BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0013.p (297 letters) Database: pfamseq 15,929,002 sequences; 5,169,768,107 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D8J0J8.1 D8J0J8_HERSS 3-hydroxyisobutyrate dehydrogenase protein... 597 e-169 Q2L112.1 Q2L112_BORA1 3-hydroxyisobutyrate dehydrogenase EC=1.1.... 351 1e-94 B8LA10.1 B8LA10_9GAMM 3-hydroxyisobutyrate dehydrogenase EC=1.1.... 349 3e-94 B2FI84.1 B2FI84_STRMK Putative 3-hydroxyisobutyrate dehydrogenas... 348 7e-94 B4SSP6.1 B4SSP6_STRM5 3-hydroxyisobutyrate dehydrogenase EC=1.1.... 347 1e-93 A9INM6.1 A9INM6_BORPD 3-hydroxyisobutyrate dehydrogenase EC=1.1.... 347 1e-93 E4PEW9.1 E4PEW9_MARAH 3-hydroxyisobutyrate dehydrogenase EC=1.1.... 343 3e-92 D4XC62.1 D4XC62_9BURK 3-hydroxyisobutyrate dehydrogenase EC=1.1.1.- 339 3e-91 E3HTN6.1 E3HTN6_ACHXA 3-hydroxyisobutyrate dehydrogenase 1 EC=1.... 338 4e-91 Q8EGC2.1 Q8EGC2_SHEON 3-hydroxyisobutyrate dehydrogenase 338 7e-91 >D8J0J8.1 D8J0J8_HERSS 3-hydroxyisobutyrate dehydrogenase protein EC=1.1.1.31 Length = 297 Score = 597 bits (1540), Expect = e-169, Method: Compositional matrix adjust. Identities = 296/297 (99%), Positives = 297/297 (100%) Query: 1 MSANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKAD 60 MSANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKAD Sbjct: 1 MSANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKAD 60 Query: 61 VVITMLPASRHVESLYLGEAGVLASAKPGTLLIDCSTIAPEAARKVAAAAKARGFEMLDA 120 VVITMLPASRHVESLYLGEAGVLASAKPGTLLIDCSTIAPEAARKVAAAAKARGFEMLDA Sbjct: 61 VVITMLPASRHVESLYLGEAGVLASAKPGTLLIDCSTIAPEAARKVAAAAKARGFEMLDA 120 Query: 121 PVSGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLG 180 PVSGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLG Sbjct: 121 PVSGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLG 180 Query: 181 ILMIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMDTAPASKGYAGGF 240 ILMIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVM+TAPASKGYAGGF Sbjct: 181 ILMIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMETAPASKGYAGGF 240 Query: 241 GVDLMLKDLGLAVENALATNCAIPLGATARNLYDIHSMNGAGKLDFSSIFNMLGKAQ 297 GVDLMLKDLGLAVENALATNCAIPLGATARNLYDIHSMNGAGKLDFSSIFNMLGKAQ Sbjct: 241 GVDLMLKDLGLAVENALATNCAIPLGATARNLYDIHSMNGAGKLDFSSIFNMLGKAQ 297 >Q2L112.1 Q2L112_BORA1 3-hydroxyisobutyrate dehydrogenase EC=1.1.1.31 Length = 294 Score = 351 bits (900), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 195/290 (67%), Positives = 230/290 (79%), Gaps = 3/290 (1%) Query: 3 ANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKADVV 62 ++I FIGLGNMG PMA NLVKAG S+ DL+ +V +L E G + + AAV AD+V Sbjct: 2 SSIAFIGLGNMGAPMALNLVKAGHSLVVFDLLADAVQRLTEAGARAATSASAAVDGADIV 61 Query: 