BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0161.p (336 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J1C9.1 D8J1C9_HERSS GGDEF domain protein 680 0.0 E4RB73.1 E4RB73_PSEPB GGDEF domain-containing protein 133 4e-29 Q88HA8.1 Q88HA8_PSEPK GGDEF domain protein 132 6e-29 Q87YJ9.1 Q87YJ9_PSESM GGDEF domain protein 130 2e-28 E2MD98.1 E2MD98_PSESM GGDEF domain protein 130 2e-28 Q4ZVU0.1 Q4ZVU0_PSEU2 GGDEF 130 2e-28 Q1I9D7.1 Q1I9D7_PSEE4 Putative diguanylate cyclase (GGDEF domain) 129 7e-28 Q87VZ9.1 Q87VZ9_PSESM GGDEF domain protein 125 1e-26 B0KRM0.1 B0KRM0_PSEPG Diguanylate cyclase 123 4e-26 E2M7S1.1 E2M7S1_PSESM GGDEF domain protein 122 1e-25 >D8J1C9.1 D8J1C9_HERSS GGDEF domain protein Length = 346 Score = 680 bits (1754), Expect = 0.0, Method: Compositional matrix adjust. Identities = 334/336 (99%), Positives = 335/336 (99%) Query: 1 MPLTQQRIDEFHGLIRPLSIGLQATGFILFLTGWALAAPNYVYPWWEGAALTAGGLFLLY 60 MPLTQQRIDEFHGLIRPLSIGLQATGFILFLTGWALAAP+YVYPWWEGAALTAGGLFLLY Sbjct: 11 MPLTQQRIDEFHGLIRPLSIGLQATGFILFLTGWALAAPSYVYPWWEGAALTAGGLFLLY 70 Query: 61 LVSRPGWLVPASFMMIWLLAEGFAMLAQPSPNRAFFTCALGITFALVSAPMFARTRYYMV 120 LVSRPGWLVPASFMMIWLLAEGFAMLAQPSPNRAFFTCALGITFALVSAPMFARTRYYMV Sbjct: 71 LVSRPGWLVPASFMMIWLLAEGFAMLAQPSPNRAFFTCALGITFALVSAPMFARTRYYMV 130 Query: 121 AVCGMYLILGRGSFIDAEVVGDERWMLLLTLTVLGLGNFVNLTVKRQHVESLRLRKELEF 180 AVCGMYLILGRGSFIDAEVVGDERWMLLLTLTVLGLGNFVNLTVKRQHVESLRLRKELEF Sbjct: 131 AVCGMYLILGRGSFIDAEVVGDERWMLLLTLTVLGLGNFVNLTVKRQHVESLRLRKELEF 190 Query: 181 IAFKDPLTGIDNRRRFMQQLPIILQAGQPSDACFLMIDIDNFKKINDDFGHASGDEALIL 240 IAFKDPLTGIDNRRRFMQQLPIILQAGQPSDACFLMIDIDNFKKINDDFGHASGDEALIL Sbjct: 191 IAFKDPLTGIDNRRRFMQQLPIILQAGQPSDACFLMIDIDNFKKINDDFGHASGDEALIL 250 Query: 241 TARAMQSALSEGALGRMGGEEFGIALSGGGLAHAEQVAAKLLQEVRQIHIHARPLTVSIG 300 TARAMQSALSEGALGRMGGEEFGIALSGGGLAHAEQVAAKLLQEVRQIHIHARPLTVSIG Sbjct: 251 TARAMQSALSEGALGRMGGEEFGIALSGGGLAHAEQVAAKLLQEVRQIHIHARPLTVSIG 310 Query: 301 IARAADHSSVSKVLSAADQALYQAKRAGKDRYVVSA 336 IARA DHSSVSKVLSAADQALYQAKRAGKDRYVVSA Sbjct: 311 IARATDHSSVSKVLSAADQALYQAKRAGKDRYVVSA 346 >E4RB73.1 E4RB73_PSEPB GGDEF domain-containing protein Length = 363 Score = 133 bits (335), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 97/270 (35%), Positives = 