BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0006.0029.p (323 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IPM7.1 D8IPM7_HERSS Thymidylate synthase EC=2.1.1.45 672 0.0 A6SX86.1 A6SX86_JANMA Thymidylate synthase EC=2.1.1.45 551 e-155 A4G3Z8.1 A4G3Z8_HERAR Thymidylate synthase EC=2.1.1.45 546 e-153 D4XJC2.1 D4XJC2_9BURK Thymidylate synthase EC=2.1.1.45 529 e-148 B2JF48.1 B2JF48_BURP8 Thymidylate synthase EC=2.1.1.45 524 e-147 E3HF60.1 E3HF60_ACHXA Thymidylate synthase EC=2.1.1.45 523 e-146 B4EAM0.1 B4EAM0_BURCJ Thymidylate synthase EC=2.1.1.45 522 e-146 Q2SXY2.1 Q2SXY2_BURTA Thymidylate synthase EC=2.1.1.45 522 e-146 Q39IC0.1 Q39IC0_BURS3 Thymidylate synthase EC=2.1.1.45 522 e-146 F0GAT3.1 F0GAT3_9BURK Thymidylate synthase EC=2.1.1.45 521 e-146 >D8IPM7.1 D8IPM7_HERSS Thymidylate synthase EC=2.1.1.45 Length = 323 Score = 672 bits (1734), Expect = 0.0, Method: Compositional matrix adjust. Identities = 322/323 (99%), Positives = 323/323 (100%) Query: 1 MKQYQDLIQDVLENGSWQDNRTGIRTLSIPGAMMRFDLQKGFPAVTTKRLAFKSVVGELC 60 MKQYQDLIQDVLENGSWQDNRTGIRTLSIPGAMMRFDLQKGFPAVTTKRLAFKSVVGELC Sbjct: 1 MKQYQDLIQDVLENGSWQDNRTGIRTLSIPGAMMRFDLQKGFPAVTTKRLAFKSVVGELC 60 Query: 61 GFLRATRSAADFRALGCKVWDQNANENADWLANPFRSGADDLGPVYGVQWRQWPAYKLID 120 GFLRATRSAADFRALGCKVWDQNANENADWLANPFRSGADDLGPVYGVQWRQWPAYKLID Sbjct: 61 GFLRATRSAADFRALGCKVWDQNANENADWLANPFRSGADDLGPVYGVQWRQWPAYKLID 120 Query: 121 AAHTTQIEAARSKGFAIVSSLRDEGVEKVLLYKAVDQLRECLDTIVNNPGSRRILFHGWN 180 AAHTTQIEAARSKGFAIVSSL+DEGVEKVLLYKAVDQLRECLDTIVNNPGSRRILFHGWN Sbjct: 121 AAHTTQIEAARSKGFAIVSSLQDEGVEKVLLYKAVDQLRECLDTIVNNPGSRRILFHGWN 180 Query: 181 CAVLDEVALPACHLLYQFLPNQSTGEISLCLYVRSNDIGLGTPFNLAEGAALLHLVARLT 240 CAVLDEVALPACHLLYQFLPNQSTGEISLCLYVRSNDIGLGTPFNLAEGAALLHLVARLT Sbjct: 181 CAVLDEVALPACHLLYQFLPNQSTGEISLCLYVRSNDIGLGTPFNLAEGAALLHLVARLT 240 Query: 241 GYKPRWFSYFVGDAHIYENHIDMVKEQLTRAPYPLPQLEIADRVPEFARTGRYEPQWLEL 300 GYKPRWFSYFVGDAHIYENHIDMVKEQLTRAPYPLPQLEIADRVPEFARTGRYEPQWLEL Sbjct: 241 GYKPRWFSYFVGDAHIYENHIDMVKEQLTRAPYPLPQLEIADRVPEFARTGRYEPQWLEL 300 Query: 301 