BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0006.0004.p (279 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8IPK1.1 D8IPK1_HERSS Hydroxyacylglutathione hydrolase EC=3.1.2.6 538 e-151 F1VTY2.1 F1VTY2_9BURK Hydroxyacylglutathione hydrolase 323 1e-86 A6SXA2.1 A6SXA2_JANMA Hydroxyacylglutathione hydrolase EC=3.1.2.6 316 2e-84 A4G7G5.1 GLO2_HERAR Hydroxyacylglutathione hydrolase EC=3.1.2.6 312 3e-83 A1X1Q6.1 A1X1Q6_9BURK Hydroxyacylglutathione hydrolase EC=3.1.2.6 297 1e-78 C3XAF7.1 C3XAF7_OXAFO Hydroxyacylglutathione hydrolase EC=3.1.2.6 286 2e-75 C3X4A5.1 C3X4A5_OXAFO Hydroxyacylglutathione hydrolase EC=3.1.2.6 280 2e-73 C5T6J5.1 C5T6J5_ACIDE Hydroxyacylglutathione hydrolase EC=3.1.2.6 274 1e-71 A2SIU5.1 A2SIU5_METPP Hydroxyacylglutathione hydrolase 2 EC=3.1.2.6 273 1e-71 B2SZS7.1 B2SZS7_BURPP Hydroxyacylglutathione hydrolase EC=3.1.2.6 273 2e-71 >D8IPK1.1 D8IPK1_HERSS Hydroxyacylglutathione hydrolase EC=3.1.2.6 Length = 264 Score = 538 bits (1387), Expect = e-151, Method: Compositional matrix adjust. Identities = 261/264 (98%), Positives = 263/264 (99%) Query: 16 LDVLAVPAFDDNYLWIIHDGRYAAVVDPGDAVPVLAALQAEGLTLAAILLTHHHADHVGG 75 +DVLAVPAFDDNYLWIIHDGRYAAVVDPGDAVPVLAALQAEGLTLAAILLTHHHADHVGG Sbjct: 1 MDVLAVPAFDDNYLWIIHDGRYAAVVDPGDAVPVLAALQAEGLTLAAILLTHHHADHVGG 60 Query: 76 VVELARQAASDTFPIIPVYGPAREQSRIKGMTVPLHGNDQVDIAVLGLRLEVIEVPGHTL 135 VVELARQAASDTFPIIPVYGPAREQSRIKGMTVPLHGNDQVDIAVLGLRLEVIEVPGHT+ Sbjct: 61 VVELARQAASDTFPIIPVYGPAREQSRIKGMTVPLHGNDQVDIAVLGLRLEVIEVPGHTM 120 Query: 136 GHIAYHAPEQAMLFCGDTLFAGGCGRLFEGTPQQMVDSLRRLASLPGQTAVYCAHEYTLS 195 GHIAYHAPEQAMLFCGDTLFAGGCGRLFEGTPQQMVDSL RLASLPGQTAVYCAHEYTLS Sbjct: 121 GHIAYHAPEQAMLFCGDTLFAGGCGRLFEGTPQQMVDSLSRLASLPGQTAVYCAHEYTLS 180 Query: 196 NLKFAAEVEPGNAELHARITRERARRERGEPTVPTSIALERQTNPFLRATEKEILDSLQK 255 NLKFAAEVEPGNAELHARITRERARRERGEPTVPTSIALERQTNPFLRATEKEILDSLQK Sbjct: 181 NLKFAAEVEPGNAELHARITRERARRERGEPTVPTSIALERQTNPFLRATEKEILDSLQK 240 Query: 256 AGRLKELDEVSSFAALREWKNSYK 279 AGRLKELDEVSSFAALREWKNSYK Sbjct: 241 AGRLKELDEVSSFAALREWKNSYK 264 >F1VTY2.1 F1VTY2_9BURK