BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0101.p (898 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IPE9.1 D8IPE9_HERSS Pyruvate dehydrogenase E1 component EC=1.2... 1864 0.0 F1W0U9.1 F1W0U9_9BURK Pyruvate dehydrogenase E1 component 1636 0.0 A6SVR6.1 A6SVR6_JANMA Pyruvate dehydrogenase E1 component EC=1.2... 1623 0.0 A4G353.1 A4G353_HERAR Pyruvate dehydrogenase E1 component EC=1.2... 1622 0.0 A6GQ96.1 A6GQ96_9BURK Pyruvate dehydrogenase E1 component EC=1.2... 1406 0.0 A2SHP5.1 A2SHP5_METPP Pyruvate dehydrogenase E1 component EC=1.2... 1402 0.0 B1XXD2.1 B1XXD2_LEPCP Pyruvate dehydrogenase E1 component EC=1.2... 1384 0.0 C3XBK8.1 C3XBK8_OXAFO Pyruvate dehydrogenase E1 component EC=1.2... 1378 0.0 C3X5D4.1 C3X5D4_OXAFO Pyruvate dehydrogenase E1 component EC=1.2... 1375 0.0 E6V0W8.1 E6V0W8_VARPD Pyruvate dehydrogenase E1 component EC=1.2... 1370 0.0 >D8IPE9.1 D8IPE9_HERSS Pyruvate dehydrogenase E1 component EC=1.2.4.1 Length = 898 Score = 1864 bits (4828), Expect = 0.0, Method: Compositional matrix adjust. Identities = 898/898 (100%), Positives = 898/898 (100%) Query: 1 MSAQIDQVLAQAANDPDVMETQEWLDALEAVIEKEGPDRAHYLMERMVDLARRRGAHIPF 60 MSAQIDQVLAQAANDPDVMETQEWLDALEAVIEKEGPDRAHYLMERMVDLARRRGAHIPF Sbjct: 1 MSAQIDQVLAQAANDPDVMETQEWLDALEAVIEKEGPDRAHYLMERMVDLARRRGAHIPF 60 Query: 61 SSNTAYVNTIPADQGEHCPGNLEYEERLRSWMRWNAMAMVVKANRVDGDLGGHLSSFASL 120 SSNTAYVNTIPADQGEHCPGNLEYEERLRSWMRWNAMAMVVKANRVDGDLGGHLSSFASL Sbjct: 61 SSNTAYVNTIPADQGEHCPGNLEYEERLRSWMRWNAMAMVVKANRVDGDLGGHLSSFASL 120 Query: 121 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREADGHG 180 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREADGHG Sbjct: 121 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREADGHG 180 Query: 181 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCGDGEM 240 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCGDGEM Sbjct: 181 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCGDGEM 240 Query: 241 DEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNVVKVI 300 DEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNVVKVI Sbjct: 241 DEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNVVKVI 300 Query: 301 WGSGWDELLAKDKDGILQKVMMETVDGEYQNYKAKDGAYVRKHFFGKHPKLLEMVSKMSD 360 WGSGWDELLAKDKDGILQKVMMETVDGEYQNYKAKDGAYVRKHFFGKHPKLLEMVSKMSD Sbjct: 301 WGSGWDELLAKDKDGILQKVMMETVDGEYQNYKAKDGAYVRKHFFGKHPKLLEMVSKMSD 360 Query: 361 DDIWRLTRGGHDPHKIYAAFKVAQESKDQPTVILAKSIKGYGFGKAGEARNTAHNTKKLD 420 DDIWRLTRGGHDPHKIYAAFKVAQESKDQPTVILAKSIKGYGFGKAGEARNTAHNTKKLD Sbjct: 361 DDIWRLTRGGHDPHKIYAAFKVAQESKDQPTVILAKSIKGYGFGKAGEARNTAHNTKKLD 420 Query: 421 DEAIRAMRDRFQLPISDADLPNIPFFKPSDDAPEMQYLHERRKALGGYLPQRRVQADEKL 480 DEAIRAMRDRFQLPISDADLPNIPFFKPSDDAPEMQYLHERRKALGGYLPQRRVQADEKL Sbjct: 421 DEAIRAMRDRFQLPISDADLPNIPFFKPSDDAPEMQYLHERRKALGGYLPQRRVQADEKL 480 Query: 481 PVPELSAFQAMLEPTAEGREISTTAAYSRVLTALLRDPNLGPRVVPIMVDESRTFGMEGL 540 PVPELSAFQAMLEPTAEGREISTTAAYSRVLTALLRDPNLGPRVVPIMVDESRTFGMEGL Sbjct: 481 PVPELSAFQAMLEPTAEGREISTTAAYSRVLTALLRDPNLGPRVVPIMVDESRTFGMEGL 540 Query: 541 FRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYSTNNRV 600 FRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYSTNNRV Sbjct: 541 FRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYSTNNRV 600 Query: 601 MIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHVFASA 660 MIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHVFASA Sbjct: 601 MIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHVFASA 660 Query: 661 IPNCIPYDPTFAHEVAVIIHDGLRRMVANQEDVFYYITVMNENYGHPGIKPGQEEGIIKG 720 IPNCIPYDPTFAHEVAVIIHDGLRRMVANQEDVFYYITVMNENYGHPGIKPGQEEGIIKG Sbjct: 661 IPNCIPYDPTFAHEVAVIIHDGLRRMVANQEDVFYYITVMNENYGHPGIKPGQEEGIIKG 720 Query: 721 LYLLNEGGKQNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSFTLLARDGQDV 780 LYLLNEGGKQNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSFTLLARDGQDV Sbjct: 721 LYLLNEGGKQNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSFTLLARDGQDV 780 Query: 781 ERWNMLHPAEAPKKSYFEQSLEGSEGPIVVSTDYMRTYAEQVRAFVPKGRSYKVLGTDGY 840 ERWNMLHPAEAPKKSYFEQSLEGSEGPIVVSTDYMRTYAEQVRAFVPKGRSYKVLGTDGY Sbjct: 781 ERWNMLHPAEAPKKSYFEQSLEGSEGPIVVSTDYMRTYAEQVRAFVPKGRSYKVLGTDGY 840 Query: 841 GRSDTRAKLREFFEVNRYFVTVAALKSLADEGKIKPEVVAQAIAKYGIDPNKPNPVTL 898 GRSDTRAKLREFFEVNRYFVTVAALKSLADEGKIKPEVVAQAIAKYGIDPNKPNPVTL Sbjct: 841 GRSDTRAKLREFFEVNRYFVTVAALKSLADEGKIKPEVVAQAIAKYGIDPNKPNPVTL 898 >F1W0U9.1 F1W0U9_9BURK Pyruvate dehydrogenase E1 component Length = 898 Score = 