BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0100.p (537 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IPE8.1 D8IPE8_HERSS Glutamate--cysteine ligase EC=6.3.2.2 1087 0.0 A6SX59.1 GSH1_JANMA Glutamate--cysteine ligase EC=6.3.2.2 680 0.0 C3KE56.1 C3KE56_PSEFS Glutamate--cysteine ligase EC=6.3.2.2 659 0.0 Q3KJQ5.1 GSH1_PSEPF Glutamate--cysteine ligase EC=6.3.2.2 654 0.0 C1DJH1.1 GSH1_AZOVD Glutamate--cysteine ligase EC=6.3.2.2 653 0.0 E2XJU8.1 E2XJU8_PSEFL Glutamate--cysteine ligase EC=6.3.2.2 653 0.0 A4G406.1 A4G406_HERAR Glutamate--cysteine ligase EC=6.3.2.2 650 0.0 F2KAR1.1 F2KAR1_PSEBR Glutamate--cysteine ligase 649 0.0 B0KHZ5.1 B0KHZ5_PSEPG Glutamate--cysteine ligase EC=6.3.2.2 648 0.0 A6VDX9.1 GSH1_PSEA7 Glutamate--cysteine ligase EC=6.3.2.2 644 0.0 >D8IPE8.1 D8IPE8_HERSS Glutamate--cysteine ligase EC=6.3.2.2 Length = 531 Score = 1087 bits (2811), Expect = 0.0, Method: Compositional matrix adjust. Identities = 529/531 (99%), Positives = 530/531 (99%) Query: 7 MTDLLNRRLQQLSQPQHLALLGQGLRGIERETLRVDAQGHLARTPHPPALGSALTNELIT 66 MTDLLNRRLQQLSQPQHLALLGQGLRGIERETLRVDAQGHLARTPHPPALGSALTNELIT Sbjct: 1 MTDLLNRRLQQLSQPQHLALLGQGLRGIERETLRVDAQGHLARTPHPPALGSALTNELIT 60 Query: 67 TDYSEALLEFITPAMPDIADALQRLDEIHRFAYAKLEGEFLWNASMPCVLPPEDEIPIAW 126 TDYSEALLEFITPAMPDIADALQRLDEIHRFAYAKLEGEFLWNASMPCVLPPEDEIPIAW Sbjct: 61 TDYSEALLEFITPAMPDIADALQRLDEIHRFAYAKLEGEFLWNASMPCVLPPEDEIPIAW 120 Query: 127 YGNSHIGMLKHVYRRGLALRYGRTMQCIAGIHYNFSLSEDLWEVLREGDDSVDLSLSRRD 186 YGNSHIGMLKHVYRRGLALRYGRTMQCIAGIHYNFSLSEDLWEVLREGDDSVDLSLSRRD Sbjct: 121 YGNSHIGMLKHVYRRGLALRYGRTMQCIAGIHYNFSLSEDLWEVLREGDDSVDLSLSRRD 180 Query: 187 YQSERYIALIRNFRRYSWLLMYLFGASPAVATNFLRGRPHQLETLSEDTLYLPYGTSLRM 246 YQSERYIALIRNFRRYSWLLMYLFGASPAVATNFLRGRPHQLETLSEDTLYLPYGTSLRM Sbjct: 181 YQSERYIALIRNFRRYSWLLMYLFGASPAVATNFLRGRPHQLETLSEDTLYLPYGTSLRM 240 Query: 247 SDLGYQNHAQANITPHYNNLPAYIRSLSHAVSEPYPPYEAIGTKRDGQWVQINTNILQIE 306 SDLGYQNHAQANITPHYNNLPAYIRSLSHAVSEPYPPYEAIGTKRDGQWVQINTNILQIE Sbjct: 241 SDLGYQNHAQANITPHYNNLPAYIRSLSHAVSEPYPPYEAIGTKRDGQWVQINTNILQIE 300 Query: 307 NEFYSSIRPKRVINSGERPVQALSARGVQYVEVRCMDIDPFNPLGIGLEAARFLDVFLHF 366 NEFYSSIRPKRVINSGERPVQALSARGVQYVEVRCMDIDPFNPLGIGLEAARFLDVFLHF Sbjct: 301 NEFYSSIRPKRVINSGERPVQALSARGVQYVEVRCMDIDPFNPLGIGLEAARFLDVFLHF 360 Query: 367 LALESSCLTSDEEGAENRANFLATVKEGRRPGLQLHFKGATIGLKEWGEQLLDRMAPVAD 426 LALESSCLTSDEEGAENRANFLATVKEGRRPGLQLHFKGA+IGLK WGEQLLDRMAPVAD Sbjct: 361 LALESSCLTSDEEGAENRANFLATVKEGRRPGLQLHFKGASIGLKAWGEQLLDRMAPVAD 420 Query: 427 LLDRQRGGSQHRDSLQAQRAKLADPDSTPSARVLREIRASGNSFADYTLASSQRQAAELM 486 LLDRQRGGSQHRDSLQAQRAKLADPDSTPSARVLREIRASGNSFADYTLASSQRQAAELM Sbjct: 421 