Hydroxyacylglutathione hydrolase Length = 259 Score = 323 bits (829), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 161/265 (60%), Positives = 201/265 (75%), Gaps = 8/265 (3%) Query: 15 SLDVLAVPAFDDNYLWIIHDGRYAAVVDPGDAVPVLAALQAEGLTLAAILLTHHHADHVG 74 +L VL +PAFDDNYLW++HDG +AAVVDPGDA P+LAAL L+L AILLTHHHADHVG Sbjct: 3 TLQVLTIPAFDDNYLWLVHDGVHAAVVDPGDAGPILAALALHQLSLVAILLTHHHADHVG 62 Query: 75 GVVELARQAASDTFPIIPVYGPAREQSRIKGMTVPLHGNDQVDIAVLGLRLEVIEVPGHT 134 GV EL + A+ +PVYGP E +I +T PL D V + L +L V++VPGHT Sbjct: 63 GVPELLQHAS------VPVYGPRHE--KIPTITHPLVQGDTVVVPELQWQLGVLDVPGHT 114 Query: 135 LGHIAYHAPEQAMLFCGDTLFAGGCGRLFEGTPQQMVDSLRRLASLPGQTAVYCAHEYTL 194 GHIAY A + LFCGDTLFAGGCGRLFEGTP+QM SL++LA+LPG+T+V+CAHEYT+ Sbjct: 115 SGHIAYFAAAEEWLFCGDTLFAGGCGRLFEGTPEQMDASLQKLAALPGRTSVFCAHEYTM 174 Query: 195 SNLKFAAEVEPGNAELHARITRERARRERGEPTVPTSIALERQTNPFLRATEKEILDSLQ 254 +NL+FA VEPGN L RI RE+ +R+R PTVP++IALER+TNPFLR E +I SLQ Sbjct: 175 ANLRFAQAVEPGNVALQERIVREQDKRDRHIPTVPSTIALERETNPFLRWREADIRHSLQ 234 Query: 255 KAGRLKELDEVSSFAALREWKNSYK 279 +AG+L + ++ FAALR WKNSY+ Sbjct: 235 QAGKLGDDTGIAGFAALRAWKNSYR 259 >A6SXA2.1 A6SXA2_JANMA Hydroxyacylglutathione hydrolase EC=3.1.2.6 Length = 258 Score = 316 bits (809), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 158/263 (60%), Positives = 188/263 (71%), Gaps = 8/263 (3%) Query: 16 LDVLAVPAFDDNYLWIIHDGRYAAVVDPGDAVPVLAALQAEGLTLAAILLTHHHADHVGG 75 L VL VPAF+DNYLWIIHDG +AAVVDPGDA P+LAAL+A L+L AILLTHHH+DHVGG Sbjct: 4 LSVLTVPAFNDNYLWIIHDGVHAAVVDPGDAKPILAALEAHKLSLVAILLTHHHSDHVGG 63 Query: 76 VVELARQAASDTFPIIPVYGPAREQSRIKGMTVPLHGNDQVDIAVLGLRLEVIEVPGHTL 135 V L + +PV+ P ++ I +T PL D V I LGL L V+ VPGHTL Sbjct: 64 VSTLLQHFK------VPVFAPRKDP--IANVTQPLDEGDVVTIPELGLELSVLHVPGHTL 115 Query: 136 GHIAYHAPEQAMLFCGDTLFAGGCGRLFEGTPQQMVDSLRRLASLPGQTAVYCAHEYTLS 195 GHIAY A EQ LFCGDTLFAGGCGRLFEGTP QM+ SL +LA+LP T VYCAHEYT+S Sbjct: 116 GHIAYVAKEQGWLFCGDTLFAGGCGRLFEGTPTQMLASLDKLAALPDDTKVYCAHEYTIS 175 Query: 196 NLKFAAEVEPGNAELHARITRERARRERGEPTVPTSIALERQTNPFLRATEKEILDSLQK 255 NL+FA EP N L +R E+A+R++ PTVP++I LE+ TNPFLRA E I + Sbjct: 176 NLRFALAAEPANTALASRFEAEQAKRKQNIPTVPSNIGLEKSTNPFLRAREPAIAKQMVA 235 Query: 256 AGRLKELDEVSSFAALREWKNSY 278 GR K D V+ FAALREWKN++ Sbjct: 236 EGRAKNADPVTVFAALREWKNNF 258 >A4G7G5.1 GLO2_HERAR Hydroxyacylglutathione hydrolase EC=3.1.2.6 Length = 259 Score = 312 bits (800), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 160/266 (60%), Positives = 189/266 (71%), Gaps = 10/266 (3%) Query: 16 LDVLAVPAFDDNYLWIIHDGRYAAVVDPGDAVPVLAALQAEGLTLAAILLTHHHADHVGG 75 L VL VPAF+DNYLWIIHDG +AAVVDPGDA P+LAAL+ L+L AILLTHHHADHVGG Sbjct: 2 LSVLTVPAFNDNYLWIIHDGVHAAVVDPGDATPILAALEEHQLSLVAILLTHHHADHVGG 61 Query: 76 VVELARQAASDTFPIIPVYGPAREQSRIKGMTVPLHGNDQVDIAVLGLRLEVIEVPGHTL 135 V +L + +PV+ P ++ I ++ PL D V I L L L V+ VPGHTL Sbjct: 62 VAKLLQHFN------VPVFAPRKDP--IANVSHPLDDGDTVHIPELDLHLSVLAVPGHTL 113 Query: 136 GHIAYHAPEQAMLFCGDTLFAGGCGRLFEGTPQQMVDSLRRLASLPGQTAVYCAHEYTLS 195 GHIAY A EQ LFCGDTLFAGGCGRLFEGTP QM+ SL +LA+LP T VYCAHEYT+S Sbjct: 114 GHIAYVAAEQGWLFCGDTLFAGGCGRLFEGTPTQMLTSLEKLAALPDDTKVYCAHEYTIS 173 Query: 196 NLKFAAEVEPGNAELHARITRERARRERGEPTVPTSIALERQTNPFLRATEKEILDSLQK 255 NL+FA EP NA L R E+A+RE PTVP++I LE+ TNPFLRA E I D L Sbjct: 174 NLRFALAAEPDNAALAIRFKAEQAKREADIPTVPSTIGLEKSTNPFLRAREPAIADQLIA 233 Query: 256 AGRLKELDE--VSSFAALREWKNSYK 279 AGR+ E D+ V+ FAALR WKN ++ Sbjct: 234 AGRVNENDKGPVAVFAALRAWKNDFR 259 >A1X1Q6.1 A1X1Q6_9BURK Hydroxyacylglutathione hydrolase EC=3.1.2.6 Length = 269 Score = 297 bits (761), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 159/270 (58%), Positives = 191/270 (70%), Gaps = 14/270 (5%) Query: 15 SLDVLAVPAFDDNYLWIIHDGRYAAVVDPGDAVPVLAALQAEGLTLAAILLTHHHADHVG 74 +L VLAVPAF DNYLW+IHDGR+AAVVDPGDA+ +L ALQA LTL AILLTHHHADH G Sbjct: 8 ALSVLAVPAFADNYLWLIHDGRHAAVVDPGDAMAILDALQAHQLTLTAILLTHHHADHTG 67 Query: 75 GVVELARQAASDTFPIIPVYGPAREQSRIKGMTVPLHGNDQVDIAVLGLRLEVIEVPGHT 134 GV EL + A +PV+GP E I +T PL D + LGL++ VI+VPGHT Sbjct: 68 GVPELLQHFA------VPVFGPRNEA--ITAITEPLAEGDVAYVPELGLQMTVIDVPGHT 119 Query: 135 LGHIAY--HAPEQA---MLFCGDTLFAGGCGRLFEGTPQQMVDSLRRLASLPGQTAVYCA 189 GHIAY E++ LF GDTLFAGGCGRLFEGTP