BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0022.p (275 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IXF1.1 D8IXF1_HERSS Enzyme with a TIM-barrel fold protein 541 e-152 Q2L1P6.1 Q2L1P6_BORA1 Putative uncharacterized protein 391 e-107 D0KAU2.1 D0KAU2_PECWW Alanine racemase domain protein 389 e-106 E3HHC0.1 E3HHC0_ACHXA Alanine racemase, N-terminal domain protei... 389 e-106 Q6CZV4.1 Q6CZV4_ERWCT Putative alanine racemase 388 e-106 E8U0S8.1 E8U0S8_ALIDB Alanine racemase domain protein 388 e-106 D0IWB8.1 D0IWB8_COMT2 Hypothetical conserved protein 386 e-105 D8DCZ3.1 D8DCZ3_COMTE Putative uncharacterized protein 385 e-105 B7X059.1 B7X059_COMTE Alanine racemase domain protein 384 e-104 A6SZK0.1 A6SZK0_JANMA Uncharacterized conserved protein 382 e-104 >D8IXF1.1 D8IXF1_HERSS Enzyme with a TIM-barrel fold protein Length = 270 Score = 541 bits (1394), Expect = e-152, Method: Compositional matrix adjust. Identities = 266/269 (98%), Positives = 268/269 (99%) Query: 6 MSDPQFPEDESTAIRHDMHGRWPAAASLDEFRANLAAVHRRIAAACERAGRPASSVRLLP 65 MSDPQFPEDESTAIRHDMHGRWPAAASLDEFRANLAAVHRRIAAACERAGRPASSVRLLP Sbjct: 1 MSDPQFPEDESTAIRHDMHGRWPAAASLDEFRANLAAVHRRIAAACERAGRPASSVRLLP 60 Query: 66 VSKTKPESSIRLAYAAGCRLLGENKPQEACHKWEATQDLSGLQWSVIGHLQTNKAKLVAR 125 VSKTKPESSIRLAYAAGC LLGENKPQEACHKWEATQDLSGLQWSVIGHLQTNKAKLVAR Sbjct: 61 VSKTKPESSIRLAYAAGCCLLGENKPQEACHKWEATQDLSGLQWSVIGHLQTNKAKLVAR 120 Query: 126 FAAEFQALDSLRVAQALERRLQQEGRGLDVFVQVNTSGEASKYGLAPEEVAPFLRQLHAY 185 FAAEFQALDSLRVAQALERRLQQEGRGLDVFVQVNTSGEASKYGLAPEEVAPFLRQLHAY Sbjct: 121 FAAEFQALDSLRVAQALERRLQQEGRGLDVFVQVNTSGEASKYGLAPEEVAPFLRQLHAY 180 Query: 186 PALRLRGLMTLAVFSPEPARVRPCFSLLRNLRERLRQDVPAGAQLDELSMGMSGDYEIAI 245 PALRLRGLMTLAVFSP+PARVRPCFSLLRNLRERLRQDVPAGAQLDELSMGMSGDYEIAI Sbjct: 181 PALRLRGLMTLAVFSPDPARVRPCFSLLRNLRERLRQDVPAGAQLDELSMGMSGDYEIAI 240 Query: 246 EEGATVVRVGQALFGARALPDSHYWPSPE 274 EEGATVVRVGQALFGARALPDSHYWPSP+ Sbjct: 241 EEGATVVRVGQALFGARALPDSHYWPSPD 269 >Q2L1P6.1 Q2L1P6_BORA1 Putative uncharacterized protein Length = 275 Score = 391 bits (1005), Expect = e-107, Method: Compositional matrix adjust. Identities = 195/251 (77%), Positives = 209/251 (83%) Query: 21 HDMHGRWPAAASLDEFRANLAAVHRRIAAACERAGRPASSVRLLPVSKTKPESSIRLAYA 80 HD+H RWP AAS+D+FR NLAAV RI AAC R GR S VRLLPVSKTKPE+S+RLAYA Sbjct: 14 HDLHNRWPQAASVDDFRHNLAAVQARIDAACARVGRKPSEVRLLPVSKTKPEASLRLAYA 73 Query: 81 AGCRLLGENKPQEACHKWEATQDLSGLQWSVIGHLQTNKAKLVARFAAEFQALDSLRVAQ 140 AGCR+ GENK QEA KWE QDL L WSVIGHLQTNKAKLVARFAAEFQALDSLR+A+ Sbjct: 74 AGCRMFGENKVQEAYGKWEGMQDLPDLGWSVIGHLQTNKAKLVARFAAEFQALDSLRLAE 133 Query: 141 ALERRLQQEGRGLDVFVQVNTSGEASKYGLAPEEVAPFLRQLHAYPALRLRGLMTLAVFS 200 ALERRLQ EGR LDVFVQVNTSGE SKYGLAP EVA FLRQL A+ ALR+RGLMTLA+FS Sbjct: 134 ALERRLQAEGRALDVFVQVNTSGEPSKYGLAPAEVAGFLRQLSAFSALRVRGLMTLALFS 193 Query: 201 PEPARVRPCFSLLRNLRERLRQDVPAGAQLDELSMGMSGDYEIAIEEGATVVRVGQALFG 260 E RVR CF LR LRERLRQ P LDELSMGMSGD+EIAIEEGATVVRVGQA+FG Sbjct: 194 AEGERVRQCFMQLRALRERLRQQAPGAVSLDELSMGMSGDFEIAIEEGATVVRVGQAIFG 253 Query: 261 ARALPDSHYWP 271 ARA PD +YWP Sbjct: 254 ARATPDDYYWP 264 >D0KAU2.1 D0KAU2_PECWW Alanine racemase domain protein Length = 270 Score = 389 bits (1000), Expect = e-106, Method: Compositional matrix adjust. Identities = 189/261 (72%), Positives = 220/261 (84%) Query: 11 FPEDESTAIRHDMHGRWPAAASLDEFRANLAAVHRRIAAACERAGRPASSVRLLPVSKTK 70 P T RHD HGR+P AA++++F+ NLAAV RIAAAC R GR ++VRLLPVSKTK Sbjct: 1 MPISSDTPTRHDSHGRYPEAATVEDFQRNLAAVQMRIAAACHRVGRDPATVRLLPVSKTK 60 Query: 71 PESSIRLAYAAGCRLLGENKPQEACHKWEATQDLSGLQWSVIGHLQTNKAKLVARFAAEF 130 PE+ +R+AY AGCR++GENK QEA KWEA QDL+ LQWSVIGHLQTNKAKLVARFA+EF Sbjct: 61 PENRLRMAYMAGCRIVGENKVQEANRKWEAMQDLADLQWSVIGHLQTNKAKLVARFASEF 120 Query: 131 QALDSLRVAQALERRLQQEGRGLDVFVQVNTSGEASKYGLAPEEVAPFLRQLHAYPALRL 190 QALDSLR+ +AL+RRL EGR LDVFVQVNTSGEASKYGL+PE+V F++ L A+PALR+ Sbjct: 121 QALDSLRLVEALDRRLLVEGRSLDVFVQVNTSGEASKYGLSPEDVPAFIQALPAFPALRV 180 Query: 191 RGLMTLAVFSPEPARVRPCFSLLRNLRERLRQDVPAGAQLDELSMGMSGDYEIAIEEGAT 250 RGLMTLA+FS E RVR CF LRNLR+RL+Q+ PAG LDELSMGMSGD+EIAIEEGAT Sbjct: 181 RGLMTLALFSNEAERVRQCFIRLRNLRDRLQQNAPAGIGLDELSMGMSGDFEIAIEEGAT 240 Query: 251 VVRVGQALFGARALPDSHYWP 271 VVRVGQA+FGAR LPDS+YWP Sbjct: 241 VVRVGQAIFGARPLPDSYYWP 261 >E3HHC0.1 E3HHC0_ACHXA Alanine racemase, N-terminal domain protein 2 EC=5.1.1.- Length = 280 Score = 389 bits (1000), Expect = e-106, Method: Compositional matrix adjust. Identities = 194/267 (72%), Positives = 219/267 (82%) Query: 6 MSDPQFPEDESTAIRHDMHGRWPAAASLDEFRANLAAVHRRIAAACERAGRPASSVRLLP 65 MS+ +D T +HD HGRWP A S+++FR NLAAV+ RIA A RAGR ++VRLLP Sbjct: 1 MSEQGPGQDNGTQTQHDQHGRWPQAQSVEDFRRNLAAVNGRIADAALRAGRDPATVRLLP 60 Query: 66 VSKTKPESSIRLAYAAGCRLLGENKPQEACHKWEATQDLSGLQWSVIGHLQTNKAKLVAR 125 VSKT E+ IRLAY AGCR LGENK QE KWEA DL+ L+WSVIGHLQTNKAKLVAR Sbjct: 61 VSKTVEEARIRLAYEAGCRYLGENKLQEVSRKWEAMADLTDLRWSVIGHLQTNKAKLVAR 120 Query: 126 FAAEFQALDSLRVAQALERRLQQEGRGLDVFVQVNTSGEASKYGLAPEEVAPFLRQLHAY 185 +AAEFQALDSLRVA+AL+RRLQ EGR LDVFVQVNTSGEASKYGL PEE A FLR+L A+ Sbjct: 121 YAAEFQALDSLRVAEALDRRLQAEGRQLDVFVQVNTSGEASKYGLQPEETAAFLRELPAF 180 Query: 186 PALRLRGLMTLAVFSPEPARVRPCFSLLRNLRERLRQDVPAGAQLDELSMGMSGDYEIAI 245 LR+RGLMTLA+FS E ARVR CF LLR LR++LRQ+ PAG LDELSMGMSGDYEIAI Sbjct: 181 SGLRVRGLMTLALFSAEAARVRECFVLLRTLRDQLRQEAPAGIGLDELSMGMSGDYEIAI 240 Query: 246 EEGATVVRVGQALFGARALPDSHYWPS 272 EEGATVVRVGQA+FGAR PDS+YWP+ Sbjct: 241 EEGATVVRVGQAIFGARNTPDSYYWPT 267 >Q6CZV4.1 Q6CZV4_ERWCT Putative alanine racemase Length = 270 Score = 388 bits (997), Expect = e-106, Method: Compositional matrix adjust. Identities = 189/261 (72%), Positives = 219/261 (83%) Query: 11 FPEDESTAIRHDMHGRWPAAASLDEFRANLAAVHRRIAAACERAGRPASSVRLLPVSKTK 70 P T RHD HGR+P AA++++F+ NLAAV RIAAAC R GR ++VRLLPVSKTK Sbjct: 1 MPISSDTPTRHDSHGRYPDAATVEDFQFNLAAVQMRIAAACHRVGRDPATVRLLPVSKTK 60 Query: 71 PESSIRLAYAAGCRLLGENKPQEACHKWEATQDLSGLQWSVIGHLQTNKAKLVARFAAEF 130 PES +R+AY AGCR+LGENK QEA KWEA QDL+ LQWSVIGHLQTNKAKLVARFA+EF Sbjct: 61 PESRLRMAYTAGCRILGENKVQEAYGKWEAMQDLADLQWSVIGHLQTNKAKLVARFASEF 120 Query: 131 QALDSLRVAQALERRLQQEGRGLDVFVQVNTSGEASKYGLAPEEVAPFLRQLHAYPALRL 190 