BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0136.p (399 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B9K5C0.1 B9K5C0_AGRVS Permeases of the major facilitator superfa... 190 4e-46 Q39TE6.1 Q39TE6_GEOMG Major facilitator superfamily MFS_1 140 5e-31 B9K0R1.1 B9K0R1_AGRVS MFS permease 121 2e-25 C6B8V7.1 C6B8V7_RHILS Major facilitator superfamily MFS_1 115 1e-23 D6EAA1.1 D6EAA1_9ACTN Sugar phosphate permease 84 3e-14 Q13TT2.1 Q13TT2_BURXL Major facilitator superfamily (MFS) transp... 68 3e-09 D5W518.1 D5W518_BURSC Major facilitator superfamily MFS_1 67 4e-09 >B9K5C0.1 B9K5C0_AGRVS Permeases of the major facilitator superfamily Length = 415 Score = 190 bits (482), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 136/389 (34%), Positives = 217/389 (55%), Gaps = 19/389 (4%) Query: 2 SLPIYGASVVNTYMATALGWNSQTLGLLISVNMTIAAIFSPIAANAIARIGIRNSIVVGC 61 + PIYGASV+NT M T+LGW+ LGLL+SVNM + I +P+ +A+ R G R ++ G Sbjct: 30 AFPIYGASVINTSMVTSLGWDRSLLGLLVSVNMAVTGITAPLVGSAVNRFGSRLVLIAGS 89 Query: 62 LTMVVGGAWLATVAAQPWEAIVAFSVLMGLTSAFSGIVPCQAGVAAWFVRRRTFAISVLF 121 L +++G + +A +PW+ +VAF +LMGL + G V QA VAAWF ++R A +VL+ Sbjct: 90 LLLLLGASAMAFWVEKPWQVVVAFGILMGLAMSAGGFVANQACVAAWFDKKRARAFAVLY 149 Query: 122 AVVGVASFAVIALIGAAVESPGGWRSGWWVFVGAGVVGLLTTLLFVRNAPTG-EDTKSSE 180 A +GV F LI ++ + WR+GW VF+GAG + L + VR+ P G D ++ Sbjct: 150 ATMGVGGFVAAPLISRSI-ALSDWRAGWLVFIGAGALALFLAIFVVRDTPPGASDANVAK 208 Query: 181 L-QWDEKQEQVGQATRELPLSKVVRSPLLLGVAFSMLAIASGSVFMIAHCQVYLRSLGIS 239 Q+D +Q G V +SP L V ++ +G F IAH L + Sbjct: 209 FAQFDASGDQKG---------SVYKSPALWLVITCIVTAGAGCSFYIAHGLALLHDSSFA 259 Query: 240 AAGAAFAMPLVSATMVVGNVGFNLLAASTDLRRAQIISMG--VFAVGLVALANLHSPNLI 297 AA ++ L++A+ ++GN F + A S L I++ G VF++G++ L H+ ++ Sbjct: 260 PTDAAASLSLMAASTLLGN--FAVGAFSERLGTRNILAAGLLVFSLGILTLGYAHNSIML 317 Query: 298 AAYIAVGVVGAGFGAAQVGVMGMLGHYWSTALFPMLTAIVLLVQTVGGCVVAILAGAYFD 357 AY ++GAG+GA QV M +L + + F ++ + + T+ V I+ G FD Sbjct: 318 YAYAV--LLGAGYGAVQVSSMALLSETFDSRHFAAVSGFAISMMTIASAVAPIVVGQLFD 375 Query: 358 AHHTYIPVLFAIVAVNLLAIIGVWATSRQ 386 HTY+P + I A+N +A + + AT+R+ Sbjct: 376 HTHTYMPSVLTIAALNGIAAV-LMATNRR 403 >Q39TE6.1 Q39TE6_GEOMG Major facilitator superfamily MFS_1 Length = 441 Score = 140 bits (352), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 114/394 (28%), Positives = 194/394 (49%), Gaps = 24/394 (6%) Query: 2 SLPIYGASVVNTYMATALGWNSQTLGLLISVNMTIAAIFSPIAANAIARIGIRNSIVVGC 61 + P GASV+N+YMA ++G +GL S+ + +A+ P+ A + + GIR ++ G Sbjct: 