1636 bits (4237), Expect = 0.0, Method: Compositional matrix adjust. Identities = 765/897 (85%), Positives = 836/897 (93%) Query: 1 MSAQIDQVLAQAANDPDVMETQEWLDALEAVIEKEGPDRAHYLMERMVDLARRRGAHIPF 60 MSAQ+DQVLAQAA DPDV+ETQEWLDALEAVIE EGP+RAHYLMERMVDLARRRGAHIPF Sbjct: 1 MSAQLDQVLAQAATDPDVIETQEWLDALEAVIENEGPERAHYLMERMVDLARRRGAHIPF 60 Query: 61 SSNTAYVNTIPADQGEHCPGNLEYEERLRSWMRWNAMAMVVKANRVDGDLGGHLSSFASL 120 SSNTAYVNTIP D G HCPGNLE+EERLRSWMRWNAMAMVVK NR DGDLGGH+SSFASL Sbjct: 61 SSNTAYVNTIPNDLGAHCPGNLEFEERLRSWMRWNAMAMVVKTNRADGDLGGHISSFASL 120 Query: 121 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREADGHG 180 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTE+Q+++FRRE DG G Sbjct: 121 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEEQMLNFRREVDGKG 180 Query: 181 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCGDGEM 240 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHAR IAKTDNRKVW FCGDGEM Sbjct: 181 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHAREIAKTDNRKVWVFCGDGEM 240 Query: 241 DEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNVVKVI 300 DEPESMGAIGMAGRE L+NLV+VVNCNLQRLDGPVRGNGKIIQELE+DFRGAGWNVVKVI Sbjct: 241 DEPESMGAIGMAGREMLDNLVMVVNCNLQRLDGPVRGNGKIIQELEADFRGAGWNVVKVI 300 Query: 301 WGSGWDELLAKDKDGILQKVMMETVDGEYQNYKAKDGAYVRKHFFGKHPKLLEMVSKMSD 360 WG GWDELLAKDK+GILQ+VMMETVDGEYQNYKAKDGAYVRK+FFGKHPKLLEMV+ M+D Sbjct: 301 WGPGWDELLAKDKEGILQQVMMETVDGEYQNYKAKDGAYVRKNFFGKHPKLLEMVANMTD 360 Query: 361 DDIWRLTRGGHDPHKIYAAFKVAQESKDQPTVILAKSIKGYGFGKAGEARNTAHNTKKLD 420 DDIWRLTRGGHDPHKIYAAFK+AQE+K QPTV+L K++KG+G GK+GEARNTAH TKKLD Sbjct: 361 DDIWRLTRGGHDPHKIYAAFKIAQEAKGQPTVLLVKTVKGFGMGKSGEARNTAHQTKKLD 420 Query: 421 DEAIRAMRDRFQLPISDADLPNIPFFKPSDDAPEMQYLHERRKALGGYLPQRRVQADEKL 480 DE+IR MRDRF +PI D +L ++PFFKPSDDAPEM+YLHERR+ALGGYLPQRR+QADE L Sbjct: 421 DESIREMRDRFAIPIPDDELADVPFFKPSDDAPEMKYLHERRQALGGYLPQRRMQADETL 480 Query: 481 PVPELSAFQAMLEPTAEGREISTTAAYSRVLTALLRDPNLGPRVVPIMVDESRTFGMEGL 540 VPELSAF+A+L+PT+EGREISTT AY RV++ LLRD LGPRVVPI+VDE+RTFGMEGL Sbjct: 481 KVPELSAFKAVLDPTSEGREISTTQAYVRVISILLRDAALGPRVVPILVDEARTFGMEGL 540 Query: 541 FRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYSTNNRV 600 FRQIGIF+Q GQLYEPVDKDQV YYREDKAGQILQEGINEAG MSSWIAAATSYSTNNR+ Sbjct: 541 FRQIGIFNQQGQLYEPVDKDQVSYYREDKAGQILQEGINEAGAMSSWIAAATSYSTNNRI 600 Query: 601 MIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHVFASA 660 M+PFYT+YSMFGLQR+GDLAWAAGDMR+RGFL+GGTAGRTTLNGEGLQHEDGHSHV AS Sbjct: 601 MVPFYTFYSMFGLQRVGDLAWAAGDMRSRGFLMGGTAGRTTLNGEGLQHEDGHSHVLAST 660 Query: 661 IPNCIPYDPTFAHEVAVIIHDGLRRMVANQEDVFYYITVMNENYGHPGIKPGQEEGIIKG 720 IPNC+PYDPTFAHEVAVI+HDGL+RM+ QEDVFYYIT+MNENY HPGIK GQE GI+KG Sbjct: 661 IPNCLPYDPTFAHEVAVILHDGLKRMIEEQEDVFYYITLMNENYSHPGIKDGQEAGILKG 720 Query: 721 LYLLNEGGKQNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSFTLLARDGQDV 780 LYLL EG KLRVQL+GSGTILREVIAA DLL+DDW + ADVWSAPSFTLLARDGQDV Sbjct: 721 LYLLQEGQADTKLRVQLMGSGTILREVIAAVDLLQDDWGIGADVWSAPSFTLLARDGQDV 780 Query: 781 ERWNMLHPAEAPKKSYFEQSLEGSEGPIVVSTDYMRTYAEQVRAFVPKGRSYKVLGTDGY 840 ERWNMLHP E + ++ QSL+ ++GP+VV+TDYMRT+AEQVRAFVPKGRSYKVLGTDG+ Sbjct: 781 ERWNMLHPTEPERVAHITQSLQDTKGPVVVATDYMRTFAEQVRAFVPKGRSYKVLGTDGF 840 Query: 841 GRSDTRAKLREFFEVNRYFVTVAALKSLADEGKIKPEVVAQAIAKYGIDPNKPNPVT 897 GRSD+RAKLREFFEVNRY+VTVAALKSLADEG I+ +V QAI KYGI+P KPNPVT Sbjct: 841 GRSDSRAKLREFFEVNRYYVTVAALKSLADEGAIEQAIVEQAIVKYGINPEKPNPVT 897 >A6SVR6.1 A6SVR6_JANMA Pyruvate dehydrogenase E1 component EC=1.2.4.1 Length = 898 Score = 1623 bits (4204), Expect = 0.0, Method: Compositional matrix adjust. Identities = 756/898 (84%), Positives = 835/898 (92%) Query: 1 MSAQIDQVLAQAANDPDVMETQEWLDALEAVIEKEGPDRAHYLMERMVDLARRRGAHIPF 60 MSAQ+DQVLAQAANDPDVMETQEWLDALEAVIE EGPDRAHYLMER++DLARRRG+ +PF Sbjct: 1 MSAQLDQVLAQAANDPDVMETQEWLDALEAVIENEGPDRAHYLMERLIDLARRRGSQVPF 60 Query: 61 SSNTAYVNTIPADQGEHCPGNLEYEERLRSWMRWNAMAMVVKANRVDGDLGGHLSSFASL 120 SS TAYVNTIPA+ GE+ PGNLEYEERLRSWMRWNAMAMVVKANRVDGDLGGH+SSFASL Sbjct: 61 SSTTAYVNTIPAEMGENSPGNLEYEERLRSWMRWNAMAMVVKANRVDGDLGGHISSFASL 120 Query: 121 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREADGHG 180 ANMLG GFNHFWHAPTEDHGGDLLYIQGHSSPG+YARAFLEGRL+E+QLI+FRRE DG G Sbjct: 121 ANMLGTGFNHFWHAPTEDHGGDLLYIQGHSSPGVYARAFLEGRLSEEQLINFRREVDGKG 180 Query: 181 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCGDGEM 240 LSSYPHPKLMP+FWQFPTVSMGLGPLMAIYQARFLKYL AR IAKTDNRKVW FCGDGEM Sbjct: 181 LSSYPHPKLMPDFWQFPTVSMGLGPLMAIYQARFLKYLQARDIAKTDNRKVWVFCGDGEM 240 