BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0028.p (259 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IP80.1 D8IP80_HERSS 7,8-dihydropteroate synthase protein EC=2.... 523 e-147 A4G4B2.1 A4G4B2_HERAR Dihydropteroate synthase (DHPS) (Dihydropt... 361 5e-98 F1W1H8.1 F1W1H8_9BURK Dihydropteroate synthase 352 3e-95 A6T079.1 A6T079_JANMA Dihydropteroate synthase EC=2.5.1.15 350 1e-94 C3X1P1.1 C3X1P1_OXAFO Dihydropteroate synthase 340 1e-91 C3XAA8.1 C3XAA8_OXAFO Dihydropteroate synthase 333 2e-89 E8YKK0.1 E8YKK0_9BURK Dihydropteroate synthase EC=2.5.1.15 318 5e-85 C6BJ80.1 C6BJ80_RALP1 Dihydropteroate synthase EC=2.5.1.15 316 2e-84 E1T525.1 E1T525_BURSG Dihydropteroate synthase EC=2.5.1.15 315 4e-84 B2UGP8.1 B2UGP8_RALPJ Dihydropteroate synthase EC=2.5.1.15 315 5e-84 >D8IP80.1 D8IP80_HERSS 7,8-dihydropteroate synthase protein EC=2.5.1.15 Length = 282 Score = 523 bits (1348), Expect = e-147, Method: Compositional matrix adjust. Identities = 258/259 (99%), Positives = 259/259 (100%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER Sbjct: 24 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 83 Query: 61 VLPVIYALRDCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLCV 120 VLPVIYALRDCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLCV Sbjct: 84 VLPVIYALRDCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLCV 143 Query: 121 MHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEHNL 180 MHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEHNL Sbjct: 144 MHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEHNL 203 Query: 181 ALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMIIRVH 240 ALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMIIRVH Sbjct: 204 ALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMIIRVH 263 Query: 241 DVAETVDALTLWQAGREDA 259 DVAETVDALT+WQAGREDA Sbjct: 264 DVAETVDALTMWQAGREDA 282 >A4G4B2.1 A4G4B2_HERAR Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase) EC=2.5.1.15 Length = 279 Score = 361 bits (927), Expect = 5e-98, Method: Compositional matrix adjust. Identities = 168/254 (66%), Positives = 207/254 (81%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILNVTPDSFSD G++ LD A++HAE+MIA GVDIIDIGGESTRPG +SL++EL+R Sbjct: 23 MGILNVTPDSFSDAGKYHALDAAISHAEEMIAAGVDIIDIGGESTRPGSQTVSLQDELDR 82 Query: 61 VLPVIYALRDCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLCV 120 V+P++YALRDCGKPLS+DTYKP VMR+ + A VDM+ND+NGFRA GA+EAV D++ LC+ Sbjct: 83 VMPLVYALRDCGKPLSIDTYKPEVMRQTIAAGVDMVNDVNGFRAPGALEAVADADCALCI 142 Query: 121 MHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEHNL 180 MHMQ PQ+MQ P+Y +VV +V AFL ++ + Q IARER+CIDPGFGFGK++ HN+ Sbjct: 143 MHMQKDPQSMQLKPEYENVVADVTAFLHERIAAIAQMNIARERLCIDPGFGFGKSLAHNI 202 Query: 181 ALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMIIRVH 240 ALLKN +L L LPLLAG+SRKSMIGA+ KP+ERRMAGS+ AL QGA I+RVH Sbjct: 203 ALLKNIGQLQAALDLPLLAGLSRKSMIGALLDKPVERRMAGSLAGALACVAQGARIVRVH 262 Query: 241 DVAETVDALTLWQA 254 