LLDRQRGGSQHRDSLQAQRAKLADPDSTPSARVLREIRASGNSFADYTLASSQRQAAELM 480 Query: 487 ARPLPAATTADFVAIAQASLDAQRAIERTQEGDFDTFVAAYRASTLGNIAI 537 ARPLPAATTADFVAIAQASLDAQRAIERTQEGDFDTFVAAYRASTLGNIAI Sbjct: 481 ARPLPAATTADFVAIAQASLDAQRAIERTQEGDFDTFVAAYRASTLGNIAI 531 >A6SX59.1 GSH1_JANMA Glutamate--cysteine ligase EC=6.3.2.2 Length = 528 Score = 680 bits (1755), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/525 (63%), Positives = 397/525 (75%), Gaps = 3/525 (0%) Query: 7 MTDLLNRRLQQLSQPQHLALLGQGLRGIERETLRVDAQGHLARTPHPPALGSALTNELIT 66 M++L RRL L+ H LL QG RGIERETLRVD QG LA PHP ALGSALTN IT Sbjct: 1 MSNLFTRRLALLADDAHRDLLNQGRRGIERETLRVDLQGKLALGPHPVALGSALTNPQIT 60 Query: 67 TDYSEALLEFITPAMPDIADALQRLDEIHRFAYAKLEGEFLWNASMPCVLPPEDEIPIAW 126 TDYSE+LLEFITPA D+A AL+ LD IHRFA AKL+ E LW+ SMPC LP E +IPIAW Sbjct: 61 TDYSESLLEFITPAEHDVATALEELDRIHRFANAKLDHELLWSQSMPCTLPEEADIPIAW 120 Query: 127 YGNSHIGMLKHVYRRGLALRYGRTMQCIAGIHYNFSLSEDLWEVLREGDDSVDLSLSRRD 186 YG SHIGM+KHVYRRGLALRYG+ MQCIAG+HYN+SLSEDLW V+++ + S L + Sbjct: 121 YGTSHIGMIKHVYRRGLALRYGKAMQCIAGLHYNYSLSEDLWRVIKQSEQS---RLDDKS 177 Query: 187 YQSERYIALIRNFRRYSWLLMYLFGASPAVATNFLRGRPHQLETLSEDTLYLPYGTSLRM 246 YQSE YI+LIRNF+RYSWLLMYLFGASPA++T+FLRGR H+L+TLS+DTLYLPY TSLRM Sbjct: 178 YQSESYISLIRNFQRYSWLLMYLFGASPALSTHFLRGREHELQTLSDDTLYLPYATSLRM 237 Query: 247 SDLGYQNHAQANITPHYNNLPAYIRSLSHAVSEPYPPYEAIGTKRDGQWVQINTNILQIE 306 SDLGYQN+AQA + P YN+L +Y+RSLS AV + YP YEAIGT+R+G+W+Q+NTN+LQIE Sbjct: 238 SDLGYQNNAQAGLMPPYNDLESYMRSLSRAVRQAYPAYEAIGTRRNGEWIQLNTNLLQIE 297 Query: 307 NEFYSSIRPKRVINSGERPVQALSARGVQYVEVRCMDIDPFNPLGIGLEAARFLDVFLHF 366 NE+Y++IRPKRVINSGERPV+AL ARGVQY+EVRCMDIDPF PLGI L +RFLD FL F Sbjct: 298 NEYYATIRPKRVINSGERPVEALCARGVQYIEVRCMDIDPFEPLGISLPTSRFLDAFLLF 357 Query: 367 LALESSCLTSDEEGAENRANFLATVKEGRRPGLQLHFKGATIGLKEWGEQLLDRMAPVAD 426 AL+ S LT + E NF TVKEGRRPGL L GA + L++WG +LL+R+ AD Sbjct: 358 CALDDSPLTDEANNRERTENFARTVKEGRRPGLLLQRDGAAVKLQDWGLELLERIQATAD 417 Query: 427 LLDRQRGGSQHRDSLQAQRAKLADPDSTPSARVLREIRASGNSFADYTLASSQRQAAELM 486 LLD QR SQH +L AQ+ KL D TPSARVL E++A+ SF + L S A Sbjct: 418 LLDAQRADSQHAQALAAQKEKLLDAGLTPSARVLAELQATDKSFEQFGLRQSIAHAEYFR 477 Query: 487 ARPLPAATTADFVAIAQASLDAQRAIERTQEGDFDTFVAAYRAST 531 ARPL A F +A+ S+ Q +ERTQ GDFD FV AY T Sbjct: 478 ARPLNAEENFYFETLAKTSIAEQEEMERTQSGDFDAFVEAYNQRT 522 >C3KE56.1 C3KE56_PSEFS Glutamate--cysteine ligase EC=6.3.2.2 Length = 527 Score = 659 bits (1699), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/527 (60%), Positives = 394/527 (74%), Gaps = 3/527 (0%) Query: 7 MTDLLNRRLQQLSQPQHLALLGQGLRGIERETLRVDAQGHLARTPHPPALGSALTNELIT 66 M++LLNRRL L + +HL+LL Q L GIERE LRV +G LA+TPHP ALG+ALTNELIT Sbjct: 1 MSELLNRRLALLGKREHLSLLEQCLHGIERECLRVTGEGRLAQTPHPEALGAALTNELIT 