QM DSL +LA+LP T V+CA Sbjct: 120 KGHIAYVRQRDERSGAPWLFSGDTLFAGGCGRLFEGTPGQMADSLGKLAALPDDTEVFCA 179 Query: 190 HEYTLSNLKFAAEVEPGNAELHARITRERARRERGEPTVPTSIALERQTNPFLRATEKEI 249 HEYTLSNL+FA VEPGN L RI + +R++G TVP++IALE+ TNPFLR E I Sbjct: 180 HEYTLSNLRFANAVEPGNVALQERIAIDTEKRQQGLSTVPSTIALEKATNPFLRYREPAI 239 Query: 250 LDSLQKAGRL-KELDEVSSFAALREWKNSY 278 L SL+ G+L + V +FAALR WKN++ Sbjct: 240 LTSLKVEGKLASDASPVEAFAALRMWKNNF 269 >C3XAF7.1 C3XAF7_OXAFO Hydroxyacylglutathione hydrolase EC=3.1.2.6 Length = 265 Score = 286 bits (732), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 141/273 (51%), Positives = 190/273 (69%), Gaps = 11/273 (4%) Query: 7 PAQPDQKTSLDVLAVPAFDDNYLWIIHDGRYAAVVDPGDAVPVLAALQAEGLTLAAILLT 66 P+ DQ +L V +PAF+DNY+W+I + + A +VDPG+A PVLAALQ L L AI+LT Sbjct: 2 PSSTDQ--TLQVSPIPAFNDNYIWMIDNRKEAVIVDPGEAGPVLAALQKRSLKLCAIVLT 59 Query: 67 HHHADHVGGVVELARQAASDTFPIIPVYGPAREQSRIKGMTVPLHGNDQVDIAVL-GLRL 125 H H DH+GGV L ++ + +PVYGP + I+ +T P+ D V I L L+L Sbjct: 60 HRHEDHIGGVSRLLQEYS------VPVYGPRFDP--IESVTQPVQEGDIVTIFELDNLQL 111 Query: 126 EVIEVPGHTLGHIAYHAPEQAMLFCGDTLFAGGCGRLFEGTPQQMVDSLRRLASLPGQTA 185 V++VPGHT GHIAY+A ++ LFCGD LF GCGR+FEGTP+QM SL +LA+LP Sbjct: 112 SVLDVPGHTKGHIAYYAKKEKWLFCGDMLFGAGCGRMFEGTPEQMWTSLSKLAALPDDVE 171 Query: 186 VYCAHEYTLSNLKFAAEVEPGNAELHARITRERARRERGEPTVPTSIALERQTNPFLRAT 245 V+ HEYTLSNLKFA E+EP + L ARI + A+R R +PT+P++I LE+ TNPFLRA Sbjct: 172 VFAGHEYTLSNLKFAREIEPDSKALAARIKEDVAKRNRRQPTLPSTIGLEKATNPFLRAD 231 Query: 246 EKEILDSLQKAGRLKELDEVSSFAALREWKNSY 278 +E++ L+ G+LK+ D V++FAA+REWKN Y Sbjct: 232 REEVMKRLESLGKLKDHDPVNAFAAMREWKNKY 264 >C3X4A5.1 C3X4A5_OXAFO Hydroxyacylglutathione hydrolase EC=3.1.2.6 Length = 265 Score = 280 bits (715), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 140/273 (51%), Positives = 185/273 (67%), Gaps = 11/273 (4%) Query: 7 PAQPDQKTSLDVLAVPAFDDNYLWIIHDGRYAAVVDPGDAVPVLAALQAEGLTLAAILLT 66 P+ DQ +L V +PAF DNY+W+I + A VVDPG+A PVL+ L+ L L+AILLT Sbjct: 2 PSPTDQ--ALSVTPIPAFRDNYIWMIDNRTRAVVVDPGEAGPVLSTLKKRSLKLSAILLT 59 Query: 67 HHHADHVGGVVELARQAASDTFPIIPVYGPAREQSRIKGMTVPLHGNDQVDIAVL-GLRL 