Query: 241 DEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNVVKVI 300 DE ESMGAIG+AGRE+L+NLV+VVNCNLQRLDGPVRGNGKIIQELE +FRGAGWNV+K+I Sbjct: 241 DEVESMGAIGVAGREQLDNLVMVVNCNLQRLDGPVRGNGKIIQELEGEFRGAGWNVIKII 300 Query: 301 WGSGWDELLAKDKDGILQKVMMETVDGEYQNYKAKDGAYVRKHFFGKHPKLLEMVSKMSD 360 WGS WD LLA+DK+GILQ+VMMET+DGEYQNYKAKDGAYVRKHFFGKHPKLLEMVS+MSD Sbjct: 301 WGSNWDPLLARDKEGILQRVMMETLDGEYQNYKAKDGAYVRKHFFGKHPKLLEMVSRMSD 360 Query: 361 DDIWRLTRGGHDPHKIYAAFKVAQESKDQPTVILAKSIKGYGFGKAGEARNTAHNTKKLD 420 DD+W L RGGHDPHK+YA FK AQE K QPTV+L K++KGYG GK+GEARNTAH TKKLD Sbjct: 361 DDLWHLLRGGHDPHKVYAGFKQAQEHKGQPTVLLVKTVKGYGMGKSGEARNTAHQTKKLD 420 Query: 421 DEAIRAMRDRFQLPISDADLPNIPFFKPSDDAPEMQYLHERRKALGGYLPQRRVQADEKL 480 DEA+R MRDRF LPI+D L +IPFFKP+DDAPEM+YLHERR ALGGYLPQRR QADEKL Sbjct: 421 DEAVREMRDRFNLPIADEHLADIPFFKPADDAPEMKYLHERRAALGGYLPQRRQQADEKL 480 Query: 481 PVPELSAFQAMLEPTAEGREISTTAAYSRVLTALLRDPNLGPRVVPIMVDESRTFGMEGL 540 PVPEL+AF+A+L+PTAEGREISTT AY R+++ LLRD NLG R+VPI+VDESRTFGMEGL Sbjct: 481 PVPELAAFKAVLDPTAEGREISTTQAYVRIISILLRDANLGQRLVPILVDESRTFGMEGL 540 Query: 541 FRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYSTNNRV 600 FRQIGI+++ GQLYEPVDKDQV +YREDKAGQILQEGINEAG M+SWIAAATSYSTNNR+ Sbjct: 541 FRQIGIYNREGQLYEPVDKDQVSFYREDKAGQILQEGINEAGAMASWIAAATSYSTNNRI 600 Query: 601 MIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHVFASA 660 M+PFYT+YSMFGLQRIGDLAWAAGDMRARGFL+GGTAGRTTLNGEGLQHEDGHSH+ AS Sbjct: 601 MVPFYTFYSMFGLQRIGDLAWAAGDMRARGFLLGGTAGRTTLNGEGLQHEDGHSHILAST 660 Query: 661 IPNCIPYDPTFAHEVAVIIHDGLRRMVANQEDVFYYITVMNENYGHPGIKPGQEEGIIKG 720 IPNCIPYDPTFAHEVAVI+HDGL+RM+ NQEDVFYYIT+MNENY PG+KPGQEEGI+KG Sbjct: 661 IPNCIPYDPTFAHEVAVIMHDGLKRMIENQEDVFYYITLMNENYAQPGLKPGQEEGILKG 720 Query: 721 LYLLNEGGKQNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSFTLLARDGQDV 780 LYLL EG K+ K RVQL+GSGTILREVIAAADLL+DDW V ADVWSAPSFTLLARDGQDV Sbjct: 721 LYLLQEGAKKAKNRVQLMGSGTILREVIAAADLLKDDWGVTADVWSAPSFTLLARDGQDV 780 Query: 781 ERWNMLHPAEAPKKSYFEQSLEGSEGPIVVSTDYMRTYAEQVRAFVPKGRSYKVLGTDGY 840 ERWNMLHP + P++++ SL+G+ GPIVV+TDYMRT+AEQVRAFVPK R+YKVLGTDG+ Sbjct: 781 ERWNMLHPTDKPRQAHITSSLQGTAGPIVVATDYMRTFAEQVRAFVPKDRTYKVLGTDGF 840 Query: 841 GRSDTRAKLREFFEVNRYFVTVAALKSLADEGKIKPEVVAQAIAKYGIDPNKPNPVTL 898 GRSD+RAKLREFFEVNRYFVTVAALK+LADEG I VVA+AIAKYGI+P K NPVTL Sbjct: 841 GRSDSRAKLREFFEVNRYFVTVAALKALADEGAIATSVVAEAIAKYGINPEKTNPVTL 898 >A4G353.1 A4G353_HERAR Pyruvate dehydrogenase E1 component EC=1.2.4.1 Length = 898 Score = 1622 bits (4199), Expect = 0.0, Method: Compositional matrix adjust. Identities = 758/898 (84%), Positives = 837/898 (93%) Query: 1 MSAQIDQVLAQAANDPDVMETQEWLDALEAVIEKEGPDRAHYLMERMVDLARRRGAHIPF 60 MSAQIDQVLAQAANDPDVMETQEWLDALEAVIE EGPDRAHYLMER++DLARRRGA IPF Sbjct: 1 MSAQIDQVLAQAANDPDVMETQEWLDALEAVIENEGPDRAHYLMERLIDLARRRGAQIPF 60 Query: 61 SSNTAYVNTIPADQGEHCPGNLEYEERLRSWMRWNAMAMVVKANRVDGDLGGHLSSFASL 120 SS TAYVNTIPAD GE+ PGNLEYEERLRSWMRWNAMAMVVKANRVDGDLGGH+SSFASL Sbjct: 61 SSTTAYVNTIPADLGENSPGNLEYEERLRSWMRWNAMAMVVKANRVDGDLGGHISSFASL 120 Query: 121 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREADGHG 180 ANMLG GFNHFWHAPTEDHGGDLLYIQGHSSPG+YARAFLEGRL+E+QLI+FRRE DGHG Sbjct: 121 ANMLGTGFNHFWHAPTEDHGGDLLYIQGHSSPGVYARAFLEGRLSEEQLINFRREVDGHG 180 Query: 181 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCGDGEM 240 LSSYPHPKLMP+FWQFPTVSMGLGPLMAIYQARFLKYL AR IAKTDNRKVW FCGDGEM Sbjct: 181 LSSYPHPKLMPDFWQFPTVSMGLGPLMAIYQARFLKYLQAREIAKTDNRKVWVFCGDGEM 240 Query: 241 DEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNVVKVI 300 DE ESMGAIG+AGRE+L+NLV+VVNCNLQRLDGPVRGNGKIIQELE +FRGAGWNV+K+I Sbjct: 241 DEVESMGAIGVAGREQLDNLVMVVNCNLQRLDGPVRGNGKIIQELEGEFRGAGWNVIKII 300 Query: 301 WGSGWDELLAKDKDGILQKVMMETVDGEYQNYKAKDGAYVRKHFFGKHPKLLEMVSKMSD 360 WGS WD LLAKDKDGILQ+VMMET+DGEYQNYKAKDGAYVRK+FFGKHPKLLEMVS+MSD Sbjct: 301 WGSNWDPLLAKDKDGILQRVMMETLDGEYQNYKAKDGAYVRKNFFGKHPKLLEMVSRMSD 360 Query: 361 DDIWRLTRGGHDPHKIYAAFKVAQESKDQPTVILAKSIKGYGFGKAGEARNTAHNTKKLD 420 DD+W L RGGHDPHK+YA FK AQE K QPTV+L K++KGYG GK+GEARNTAH TKKLD Sbjct: 361 DDLWHLLRGGHDPHKVYAGFKQAQEHKGQPTVLLVKTVKGYGMGKSGEARNTAHQTKKLD 420 Query: 421 DEAIRAMRDRFQLPISDADLPNIPFFKPSDDAPEMQYLHERRKALGGYLPQRRVQADEKL 480 DEA+R MRDRF LPI+D L +IPFFKP+DDAPEM+YLHERR ALGGYLPQRR QADEKL Sbjct: 421 DEAVREMRDRFNLPIADEHLADIPFFKPADDAPEMKYLHERRAALGGYLPQRRQQADEKL 480 Query: 481 PVPELSAFQAMLEPTAEGREISTTAAYSRVLTALLRDPNLGPRVVPIMVDESRTFGMEGL 540 PVPEL+AF+A+L+PTAEGREISTT AY R+++ LLRD +LG R+VPI+VDESRTFGMEGL Sbjct: 481 