++C++R W NR P P LR TN L IA F+ WS+ L+P Sbjct: 62 LLVPALLTIVCAIRARKWLLTVNRP-PPAPTTILATLRGTNGLAGVIAAGFAAWSLSLYP 120 Query: 121 YGNAYAQAHVAFYMGITVICCIFCLMYLRSAALTGALIVNGIFTVFFLSTHIPVFVAAAL 180 YG+AYAQAHVAF+MGITVI CIFC+M+LR AALT A++VN F +FF STH F+A A+ Sbjct: 121 YGDAYAQAHVAFFMGITVIVCIFCMMHLRPAALTTAVVVNTAFVIFFASTHNITFIATAV 180 Query: 181 NVVLVTIGMLVIVNSHYEDFTRLVEAQLRTAVLSDENLQLANVDSLTQIPNRRKFFAQLN 240 N+VLV+IGML+I+ Y DFT LV Q+RT LS+ENL LAN DSLT +PNRR+FF L+ Sbjct: 181 NIVLVSIGMLIILQYQYRDFTSLVNVQIRTEQLSNENLLLANQDSLTGLPNRRQFFQTLD 240 Query: 241 EICARAHGAQQRFAVAILDLDGFKAVNDLYGHSHGDRLLEQVGQRLLAACRDPALHLARL 300 A + AV +LDLDGFK VNDLYGH GDRLL V +RL +A D +H++RL Sbjct: 241 TAMQEALAQRTGLAVGVLDLDGFKPVNDLYGHRTGDRLLMLVAERLTSASSD-TVHVSRL 299 Query: 301 GGDEFALIIDRDLSDAALQEIGQQLCHTLRPAFVLDKAVVQIAASVGVATFPDMAADAAA 360 GGDEFA++I D+S+ AL G+ LC + +F L +QI A++G ATFP A +A Sbjct: 300 GGDEFAVVIKGDISNDALLAFGKHLCELMHESFELSDMPIQIGATLGFATFPATADNATQ 359 Query: 361 LYEHADYALYQGKRERRGTVTLFSEHDKAQIRRKSNIEQALRLADFERELSVFFQPIVRL 420 L+E ADYALYQGK GT LFS + Q+ EQALR A+ E E V FQPI+ Sbjct: 360 LFEFADYALYQGKDHNPGTTCLFSASHREQLHADGVTEQALRRANLETEFYVLFQPIIES 419 Query: 421 DDGQVIAFEALARWHSTVKGAVSPVEFIPAAERMGIINQLSVILLRKALAAAASWPAQIR 480 + +AFEALARW S G+VSP FIP AER+G+IN+L+ LL AL A SWPA IR Sbjct: 420 CTRETVAFEALARWKSPELGSVSPAHFIPIAERIGMINKLTAPLLTHALKRALSWPAPIR 479 Query: 481 LSFNLSANDINSSEGMAAIIKLIRESGFCPSRLDLEITETALLQDLEKTRQLIHSLRQLG 540 LSFNLSA+D + E ++ I+++I SGF SRLDLEITETA++QD+ + +Q I RQLG Sbjct: 480 LSFNLSAHDCATWESVSTIVEIIENSGFDASRLDLEITETAVMQDIAQVQQAIAQFRQLG 539 Query: 541 CGITLDDFGTGYASLSHLHALPLTRIKIDKSFVADIGQDAVSLKIVKSLLALTLDMDLAC 600 CGI+LDDFGTGY+SLS LHAL LT++KID+SFV + + S KIVKSL+AL+LDM L C Sbjct: 540 CGISLDDFGTGYSSLSQLHALALTKLKIDRSFVTGVHDNPASYKIVKSLVALSLDMSLGC 599 Query: 601 VVEGLETPQHLAVLRELGAVYGQGYLYARPMAADDVAPWL 640 V+EG+ET L L LG QGY Y+ P++ + W+ Sbjct: 600 VIEGVETQDELNALTSLGCTMVQGYFYSPPISFEQTLVWI 639 >E7PNX5.1 E7PNX5_PSESG GGDEF domain/EAL domain-containing protein Length = 656 Score = 659 bits (1700), Expect = 0.0, Method: Compositional matrix adjust. Identities = 333/640 (52%), Positives = 433/640 (67%), Gaps = 4/640 (0%) Query: 3 LSSWMSSLRNYWRVDHERPQLVIAQYQAFSTKMPMMYLILIINSWALAYTYLDLAPLWLG 62 L +S+LR V + P+L+ AQY A S ++P+MY +L++N+WALA+T+ AP+WL Sbjct: 2 LKKLVSALRTVMSVPADNPRLLQAQYVALSRQLPLMYFVLLVNTWALAFTHWATAPMWLT 61 Query: 63 LYFPAVLSVLCSVRLLFWWR--NRHLVPTPVAAAQALRRTNLLVAPIALSFSLWSIMLFP 120 L PA+L+++C++R W NR P P LR TN L IA F+ WS+ L+P Sbjct: 62 LLVPALLTIVCAIRARKWLLTVNRP-PPAPTTILATLRGTNGLAGVIAAGFAAWSLSLYP 120 Query: 121 YGNAYAQAHVAFYMGITVICCIFCLMYLRSAALTGALIVNGIFTVFFLSTHIPVFVAAAL 180 YG+AYAQAHVAF+MGITVI CIFC+M+LR AALT A++VN F +FF STH F+A + Sbjct: 121 YGDAYAQAHVAFFMGITVIVCIFCMMHLRPAALTTAVVVNTAFVIFFASTHNITFIATVV 180 Query: 181 NVVLVTIGMLVIVNSHYEDFTRLVEAQLRTAVLSDENLQLANVDSLTQIPNRRKFFAQLN 240 N+VLV+IGML+I+ Y DFT LV Q+RT LS+ENL LAN DSLT +PNRR+FF L+ Sbjct: 181 NIVLVSIGMLIILQYQYRDFTSLVNVQIRTEQLSNENLLLANQDSLTGLPNRRQFFQTLD 240 Query: 241 EICARAHGAQQRFAVAILDLDGFKAVNDLYGHSHGDRLLEQVGQRLLAACRDPALHLARL 300 A + AV +LDLDGFK VNDLYGH GDRLL V +RL +A D +H++RL Sbjct: 241 TAMQEALAQRTGLAVGVLDLDGFKPVNDLYGHRTGDRLLMLVAERLTSASSD-TVHVSRL 299 Query: 301 GGDEFALIIDRDLSDAALQEIGQQLCHTLRPAFVLDKAVVQIAASVGVATFPDMAADAAA 360 GGDEFA++I D+S+ AL G+ LC + +F L +QI A++G ATFP A +A Sbjct: 300 GGDEFAVVIKGDISNDALLAFGKHLCELMHESFELSDMPIQIGATLGFATFPATADNATQ 359 Query: 361 LYEHADYALYQGKRERRGTVTLFSEHDKAQIRRKSNIEQALRLADFERELSVFFQPIVRL 420 L+E ADYALYQGK GT LFS + Q+ EQALR A+ E E V FQPI+ Sbjct: 360 LFEFADYALYQGKDHNPGTTCLFSASHREQLHADGVTEQALRRANLETEFYVLFQPIIES 419 Query: 421 DDGQVIAFEALARWHSTVKGAVSPVEFIPAAERMGIINQLSVILLRKALAAAASWPAQIR 480 + +AFEALARW S G+VSP FIP AER+G+IN+L+ LL AL A SWPA IR Sbjct: 420 CTRETVAFEALARWKSPELGSVSPAHFIPIAERIGMINKLTAPLLTHALKRALSWPAPIR 479 Query: 481 LSFNLSANDINSSEGMAAIIKLIRESGFCPSRLDLEITETALLQDLEKTRQLIHSLRQLG 540 LSFNLSA+D + E ++ I+++I SGF SRLDLEITETA++QD+ + +Q I RQLG Sbjct: 480 LSFNLSAHDCATWESVSTIVEIIENSGFDASRLDLEITETAVMQDIAQVQQAIAQFRQLG 539 Query: 541 