60 Query: 67 TDYSEALLEFITPAMPDIADALQRLDEIHRFAYAKLEGEFLWNASMPCVLPPEDEIPIAW 126 TDYSE+LLEFITPA+P+ AD L LD+IHRFAY KL E+LW+ SMPC LP E++IPIA+ Sbjct: 61 TDYSESLLEFITPALPNPADTLSSLDKIHRFAYTKLGSEYLWSPSMPCPLPAEEDIPIAY 120 Query: 127 YGNSHIGMLKHVYRRGLALRYGRTMQCIAGIHYNFSLSEDLWEVLREGDDSVDLSLSRRD 186 YG S+IG LK+VYR+GLALRYG+TMQCIAGIHYNFSL E LW +L+E + V + RD Sbjct: 121 YGTSNIGQLKYVYRKGLALRYGKTMQCIAGIHYNFSLPEALWPLLKETEGFVG---TDRD 177 Query: 187 YQSERYIALIRNFRRYSWLLMYLFGASPAVATNFLRGRPHQLETLSEDTLYLPYGTSLRM 246 YQS YIALIRNFRRYSWLLMYLFGASPA+ FLRGR HQLE L DTLYLPY TSLRM Sbjct: 178 YQSTAYIALIRNFRRYSWLLMYLFGASPALDAGFLRGRSHQLEVLDADTLYLPYATSLRM 237 Query: 247 SDLGYQNHAQANITPHYNNLPAYIRSLSHAVSEPYPPYEAIGTKRDGQWVQINTNILQIE 306 SDLGYQ++AQA +TP YN+L +Y SL AV+ PY PY +GT +DG+WVQ+NTNILQIE Sbjct: 238 SDLGYQSNAQAGLTPCYNDLASYTDSLREAVATPYAPYVEVGTHKDGEWVQLNTNILQIE 297 Query: 307 NEFYSSIRPKRVINSGERPVQALSARGVQYVEVRCMDIDPFNPLGIGLEAARFLDVFLHF 366 NE+YS+IRPKRV +GERP+QAL ARG+QY+EVRC+DI+PF P+GI L +RFLD FL + Sbjct: 298 NEYYSNIRPKRVTYTGERPIQALVARGIQYIEVRCLDINPFLPMGIDLPESRFLDAFLLY 357 Query: 367 LALESSCLTSDEEGAENRANFLATVKEGRRPGLQLHFKGATIGLKEWGEQLLDRMAPVAD 426 AL S L +D E +NFL+ VKEGRRPGLQL +G + +KEW +LL+++AP+A Sbjct: 358 CALNDSPLFADNECGNATSNFLSVVKEGRRPGLQLQRQGQAVDMKEWAAELLEQIAPLAA 417 Query: 427 LLDRQRGGSQHRDSLQAQRAKLADPDSTPSARVLREIRASGNSFADYTLASSQRQAAELM 486 LLD G ++H +L AQ AK+ DP TPSA+VL + SFA ++L SQ A Sbjct: 418 LLDESHGITEHSQALDAQLAKVKDPSLTPSAQVLAAMAERKESFAQFSLHQSQLHAEHFR 477 Query: 487 ARPLPAATTADFVAIAQASLDAQRAIERTQEGDFDTFVAAYRASTLG 533 PLPA F +A+ SL Q +E+ + GDFD FV +Y+AS L Sbjct: 478 KEPLPAEEQTRFEQLARTSLAQQAELEQNEVGDFDVFVGSYQASILA 524 >Q3KJQ5.1 GSH1_PSEPF Glutamate--cysteine ligase EC=6.3.2.2 Length = 532 Score = 654 bits (1688), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/531 (60%), Positives = 396/531 (74%), Gaps = 3/531 (0%) Query: 3 KDYRMTDLLNRRLQQLSQPQHLALLGQGLRGIERETLRVDAQGHLARTPHPPALGSALTN 62 K+ ++++LLNRRL L + +L+LL Q L GIERE LRV +G LA+TPHP ALGSALTN Sbjct: 2 KESKLSELLNRRLALLGERANLSLLEQCLHGIERECLRVTGEGRLAQTPHPEALGSALTN 61 Query: 63 ELITTDYSEALLEFITPAMPDIADALQRLDEIHRFAYAKLEGEFLWNASMPCVLPPEDEI 122 E ITTDYSE+LLEFITPA+PD AD L LD+IHRFAY+KL E+LW+ SMPC LP E++I Sbjct: 62 EQITTDYSESLLEFITPALPDPADTLASLDKIHRFAYSKLGNEYLWSPSMPCPLPAEEDI 121 Query: 123 PIAWYGNSHIGMLKHVYRRGLALRYGRTMQCIAGIHYNFSLSEDLWEVLREGDDSVDLSL 182 PIA+YG S+IG LK+VYR+GLALRYG+TMQCIAGIHYNFSL E LW +L+E + V Sbjct: 122 PIAYYGTSNIGQLKYVYRKGLALRYGKTMQCIAGIHYNFSLPEKLWPLLKEAEGFVG--- 178 Query: 183 SRRDYQSERYIALIRNFRRYSWLLMYLFGASPAVATNFLRGRPHQLETLSEDTLYLPYGT 242 + RD+QS YIALIRNFRRYSWLLMYLFGASPA+ FLRGR HQLE L DTLYLPY T Sbjct: 179 TDRDFQSSSYIALIRNFRRYSWLLMYLFGASPALDAGFLRGRAHQLEQLDPDTLYLPYAT 