VEPSDFSLVNYQHHAPLTAPMAV 323 VEPSDFSLVNYQHHAPLTAPMAV Sbjct: 301 VEPSDFSLVNYQHHAPLTAPMAV 323 >A6SX86.1 A6SX86_JANMA Thymidylate synthase EC=2.1.1.45 Length = 324 Score = 551 bits (1419), Expect = e-155, Method: Compositional matrix adjust. Identities = 248/324 (76%), Positives = 291/324 (89%), Gaps = 1/324 (0%) Query: 1 MKQYQDLIQDVLENGSWQDNRTGIRTLSIPGAMMRFDLQK-GFPAVTTKRLAFKSVVGEL 59 MKQY DL++ VL+ G+WQ+NRTGIRT+SIPGAM+RFDLQK GFPA+TTKRLAFKSV+GEL Sbjct: 1 MKQYLDLVRTVLDTGTWQENRTGIRTISIPGAMLRFDLQKDGFPAITTKRLAFKSVIGEL 60 Query: 60 CGFLRATRSAADFRALGCKVWDQNANENADWLANPFRSGADDLGPVYGVQWRQWPAYKLI 119 GFLRATRSAA+FR LGCKVWDQNANEN +WL NP+R+G DDLGPVYGVQWRQWPAYKL+ Sbjct: 61 IGFLRATRSAAEFRELGCKVWDQNANENTEWLNNPYRTGPDDLGPVYGVQWRQWPAYKLL 120 Query: 120 DAAHTTQIEAARSKGFAIVSSLRDEGVEKVLLYKAVDQLRECLDTIVNNPGSRRILFHGW 179 DA QI+ A+ +GF +VS++ DEG +KVLLYKA+DQLR+CLDTI+ NPGSRRILFHGW Sbjct: 121 DADQQAQIDDAQKRGFRVVSTVNDEGKDKVLLYKAIDQLRDCLDTIIKNPGSRRILFHGW 180 Query: 180 NCAVLDEVALPACHLLYQFLPNQSTGEISLCLYVRSNDIGLGTPFNLAEGAALLHLVARL 239 NCA LD +ALPACHLLYQF+PN +T EISLCLY+RSNDIGLGTPFNLAE AALLH+V RL Sbjct: 181 NCADLDAIALPACHLLYQFIPNATTKEISLCLYIRSNDIGLGTPFNLAEAAALLHVVGRL 240 Query: 240 TGYKPRWFSYFVGDAHIYENHIDMVKEQLTRAPYPLPQLEIADRVPEFARTGRYEPQWLE 299 TGY P+WF+YF+GDAHIYENH+DM+ EQ+TRAP+P PQL ++DR+P+FA TG+YEP+WLE Sbjct: 241 TGYTPKWFTYFIGDAHIYENHLDMLNEQMTRAPHPAPQLVLSDRIPDFAVTGKYEPEWLE 300 Query: 300 LVEPSDFSLVNYQHHAPLTAPMAV 323 +EP DFSL NYQHHAPLTAPMAV Sbjct: 301 KLEPGDFSLENYQHHAPLTAPMAV 324 >A4G3Z8.1 A4G3Z8_HERAR Thymidylate synthase EC=2.1.1.45 Length = 324 Score = 546 bits (1407), Expect = e-153, Method: Compositional matrix adjust. Identities = 244/324 (75%), Positives = 293/324 (90%), Gaps = 1/324 (0%) Query: 1 MKQYQDLIQDVLENGSWQDNRTGIRTLSIPGAMMRFDLQK-GFPAVTTKRLAFKSVVGEL 59 MKQY DL++ VL++G+WQ+NRTGIRT+SIPGAM+RFDLQK GFPA+TTKRLAFKSV+GEL Sbjct: 1 MKQYLDLVRTVLDSGTWQENRTGIRTISIPGAMLRFDLQKDGFPAITTKRLAFKSVIGEL 60 Query: 60 CGFLRATRSAADFRALGCKVWDQNANENADWLANPFRSGADDLGPVYGVQWRQWPAYKLI 119 GFLRA+RSAA+FRALGCKVWDQNANENA+WL NP+R G DDLGPVYGVQWRQWPAYKL+ Sbjct: 61 