CGITLDDFGTGYASLSHLHALPLTRIKIDKSFVADIGQDAVSLKIVKSLLALTLDMDLAC 600 CGI+LDDFGTGY+SLS LHAL LT++KID+SFV + + S KIVKSL+AL+LDM L C Sbjct: 540 CGISLDDFGTGYSSLSQLHALALTKLKIDRSFVTGVHDNPASYKIVKSLVALSLDMSLGC 599 Query: 601 VVEGLETPQHLAVLRELGAVYGQGYLYARPMAADDVAPWL 640 V+EG+ET L L LG QGY Y+ P++ + W+ Sbjct: 600 VIEGVETQDELNALTSLGCTMVQGYFYSPPISFEQTLVWI 639 >Q4ZSX2.1 Q4ZSX2_PSEU2 GGDEF Length = 656 Score = 655 bits (1690), Expect = 0.0, Method: Compositional matrix adjust. Identities = 331/634 (52%), Positives = 435/634 (68%), Gaps = 4/634 (0%) Query: 9 SLRNYWRVDHERPQLVIAQYQAFSTKMPMMYLILIINSWALAYTYLDLAPLWLGLYFPAV 68 +LR V + P+L+ AQY A S ++P+MY +L++N+WALA+T+ AP+WL L PA+ Sbjct: 8 ALRALMSVPADNPRLLQAQYVALSRQLPLMYFVLLVNTWALAFTHWRTAPVWLTLLVPAL 67 Query: 69 LSVLCSVRLLFWWR--NRHLVPTPVAAAQALRRTNLLVAPIALSFSLWSIMLFPYGNAYA 126 L+V+C VR W R NR P P LR T+ L IA F+ WS+ L+PYG+AY+ Sbjct: 68 LTVICGVRASKWLRTVNRP-PPAPAIILATLRGTHGLAGVIAAGFAAWSLSLYPYGDAYS 126 Query: 127 QAHVAFYMGITVICCIFCLMYLRSAALTGALIVNGIFTVFFLSTHIPVFVAAALNVVLVT 186 QAHVAF+MGITVI CIFC+M+LR AALT AL+VN F +FF ST+ F+A A+N+VLV+ Sbjct: 127 QAHVAFFMGITVIVCIFCMMHLRPAALTTALVVNTAFVIFFASTYNITFIATAVNIVLVS 186 Query: 187 IGMLVIVNSHYEDFTRLVEAQLRTAVLSDENLQLANVDSLTQIPNRRKFFAQLNEICARA 246 IGML+I++ Y DFT LV Q++T LS+ENL LAN DSLT +PNRR+FF L+ A Sbjct: 187 IGMLIILHYQYRDFTSLVNVQVKTEQLSNENLLLANQDSLTGLPNRRQFFQTLDTAMTEA 246 Query: 247 HGAQQRFAVAILDLDGFKAVNDLYGHSHGDRLLEQVGQRLLAACRDPALHLARLGGDEFA 306 + AV +LDLDGFK VNDLYGH GDRLL V +RL +A D +H++RLGGDEFA Sbjct: 247 MAQRSGLAVGVLDLDGFKPVNDLYGHRIGDRLLMLVAERLTSASSD-KVHVSRLGGDEFA 305 Query: 307 LIIDRDLSDAALQEIGQQLCHTLRPAFVLDKAVVQIAASVGVATFPDMAADAAALYEHAD 366 L+I D+ ALQ G+ LC + +F L +QI A++G+AT+P A +A L+E AD Sbjct: 306 LVIKGDIDSEALQAFGKHLCDLMHESFELSDMPIQIGATLGLATYPATADNATQLFEFAD 365 Query: 367 YALYQGKRERRGTVTLFSEHDKAQIRRKSNIEQALRLADFERELSVFFQPIVRLDDGQVI 426 YALYQGK GT LFS + Q+ EQALR A+ E E V FQPI+ + + Sbjct: 366 YALYQGKNHNPGTTCLFSASHREQLHADGVTEQALRRANLETEFHVLFQPIIESCTRETV 425 Query: 427 