BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0022.p (282 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J1E3.1 D8J1E3_HERSS Lysophospholipase protein EC=3.1.1.5 572 e-161 B5RWB8.1 B5RWB8_RALSO Lysophospholipase protein EC=3.1.1.5 213 2e-53 B5SL98.1 B5SL98_RALSO Lysophospholipase protein EC=3.1.1.5 213 3e-53 A3RZT2.1 A3RZT2_RALSO Lysophospholipase L2 EC=3.1.1.5 212 5e-53 D8NKQ1.1 D8NKQ1_RALSO Putative monoglyceride lipase (MGL) EC=3.1... 210 2e-52 D8NUZ0.1 D8NUZ0_RALSO Putative monoglyceride lipase (MGL) EC=3.1... 209 3e-52 Q8XU47.1 Q8XU47_RALSO Putative lysophospholipase protein EC=3.1.1.5 207 9e-52 D8N3P9.1 D8N3P9_RALSO Putative monoglyceride lipase (MGL) EC=3.1... 206 3e-51 C6BHA8.1 C6BHA8_RALP1 Alpha/beta hydrolase fold protein 206 3e-51 E2SXA7.1 E2SXA7_9RALS Lysophospholipase 205 7e-51 >D8J1E3.1 D8J1E3_HERSS Lysophospholipase protein EC=3.1.1.5 Length = 282 Score = 572 bits (1474), Expect = e-161, Method: Compositional matrix adjust. Identities = 281/282 (99%), Positives = 281/282 (99%) Query: 1 MIPLIAPQEHWIDADDGTRLFCRDWLLPGATAAVQMVHGLGEHGGRYFSLARLFNEAGLS 60 MIPLIAPQEHWIDADDGTRLFCRDWLLPGATAAVQMVHGLGEHGGRYFSLARLFNEAGLS Sbjct: 1 MIPLIAPQEHWIDADDGTRLFCRDWLLPGATAAVQMVHGLGEHGGRYFSLARLFNEAGLS 60 Query: 61 VRICDQRGHGNSGGVQGSLIRPDDLLRDLKLSFDDFSRRTECVPVLFGHSMGGLVAARFA 120 VRICDQRGHGNSGGVQGSLIRPDDLLRDLKLSFDDFSRRTECVPVLFGHSMGGLVAARFA Sbjct: 61 VRICDQRGHGNSGGVQGSLIRPDDLLRDLKLSFDDFSRRTECVPVLFGHSMGGLVAARFA 120 Query: 121 TGGYSPVRALALSSPALALDMKGWQKLLLAVSTAIAPGLALPTALPASRISHDPHEVRAY 180 TGGYSPVRALALSSPALALDMKGWQKLLLAVSTAIAPGLALPTALPASRISHDPHEVRAY Sbjct: 121 TGGYSPVRALALSSPALALDMKGWQKLLLAVSTAIAPGLALPTALPASRISHDPHEVRAY 180 Query: 181 RKDPLNHGKIAPRMLHFMLDAMRQVEREAGQFTRPVLLQVAGDDAFVAPRGSRAFFDALP 240 RKDPLNHGKIAPRMLHFMLDAMRQVEREAGQFTRPVLLQVAGDDAFVAPRGSRAFFDALP Sbjct: 181 RKDPLNHGKIAPRMLHFMLDAMRQVEREAGQFTRPVLLQVAGDDAFVAPRGSRAFFDALP 240 Query: 241 SGRKTLHWYEHAYHEIFNEEASLRAQAMQDLRNWLAQLPAQP 282 SGRKTLHWYEHAYHEIFNEEASLRAQAMQDLRNWLAQL AQP Sbjct: 241 SGRKTLHWYEHAYHEIFNEEASLRAQAMQDLRNWLAQLSAQP 