IGFLRASRSAAEFRALGCKVWDQNANENAEWLNNPYRLGEDDLGPVYGVQWRQWPAYKLL 120 Query: 120 DAAHTTQIEAARSKGFAIVSSLRDEGVEKVLLYKAVDQLRECLDTIVNNPGSRRILFHGW 179 DA + QI+ A+ +GF ++S++ DEG++KVL+YKA+DQLR+CLDTI+NNP SRRILFHGW Sbjct: 121 DADNKLQIQDAQKRGFRLISAVNDEGIDKVLMYKAIDQLRDCLDTIINNPASRRILFHGW 180 Query: 180 NCAVLDEVALPACHLLYQFLPNQSTGEISLCLYVRSNDIGLGTPFNLAEGAALLHLVARL 239 NCA LD +ALPACHLLYQFLPNQ+T EISLCLY+RSNDIGLGTPFNLAE AALLH+V RL Sbjct: 181 NCAELDAIALPACHLLYQFLPNQTTKEISLCLYIRSNDIGLGTPFNLAEAAALLHVVGRL 240 Query: 240 TGYKPRWFSYFVGDAHIYENHIDMVKEQLTRAPYPLPQLEIADRVPEFARTGRYEPQWLE 299 TGY P+WF+YF+GDAHIYENH+DM+ EQ+TR PY P+L ++DR+P++ TG+YEP+WLE Sbjct: 241 TGYTPKWFTYFIGDAHIYENHLDMLNEQMTREPYAAPRLVLSDRIPDYRVTGKYEPEWLE 300 Query: 300 LVEPSDFSLVNYQHHAPLTAPMAV 323 +EP DFSL NYQHHAPL+APMAV Sbjct: 301 KLEPGDFSLENYQHHAPLSAPMAV 324 >D4XJC2.1 D4XJC2_9BURK Thymidylate synthase EC=2.1.1.45 Length = 323 Score = 529 bits (1362), Expect = e-148, Method: Compositional matrix adjust. Identities = 241/323 (74%), Positives = 281/323 (86%) Query: 1 MKQYQDLIQDVLENGSWQDNRTGIRTLSIPGAMMRFDLQKGFPAVTTKRLAFKSVVGELC 60 MKQY DL+Q +L+ GSWQ+NRTGIRT+S+PGA +RFDLQKGFPAVTTK+LAFKS +GE+ Sbjct: 1 MKQYLDLVQSILDTGSWQENRTGIRTISMPGASLRFDLQKGFPAVTTKKLAFKSAIGEMV 60 Query: 61 GFLRATRSAADFRALGCKVWDQNANENADWLANPFRSGADDLGPVYGVQWRQWPAYKLID 120 GFLRA+RSAA+FR LGCKVWDQNANEN+ WLANP+R G DDLGPVYGVQWRQWPAYKL+D Sbjct: 61 GFLRASRSAAEFRELGCKVWDQNANENSQWLANPYREGPDDLGPVYGVQWRQWPAYKLLD 120 Query: 121 AAHTTQIEAARSKGFAIVSSLRDEGVEKVLLYKAVDQLRECLDTIVNNPGSRRILFHGWN 180 A+ Q+E A S+G++ V+ L + GV KVLLYKAVDQLR+CLDTI PG RRILFHGWN Sbjct: 121 ASRPGQLEDALSRGYSKVADLEEGGVPKVLLYKAVDQLRQCLDTIHERPGDRRILFHGWN 180 Query: 181 CAVLDEVALPACHLLYQFLPNQSTGEISLCLYVRSNDIGLGTPFNLAEGAALLHLVARLT 240 A ++E+ALP CHLLYQFLPN +T EISLCLY+RSND+GLGTPFNL EGAALLHLV RLT Sbjct: 181 WAQIEEMALPPCHLLYQFLPNATTREISLCLYIRSNDVGLGTPFNLTEGAALLHLVGRLT 240 Query: 241 GYKPRWFSYFVGDAHIYENHIDMVKEQLTRAPYPLPQLEIADRVPEFARTGRYEPQWLEL 300 GY PRWF+YF+GDAHIYENH+ M++EQLTR PY P+L ++DR+P+FA TGRYEP+WLE Sbjct: 241 GYTPRWFTYFIGDAHIYENHLPMLREQLTREPYESPRLVLSDRIPDFAVTGRYEPEWLEK 300 Query: 