BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0166.p (749 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1576 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolas... 881 0.0 NMA1991 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolas... 599 e-170 NMB1735 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolas... 597 e-170 PA0934 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolase... 582 e-166 relA [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/... 560 e-159 ZrelA [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases... 560 e-159 ECs3644 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolas... 560 e-159 STM2956 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolas... 559 e-159 VC2451 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolase... 548 e-155 HI0334 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolase... 543 e-154 >RSc1576 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases Rso Ralstonia solanacearum Length = 746 Score = 881 bits (2277), Expect = 0.0, Method: Compositional matrix adjust. Identities = 442/720 (61%), Positives = 535/720 (74%), Gaps = 19/720 (2%) Query: 39 ADRQILSGQNALQFSISVATVLTALNVDAATRIAALAFEVQMLHPELEEKLEERFGKEIA 98 D Q L+G+ + + +L L VDA + AA F + +L + E+ +E FG E+A Sbjct: 37 GDHQTLTGEPLVSHARGTVAILEGLRVDAPSLQAAALFLLPILATDNEKAIEPAFGGEVA 96 Query: 99 DLVGNVRQLMRFHSFS--FQPQQEVLRGKNAAQQAAAQIETLRKMLLAMATDMRAVLVRL 156 LV +VRQL+R + + P + + KN A+ AQ+E LRKMLLA A D+R VL+RL Sbjct: 97 RLVHDVRQLLRIGAIAGMASPAEAGVTRKNEAEARRAQVEALRKMLLAFAQDIRVVLIRL 156 Query: 157 ASRVATLRYFAETKQEDEASANYARQTFELYAPLANRLGIWQLKWELEDLSFRFLEPVTY 216 ASR+ +LR+ A+ K A AR+T ++YAPLANRLGIWQLKWELEDL FRF +P TY Sbjct: 157 ASRLQSLRWLAQNKLP--APEGMARETLDIYAPLANRLGIWQLKWELEDLGFRFEDPDTY 214 Query: 217 KRIAKMLEEKRLEREAFVANAIARLRAEMAAQDIRAEVSGRPKHIYSIWNKMRGKHIDFS 276 KRIA++L+EKR+ERE F+ AIARL+ + I AEVSGRPKHIYSIW KMRGK +DF+ Sbjct: 215 KRIARLLDEKRIEREQFIGEAIARLQQTLRDAGIHAEVSGRPKHIYSIWRKMRGKDLDFA 274 Query: 277 ELYDVRAFRVIVDDVKTCYAVLGIVHDIWTPIPEEFDDYISRPKQNGYQSLHTVVTAEDG 336 +LYDVRAFRVIVDD+K CY VLG VH +W PIP+EFDDYISRPK NGY+SLHTVV +DG Sbjct: 275 DLYDVRAFRVIVDDIKDCYTVLGFVHHMWQPIPKEFDDYISRPKTNGYKSLHTVVIGDDG 334 Query: 337 RALEVQIRTHEMHHFAEYGVAAHWRYKESGGSNFSAQ-----KYDEKIAWLRQLLAWKNE 391 RALEVQIRT EMHHFAEYGVAAHWRYKE+G ++ Q +YDEKIAWLRQLLAWK++ Sbjct: 335 RALEVQIRTREMHHFAEYGVAAHWRYKEAGSKGYAGQFSASERYDEKIAWLRQLLAWKDD 394 Query: 