282 >B5RWB8.1 B5RWB8_RALSO Lysophospholipase protein EC=3.1.1.5 Length = 286 Score = 213 bits (543), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 119/265 (44%), Positives = 151/265 (56%), Gaps = 4/265 (1%) Query: 16 DGTRLFCRDWL-LPGATA---AVQMVHGLGEHGGRYFSLARLFNEAGLSVRICDQRGHGN 71 DGT LF R WL PGA A V +VHG+ EH GRY +A++ E GL VR D RGHG Sbjct: 19 DGTELFVRTWLPAPGAGAPRGTVILVHGMAEHSGRYPHVAKVLCELGLRVRTFDLRGHGR 78 Query: 72 SGGVQGSLIRPDDLLRDLKLSFDDFSRRTECVPVLFGHSMGGLVAARFATGGYSPVRALA 131 SGG + +L PD+ L DL D +P + GHSMGGL+ ARF T PVR + Sbjct: 79 SGGSRMALDAPDNYLTDLAEILDAAVAEWNELPFVLGHSMGGLIVARFTTARIRPVRGVL 138 Query: 132 LSSPALALDMKGWQKLLLAVSTAIAPGLALPTALPASRISHDPHEVRAYRKDPLNHGKIA 191 LSSPAL L + ++ + +A+AP L +P + SR+S DP AYR DPL I+ Sbjct: 139 LSSPALRLKLPPGANVVRGLLSAVAPKLPVPNPVDPSRLSRDPSVGAAYRMDPLVQKTIS 198 Query: 192 PRMLHFMLDAMRQVEREAGQFTRPVLLQVAGDDAFVAPRGSRAFFDALPSGRKTLHWYEH 251 +L FML+A+ Q +R+A + P+LL G D V P GSR F P +TL W+E Sbjct: 199 ASVLEFMLNAITQAQRDAPRLEAPMLLMAGGADTIVDPSGSRDFCANAPEDLRTLAWFET 258 Query: 252 AYHEIFNEEASLRAQAMQDLRNWLA 276 AYHEIFNE R + LR WLA Sbjct: 259 AYHEIFNETEPTRGEVFGTLREWLA 283 >B5SL98.1 B5SL98_RALSO Lysophospholipase protein EC=3.1.1.5 Length = 286 Score = 213 bits (542), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 119/265 (44%), Positives = 151/265 (56%), Gaps = 4/265 (1%) Query: 16 DGTRLFCRDWL-LPGATA---AVQMVHGLGEHGGRYFSLARLFNEAGLSVRICDQRGHGN 71 DGT LF R WL PGA A V +VHG+ EH GRY +A++ E GL VR D RGHG Sbjct: 19 DGTELFVRTWLPAPGAGAPRGTVILVHGMAEHSGRYPHVAKVLCELGLRVRTFDLRGHGR 78 Query: 72 SGGVQGSLIRPDDLLRDLKLSFDDFSRRTECVPVLFGHSMGGLVAARFATGGYSPVRALA 131 SGG + +L PD+ L DL D +P + GHSMGGL+ ARF T PVR + Sbjct: 79 SGGPRMALDAPDNYLTDLAEILDAAVAEWNELPFVLGHSMGGLIVARFTTARIRPVRGVL 138 Query: 132 LSSPALALDMKGWQKLLLAVSTAIAPGLALPTALPASRISHDPHEVRAYRKDPLNHGKIA 191 LSSPAL L + ++ + +A+AP L +P + SR+S DP AYR DPL I+ Sbjct: 139 LSSPALRLKLPPGANVVRGLLSAVAPKLPVPNPVDPSRLSRDPSVGAAYRVDPLVQKTIS 198 Query: 192 PRMLHFMLDAMRQVEREAGQFTRPVLLQVAGDDAFVAPRGSRAFFDALPSGRKTLHWYEH 