238 Query: 243 SLRMSDLGYQNHAQANITPHYNNLPAYIRSLSHAVSEPYPPYEAIGTKRDGQWVQINTNI 302 SLRMSDLGYQ++AQA +TP YN+L +Y SL AV+ PY PY +GT +DG+WVQ+NTNI Sbjct: 239 SLRMSDLGYQSNAQAGLTPCYNDLASYTDSLRKAVATPYAPYVEVGTHQDGEWVQLNTNI 298 Query: 303 LQIENEFYSSIRPKRVINSGERPVQALSARGVQYVEVRCMDIDPFNPLGIGLEAARFLDV 362 LQIENE+YS+IRPKRV +GERP+QAL ARG+QYVEVRC+DI+PF P+GI L +RFLD Sbjct: 299 LQIENEYYSNIRPKRVTYTGERPIQALMARGIQYVEVRCLDINPFLPMGIDLTESRFLDA 358 Query: 363 FLHFLALESSCLTSDEEGAENRANFLATVKEGRRPGLQLHFKGATIGLKEWGEQLLDRMA 422 FL + AL S L ++ +NFL+ VKEGRRPGLQL G + LKEW +LL+++A Sbjct: 359 FLLYCALNESPLLTNNSCGNATSNFLSVVKEGRRPGLQLQRDGQPVELKEWAAELLEKIA 418 Query: 423 PVADLLDRQRGGSQHRDSLQAQRAKLADPDSTPSARVLREIRASGNSFADYTLASSQRQA 482 P+A LLD+ GG H +L AQ AK+ D TPSA+VL + A SFA ++L SQ A Sbjct: 419 PLAALLDQSHGGDAHSKALDAQLAKVKDSSLTPSAQVLAAMAAHKESFAQFSLRQSQAHA 478 Query: 483 AELMARPLPAATTADFVAIAQASLDAQRAIERTQEGDFDTFVAAYRASTLG 533 + PL A A F +A++SL Q +E+ + GDFD FV +Y+AS L Sbjct: 479 EFFRSEPLAAEEQAKFEELARSSLAQQAELEQNEVGDFDVFVGSYQASILA 529 >C1DJH1.1 GSH1_AZOVD Glutamate--cysteine ligase EC=6.3.2.2 Length = 530 Score = 653 bits (1685), Expect = 0.0, Method: Compositional matrix adjust. Identities = 330/528 (62%), Positives = 389/528 (73%) Query: 7 MTDLLNRRLQQLSQPQHLALLGQGLRGIERETLRVDAQGHLARTPHPPALGSALTNELIT 66 M++L +RRL L +P + +LL L GIERE LRVDA G LARTPHP ALGSALT+ IT Sbjct: 1 MSELFSRRLALLGEPANQSLLRHCLHGIERECLRVDAAGELARTPHPAALGSALTHPYIT 60 Query: 67 TDYSEALLEFITPAMPDIADALQRLDEIHRFAYAKLEGEFLWNASMPCVLPPEDEIPIAW 126 TDYSEALLEFITPA D A L L+ +HRFA AKL+GE+LW+ SMPC LP E++IPIA Sbjct: 61 TDYSEALLEFITPAETDSAATLAALERVHRFACAKLDGEYLWSPSMPCPLPAEEDIPIAR 120 Query: 127 YGNSHIGMLKHVYRRGLALRYGRTMQCIAGIHYNFSLSEDLWEVLREGDDSVDLSLSRRD 186 YGNSHIG LKHVYR+GLALRYG+TMQCIAGIHYNFSL E+LW +L+ + V RD Sbjct: 121 YGNSHIGRLKHVYRKGLALRYGKTMQCIAGIHYNFSLPEELWPLLQRAEGDVRGVRGVRD 180 Query: 187 YQSERYIALIRNFRRYSWLLMYLFGASPAVATNFLRGRPHQLETLSEDTLYLPYGTSLRM 246 +QSERYIALIRNFRRYSWLLMYLFGASPA+ +FLRGRPH L+ L +TLYLP+ TSLRM Sbjct: 181 FQSERYIALIRNFRRYSWLLMYLFGASPALDKSFLRGRPHHLQELDAETLYLPWATSLRM 240 Query: 247 SDLGYQNHAQANITPHYNNLPAYIRSLSHAVSEPYPPYEAIGTKRDGQWVQINTNILQIE 306 SDLGY N+AQA++TP YN+L +Y SL AVS PY PY AIGT+RDG+W+Q+NTN+LQIE Sbjct: 241 SDLGYHNNAQADLTPCYNDLASYTDSLRRAVSTPYAPYAAIGTQRDGEWLQLNTNVLQIE 300 Query: 307 NEFYSSIRPKRVINSGERPVQALSARGVQYVEVRCMDIDPFNPLGIGLEAARFLDVFLHF 366 NE+YS+IRPKRV SGERP+QAL ARGVQYVEVRC+DIDPF PLGI L+ ARFLD FL F Sbjct: 301 NEYYSTIRPKRVTASGERPIQALVARGVQYVEVRCLDIDPFLPLGIDLDEARFLDAFLLF 360 Query: 367 LALESSCLTSDEEGAENRANFLATVKEGRRPGLQLHFKGATIGLKEWGEQLLDRMAPVAD 426 ALE S + E A NFL VKEGRRPGL L G + L W +LL+R+ P+A Sbjct: 361 