BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0096.p (526 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J165.1 D8J165_HERSS D-galactarate dehydratase protein EC=4.2.1.42 1071 0.0 Q46UY6.1 Q46UY6_CUPPJ Galactarate dehydratase EC=4.2.1.42 845 0.0 Q1LE30.1 Q1LE30_RALME Galactarate dehydratase EC=4.2.1.42 843 0.0 A1VMN3.1 A1VMN3_POLNA Galactarate dehydratase EC=4.2.1.42 836 0.0 E6V7T9.1 E6V7T9_VARPD Galactarate dehydratase EC=4.2.1.42 834 0.0 B3R923.1 B3R923_CUPTR (D)-galactarate dehydrogenase EC=4.2.1.42 833 0.0 Q128M4.1 Q128M4_POLSJ Galactarate dehydratase EC=4.2.1.42 831 0.0 Q0K2L8.1 Q0K2L8_CUPNH Probable D-galactarate dehydratase EC=4.2.... 829 0.0 C5CU21.1 C5CU21_VARPS Galactarate dehydratase EC=4.2.1.42 829 0.0 A2WGM0.1 A2WGM0_9BURK Altronate dehydratase 817 0.0 >D8J165.1 D8J165_HERSS D-galactarate dehydratase protein EC=4.2.1.42 Length = 522 Score = 1072 bits (2771), Expect = 0.0, Method: Compositional matrix adjust. Identities = 520/522 (99%), Positives = 520/522 (99%) Query: 5 MSTDTSASQASAPRYIMMNDTDNVAIVVNDGGLPAGTVFPDGLTLVDRVPQGHKIALRDL 64 MSTDTSASQASAPRYIMMNDTDNVAIVVNDGGLPAGTVFPDGLTLVDRVPQGHKIALRDL Sbjct: 1 MSTDTSASQASAPRYIMMNDTDNVAIVVNDGGLPAGTVFPDGLTLVDRVPQGHKIALRDL 60 Query: 65 KQGEVIVRYDVAIGYAVRDIPKGSWIEESLVQMPPARELDNLPIATKKPAPQPPLEGYTF 124 KQGE IVRYDVAIGYAVRDIPKG WIEESLVQMPPARELDNLPIATKKPAPQPPLEGYTF Sbjct: 61 KQGEAIVRYDVAIGYAVRDIPKGGWIEESLVQMPPARELDNLPIATKKPAPQPPLEGYTF 120 Query: 125 EGYRNADGSVGTRNLLAITTTVQCVAGVVEHAVKRIRAELLPKYPNVEDVVALEHTYGCG 184 EGYRNADGSVGTRNLLAITTTVQCVAGVVEHAVKRIRAELLPKYPNVEDVVALEHTYGCG Sbjct: 121 EGYRNADGSVGTRNLLAITTTVQCVAGVVEHAVKRIRAELLPKYPNVEDVVALEHTYGCG 180 Query: 185 VAIDAPNAGIPIRTLRNISLNPNFGGQAMVVSLGCEKLQPNRLLPENMIPIHKQGEPYVV 244 VAIDAPNAGIPIRTLRNISLNPNFGGQAMVVSLGCEKLQPNRLLPENMIPIHKQGEPYVV Sbjct: 181 VAIDAPNAGIPIRTLRNISLNPNFGGQAMVVSLGCEKLQPNRLLPENMIPIHKQGEPYVV 240 Query: 245 CLQDAEHVGFNSMIDSIMNMAEARLTELNKRRRETCPASDLVVGVQCGGSDAFSGVTANP 304 CLQDAEHVGFNSMIDSIMNMAEARLTELNKRRRETCPASDLVVGVQCGGSDAFSGVTANP Sbjct: 241 CLQDAEHVGFNSMIDSIMNMAEARLTELNKRRRETCPASDLVVGVQCGGSDAFSGVTANP 300 Query: 305 AVGFATDLLVRAGASVMFSEVTEVRDGIDQLTSRAVNEEVAQAMIREMDWYDNYLKQGGV 364 AVGFATDLLVRAGASVMFSEVTEVRDGIDQLTSRAVNEEVAQAMIREMDWYDNYLKQGGV Sbjct: 301 AVGFATDLLVRAGASVMFSEVTEVRDGIDQLTSRAVNEEVAQAMIREMDWYDNYLKQGGV 360 Query: 365 DRSANTTPGNKKGGLANIVEKAMGSIVKSGSSPISGVLSPGDKLQQKGLIYAATPASDFI 424 DRSANTTPGNKKGGLANIVEKAMGSIVKSGSSPISGVLSPGDKLQQKGLIYAATPASDFI Sbjct: 361 DRSANTTPGNKKGGLANIVEKAMGSIVKSGSSPISGVLSPGDKLQQKGLIYAATPASDFI 420 Query: 425 CGTLQLAAGMNLHIFTTGRGTPYGLAAVPVIKVATRNDLARRWHDLMDVNAGRIASGEAS 484 CGTLQLAAGMNLHIFTTGRGTPYGLAAVPVIKVATRNDLARRWHDLMDVNAGRIASGEAS Sbjct: 421 CGTLQLAAGMNLHIFTTGRGTPYGLAAVPVIKVATRNDLARRWHDLMDVNAGRIASGEAS 