DVAETVDALT+W A Sbjct: 263 DVAETVDALTVWHA 276 >F1W1H8.1 F1W1H8_9BURK Dihydropteroate synthase Length = 280 Score = 352 bits (903), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 167/257 (64%), Positives = 205/257 (79%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MG+LNVTPDSFSDGG+ Q LD ++ AEQMI +GVDIIDIGGES+RPG PL ++EEL R Sbjct: 24 MGVLNVTPDSFSDGGQFQSLDAVVSRAEQMIDEGVDIIDIGGESSRPGATPLPIDEELRR 83 Query: 61 VLPVIYALRDCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLCV 120 +LP+++ALRDCGKPLS+DTYKPAVM E L A DMINDI+GFR + AV++S+ GLC+ Sbjct: 84 ILPIVFALRDCGKPLSIDTYKPAVMVEVLAAGADMINDISGFRDMAGLTAVKESDCGLCI 143 Query: 121 MHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEHNL 180 MHM PQ MQ+ P Y DVV +V FL +V M GIARER+ IDPGFGFGKT+EHNL Sbjct: 144 MHMASDPQHMQRDPVYQDVVQQVSDFLSERVRQMEACGIARERLSIDPGFGFGKTLEHNL 203 Query: 181 ALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMIIRVH 240 ALLK+ R+L LGLPLLAGMSRKSMIG +TG+P+E+R+AGS+ AA+VA GA I+RVH Sbjct: 204 ALLKHIRQLATSLGLPLLAGMSRKSMIGNLTGRPVEQRLAGSLAAAIVATVNGAAILRVH 263 Query: 241 DVAETVDALTLWQAGRE 257 DVAET+DAL +W+A + Sbjct: 264 DVAETIDALKVWRAATQ 280 >A6T079.1 A6T079_JANMA Dihydropteroate synthase EC=2.5.1.15 Length = 278 Score = 350 bits (899), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 173/254 (68%), Positives = 208/254 (81%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILN+TPDSFSDGG++ LD AL+HAE+MIA GVDIIDIGGES+RPG +SL++EL+R Sbjct: 23 MGILNITPDSFSDGGKYHMLDTALSHAEEMIAAGVDIIDIGGESSRPGSLAVSLKDELDR 82 Query: 61 VLPVIYALRDCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLCV 120 V+P++YALRDCGKPLS+DTYKP VMRE + A DMINDINGFRA GA++AV DS+ LCV Sbjct: 83 VMPLVYALRDCGKPLSIDTYKPEVMRETIAAGADMINDINGFRAPGALQAVADSDCALCV 142 Query: 121 MHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEHNL 180 MHMQ PQ+MQ P+Y DVV EV FL+ ++ LM QAGIARERICIDPG GFGKT+ HN+ Sbjct: 143 MHMQNDPQSMQLQPEYDDVVAEVREFLRDRIGLMEQAGIARERICIDPGLGFGKTLAHNI 202 Query: 181 ALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMIIRVH 240 ALLKNT L L P+L G+SRK+MIGA+T +P+E+RMAGS+ AL A GA I+RVH Sbjct: 203 ALLKNTAELQAVLHSPILIGLSRKTMIGALTDRPVEQRMAGSLAGALAAVAHGARIVRVH 262 Query: 241 DVAETVDALTLWQA 254 DVAETVDAL +WQA Sbjct: 263 DVAETVDALRVWQA 276 >C3X1P1.1 C3X1P1_OXAFO Dihydropteroate synthase Length = 278 Score = 340 bits (872), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 162/256 (63%), Positives = 200/256 (78%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILNVTPDSFSDGG+ L ALT AE+MIA+GVDIIDIG ES+RPG P+SL+EEL+R Sbjct: 23 MGILNVTPDSFSDGGKFLSLSSALTRAEEMIAEGVDIIDIGAESSRPGSDPVSLQEELDR 82 Query: 61 VLPVIYALRDCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLCV 120 V+PV+ AL+DCGKPLS+DTYKP VM AL DMINDI+GFR+E ++EAV GLCV Sbjct: 83 VMPVVEALKDCGKPLSVDTYKPEVMSAALGESADMINDISGFRSEASLEAVIGHSCGLCV 142 Query: 121 MHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEHNL 180 MHMQG+P+TMQ P Y +V EV AFL +QV M AGI RIC+DPGFGFGKT+E NL Sbjct: 143 MHMQGEPKTMQDNPHYGNVTEEVVAFLHKQVLKMTNAGIGANRICVDPGFGFGKTLEDNL 