125 H H DH+GGV L ++A +PVYGP + + +T PL D V + L L L Sbjct: 60 HRHEDHIGGVARLLQEAD------VPVYGPRYDP--VVSVTHPLQEGDIVTLPDLDNLAL 111 Query: 126 EVIEVPGHTLGHIAYHAPEQAMLFCGDTLFAGGCGRLFEGTPQQMVDSLRRLASLPGQTA 185 V++VPGHT GHIAY+A ++ LFCGD LF GCGR+FEGTP+QM+ SL +LA+LP Sbjct: 112 SVLDVPGHTRGHIAYYAKKEKWLFCGDMLFGAGCGRMFEGTPEQMLASLSKLAALPDDVQ 171 Query: 186 VYCAHEYTLSNLKFAAEVEPGNAELHARITRERARRERGEPTVPTSIALERQTNPFLRAT 245 V+ HEYTLSNLKFA E+EPGN + R ++ ARR RG PT+P++I LE+ TNPFLRA Sbjct: 172 VFAGHEYTLSNLKFAREIEPGNEAIAERARQDLARRNRGRPTLPSTIGLEKATNPFLRAN 231 Query: 246 EKEILDSLQKAGRLKELDEVSSFAALREWKNSY 278 ++++ L++ G LK + V FAA+REWKNSY Sbjct: 232 REDVMKRLEELGHLKNRNPVDCFAAMREWKNSY 264 >C5T6J5.1 C5T6J5_ACIDE Hydroxyacylglutathione hydrolase EC=3.1.2.6 Length = 257 Score = 274 bits (700), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 147/268 (54%), Positives = 181/268 (67%), Gaps = 16/268 (5%) Query: 16 LDVLAVPAFDDNYLWIIHDGRYAAVVDPGDAVPVLAALQAEGLTLAAILLTHHHADHVGG 75 +++L +PAF DNY+W++HD R A VVDPGDA PVL ALQA+GL L AIL+THHHADHVGG Sbjct: 1 MNLLPLPAFTDNYIWMLHDTRQAIVVDPGDAAPVLHALQAQGLQLQAILVTHHHADHVGG 60 Query: 76 VVELARQAASDTFPIIPVYGPAREQSRIKGMTVPLHG-NDQVDIAVLGLRLEVIEVPGHT 134 V L + V+GPA EQ M PL D + VLGLR V++VPGHT Sbjct: 61 VPTLREATGAH------VFGPAGEQ-----MPEPLQRLADGDTVEVLGLRFSVLDVPGHT 109 Query: 135 LGHIAYHAPEQA---MLFCGDTLFAGGCGRLFEGTPQQMVDSLRRLASLPGQTAVYCAHE 191 GHIAY+ + A +LFCGDTLF+GGCGRLFEGTP QM+ SL RLA+LPG T V C HE Sbjct: 110 AGHIAYYCADLAGAPLLFCGDTLFSGGCGRLFEGTPAQMLASLDRLAALPGSTRVCCTHE 169 Query: 192 YTLSNLKFAAEVEPGNAELHARITRERARRERGEPTVPTSIALERQTNPFLRATEKEILD 251 YTLSNL+FA VEPGN L + + R R EPT+P++IALER+ NPFLR E + Sbjct: 170 YTLSNLRFARAVEPGNQALRDYSSHCESLRARQEPTLPSTIALEREINPFLRVREATVRA 229 Query: 252 SLQKA-GRLKELDEVSSFAALREWKNSY 278 + Q + D V+ FAALR+WKN++ Sbjct: 230 AAQGFDASPPQHDAVAVFAALRQWKNNF 257 >A2SIU5.1 A2SIU5_METPP Hydroxyacylglutathione hydrolase 2 EC=3.1.2.6 Length = 259 Score = 273 bits (699), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 145/267 (54%), Positives = 180/267 (67%), Gaps = 11/267 (4%) Query: 