480 Query: 485 IEDVGWELFQLMLDVASGKKRTWAEQWKLHNALTLFNPAPVT 526 IEDVGWELFQLMLDVASGKKRTWAEQWKLHNALTLFNPAPVT Sbjct: 481 IEDVGWELFQLMLDVASGKKRTWAEQWKLHNALTLFNPAPVT 522 >Q46UY6.1 Q46UY6_CUPPJ Galactarate dehydratase EC=4.2.1.42 Length = 524 Score = 845 bits (2183), Expect = 0.0, Method: Compositional matrix adjust. Identities = 410/519 (78%), Positives = 456/519 (87%), Gaps = 4/519 (0%) Query: 12 SQA-SAPRYIMMNDTDNVAIVVNDGGLPAGTVFPDGLTLVDRVPQGHKIALRDLKQGEVI 70 SQA AP YI ++ DNVAIV NDGGLPAG FP GL L + VPQGHK+AL DLKQG+ + Sbjct: 6 SQAVKAPLYIRIHPEDNVAIVANDGGLPAGAAFPCGLVLQEAVPQGHKVALSDLKQGDAV 65 Query: 71 VRYDVAIGYAVRDIPKGSWIEESLVQMPPARELDNLPIATKKPAPQPPLEGYTFEGYRNA 130 VRY+V IGYA++D+P+GSW+ E +++MP A L +LPI T+ PAP PPLEGYTFEG+RN Sbjct: 66 VRYNVVIGYALKDLPRGSWVNERVIEMPVAPGLTDLPIGTRVPAPLPPLEGYTFEGFRNP 125 Query: 131 DGSVGTRNLLAITTTVQCVAGVVEHAVKRIRAELLPKYPNVEDVVALEHTYGCGVAIDAP 190 DGSVGTRN+LAITTTVQCV+GVVEHAV+RIR ELLP+YPNV+DVV LEHTYGCGVAIDAP Sbjct: 126 DGSVGTRNILAITTTVQCVSGVVEHAVRRIREELLPRYPNVDDVVGLEHTYGCGVAIDAP 185 Query: 191 NAGIPIRTLRNISLNPNFGGQAMVVSLGCEKLQPNRLLPENMIPIHK-QGEPYV--VCLQ 247 +A IPIRTLRNI+LNPNFGG AM+VSLGCEKLQP+RL+P IPI GE V VCLQ Sbjct: 186 DAVIPIRTLRNIALNPNFGGTAMMVSLGCEKLQPDRLMPAGTIPIQTGAGEVQVGVVCLQ 245 Query: 248 DAEHVGFNSMIDSIMNMAEARLTELNKRRRETCPASDLVVGVQCGGSDAFSGVTANPAVG 307 D +HVGF SMI SIM MAE L LN RRRETCP SDLVVGVQCGGSDAFSGVTANPAVG Sbjct: 246 DEQHVGFASMIASIMTMAETHLERLNARRRETCPVSDLVVGVQCGGSDAFSGVTANPAVG 305 Query: 308 FATDLLVRAGASVMFSEVTEVRDGIDQLTSRAVNEEVAQAMIREMDWYDNYLKQGGVDRS 367 FATDLLVRAGA+VMFSEVTEVRDGIDQLT+RA EVA AMIREM WYD YL++G VDRS Sbjct: 306 FATDLLVRAGAAVMFSEVTEVRDGIDQLTARAATPEVADAMIREMAWYDRYLERGRVDRS 365 Query: 368 ANTTPGNKKGGLANIVEKAMGSIVKSGSSPISGVLSPGDKLQQKGLIYAATPASDFICGT 427 ANTTPGNKKGGL+NIVEKAMGSI+KSG +PISGVLSPG+KL+QKGLIYAATPASDFICGT Sbjct: 366 ANTTPGNKKGGLSNIVEKAMGSIIKSGRAPISGVLSPGEKLKQKGLIYAATPASDFICGT 425 Query: 428 LQLAAGMNLHIFTTGRGTPYGLAAVPVIKVATRNDLARRWHDLMDVNAGRIASGEASIED 487 LQLAAGMNLH+FTTGRGTPYGLA VPVIKVATR+DLARRWHDLMDVNAGRIA+GEA+IED Sbjct: 426 LQLAAGMNLHVFTTGRGTPYGLAEVPVIKVATRSDLARRWHDLMDVNAGRIATGEATIED 485 Query: 488 VGWELFQLMLDVASGKKRTWAEQWKLHNALTLFNPAPVT 526 VGWELF+LM+DVASG+K+TWAE KLHNAL LFNPAPVT Sbjct: 486 VGWELFRLMIDVASGRKKTWAEHHKLHNALALFNPAPVT 524 >Q1LE30.1 Q1LE30_RALME Galactarate dehydratase EC=4.2.1.42 Length = 530 Score = 843 bits (2179), Expect = 0.0, Method: Compositional matrix adjust. Identities = 407/529 (76%), Positives = 462/529 (87%), Gaps = 5/529 (0%) Query: 3 TSMSTDTSASQAS--APRYIMMNDTDNVAIVVNDGGLPAGTVFPDGLTLVDRVPQGHKIA 60 + +S + QA+ AP YI ++ DNVAIV NDGGLPAG+VFP GLTLV+RVPQGHK+A Sbjct: 2 SDLSVQNAQGQAAERAPLYIRIHANDNVAIVANDGGLPAGSVFPCGLTLVERVPQGHKVA 61 Query: 