CALEDSPCLAAGECASCTGNFLKVVKEGRRPGLHLQRHGQPMPLAAWAGELLERLQPLAA 420 Query: 427 LLDRQRGGSQHRDSLQAQRAKLADPDSTPSARVLREIRASGNSFADYTLASSQRQAAELM 486 L DR GG + +L AQ+AK+ADP+ TPSAR+L +R G SF + L S A L Sbjct: 421 LFDRAYGGDGYEKALHAQQAKVADPELTPSARLLATLRERGESFRAFALRQSLAHAESLR 480 Query: 487 ARPLPAATTADFVAIAQASLDAQRAIERTQEGDFDTFVAAYRASTLGN 534 ARPL F A A+ASL Q +ER G FD FVAAY+AS G+ Sbjct: 481 ARPLGEEERQAFEAEARASLAEQAELERRDTGSFDDFVAAYQASIQGD 528 >E2XJU8.1 E2XJU8_PSEFL Glutamate--cysteine ligase EC=6.3.2.2 Length = 532 Score = 653 bits (1685), Expect = 0.0, Method: Compositional matrix adjust. Identities = 318/531 (59%), Positives = 397/531 (74%), Gaps = 3/531 (0%) Query: 3 KDYRMTDLLNRRLQQLSQPQHLALLGQGLRGIERETLRVDAQGHLARTPHPPALGSALTN 62 K+ +++LLNRRL L + +HL+LL L GIERE LRV +G LA+TPHP ALG+ALTN Sbjct: 2 KESNLSELLNRRLALLGKREHLSLLEHCLHGIERECLRVTGEGRLAQTPHPEALGAALTN 61 Query: 63 ELITTDYSEALLEFITPAMPDIADALQRLDEIHRFAYAKLEGEFLWNASMPCVLPPEDEI 122 ELITTDYSE+LLEFITPA+P+ AD L LD+IHRFAY+KL E+LW+ SMPC LP E++I Sbjct: 62 ELITTDYSESLLEFITPALPNPADTLSSLDKIHRFAYSKLGSEYLWSPSMPCPLPAEEDI 121 Query: 123 PIAWYGNSHIGMLKHVYRRGLALRYGRTMQCIAGIHYNFSLSEDLWEVLREGDDSVDLSL 182 PIA+YG S+IG LK+VYR+GLALRYG+TMQCIAGIHYNFSL E LW +L+E + V Sbjct: 122 PIAYYGTSNIGQLKYVYRKGLALRYGKTMQCIAGIHYNFSLPETLWPLLKETEGFVG--- 178 Query: 183 SRRDYQSERYIALIRNFRRYSWLLMYLFGASPAVATNFLRGRPHQLETLSEDTLYLPYGT 242 + RDYQS YIALIRNFRRYSWLLMYLFGASPA+ FLRGR HQLE L DTLYLPY T Sbjct: 179 TDRDYQSNAYIALIRNFRRYSWLLMYLFGASPALDAGFLRGRSHQLEVLDADTLYLPYAT 238 Query: 243 SLRMSDLGYQNHAQANITPHYNNLPAYIRSLSHAVSEPYPPYEAIGTKRDGQWVQINTNI 302 SLRMSDLGYQ++AQA +TP YN+L +Y SL AV+ PY PY +GT +DG+WVQ+NTNI Sbjct: 239 SLRMSDLGYQSNAQAGLTPCYNDLASYTDSLREAVATPYAPYVEVGTHKDGEWVQLNTNI 298 Query: 303 LQIENEFYSSIRPKRVINSGERPVQALSARGVQYVEVRCMDIDPFNPLGIGLEAARFLDV 362 LQIENE+YS+IRPKRV +G+RP+QAL ARG+QY+EVRC+DI+PF P+GI L +RFLD Sbjct: 299 LQIENEYYSNIRPKRVTYTGDRPIQALMARGIQYIEVRCLDINPFLPMGIDLPESRFLDA 358 Query: 363 FLHFLALESSCLTSDEEGAENRANFLATVKEGRRPGLQLHFKGATIGLKEWGEQLLDRMA 422 FL + AL S L ++ E +NFL+ VKEGRRPGL+L GA++ +K W +LL+++A Sbjct: 359 FLLYCALNDSPLFANNECGNATSNFLSVVKEGRRPGLELQRDGASVDMKAWATELLEKIA 418 Query: 423 PVADLLDRQRGGSQHRDSLQAQRAKLADPDSTPSARVLREIRASGNSFADYTLASSQRQA 482 P+A LLD+ G +H +L AQ AK+ DP TPSA+VL + SFA ++L SQ A Sbjct: 419 PLAALLDQSHGIGEHSQALDAQLAKVQDPSLTPSAQVLAAMAERKESFAQFSLHQSQLHA 478 Query: 483 AELMARPLPAATTADFVAIAQASLDAQRAIERTQEGDFDTFVAAYRASTLG 533 PL A A F +A+ASL Q +E+ + GDFD FV +Y+AS L Sbjct: 479 EHFRKEPLAAEEQARFEELARASLAQQAELEQNEVGDFDVFVGSYQASILA 529 >A4G406.1 A4G406_HERAR Glutamate--cysteine ligase EC=6.3.2.2 Length = 517 Score = 650 bits (1678), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/509 (63%), Positives = 