26 TFPYVGASVINSYMAESIGITKSIVGLGFSLFVLSSALSGPLVAYCVNKKGIRFTLASGG 85 Query: 62 LTMVVGGAWLATVAAQPWEAIVAFSVLMGLTSAFSGIVPCQAGVAAWFVRRRTFAISVLF 121 L + G +A ++ W+ ++ F V++G ++P Q GV WFVRRR A+S+ Sbjct: 86 LIVAFGALLMALTVSKGWQYVLTFGVVIGTGVGLGTVIPIQTGVTNWFVRRRALAMSIAL 145 Query: 122 AVVGVASFAVIALIGAAV-ESPGGWRSGWWVFVGAGVVGLLTTLLFVRNAPT-------- 172 + G SF L+ + S G W++GW V V G+ VRN P Sbjct: 146 SAAGFGSFIAAPLLNKIIAASNGNWKNGWLVVVATGLAAATIAAGGVRNTPASMGQFPDG 205 Query: 173 ---GEDTKSSELQWDEKQEQVGQATRELPLSKVVRSP---LLLGVAFSMLAIASGSVFMI 226 G+ ++++ + ++ Q++ P+ +V+++ L++ +FS LA+ + V Sbjct: 206 VPPGKSSENTARNAQVRSSRIYQSSEFWPVREVLKTKIFWLIIIASFSFLAVFNTCV--- 262 Query: 227 AHCQVYLRSLGISAAGAAFAMPLVSATMVVGNVGFNLLAASTDLRRAQIISMGVFA--VG 284 AH ++LRSLG S AA + L+ V G + +L + R I+S VF+ +G Sbjct: 263 AHGVIHLRSLGHSPQFAALSAGLLLLCSVGGKLFAGILGDRIEPRF--ILSAAVFSTLLG 320 Query: 285 LVALANLHSPNLIAAYIAVGVVGAGFGAAQVGVMGMLGHYWSTALFPMLTAIVLLVQTVG 344 VALAN + N Y+ VG GFGA+ V + +L +Y+ F L + L + G Sbjct: 321 AVALAN--ATNTAVVYLYACCVGVGFGASFVAMPTILANYYGVKSFAPLMGVALPLTNGG 378 Query: 345 GCVVAILAGAYFDAHHTYIPVLFAIVAVNLLAII 378 + +LAG +D +Y+ L+ + LL I Sbjct: 379 SAIAPLLAGIVYDRFGSYVLALYGGATIALLGAI 412 >B9K0R1.1 B9K0R1_AGRVS MFS permease Length = 440 Score = 121 bits (304), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 104/393 (26%), Positives = 189/393 (48%), Gaps = 8/393 (2%) Query: 2 SLPIYGASVVNTYMATALGWNSQTLGLLISVNMTIAAIFSPIAANAIARIGIRNSIVVGC 61 ++P G +VVN M T L + G+ + + + +P+ A I + G R+++ GC Sbjct: 40 AVPSIGTAVVNARMITDLNMDRAVFGMGFGLFVMMMGFQAPVVAVLIRKFGYRSTVAFGC 99 Query: 62 LTMVVGGAWLATVAAQPWEAIVAFSVLMGLTSAFSGIVPCQAGVAAWFVRRRTFAISVLF 121 L + +G +ATV W+ VAF +L G +G++P Q V WF RR A+S++F Sbjct: 100 LVLFLGSVAMATVVHNGWQYAVAFGLLAGSGVCIAGMLPAQTIVTRWFHARRALAVSIVF 159 Query: 122 AVVGVASFAVIALIGAAVESPGGWRSGWWVFVGAGVVGLLTTLLFVRNAPTGED-TKSSE 180 + V + F + + G WR+ WW+ G+ ++ ++T + + +++ Sbjct: 160 SAVEIGGFFSPPALERLMAISGDWRTAWWLIAGSAIIAMITAYIALDERRVENYISRNPA 219 Query: 181 LQWDEKQEQVGQATRELPLSKVVRSPLLLGVAFSMLAIASGSVFMIAHCQVYLRSLGISA 240 + + +V ++T L + + + + M +F++AH V+LR +G S Sbjct: 220 PSFARENSKVFKSTTHWTLREALGTKAYWLILIYMSIAGVAWIFLMAHGVVHLRDIGYSP 279 Query: 241 AGAAFAMPLVSATMVVGNV--GFNLLAASTDLRRAQIISMGVFAVGLVALANLHSPNLIA 298 A AA A+ ++ +GN+ GF S L A +++ +F +V + L+ Sbjct: 280 AEAANAVAVIIVASFIGNMTAGFLGDRISPSLISAASMALIIFGFCMVIKPVGFTGILLY 339 Query: 299 AYIAVGVVGAGFGAAQVGVMGMLGHYWSTALFPMLTAIVLLVQTVGGCVVAILAGAYFDA 358 A A G G+GA+QV +M +LG+Y+ A F + ++ V T+ + A AGA FD