QALDSLR+A+AL+RRL EGR LDVFVQVNTSGEASKYGL+PE+V F++ L A+ ALR+ Sbjct: 121 QALDSLRLAEALDRRLHVEGRSLDVFVQVNTSGEASKYGLSPEDVPAFIQALPAFSALRV 180 Query: 191 RGLMTLAVFSPEPARVRPCFSLLRNLRERLRQDVPAGAQLDELSMGMSGDYEIAIEEGAT 250 RGLMTLA+FS E RVR CF LRNLR+RL+Q+ P +LDELSMGMSGD+EIAIEEGAT Sbjct: 181 RGLMTLALFSSEAERVRQCFIRLRNLRDRLQQNAPVDIRLDELSMGMSGDFEIAIEEGAT 240 Query: 251 VVRVGQALFGARALPDSHYWP 271 VVRVGQA+FGAR LPDS+YWP Sbjct: 241 VVRVGQAIFGARPLPDSYYWP 261 >E8U0S8.1 E8U0S8_ALIDB Alanine racemase domain protein Length = 264 Score = 388 bits (996), Expect = e-106, Method: Compositional matrix adjust. Identities = 203/256 (79%), Positives = 225/256 (87%) Query: 17 TAIRHDMHGRWPAAASLDEFRANLAAVHRRIAAACERAGRPASSVRLLPVSKTKPESSIR 76 TA RHD HGR+P AA+L +F+ +LA V RIAAAC+RAGR +SVRLLPVSKT+PE+ +R Sbjct: 2 TATRHDQHGRYPQAATLQDFQRHLATVQARIAAACQRAGRDPASVRLLPVSKTQPEARVR 61 Query: 77 LAYAAGCRLLGENKPQEACHKWEATQDLSGLQWSVIGHLQTNKAKLVARFAAEFQALDSL 136 LA+AAGCRLLGENKPQEA KW ATQDL GL+WSVIGHLQTNKAKLVARFA+EFQALDSL Sbjct: 62 LAHAAGCRLLGENKPQEAYGKWLATQDLPGLRWSVIGHLQTNKAKLVARFASEFQALDSL 121 Query: 137 RVAQALERRLQQEGRGLDVFVQVNTSGEASKYGLAPEEVAPFLRQLHAYPALRLRGLMTL 196 RVA+ALERRLQ EGR LDVFVQVNTSGEASKYGL P EVA FLR L A+PALR+RGLMTL Sbjct: 122 RVAEALERRLQAEGRALDVFVQVNTSGEASKYGLLPREVAAFLRALPAFPALRVRGLMTL 181 Query: 197 AVFSPEPARVRPCFSLLRNLRERLRQDVPAGAQLDELSMGMSGDYEIAIEEGATVVRVGQ 256 A+FS + ARVR CF LLR LR+RLRQ+ PAG L+ELSMGMSGD+EIAIEEGATVVRVGQ Sbjct: 182 ALFSSDAARVRRCFVLLRTLRDRLRQEAPAGITLEELSMGMSGDFEIAIEEGATVVRVGQ 241 Query: 257 ALFGARALPDSHYWPS 272 ALFGARALPD HYWPS Sbjct: 242 ALFGARALPDGHYWPS 257 >D0IWB8.1 D0IWB8_COMT2 Hypothetical conserved protein Length = 275 Score = 386 bits (992), Expect = e-105, Method: Compositional matrix adjust. Identities = 188/262 (71%), Positives = 219/262 (83%) Query: 11 FPEDESTAIRHDMHGRWPAAASLDEFRANLAAVHRRIAAACERAGRPASSVRLLPVSKTK 70 P T RHD HG +P A ++++FR NLA V RIAAAC+R GR +SVRLLPVSKTK Sbjct: 2 MPMTSETPTRHDQHGLYPEAGTVEDFRRNLATVQERIAAACQRVGRDPASVRLLPVSKTK 61 Query: 71 PESSIRLAYAAGCRLLGENKPQEACHKWEATQDLSGLQWSVIGHLQTNKAKLVARFAAEF 