138/270 (51%), Gaps = 30/270 (11%) Query: 64 RPGWLVPASFMMIWLLAEGFAMLAQPSPNRAFFTCALGITFALVSAPMFARTRYYMVAVC 123 RP WLV ++ +AM P +FF CA+ IT+ +++ F TR A+ Sbjct: 114 RPVWLVLGVSTVL------YAMSVLPVRRWSFF-CAMVITWVMLNP--FYHTRIEPDALE 164 Query: 124 GMYLILGRGSFIDAEVVGDERWMLLLTLTVLGLGNFVNLTVKRQHVESLRLRKELEFIAF 183 G LI + + L+ GL ++ L +++ + + L K L A+ Sbjct: 165 GAMLI---------------SYAVFLS----GLVSYSYLQIRKTKLHNFYLSKVLLEQAY 205 Query: 184 KDPLTGIDNRRRFMQQLPIILQAGQPSDACFLMIDIDNFKKINDDFGHASGDEALILTAR 243 D LT I NRR FM Q L+ S MIDIDNFK++ND FGH GDE L A Sbjct: 206 VDALTDIPNRRSFMAQADRQLRMA-TSGQYLAMIDIDNFKRVNDRFGHDVGDEVLKRVAL 264 Query: 244 AMQSALSEGALGRMGGEEFGIALSGGGLAHAEQVAAKLLQEVRQIHIHARPLTVSIGIAR 303 +++++++ A R+GGEEF I G AEQ A L Q VR+ P+T+SIG+A+ Sbjct: 265 HIKTSMADQAFARLGGEEFAIFFEGLDQQGAEQRVAALCQRVRE-DTGEHPVTISIGLAK 323 Query: 304 AADHSSVSKVLSAADQALYQAKRAGKDRYV 333 S++ L ADQALY+AK GKDR+V Sbjct: 324 INRGESLTTALVRADQALYEAKHTGKDRFV 353 >Q88HA8.1 Q88HA8_PSEPK GGDEF domain protein Length = 363 Score = 132 bits (333), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 97/270 (35%), Positives = 138/270 (51%), Gaps = 30/270 (11%) Query: 64 RPGWLVPASFMMIWLLAEGFAMLAQPSPNRAFFTCALGITFALVSAPMFARTRYYMVAVC 123 RP WLV ++ +AM P +FF CA+ IT+ +++ F TR A+ Sbjct: 114 RPVWLVLGVSTVL------YAMSVLPVRRWSFF-CAMVITWVMLNP--FYHTRIEPDALE 164 Query: 124 GMYLILGRGSFIDAEVVGDERWMLLLTLTVLGLGNFVNLTVKRQHVESLRLRKELEFIAF 183 G LI + + L+ GL ++ L +++ + + L K L A+ Sbjct: 165 GAMLI---------------SYAVFLS----GLVSYSYLQIRKAKLHNFYLSKVLLEQAY 205 Query: 184 KDPLTGIDNRRRFMQQLPIILQAGQPSDACFLMIDIDNFKKINDDFGHASGDEALILTAR 243 D LT I NRR FM Q L+ S MIDIDNFK++ND FGH GDE L A Sbjct: 206 VDALTDIPNRRSFMAQADRQLRMA-TSGQYLAMIDIDNFKRVNDRFGHDVGDEVLKRVAL 264 Query: 244 AMQSALSEGALGRMGGEEFGIALSGGGLAHAEQVAAKLLQEVRQIHIHARPLTVSIGIAR 303 +++++++ A R+GGEEF I G AEQ A L Q VR+ P+T+SIG+A+ Sbjct: 265 HIKTSMADQAFARLGGEEFAIFFEGLDQQGAEQRVAALCQRVRE-DAGEHPVTISIGLAK 323 Query: 304 AADHSSVSKVLSAADQALYQAKRAGKDRYV 333 S++ L ADQALY+AK GKDR+V Sbjct: 324 VDRGESLTTALVRADQALYEAKHTGKDRFV 353 >Q87YJ9.1 Q87YJ9_PSESM GGDEF domain protein Length = 355 Score = 130 bits (328), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 87/232 (37%), Positives = 116/232 (50%), Gaps = 4/232 (1%) Query: 100 