PVPELAAFKAVLDPTAEGREISTTQAYVRIISILLRDASLGKRLVPILVDESRTFGMEGL 540 Query: 541 FRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYSTNNRV 600 FRQIGI+++ GQLYEPVDKDQV YYREDKAGQILQEGINEAG M+SWIAAATSYSTNNR+ Sbjct: 541 FRQIGIYNREGQLYEPVDKDQVSYYREDKAGQILQEGINEAGAMASWIAAATSYSTNNRI 600 Query: 601 MIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHVFASA 660 M+PFYT+YSMFGLQRIGDLAWAAGDMRARGFL+GGTAGRTTLNGEGLQHEDGHSH+ AS Sbjct: 601 MVPFYTFYSMFGLQRIGDLAWAAGDMRARGFLLGGTAGRTTLNGEGLQHEDGHSHILAST 660 Query: 661 IPNCIPYDPTFAHEVAVIIHDGLRRMVANQEDVFYYITVMNENYGHPGIKPGQEEGIIKG 720 IPNC+PYDPTFAHEVAVI+ DGL+RM+ NQEDVFYYIT+MNENY PG+K GQE+ IIKG Sbjct: 661 IPNCVPYDPTFAHEVAVIMQDGLKRMIENQEDVFYYITLMNENYPQPGLKEGQEQDIIKG 720 Query: 721 LYLLNEGGKQNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSFTLLARDGQDV 780 LYLL EG K++K RVQL+GSGTILREVIAAADLL+DDW + +DVWSAPSFTLLARDGQDV Sbjct: 721 LYLLQEGAKKSKNRVQLMGSGTILREVIAAADLLKDDWGIVSDVWSAPSFTLLARDGQDV 780 Query: 781 ERWNMLHPAEAPKKSYFEQSLEGSEGPIVVSTDYMRTYAEQVRAFVPKGRSYKVLGTDGY 840 ERWNMLHPA+AP+ ++ QSL+G+ GPIVV+TDYMRT+AEQVRAF+PK R+YKVLGTDG+ Sbjct: 781 ERWNMLHPADAPRVAHVTQSLQGTSGPIVVATDYMRTFAEQVRAFIPKERTYKVLGTDGF 840 Query: 841 GRSDTRAKLREFFEVNRYFVTVAALKSLADEGKIKPEVVAQAIAKYGIDPNKPNPVTL 898 GRSD+RAKLREFFEVNRYFVTVAALK+LAD+G I P VVA+AIAKYGI+P K NPVTL Sbjct: 841 GRSDSRAKLREFFEVNRYFVTVAALKALADDGAIAPSVVAEAIAKYGINPEKVNPVTL 898 >A6GQ96.1 A6GQ96_9BURK Pyruvate dehydrogenase E1 component EC=1.2.4.1 Length = 901 Score = 1406 bits (3639), Expect = 0.0, Method: Compositional matrix adjust. Identities = 657/901 (72%), Positives = 767/901 (85%), Gaps = 9/901 (0%) Query: 1 MSAQIDQVLAQAANDPDVMETQEWLDALEAVIEKEGPDRAHYLMERMVDLARRRGAHIPF 60 MSAQ++ ++DPD ETQEWLDALEAV+E+EGP+RAHYL+E+++ AR GA IPF Sbjct: 1 MSAQLN---LPGSDDPDFQETQEWLDALEAVLEREGPERAHYLLEQLISKARLSGAFIPF 57 Query: 61 SSNTAYVNTIPADQGEHCPGNLEYEERLRSWMRWNAMAMVVKANRVD----GDLGGHLSS 116 S+NT YVNTIP CPGN+EYEERLRSWMRWNAMAMVV+AN+ GDLGGH++S Sbjct: 58 SANTEYVNTIPVHLETRCPGNMEYEERLRSWMRWNAMAMVVRANKKSPPDGGDLGGHIAS 117 Query: 117 FASLANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREA 176 FASLA MLG+GFNHFWHA E HGGDLLY+QGH SPGIYARAFLEGRLTE+QL +FR+E Sbjct: 118 FASLATMLGVGFNHFWHAEDESHGGDLLYLQGHVSPGIYARAFLEGRLTEEQLDNFRQEV 177 Query: 177 DGHGLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCG 236 DG GLSSYPHPKLMP+FWQFPTVSMGLGPLM IYQARFLKYLHARGI T RKVW FCG Sbjct: 178 DGKGLSSYPHPKLMPDFWQFPTVSMGLGPLMGIYQARFLKYLHARGICDTSKRKVWVFCG 237 Query: 237 DGEMDEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNV 296 DGEMDEPES+GAIGMA REKL+NLV VVNCNLQRLDGPVRGNGKIIQELE +FRG+GWNV Sbjct: 238 DGEMDEPESLGAIGMAAREKLDNLVFVVNCNLQRLDGPVRGNGKIIQELEGEFRGSGWNV 297 Query: 297 VKVIWGSGWDELLAKDKDGILQKVMMETVDGEYQNYKAKDGAYVRKHFFGKHPKLLEMVS 356 +KVIWG WDELLA+DKDG+++KVM+E VDGEYQN KA DGAYVRK+FFGKHPKLLEMV+ Sbjct: 298 LKVIWGGYWDELLARDKDGLMRKVMLEMVDGEYQNCKANDGAYVRKNFFGKHPKLLEMVA 357 Query: 357 KMSDDDIWRLTRGGHDPHKIYAAFKVAQESKDQPTVILAKSIKGYGFGKAGEARNTAHNT 416 +M+D+DIWRL RGGHDPHK++AA+ A + + QPTVILAK++KG+G GK G+ +NT H Sbjct: 358 RMTDEDIWRLNRGGHDPHKVHAAYDAAMKHEGQPTVILAKTVKGFGMGKVGQGKNTTHQQ 417 Query: 417 KKLDDEAIRAMRDRFQLPISDADLPNIPFFKPSDDAPEMQYLHERRKALGGYLPQRRVQA 476 KKLD ++I+ RDRF +P+SD + ++PF+KP+DDAPE++YLHERR+ALGGYLP+RR +A Sbjct: 418 KKLDIQSIKEFRDRFNIPVSDDIIEDVPFYKPADDAPEIKYLHERRQALGGYLPKRRREA 477 Query: 477 DEKLPVPELSAFQAMLEPTAEGREISTTAAYSRVLTALLRDPNLGPRVVPIMVDESRTFG 536 DEKL VP L AF+A+LEPT EGREISTT A+ RVLTAL+RD +G R+VPI+ DE+RTFG Sbjct: 478 DEKLKVPGLDAFEAVLEPTKEGREISTTQAFVRVLTALVRDKEIGQRIVPIVPDEARTFG 537 Query: 537 MEGLFRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYST 596 MEG+FRQ+GI+S GQLYEPVDKDQVMYYREDKAGQIL+EGINEAG SSWIAAATSYST Sbjct: 538 MEGMFRQLGIYSSQGQLYEPVDKDQVMYYREDKAGQILEEGINEAGAFSSWIAAATSYST 597 Query: 597 NNRVMIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHV 656 NNRVMIPFY YYSMFG QR+GDLAWAAGDM+ARGFL+GGTAGRTTLNGEGLQHEDGHSH+ Sbjct: 598 NNRVMIPFYIYYSMFGFQRVGDLAWAAGDMQARGFLLGGTAGRTTLNGEGLQHEDGHSHI 657 Query: 657 FASAIPNCIPYDPTFAHEVAVIIHDGLRRMVANQEDVFYYITVMNENYGHPGIKPGQEEG 716 +S IPNC+ YDPTFAHE+AVII GL+RMV +QE+VFYY+TVMNENY PG+K G EEG Sbjct: 658 LSSTIPNCVSYDPTFAHELAVIIQHGLKRMVEDQENVFYYLTVMNENYAQPGLKKGTEEG 717 Query: 717 IIKGLYLLNEGG--KQNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSFTLLA 774 I+KG+Y+ E K K RVQLLGSGTILRE + AA+LL DW V ADVWS SFT L Sbjct: 718 ILKGMYVCRESTLKKAGKKRVQLLGSGTILRESLEAAELLEKDWGVAADVWSVTSFTELR 777 Query: 775 RDGQDVERWNMLHPAEAPKKSYFEQSLEGSEGPIVVSTDYMRTYAEQVRAFVPKGRSYKV 834 R+G DVER