251 +L FML+A+ Q +R+A + P+LL G D V P GSR F P +TL W+E Sbjct: 199 ASVLEFMLNAITQAQRDAPRLEAPMLLMAGGADTIVDPSGSRDFCANAPEDLRTLAWFET 258 Query: 252 AYHEIFNEEASLRAQAMQDLRNWLA 276 AYHEIFNE R + LR WLA Sbjct: 259 AYHEIFNETEPTRGEVFGTLREWLA 283 >A3RZT2.1 A3RZT2_RALSO Lysophospholipase L2 EC=3.1.1.5 Length = 382 Score = 212 bits (539), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 119/265 (44%), Positives = 151/265 (56%), Gaps = 4/265 (1%) Query: 16 DGTRLFCRDWL-LPGATA---AVQMVHGLGEHGGRYFSLARLFNEAGLSVRICDQRGHGN 71 DGT LF R WL PGA A V +VHG+ EH GRY +A++ E GL VR D RGHG Sbjct: 115 DGTELFVRTWLPAPGAGAPRGTVILVHGMAEHSGRYPHVAKVLCELGLRVRTFDLRGHGR 174 Query: 72 SGGVQGSLIRPDDLLRDLKLSFDDFSRRTECVPVLFGHSMGGLVAARFATGGYSPVRALA 131 SGG + +L PD+ L DL D +P + GHSMGGL+ ARF T PVR + Sbjct: 175 SGGPRMALDAPDNYLTDLAEILDAAVAEWNELPFVLGHSMGGLIVARFTTARIRPVRGVL 234 Query: 132 LSSPALALDMKGWQKLLLAVSTAIAPGLALPTALPASRISHDPHEVRAYRKDPLNHGKIA 191 LSSPAL L + ++ + +A+AP L +P + SR+S DP AYR DPL I+ Sbjct: 235 LSSPALRLKLPPGANVVRGLLSAVAPKLPVPNPVDPSRLSRDPSVGAAYRVDPLVQKTIS 294 Query: 192 PRMLHFMLDAMRQVEREAGQFTRPVLLQVAGDDAFVAPRGSRAFFDALPSGRKTLHWYEH 251 +L FML+A+ Q +R+A + P+LL G D V P GSR F P +TL W+E Sbjct: 295 ASVLEFMLNAITQAQRDAPRLEAPMLLMAGGADTIVDPSGSRDFCANAPEDLRTLAWFET 354 Query: 252 AYHEIFNEEASLRAQAMQDLRNWLA 276 AYHEIFNE R + LR WLA Sbjct: 355 AYHEIFNETEPTRGEVFGTLREWLA 379 >D8NKQ1.1 D8NKQ1_RALSO Putative monoglyceride lipase (MGL) EC=3.1.1.23 Length = 286 Score = 210 bits (535), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 118/265 (44%), Positives = 150/265 (56%), Gaps = 4/265 (1%) Query: 16 DGTRLFCRDWL-LPGATA---AVQMVHGLGEHGGRYFSLARLFNEAGLSVRICDQRGHGN 71 DGT LF R WL P A A V +VHG+ EH GR+ +A++ E GL VR D RGHG Sbjct: 19 DGTELFVRTWLPAPEAGAPRGTVILVHGMAEHSGRHLHVAKVLCELGLRVRAFDLRGHGR 78 Query: 72 SGGVQGSLIRPDDLLRDLKLSFDDFSRRTECVPVLFGHSMGGLVAARFATGGYSPVRALA 131 SGG + +L PD+ L DL D +P + GHSMGGL+ ARF T PVR + Sbjct: 79 SGGPRMALDAPDNYLTDLAEILDAAVAEWNELPFVLGHSMGGLIVARFTTARIRPVRGVL 138 Query: 132 LSSPALALDMKGWQKLLLAVSTAIAPGLALPTALPASRISHDPHEVRAYRKDPLNHGKIA 