LGITFALVSAPMFARTRYYMVAVCGMYLILGRGSFIDAEVVGDERWMLLLTLTVLGLGNF 159 + + L S + TR Y+ ++IL ID + +M+L ++ + LG Sbjct: 100 IALMIILCSTLLVVYTRDYLFVSVLSWIILSPAQGIDTDSAA-YVFMMLFFVSSIALGVV 158 Query: 160 VNLTVKRQHVESLRLRKELEFIAFKDPLTGIDNRRRFMQQLPIILQAGQPSDACFLMIDI 219 +N T R + L L ++ D LT I NRR M L + Q S FLM+DI Sbjct: 159 LNHTYTRTLRKVLTLESRFRELSLTDDLTDILNRRALM--LALDEQLANNSGGYFLMLDI 216 Query: 220 DNFKKINDDFGHASGDEALILTARAMQSALSEGALGRMGGEEFGIALSGGGLAHAEQVAA 279 DNFK IND FGH +GDE L L A +Q A GRMGGEEFG+ L G A Sbjct: 217 DNFKTINDQFGHDAGDEVLRLMASCLQQTPGSLAFGRMGGEEFGVILPVSGEPVACDYVL 276 Query: 280 KLLQEVRQIHIHARPLTVSIGIARAADHSSVSKVLSAADQALYQAKRAGKDR 331 +LL +R+ LT S G+A +S+ S+VL AD +YQAKR GKDR Sbjct: 277 RLLDTIRR-SPAVSSLTCSAGLADIDANSTSSQVLKTADINMYQAKREGKDR 327 >E2MD98.1 E2MD98_PSESM GGDEF domain protein Length = 355 Score = 130 bits (328), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 87/232 (37%), Positives = 116/232 (50%), Gaps = 4/232 (1%) Query: 100 LGITFALVSAPMFARTRYYMVAVCGMYLILGRGSFIDAEVVGDERWMLLLTLTVLGLGNF 159 + + L S + TR Y+ ++IL ID + +M+L ++ + LG Sbjct: 100 IALMIILCSTLLVVYTRDYLFVSVLSWIILSPAQGIDTDSAA-YVFMMLFFVSSIALGVV 158 Query: 160 VNLTVKRQHVESLRLRKELEFIAFKDPLTGIDNRRRFMQQLPIILQAGQPSDACFLMIDI 219 +N T R + L L ++ D LT I NRR M L + Q S FLM+DI Sbjct: 159 LNHTYTRTLRKVLTLESRFRELSLTDDLTDILNRRALM--LALDEQLANNSGGYFLMLDI 216 Query: 220 DNFKKINDDFGHASGDEALILTARAMQSALSEGALGRMGGEEFGIALSGGGLAHAEQVAA 279 DNFK IND FGH +GDE L L A +Q A GRMGGEEFG+ L G A Sbjct: 217 DNFKTINDQFGHDAGDEVLRLMASCLQQTPGSLAFGRMGGEEFGVILPVSGEPVACDYVL 276 Query: 280 KLLQEVRQIHIHARPLTVSIGIARAADHSSVSKVLSAADQALYQAKRAGKDR 331 +LL +R+ LT S G+A +S+ S+VL AD +YQAKR GKDR Sbjct: 277 RLLDTIRR-SPAVSSLTCSAGLADIDANSTSSQVLKTADINMYQAKREGKDR 327 >Q4ZVU0.1 Q4ZVU0_PSEU2 GGDEF Length = 354 Score = 130 bits (328), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 85/233 (36%), Positives = 117/233 (50%), Gaps = 4/233 (1%) Query: 99 ALGITFALVSAPMFARTRYYMVAVCGMYLILGRGSFIDAEVVGDERWMLLLTLTVLGLGN 158 ++ + L S + TR Y++ + IL +D + V +M L +T + LG+ Sbjct: 99 SVAVMIILCSTLLVVYTRDYLLVAVLAWCILSPAQGVDTDSVA-TLFMTLFFITSVSLGS 157 Query: 159 FVNLTVKRQHVESLRLRKELEFIAFKDPLTGIDNRRRFMQQLPIILQAGQPSDACFLMID 218 +N T R L L + ++ D LT I NRR MQ L S FLM+D Sbjct: 158 