392 VTDAVVDQEEVRRDWVEKLKSATLDERIYVLTPQARVIELPSGATPIDFAYHLHSDVGHR 451 V ++ W E+LK LD+ IYVLTPQARVI LP GATP+DFAY+LHSD+GHR Sbjct: 395 AEHTVAQEDS---PW-EQLKHTELDDHIYVLTPQARVIALPQGATPVDFAYYLHSDLGHR 450 Query: 452 CRGARVDGVMVPLNTALKNGQTVEIITVKSGPGVGPSRDWLSPD--YAVSSRTRSKIRAW 509 CRGARVDG MVPLNT LKNGQTVEI+TVK G GPSRDWL+P+ Y S+R R+K+RAW Sbjct: 451 CRGARVDGTMVPLNTPLKNGQTVEIVTVKQG---GPSRDWLNPELHYLASNRARAKVRAW 507 Query: 510 FNAIEQQETLSVGRGLLEKTLQREGKTAVNLEELAQKLGFAKVDDLCLSLAKEEFSLRHV 569 FNA+E +ETL+ GR L++KTLQREGKTAVNLEELA KLGF D+L +AK+EFSLRHV Sbjct: 508 FNALELEETLAQGRILIDKTLQREGKTAVNLEELAAKLGFKTPDELYAMVAKDEFSLRHV 567 Query: 570 EQALHEGQEKKPEIDDETLITRKSRASSIVQGAKSGVLVVGTDGLLTQLARCCKPAPPDA 629 E L DDE IT+KSRA+S+ +GAKSGVLVVG D LLTQ++RCCKPAPPD Sbjct: 568 EAVLRTDGAPPAPADDEASITKKSRATSVARGAKSGVLVVGVDSLLTQMSRCCKPAPPDL 627 Query: 630 IAGFVTRGKGVSIHRVSCKNFAEMSSHAPERVIQTTWGAPARETVYPVDIFVLASDRQGL 689 I GFVTRG+GVSIHR +C F ++++ AP RVIQT WG E VYPVDI V A DRQGL Sbjct: 628 IVGFVTRGRGVSIHRQNCATFQQLAARAPGRVIQTEWGNRG-EAVYPVDIHVEALDRQGL 686 Query: 690 LRDISDIFLRDKINVIGVSTQSVKGHARMAFTAEIGSTEQLQKALTVIREVKGVIEAKRQ 749 LRDIS+I R+KINV GV T S KG A+M FTAE+ QLQ+AL +I EV GV+ A+R+ Sbjct: 687 LRDISEILSREKINVTGVRTLSSKGVAKMQFTAEVSEATQLQRALILIEEVTGVLSARRK 746 >NMA1991 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases NmA Neisseria meningitidis Z2491 Length = 769 Score = 599 bits (1544), Expect = e-170, Method: Compositional matrix adjust. Identities = 323/724 (44%), Positives = 444/724 (61%), Gaps = 30/724 (4%) Query: 28 AQALAELEPLYADRQILSGQNALQFSISVATVLTALNVDAATRIAALAFEVQMLHPELEE 87 A++LAE AD G+ + A ++ L++ A L ++ P+ Sbjct: 72 ARSLAEAH-YPADAATPYGEPLPDHFLGAAQMVHELDLLPDAVAATLLADIGRYVPDWNL 130 Query: 88 KLEERFGKEIADLVGNVRQLMRFHSFSFQPQQEVLRGKNAAQQAAAQIETLRKMLLAMAT 147 + ER +A+LV V ++ + F+ + ++ A Q ET+RKMLLAM T Sbjct: 131 LVSERCNSTVAELVKGVDEVQKLTHFAR------VDSLATPEERAQQAETMRKMLLAMVT 184 Query: 148 DMRAVLVRLASRVATLRYFAETKQEDEASANYARQTFELYAPLANRLGIWQLKWELEDLS 207 D+R VL++LA R TL++ + E A A++T +++APLANRLG+WQLKW+LEDL Sbjct: 185 DIRVVLIKLAMRTRTLQFLSNAPDSPEKRA-VAKETLDIFAPLANRLGVWQLKWQLEDLG 243 Query: 208 FRFLEPVTYKRIAKMLEEKRLEREAFVANAIARLRAEMAAQDIRAEVSGRPKHIYSIWNK 267 FR EP Y+ IA +L+EKR ER ++ N + LR E+ +I EV+GRPKHIYSI+ K Sbjct: 244 FRHQEPEKYREIALLLDEKRTERLEYIENFLNILRTELKKYNIHFEVAGRPKHIYSIYKK 303 Query: 268 MRGKHIDFSELYDVRAFRVIVDDVKTCYAVLGIVHDIWTPIPEEFDDYISRPKQNGYQSL 327 M K + F L+D+RA R++VD V CY LGIVH +W PIP