301 VEPSDFSLVNYQHHAPLTAPMAV 323 VEPSDFSL Y HHAPLTAPMAV Sbjct: 301 VEPSDFSLSGYTHHAPLTAPMAV 323 >B2JF48.1 B2JF48_BURP8 Thymidylate synthase EC=2.1.1.45 Length = 323 Score = 524 bits (1350), Expect = e-147, Method: Compositional matrix adjust. Identities = 235/323 (72%), Positives = 281/323 (86%) Query: 1 MKQYQDLIQDVLENGSWQDNRTGIRTLSIPGAMMRFDLQKGFPAVTTKRLAFKSVVGELC 60 MKQY DL++ +L+ GSWQ+NRTGIRT+S+PGAM+RFDLQ+GFPAVTTK+LAFKS +GEL Sbjct: 1 MKQYLDLVRTILDTGSWQENRTGIRTISMPGAMLRFDLQQGFPAVTTKKLAFKSAIGELI 60 Query: 61 GFLRATRSAADFRALGCKVWDQNANENADWLANPFRSGADDLGPVYGVQWRQWPAYKLID 120 GFLRA+RSAADFRALGCKVWD NANENA WLANP+R G DDLG VYGVQWR+WPAYK++D Sbjct: 61 GFLRASRSAADFRALGCKVWDANANENAQWLANPYREGPDDLGDVYGVQWRRWPAYKVLD 120 Query: 121 AAHTTQIEAARSKGFAIVSSLRDEGVEKVLLYKAVDQLRECLDTIVNNPGSRRILFHGWN 180 A + Q+E A S+G+A V+ ++G+ KVLLYKA+DQLR+CLD I++NP RRILFH WN Sbjct: 121 ATASAQLEDAASRGYAPVTEFEEDGMRKVLLYKAIDQLRQCLDAIMHNPSDRRILFHAWN 180 Query: 181 CAVLDEVALPACHLLYQFLPNQSTGEISLCLYVRSNDIGLGTPFNLAEGAALLHLVARLT 240 AVL+E+ALPACHLLYQFLPN S EISLCLY+RSND+GLGTPFNL EGAALLHLV RLT Sbjct: 181 PAVLEEIALPACHLLYQFLPNASKREISLCLYIRSNDVGLGTPFNLTEGAALLHLVGRLT 240 Query: 241 GYKPRWFSYFVGDAHIYENHIDMVKEQLTRAPYPLPQLEIADRVPEFARTGRYEPQWLEL 300 GY PRWF+YF+GDAHIYEN +DM+++QLTR PY PQ I++RVP++ +TG YEP+WLE Sbjct: 241 GYTPRWFTYFIGDAHIYENQLDMLQQQLTRDPYESPQFAISERVPDYTKTGVYEPEWLEK 300 Query: 301 VEPSDFSLVNYQHHAPLTAPMAV 323 VEPSDFSLV Y+HH PLTAPMA+ Sbjct: 301 VEPSDFSLVGYRHHEPLTAPMAI 323 >E3HF60.1 E3HF60_ACHXA Thymidylate synthase EC=2.1.1.45 Length = 323 Score = 523 bits (1347), Expect = e-146, Method: Compositional matrix adjust. Identities = 239/323 (73%), Positives = 277/323 (85%) Query: 1 MKQYQDLIQDVLENGSWQDNRTGIRTLSIPGAMMRFDLQKGFPAVTTKRLAFKSVVGELC 60 MKQY DL+Q +L+ G+WQ+NRTGIRTLS+PGA +RFDLQKGFPAVTTK+LAFKS +GE+ Sbjct: 1 MKQYLDLVQSILDTGAWQENRTGIRTLSMPGASLRFDLQKGFPAVTTKKLAFKSAIGEMV 60 Query: 61 GFLRATRSAADFRALGCKVWDQNANENADWLANPFRSGADDLGPVYGVQWRQWPAYKLID 120 GFLRA+RSAA+FR LGCKVWDQNANEN+ WLANP+R G DDLGPVYGVQWRQWPAYK++D Sbjct: 61 GFLRASRSAAEFRELGCKVWDQNANENSQWLANPYREGPDDLGPVYGVQWRQWPAYKMLD 