NMLHP + K+SY E++L +EGPIV STDYM+ +A+Q+R F+PKGR YKV Sbjct: 778 REGLDVERENMLHPEQKSKQSYVEKALAKTEGPIVASTDYMKLFADQIRPFMPKGREYKV 837 Query: 835 LGTDGYGRSDTRAKLREFFEVNRYFVTVAALKSLADEGKIKPEVVAQAIAKYGIDPNKPN 894 LGTDG+GRSD R+KLRE FEVNR+FVTVAALK+LAD+G I V +AI KYGI+PNKPN Sbjct: 838 LGTDGFGRSDFRSKLREHFEVNRHFVTVAALKALADQGDIPLSTVGEAIKKYGINPNKPN 897 Query: 895 P 895 P Sbjct: 898 P 898 >A2SHP5.1 A2SHP5_METPP Pyruvate dehydrogenase E1 component EC=1.2.4.1 Length = 909 Score = 1402 bits (3629), Expect = 0.0, Method: Compositional matrix adjust. Identities = 662/907 (72%), Positives = 767/907 (84%), Gaps = 11/907 (1%) Query: 1 MSAQIDQVLAQAANDPDVMETQEWLDALEAVIEKEGPDRAHYLMERMVDLARRRGAHIPF 60 MSA + AAND D ET+EWL+AL AVI+ EGP RAH+L+ER++D AR+ G +PF Sbjct: 1 MSALPESFGRSAANDSDAQETREWLEALAAVIDSEGPQRAHFLLERLIDEARQAGIDMPF 60 Query: 61 SSNTAYVNTIPADQGEHCPGNLEYEERLRSWMRWNAMAMVVKANRVD----GDLGGHLSS 116 S+ T YVNTIPA Q H PG ++ EERLR++MRWNAMAMVVKANR+D GDLGGH+SS Sbjct: 61 SATTPYVNTIPAGQELHSPGQIDIEERLRAYMRWNAMAMVVKANRLDPADGGDLGGHISS 120 Query: 117 FASLANMLGIGFNHFWHAPTED----HGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHF 172 FASLA M G GFNHFWHA D HGGDLLYIQGHSSPGIYARAF+EGR+TE+QL++F Sbjct: 121 FASLATMFGAGFNHFWHADDTDQGGKHGGDLLYIQGHSSPGIYARAFMEGRITEEQLLNF 180 Query: 173 RREADGHGLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVW 232 R+E DG GLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIA T RKVW Sbjct: 181 RQEVDGKGLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIADTSKRKVW 240 Query: 233 AFCGDGEMDEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGA 292 FCGDGEMDEPES+GAIG+A REKL+NL+ V+NCNLQRLDGPVRGNGKIIQELE +FRG+ Sbjct: 241 VFCGDGEMDEPESLGAIGLAAREKLDNLIFVINCNLQRLDGPVRGNGKIIQELEGEFRGS 300 Query: 293 GWNVVKVIWGSGWDELLAKDKDGILQKVMMETVDGEYQNYKAKDGAYVRKHFFGKHPKLL 352 GWNV+K+IWGS WD LLA+DK+G+L+KVMMETVDG+YQ KA DGA+VRKHFFG+HPKLL Sbjct: 301 GWNVIKLIWGSYWDPLLARDKEGLLRKVMMETVDGDYQAMKANDGAFVRKHFFGQHPKLL 360 Query: 353 EMVSKMSDDDIWRLTRGGHDPHKIYAAFKVAQESKDQPTVILAKSIKGYGFGKAGEARNT 412 EMVSK+SDDDIWRL RGGHDPHK++AA+ A K QPTV+L K++KGYG GK GE +NT Sbjct: 361 EMVSKLSDDDIWRLNRGGHDPHKVHAAYHEAVNHKGQPTVLLIKTVKGYGMGKIGEGKNT 420 Query: 413 AHNTKKLDDEAIRAMRDRFQLPISDADLPNIPFFKPSDDAPEMQYLHERRKALGGYLPQR 472 AH TKKL DE ++A RDRF +PI D L +IPF+KP+DD PEMQYLHERRKALGGYLP+R Sbjct: 421 AHQTKKLVDEDVKAFRDRFNIPIPDDKLHDIPFYKPADDTPEMQYLHERRKALGGYLPKR 480 Query: 473 RVQADEKLPVPELSAFQAMLEPTAEGREISTTAAYSRVLTALLRDPNLGPRVVPIMVDES 532 R +ADE+LPVP+LS FQA++EPTAEGREISTT AY R L ALLRD LGPR VPI+VDE+ Sbjct: 481 RPKADEQLPVPDLSVFQAVMEPTAEGREISTTQAYVRCLNALLRDKALGPRTVPILVDEA 540 Query: 533 RTFGMEGLFRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAAT 592 RTFGMEGLFRQIGI++ GQ Y PVDKDQVMYY+EDKAGQILQEGINEAGGMSSWIAAAT Sbjct: 541 RTFGMEGLFRQIGIYNPAGQQYTPVDKDQVMYYKEDKAGQILQEGINEAGGMSSWIAAAT 600 Query: 593 SYSTNNRVMIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDG 652 SYSTNNR+MIPFY YYSMFGLQR+GDL WAAGDM+ARGFL+GGT+GRTTLNGEGLQHEDG Sbjct: 601 SYSTNNRIMIPFYIYYSMFGLQRVGDLCWAAGDMQARGFLLGGTSGRTTLNGEGLQHEDG 660 Query: 653 HSHVFASAIPNCIPYDPTFAHEVAVIIHDGLRRMVANQEDVFYYITVMNENYGHPGIKPG 712 HSH+ AS IPNCI YDPTFAHEVAVIIH GL+RMV Q++V++Y+T++NENY PG++PG Sbjct: 661 HSHILASTIPNCISYDPTFAHEVAVIIHHGLKRMVEQQDNVYFYLTLLNENYAQPGLRPG 720 Query: 713 QEEGIIKGLYLLNEGG--KQNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSF 770 E I+KG+YLL EGG K++ +V LLGSGTILRE IAA +LL DW V A+VWS PSF Sbjct: 721 TETQIVKGMYLLLEGGSKKKDAPQVNLLGSGTILRESIAAKELLEKDWGVSANVWSCPSF 780 Query: 771 TLLARDGQDVERWNMLHPAE-APKKSYFEQSLEGSEGPIVVSTDYMRTYAEQVRAFVPKG 829 LARDGQD +RWN+LHPA+ P+ + Q LE GP+V STDYM+ YAEQ+RAF+PKG Sbjct: 781 NELARDGQDADRWNLLHPADKKPRVPFVTQQLEPHAGPVVASTDYMKAYAEQIRAFIPKG 840 Query: 830 RSYKVLGTDGYGRSDTRAKLREFFEVNRYFVTVAALKSLADEGKIKPEVVAQAIAKYGID 889 RSYKVLGTDG+GRSD R KLRE FEVNR++V VAALK+LADEG + VA+AI KYGI+ Sbjct: 841 RSYKVLGTDGFGRSDFRTKLREHFEVNRHYVVVAALKALADEGTVPAAKVAEAIKKYGIN 900 Query: 890 PNKPNPV 896 +K NP+ Sbjct: 901 ADKINPL 907 >B1XXD2.1 B1XXD2_LEPCP Pyruvate dehydrogenase E1 component EC=1.2.4.1 Length = 903 Score = 1384 bits (3581), Expect = 0.0, Method: Compositional matrix adjust. Identities = 644/901 (71%), Positives = 754/901 (83%), Gaps = 5/901 (0%) Query: 1 MSAQIDQVLAQAANDPDVMETQEWLDALEAVIEKEGPDRAHYLMERMVDLARRRGAHIPF 60 MSA A A NDPD ET+EW+DAL AVI EG +RAH+L+E+++D AR+ G +PF Sbjct: 1 MSAVPQNQPAAATNDPDTQETREWMDALSAVIGAEGGERAHFLLEQLIDQARQAGIDVPF 60 Query: 61 SSNTAYVNTIPADQGEHCPGNLEYEERLRSWMRWNAMAMVVKANRVD----GDLGGHLSS 116 S+NTAYVNTIP DQ E