EFDDYI+ PK NGY+SL Sbjct: 304 MVKKKLSFDGLFDIRAVRILVDTVPECYTTLGIVHSLWQPIPGEFDDYIANPKGNGYKSL 363 Query: 328 HTVVTAEDGRALEVQIRTHEMHHFAEYGVAAHWRYKESGGSNFSAQKYDEKIAWLRQLLA 387 HTV+ + + +EVQIRT +MH F E+GVAAHWRYKE GG SA Y++KIAWLRQLL Sbjct: 364 HTVIVGPEDKGVEVQIRTFDMHQFNEFGVAAHWRYKE-GGKGDSA--YEQKIAWLRQLLD 420 Query: 388 WKNEVTDAVVDQEEVRRDWVEKLKSATLDERIYVLTPQARVIELPSGATPIDFAYHLHSD 447 W+ + E + D K+ ++ IYVLTP +V+ LP+GATPIDFAY LHS Sbjct: 421 WRENMA------ESGKEDLAAAFKTELFNDTIYVLTPHGKVLSLPTGATPIDFAYALHSS 474 Query: 448 VGHRCRGARVDGVMVPLNTALKNGQTVEIITVKSGPGVGPSRDWLSPDYAVSSRTRSKIR 507 +G RCRGA+V+G +VPL+T L+NGQ VEIIT K G PS +WL + S++ KIR Sbjct: 475 IGDRCRGAKVEGQIVPLSTPLENGQRVEIITAKEG---HPSVNWLYEGWVKSNKAIGKIR 531 Query: 508 AWFNAIEQQETLSV---GRGLLEKTLQREGKTAVNLEELAQKLGFAKVDDLCLSLAKEEF 564 A+ I QQ +V GR L+K L + NL+ELA+ LG+ K +DL ++ + E Sbjct: 532 AY---IRQQNADTVREEGRVQLDKQLAKLTPKP-NLQELAENLGYKKPEDLYTAVGQGEI 587 Query: 565 SLRHVEQALHEGQEKKPEIDDETLITRKSRASSIVQGAKSGVLVVGTDGLLTQLARCCKP 624 S R +++A E P ET I ++S+ I +G K+GVL+ G DGL+T LA+CCKP Sbjct: 588 SNRAIQKACGTLNEPPPVPVSETTIVKQSK---IKKGGKNGVLIDGEDGLMTTLAKCCKP 644 Query: 625 APPDAIAGFVTRGKGVSIHRVSCKNFAEMSSHAPERVIQTTWGAPARETVYPVDIFVLAS 684 APPD I GFVTR +G+S+HR +C +F ++ HAPE+V+ +W A V+ VDI + A Sbjct: 645 APPDDIVGFVTRDRGISVHRKTCPSFRHLAEHAPEKVLDASWAALQEGQVFAVDIEIRAQ 704 Query: 685 DRQGLLRDISDIFLRDKINVIGVSTQSVKGHARMAFTAEIGSTEQLQKALTVIREVKGVI 744 DR GLLRD+SD R K+NV V TQS A M FT E+ L + L + +VKGV+ Sbjct: 705 DRSGLLRDVSDALARHKLNVTAVQTQSRDLEASMRFTLEVKQVTDLPRVLASLGDVKGVL 764 Query: 745 EAKR 748 R Sbjct: 765 SVTR 768 >NMB1735 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases Nme Neisseria meningitidis MC58 Length = 737 Score = 597 bits (1538), Expect = e-170, Method: Compositional matrix adjust. Identities = 312/680 (45%), Positives = 427/680 (62%), Gaps = 29/680 (4%) Query: 72 AALAFEVQMLHPELEEKLEERFGKEIADLVGNVRQLMRFHSFSFQPQQEVLRGKNAAQQA 131 A L ++ P+ + ER +A+LV V ++ + F+ + ++ Sbjct: 83 ATLLADIGRYVPDWNLLVSERCNSTVAELVKGVDEVQKLTHFAR------VDSLATPEER 136 Query: 132 AAQIETLRKMLLAMATDMRAVLVRLASRVATLRYFAETKQEDEASANYARQTFELYAPLA 191 A Q ET+RKMLLAM TD+R VL++LA R TL++ + E A A++T +++APLA Sbjct: 137 AQQAETMRKMLLAMVTDIRVVLIKLAMRTRTLQFLSNAPDSPEKRA-VAKETLDIFAPLA 195 Query: 192 NRLGIWQLKWELEDLSFRFLEPVTYKRIAKMLEEKRLEREAFVANAIARLRAEMAAQDIR 251 NRLG+WQLKW+LEDL FR +P Y+ IA +L+EKR ER ++ N + LR E+ ++ Sbjct: 196 NRLGVWQLKWQLEDLGFRHQKPEKYREIALLLDEKRTERLEYIENFLNILRGELKKYNVH 