120 Query: 121 AAHTTQIEAARSKGFAIVSSLRDEGVEKVLLYKAVDQLRECLDTIVNNPGSRRILFHGWN 180 A+ QI A S+G+A V+ L + GV KVLLYKAVDQLR+CLDTI PG RRILFHGWN Sbjct: 121 ASRPAQIADALSRGYAQVAELEEGGVPKVLLYKAVDQLRQCLDTIHERPGDRRILFHGWN 180 Query: 181 CAVLDEVALPACHLLYQFLPNQSTGEISLCLYVRSNDIGLGTPFNLAEGAALLHLVARLT 240 A ++E+ALP CHLLYQFLPN +T EISLCLY+RSND+GLGTPFNL EGAALLHLV RLT Sbjct: 181 WAQIEEMALPPCHLLYQFLPNATTREISLCLYIRSNDVGLGTPFNLTEGAALLHLVGRLT 240 Query: 241 GYKPRWFSYFVGDAHIYENHIDMVKEQLTRAPYPLPQLEIADRVPEFARTGRYEPQWLEL 300 GY PRWF+YF+GDAHIYENH+ M++EQLTR PY P L ++DR+P+FA TGRYEP+WLE Sbjct: 241 GYTPRWFTYFIGDAHIYENHLPMLREQLTREPYEAPTLVLSDRIPDFAVTGRYEPEWLEK 300 Query: 301 VEPSDFSLVNYQHHAPLTAPMAV 323 VEP DFSL Y HHAPLTA MAV Sbjct: 301 VEPGDFSLSGYTHHAPLTAAMAV 323 >B4EAM0.1 B4EAM0_BURCJ Thymidylate synthase EC=2.1.1.45 Length = 323 Score = 522 bits (1344), Expect = e-146, Method: Compositional matrix adjust. Identities = 237/323 (73%), Positives = 277/323 (85%) Query: 1 MKQYQDLIQDVLENGSWQDNRTGIRTLSIPGAMMRFDLQKGFPAVTTKRLAFKSVVGELC 60 MKQY DL++ +L+ GSWQ+NRTGIRT+S+PGAM+RFDLQ+GFPAVTTK+LAFKS +GEL Sbjct: 1 MKQYLDLVRTILDTGSWQENRTGIRTISMPGAMLRFDLQQGFPAVTTKKLAFKSAIGELV 60 Query: 61 GFLRATRSAADFRALGCKVWDQNANENADWLANPFRSGADDLGPVYGVQWRQWPAYKLID 120 GFLRA+RSAADFRALGCKVWD NANENA WLANP+R G DDLG VYGVQWRQWP YK++D Sbjct: 61 GFLRASRSAADFRALGCKVWDANANENAQWLANPYRQGVDDLGDVYGVQWRQWPGYKVLD 120 Query: 121 AAHTTQIEAARSKGFAIVSSLRDEGVEKVLLYKAVDQLRECLDTIVNNPGSRRILFHGWN 180 A QI A +GF IV+ ++G KVLLYKA+DQLR+CLDTI+ NP RRILFH WN Sbjct: 121 AGADAQIADATRRGFRIVTRFDEDGAPKVLLYKAIDQLRQCLDTIMENPSDRRILFHAWN 180 Query: 181 CAVLDEVALPACHLLYQFLPNQSTGEISLCLYVRSNDIGLGTPFNLAEGAALLHLVARLT 240 AVLD++ALPACHLLYQFLPN + EISLCLY+RSND+GLGTPFNL EGAALL LV RLT Sbjct: 181 PAVLDQIALPACHLLYQFLPNATKREISLCLYIRSNDVGLGTPFNLTEGAALLSLVGRLT 240 Query: 241 GYKPRWFSYFVGDAHIYENHIDMVKEQLTRAPYPLPQLEIADRVPEFARTGRYEPQWLEL 300 GY PRWF+YF+GDAHIYEN +DM+++QLTR PY P+LEIA+RVP++A+TG Y P+WLE Sbjct: 241 GYTPRWFTYFIGDAHIYENQLDMLQQQLTREPYESPRLEIAERVPDYAKTGVYAPEWLEQ 300 Query: 301 VEPSDFSLVNYQHHAPLTAPMAV 323 VEPSDFSLV