CPGN+E EERLR++MRWNAMAMVVKANR + GDLGGH+ S Sbjct: 61 SANTAYVNTIPTDQEERCPGNIEIEERLRAYMRWNAMAMVVKANRHNPEDGGDLGGHIGS 120 Query: 117 FASLANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREA 176 FASLA+M G GFNHFWHA E+HGGD LYIQGH SPG+YARA++EGRLTE+QL++FR+E Sbjct: 121 FASLAHMFGAGFNHFWHAENENHGGDCLYIQGHVSPGVYARAYMEGRLTEEQLLNFRQEV 180 Query: 177 DGHGLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCG 236 DG GLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIA T+NRKVW FCG Sbjct: 181 DGKGLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIANTENRKVWVFCG 240 Query: 237 DGEMDEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNV 296 DGEMDEPES+GAIG+A RE L+NL+ V+NCNLQRLDGPVRGN KI+QELE +FRG+GWNV Sbjct: 241 DGEMDEPESLGAIGLAARENLDNLIFVINCNLQRLDGPVRGNSKIVQELEGEFRGSGWNV 300 Query: 297 VKVIWGSGWDELLAKDKDGILQKVMMETVDGEYQNYKAKDGAYVRKHFFGKHPKLLEMVS 356 +K++WGSGWD LLA+DKDG L+K+MMET+DG+YQ++KA DGAYVRKHFFG+ P+ LEMV+ Sbjct: 301 IKLLWGSGWDALLARDKDGALRKLMMETLDGDYQSFKANDGAYVRKHFFGRDPRTLEMVA 360 Query: 357 KMSDDDIWRLTRGGHDPHKIYAAFKVAQESKDQPTVILAKSIKGYGFGKAGEARNTAHNT 416 KMSDDDIW L RGGHDP K+YAA+ A K QPTV+L K++KG+G GK GE +NT H T Sbjct: 361 KMSDDDIWNLKRGGHDPQKVYAAYHKAVNHKGQPTVLLIKTVKGFGMGKVGEGKNTVHQT 420 Query: 417 KKLDDEAIRAMRDRFQLPISDADLPNIPFFKPSDDAPEMQYLHERRKALGGYLPQRRVQA 476 KKL DE I+A RDRF +PI D++LP +PF+KP+DD PEM+YLHERRKALGGYLP+RR +A Sbjct: 421 KKLIDEDIKAFRDRFNIPIPDSELPKLPFYKPADDTPEMRYLHERRKALGGYLPKRRAKA 480 Query: 477 DEKLPVPELSAFQAMLEPTAEGREISTTAAYSRVLTALLRDPNLGPRVVPIMVDESRTFG 536 DE VP L F+A+LEPTAEGREISTT AY R LT LLRD +GPRVVPI+VDE+RTFG Sbjct: 481 DESFTVPSLETFKAVLEPTAEGREISTTQAYVRFLTQLLRDQAIGPRVVPILVDEARTFG 540 Query: 537 MEGLFRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYST 596 MEGLFRQ+GI++ GQ Y PVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYST Sbjct: 541 MEGLFRQVGIYNPAGQNYTPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYST 600 Query: 597 NNRVMIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHV 656 +NR+MIPFY YYSMFG QRIGDLAWAAGDM+ARGFL+GGT+GRTTLNGEGLQHEDGHSH+ Sbjct: 601 SNRIMIPFYVYYSMFGFQRIGDLAWAAGDMQARGFLLGGTSGRTTLNGEGLQHEDGHSHI 660 Query: 657 FASAIPNCIPYDPTFAHEVAVIIHDGLRRMVANQEDVFYYITVMNENYGHPGIKPGQEEG 716 A IPNCI YDPTFAHEV VI+ GL+RMV QE+VFYY+T++NENY PG+K G EE Sbjct: 661 LAGTIPNCISYDPTFAHEVGVIMQHGLKRMVEKQENVFYYLTLLNENYPMPGLKAGTEEQ 720 Query: 717 IIKGLYLLNEG-GKQNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSFTLLAR 775 IIKG+YLL EG G RV LLGSGTILRE A LL DW V A+VWS PSF LAR Sbjct: 721 IIKGMYLLEEGQGAAGAPRVNLLGSGTILRESQFARQLLAQDWGVAANVWSCPSFNELAR 780 Query: 776 DGQDVERWNMLHPAEAPKKSYFEQSLEGSEGPIVVSTDYMRTYAEQVRAFVPKGRSYKVL 835 DGQD ER+N+LHP PK + Q L+ GP+V STDYM+ YA+Q+RAF+P+GRS+KVL Sbjct: 781 DGQDAERFNLLHPTATPKVPFVAQQLQPHIGPVVASTDYMKNYADQIRAFIPRGRSFKVL 840 Query: 836 GTDGYGRSDTRAKLREFFEVNRYFVTVAALKSLADEGKIKPEVVAQAIAKYGIDPNKPNP 895 GTDG+GRSD R+KLRE FE+NR+++ VAAL++LADEG + VVA+AIAKYGI +K NP Sbjct: 841 GTDGFGRSDFRSKLREHFEINRHYIVVAALRALADEGAVPTTVVAEAIAKYGIKADKINP 900 Query: 896 V 896 + Sbjct: 901 L 901 >C3XBK8.1 C3XBK8_OXAFO Pyruvate dehydrogenase E1 component EC=1.2.4.1 Length = 897 Score = 1378 bits (3566), Expect = 0.0, Method: Compositional matrix adjust. Identities = 640/884 (72%), Positives = 749/884 (84%) Query: 15 DPDVMETQEWLDALEAVIEKEGPDRAHYLMERMVDLARRRGAHIPFSSNTAYVNTIPADQ 74 DPD ET EWL+AL +VIE EG DRAHYLMER+ D+AR++G ++PFSSNTAY+NTIP D Sbjct: 14 DPDEQETSEWLEALHSVIESEGRDRAHYLMERLADVARQKGVNLPFSSNTAYINTIPPDL 73 Query: 75 GEHCPGNLEYEERLRSWMRWNAMAMVVKANRVDGDLGGHLSSFASLANMLGIGFNHFWHA 134 + PGN++YE RLR WMRWNAMAMVV+AN+ +LGGH++SF SLA M G GF+HFW A Sbjct: 74 QQGSPGNMDYEARLRGWMRWNAMAMVVRANKDGDNLGGHIASFTSLATMFGTGFHHFWRA 133 Query: 135 PTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREADGHGLSSYPHPKLMPEFW 194 PTE GDL+Y QGHSSPGIYARAFLEGRL+ +QL +FRRE G+GLSSYPHP+LMP+FW Sbjct: 134 PTETFDGDLVYFQGHSSPGIYARAFLEGRLSGEQLENFRREVHGNGLSSYPHPRLMPDFW 193 Query: 195 QFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCGDGEMDEPESMGAIGMAGR 254 QFPTVSMGLGP+MAIYQARFLKYL ARGIA T+ RKVW FCGDGEMDEPE+ GAI +A R Sbjct: 194 QFPTVSMGLGPIMAIYQARFLKYLQARGIADTEGRKVWVFCGDGEMDEPEAKGAISLASR 253 Query: 255 EKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNVVKVIWGSGWDELLAKDKD 314 E L+NL++V+NCNLQRLDGPVRGNGKIIQELE+DFRG+GWNV+KVIWGS WDELLA+DKD Sbjct: 254 ETLDNLIMVINCNLQRLDGPVRGNGKIIQELEADFRGSGWNVIKVIWGSDWDELLARDKD 313 Query: 315 GILQKVMMETVDGEYQNYKAKDGAYVRKHFFGKHPKLLEMVSKMSDDDIWRLTRGGHDPH 374 IL+KVMMETVDGEYQ YKAKDGAYVR+HFFGK P+LL+MV MSDD+IWRL+RGGHDP Sbjct: 