191 LSSPAL L + ++ + +A+AP L +P + SR+SHDP AYR DPL I+ Sbjct: 139 LSSPALRLRLPPGANVVRGLLSAVAPKLPVPNPVDPSRLSHDPTVGAAYRADPLVQKTIS 198 Query: 192 PRMLHFMLDAMRQVEREAGQFTRPVLLQVAGDDAFVAPRGSRAFFDALPSGRKTLHWYEH 251 +L FML+A+ Q +R+A + P+LL G D V P GSR F P +TL W+E Sbjct: 199 ASVLEFMLNAITQAQRDAPRLEAPMLLMAGGSDTIVDPSGSRDFCANAPEDLRTLAWFET 258 Query: 252 AYHEIFNEEASLRAQAMQDLRNWLA 276 AYHEIFNE R LR WLA Sbjct: 259 AYHEIFNETEPTRGAVFGALREWLA 283 >D8NUZ0.1 D8NUZ0_RALSO Putative monoglyceride lipase (MGL) EC=3.1.1.23 Length = 286 Score = 209 bits (533), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 116/266 (43%), Positives = 152/266 (57%), Gaps = 6/266 (2%) Query: 16 DGTRLFCRDWLLPGATA-----AVQMVHGLGEHGGRYFSLARLFNEAGLSVRICDQRGHG 70 DGT LF R WL P A V +VHG+ EH GRY +A++ E GL VR D RGHG Sbjct: 19 DGTELFVRTWL-PACEAGAPRGTVILVHGMAEHSGRYPHVAKVLCELGLRVRAFDLRGHG 77 Query: 71 NSGGVQGSLIRPDDLLRDLKLSFDDFSRRTECVPVLFGHSMGGLVAARFATGGYSPVRAL 130 SGG + +L PD+ L DL D +P + GHSMGGL+ ARF T PVR + Sbjct: 78 KSGGPRMALDAPDNYLTDLAEILDATVAEWNEMPFVLGHSMGGLIVARFTTARVRPVRGV 137 Query: 131 ALSSPALALDMKGWQKLLLAVSTAIAPGLALPTALPASRISHDPHEVRAYRKDPLNHGKI 190 LSSPAL + + L + +AIAP L +P + SR+SHDP AYR DPL I Sbjct: 138 LLSSPALRIKLPPGANALRGLLSAIAPRLPVPNPVSPSRLSHDPAVGAAYRVDPLVQKTI 197 Query: 191 APRMLHFMLDAMRQVEREAGQFTRPVLLQVAGDDAFVAPRGSRAFFDALPSGRKTLHWYE 250 + +L FML+A+ Q +++A + P+LL G D V P GS+ F+ P +TL W+E Sbjct: 198 SASVLAFMLNAITQAQQDAPRLEAPMLLIAGGSDTIVDPSGSQDFYANAPEDLRTLAWFE 257 Query: 251 HAYHEIFNEEASLRAQAMQDLRNWLA 276 AYHE+FNE +R +A +R WLA Sbjct: 258 TAYHELFNEAEPMRGEAFGKMRAWLA 283 >Q8XU47.1 Q8XU47_RALSO Putative lysophospholipase protein EC=3.1.1.5 Length = 286 Score = 207 bits (528), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 116/266 (43%), Positives = 152/266 (57%), Gaps = 6/266 (2%) Query: 16 DGTRLFCRDWLLPGATA-----AVQMVHGLGEHGGRYFSLARLFNEAGLSVRICDQRGHG 70 DGT LF R WL P A V +VHG+ EH GRY +A++ E GL VR D RGHG Sbjct: 19 DGTELFVRTWL-PAPEAGEPRGTVILVHGMAEHSGRYPHVAQVLCELGLRVRAFDLRGHG 77 Query: 71 