Y+HH PLTAPMAV Sbjct: 301 VEPSDFSLVGYRHHEPLTAPMAV 323 >Q2SXY2.1 Q2SXY2_BURTA Thymidylate synthase EC=2.1.1.45 Length = 323 Score = 522 bits (1344), Expect = e-146, Method: Compositional matrix adjust. Identities = 238/323 (73%), Positives = 280/323 (86%) Query: 1 MKQYQDLIQDVLENGSWQDNRTGIRTLSIPGAMMRFDLQKGFPAVTTKRLAFKSVVGELC 60 MKQY DL++ +L+ G+WQ NRTGIRT+ IPGAM+RFDLQ+GFPAVTTK+LAFKS +GEL Sbjct: 1 MKQYLDLVRTILDTGTWQSNRTGIRTIGIPGAMLRFDLQQGFPAVTTKKLAFKSAIGELV 60 Query: 61 GFLRATRSAADFRALGCKVWDQNANENADWLANPFRSGADDLGPVYGVQWRQWPAYKLID 120 GFLRATRSAA+FRALGCKVWD NANENA WLANP+R GADDLG VYGVQWR+WP YK++D Sbjct: 61 GFLRATRSAAEFRALGCKVWDANANENAQWLANPYRRGADDLGDVYGVQWRRWPGYKVLD 120 Query: 121 AAHTTQIEAARSKGFAIVSSLRDEGVEKVLLYKAVDQLRECLDTIVNNPGSRRILFHGWN 180 A QI A S+GF IV+ + G +KVLL+KA+DQLR+CLDTIV +P SRRILFHGWN Sbjct: 121 AHADAQIADATSRGFRIVARFEEGGADKVLLHKAIDQLRDCLDTIVRDPSSRRILFHGWN 180 Query: 181 CAVLDEVALPACHLLYQFLPNQSTGEISLCLYVRSNDIGLGTPFNLAEGAALLHLVARLT 240 AVLDE+ALPACHLLYQFLPN EISLCLY+RSND+GLGTPFNLAEGAALL LV RLT Sbjct: 181 PAVLDEIALPACHLLYQFLPNVERREISLCLYIRSNDVGLGTPFNLAEGAALLTLVGRLT 240 Query: 241 GYKPRWFSYFVGDAHIYENHIDMVKEQLTRAPYPLPQLEIADRVPEFARTGRYEPQWLEL 300 GY PRWF+YF+GDAHIYEN +DM+K+QL R P+ P+LE+A+RVP++A+TG+YEPQWLE Sbjct: 241 GYSPRWFTYFIGDAHIYENQLDMLKQQLEREPFESPRLELAERVPDYAKTGKYEPQWLER 300 Query: 301 VEPSDFSLVNYQHHAPLTAPMAV 323 VEPSDF+LV Y+HH PL+APMAV Sbjct: 301 VEPSDFTLVGYRHHEPLSAPMAV 323 >Q39IC0.1 Q39IC0_BURS3 Thymidylate synthase EC=2.1.1.45 Length = 323 Score = 522 bits (1344), Expect = e-146, Method: Compositional matrix adjust. Identities = 236/323 (73%), Positives = 277/323 (85%) Query: 1 MKQYQDLIQDVLENGSWQDNRTGIRTLSIPGAMMRFDLQKGFPAVTTKRLAFKSVVGELC 60 MKQY DL++ +L+ G+WQ+NRTGIRT+S+PGAM+RFDLQ+GFPAVTTK+LAFKS +GEL Sbjct: 1 MKQYLDLVRTILDTGTWQENRTGIRTISMPGAMLRFDLQQGFPAVTTKKLAFKSAIGELV 60 Query: 61 GFLRATRSAADFRALGCKVWDQNANENADWLANPFRSGADDLGPVYGVQWRQWPAYKLID 120 GFLRA+RSAADFRALGCKVWD NANENA WLANP+R G DDLG VYGVQWRQWP YK++D Sbjct: 61 GFLRASRSAADFRALGCKVWDANANENAQWLANPYRQGVDDLGDVYGVQWRQWPGYKVLD 120 Query: 121 