16 LDVLAVPAFDDNYLWIIHDGRYAAVVDPGDAVPVLAALQAEGLTLAAILLTHHHADHVGG 75 ++++AVPAF DNY+W++HDG A VVDPG+A PV AL L LAAI++THHH DHVGG Sbjct: 1 MNLIAVPAFTDNYIWMLHDGVSAIVVDPGEAAPVTRALDERSLKLAAIVVTHHHGDHVGG 60 Query: 76 VVELARQAASDTFPIIPVYGPAREQSRIKGMTVPLHGNDQVDIAVLGLRLEVIEVPGHTL 135 V L + P VYGPARE I +PL D +++ G R EVI+VPGHT Sbjct: 61 VDALRARLPDGRGP---VYGPARED--IPQPFLPLRDGDAIEL--FGTRFEVIDVPGHTA 113 Query: 136 GHIAYH---APEQAMLFCGDTLFAGGCGRLFEGTPQQMVDSLRRLASLPGQTAVYCAHEY 192 GHIAY A E +LFCGDTLF+GGCGRLFEGTP QM SL RLA+LPG T V CAHEY Sbjct: 114 GHIAYFGQPAGEAPILFCGDTLFSGGCGRLFEGTPAQMHASLSRLAALPGDTRVCCAHEY 173 Query: 193 TLSNLKFAAEVEPGNAELHARITRERARRERGEPTVPTSIALERQTNPFLRATEKEILDS 252 TL NLKFA VEPGNA+L + + + R+R PT+P+++A ERQ NPFLR T ++ S Sbjct: 174 TLGNLKFACAVEPGNADLIDYVAQCESLRQRDLPTLPSTVARERQVNPFLRVTSTQVRTS 233 Query: 253 LQKAGRLKELDEVSSFAALREWKNSYK 279 + G + D VS AALR+WKN ++ Sbjct: 234 ARAHGAAGD-DAVSVLAALRQWKNEFR 259 >B2SZS7.1 B2SZS7_BURPP Hydroxyacylglutathione hydrolase EC=3.1.2.6 Length = 263 Score = 273 bits (698), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 145/270 (53%), Positives = 181/270 (67%), Gaps = 12/270 (4%) Query: 14 TSLDVLAVPAFDDNYLWIIHDGRYAAVVDPGDAVPVLAALQAEGLTLAAILLTHHHADHV 73 +L+ + VPAFDDNY+W++ DGR+AAVVDPG+A PV A L G L+AILLTHHH DHV Sbjct: 2 NALEYVPVPAFDDNYIWVVSDGRHAAVVDPGEAAPVKAYLAKRGWRLSAILLTHHHQDHV 61 Query: 74 GGVVELARQAASDTFPIIPVYGPAREQSRIKGMTVPLHGNDQVDIAVLGLRLEVIEVPGH 133 GGV +L A +PVYGPA E I+ +T L D V IA L+L V++VPGH Sbjct: 62 GGVADLLNGQA------VPVYGPAGEA--IEHLTHRLKNGDHVSIAAPALKLSVLDVPGH 113 Query: 134 TLGHIAYH--APEQAM--LFCGDTLFAGGCGRLFEGTPQQMVDSLRRLASLPGQTAVYCA 189 T GHIAY A Q +FCGDTLFA GCGRLFEGTP+QM+ SL LA+LPG T V+CA Sbjct: 114 TSGHIAYFQAADPQGTPHVFCGDTLFACGCGRLFEGTPKQMLASLDSLAALPGATEVHCA 173 Query: 190 HEYTLSNLKFAAEVEPGNAELHARITRERARRERGEPTVPTSIALERQTNPFLRATEKEI 249 HEYTLSN++FA EPGNAEL A + R R PT+PT+IA ER NPFLRA + + Sbjct: 174 HEYTLSNIRFALACEPGNAELQAWRDKASELRARDVPTLPTTIAHERAVNPFLRAGDPAV 233 Query: 250 LDSLQKAGRLKELDEVSSFAALREWKNSYK 279 SL++ D +++F +REWKN ++ Sbjct: 234 QASLREQLHEAVPDRLTAFTLMREWKNRFR 263