314 NILKKVMMETVDGEYQTYKAKDGAYVREHFFGKDPRLLKMVENMSDDEIWRLSRGGHDPQ 373 Query: 375 KIYAAFKVAQESKDQPTVILAKSIKGYGFGKAGEARNTAHNTKKLDDEAIRAMRDRFQLP 434 K+YAAFKVAQE QPTVIL +++KGYG GKAGEA N AH KKLDD+ IR++RDR +P Sbjct: 374 KVYAAFKVAQEHTGQPTVILCQTVKGYGMGKAGEALNIAHQVKKLDDKTIRSLRDRAGVP 433 Query: 435 ISDADLPNIPFFKPSDDAPEMQYLHERRKALGGYLPQRRVQADEKLPVPELSAFQAMLEP 494 I D L +PF+ P +DAPEM YLHERRK LGGYLP RR +ADE L VP LSAFQA+LEP Sbjct: 434 IPDDKLDEVPFYMPPEDAPEMIYLHERRKLLGGYLPHRREKADEHLSVPPLSAFQAVLEP 493 Query: 495 TAEGREISTTAAYSRVLTALLRDPNLGPRVVPIMVDESRTFGMEGLFRQIGIFSQVGQLY 554 T GREISTT AY R L LLR ++G R+VPIMVDESRTFGMEGLFRQIGI++ GQLY Sbjct: 494 THPGREISTTQAYVRTLGILLRSTDIGRRIVPIMVDESRTFGMEGLFRQIGIYNPKGQLY 553 Query: 555 EPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYSTNNRVMIPFYTYYSMFGLQ 614 EPVD+D+VMYYREDKAGQILQEGI EAGG+ SWIAAATSYST+N++M+PFYTYYSMFG Q Sbjct: 554 EPVDQDEVMYYREDKAGQILQEGITEAGGICSWIAAATSYSTSNKIMLPFYTYYSMFGFQ 613 Query: 615 RIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHVFASAIPNCIPYDPTFAHE 674 R GDL WAA DM ARGFLIGGTAGRTTLNGEGLQHEDGH+HV A+ IPNC+PYDP FAHE Sbjct: 614 RTGDLMWAAADMMARGFLIGGTAGRTTLNGEGLQHEDGHNHVMAATIPNCLPYDPGFAHE 673 Query: 675 VAVIIHDGLRRMVANQEDVFYYITVMNENYGHPGIKPGQEEGIIKGLYLLNEGGKQNKLR 734 VAVII DG RRMV NQE+VFYY++VMNE+Y PG+KPGQEEGI+KG+YLL EG K R Sbjct: 674 VAVIIQDGARRMVENQENVFYYVSVMNESYPQPGMKPGQEEGILKGMYLLAEGEKDLPHR 733 Query: 735 VQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSFTLLARDGQDVERWNMLHPAEAPKK 794 VQLLGSGTI E+++A +LL++DWKV AD+WS SFTL+AR+G D+ERWNM+HP E PK Sbjct: 734 VQLLGSGTITHEMLSAVELLKNDWKVAADIWSVTSFTLVAREGNDIERWNMMHPGEEPKV 793 Query: 795 SYFEQSLEGSEGPIVVSTDYMRTYAEQVRAFVPKGRSYKVLGTDGYGRSDTRAKLREFFE 854 Y Q L+ ++GP++ STDY+R +AEQ+RA++P+GRSY VLGTDG+GRSDTRA LR FFE Sbjct: 794 PYATQCLKDTKGPVIASTDYIRLFAEQIRAYIPEGRSYTVLGTDGFGRSDTRANLRNFFE 853 Query: 855 VNRYFVTVAALKSLADEGKIKPEVVAQAIAKYGIDPNKPNPVTL 898 ++RY+VTVAAL++LA G I E V++AI KYGI+ KPNPV L Sbjct: 854 IDRYYVTVAALEALARSGDIPAETVSKAIEKYGINREKPNPVDL 897 >C3X5D4.1 C3X5D4_OXAFO Pyruvate dehydrogenase E1 component EC=1.2.4.1 Length = 897 Score = 1375 bits (3558), Expect = 0.0, Method: Compositional matrix adjust. Identities = 643/898 (71%), Positives = 745/898 (82%), Gaps = 1/898 (0%) Query: 1 MSAQIDQVLAQAANDPDVMETQEWLDALEAVIEKEGPDRAHYLMERMVDLARRRGAHIPF 60 M++Q D V D D ET EWLDAL AVIE EGP+RAHYLMER+ D+AR++G ++PF Sbjct: 1 MASQQDDVFIHY-QDRDERETSEWLDALHAVIENEGPERAHYLMERLADVARQKGVNLPF 59 Query: 61 SSNTAYVNTIPADQGEHCPGNLEYEERLRSWMRWNAMAMVVKANRVDGDLGGHLSSFASL 120 SSNTAY+NTIP ++ + PGN+ YE RLR+WMRWNAMAMVV+ANR +LGGH++SF S+ Sbjct: 60 SSNTAYINTIPPEREQRSPGNMAYEARLRAWMRWNAMAMVVRANREGDNLGGHIASFTSV 119 Query: 121 ANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREADGHG 180 A M G GFNHFW APTE GDL+Y QGHSSPG+YARAF+EGRLTE+QL +FRRE G+G Sbjct: 120 ATMFGTGFNHFWRAPTETFDGDLVYFQGHSSPGVYARAFIEGRLTEEQLENFRREVHGNG 179 Query: 181 LSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCGDGEM 240 LSSYPHPKLMP+FWQFPTVSMGLGP+MAIYQARFLKYL ARGIA T RKVW FCGDGEM Sbjct: 180 LSSYPHPKLMPDFWQFPTVSMGLGPIMAIYQARFLKYLQARGIADTAGRKVWVFCGDGEM 239 Query: 241 DEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNVVKVI 300 DEPE+ GAI +A RE L+NL++VVNCNLQRLDGPVRGNGKIIQELE+DFRGAGWNV+KVI Sbjct: 240 DEPEAKGAISLASRESLDNLIMVVNCNLQRLDGPVRGNGKIIQELEADFRGAGWNVIKVI 299 Query: 301 WGSGWDELLAKDKDGILQKVMMETVDGEYQNYKAKDGAYVRKHFFGKHPKLLEMVSKMSD 360 WGS WDELLA+DKD IL+KVMMETVDGEYQ+YKA+DGAYVRKHFFGK P+LL+MV MSD Sbjct: 300 WGSDWDELLARDKDNILKKVMMETVDGEYQSYKARDGAYVRKHFFGKDPRLLKMVENMSD 359 Query: 361 DDIWRLTRGGHDPHKIYAAFKVAQESKDQPTVILAKSIKGYGFGKAGEARNTAHNTKKLD 420 D++WRL+RGGHDP K+YAAFK AQE QPT+IL +++KGYG GKAGEA N AH KKLD Sbjct: 360 DELWRLSRGGHDPQKVYAAFKAAQEHTGQPTIILCQTVKGYGMGKAGEALNIAHQVKKLD 419 Query: 421 DEAIRAMRDRFQLPISDADLPNIPFFKPSDDAPEMQYLHERRKALGGYLPQRRVQADEKL 480 D+ IR +RDR +PI D L +IPF++P +DAPEM YL E RKALGGYLP RR +ADE L Sbjct: 420 DKTIRTLRDRAGVPIPDDRLDDIPFYRPPEDAPEMIYLRECRKALGGYLPHRRQKADEYL 479 Query: 481 PVPELSAFQAMLEPTAEGREISTTAAYSRVLTALLRDPNLGPRVVPIMVDESRTFGMEGL 540 PVP LSAF A+LEPT GR ISTT AY R L LLR P +G R+VPIMVDESRTFGMEGL Sbjct: 480 PVPPLSAFSALLEPTHPGRSISTTQAYVRALGILLRAPEIGRRIVPIMVDESRTFGMEGL 539 Query: 541 FRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYSTNNRV 600 FRQIGI++ GQLYEPVD D+VMYYREDK GQILQEGI EAGGM SWIAAATSYS +NR+ Sbjct: 540 FRQIGIYNPKGQLYEPVDSDEVMYYREDKTGQILQEGITEAGGMCSWIAAATSYSVSNRI 599 Query: 601 MIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHVFASA 660 M+PFYTYYSMFG QR GDL WAA