BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0079.p (118 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IPC8.1 D8IPC8_HERSS Putative pterin-4-alpha-carbinolamine dehy... 237 5e-61 A6SW93.1 A6SW93_JANMA Pterin-4-alpha-carbinolamine dehydratase E... 147 5e-34 F1W477.1 F1W477_9BURK Pterin-4-alpha-carbinolamine dehydratase 143 7e-33 A4G3H4.1 A4G3H4_HERAR Putative pterin-4-alpha-carbinolamine dehy... 138 2e-31 D6CPF4.1 D6CPF4_THIS3 Putative pterin-4-alpha-carbinolamine dehy... 131 3e-29 D5WYZ3.1 D5WYZ3_THIK1 Putative pterin-4-alpha-carbinolamine dehy... 131 3e-29 P61732.1 PHS_BDEBA Putative pterin-4-alpha-carbinolamine dehydra... 127 6e-28 E6PL06.1 E6PL06_9ZZZZ Putative pterin-4-alpha-carbinolamine dehy... 120 9e-26 B9YZP9.1 B9YZP9_9NEIS Putative pterin-4-alpha-carbinolamine dehy... 118 2e-25 E6QC14.1 E6QC14_9ZZZZ Putative pterin-4-alpha-carbinolamine dehy... 114 6e-24 >D8IPC8.1 D8IPC8_HERSS Putative pterin-4-alpha-carbinolamine dehydratase EC=4.2.1.96 Length = 118 Score = 237 bits (604), Expect = 5e-61, Method: Compositional matrix adjust. Identities = 114/118 (96%), Positives = 115/118 (97%) Query: 1 MSITASTLAAAHCIQPIDALDDSAIAAHLIALPDWQIEAGKLVRSFAFNNYYETLAFVNA 60 MSITASTLAAAHCIQP+DALDDSAI AHL LPDWQIEAGKLVRSFAFNNYYETLAFVNA Sbjct: 1 MSITASTLAAAHCIQPVDALDDSAITAHLAVLPDWQIEAGKLVRSFAFNNYYETLAFVNA 60 Query: 61 IAWMIHAEDHHPELIVSYNRCTVKFDTHSVNAGRGGLSANDFVCAAKVDALFAQRAHA 118 IAWMIHAEDHHPELIVSYNRCTVKFDTHSVNAGRGGLSANDFVCAAKVDALFAQRAHA Sbjct: 61 IAWMIHAEDHHPELIVSYNRCTVKFDTHSVNAGRGGLSANDFVCAAKVDALFAQRAHA 118 >A6SW93.1 A6SW93_JANMA Pterin-4-alpha-carbinolamine dehydratase EC=4.2.1.96 Length = 120 Score = 147 bits (371), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 64/111 (57%), Positives = 86/111 (77%) Query: 4 TASTLAAAHCIQPIDALDDSAIAAHLIALPDWQIEAGKLVRSFAFNNYYETLAFVNAIAW 63 +A+ L C + A +AA L ALP+W+++ GK+VR ++F NYY TLAFVNAIA+ Sbjct: 3 SAAELRLQRCQPQVLASSADEVAAGLQALPEWKLQDGKIVREYSFQNYYLTLAFVNAIAY 62 Query: 64 MIHAEDHHPELIVSYNRCTVKFDTHSVNAGRGGLSANDFVCAAKVDALFAQ 114 IH EDHHPEL+++Y +C VK+DTHSVNAG+GGLS NDF+CAAK+DA++AQ Sbjct: 63 TIHTEDHHPELVITYKQCLVKYDTHSVNAGKGGLSQNDFICAAKLDAIYAQ 113 >F1W477.1 F1W477_9BURK Pterin-4-alpha-carbinolamine dehydratase Length = 115 Score = 143 bits (361), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 63/112 (56%), Positives = 83/112 (74%) Query: 3 ITASTLAAAHCIQPIDALDDSAIAAHLIALPDWQIEAGKLVRSFAFNNYYETLAFVNAIA 62 +T + L C+ + AL + + L + W + GK+VRSF NYY+TL+F+NAIA Sbjct: 1 