63 ITMLPASRHVESLYLGEAGVLASAKPGTLLIDCSTIAPEAARKVAAAAKARGFEMLDAPV 122 ITMLPAS+HVE LYL E +L K G L+IDCSTIAP++ARKVAAAA ARG EM+DAPV Sbjct: 62 ITMLPASKHVEHLYL-EQDLLGKIKAGALVIDCSTIAPDSARKVAAAATARGLEMIDAPV 120 Query: 123 SGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLGIL 182 SGGT GA AGTLTF+VGG+ A E A+P L+KMGK I+HAGE+GSGQ K+CNNMLLGIL Sbjct: 121 SGGTGGAVAGTLTFIVGGA--ALERARPVLEKMGKNIFHAGEAGSGQVAKICNNMLLGIL 178 Query: 183 MIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMDTAPASKGYAGGFGV 242 M GTSEA+ LG+ANG+DPKVLS+I++KSSGRNW E+YNP PGVM APAS GYAGGFGV Sbjct: 179 MAGTSEALALGVANGLDPKVLSDIIAKSSGRNWATELYNPWPGVMPHAPASHGYAGGFGV 238 Query: 243 DLMLKDLGLAVENALATNCAIPLGATARNLYDIHSMNGAGKLDFSSIFNM 292 DLMLKDLGLA E AL + +IPLG ARNLY +HS G+G+LDFSSI N+ Sbjct: 239 DLMLKDLGLAAEAALGSRSSIPLGELARNLYSLHSNGGSGRLDFSSIVNL 288 >B8LA10.1 B8LA10_9GAMM 3-hydroxyisobutyrate dehydrogenase EC=1.1.1.31 Length = 296 Score = 349 bits (895), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 174/291 (59%), Positives = 221/291 (75%) Query: 3 ANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKADVV 62 + I FIGLGNMG PMA NLVK G SV DLV A+V V+ G + + +A A+VV Sbjct: 2 SRIAFIGLGNMGGPMAANLVKNGHSVRVFDLVPAAVQAAVDAGASAASTARDTLADAEVV 61 Query: 63 ITMLPASRHVESLYLGEAGVLASAKPGTLLIDCSTIAPEAARKVAAAAKARGFEMLDAPV 122 I+MLPASRHVE +YLG+ G+LA+ G L+IDCSTIAP +ARKV+ AA ARG +M+DAPV Sbjct: 62 ISMLPASRHVEGVYLGDDGILAAIPAGALVIDCSTIAPASARKVSEAAAARGLQMIDAPV 121 Query: 123 SGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLGIL 182 SGGT GA AGTLTF+VGG ++A E A+P LQ MGK I+H G SG+GQ K+CNNM LG++ Sbjct: 122 SGGTAGAQAGTLTFIVGGEEDALERARPVLQAMGKNIFHVGASGAGQVAKLCNNMALGVI 181 Query: 183 MIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMDTAPASKGYAGGFGV 242 M T EAI LG+A+G+DPKVLS++M+ S+GR+W EV NP PGV++ APAS+GY+GGFG Sbjct: 182 MAVTGEAIALGVAHGLDPKVLSQMMAVSTGRSWATEVCNPWPGVLENAPASRGYSGGFGS 241 Query: 243 DLMLKDLGLAVENALATNCAIPLGATARNLYDIHSMNGAGKLDFSSIFNML 293 DLMLKD+GLAVE A++ +IPLG ARNLY ++ G GKLDFSS+ ++ Sbjct: 242 DLMLKDMGLAVEAAMSVGASIPLGEVARNLYSMNHQAGRGKLDFSSVVQLI 292 >B2FI84.1 B2FI84_STRMK Putative 3-hydroxyisobutyrate dehydrogenase EC=1.1.1.31 Length = 296 Score = 348 bits (892), Expect = 7e-94, Method: Compositional matrix adjust. Identities = 174/291 (59%), Positives = 221/291 (75%) Query: 3 ANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKADVV 62 + I FIGLGNMG PMA NLVK G SV DLV A+V V+ G + + +A A+VV Sbjct: 2 SRIAFIGLGNMGGPMAANLVKNGHSVRVFDLVPAAVQAAVDAGASAASSARDTLADAEVV 61 Query: 63 ITMLPASRHVESLYLGEAGVLASAKPGTLLIDCSTIAPEAARKVAAAAKARGFEMLDAPV 122 I+MLPASRHVE +YLG+ G+LA+ G L+IDCSTIAP +ARKV+ AA ARG +M+DAPV Sbjct: 62 ISMLPASRHVEGVYLGDDGILAAIPAGALVIDCSTIAPASARKVSEAAAARGLQMIDAPV 121 Query: 123 SGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLGIL 182 SGGT GA AGTLTF+VGG ++A E A+P LQ MGK I+H G SG+GQ K+CNNM LG++ Sbjct: 122 SGGTAGAQAGTLTFIVGGEEDALERARPVLQAMGKNIFHVGASGAGQVAKLCNNMALGVI 181 Query: 183 MIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMDTAPASKGYAGGFGV 242 M T EAI LG+A+G+DPKVLS++M+ S+GR+W EV NP PGV++ APAS+GY+GGFG Sbjct: 182 MAVTGEAIALGVAHGLDPKVLSQMMAVSTGRSWATEVCNPWPGVLENAPASRGYSGGFGS 241 Query: 243 DLMLKDLGLAVENALATNCAIPLGATARNLYDIHSMNGAGKLDFSSIFNML 293 DLMLKD+GLAVE A++ +IPLG ARNLY ++ G GKLDFSS+ ++ Sbjct: 242 DLMLKDMGLAVEAAMSVGASIPLGEVARNLYSMNHQAGRGKLDFSSVVQLI 292 >B4SSP6.1 B4SSP6_STRM5 3-hydroxyisobutyrate dehydrogenase EC=1.1.1.31 Length = 296 Score = 347 bits (891), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 174/291 (59%), Positives = 221/291 (75%) Query: 3 ANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKADVV 62 + I FIGLGNMG PMA NLVK G +V DLV A+V V+ G A + +A A+VV Sbjct: 2 SRIAFIGLGNMGGPMAANLVKNGHTVRVFDLVPAAVQAAVDAGASAAASARETLADAEVV 61 Query: 63 ITMLPASRHVESLYLGEAGVLASAKPGTLLIDCSTIAPEAARKVAAAAKARGFEMLDAPV 122 I+MLPASRHVE +YLG+ G+LA+ G L+IDCSTIAP +ARKV+ AA ARG +M+DAPV Sbjct: 62 ISMLPASRHVEGVYLGDDGILAAIPAGALVIDCSTIAPASARKVSEAAAARGLQMIDAPV 121 Query: 123 SGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLGIL 182 SGGT GA AGTLTF+VGG ++A E A+P LQ MGK I+H G SG+GQ K+CNNM LG++ Sbjct: 122 SGGTAGAQAGTLTFIVGGEEDALERARPVLQAMGKNIFHVGASGAGQVAKLCNNMALGVI 181 Query: 183 MIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMDTAPASKGYAGGFGV 242 M T EAI LG+A+G+DPKVLS++M+ S+GR+W EV NP PGV++ APAS+GY+GGFG Sbjct: 182 MAVTGEAIALGVAHGLDPKVLSQMMAVSTGRSWATEVCNPWPGVLENAPASRGYSGGFGS 241 Query: 243 DLMLKDLGLAVENALATNCAIPLGATARNLYDIHSMNGAGKLDFSSIFNML 293 DLMLKD+GLAVE A++ +IPLG ARNLY ++ G GKLDFSS+ ++ Sbjct: 242 DLMLKDMGLAVEAAMSVGASIPLGEVARNLYSMNHQAGRGKLDFSSVVQLI 292 >A9INM6.1 A9INM6_BORPD 3-hydroxyisobutyrate dehydrogenase EC=1.1.1.31 Length = 295 Score = 347 bits (890), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 189/290 (65%), Positives = 233/290 (80%), Gaps = 1/290 (0%) Query: 3 ANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKADVV 62 ++I FIGLGNMG PMA NL+KAG S++ DLV A+V L + G + + AV A+VV Sbjct: 2 SSIAFIGLGNMGAPMAHNLIKAGHSLTVFDLVPAAVQGLSDAGARAAGSAAEAVRGAEVV 61 Query: 63 ITMLPASRHVESLYLGEAGVLASAKPGTLLIDCSTIAPEAARKVAAAAKARGFEMLDAPV 122 I+MLPAS+HVE+LYL + +L+S P L+I+CSTIAP++ARKVAAAA+ARG M+DAPV Sbjct: 62 ISMLPASKHVEALYL-DNDLLSSIDPSALVIECSTIAPDSARKVAAAAQARGLAMIDAPV 120 Query: 123 SGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLGIL 182 SGGT GA AGTLTF+VGG +A + A P LQ MGK I+HAG +G+GQ K+CNNMLLGIL Sbjct: 121 SGGTGGAAAGTLTFIVGGEPDALQRAMPVLQNMGKNIFHAGTAGAGQVAKICNNMLLGIL 180 Query: 183 MIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMDTAPASKGYAGGFGV 242 M GTSEA+ LG+ANG+DPKVLS+I++KSSGRNW E+YNP PGVM+ APASKGYAGGFGV Sbjct: 181 MAGTSEALALGVANGLDPKVLSDIIAKSSGRNWATELYNPWPGVMEHAPASKGYAGGFGV 240 Query: 243 DLMLKDLGLAVENALATNCAIPLGATARNLYDIHSMNGAGKLDFSSIFNM 292 DLMLKDLGLA E+AL++ +IPLG ARNLY +HS G+GKLDFSSI N+ Sbjct: 241 DLMLKDLGLAAESALSSRSSIPLGELARNLYSLHSTGGSGKLDFSSIVNL 290 >E4PEW9.1 E4PEW9_MARAH 3-hydroxyisobutyrate dehydrogenase EC=1.1.1.31 Length = 295 Score = 343 bits (879), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 175/287 (60%), Positives = 209/287 (72%) Query: 3 ANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKADVV 62 A I FIGLGNMG PMA NLVKAG V+ DL K +V LV G KT + A + A+ V Sbjct: 2 AKITFIGLGNMGGPMAGNLVKAGHEVTVFDLSKDAVAALVSEGAKTAGTAHEAASGAECV 61 Query: 63 ITMLPASRHVESLYLGEAGVLASAKPGTLLIDCSTIAPEAARKVAAAAKARGFEMLDAPV 122 ITMLPA +HVE++YLG+ G+LA GTL+ID STIAPE AR VA A+A+ LDAPV Sbjct: 62 ITMLPAGQHVEAVYLGDDGLLAKLPAGTLVIDSSTIAPETARGVAEVARAKDIPFLDAPV 121 Query: 123 SGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLGIL 182 SGG GA AGTLTF+ GGS+EAF A+P L MGK I+HAG+ GSGQ K+CNNMLL IL Sbjct: 122 SGGVGGAKAGTLTFICGGSEEAFNKAKPILDTMGKNIFHAGDHGSGQVAKICNNMLLAIL 181 Query: 183 MIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMDTAPASKGYAGGFGV 242 M GTSEA+ LG+ NG+DP VLSEIM +SSG NW L VYNP PGVM+ PAS+ Y GGF V Sbjct: 182 MSGTSEALALGVKNGLDPAVLSEIMKQSSGGNWALNVYNPWPGVMEGVPASRNYEGGFLV 241 Query: 243 DLMLKDLGLAVENALATNCAIPLGATARNLYDIHSMNGAGKLDFSSI 289 +LM KDLGLA +NA+ +IP+G+ ARNL+ +H+ G G LDFSSI Sbjct: 242 NLMTKDLGLAFDNAVKNQASIPMGSLARNLFQLHAGQGNGSLDFSSI 288 >D4XC62.1 D4XC62_9BURK 3-hydroxyisobutyrate dehydrogenase EC=1.1.1.- Length = 296 Score = 339 bits (869), Expect = 3e-91, Method: Compositional matrix adjust. Identities = 190/295 (64%), Positives = 230/295 (77%), Gaps = 1/295 (0%) Query: 3 ANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKADVV 62 ++I FIGLGNMG PMA NLVKAG S++ DLV A+V L + G + A + AV ADVV Sbjct: 2 SSIAFIGLGNMGAPMALNLVKAGHSLTVFDLVPAAVKLLTDAGARAAASAAEAVKGADVV 61 Query: 63 ITMLPASRHVESLYLGEAGVLASAKPGTLLIDCSTIAPEAARKVAAAAKARGFEMLDAPV 122 ++MLPAS+HVE LYL + +L L+I+CSTIAP++ARKVA AA+ RG M+DAPV Sbjct: 62 VSMLPASKHVEGLYL-DQDLLGHISSSALVIECSTIAPDSARKVAQAAEVRGIAMIDAPV 120 Query: 123 SGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLGIL 182 SGGT GA AGTLTF+VGG A E A+P L+KMGK I+HAG +G+GQ K+CNNMLLGIL Sbjct: 121 SGGTGGAAAGTLTFIVGGQAAALERARPVLEKMGKNIFHAGPAGAGQVAKICNNMLLGIL 180 Query: 183 MIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMDTAPASKGYAGGFGV 242 M GTSEA+ LG+ANG+DPKVLS+I++KSSGRNW E+YNP PGVMD APASKGYAGGFGV Sbjct: 181 MAGTSEALALGVANGLDPKVLSDIIAKSSGRNWATELYNPWPGVMDHAPASKGYAGGFGV 240 Query: 243 