DM ARGFLIGGTAGRTTLNGEGLQHEDG +HVFA+ Sbjct: 600 MLPFYTYYSMFGFQRTGDLMWAAADMMARGFLIGGTAGRTTLNGEGLQHEDGQNHVFAAT 659 Query: 661 IPNCIPYDPTFAHEVAVIIHDGLRRMVANQEDVFYYITVMNENYGHPGIKPGQEEGIIKG 720 IP C PYDP FAHEVAVII DG RRMV QEDVFYYI+VMNE+Y PGIKPGQEEGI+KG Sbjct: 660 IPTCRPYDPGFAHEVAVIIQDGARRMVEEQEDVFYYISVMNESYPQPGIKPGQEEGILKG 719 Query: 721 LYLLNEGGKQNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPSFTLLARDGQDV 780 +YLL EG K RVQLLGSGTI E+++A DLL+DDW V AD+WS SFT++AR+G D Sbjct: 720 MYLLQEGEKNLPHRVQLLGSGTITHEMLSAVDLLKDDWNVAADIWSVTSFTMVAREGNDA 779 Query: 781 ERWNMLHPAEAPKKSYFEQSLEGSEGPIVVSTDYMRTYAEQVRAFVPKGRSYKVLGTDGY 840 ERWNM+HP E P+ Y + L+ + GPI+ STDY+R +AEQ+RA++P+GRSY VLGTDG+ Sbjct: 780 ERWNMMHPGETPRVPYATECLKSTAGPIIASTDYVRLFAEQIRAYIPEGRSYTVLGTDGF 839 Query: 841 GRSDTRAKLREFFEVNRYFVTVAALKSLADEGKIKPEVVAQAIAKYGIDPNKPNPVTL 898 GRSDTRA LR FFE++RY+VT+AAL++LA G I E V++AI KY ID KPNPV + Sbjct: 840 GRSDTRANLRHFFEIDRYYVTLAALEALAKTGDIPAETVSEAIEKYRIDREKPNPVDM 897 >E6V0W8.1 E6V0W8_VARPD Pyruvate dehydrogenase E1 component EC=1.2.4.1 Length = 909 Score = 1370 bits (3547), Expect = 0.0, Method: Compositional matrix adjust. Identities = 632/907 (69%), Positives = 751/907 (82%), Gaps = 11/907 (1%) Query: 1 MSAQIDQVLAQAANDPDVMETQEWLDALEAVIEKEGPDRAHYLMERMVDLARRRGAHIPF 60 MSA + + AAND D ET+EW+DAL +VI+ EGP+RAH+L+E++++ AR+ PF Sbjct: 1 MSANPENLFGSAANDADAQETREWMDALSSVIQSEGPERAHFLLEQLLEHARQHSIDKPF 60 Query: 61 SSNTAYVNTIPADQGEHCPGNLEYEERLRSWMRWNAMAMVVKANR----VDGDLGGHLSS 116 S+NTAYVNTI DQ E CPGNLE EERLR++MRWNAMAMVVKANR GDLGGH+ S Sbjct: 61 SANTAYVNTIEPDQEERCPGNLEIEERLRAYMRWNAMAMVVKANRHHPPEGGDLGGHIGS 120 Query: 117 FASLANMLGIGFNHFWHAPTEDHGGDLLYIQGHSSPGIYARAFLEGRLTEDQLIHFRREA 176 FASLANM G GFNHFWHA +E+HGGD LYIQGH SPGIYARA+LEGRLTE+QL++FR+E Sbjct: 121 FASLANMFGAGFNHFWHAESENHGGDCLYIQGHVSPGIYARAYLEGRLTEEQLLNFRQEV 180 Query: 177 DGHGLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIAKTDNRKVWAFCG 236 DG GLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIA T+NRKVW FCG Sbjct: 181 DGKGLSSYPHPKLMPEFWQFPTVSMGLGPLMAIYQARFLKYLHARGIANTENRKVWVFCG 240 Query: 237 DGEMDEPESMGAIGMAGREKLNNLVIVVNCNLQRLDGPVRGNGKIIQELESDFRGAGWNV 296 DGEMDE ESMGAIG+A RE L+NLV V+NCNLQRLDGPVRGNGKIIQELE +FRG+GWNV Sbjct: 241 DGEMDEVESMGAIGLAAREGLDNLVFVINCNLQRLDGPVRGNGKIIQELEGEFRGSGWNV 300 Query: 297 VKVIWGSGWDELLAKDKDGILQKVMMETVDGEYQNYKAKDGAYVRKHFFGKHPKLLEMVS 356 +K+IWGSGWD+L+A+DK+G L+K+MMET DG+YQ++KA DGAYVRKHFFG+ P+ LEMV+ Sbjct: 301 IKLIWGSGWDQLIARDKEGALRKIMMETNDGDYQSFKANDGAYVRKHFFGRDPRTLEMVA 360 Query: 357 KMSDDDIWRLTRGGHDPHKIYAAFKVAQESKDQPTVILAKSIKGYGFGKAGEARNTAHNT 416 KMSDDDIW+L RGGHD K+YAAF A + K QPTV+L K++KG+G GK GE +N H T Sbjct: 361 KMSDDDIWQLRRGGHDSQKVYAAFDAAVKHKGQPTVLLIKTVKGFGMGKIGEGKNNVHQT 420 Query: 417 KKLDDEAIRAMRDRFQLPISDADLPNIPFFKPSDDAPEMQYLHERRKALGGYLPQRRVQA 476 KKL DE I A RDRF +PI D+ + ++PF+KP+DD PEM+YLHERRKALGGYLP RR +A Sbjct: 421 KKLSDEDIMAFRDRFNIPIPDSQIADLPFYKPADDTPEMKYLHERRKALGGYLPHRRTKA 480 Query: 477 DEKLPVPELSAFQAMLEPTAEGREISTTAAYSRVLTALLRDPNLGPRVVPIMVDESRTFG 536 DE VP L F++++EPTAEGREISTT AY R LT LLRD LGPRVVPI+VDE+RTFG Sbjct: 481 DESFTVPSLETFKSVMEPTAEGREISTTQAYVRFLTQLLRDKALGPRVVPILVDEARTFG 540 Query: 537 MEGLFRQIGIFSQVGQLYEPVDKDQVMYYREDKAGQILQEGINEAGGMSSWIAAATSYST 596 MEGLFRQIGI++ GQ Y PVDKDQVMYY+EDKAGQILQEGINEAGGMSSWIAAATSYST Sbjct: 541 MEGLFRQIGIYNPAGQQYTPVDKDQVMYYKEDKAGQILQEGINEAGGMSSWIAAATSYST 600 Query: 597 NNRVMIPFYTYYSMFGLQRIGDLAWAAGDMRARGFLIGGTAGRTTLNGEGLQHEDGHSHV 656 NNR+M+PFY YYSMFG QRIGDLAWAAGDM+ARGFL+GGT+GRTTLNGEGLQHEDGHSH+ Sbjct: 601 NNRIMVPFYVYYSMFGFQRIGDLAWAAGDMQARGFLLGGTSGRTTLNGEGLQHEDGHSHI 660 Query: 657 FASAIPNCIPYDPTFAHEVAVIIHDGLRRMVANQEDVFYYITVMNENYGHPGIKPGQEEG 716 A+ IPNC+ YDPTFAHEV VI+H GL+RMV Q++V+YY+T++NENY PG++PG EE Sbjct: 661 LANTIPNCVSYDPTFAHEVGVILHHGLKRMVEKQDNVYYYLTLLNENYAMPGLQPGTEEQ 720 Query: 717 IIKGLYLLNEG-------GKQNKLRVQLLGSGTILREVIAAADLLRDDWKVDADVWSAPS 769 IIKG+YL +G G + VQLLGSGTILRE AA +LL DW V A VWS PS Sbjct: 721 IIKGMYLSKQGPVVKAAKGSKEAPTVQLLGSGTILRESFAAQELLEKDWGVSASVWSCPS 780 Query: 770 FTLLARDGQDVERWNMLHPAEAPKKSYFEQSLEGSEGPIVVSTDYMRTYAEQVRAFVPKG 829 F L RDGQD +RWN+LHP + P+ + + L + GP+V STDYM+ YAEQ+R F+PKG Sbjct: 781 FNELTRDGQDADRWNLLHPDQTPRVPFVAEQLAPTTGPVVASTDYMKAYAEQIRPFIPKG 840 Query: 830 RSYKVLGTDGYGRSDTRAKLREFFEVNRYFVTVAALKSLADEGKIKPEVVAQAIAKYGID 889 R+YKVLGTDG+GRSD R KLRE FE+NR+++ VAALK+L+++G + V +AI KYGI+ Sbjct: 841 RTYKVLGTDGFGRSDFRNKLREHFEINRHYIVVAALKALSEDGTVPVAKVVEAIKKYGIN 900 Query: 890 PNKPNPV 896 +K NP+ Sbjct: 901 VDKVNPL 907