MTLTDLLEKKCVPGVSALPPAEVDTLLALIDSWHLADGKIVRSFDCKNYYDTLSFINAIA 60 Query: 63 WMIHAEDHHPELIVSYNRCTVKFDTHSVNAGRGGLSANDFVCAAKVDALFAQ 114 ++IHAEDHHPEL+V+YNRC VKFDTH+VN GRGGLS NDF+CAAK+DA+F Q Sbjct: 61 YVIHAEDHHPELVVTYNRCVVKFDTHTVNDGRGGLSVNDFICAAKIDAIFQQ 112 >A4G3H4.1 A4G3H4_HERAR Putative pterin-4-alpha-carbinolamine dehydratase (PHS) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Pterin carbinolamine dehydratase) (PCD) (4a-hydroxytetrahydrobiopterin dehydratase) EC=4.2.1.96 Length = 117 Score = 138 bits (348), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 60/115 (52%), Positives = 82/115 (71%) Query: 4 TASTLAAAHCIQPIDALDDSAIAAHLIALPDWQIEAGKLVRSFAFNNYYETLAFVNAIAW 63 A+ L C P AL+ IA L A+ W+++ GK+ R + F NYY T+AFVNAI + Sbjct: 3 NAADLRQQKCQPPTKALNAEEIAQRLQAVAAWRLQDGKIFREYTFKNYYATMAFVNAIVY 62 Query: 64 MIHAEDHHPELIVSYNRCTVKFDTHSVNAGRGGLSANDFVCAAKVDALFAQRAHA 118 +IHAEDHHPEL+++Y CTV+++THSVN G+GGLS NDF+CAAK+DA+F H+ Sbjct: 63 VIHAEDHHPELVITYKHCTVRYNTHSVNEGKGGLSDNDFICAAKLDAIFEYGMHS 117 >D6CPF4.1 D6CPF4_THIS3 Putative pterin-4-alpha-carbinolamine dehydratase EC=4.2.1.96 Length = 114 Score = 131 bits (329), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 62/117 (52%), Positives = 85/117 (72%), Gaps = 8/117 (6%) Query: 3 ITASTLAAAHCIQPIDA---LDDSAIAAHLIALPDWQIEAGKLVRSFAFNNYYETLAFVN 59 +T L +HC+ P+DA LD +A+ +L L WQ E G + +++AF NYY+TLAFVN Sbjct: 1 MTLQDLLDSHCM-PLDASQRLDTAAMTPYLQLLDGWQFEDGSIRKTYAFGNYYQTLAFVN 59 Query: 60 AIAWMIHAEDHHPELIVSYNRCTVKFDTHSVNAGRGGLSANDFVCAAKVDALFAQRA 116 A+AW++H EDHHP+L+V YNRC+V F+THS GG++ NDF+CAAK DA+FAQ A Sbjct: 60 ALAWVVHREDHHPDLLVQYNRCSVAFNTHSA----GGITRNDFICAAKADAMFAQGA 112 >D5WYZ3.1 D5WYZ3_THIK1 Putative pterin-4-alpha-carbinolamine dehydratase EC=4.2.1.96 Length = 114 Score = 131 bits (329), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 62/117 (52%), Positives = 85/117 (72%), Gaps = 8/117 (6%) Query: 3 ITASTLAAAHCIQPIDA---LDDSAIAAHLIALPDWQIEAGKLVRSFAFNNYYETLAFVN 59 +T L +HC+ P+DA LD +A+ +L L WQ E G + +++AF NYY+TLAFVN Sbjct: 1 MTLQDLLDSHCM-PLDASQRLDTAAMTPYLQLLDGWQFEDGSIRKTYAFGNYYQTLAFVN 59 Query: 60 AIAWMIHAEDHHPELIVSYNRCTVKFDTHSVNAGRGGLSANDFVCAAKVDALFAQRA 116 A+AW++H EDHHP+L+V YNRC+V F+THS GG++ NDF+CAAK DA+FAQ A Sbjct: 60 ALAWVVHREDHHPDLLVQYNRCSVAFNTHSA----GGITRNDFICAAKADAMFAQGA 112 >P61732.1 PHS_BDEBA Putative pterin-4-alpha-carbinolamine dehydratase EC=4.2.1.96 Length = 120 Score = 127 bits (319), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 60/107 (56%), Positives = 75/107 (70%), Gaps = 5/107 (4%) Query: 16 PID-ALDDSAIAAHLIALPDWQIEAGKLVRSFAFNNYYETLAFVNAIAWMIHAEDHHPEL 74 P+D AL I +L L W ++ + +SF F NYY+T+AFVNAIA+++H EDHHPEL Sbjct: 14 PVDQALTPEEIQQYLTVLDGWSLQGLHIAKSFEFKNYYQTIAFVNAIAFIVHTEDHHPEL 73 Query: 75 IVSYNRCTVKFDTHSVNAGRGGLSANDFVCAAKVDAL----FAQRAH 117 V YNRC VKF THSVN G GG+S NDF+CAAK+DAL FA +H Sbjct: 74 EVGYNRCVVKFYTHSVNEGLGGISENDFICAAKIDALAGNQFAPMSH 120 >E6PL06.1 E6PL06_9ZZZZ Putative pterin-4-alpha-carbinolamine dehydratase (PHS) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Pterin carbinolamine dehydratase) (PCD) EC=4.2.1.96 Length = 114 Score = 120 bits (300), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 60/118 (50%), Positives = 80/118 (67%), Gaps = 13/118 (11%) Query: 3 ITASTLAAAHCIQPIDALDDSAIAA-----HLIALPDWQIEAGKLVRSFAFNNYYETLAF 57 +T L HC AL+ +AA L LP+W+ + G + RS+AF +Y++T+AF Sbjct: 2 MTLDQLLQDHC----QALEGRPLAAAEVLKQLGVLPEWRHKDGSIQRSYAFRDYFDTIAF 57 Query: 58 VNAIAWMIHAEDHHPELIVSYNRCTVKFDTHSVNAGRGGLSANDFVCAAKVDALFAQR 115 VNA+AW++H EDHHP+L V YNRC V F+THSV GG+S NDF+CAAK DAL+AQR Sbjct: 58 VNALAWIVHREDHHPDLSVHYNRCVVAFNTHSV----GGISRNDFICAAKADALYAQR 111 >B9YZP9.1 B9YZP9_9NEIS Putative pterin-4-alpha-carbinolamine dehydratase EC=4.2.1.96 Length = 109 Score = 118 bits (296), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 59/116 (50%), Positives = 75/116 (64%), Gaps = 7/116 (6%) Query: 1 MSITASTLAAAHCIQPIDALDDSAIAAHLIALPDWQIEAGKLVRSFAFNNYYETLAFVNA 60 M++TA A H P+DA HL ALP W+I+ +LV++F F NYYET+AFVNA Sbjct: 1 MNLTAMHCQAQHGKSPLDATRQQQ---HLSALPGWEIQGIELVKTFRFGNYYETMAFVNA 57 Query: 61 IAWMIHAEDHHPELIVSYNRCTVKFDTHSVNAGRGGLSANDFVCAAKVDALFAQRA 116 +AW+ H EDHHP+L V YNR V F TH N GL+ NDF+CAAK +AL + A Sbjct: 58 LAWIAHQEDHHPDLSVHYNRAVVHFSTHDAN----GLTLNDFICAAKTEALLNRPA 109 >E6QC14.1 E6QC14_9ZZZZ Putative pterin-4-alpha-carbinolamine dehydratase (PHS) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Pterin carbinolamine dehydratase) (PCD) EC=4.2.1.96 Length = 109 Score = 114 bits (284), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 53/108 (49%), Positives = 70/108 (64%), Gaps = 7/108 (6%) Query: 8 LAAAHCIQ---PIDALDDSAIAAHLIALPDWQIEAGKLVRSFAFNNYYETLAFVNAIAWM 64 L AHC+ + LD + L +LP WQ+ + R F F N+YET+AFVNA+AW+ Sbjct: 5 LQHAHCVPCEGGVAPLDAEQVGLLLRSLPQWQVAGQAIRREFRFKNFYETMAFVNAVAWI 64 Query: 65 IHAEDHHPELIVSYNRCTVKFDTHSVNAGRGGLSANDFVCAAKVDALF 112 H EDHHP+L + YNRC V + TH++ GGLS NDF+CAA+VDAL Sbjct: 65 SHREDHHPDLELGYNRCVVHYSTHAI----GGLSENDFICAARVDALL 108