61 LRDLKQGEVIVRYDVAIGYAVRDIPKGSWIEESLVQMPPARELDNLPIATKKPAPQPPLE 120 L DLK+G+ + RY+V IGYA++D+P+G+W+ E +++MP A L +LPI T+ P P PPLE Sbjct: 62 LVDLKKGDAVTRYNVTIGYALQDLPRGAWVNERVIEMPTAPGLTDLPIGTRVPEPLPPLE 121 Query: 121 GYTFEGYRNADGSVGTRNLLAITTTVQCVAGVVEHAVKRIRAELLPKYPNVEDVVALEHT 180 GYTFEG+RN DGSVGTRN+LAITTTVQCV+GVVEHAV RI+ ELLP+YPNV+DV+ LEHT Sbjct: 122 GYTFEGFRNPDGSVGTRNILAITTTVQCVSGVVEHAVHRIKTELLPRYPNVDDVIGLEHT 181 Query: 181 YGCGVAIDAPNAGIPIRTLRNISLNPNFGGQAMVVSLGCEKLQPNRLLPENMIPIHK-QG 239 YGCGVAIDAP+A +PIRTLRNI+LNPNFGG AM+VSLGCEKLQP RL+P IPI G Sbjct: 182 YGCGVAIDAPDAIVPIRTLRNIALNPNFGGTAMMVSLGCEKLQPERLMPPGTIPIQTGAG 241 Query: 240 EPYV--VCLQDAEHVGFNSMIDSIMNMAEARLTELNKRRRETCPASDLVVGVQCGGSDAF 297 E V VCLQD +HVGF SMIDSIM MAE L LN R+RET P S+LVVGVQCGGSDAF Sbjct: 242 EVQVGVVCLQDDKHVGFASMIDSIMAMAETHLQTLNARKRETVPVSELVVGVQCGGSDAF 301 Query: 298 SGVTANPAVGFATDLLVRAGASVMFSEVTEVRDGIDQLTSRAVNEEVAQAMIREMDWYDN 357 SGVTANPAVGFATDLLVRAGA+VMFSEVTEVRDGIDQLT+RA EVA+AMIREMDWYD Sbjct: 302 SGVTANPAVGFATDLLVRAGATVMFSEVTEVRDGIDQLTARAATPEVAEAMIREMDWYDR 361 Query: 358 YLKQGGVDRSANTTPGNKKGGLANIVEKAMGSIVKSGSSPISGVLSPGDKLQQKGLIYAA 417 YL +G VDRSANTTPGNKKGGL+NIVEKAMGSIVKSGS+PISGV+SPG+K++QKGLIYAA Sbjct: 362 YLDRGRVDRSANTTPGNKKGGLSNIVEKAMGSIVKSGSAPISGVVSPGEKVKQKGLIYAA 421 Query: 418 TPASDFICGTLQLAAGMNLHIFTTGRGTPYGLAAVPVIKVATRNDLARRWHDLMDVNAGR 477 TPASDFICGTLQLAAGMNLHIFTTGRGTPYGLA VPVIKVATR+DLARRWHDLMDVNAGR Sbjct: 422 TPASDFICGTLQLAAGMNLHIFTTGRGTPYGLAEVPVIKVATRSDLARRWHDLMDVNAGR 481 Query: 478 IASGEASIEDVGWELFQLMLDVASGKKRTWAEQWKLHNALTLFNPAPVT 526 IA+GEA+IEDVGWELF LM+DVASG+K+TWAE KLHNAL LFNPAPVT Sbjct: 482 IATGEATIEDVGWELFHLMIDVASGRKQTWAEHHKLHNALALFNPAPVT 530 >A1VMN3.1 A1VMN3_POLNA Galactarate dehydratase EC=4.2.1.42 Length = 532 Score = 836 bits (2160), Expect = 0.0, Method: Compositional matrix adjust. Identities = 409/531 (77%), Positives = 456/531 (85%), Gaps = 14/531 (2%) Query: 10 SASQASAPRYIMMNDTDNVAIVVNDGGLPAGTVFPDGLTLVDRVPQGHKIALRDLKQGEV 69 +A +S PRYI+M++ DNVAIVVNDGGLPAGTVF GLTL D+VPQGHK+AL DL QG Sbjct: 2 TALPSSQPRYILMHEADNVAIVVNDGGLPAGTVFASGLTLRDKVPQGHKVALVDLPQGST 61 Query: 70 IVRYDVAIGYAVRDIPKGSWIEESLVQMPPARELDNLPIATKKPAPQPPLEGYTFEGYRN 129 + RY+V IGYA++DIP GSW+ E L+ MP AR LDNLPIAT KP P PPLEGYTFEGYRN Sbjct: 62 VRRYNVPIGYALKDIPAGSWVHERLLDMPAARGLDNLPIATVKPEPLPPLEGYTFEGYRN 121 Query: 130 ADGSVGTRNLLAITTTVQCVAGVVEHAVKRIRAELLPKYPNVEDVVALEHTYGCGVAIDA 189 ADGSVG+RN+LAITTTVQCVAGVVE AVKRI+ ELLP++PNV+DVV LEH+YGCGVAIDA Sbjct: 122 ADGSVGSRNILAITTTVQCVAGVVEFAVKRIKDELLPRFPNVDDVVGLEHSYGCGVAIDA 181 Query: 190 PNAGIPIRTLRNISLNPNFGGQAMVVSLGCEKLQPNRLLPENMIPIHKQGE--------- 240 P+A IPIRTLRNI+LNPNFGG+ MVVSLGCEKLQP RLLP IPI + Sbjct: 182 PDAIIPIRTLRNITLNPNFGGEVMVVSLGCEKLQPERLLPPGTIPIMDERNVADVGVTAE 