202 Query: 181 ALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMIIRVH 240 LLKN + + L LP+LAG+SRKS++ A+TGKP+E+R+AG++ AL A ++GA I+RVH Sbjct: 203 VLLKNMSFIQKSLELPVLAGLSRKSVVAALTGKPVEKRLAGNLAIALAAVERGAAIVRVH 262 Query: 241 DVAETVDALTLWQAGR 256 +V ETVDAL +W A R Sbjct: 263 EVGETVDALKVWLATR 278 >C3XAA8.1 C3XAA8_OXAFO Dihydropteroate synthase Length = 278 Score = 333 bits (853), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 158/256 (61%), Positives = 201/256 (78%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILN+TPDSFSDGG++ L AL HAE MIADGVDIIDIG ES+RPG P+ L+EEL+R Sbjct: 23 MGILNITPDSFSDGGKYFSLSSALRHAEDMIADGVDIIDIGAESSRPGSEPVPLQEELDR 82 Query: 61 VLPVIYALRDCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLCV 120 V+PVI AL+DCGKPLS+DTYKP VM A+ A DMINDI GF++E +++AV D+ GLCV Sbjct: 83 VMPVIEALKDCGKPLSIDTYKPEVMAAAIAAGADMINDICGFQSEASLKAVLDNSCGLCV 142 Query: 121 MHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEHNL 180 MHMQG+P+TMQ P Y +V EV FL QV M + GIA+ERICIDPGFGFGK++E N+ Sbjct: 143 MHMQGKPKTMQDDPHYGNVTVEVTQFLSEQVKRMEKTGIAKERICIDPGFGFGKSLEDNI 202 Query: 181 ALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMIIRVH 240 LLK+ + +L LP+LAG+SRKS++ +TG+P+E+R+AG++ AL A + GA I+RVH Sbjct: 203 ILLKHIDFMQEKLDLPVLAGLSRKSVVAKLTGRPVEKRLAGNLAIALSAVEHGAAIVRVH 262 Query: 241 DVAETVDALTLWQAGR 256 +VAETVDAL +W A R Sbjct: 263 EVAETVDALKVWMATR 278 >E8YKK0.1 E8YKK0_9BURK Dihydropteroate synthase EC=2.5.1.15 Length = 299 Score = 318 bits (815), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 166/263 (63%), Positives = 199/263 (75%), Gaps = 4/263 (1%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILNVTPDSFSDGG+H AL HAE+M+ +G D+IDIGGESTRPG P+ L+EELER Sbjct: 30 MGILNVTPDSFSDGGQHAMRGDALRHAERMMLEGADMIDIGGESTRPGAPPVPLDEELER 89 Query: 61 VLPVIYALRDCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLCV 120 V+P+I L PLS+DTYKP VMR AL A D+INDI GFR GA+EAVR+S GLCV Sbjct: 90 VIPLIEQLHGTNVPLSVDTYKPEVMRRALSAGADLINDIWGFRMPGAVEAVRESNCGLCV 149 Query: 121 MHMQGQPQTMQQA-PQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGK-TVEH 178 MHM G+PQTMQ P Y +VVGEV FL+ +V ++RQAGIARERI +DPGFGFGK VEH Sbjct: 150 MHMLGEPQTMQLGEPAYGEVVGEVRQFLEERVAMLRQAGIARERISVDPGFGFGKAVVEH 209 Query: 179 NLALLKNTRRLIR--QLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMI 236 N ALL + P+LAGMSRKSMIGAVTG+P R+AGS+ AA++AA++GA I Sbjct: 210 NYALLARLADTAPRAEPPYPILAGMSRKSMIGAVTGRPAPERVAGSVAAAVLAAERGAAI 269 Query: 237 IRVHDVAETVDALTLWQAGREDA 259 +RVHDVA+TVDAL +W A R+ A Sbjct: 270 VRVHDVAQTVDALKVWAALRDAA 292 >C6BJ80.1 C6BJ80_RALP1 Dihydropteroate synthase EC=2.5.1.15 Length = 265 Score = 316 bits (809), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 162/259 (62%), Positives = 198/259 (76%), Gaps = 2/259 (0%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILNVTPDSFSDGG+H D AL HAEQ+IA+GVD+IDIGGES+RPG PLSL+ EL+R Sbjct: 1 MGILNVTPDSFSDGGQHATRDAALRHAEQLIAEGVDMIDIGGESSRPGAEPLSLQAELDR 60 Query: 61 VLPVIYALRDCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLCV 120 V+P++ ALR+CGKPLS+DTYKP VMR L A D+INDI GFR GAIE V AGLCV Sbjct: 61 VMPIVEALRECGKPLSIDTYKPEVMRATLDAGADLINDIWGFRRPGAIEVVAKGNAGLCV 120 Query: 121 MHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEHNL 180 MHMQ P+TMQ+AP Y D++GEVE FL+ Q + + AG+A ERI +DPGFGFGKT +HNL Sbjct: 121 MHMQRDPETMQEAPSYVDLMGEVEVFLRTQTEALMAAGVAAERISLDPGFGFGKTPDHNL 180 Query: 181 ALLKNTRRLIRQLGLPLLAGMSRKSMIGAVT-GKPLERRMAGSIGAALVAAQQGAMIIRV 239 +L R +GLPLLAG+SRKS +GAV GKP R+ S+ AAL+AA++GA I+RV Sbjct: 181 TMLNRLAEFQR-IGLPLLAGLSRKSTLGAVLGGKPPAERVTASVAAALLAAERGAFIVRV 239 Query: 240 HDVAETVDALTLWQAGRED 258 HDV TV+A+ LW A R + Sbjct: 240 HDVQPTVEAIQLWWAMRHE 258 >E1T525.1 E1T525_BURSG Dihydropteroate synthase EC=2.5.1.15 Length = 298 Score = 315 bits (807), Expect = 4e-84, Method: Compositional matrix adjust. Identities = 169/266 (63%), Positives = 198/266 (74%), Gaps = 10/266 (3%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILNVTPDSFSDGG++ AL AE+M+ +G DIIDIGGESTRPG P+ L+EELER Sbjct: 29 MGILNVTPDSFSDGGQYAMHGDALRQAERMMLEGADIIDIGGESTRPGAPPVPLDEELER 88 Query: 61 VLPVIYALRDCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLCV 120 V+P+I LR PLS+DTYKP VMR AL A D+INDI GFR GAI+AVRDS+ GLCV Sbjct: 89 VIPLIEQLRGANVPLSVDTYKPEVMRRALNAGADLINDIWGFRMPGAIDAVRDSDCGLCV 148 Query: 121 MHMQGQPQTMQQA-PQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGK-TVEH 178 MHM G+PQTMQ P Y DVV EV FL +V +RQAGIARERI +DPGFGFGK VEH Sbjct: 149 MHMLGEPQTMQLGEPAYGDVVSEVSEFLNERVTALRQAGIARERISVDPGFGFGKAVVEH 208 Query: 179 NLALLKNTRRLIRQL-----GLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQG 233 N ALL RL P+LAGMSRKSMIGAVTG+P R+AGS+ AA++AA++G Sbjct: 209 NYALLA---RLADSAPPADPPYPILAGMSRKSMIGAVTGRPAAERVAGSVAAAVLAAERG 265 Query: 234 AMIIRVHDVAETVDALTLWQAGREDA 259 A I+RVHDVA+TVDAL +W A R+ A Sbjct: 266 AAILRVHDVAQTVDALKVWAALRDAA 291 >B2UGP8.1 B2UGP8_RALPJ Dihydropteroate synthase EC=2.5.1.15 Length = 265 Score = 315 bits (806), Expect = 5e-84, Method: Compositional matrix adjust. Identities = 162/259 (62%), Positives = 198/259 (76%), Gaps = 2/259 (0%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILNVTPDSFSDGGRH D AL HAEQ+I +GVD+IDIGGES+RPG PLSL+ EL+R Sbjct: 1 MGILNVTPDSFSDGGRHATRDAALRHAEQLITEGVDMIDIGGESSRPGAEPLSLQAELDR 60 Query: 61 VLPVIYALRDCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLCV 120 V+P++ ALR+CGKPLS+DTYKP VMR L A D+INDI GFR GAIEAV AGLCV Sbjct: 61 VMPIVEALRECGKPLSIDTYKPEVMRATLDAGADLINDIWGFRRPGAIEAVAKGNAGLCV 120 Query: 121 MHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEHNL 180 MHMQ P+TMQ+AP Y D++GEVEAFL Q + + AG+A ER+ +DPGFGFGKT +HNL Sbjct: 121 MHMQRDPETMQEAPSYVDLMGEVEAFLCTQTEALMAAGVAAERVSLDPGFGFGKTPDHNL 180 Query: 181 ALLKNTRRLIRQLGLPLLAGMSRKSMIGAVT-GKPLERRMAGSIGAALVAAQQGAMIIRV 239 +L R +GLPLLAG+SRKS +GAV GKP R+ S+ AAL+AA++GA I+RV Sbjct: 181 TMLNRLAEFQR-IGLPLLAGLSRKSTLGAVLGGKPPAERVTVSVAAALLAAERGAFIVRV 239 Query: 240 HDVAETVDALTLWQAGRED 258 HDV T++A+ LW A R + Sbjct: 240 HDVQPTLEAIQLWWAMRHE 258