NSGGVQGSLIRPDDLLRDLKLSFDDFSRRTECVPVLFGHSMGGLVAARFATGGYSPVRAL 130 SGG + +L PD+ L DL D +P + GHSMGGL+ ARFAT PVR + Sbjct: 78 RSGGPRMALDAPDNYLTDLAEILDAVVAEWNEMPFVLGHSMGGLIVARFATARVRPVRGV 137 Query: 131 ALSSPALALDMKGWQKLLLAVSTAIAPGLALPTALPASRISHDPHEVRAYRKDPLNHGKI 190 LSSPAL L + +L + +A+AP L +P + +R+SHDP AYR DP I Sbjct: 138 LLSSPALRLKLPPGANAVLGLLSALAPKLPVPNPVDPARLSHDPSVGAAYRADPQVQKTI 197 Query: 191 APRMLHFMLDAMRQVEREAGQFTRPVLLQVAGDDAFVAPRGSRAFFDALPSGRKTLHWYE 250 + +L FML+A+ Q +++A + P+LL G D V P GSR F P +TL W+E Sbjct: 198 SASVLAFMLNAITQAQQDAPRLEAPMLLLAGGADTIVDPSGSRDFCAGAPEDLRTLAWFE 257 Query: 251 HAYHEIFNEEASLRAQAMQDLRNWLA 276 AYHE+FNE +R +A +R WLA Sbjct: 258 TAYHELFNEAEPMRGEAFGTMRAWLA 283 >D8N3P9.1 D8N3P9_RALSO Putative monoglyceride lipase (MGL) EC=3.1.1.23 Length = 286 Score = 206 bits (525), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 115/266 (43%), Positives = 153/266 (57%), Gaps = 6/266 (2%) Query: 16 DGTRLFCRDWLLPGATA-----AVQMVHGLGEHGGRYFSLARLFNEAGLSVRICDQRGHG 70 DGT LF R WL P A V +VHG+ EH GRY +A++ E GL VR D RGHG Sbjct: 19 DGTELFVRTWL-PAPEAGEPRGTVILVHGMAEHSGRYPHVAQVLCELGLRVRAFDLRGHG 77 Query: 71 NSGGVQGSLIRPDDLLRDLKLSFDDFSRRTECVPVLFGHSMGGLVAARFATGGYSPVRAL 130 SGG + +L PD+ L DL D +P + GHSMGGL+ ARFAT PVR + Sbjct: 78 RSGGPRMALDAPDNYLTDLAEILDAAVAEWNEMPFVLGHSMGGLIVARFATARVRPVRGV 137 Query: 131 ALSSPALALDMKGWQKLLLAVSTAIAPGLALPTALPASRISHDPHEVRAYRKDPLNHGKI 190 LSSPAL L + ++ + +A+AP L +P + +R+SHDP AYR DP I Sbjct: 138 LLSSPALRLKLPPGANVVRGLLSAVAPKLPVPNPVDPARLSHDPSVGAAYRADPQVQKTI 197 Query: 191 APRMLHFMLDAMRQVEREAGQFTRPVLLQVAGDDAFVAPRGSRAFFDALPSGRKTLHWYE 250 + +L FML+A+ Q +++A + P+LL +G D V P GSR F P +TL W+E Sbjct: 198 SASVLAFMLNAITQAQQDAPRLEAPMLLLASGADTIVDPSGSRDFCAGAPEDLRTLAWFE 257 Query: 251 HAYHEIFNEEASLRAQAMQDLRNWLA 276 AYHE+FNE +R +A +R WLA Sbjct: 258 TAYHELFNEAEPMRGEAFGAMRAWLA 283 >C6BHA8.1 C6BHA8_RALP1 Alpha/beta hydrolase fold protein Length = 289 Score = 206 bits (524), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 110/266 (41%), Positives = 151/266 (56%), Gaps = 4/266 (1%) Query: 16 DGTRLFCRDWLLPGATA----AVQMVHGLGEHGGRYFSLARLFNEAGLSVRICDQRGHGN 71 DGT L R WL T V +VHG+ EH GRY +A++ + GL VR D RGHG Sbjct: 22 DGTELLVRTWLPAPDTGEPRGTVILVHGMAEHSGRYPHVAKVLTDLGLRVRAFDLRGHGK 81 Query: 72 SGGVQGSLIRPDDLLRDLKLSFDDFSRRTECVPVLFGHSMGGLVAARFATGGYSPVRALA 131 SGG + +L D+ L DL D +P + GHSMGGL+ ARF T PVR + Sbjct: 82 SGGPRMALDAQDNYLTDLAEIVDAAVAEWHEMPFVLGHSMGGLIVARFTTARIRPVRGVL 141 Query: 132 LSSPALALDMKGWQKLLLAVSTAIAPGLALPTALPASRISHDPHEVRAYRKDPLNHGKIA 191 LSSPAL + + ++ + +AIAP L +P + +++SHDP AYR DPL G I+ Sbjct: 142 LSSPALRVKLPPGTGIVRGILSAIAPRLPVPNPVDPAKLSHDPSIAAAYRADPLVQGTIS 201 Query: 192 PRMLHFMLDAMRQVEREAGQFTRPVLLQVAGDDAFVAPRGSRAFFDALPSGRKTLHWYEH 251 +L FML+A+ Q +++A + P+LL G DA V P GSR F+ P +TL W+++ Sbjct: 202 ASLLEFMLNAITQAQQDAPRLEAPMLLMAGGADAIVDPSGSRDFYANAPEDLRTLAWFDN 261 Query: 252 AYHEIFNEEASLRAQAMQDLRNWLAQ 277 YHEIFNE LR++ + WLA Sbjct: 262 GYHEIFNEAEPLRSEVFGKMTEWLAS 287 >E2SXA7.1 E2SXA7_9RALS Lysophospholipase Length = 289 Score = 205 bits (521), Expect = 7e-51, Method: Compositional matrix adjust. Identities = 109/266 (40%), Positives = 152/266 (57%), Gaps = 4/266 (1%) Query: 16 DGTRLFCRDWLLPGATA----AVQMVHGLGEHGGRYFSLARLFNEAGLSVRICDQRGHGN 71 DGT L R WL T V +VHG+ EH GRY +A++ + GL VR D RGHG Sbjct: 22 DGTELLVRTWLPAPDTGEPRGTVILVHGMAEHSGRYPHVAKVLTDLGLRVRAFDLRGHGK 81 Query: 72 SGGVQGSLIRPDDLLRDLKLSFDDFSRRTECVPVLFGHSMGGLVAARFATGGYSPVRALA 131 SGG + +L D+ L DL D +P + GHSMGGL+ ARF T PVR + Sbjct: 82 SGGPRMALDAQDNYLTDLAEIVDAAVAEWHEMPFVLGHSMGGLIVARFTTARIRPVRGVL 141 Query: 132 LSSPALALDMKGWQKLLLAVSTAIAPGLALPTALPASRISHDPHEVRAYRKDPLNHGKIA 191 LSSPAL + + ++ + +A+AP LA+P + +++SHDP AYR DPL G I+ Sbjct: 142 LSSPALRVKLPPGAGIVRGLLSALAPKLAVPNPVDPAKLSHDPSIAAAYRADPLVQGTIS 201 Query: 192 PRMLHFMLDAMRQVEREAGQFTRPVLLQVAGDDAFVAPRGSRAFFDALPSGRKTLHWYEH 251 +L FML+A+ Q +++A + P+LL G D+ V P GSR F+ P +TL W+++ Sbjct: 202 ASLLEFMLNAITQAQQDAPRLEAPMLLMAGGADSIVDPSGSRDFYANAPEDLRTLAWFDN 261 Query: 252 AYHEIFNEEASLRAQAMQDLRNWLAQ 277 YHEIFNE LR++ + WLA Sbjct: 262 GYHEIFNEAEPLRSEVFGKMTEWLAS 287