378/509 (74%), Gaps = 3/509 (0%) Query: 23 HLALLGQGLRGIERETLRVDAQGHLARTPHPPALGSALTNELITTDYSEALLEFITPAMP 82 H +LL QG RGIERETLRVD QG LA PHP ALGSALTN ITTDYSE+LLEFITPA Sbjct: 6 HRSLLDQGRRGIERETLRVDMQGRLALDPHPAALGSALTNPHITTDYSESLLEFITPAEH 65 Query: 83 DIADALQRLDEIHRFAYAKLEGEFLWNASMPCVLPPEDEIPIAWYGNSHIGMLKHVYRRG 142 DIA L LD IHRF A+LE E LW+ SMPC+LP E +IPIAWYG SHIGM+KHVYRRG Sbjct: 66 DIATVLDELDRIHRFTNARLEHELLWSQSMPCILPDEADIPIAWYGTSHIGMIKHVYRRG 125 Query: 143 LALRYGRTMQCIAGIHYNFSLSEDLWEVLREGDDSVDLSLSRRDYQSERYIALIRNFRRY 202 LALRYG+ MQCIAG+HYN+SLSEDLW VL++ +S + + +QSE YIALIRNF RY Sbjct: 126 LALRYGKAMQCIAGLHYNYSLSEDLWRVLKKDANS---TADDKTFQSESYIALIRNFHRY 182 Query: 203 SWLLMYLFGASPAVATNFLRGRPHQLETLSEDTLYLPYGTSLRMSDLGYQNHAQANITPH 262 SWLLMYLFGASPA++ +FLRGR H+LETLS+DTLYLPY TSLRMSDLGYQN AQA + Sbjct: 183 SWLLMYLFGASPALSMHFLRGRQHELETLSDDTLYLPYATSLRMSDLGYQNDAQAGLMQP 242 Query: 263 YNNLPAYIRSLSHAVSEPYPPYEAIGTKRDGQWVQINTNILQIENEFYSSIRPKRVINSG 322 YN+L +Y+RSLS AV +PYP YEAIGT+RDG+W+Q+NTN+LQIENE+Y++IRPKRVINSG Sbjct: 243 YNDLESYMRSLSRAVRQPYPAYEAIGTRRDGEWIQLNTNLLQIENEYYATIRPKRVINSG 302 Query: 323 ERPVQALSARGVQYVEVRCMDIDPFNPLGIGLEAARFLDVFLHFLALESSCLTSDEEGAE 382 ERPV+AL ARGVQY+EVRCMDIDPF PLGI LE +RFLD FL F AL+ S T + E Sbjct: 303 ERPVEALCARGVQYIEVRCMDIDPFEPLGISLETSRFLDAFLLFCALDESPFTDEASHRE 362 Query: 383 NRANFLATVKEGRRPGLQLHFKGATIGLKEWGEQLLDRMAPVADLLDRQRGGSQHRDSLQ 442 NF TVK+GRRPGL L GA I L+ WG +LL+++ VA +LD H +L Sbjct: 363 KTENFARTVKQGRRPGLLLQRDGAPIALQAWGLELLEKIQAVAHVLDATSKDQPHTRALA 422 Query: 443 AQRAKLADPDSTPSARVLREIRASGNSFADYTLASSQRQAAELMARPLPAATTADFVAIA 502 Q+ KL P+ TPSARVL E++ + SF + + S A ARPL A F +A Sbjct: 423 TQKEKLLHPELTPSARVLAELQTTDQSFEQFGMRQSIAHAEYFRARPLSTEENAYFNTLA 482 Query: 503 QASLDAQRAIERTQEGDFDTFVAAYRAST 531 Q S+ AQ +ERTQ DFD FV AY T Sbjct: 483 QDSIAAQAEMERTQSDDFDAFVLAYSTRT 511 >F2KAR1.1 F2KAR1_PSEBR Glutamate--cysteine ligase Length = 532 Score = 649 bits (1675), Expect = 0.0, Method: Compositional matrix adjust. Identities = 317/531 (59%), Positives = 395/531 (74%), Gaps = 3/531 (0%) Query: 3 KDYRMTDLLNRRLQQLSQPQHLALLGQGLRGIERETLRVDAQGHLARTPHPPALGSALTN 62 K++ ++DLLNRRL L + +L+LL Q L GIERE LRV GHLA+TPHP ALGSALTN Sbjct: 2 KEFNLSDLLNRRLALLGERANLSLLEQCLHGIERECLRVTGDGHLAQTPHPKALGSALTN 61 Query: 63 ELITTDYSEALLEFITPAMPDIADALQRLDEIHRFAYAKLEGEFLWNASMPCVLPPEDEI 122 E ITTDYSE+LLEFITPA+ + AD L+ LD+IHRFAY+KL E+LW+ SMPC LP E++I Sbjct: 62 EQITTDYSESLLEFITPALANPADTLRSLDKIHRFAYSKLGDEYLWSPSMPCPLPAEEDI 121 Query: 123 PIAWYGNSHIGMLKHVYRRGLALRYGRTMQCIAGIHYNFSLSEDLWEVLREGDDSVDLSL 182 PIA+YG S+IG LK+VYR+GLALRYG+TMQCIAGIHYNFSL E LW +LR+ + + Sbjct: 122 PIAYYGTSNIGRLKYVYRKGLALRYGKTMQCIAGIHYNFSLPEKLWPLLRQAEG---VEA 178 Query: 