Sbjct: 340 ALPA----GIGYGASQVCLMALLGNYFGKASFSAILGSMMPVSTLCAAIGAGSAGAVFDQ 395 Query: 359 HHTYIPVLFAIVAVNLLAIIGVWATSRQPKHVG 391 TY V I+ + ++A + A S P++ G Sbjct: 396 TGTYEWVFITIITLCVVAFFAILAAS-PPQNRG 427 >C6B8V7.1 C6B8V7_RHILS Major facilitator superfamily MFS_1 Length = 441 Score = 115 bits (289), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 106/377 (28%), Positives = 168/377 (44%), Gaps = 21/377 (5%) Query: 4 PIYGASVVNTYMATALGWNSQTLGLLISVNMTIAAIFSPIAANAIARIGIRNSIVVGCLT 63 P G SV+N M L + GL + + + PI A + + G + ++ VGC Sbjct: 43 PSAGISVINAQMIADLDLDRSVFGLGFGMFVMMMGFQGPIVAMLMQKFGYQRTVTVGCFV 102 Query: 64 MVVGGAWLATVAAQPWEAIVAFSVLMGLTSAFSGIVPCQAGVAAWFVRRRTFAISVLFAV 123 +++G +AT+ W+ ++AF V++G G++P Q+ +A WF RR A+SV+ + Sbjct: 103 LLIGSVIMATLVNTGWQYVLAFGVIVGTGVCVGGMLPAQSAIARWFHVRRALAVSVVLSA 162 Query: 124 VGVASF-AVIALIGAAVESPGGWRSGWWVFVGAGVVGLLTTLL---------FVRNAPTG 173 V F + +L S WR GWWV G V LL T V PT Sbjct: 163 VEFGGFLSPPSLDRLLAASNNNWRLGWWVIAGLATVALLITRFALNERHVERLVAAHPTK 222 Query: 174 EDTKSSELQWDEKQEQVGQATRELPLSKVVRSPLLLGVAFSMLAIASGSVFMIAHCQVYL 233 +T + + QV RE + R+ L+ S+ +A VF++AH V+L Sbjct: 223 IETSGET---NVFKSQVHWLLRE---AVKTRAYWLILTYMSVAGVA--WVFLMAHGVVHL 274 Query: 234 RSLGISAAGAAFAMPLVSATMVVGNVGFNLLAASTDLRRAQIISMGVFAVGLVALANLHS 293 + +G S+A A AM + GN+ L + SM +G L +H Sbjct: 275 QDIGYSSADTAMAMAITIVASFFGNMAAGFLGDRISPAIIAVASMVFVTLGFFLL--VHP 332 Query: 294 PNLIAAYIAVGVVGAGFGAAQVGVMGMLGHYWSTALFPMLTAIVLLVQTVGGCVVAILAG 353 + G G+GA+QV VM +LG+Y+ FP + ++ V T+ A AG Sbjct: 333 QGFTGILMYAAPAGIGYGASQVCVMALLGNYFGRESFPSMFGSMMPVSTLCAASGAAAAG 392 Query: 354 AYFDAHHTYIPVLFAIV 370 A FD +Y ++F I+ Sbjct: 393 AIFDQTGSY-DLMFNII 408 >D6EAA1.1 D6EAA1_9ACTN Sugar phosphate permease Length = 451 Score = 84.3 bits (207), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 89/368 (24%), Positives = 166/368 (45%), Gaps = 21/368 (5%) Query: 8 ASVVNTYM--ATALGWNSQTLGLLISVNMTIAAIFSPIAANAIARIGIRNSIVVGCLTMV 65 A++VN M +LG N+ LG S+ + + + +P+ IA+ G R S+ +G M+ Sbjct: 51 ATIVNPLMLQDASLGMNATMLGTGFSLFVLVQGLSAPLVGALIAKKGARFSMALGAAVML 110 Query: 66 VGGAWLATVAAQPWEAIVAFSVLMGLTSAFSGIVPCQAGVAAWFVRRRTFAISVLFAVVG 125 + L + + P + F ++ + G + Q+ + WFV RR A++ + + Sbjct: 111 LAMLALIFLVSSPVAYFLVFGIVTSAATMMVGQLAVQSTIGDWFVARRGVAMTAMMVLGA 170 Query: 126 VASFAVIALIGAAVESPGG-WRSGWWVFVGAGVVGLLTTLLFVRNAPT--GED----TKS 178 ASF ++ A V + GG WRSGW++ VG + LL V+N P G+ Sbjct: 171 SASFVGPPVVNAIVGATGGTWRSGWYLLVGLSAALIPVALLLVKNKPADLGQHPDGVADP 230 Query: 179 