BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0009.0007.p (65 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8ISL2.1 D8ISL2_HERSS Multidrug efflux system transmembrane protein 126 1e-27 Q214A9.1 Q214A9_RHOPB Hydrophobe/amphiphile efflux-1 HAE1 91 5e-17 F0LGL1.1 F0LGL1_9RHIZ Hydrophobe/amphiphile efflux-1 HAE1 90 1e-16 D4GKU3.1 D4GKU3_PANAM AcrB 89 2e-16 F2ERW6.1 F2ERW6_PANAN Acriflavine resistance protein B AcrB 87 7e-16 Q1DG48.1 Q1DG48_MYXXD Efflux transporter, HAE1 family, inner mem... 87 8e-16 D2ZCX9.1 D2ZCX9_9ENTR Efflux transporter, HAE1 family, inner mem... 87 1e-15 A6TA71.1 A6TA71_KLEP7 Acridine efflux pump 86 3e-15 A1TJ57.1 A1TJ57_ACIAC Transporter, hydrophobe/amphiphile efflux-... 84 8e-15 E6VHI0.1 E6VHI0_RHOPX Transporter, hydrophobe/amphiphile efflux-... 83 1e-14 >D8ISL2.1 D8ISL2_HERSS Multidrug efflux system transmembrane protein Length = 1033 Score = 126 bits (317), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 65/65 (100%), Positives = 65/65 (100%) Query: 1 MTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLAVLFVPVFFVLVLGCAQRL 60 MTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLAVLFVPVFFVLVLGCAQRL Sbjct: 969 MTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLAVLFVPVFFVLVLGCAQRL 1028 Query: 61 ARKGR 65 ARKGR Sbjct: 1029 ARKGR 1033 >Q214A9.1 Q214A9_RHOPB Hydrophobe/amphiphile efflux-1 HAE1 Length = 1036 Score = 90.9 bits (224), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 46/54 (85%), Positives = 51/54 (94%) Query: 1 MTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLAVLFVPVFFVLVL 54 MTS AFALGVVPLM+A GASAETQ AIGTGVFGGM+SATVLAVLFVPVF+V+V+ Sbjct: 968 MTSFAFALGVVPLMVARGASAETQHAIGTGVFGGMLSATVLAVLFVPVFYVVVM 1021 >F0LGL1.1 F0LGL1_9RHIZ Hydrophobe/amphiphile efflux-1 HAE1 Length = 1026 Score = 89.7 bits (221), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 43/59 (72%), Positives = 52/59 (88%) Query: 1 MTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLAVLFVPVFFVLVLGCAQR 59 MTSLAF LG+VPL++A GAS+ETQ AIGTG+FGGM+SATVLAV+FVPVF+VLV +R Sbjct: 968 MTSLAFTLGIVPLVIAKGASSETQNAIGTGLFGGMISATVLAVMFVPVFYVLVASLKRR 1026 >D4GKU3.1 D4GKU3_PANAM AcrB Length = 1033 Score = 89.0 bits (219), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 43/65 (66%), Positives = 53/65 (81%) Query: 1 MTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLAVLFVPVFFVLVLGCAQRL 60 MTSLAF LGVVPLMLASGASA TQ+AIG+GVFGGM+S T+LA+ FVP+F+ V+ ++L Sbjct: 969 MTSLAFTLGVVPLMLASGASARTQQAIGSGVFGGMISGTLLAIFFVPLFYFSVMKAVEKL 1028 Query: 61 ARKGR 65 K R Sbjct: 1029 KPKQR 1033 >F2ERW6.1 F2ERW6_PANAN Acriflavine resistance protein B AcrB Length = 1033 Score = 87.0 bits (214), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 42/65 (64%), Positives = 53/65 (81%) Query: 1 MTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLAVLFVPVFFVLVLGCAQRL 60 MTSLAF LGVVPL+LASGASA TQ+AIG+GVFGGM+S T+LA+ FVP+F+ V+ ++L Sbjct: 969 MTSLAFTLGVVPLILASGASARTQQAIGSGVFGGMISGTLLAIFFVPLFYFSVMKAVEKL 1028 Query: 61 ARKGR 65 K R Sbjct: 1029 KPKQR 1033 >Q1DG48.1 Q1DG48_MYXXD Efflux transporter, HAE1 family, inner membrane component Length = 1046 Score = 87.0 bits (214), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 45/59 (76%), Positives = 50/59 (84%) Query: 1 MTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLAVLFVPVFFVLVLGCAQR 59 MTSLAFALGVVPL++ASGASAETQRAIGTGVFGGMVS TVLA+ VP F+V V +R Sbjct: 970 MTSLAFALGVVPLVVASGASAETQRAIGTGVFGGMVSGTVLAIFLVPAFYVAVRSLLKR 1028 >D2ZCX9.1 D2ZCX9_9ENTR Efflux transporter, HAE1 family, inner membrane component Length = 1031 Score = 86.7 bits (213), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 45/64 (70%), Positives = 52/64 (81%), Gaps = 1/64 (1%) Query: 1 MTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLAVLFVPVFFVLVLGCAQRL 60 MTSLAF LGVVPLMLASGAS TQ AIGTGVFGGM+S T+LA+ FVPVFF+++ + Sbjct: 969 MTSLAFTLGVVPLMLASGASNSTQHAIGTGVFGGMISGTLLAIFFVPVFFIVIARFIES- 1027 Query: 61 ARKG 64 ARKG Sbjct: 1028 ARKG 1031 >A6TA71.1 A6TA71_KLEP7 Acridine efflux pump Length = 1038 Score = 85.5 bits (210), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 42/53 (79%), Positives = 46/53 (86%) Query: 1 MTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLAVLFVPVFFVLV 53 MTSLAF LGVVPLMLASGAS TQ AIGTGVFGGM+S T+LA+ FVPVFFV + Sbjct: 969 MTSLAFTLGVVPLMLASGASDSTQHAIGTGVFGGMISGTLLAIFFVPVFFVTI 1021 >A1TJ57.1 A1TJ57_ACIAC Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Length = 1052 Score = 83.6 bits (205), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 42/53 (79%), Positives = 48/53 (90%) Query: 1 MTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLAVLFVPVFFVLV 53 MTSLAF LGVVPL +ASGAS+ +QRAIGTGV GGM++ TVLAV+FVPVFFVLV Sbjct: 972 MTSLAFTLGVVPLFIASGASSASQRAIGTGVIGGMITGTVLAVIFVPVFFVLV 1024 >E6VHI0.1 E6VHI0_RHOPX Transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Length = 1050 Score = 83.2 bits (204), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 44/59 (74%), Positives = 48/59 (81%) Query: 1 MTSLAFALGVVPLMLASGASAETQRAIGTGVFGGMVSATVLAVLFVPVFFVLVLGCAQR 59 MTSLAF LGV PL ASG SA +Q AIGTGVFGGM+SATVLAVLFVPVF+V VL +R Sbjct: 969 MTSLAFILGVTPLAFASGVSAGSQNAIGTGVFGGMLSATVLAVLFVPVFYVFVLQKVER 1027