241 Query: 241 -PY-VVCLQDAEHVGFNSMIDSIMNMAEARLTELNKRRRETCPASDLVVGVQCGGSDAFS 298 P VVCLQ +HVGF SMIDSIM+ AE L L+ RRRET PAS+LVVGVQCGGSDAFS Sbjct: 242 APLDVVCLQSEQHVGFMSMIDSIMSAAELHLERLDARRRETVPASELVVGVQCGGSDAFS 301 Query: 299 GVTANPAVGFATDLLVRAGASVMFSEVTEVRDGIDQLTSRAVNEEVAQAMIREMDWYDNY 358 GVTANPAVGF TDLLVRAGA+VMFSE TEVRDGIDQLT+RA EVA+AMIREM WYD Y Sbjct: 302 GVTANPAVGFCTDLLVRAGATVMFSETTEVRDGIDQLTARATTPEVAEAMIREMAWYDAY 361 Query: 359 LKQGGVDRSANTTPGNKKGGLANIVEKAMGSIVKSGSSPISGVLSPGDKLQQ---KGLIY 415 L++G VDRSANTTPGNKKGGL+NIVEKAMGSIVKSGS+PISGVLSPG+K++Q KGL++ Sbjct: 362 LEKGRVDRSANTTPGNKKGGLSNIVEKAMGSIVKSGSAPISGVLSPGEKVRQKGLKGLVF 421 Query: 416 AATPASDFICGTLQLAAGMNLHIFTTGRGTPYGLAAVPVIKVATRNDLARRWHDLMDVNA 475 AATPASDFICGTLQLAAG+NLH+FTTGRGTPYGLA VPVIKVATR DLARRWHDLMD+NA Sbjct: 422 AATPASDFICGTLQLAAGINLHVFTTGRGTPYGLAEVPVIKVATRTDLARRWHDLMDINA 481 Query: 476 GRIASGEASIEDVGWELFQLMLDVASGKKRTWAEQWKLHNALTLFNPAPVT 526 GRIA G+A+IEDVG ELFQ MLDVASG+K+TWAE WKLHNAL LFNPAPVT Sbjct: 482 GRIADGDATIEDVGRELFQFMLDVASGRKKTWAEHWKLHNALVLFNPAPVT 532 >E6V7T9.1 E6V7T9_VARPD Galactarate dehydratase EC=4.2.1.42 Length = 525 Score = 834 bits (2154), Expect = 0.0, Method: Compositional matrix adjust. Identities = 409/517 (79%), Positives = 449/517 (86%), Gaps = 7/517 (1%) Query: 17 PRYIMMNDTDNVAIVVNDGGLPAGTVFPDGLTLVDRVPQGHKIALRDLKQGEVIVRYDVA 76 P YI ++ DNVAIV NDGGL G F DGL LVD VPQGHK+AL DL G+ IVRY+V Sbjct: 9 PLYIRIHAADNVAIVANDGGLKTGATFADGLVLVDNVPQGHKVALADLADGDAIVRYNVV 68 Query: 77 IGYAVRDIPKGSWIEESLVQMPPARELDNLPIATKKPAPQPPLEGYTFEGYRNADGSVGT 136 IGYA + +P+GSW+ E +++MP A ELD LPIAT KP PPLEGYTFEGYRNADGSVG+ Sbjct: 69 IGYAQKALPRGSWVHERVMRMPTAPELDGLPIATVKPPALPPLEGYTFEGYRNADGSVGS 128 Query: 137 RNLLAITTTVQCVAGVVEHAVKRIRAELLPKYPNVEDVVALEHTYGCGVAIDAPNAGIPI 196 RN+LAIT TVQCVAGV E AV+RI+AELLPK+PNV+DVVALEH+YGCGVAIDAP+A IPI Sbjct: 129 RNILAITQTVQCVAGVTEFAVQRIKAELLPKFPNVDDVVALEHSYGCGVAIDAPDAIIPI 188 Query: 197 RTLRNISLNPNFGGQAMVVSLGCEKLQPNRLLPENMIPIHKQ-GE-----PY-VVCLQDA 249 RTLRNISLNPNFGG+ MVVSLGCEKLQP RLLP IPI Q GE P VVCLQD Sbjct: 189 RTLRNISLNPNFGGEVMVVSLGCEKLQPERLLPPGTIPITDQRGEGATDAPLDVVCLQDD 248 Query: 250 EHVGFNSMIDSIMNMAEARLTELNKRRRETCPASDLVVGVQCGGSDAFSGVTANPAVGFA 309 HVGF SMIDS+M AE L LN RRRET PAS+LVVGVQCGGSDAFSGVTANPAVGFA Sbjct: 249 AHVGFMSMIDSVMRQAEVHLARLNTRRRETVPASELVVGVQCGGSDAFSGVTANPAVGFA 308 Query: 310 TDLLVRAGASVMFSEVTEVRDGIDQLTSRAVNEEVAQAMIREMDWYDNYLKQGGVDRSAN 369 TDLLVRAGA+VMFSE TEVRDGIDQLTSRA + EVA+AMIREM WYD YL++G VDRSAN Sbjct: 309 TDLLVRAGATVMFSETTEVRDGIDQLTSRASSPEVAEAMIREMAWYDAYLQKGRVDRSAN 368 Query: 370 TTPGNKKGGLANIVEKAMGSIVKSGSSPISGVLSPGDKLQQKGLIYAATPASDFICGTLQ 429 TTPGNKKGGL+NIVEKAMGSIVKSGS+PI+GVLSPG+K++QKGLIYAATPASDFICGTLQ Sbjct: 369 TTPGNKKGGLSNIVEKAMGSIVKSGSAPITGVLSPGEKVKQKGLIYAATPASDFICGTLQ 428 Query: 430 LAAGMNLHIFTTGRGTPYGLAAVPVIKVATRNDLARRWHDLMDVNAGRIASGEASIEDVG 489 LAAG+NLHIFTTGRGTPYGLA VPVIKVATR+DLARRWHDLMDVNAGRIA G+A+IEDVG Sbjct: 429 LAAGINLHIFTTGRGTPYGLAEVPVIKVATRSDLARRWHDLMDVNAGRIADGDATIEDVG 488 Query: 490 WELFQLMLDVASGKKRTWAEQWKLHNALTLFNPAPVT 526 WELF+LMLDVASGKK+TWAE WKLHNAL LFNPAPVT Sbjct: 489 WELFRLMLDVASGKKKTWAEHWKLHNALVLFNPAPVT 525 >B3R923.1 B3R923_CUPTR (D)-galactarate dehydrogenase EC=4.2.1.42 Length = 521 Score = 833 bits (2152), Expect = 0.0, Method: Compositional matrix adjust. Identities = 396/514 (77%), Positives = 449/514 (87%), Gaps = 2/514 (0%) Query: 13 QASAPRYIMMNDTDNVAIVVNDGGLPAGTVFPDGLTLVDRVPQGHKIALRDLKQGEVIVR 72 QAS P YI M+ DNVAIV NDGGLPAGT FP GL L + +PQGHK+AL DL++G+ ++R Sbjct: 10 QASRPLYIAMHAADNVAIVANDGGLPAGTAFPCGLVLKEAIPQGHKVALADLREGDAVIR 69 Query: 73 YDVAIGYAVRDIPKGSWIEESLVQMPPARELDNLPIATKKPAPQPPLEGYTFEGYRNADG 132 Y+V IGYA+RD+P+GSWI E +++MP A L+NLP++T+ AP PPLEGYTFEGYRNADG Sbjct: 70 YNVVIGYALRDLPRGSWINERVIRMPEAPGLENLPVSTRV-APLPPLEGYTFEGYRNADG 128 Query: 133 SVGTRNLLAITTTVQCVAGVVEHAVKRIRAELLPKYPNVEDVVALEHTYGCGVAIDAPNA 192 SVGTRN+L ITTTVQCV GVVE AV+RI+ ELLPKYPNV+DVV LEHTYGCGVAIDAP+A Sbjct: 129 SVGTRNILGITTTVQCVEGVVEFAVRRIKEELLPKYPNVDDVVGLEHTYGCGVAIDAPDA 188 Query: 193 GIPIRTLRNISLNPNFGGQAMVVSLGCEKLQPNRLLPENMIPIHKQGEPYVVCLQDAEHV 252 GIPIRT+RNI+LNPNFGG+ M+VSLGCEKLQP RL+ IPI K GEP VVCLQD +HV Sbjct: 189 GIPIRTIRNIALNPNFGGEVMIVSLGCEKLQPARLIGAGTIPIQKAGEPDVVCLQDEQHV 248 Query: 253 GFNSMIDSIMNMAEARLTELNKRRRETCPASDLVVGVQCGGSDAFSGVTANPAVGFATDL 312 GF +MIDSIM AE L LN RRRETCPASDLVVGVQCGGSDAFSGVTANPAVGFATDL Sbjct: 249 GFAAMIDSIMVTAEKHLARLNARRRETCPASDLVVGVQCGGSDAFSGVTANPAVGFATDL 308 Query: 313 LVRAGASVMFSEVTEVRDGIDQLTSRAVNEEVAQAMIREMDWYDNYLKQGGVDRSANTTP 372 LVRAGA+VMFSEVTEVRDGIDQLT+RA EVA+A++R+M WYD YL+QG VDRSANTTP Sbjct: 309 LVRAGATVMFSEVTEVRDGIDQLTARAATPEVAEALVRQMAWYDRYLEQGQVDRSANTTP 368 Query: 373 GNKKGGLANIVEKAMGSIVKSGSSPISGVLSPGDKLQQKGLIYAATPASDFICGTLQLAA 432 GNKKGGL+NIVEKAMGSIVKSG+ PI GV PG+K+ QKGLIYAATPA DF+CGTLQLAA Sbjct: 369 GNKKGGLSNIVEKAMGSIVKSGTGPIHGVSGPGEKVTQKGLIYAATPAGDFVCGTLQLAA 428 Query: 433 GMNLHIFTTGRGTPYGLAAVPVIKVATRNDLARRWHDLMDVNAGRIASGEASIEDVGWEL 492 GMNLH+FTTGRGTPYGLA VPV+KV+TRNDLARRWHDLMDVNAGRIA+GEA+IE+VGWEL Sbjct: 429 GMNLHVFTTGRGTPYGLAEVPVVKVSTRNDLARRWHDLMDVNAGRIATGEATIEEVGWEL 488 Query: 493 FQLMLDVASGKKRTWAEQWKLHNALTLFNPAPVT 526 F +L VASGKK +WAE WK+ NAL LFNPAPVT Sbjct: 489 FHTLLAVASGKK-SWAEHWKIRNALVLFNPAPVT 521 >Q128M4.1 Q128M4_POLSJ Galactarate dehydratase EC=4.2.1.42 Length = 548 Score = 831 bits (2147), Expect = 0.0, Method: Compositional matrix adjust. Identities = 403/522 (77%), Positives = 