SELQWDEKQEQVGQATRELPLSKVVRSPLLLGVAFSMLAIASGSVF-----MIAHCQVYL 233 S L K +V + T +P +V R+P AF ++++A+ F + ++ Sbjct: 231 SVLGGSGKGFKVYKNTDAVPFKRVARTP-----AFWLISLAATGGFASYTLATSQSALHF 285 Query: 234 RSLGISAAGAAFAMPLVSATMVVGNVGFNLLAASTDLRRAQIISMGVFAVGLVALANLHS 293 SLG + + ++ ++G + +++ + R + S + VG++A A + Sbjct: 286 SSLGFDSGLVVAGVAVMGGVSLLGKLLLGMVSDRIEPIRLIVASTVILVVGILAGAAAQN 345 Query: 294 PNLIAAYIAVGVVGAGFGAAQVGVMGMLGHYWSTALFPMLTAIVLLVQTVGGCVVAILAG 353 ++ A+ VG GFG + +Y+ + F +++ TV + I +G Sbjct: 346 EAMLFAFYV--CVGFGFGGVNAVFPTAMANYFGASSFSKNLGTGIMITTVVASALPIASG 403 Query: 354 AYFDAHHT 361 A FDA T Sbjct: 404 AVFDATGT 411 >Q13TT2.1 Q13TT2_BURXL Major facilitator superfamily (MFS) transporter, monocarboxylates Length = 427 Score = 67.8 bits (164), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 57/215 (26%), Positives = 95/215 (44%), Gaps = 16/215 (7%) Query: 9 SVVNTYMATALGWNSQTLGLLISVNMTIAAIFSPIAANAIARIGIRNSIVVGCLTMVVGG 68 SV+ + GW+ T+ L ISVN+ + + P AA A+ R G+R +++ TM G Sbjct: 37 SVMMVPLEHQFGWSRATISLAISVNIALYGLMGPFAAAAMQRFGVRPTLLAALGTMAAGV 96 Query: 69 AWLATVAAQPWEAIVAFSVLMGLTSAFSGIVPCQAGVAAWFVRRRTFAISVLFAVVGVAS 128 A L+++ PW+ ++ + V++G ++ + + V WF RR + +L A Sbjct: 97 A-LSSLMTHPWQMVLIWGVMVGGSTGVAALSLSATVVTRWFTTRRGLVMGILTASSATGQ 155 Query: 129 FAVIALIGAAVESPGGWRS-GWWVFVGAGVVGLLTTLLFVRNAPTGEDTKSSELQWDEKQ 187 + ++ AA+ GWR W V + A +V L L D K Sbjct: 156 LVFLPML-AAIAEHDGWRQVVWTVAIAAAIVIPLVAFLLPERP---SDMKLRPYGEPHDT 211 Query: 188 EQVGQATRELPLSKVVRSPLLLGVAFSMLAIASGS 222 G TR+ PL+ +AF LA+AS + Sbjct: 212 PINGTVTRQNPLA----------IAFGTLAMASKT 236 >D5W518.1 D5W518_BURSC Major facilitator superfamily MFS_1 Length = 427 Score = 67.4 bits (163), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 58/215 (26%), Positives = 97/215 (45%), Gaps = 16/215 (7%) Query: 9 SVVNTYMATALGWNSQTLGLLISVNMTIAAIFSPIAANAIARIGIRNSIVVGCLTMVVGG 68 SV+ + GW+ T+ L ISVN+ + + P AA A+ R G+R +++ TM G Sbjct: 37 SVMMVPLEHQFGWSRATISLAISVNIALYGLMGPFAAAAMQRFGVRPTLLTALGTMAAGV 96 Query: 69 AWLATVAAQPWEAIVAFSVLMGLTSAFSGIVPCQAGVAAWFVRRRTFAISVLFAVVGVAS 128 A L+++ PW+ ++ + V++G ++ + + V WF RR + +L A Sbjct: 97 A-LSSLMTHPWQMVLIWGVMVGGSTGVAALSLSATVVTRWFTTRRGLVMGILTASSATGQ 155 Query: 129 FAVIALIGAAVESPGGWRSGWWVF-VGAGVVGLLTTLLFVRNAPTGEDTKSSELQWDEKQ 187 + L+ AA+ GWR WV + AG+V L L E D + Sbjct: 156 LVFLPLL-AAIAEHYGWRQVVWVVALAAGIVIPLVAFLL------------PEHPADMQL 202 Query: 188 EQVGQATRELPLSKVVRSPLLLGVAFSMLAIASGS 222 G+ + P++ V L +AF LA AS + Sbjct: 203 RPYGEP-HDAPMNTTVTRQNPLAIAFGTLASASKT 236