AFEALARWHSTVKGAVSPVEFIPAAERMGIINQLSVILLRKALAAAASWPAQIRLSFNLS 486 AFEALARW+S GAVSP FIP AER+G+IN+L+V LL +AL+ A SWPA +RLSFNLS Sbjct: 426 AFEALARWNSPELGAVSPAHFIPIAERIGMINKLTVPLLTQALSMALSWPAPVRLSFNLS 485 Query: 487 ANDINSSEGMAAIIKLIRESGFCPSRLDLEITETALLQDLEKTRQLIHSLRQLGCGITLD 546 A+D + E + I+++I SGF SRLDLEITETA++QD+ + +Q I R+LGCGI+LD Sbjct: 486 AHDCATWESVNRIVEIIEHSGFDASRLDLEITETAVMQDIAQVQQAITQFRKLGCGISLD 545 Query: 547 DFGTGYASLSHLHALPLTRIKIDKSFVADIGQDAVSLKIVKSLLALTLDMDLACVVEGLE 606 DFGTG++SLS LHAL LT++KID+SFV + + S KIVKSL+AL+LDM L CV+EG+E Sbjct: 546 DFGTGFSSLSQLHALALTKLKIDRSFVTGVHNNPASYKIVKSLVALSLDMSLGCVIEGVE 605 Query: 607 TPQHLAVLRELGAVYGQGYLYARPMAADDVAPWL 640 T L L LG QGY Y+ P++ + W+ Sbjct: 606 TQDELNALTTLGCTMVQGYFYSPPISFAETLAWI 639 >Q88BN4.1 Q88BN4_PSESM GGDEF domain/EAL domain protein Length = 649 Score = 647 bits (1668), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/640 (51%), Positives = 430/640 (67%), Gaps = 4/640 (0%) Query: 3 LSSWMSSLRNYWRVDHERPQLVIAQYQAFSTKMPMMYLILIINSWALAYTYLDLAPLWLG 62 L M +LR V + P+L+ AQY A S ++P+MY +L++N+WALA+T+ AP+WL Sbjct: 2 LKKMMDALRTLMSVPSDNPRLLQAQYIALSRQLPLMYFVLLVNTWALAFTHWATAPMWLT 61 Query: 63 LYFPAVLSVLCSVRLLFWWRNRHLVPTPVAAA--QALRRTNLLVAPIALSFSLWSIMLFP 120 L P VL++ C +R W + P P ++ + LR TN LV I+ +F+ WS+ ++P Sbjct: 62 LLVPTVLTIGCCIRARKWLLTVN-KPPPASSTILETLRGTNRLVGIISTAFAAWSLSMYP 120 Query: 121 YGNAYAQAHVAFYMGITVICCIFCLMYLRSAALTGALIVNGIFTVFFLSTHIPVFVAAAL 180 YG+AY QA VAF+MGITVI CIFC+M+L+SAAL A+IVN F +FF STH F+A A Sbjct: 121 YGDAYTQAQVAFFMGITVIVCIFCMMHLQSAALITAVIVNTAFVIFFASTHNITFIATAA 180 Query: 181 NVVLVTIGMLVIVNSHYEDFTRLVEAQLRTAVLSDENLQLANVDSLTQIPNRRKFFAQLN 240 N+VLV+IGML+I+ Y DFT LV AQ +T LS+ NL LAN DSLT +PNRR FF L+ Sbjct: 181 NIVLVSIGMLIILRHQYRDFTSLVNAQFKTEQLSNANLMLANRDSLTGLPNRRHFFQTLD 240 Query: 241 EICARAHGAQQRFAVAILDLDGFKAVNDLYGHSHGDRLLEQVGQRLLAACRDPALHLARL 300 A + AV +LDLDGFK VNDLYGHS GDRLL V +RL A D +H++RL Sbjct: 241 TAMNEALLQRSGLAVGVLDLDGFKPVNDLYGHSVGDRLLMLVAERLTTAASD-TVHVSRL 299 Query: 301 GGDEFALIIDRDLSDAALQEIGQQLCHTLRPAFVLDKAVVQIAASVGVATFPDMAADAAA 