449/522 (86%), Gaps = 11/522 (2%) Query: 16 APRYIMMNDTDNVAIVVNDGGLPAGTVFPDGLTLVDRVPQGHKIALRDLKQGEVIVRYDV 75 AP YI M+D DNVAIV NDGGLPAGTVF GL L ++VPQGHK+AL DL +G ++RY+V Sbjct: 27 APLYITMHDHDNVAIVANDGGLPAGTVFDSGLRLCEQVPQGHKVALVDLPKGTAVLRYNV 86 Query: 76 AIGYAVRDIPKGSWIEESLVQMPPARELDNLPIATKKPAPQPPLEGYTFEGYRNADGSVG 135 IGYA++DIP GSW+ E L++MP ARELDNLPIAT +P PPLEGYTFEGYRN DGSVG Sbjct: 87 PIGYALKDIPAGSWVHERLLEMPSARELDNLPIATVRPPVLPPLEGYTFEGYRNPDGSVG 146 Query: 136 TRNLLAITTTVQCVAGVVEHAVKRIRAELLPKYPNVEDVVALEHTYGCGVAIDAPNAGIP 195 +RN+LAITTTVQCVAGVVE AVKRI+ ELLP++PNV+DVV LEHTYGCGVAIDAP+A IP Sbjct: 147 SRNILAITTTVQCVAGVVEFAVKRIKDELLPRFPNVDDVVGLEHTYGCGVAIDAPDAIIP 206 Query: 196 IRTLRNISLNPNFGGQAMVVSLGCEKLQPNRLLPENMIPI-----------HKQGEPYVV 244 IRTLRNI+LNPNFGG+ MVVSLGCEKLQP RLLP I I + E VV Sbjct: 207 IRTLRNITLNPNFGGEVMVVSLGCEKLQPERLLPPGTIQIVDERNVADVGISAEAELDVV 266 Query: 245 CLQDAEHVGFNSMIDSIMNMAEARLTELNKRRRETCPASDLVVGVQCGGSDAFSGVTANP 304 CLQ HVGF SMIDSIM A L L+ RRRET PAS+LVVGVQCGGSDAFSGVTANP Sbjct: 267 CLQSEHHVGFMSMIDSIMETALLHLERLDARRRETVPASELVVGVQCGGSDAFSGVTANP 326 Query: 305 AVGFATDLLVRAGASVMFSEVTEVRDGIDQLTSRAVNEEVAQAMIREMDWYDNYLKQGGV 364 AVGFATDLLVRAGA+VMFSE TEVRDGIDQLTSRA EVA+AMIREM WYD YL++G V Sbjct: 327 AVGFATDLLVRAGATVMFSETTEVRDGIDQLTSRASTPEVAEAMIREMAWYDAYLQKGRV 386 Query: 365 DRSANTTPGNKKGGLANIVEKAMGSIVKSGSSPISGVLSPGDKLQQKGLIYAATPASDFI 424 DRSANTTPGNKKGGL+NIVEKAMGSIVKSG++PISGVLSPG+K++QKGLIYAATPASDFI Sbjct: 387 DRSANTTPGNKKGGLSNIVEKAMGSIVKSGTAPISGVLSPGEKVRQKGLIYAATPASDFI 446 Query: 425 CGTLQLAAGMNLHIFTTGRGTPYGLAAVPVIKVATRNDLARRWHDLMDVNAGRIASGEAS 484 CGTLQLAAGMNLH+FTTGRGTPYGLA VPVIKVATR+DLARRWHDLMDVNAGRIA G+A+ Sbjct: 447 CGTLQLAAGMNLHVFTTGRGTPYGLAEVPVIKVATRSDLARRWHDLMDVNAGRIADGDAT 506 Query: 485 IEDVGWELFQLMLDVASGKKRTWAEQWKLHNALTLFNPAPVT 526 IE++GWELF LML+VASG+K+TWAE WKLHNAL LFNPAP+T Sbjct: 507 IEELGWELFHLMLEVASGRKKTWAEHWKLHNALVLFNPAPIT 548 >Q0K2L8.1 Q0K2L8_CUPNH Probable D-galactarate dehydratase EC=4.2.1.42 Length = 521 Score = 829 bits (2142), Expect = 0.0, Method: Compositional matrix adjust. Identities = 395/520 (75%), Positives = 450/520 (86%), Gaps = 2/520 (0%) Query: 7 TDTSASQASAPRYIMMNDTDNVAIVVNDGGLPAGTVFPDGLTLVDRVPQGHKIALRDLKQ 66 T T+ QA+ P YI M+ DNVAIV NDGGLPAG FP GL L + VPQGHK+AL DL++ Sbjct: 4 TPTAGGQAARPLYITMHANDNVAIVANDGGLPAGMEFPCGLVLAEGVPQGHKVALTDLRE 63 Query: 67 GEVIVRYDVAIGYAVRDIPKGSWIEESLVQMPPARELDNLPIATKKPAPQPPLEGYTFEG 126 G+ ++RY+V IGYA++D+P+GSW+ E +++MP A EL +LP+ T+ AP PLEGYTFEG Sbjct: 64 GDAVIRYNVVIGYALKDLPRGSWVNERVIRMPAAPELHDLPVGTRV-APLLPLEGYTFEG 122 Query: 127 YRNADGSVGTRNLLAITTTVQCVAGVVEHAVKRIRAELLPKYPNVEDVVALEHTYGCGVA 186 YRNADGSVGTRN+L ITTTVQCV GVVE AV+RI+ ELLPKYPNV+DVV LEHTYGCGVA Sbjct: 123 