183 SRRDYQSERYIALIRNFRRYSWLLMYLFGASPAVATNFLRGRPHQLETLSEDTLYLPYGT 242 S RD+QS YIALIRNFRRYSWLLMYLFGASPA+ FLRGRPHQLE L DTLYLPY T Sbjct: 179 SDRDFQSSAYIALIRNFRRYSWLLMYLFGASPALDAGFLRGRPHQLEQLDPDTLYLPYAT 238 Query: 243 SLRMSDLGYQNHAQANITPHYNNLPAYIRSLSHAVSEPYPPYEAIGTKRDGQWVQINTNI 302 SLRMSDLGYQ++AQA +TP YN+L +Y SL AV+ PY PY +GT ++G+WVQ+NTNI Sbjct: 239 SLRMSDLGYQSNAQAGLTPCYNDLASYTDSLRKAVATPYAPYVEVGTHQNGEWVQLNTNI 298 Query: 303 LQIENEFYSSIRPKRVINSGERPVQALSARGVQYVEVRCMDIDPFNPLGIGLEAARFLDV 362 LQIENE+YS+IRPKRV +GERP+QAL ARG+QYVEVRC+DI+PF P+GI L +RFLD Sbjct: 299 LQIENEYYSNIRPKRVTYTGERPIQALMARGIQYVEVRCLDINPFLPMGIDLTESRFLDA 358 Query: 363 FLHFLALESSCLTSDEEGAENRANFLATVKEGRRPGLQLHFKGATIGLKEWGEQLLDRMA 422 FL + L S + E +NFL VKEGR+PGLQL +G ++ ++ W +LL+++A Sbjct: 359 FLLYCGLNDSPQLENNECGNATSNFLTVVKEGRKPGLQLQRQGQSVDMQAWAVELLEKIA 418 Query: 423 PVADLLDRQRGGSQHRDSLQAQRAKLADPDSTPSARVLREIRASGNSFADYTLASSQRQA 482 P+A LLD+ +GG HR +L AQ AK+ DP TPSA+VL + SFA ++L S+ A Sbjct: 419 PLASLLDQSQGGDAHRQALDAQLAKVRDPSLTPSAQVLAAMAEHQESFAQFSLRQSKAHA 478 Query: 483 AELMARPLPAATTADFVAIAQASLDAQRAIERTQEGDFDTFVAAYRASTLG 533 A PLPA F A+ SL Q +E+ + GDFD FV +Y+AS L Sbjct: 479 EFFRAEPLPAQEQTAFEETARESLVQQTELEQNEVGDFDVFVGSYQASILA 529 >B0KHZ5.1 B0KHZ5_PSEPG Glutamate--cysteine ligase EC=6.3.2.2 Length = 530 Score = 648 bits (1672), Expect = 0.0, Method: Compositional matrix adjust. Identities = 324/531 (61%), Positives = 390/531 (73%), Gaps = 5/531 (0%) Query: 3 KDYRMTDLLNRRLQQLSQPQHLALLGQGLRGIERETLRVDAQGHLARTPHPPALGSALTN 62 K+Y ++DLLNRRL L +L LL Q L GIERE LRV +G LA+TPHP ALGSALTN Sbjct: 2 KEYILSDLLNRRLSLLGA--NLPLLKQCLHGIERECLRVTDEGRLAQTPHPDALGSALTN 59 Query: 63 ELITTDYSEALLEFITPAMPDIADALQRLDEIHRFAYAKLEGEFLWNASMPCVLPPEDEI 122 E ITTDYSE+LLEFITPA+PD A L+ L+E HRF Y+KL E+LW+ SMPC LP E++I Sbjct: 60 EQITTDYSESLLEFITPALPDPAKVLESLEETHRFVYSKLGDEYLWSPSMPCTLPAEEDI 119 Query: 123 PIAWYGNSHIGMLKHVYRRGLALRYGRTMQCIAGIHYNFSLSEDLWEVLREGDDSVDLSL 182 PIA YG S+IG LKHVYR+GLALRYGRTMQCIAGIHYNFSL E LW +LRE + S + Sbjct: 120 PIAEYGTSNIGKLKHVYRKGLALRYGRTMQCIAGIHYNFSLPEALWPLLREAEGSTE--- 176 Query: 183 SRRDYQSERYIALIRNFRRYSWLLMYLFGASPAVATNFLRGRPHQLETLSEDTLYLPYGT 242 RDYQS YIALIRNFRRYSWLLMYLFGASPA+ FLRGRPHQLE L +TL+LPY T Sbjct: 177 DDRDYQSSAYIALIRNFRRYSWLLMYLFGASPALDKGFLRGRPHQLEELDAETLFLPYAT 236 Query: 243 SLRMSDLGYQNHAQANITPHYNNLPAYIRSLSHAVSEPYPPYEAIGTKRDGQWVQINTNI 302 SLRMSDLGYQ++AQA +TP YNNL +Y SL AV PYPPY +GT DG+WVQ+NTNI Sbjct: 237 SLRMSDLGYQSNAQAGLTPCYNNLASYTDSLRKAVGTPYPPYVEVGTHVDGEWVQLNTNI 296 Query: 303 LQIENEFYSSIRPKRVINSGERPVQALSARGVQYVEVRCMDIDPFNPLGIGLEAARFLDV 362 LQIENE+YS+IRPKRV +GERP+QAL++RGVQYVEVRC+DI+PF P+GI L ARFLD Sbjct: 297 LQIENEYYSNIRPKRVTYTGERPIQALTSRGVQYVEVRCLDINPFLPVGIDLTEARFLDA 