AAHTTQIEAARSKGFAIVSSLRDEGVEKVLLYKAVDQLRECLDTIVNNPGSRRILFHGWN 180 A QI+ A +GF IV+ ++G KVLLYKA+DQLR+CLDTI+ NP RRILFH WN Sbjct: 121 AGADAQIDDATRRGFRIVTRFDEDGAPKVLLYKAIDQLRQCLDTIMENPADRRILFHAWN 180 Query: 181 CAVLDEVALPACHLLYQFLPNQSTGEISLCLYVRSNDIGLGTPFNLAEGAALLHLVARLT 240 AVLD++ALPACHLLYQFLPN + EISLCLY+RSND+GLGTPFNL EGAALL LV RLT Sbjct: 181 PAVLDQIALPACHLLYQFLPNATKREISLCLYIRSNDVGLGTPFNLTEGAALLELVGRLT 240 Query: 241 GYKPRWFSYFVGDAHIYENHIDMVKEQLTRAPYPLPQLEIADRVPEFARTGRYEPQWLEL 300 GY PRWF+YF+GDAHIYEN +DM++ QLTR PY P+LEIA+RVPE+A+TG Y P+WLE Sbjct: 241 GYTPRWFTYFIGDAHIYENQLDMLQRQLTREPYDSPRLEIAERVPEYAKTGVYAPEWLEQ 300 Query: 301 VEPSDFSLVNYQHHAPLTAPMAV 323 +EPSDFSLV Y+HH PLTAPMAV Sbjct: 301 IEPSDFSLVGYRHHEPLTAPMAV 323 >F0GAT3.1 F0GAT3_9BURK Thymidylate synthase EC=2.1.1.45 Length = 323 Score = 521 bits (1343), Expect = e-146, Method: Compositional matrix adjust. Identities = 236/323 (73%), Positives = 277/323 (85%) Query: 1 MKQYQDLIQDVLENGSWQDNRTGIRTLSIPGAMMRFDLQKGFPAVTTKRLAFKSVVGELC 60 MKQY DL++ +L+ G+WQ+NRTGIRT+S+PGAM+RFDLQ+GFPAVTTK+LAFKS +GEL Sbjct: 1 MKQYLDLVRTILDTGTWQENRTGIRTISMPGAMLRFDLQQGFPAVTTKKLAFKSAIGELV 60 Query: 61 GFLRATRSAADFRALGCKVWDQNANENADWLANPFRSGADDLGPVYGVQWRQWPAYKLID 120 GFLRA+RSAADFRALGCKVWD NANENA WLANP+R G DDLG VYGVQWRQWP YK++D Sbjct: 61 GFLRASRSAADFRALGCKVWDANANENAQWLANPYRQGVDDLGDVYGVQWRQWPGYKVLD 120 Query: 121 AAHTTQIEAARSKGFAIVSSLRDEGVEKVLLYKAVDQLRECLDTIVNNPGSRRILFHGWN 180 A QI A +GF IV+ ++G KVLLYKA+DQLR+CLDTI+ NP RRILFH WN Sbjct: 121 AGADAQIADATRRGFRIVTRFDEDGAPKVLLYKAIDQLRQCLDTIIENPSDRRILFHAWN 180 Query: 181 CAVLDEVALPACHLLYQFLPNQSTGEISLCLYVRSNDIGLGTPFNLAEGAALLHLVARLT 240 AVLD++ALPACHLLYQFLPN + EISLCLY+RSND+GLGTPFNL EGAALL LV RLT Sbjct: 181 PAVLDQIALPACHLLYQFLPNAAKREISLCLYIRSNDVGLGTPFNLTEGAALLSLVGRLT 240 Query: 241 GYKPRWFSYFVGDAHIYENHIDMVKEQLTRAPYPLPQLEIADRVPEFARTGRYEPQWLEL 300 GY PRWF+YF+GDAHIYEN +DM+++QLTR PY P+LEIA+RVP++A+TG Y P+WLE Sbjct: 241 GYTPRWFTYFIGDAHIYENQLDMLQQQLTREPYESPRLEIAERVPDYAKTGVYAPEWLER 300 Query: 301 VEPSDFSLVNYQHHAPLTAPMAV 323 VEPSDFSLV Y+HH PLTAPMAV Sbjct: 301 VEPSDFSLVGYRHHEPLTAPMAV 323