360 GGDEFAL+I D S+ AL G+ LC + +F L + +QI A++G AT+P A +A Sbjct: 300 GGDEFALVIKGDTSNEALLMFGKHLCTLMHESFELSEIPIQIGATLGFATYPATADNATQ 359 Query: 361 LYEHADYALYQGKRERRGTVTLFSEHDKAQIRRKSNIEQALRLADFERELSVFFQPIVRL 420 L+E+ADYALYQGK G+ +FS + Q+ EQALR A+ + E V FQPI+ Sbjct: 360 LFEYADYALYQGKNHNPGSTCIFSASHREQLSADGVTEQALRRANLKTEFHVLFQPIIES 419 Query: 421 DDGQVIAFEALARWHSTVKGAVSPVEFIPAAERMGIINQLSVILLRKALAAAASWPAQIR 480 + +AFEALARW S V GAVSP FIP AER+G+IN+L+ LL +AL A SWP+ IR Sbjct: 420 CTRETVAFEALARWDSPVLGAVSPAHFIPIAERIGMINELTAPLLTQALQRALSWPSPIR 479 Query: 481 LSFNLSANDINSSEGMAAIIKLIRESGFCPSRLDLEITETALLQDLEKTRQLIHSLRQLG 540 LSFNLSA+D + E + I+ +I SGF SRLDLEITETA++QD+++ +Q I RQLG Sbjct: 480 LSFNLSAHDCATWESVKRIVDIIENSGFDASRLDLEITETAVMQDIDQVQQAILRFRQLG 539 Query: 541 CGITLDDFGTGYASLSHLHALPLTRIKIDKSFVADIGQDAVSLKIVKSLLALTLDMDLAC 600 CGI+LDDFGTGY SLS LHALPLT++KID+SFV + + S KIVKSL+AL+LDM L C Sbjct: 540 CGISLDDFGTGYTSLSQLHALPLTKLKIDRSFVRCVHDNPASYKIVKSLVALSLDMSLGC 599 Query: 601 VVEGLETPQHLAVLRELGAVYGQGYLYARPMAADDVAPWL 640 V+EG+ET L L LG QGY Y+ P+ + W+ Sbjct: 600 VIEGVETQDELNALTSLGCTMVQGYFYSPPITFAETLVWI 639 >F0L9Q0.1 F0L9Q0_9RHIZ Sensory box/GGDEF family protein Length = 650 Score = 647 bits (1668), Expect = 0.0, Method: Compositional matrix adjust. Identities = 334/646 (51%), Positives = 436/646 (67%), Gaps = 2/646 (0%) Query: 1 MRLSSWMSSLRNYWRVDHERPQLVIAQYQAFSTKMPMMYLILIINSWALAYTYLDLAPLW 60 M +++ L ++ V + P LV AQY+AF+ +MPMMY ILI ++WALA T+L LAP W Sbjct: 1 MNITNAKQKLLDFMSVRSDNPDLVKAQYRAFTRQMPMMYFILISSTWALATTHLQLAPFW 60 Query: 61 LGLYFPAVLSVLCSVRLLFWWRNRHLVPTPVAAAQALRRTNLLVAPIALSFSLWSIMLFP 120 L + PA ++ C+VR+ FWWR R + P P A AL+RTN L A IA+ F+LWS +L P Sbjct: 61 LTIGIPAFFTLGCTVRIAFWWRTRGIDPAPKVAHAALQRTNRLAAGIAVVFTLWSFLLVP 120 Query: 121 YGNAYAQAHVAFYMGITVICCIFCLMYLRSAALTGALIVNGIFTVFFLSTHIPVFVAAAL 180 YG+AY Q+HVAFYM ITVI CIFCLMY+RSAA IVNG F +FFL++ P F+A A+ Sbjct: 121 YGDAYTQSHVAFYMAITVISCIFCLMYVRSAAFMVTAIVNGAFVIFFLASQQPTFIAIAI 180 Query: 181 