YRNADGSVGTRNILGITTTVQCVEGVVEFAVRRIKEELLPKYPNVDDVVGLEHTYGCGVA 182 Query: 187 IDAPNAGIPIRTLRNISLNPNFGGQAMVVSLGCEKLQPNRLLPENMIPIHKQGEPYVVCL 246 IDAP+AGIPIRT+RNI+LNPNFGG+ M+VSLGCEKLQP RL+ IPI ++GEP VVCL Sbjct: 183 IDAPDAGIPIRTIRNIALNPNFGGEVMIVSLGCEKLQPARLIGAGTIPIQQEGEPDVVCL 242 Query: 247 QDAEHVGFNSMIDSIMNMAEARLTELNKRRRETCPASDLVVGVQCGGSDAFSGVTANPAV 306 QD +HVGF SMIDSIM AE L LN RRRETCPASDLVVGVQCGGSDAFSGVTANPAV Sbjct: 243 QDEQHVGFASMIDSIMATAEKHLARLNARRRETCPASDLVVGVQCGGSDAFSGVTANPAV 302 Query: 307 GFATDLLVRAGASVMFSEVTEVRDGIDQLTSRAVNEEVAQAMIREMDWYDNYLKQGGVDR 366 GFATDLLVRAGA+VMFSEVTEVRDGIDQLT+RA EVA+A++R+M WYD YL+QG VDR Sbjct: 303 GFATDLLVRAGATVMFSEVTEVRDGIDQLTARAATPEVAEALVRQMAWYDRYLEQGKVDR 362 Query: 367 SANTTPGNKKGGLANIVEKAMGSIVKSGSSPISGVLSPGDKLQQKGLIYAATPASDFICG 426 SANTTPGNKKGGL+NIVEKAMGSIVKSG+ PI GV PG+K+ QKGLIYAATPA DF+CG Sbjct: 363 SANTTPGNKKGGLSNIVEKAMGSIVKSGTGPIHGVTGPGEKVTQKGLIYAATPAGDFVCG 422 Query: 427 TLQLAAGMNLHIFTTGRGTPYGLAAVPVIKVATRNDLARRWHDLMDVNAGRIASGEASIE 486 TLQLAAGMNLH+FTTGRGTPYGLA VPVIKV+TRNDLARRWHDLMDVNAGRIA+GEA+IE Sbjct: 423 TLQLAAGMNLHVFTTGRGTPYGLAEVPVIKVSTRNDLARRWHDLMDVNAGRIATGEATIE 482 Query: 487 DVGWELFQLMLDVASGKKRTWAEQWKLHNALTLFNPAPVT 526 +VGWELF +L VASGKK +WAE WK+ NAL LFNPAPVT Sbjct: 483 EVGWELFHTLLAVASGKK-SWAEHWKIRNALVLFNPAPVT 521 >C5CU21.1 C5CU21_VARPS Galactarate dehydratase EC=4.2.1.42 Length = 529 Score = 829 bits (2142), Expect = 0.0, Method: Compositional matrix adjust. Identities = 403/522 (77%), Positives = 448/522 (85%), Gaps = 11/522 (2%) Query: 16 APRYIMMNDTDNVAIVVNDGGLPAGTVFPDGLTLVDRVPQGHKIALRDLKQGEVIVRYDV 75 AP +I M+ DNVAIV NDGGLPAGTV GL LVD+VPQ HK+AL D+ +G V+ RY+V Sbjct: 8 APHFIRMHAADNVAIVANDGGLPAGTVLASGLVLVDKVPQAHKVALEDIPEGGVVRRYNV 67 Query: 76 AIGYAVRDIPKGSWIEESLVQMPPARELDNLPIATKKPAPQPPLEGYTFEGYRNADGSVG 135 IGYA++ IP GSW+ E L+QMP AREL+ LPIAT +P QPPLEGYTFEGYRN DGSVG Sbjct: 68 PIGYALKPIPAGSWVHERLLQMPAARELEGLPIATVRPPAQPPLEGYTFEGYRNLDGSVG 127 Query: 136 TRNLLAITTTVQCVAGVVEHAVKRIRAELLPKYPNVEDVVALEHTYGCGVAIDAPNAGIP 195 TRN+LAIT TVQCVAGVV+ AV+RI+AELLPKYPNV+DVV L H+YGCGVAIDAP+A IP Sbjct: 128 TRNILAITQTVQCVAGVVDFAVQRIKAELLPKYPNVDDVVGLSHSYGCGVAIDAPDAVIP 187 Query: 196 IRTLRNISLNPNFGGQAMVVSLGCEKLQPNRLLPENMIPIHKQ------GEPY-----VV 244 IRTLRNISLNPNFGG+ MV+SLGCEKLQP RLLP I + + GE VV Sbjct: 188 IRTLRNISLNPNFGGEVMVISLGCEKLQPERLLPPGSIALVDERNVADVGETANAKLDVV 247 Query: 245 CLQDAEHVGFNSMIDSIMNMAEARLTELNKRRRETCPASDLVVGVQCGGSDAFSGVTANP 304 CLQD HVGF SMIDSIM AE L LN RRRET PAS+LVVGVQCGGSDAFSGVTANP Sbjct: 248 CLQDDAHVGFMSMIDSIMRQAEEHLERLNARRRETVPASELVVGVQCGGSDAFSGVTANP 307 Query: 305 AVGFATDLLVRAGASVMFSEVTEVRDGIDQLTSRAVNEEVAQAMIREMDWYDNYLKQGGV 364 AVGF TDLLVRAGA+VMFSEVTEVRDGIDQLTSRA EVA+AMIREM WYD YL +G V Sbjct: 308 