130 P++S+RLAYAAGCRLLGENK QEA KWE+ QDL+ L+WSVIGHLQTNKA+LVARFA+EF Sbjct: 62 PQASLRLAYAAGCRLLGENKVQEAFGKWESMQDLADLRWSVIGHLQTNKARLVARFASEF 121 Query: 131 QALDSLRVAQALERRLQQEGRGLDVFVQVNTSGEASKYGLAPEEVAPFLRQLHAYPALRL 190 QALDSLRVA+AL+R LQ +GR LDVFVQVNTSGEASKYGL+PE V F++QL + ALR+ Sbjct: 122 QALDSLRVAEALDRHLQAQGRSLDVFVQVNTSGEASKYGLSPEAVPDFIQQLPVFSALRV 181 Query: 191 RGLMTLAVFSPEPARVRPCFSLLRNLRERLRQDVPAGAQLDELSMGMSGDYEIAIEEGAT 250 RGLMTLA+FS E RVR CF LLR LR+RL+Q PAG +LD LSMGMSGD+EIAIEEGAT Sbjct: 182 RGLMTLALFSAETERVRRCFILLRELRDRLQQSAPAGIELDALSMGMSGDFEIAIEEGAT 241 Query: 251 VVRVGQALFGARALPDSHYWPS 272 VVRVGQA+FGAR LPDS+YWP+ Sbjct: 242 VVRVGQAIFGARPLPDSYYWPT 263 >D8DCZ3.1 D8DCZ3_COMTE Putative uncharacterized protein Length = 274 Score = 385 bits (989), Expect = e-105, Method: Compositional matrix adjust. Identities = 188/262 (71%), Positives = 220/262 (83%) Query: 11 FPEDESTAIRHDMHGRWPAAASLDEFRANLAAVHRRIAAACERAGRPASSVRLLPVSKTK 70 P T RHD HG +P A ++++FR NLA V RIAAAC+RAGR +SVRLLPVSKTK Sbjct: 1 MPMTSETPTRHDQHGLYPEAGTVEDFRRNLATVQERIAAACQRAGRDPASVRLLPVSKTK 60 Query: 71 PESSIRLAYAAGCRLLGENKPQEACHKWEATQDLSGLQWSVIGHLQTNKAKLVARFAAEF 130 P++S+RLAYAAGCRLLGENK QEA KWE+ QDL+ L+WSVIGHLQTNKA+LVARFA+EF Sbjct: 61 PQASLRLAYAAGCRLLGENKVQEAFGKWESMQDLADLRWSVIGHLQTNKARLVARFASEF 120 Query: 131 QALDSLRVAQALERRLQQEGRGLDVFVQVNTSGEASKYGLAPEEVAPFLRQLHAYPALRL 190 QALDSLRVA+AL+R LQ +GR LDVFVQVNTSGEASKYGL PE+V F++QL + ALR+ Sbjct: 121 QALDSLRVAEALDRHLQGQGRSLDVFVQVNTSGEASKYGLNPEDVPGFIQQLPVFSALRV 180 Query: 191 RGLMTLAVFSPEPARVRPCFSLLRNLRERLRQDVPAGAQLDELSMGMSGDYEIAIEEGAT 250 RGLMTLA+FS E RVR CF LLR LR++L+Q PAG +LD LSMGMSGD+EIAIEEGAT Sbjct: 181 RGLMTLALFSAEAERVRRCFILLRELRDQLQQSAPAGMELDALSMGMSGDFEIAIEEGAT 240 Query: 251 VVRVGQALFGARALPDSHYWPS 272 VVRVGQA+FGAR LPDS+YWP+ Sbjct: 241 VVRVGQAIFGARPLPDSYYWPT 262 >B7X059.1 B7X059_COMTE Alanine racemase domain protein Length = 268 Score = 384 bits (985), Expect = e-104, Method: Compositional matrix adjust. Identities = 189/255 (74%), Positives = 216/255 (84%) Query: 17 TAIRHDMHGRWPAAASLDEFRANLAAVHRRIAAACERAGRPASSVRLLPVSKTKPESSIR 76 T RHD HG + ++++FR+NLA V RIAAAC+R GR +SVRLLPVSKTKP++S+R Sbjct: 5 TLTRHDQHGLYLEPRTVEDFRSNLATVQARIAAACQRVGRDPASVRLLPVSKTKPQASLR 64 Query: 77 LAYAAGCRLLGENKPQEACHKWEATQDLSGLQWSVIGHLQTNKAKLVARFAAEFQALDSL 136 LAYAAGCR LGENK QEA KWE+ QDL+ L+WSVIGHLQTNKA+LVARFA+EFQALDSL Sbjct: 65 LAYAAGCRWLGENKVQEALGKWESLQDLTDLRWSVIGHLQTNKARLVARFASEFQALDSL 124 Query: 137 RVAQALERRLQQEGRGLDVFVQVNTSGEASKYGLAPEEVAPFLRQLHAYPALRLRGLMTL 196 RVA+AL+RRLQ EGR LDVFVQVNTSGEASKYGL+PE V F+RQL + ALR+RGLMTL Sbjct: 125 RVAEALDRRLQAEGRSLDVFVQVNTSGEASKYGLSPEAVPDFIRQLPVFSALRVRGLMTL 184 Query: 197 AVFSPEPARVRPCFSLLRNLRERLRQDVPAGAQLDELSMGMSGDYEIAIEEGATVVRVGQ 256 A+FS E RVR CF LLR LR++LRQ PAG LD LSMGMSGD+EIAIEEGATVVRVGQ Sbjct: 185 ALFSAEAERVRRCFILLRQLRDQLRQGAPAGMALDALSMGMSGDFEIAIEEGATVVRVGQ 244 Query: 257 ALFGARALPDSHYWP 271 A+FGARALPDSHYWP Sbjct: 245 AIFGARALPDSHYWP 259 >A6SZK0.1 A6SZK0_JANMA Uncharacterized conserved protein Length = 267 Score = 382 bits (981), Expect = e-104, Method: Compositional matrix adjust. Identities = 188/248 (75%), Positives = 211/248 (85%) Query: 24 HGRWPAAASLDEFRANLAAVHRRIAAACERAGRPASSVRLLPVSKTKPESSIRLAYAAGC 83 HGR+PAA ++++F NL AV RIAAAC GR + VRLLPVSKTKPE+S+RLAYAAGC Sbjct: 11 HGRYPAATTVEDFIRNLTAVQLRIAAACRCVGRDPAEVRLLPVSKTKPEASLRLAYAAGC 70 Query: 84 RLLGENKPQEACHKWEATQDLSGLQWSVIGHLQTNKAKLVARFAAEFQALDSLRVAQALE 143 R LGENK QEA HKWEA QDL+ L WSVIGHLQTNKAKLVARFA EFQALDSLR+A+AL+ Sbjct: 71 RTLGENKVQEAHHKWEAMQDLTDLHWSVIGHLQTNKAKLVARFATEFQALDSLRLAEALD 130 Query: 144 RRLQQEGRGLDVFVQVNTSGEASKYGLAPEEVAPFLRQLHAYPALRLRGLMTLAVFSPEP 203 RRLQ EGR LDVFVQVNTSGEASKYGLAP +VA F++ L +Y ALR+RGLMTLA+FS E Sbjct: 131 RRLQIEGRSLDVFVQVNTSGEASKYGLAPADVAAFVQALPSYSALRVRGLMTLALFSSEE 190 Query: 204 ARVRPCFSLLRNLRERLRQDVPAGAQLDELSMGMSGDYEIAIEEGATVVRVGQALFGARA 263 RVR CF LLR LRE+LRQ PAG LDELSMGMSGD+EIAIEEGATVVRVGQA+FGAR Sbjct: 191 ERVRQCFFLLRTLREQLRQSAPAGISLDELSMGMSGDFEIAIEEGATVVRVGQAIFGARP 250 Query: 264 LPDSHYWP 271 +PDS+YWP Sbjct: 251 MPDSYYWP 258