NVVLVTIGMLVIVNSHYEDFTRLVEAQLRTAVLSDENLQLANVDSLTQIPNRRKFFAQLN 240 NV+LV GM+ I+ ++Y +F R++ +Q RT L++ENL LAN+DSLT++PNRR FFA L Sbjct: 181 NVLLVCAGMMSILLTNYRNFERMIVSQQRTEALNNENLLLANIDSLTELPNRRAFFAHLE 240 Query: 241 EICARAHGAQQRFAVAILDLDGFKAVNDLYGHSHGDRLLEQVGQRLLAACRDPALHLARL 300 +A A R A+ ++DLDGFK VNDLYGHS GDRLL V +RL RL Sbjct: 241 AEIEKARVAGTRLALGVIDLDGFKPVNDLYGHSVGDRLLVSVSKRLTDTLTTS--RAFRL 298 Query: 301 GGDEFALIIDRDLSDAALQEIGQQLCHTLRPAFVLDKAVVQIAASVGVATFPDMAADAAA 360 GGDEFA++ DA L + LR A+ L + V +AAS+G+A FP +A Sbjct: 299 GGDEFAIVAPIIPDDAQLVANANVISERLREAYHLPEGTVHVAASMGIAVFPCLALTLEQ 358 Query: 361 LYEHADYALYQGKRERRGTVTLFSEHDKAQIRRKSNIEQALRLADFERELSVFFQPIVRL 420 L++ ADYALY K+ RRG LF + QI ++ IE L+ + E ELSV FQPIV + Sbjct: 359 LFDRADYALYHAKKTRRGDAVLFDAEHEKQINIEARIEHLLKQKEIENELSVVFQPIVDI 418 Query: 421 DDGQVIAFEALARWHSTVKGAVSPVEFIPAAERMGIINQLSVILLRKALAAAASWPAQIR 480 DG+ FEALARWHS V G V P +F AER GI++ L+ LLR ALA+A+ W +R Sbjct: 419 RDGRAAGFEALARWHSPVLGHVPPAQFFAIAERAGIVSSLTRPLLRTALASASVWEPSLR 478 Query: 481 LSFNLSANDINSSEGMAAIIKLIRESGFCPSRLDLEITETALLQDLEKTRQLIHSLRQLG 540 LSFNLSA+D+NS EG+ ++I +I SGF +R+DLEITETA D E+ RQ + LR+LG Sbjct: 479 LSFNLSAHDLNSCEGVLSLIGIIENSGFDATRIDLEITETAFAHDFEQVRQSVEMLRRLG 538 Query: 541 CGITLDDFGTGYASLSHLHALPLTRIKIDKSFVADIGQDAVSLKIVKSLLALTLDMDLAC 600 CGI+LDDFGTGY+SL+ LHALPLT+IKID+SFV D+ + S KIVKSLL L+ DM L C Sbjct: 539 CGISLDDFGTGYSSLTRLHALPLTKIKIDRSFVTDLHEKPASYKIVKSLLTLSRDMGLEC 598 Query: 601 VVEGLETPQHLAVLRELGAVYGQGYLYARPMAADDVAPWLAQRAAR 646 VVEG+ET + LA L LGA QGY+YA P+ DV +L+ +A + Sbjct: 599 VVEGVETLEELAALEGLGATLVQGYIYAAPLREQDVREFLSGQAKK 644 >E2M7Y8.1 E2M7Y8_PSESM GGDEF domain/EAL domain protein Length = 656 Score = 645 bits (1664), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/642 (52%), Positives = 439/642 (68%), Gaps = 8/642 (1%) Query: 3 LSSWMSSLRNYWRVDHERPQLVIAQYQAFSTKMPMMYLILIINSWALAYTYLDLAPLWLG 62 L +LR V + P+L+ AQY A S ++P+MY +L++N+WALA+T+ + AP+WL Sbjct: 2 LKKLAGALRTLMSVPADNPRLLEAQYVALSRQLPLMYFVLLVNTWALAFTHRETAPVWLT 61 Query: 