DLMLKDLGLAVENALATNCAIPLGATARNLYDIHSMNGAGKLDFSSIFNMLGKAQ 297 DLMLKDLGLA E AL+ +IPLG ARNLY +HS G+GKLDFSSI N++ + Q Sbjct: 241 DLMLKDLGLAAEAALSARASIPLGELARNLYSLHSAGGSGKLDFSSIVNLVKREQ 295 >E3HTN6.1 E3HTN6_ACHXA 3-hydroxyisobutyrate dehydrogenase 1 EC=1.1.1.31 Length = 296 Score = 338 bits (868), Expect = 4e-91, Method: Compositional matrix adjust. Identities = 191/295 (64%), Positives = 231/295 (78%), Gaps = 1/295 (0%) Query: 3 ANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKADVV 62 ++I FIGLGNMG PMA NLVKAG SV+ DL+ A+V L + G K A + AV A+VV Sbjct: 2 SSIAFIGLGNMGAPMALNLVKAGHSVTVFDLMPAAVKILTDAGAKAAASASEAVKGAEVV 61 Query: 63 ITMLPASRHVESLYLGEAGVLASAKPGTLLIDCSTIAPEAARKVAAAAKARGFEMLDAPV 122 ++MLPAS+HVE LYLGE +L L+I+CSTIAP++ARKVA AA+ RG M+DAPV Sbjct: 62 VSMLPASKHVEGLYLGE-DLLGKIPSSALVIECSTIAPDSARKVAQAAEVRGIAMIDAPV 120 Query: 123 SGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLGIL 182 SGGT GA AGTLTF+VGG A E A+P L+KMGK I+HAG +G+GQ K+CNNMLLGIL Sbjct: 121 SGGTGGAAAGTLTFIVGGQAAALERARPVLEKMGKNIFHAGPAGAGQVAKICNNMLLGIL 180 Query: 183 MIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMDTAPASKGYAGGFGV 242 M GTSEA+ LG+ANG+DPKVLS+I++KSSGRNW E+YNP PGVM+ APASKGYAGGFGV Sbjct: 181 MAGTSEALALGVANGLDPKVLSDIIAKSSGRNWATELYNPWPGVMEHAPASKGYAGGFGV 240 Query: 243 DLMLKDLGLAVENALATNCAIPLGATARNLYDIHSMNGAGKLDFSSIFNMLGKAQ 297 DLMLKDLGLA E AL+ +IPLG ARNLY +HS G+GKLDFSSI N++ + Q Sbjct: 241 DLMLKDLGLAAEAALSARASIPLGELARNLYSLHSSGGSGKLDFSSIVNLVKREQ 295 >Q8EGC2.1 Q8EGC2_SHEON 3-hydroxyisobutyrate dehydrogenase Length = 300 Score = 338 bits (866), Expect = 7e-91, Method: Compositional matrix adjust. Identities = 171/294 (58%), Positives = 210/294 (71%), Gaps = 3/294 (1%) Query: 3 ANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKADVV 62 + + FIGLGNMG PMA NL+KAG +V DLV ++ L E G + + A A A+VV Sbjct: 2 STVAFIGLGNMGGPMAANLLKAGMTVRVFDLVHTAMQTLAEQGALVSSTACGAAAGANVV 61 Query: 63 ITMLPASRHVESLYLG---EAGVLASAKPGTLLIDCSTIAPEAARKVAAAAKARGFEMLD 119 ITMLPA +HV++LYLG E G+L TLLIDCSTI ++A+ VA A G E +D Sbjct: 62 ITMLPAGKHVKNLYLGSGSEKGLLDVVASDTLLIDCSTIDAQSAQLVATQAAKNGLEFMD 121 Query: 120 APVSGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLL 179 APVSGGT+GA AGTLTF+ GGS AFE AQP L MGK I+HAG G+GQ K+CNNMLL Sbjct: 122 APVSGGTSGAAAGTLTFICGGSDTAFERAQPVLNAMGKNIFHAGGPGAGQIAKICNNMLL 181 Query: 180 GILMIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMDTAPASKGYAGG 239 +LM+GTSEA+++G+ +G+DPKVLS IM SSG NWTLE YNPCPGVM+ P+SKGY GG Sbjct: 182 SVLMVGTSEALQMGIDHGLDPKVLSNIMKVSSGGNWTLEKYNPCPGVMENVPSSKGYQGG 241 Query: 240 FGVDLMLKDLGLAVENALATNCAIPLGATARNLYDIHSMNGAGKLDFSSIFNML 293 F VDLM+KDLGL+ E AL +N + P+GA AR+LY H+ G G DFSSIF Sbjct: 242 FMVDLMVKDLGLSFEAALLSNSSTPMGALARSLYVSHARQGNGHRDFSSIFEQF 295