AVGFCTDLLVRAGATVMFSEVTEVRDGIDQLTSRATTPEVAEAMIREMAWYDAYLDRGRV 367 Query: 365 DRSANTTPGNKKGGLANIVEKAMGSIVKSGSSPISGVLSPGDKLQQKGLIYAATPASDFI 424 DRSANTTPGNKKGGL+NIVEKAMGSIVKSGS+PISGV++PG+K +QKGL+YAATPASDFI Sbjct: 368 DRSANTTPGNKKGGLSNIVEKAMGSIVKSGSAPISGVVAPGEKAKQKGLLYAATPASDFI 427 Query: 425 CGTLQLAAGMNLHIFTTGRGTPYGLAAVPVIKVATRNDLARRWHDLMDVNAGRIASGEAS 484 CGTLQLAAGMNLH+FTTGRGTPYGLA VPVIKVATR+DLARRWHDLMDVNAGRIA G+A+ Sbjct: 428 CGTLQLAAGMNLHVFTTGRGTPYGLAEVPVIKVATRSDLARRWHDLMDVNAGRIADGDAT 487 Query: 485 IEDVGWELFQLMLDVASGKKRTWAEQWKLHNALTLFNPAPVT 526 IED+GWE+F+LMLDVASG+K+TWAEQWKLHNAL LFNPAPVT Sbjct: 488 IEDIGWEMFRLMLDVASGRKKTWAEQWKLHNALVLFNPAPVT 529 >A2WGM0.1 A2WGM0_9BURK Altronate dehydratase Length = 517 Score = 817 bits (2111), Expect = 0.0, Method: Compositional matrix adjust. Identities = 402/515 (78%), Positives = 454/515 (88%), Gaps = 3/515 (0%) Query: 15 SAPRYIMMNDTDNVAIVVNDGGLPAGTVFPDGLTLVDRVPQGHKIALRDLKQGEVIVRYD 74 ++P YI ++ DNVAIVVNDGGLP G F DGLTL + VPQGHK+AL DL G+ IVRY+ Sbjct: 3 ASPLYIRVHPDDNVAIVVNDGGLPEGATFADGLTLREGVPQGHKVALVDLAAGDPIVRYN 62 Query: 75 VAIGYAVRDIPKGSWIEESLVQMPPARELDNLPIATKKPAPQPPLEGYTFEGYRNADGSV 134 V IGYA+ D+ +GSW+ E ++MP LDNLP+AT++ P PPLEGYTFEG+RN DGSV Sbjct: 63 VVIGYALTDLRRGSWVNERTMRMPEPPGLDNLPLATRRAPPLPPLEGYTFEGFRNPDGSV 122 Query: 135 GTRNLLAITTTVQCVAGVVEHAVKRIRAELLPKYPNVEDVVALEHTYGCGVAIDAPNAGI 194 GTRN+LAITTTVQCV+GVVEHAVKRI+AELLP+YPNV+DVV LEHTYGCGVAIDAP+A I Sbjct: 123 GTRNILAITTTVQCVSGVVEHAVKRIKAELLPRYPNVDDVVGLEHTYGCGVAIDAPDADI 182 Query: 195 PIRTLRNISLNPNFGGQAMVVSLGCEKLQPNRLLPENMIPIHKQGEPY---VVCLQDAEH 251 PIRTLRNISLNPNFGG+ M VSLGCEKLQP RLLP IP+ G VVCLQDA H Sbjct: 183 PIRTLRNISLNPNFGGEVMTVSLGCEKLQPERLLPPGAIPVAADGATDNGGVVCLQDAAH 242 Query: 252 VGFNSMIDSIMNMAEARLTELNKRRRETCPASDLVVGVQCGGSDAFSGVTANPAVGFATD 311 VGFNSMIDSIM MAE L LN+RRRETCPASDLVVGVQCGGSDAFSG+TANPAVGFA D Sbjct: 243 VGFNSMIDSIMKMAELHLERLNRRRRETCPASDLVVGVQCGGSDAFSGLTANPAVGFAAD 302 Query: 312 LLVRAGASVMFSEVTEVRDGIDQLTSRAVNEEVAQAMIREMDWYDNYLKQGGVDRSANTT 371 LLVRAGA++MFSEVTEVRDG+ QLTSRAVNE+VA+ +IREMDWYD YL++G VDRSANTT Sbjct: 303 LLVRAGATIMFSEVTEVRDGVAQLTSRAVNEDVAREIIREMDWYDRYLQRGRVDRSANTT 362 Query: 372 PGNKKGGLANIVEKAMGSIVKSGSSPISGVLSPGDKLQQKGLIYAATPASDFICGTLQLA 431 PGNKKGGL+NIVEKAMGSIVKSGS+PI+GV+ PG++ +QKGL+YAATPASDFICGTLQLA Sbjct: 363 PGNKKGGLSNIVEKAMGSIVKSGSAPIAGVVRPGERARQKGLLYAATPASDFICGTLQLA 422 Query: 432 AGMNLHIFTTGRGTPYGLAAVPVIKVATRNDLARRWHDLMDVNAGRIASGEASIEDVGWE 491 AGMNLH+FTTGRGTPYGLA VPVIKVATR+DLARRWHDLMDV+AG+IA+G A+IEDVGWE Sbjct: 423 AGMNLHVFTTGRGTPYGLAQVPVIKVATRSDLARRWHDLMDVDAGQIATGAATIEDVGWE 482 Query: 492 LFQLMLDVASGKKRTWAEQWKLHNALTLFNPAPVT 526 LF+LMLDVASGK+RTWAEQWKL NALTLFNPAPVT Sbjct: 483 LFRLMLDVASGKRRTWAEQWKLANALTLFNPAPVT 517