VLNHTYTRTLRTVLSLEHQFRELSMTDDLTAILNRRALMQALDN--HVLNNSAGYFLMLD 215 Query: 219 IDNFKKINDDFGHASGDEALILTARAMQSALSEGALGRMGGEEFGIALSGGGLAHAEQVA 278 ID+FK IND FGH +GD+AL + A +Q + A GRMGGEEFG+ L A Sbjct: 216 IDDFKTINDQFGHDAGDQALRVMAGCLQKTVGSLAFGRMGGEEFGVILPMCSEDDARDYV 275 Query: 279 AKLLQEVRQIHIHARPLTVSIGIARAADHSSVSKVLSAADQALYQAKRAGKDR 331 LL+ +R+ + PLT S G+A + S VL AD LY+AKR GKDR Sbjct: 276 LDLLECIRK-SLAVSPLTCSAGLADIPAAADSSAVLKTADINLYKAKRGGKDR 327 >Q1I9D7.1 Q1I9D7_PSEE4 Putative diguanylate cyclase (GGDEF domain) Length = 362 Score = 129 bits (324), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 98/275 (35%), Positives = 140/275 (50%), Gaps = 32/275 (11%) Query: 61 LVSRPGWLVPASFMMIWLLAEGFAMLAQPSPNRAFFTCALGITFALVSAPMFARTRYYMV 120 +V RP WLV +++ ++ P +FF CA+GIT+ +++ P F TR ++ Sbjct: 111 IVLRPVWLVLGVSTVLYTVS------VLPVRRWSFF-CAMGITWLMLN-PFF-HTRIALL 161 Query: 121 AVCGMYLILGRGSFIDAEVVGDERWMLLLTLTVLGLGNFVNLTVKRQHVESLRLRKELEF 180 + G L S+ L + GL + L +++ + + L K L Sbjct: 162 ELEGAMLF----SY---------------ALCLSGLVTYSYLRLRQAKLHNFYLTKVLLE 202 Query: 181 IAFKDPLTGIDNRRRFMQQLPIILQAGQPSDACFL-MIDIDNFKKINDDFGHASGDEALI 239 A+ D LT I NRR FM + LQ P FL MIDIDNFKK+ND FGH GDE L Sbjct: 203 QAYVDALTEIPNRRSFMAKAEKQLQQAGPGQ--FLAMIDIDNFKKVNDRFGHDIGDEVLK 260 Query: 240 LTARAMQSALSEGALGRMGGEEFGIALSGGGLAHAEQVAAKLLQEVRQIHIHARPLTVSI 299 A +++A+ + R+GGEEF I G AE+ L Q VR+ P+T+SI Sbjct: 261 RVAGHIKAAMVGFEIARLGGEEFAIFFQGLNEQGAEEQVGALCQRVRE-DAAEHPVTISI 319 Query: 300 GIARAADHSSVSKVLSAADQALYQAKRAGKDRYVV 334 G+ R +++ L ADQALY+AK GKDR+VV Sbjct: 320 GLTRVDSGDTLTLALIRADQALYEAKHTGKDRFVV 354 >Q87VZ9.1 Q87VZ9_PSESM GGDEF domain protein Length = 366 Score = 125 bits (313), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 83/255 (32%), Positives = 131/255 (51%), Gaps = 7/255 (2%) Query: 78 LLAEGFAMLAQPSPNRAFFTCALGITFALVSAPMFARTRYYMVAVCGMYLI--LGRGSFI 135 LLA GF L P F L IT A+ SA +F + Y+++ ++L+ L + Sbjct: 79 LLATGFFYLMDGDPEINIFALPLTITLAISSALLFVKFLDYLLSAVFVWLLTWLCWQEGV 138 Query: 136 DAEVVGDERWMLLLTLTVLGLGNFVNLTVKRQHVESLRLRKELEFIAFKDPLTGIDNRRR 195 E+ G W + + + +G+ +N++ + L L + +A D LT I NRR Sbjct: 139 YGEI-GIYVW--IFCVASVCIGSVLNISYIKTLRAVLSLESKFRELAETDYLTSIPNRRA 195 Query: 196 FMQQLPIILQAGQPSDACFLMIDIDNFKKINDDFGHASGDEALILTARAMQSALSEGALG 255 FM+ +++ G+ +M+DIDNFK IND GH GD L A +++ G Sbjct: 196 FMESFDSLIKGGES--GYLIMLDIDNFKLINDRHGHEIGDRILCSMAACLRATSGSHCAG 253 Query: 256 RMGGEEFGIALSGGGLAHAEQVAAKLLQEVRQIHIHARPLTVSIGIARAADHSSVSKVLS 315 R+GGEEFG+ ++GG A +LL+ VR + S+G+ R + S++S+ LS Sbjct: 254 RIGGEEFGVLITGGDELTACDYILRLLETVRANFDPPYNYSCSVGMVRFSAASTMSEALS 313 Query: 316 AADQALYQAKRAGKD 330 AD+++Y AKR GKD Sbjct: 314 MADKSMYIAKRNGKD 328 >B0KRM0.1 B0KRM0_PSEPG Diguanylate cyclase Length = 363 Score = 123 bits (309), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 71/180 (39%), Positives = 102/180 (56%), Gaps = 2/180 (1%) Query: 155 GLGNFVNLTVKRQHVESLRLRKELEFIAFKDPLTGIDNRRRFMQQLPIILQAGQPSDACF 214 GL + L ++ + + L + L A+ D LT I NRR FM + L+ P Sbjct: 177 GLITYSYLQTRKAKLHNFYLSRVLLEQAYVDALTEIPNRRSFMAKTEQQLKLATPGQ-YL 235 Query: 215 LMIDIDNFKKINDDFGHASGDEALILTARAMQSALSEGALGRMGGEEFGIALSGGGLAHA 274 M+DIDNFKK+ND FGH GDE L A +++A+ + R+GGEEF I L G A Sbjct: 236 AMVDIDNFKKVNDRFGHDIGDEVLRRVALHIKAAMVDSEFARLGGEEFAIFLEGLDQQGA 295 Query: 275 EQVAAKLLQEVRQIHIHARPLTVSIGIARAADHSSVSKVLSAADQALYQAKRAGKDRYVV 334 EQ L++ VR+ P+T+SIG+A+ + +++ L ADQALY+AK GKDR+V+ Sbjct: 296 EQQMEALVRRVRE-DAGTHPVTISIGLAQVSAGDTLTMALIKADQALYEAKHTGKDRFVL 354 >E2M7S1.1 E2M7S1_PSESM GGDEF domain protein Length = 366 Score = 122 bits (305), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 81/254 (31%), Positives = 130/254 (51%), Gaps = 5/254 (1%) Query: 78 LLAEGFAMLAQPSPNRAFFTCALGITFALVSAPMFARTRYYMVAVCGMYLILGRGSFIDA 137 LLA GF L P F L IT A+ SA +F + Y+++ ++L+ F Sbjct: 79 LLATGFFYLMDGDPEINIFALPLTITLAISSALLFVKFLDYLLSAVFVWLL--TWLFWQE 136 Query: 138 EVVGD-ERWMLLLTLTVLGLGNFVNLTVKRQHVESLRLRKELEFIAFKDPLTGIDNRRRF 196 V G+ ++ + + + +G+ +N++ + L L + +A D LT I NRR F Sbjct: 137 GVYGEIGIYVWIFCVASVCIGSVLNISYIKTLRAVLSLESKFRELAETDYLTSIPNRRAF 196 Query: 197 MQQLPIILQAGQPSDACFLMIDIDNFKKINDDFGHASGDEALILTARAMQSALSEGALGR 256 M+ +++ G+ +M++IDNFK IND GH GD L A +++ GR Sbjct: 197 MESFDSLIKGGE--SGYLIMLNIDNFKLINDRHGHEIGDRILCSMAACLRATSGSHCAGR 254 Query: 257 MGGEEFGIALSGGGLAHAEQVAAKLLQEVRQIHIHARPLTVSIGIARAADHSSVSKVLSA 316 +GGEEFG+ ++GG A +LL+ VR + S G+ R + S++S+ LS Sbjct: 255 IGGEEFGVLITGGDELTACDYILRLLETVRANFDPPYNYSCSAGMVRFSAASTMSEALSM 314 Query: 317 ADQALYQAKRAGKD 330 AD+++Y AKR GKD Sbjct: 315 ADKSMYIAKRNGKD 328