63 LYFPAVLSVLCSVRLLFWWR--NRHLVPTPVAAA--QALRRTNLLVAPIALSFSLWSIML 118 L P +L+V+C +R W NR P P AA +LR TN L IA F+ WS+ L Sbjct: 62 LLVPVLLTVICGIRARKWLLTVNR---PPPAAATILASLRGTNSLAGVIAAGFAAWSLSL 118 Query: 119 FPYGNAYAQAHVAFYMGITVICCIFCLMYLRSAALTGALIVNGIFTVFFLSTHIPVFVAA 178 +PYG YAQAHVAF+MGITVI CIFC+M+LR AALT A++VN F +FF STH +F+A Sbjct: 119 YPYGGPYAQAHVAFFMGITVIVCIFCMMHLRPAALTTAVVVNTAFVIFFASTHNLIFIAT 178 Query: 179 ALNVVLVTIGMLVIVNSHYEDFTRLVEAQLRTAVLSDENLQLANVDSLTQIPNRRKFFAQ 238 A+N+VLV+IGML+I++ Y DFT LV+ Q+RT LS+ENL LAN DSLT +PNRR+FF Sbjct: 179 AVNIVLVSIGMLIILHHQYRDFTSLVDVQVRTEQLSNENLLLANKDSLTGLPNRRQFFQT 238 Query: 239 LNEICARAHGAQQRFAVAILDLDGFKAVNDLYGHSHGDRLLEQVGQRLLAACRDPALHLA 298 L+ + A + + AV +LDLDGFK VNDLYGH GDRLL V +RL + D +H++ Sbjct: 239 LDAAMSEALALRSKLAVGVLDLDGFKPVNDLYGHRTGDRLLMLVAERLNSVASD-TVHVS 297 Query: 299 RLGGDEFALIIDRDLSDAALQEIGQQLCHTLRPAFVLDKAVVQIAASVGVATFPDMAADA 358 RLGGDEFAL+I D+S+ AL +G+ LC + +F L +QI A++G+ATFP A +A Sbjct: 298 RLGGDEFALVIKGDISNEALLALGKHLCDLMHESFELSDMPIQIGATLGMATFPATADNA 357 Query: 359 AALYEHADYALYQGKRERRGTVTLFSEHDKAQIRRKSNIEQALRLADFERELSVFFQPIV 418 L+E ADYALYQGK GT LFS + Q+ EQALR A+ E E V FQPI+ Sbjct: 358 TQLFEFADYALYQGKNHNPGTTCLFSASHREQLHTDGVTEQALRRANLETEFHVMFQPII 417 Query: 419 RLDDGQVIAFEALARWHSTVKGAVSPVEFIPAAERMGIINQLSVILLRKALAAAASWPAQ 478 + +AFEALARW+S GAVSP FIP AER+G+IN+L+ LL AL A SWPA Sbjct: 418 ESCTCETVAFEALARWNSPELGAVSPAHFIPIAERIGMINKLTAPLLTHALQMALSWPAP 477 Query: 479 IRLSFNLSANDINSSEGMAAIIKLIRESGFCPSRLDLEITETALLQDLEKTRQLIHSLRQ 538 IRLSFNLSA+D + E ++ I+++I SGF SRLDLEITETA++QD+ + +Q I RQ Sbjct: 478 IRLSFNLSAHDCATWESVSTIVEIIENSGFDASRLDLEITETAVMQDIAQVQQAIAQFRQ 537 Query: 539 LGCGITLDDFGTGYASLSHLHALPLTRIKIDKSFVADIGQDAVSLKIVKSLLALTLDMDL 598 LGCGI+LDDFGTG++SLS LHAL LT++KID+SFV + + S KIVKSL+AL+LDM L Sbjct: 538 LGCGISLDDFGTGFSSLSQLHALALTKLKIDRSFVTGVHDNPASYKIVKSLVALSLDMSL 597 Query: 599 ACVVEGLETPQHLAVLRELGAVYGQGYLYARPMAADDVAPWL 640 CV+EG+ET L L LG QGY Y+ P++ + WL Sbjct: 598 GCVIEGVETQDELNALTSLGCTMVQGYFYSPPISFAETLAWL 639