356 Query: 363 FLHFLALESSCLTSDEEGAENRANFLATVKEGRRPGLQLHFKGATIGLKEWGEQLLDRMA 422 FL F ALE S + E + NFL VKEGRRPGL+LH G IGLK+W +L++R+ Sbjct: 357 FLLFCALEESPQLDNGECGQCTDNFLTVVKEGRRPGLELHRDGQPIGLKDWASELIERIR 416 Query: 423 PVADLLDRQRGGSQHRDSLQAQRAKLADPDSTPSARVLREIRASGNSFADYTLASSQRQA 482 +ADLLD+ +GG H +L AQ+AK+ D TPSA+VL + SF ++L S+ A Sbjct: 417 QLADLLDQAQGGEAHAKALDAQQAKVDDTSLTPSAQVLARMTEHDESFVQFSLRQSRIHA 476 Query: 483 AELMARPLPAATTADFVAIAQASLDAQRAIERTQEGDFDTFVAAYRASTLG 533 +PL + F +A+ SL Q +E+ + GDFD FV AY+AS L Sbjct: 477 ETFREQPLSSEKQQAFETLARESLARQSELEQDEVGDFDLFVGAYQASILA 527 >A6VDX9.1 GSH1_PSEA7 Glutamate--cysteine ligase EC=6.3.2.2 Length = 527 Score = 644 bits (1662), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/530 (64%), Positives = 399/530 (75%), Gaps = 4/530 (0%) Query: 7 MTDLLNRRLQQLSQPQHLALLGQGLRGIERETLRVDAQGHLARTPHPPALGSALTNELIT 66 M+DLL+RRL L +L LL + L GIERE LRVD+ G LA TPHP ALGS LT+ IT Sbjct: 1 MSDLLSRRLALLGAAANLPLLTECLHGIERECLRVDSDGKLALTPHPRALGSTLTHPQIT 60 Query: 67 TDYSEALLEFITPAMPDIADALQRLDEIHRFAYAKLEGEFLWNASMPCVLPPEDEIPIAW 126 TDYSEALLEFITP D+AD L L+ IHRFA ++L+GE+LW+ SMPC LP E+ IPIA Sbjct: 61 TDYSEALLEFITPTETDVADTLGDLERIHRFASSQLDGEYLWSPSMPCELPDEESIPIAR 120 Query: 127 YGNSHIGMLKHVYRRGLALRYGRTMQCIAGIHYNFSLSEDLWEVLREGDDSVDLSLSRRD 186 YGNS IG LK+VYR+GLALRYG+TMQCIAGIHYNFSL E LW +LR+ + S L+ RD Sbjct: 121 YGNSMIGRLKYVYRKGLALRYGKTMQCIAGIHYNFSLPEKLWPLLRQAEGS---ELAERD 177 Query: 187 YQSERYIALIRNFRRYSWLLMYLFGASPAVATNFLRGRPHQLETLSEDTLYLPYGTSLRM 246 YQS YIALIRNFRRYSWLLMYLFGASPA+ FLRGRP QLE E TLYLPY TSLRM Sbjct: 178 YQSAAYIALIRNFRRYSWLLMYLFGASPALDAGFLRGRPSQLERFDEHTLYLPYATSLRM 237 Query: 247 SDLGYQNHAQANITPHYNNLPAYIRSLSHAVSEPYPPYEAIGTKRDGQWVQINTNILQIE 306 SDLGYQN+AQA +TP YN+L +YI SL AVS PYP YE IGTK+DG+WVQ+NTN+LQIE Sbjct: 238 SDLGYQNNAQAGLTPCYNDLQSYIDSLRKAVSTPYPAYEKIGTKQDGEWVQLNTNVLQIE 297 Query: 307 NEFYSSIRPKRVINSGERPVQALSARGVQYVEVRCMDIDPFNPLGIGLEAARFLDVFLHF 366 NE+YSSIRPKRV +GERPVQAL+ARGVQYVEVRC+DI+PF PLGI L+ ARFLD FL F Sbjct: 298 NEYYSSIRPKRVTYTGERPVQALAARGVQYVEVRCLDINPFLPLGIDLDEARFLDAFLLF 357 Query: 367 LALESSCLTSDEEGAENRANFLATVKEGRRPGLQLHFKGATIGLKEWGEQLLDRMAPVAD 426 A S L + E ++ NFLA VKEGRRPGLQL +G + LK+W +LL+R+A A Sbjct: 358 CAFSDSPLLNG-ECSDATDNFLAVVKEGRRPGLQLRRRGQPVELKDWASELLERIADTAA 416 Query: 427 LLDRQRGGSQHRDSLQAQRAKLADPDSTPSARVLREIRASGNSFADYTLASSQRQAAELM 486 LLDR RGG H +L AQRAK+ADP+ TPSA+VL+ +R G SF ++L S+ A Sbjct: 417 LLDRARGGEAHAAALAAQRAKVADPELTPSAQVLKVMRERGESFEAFSLRQSREHAEYFR 476 Query: 487 ARPLPAATTADFVAIAQASLDAQRAIERTQEGDFDTFVAAYRASTLGNIA 536 PL A A F +A ASL Q +ER Q+GDFDTFVAAY+AS LG I+ Sbjct: 477 QHPLAADEQARFEQMASASLAEQAELERDQDGDFDTFVAAYQASILGLIS 526