255 Query: 252 AEVSGRPKHIYSIWNKMRGKHIDFSELYDVRAFRVIVDDVKTCYAVLGIVHDIWTPIPEE 311 EV+GRPKHIYSI+ KM K + F L+D+RA R++VD V CY LGIVH +W PIP E Sbjct: 256 FEVAGRPKHIYSIYKKMVKKKLSFDGLFDIRAVRILVDTVPECYTTLGIVHSLWQPIPGE 315 Query: 312 FDDYISRPKQNGYQSLHTVVTAEDGRALEVQIRTHEMHHFAEYGVAAHWRYKESGGSNFS 371 FDDYI+ PK NGY+SLHTV+ + + +EVQIRT +MH F E+GVAAHWRYKE GG S Sbjct: 316 FDDYIANPKGNGYKSLHTVIVGPEDKGVEVQIRTFDMHQFNEFGVAAHWRYKE-GGKGDS 374 Query: 372 AQKYDEKIAWLRQLLAWKNEVTDAVVDQEEVRRDWVEKLKSATLDERIYVLTPQARVIEL 431 A Y++KIAWLRQLL W+ + E + D K+ ++ IYVLTP +V+ L Sbjct: 375 A--YEQKIAWLRQLLDWRENMA------ESGKEDLAAAFKTELFNDTIYVLTPHGKVLSL 426 Query: 432 PSGATPIDFAYHLHSDVGHRCRGARVDGVMVPLNTALKNGQTVEIITVKSGPGVGPSRDW 491 P+GATPIDFAY LHS +G RCRGA+V+G +VPL+T L+NGQ VEIIT K G PS +W Sbjct: 427 PTGATPIDFAYALHSSIGDRCRGAKVEGQIVPLSTPLENGQRVEIITAKEG---HPSVNW 483 Query: 492 LSPDYAVSSRTRSKIRAWFNAIEQQETLSV---GRGLLEKTLQREGKTAVNLEELAQKLG 548 L + S++ KIRA+ I QQ +V GR L+K L + NL+ELA+ LG Sbjct: 484 LYEGWVKSNKAIGKIRAY---IRQQNADTVREEGRVQLDKQLAKLTPKP-NLQELAENLG 539 Query: 549 FAKVDDLCLSLAKEEFSLRHVEQALHEGQEKKPEIDDETLITRKSRASSIVQGAKSGVLV 608 + K +DL ++ + E S R +++A E P ET I ++S+ I +G K+GVL+ Sbjct: 540 YKKPEDLYTAVGQGEISNRAIQKACGTLNEPPPVPVSETTIVKQSK---IKKGGKNGVLI 596 Query: 609 VGTDGLLTQLARCCKPAPPDAIAGFVTRGKGVSIHRVSCKNFAEMSSHAPERVIQTTWGA 668 G DGL+T LA+CCKPAPPD I GFVTR +G+S+HR +C +F ++ HAPE+V+ +W A Sbjct: 597 DGEDGLMTTLAKCCKPAPPDDIIGFVTRERGISVHRKTCPSFQHLAEHAPEKVLDASWAA 656 Query: 669 PARETVYPVDIFVLASDRQGLLRDISDIFLRDKINVIGVSTQSVKGHARMAFTAEIGSTE 728 V+ VDI + A DR GLLRD+SD R K+NV V TQS A M FT E+ Sbjct: 657 LQEGQVFAVDIEIRAQDRSGLLRDVSDALARHKLNVTAVQTQSRDLEASMRFTLEVKQVN 716 Query: 729 QLQKALTVIREVKGVIEAKR 748 L + L + +VKGV+ R Sbjct: 717 DLPRVLASLGDVKGVLSVTR 736 >PA0934 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases Pae Pseudomonas aeruginosa Length = 747 Score = 582 bits (1501), Expect = e-166, Method: Compositional matrix adjust. Identities = 303/708 (42%), Positives = 440/708 (62%), Gaps = 28/708 (3%) Query: 46 GQNALQFSISVATVLTALNVDAATRIAALAFEVQMLHPELEEKLEERFGKEIADLVGNVR 105 G ++ Q + +A +L L +D + +AA+ + E + + FG +A L+ V Sbjct: 61 GTSSFQTGLEIAEILADLKLDQESLVAAVIYRGVREGKITLEAVNKHFGPVVAKLIEGVL 120 Query: 106 QLMRFHSFSFQPQQEVLRGKNAAQQAAAQIETLRKMLLAMATDMRAVLVRLASRVATLRY 165 ++ S S P+ ++ G A Q+E LRKML+AM D+R L++LA R +R Sbjct: 121 RMAAI-SASLNPRHSMVLGTQA------QVENLRKMLVAMVDDVRVALIKLAERTCAIR- 172 Query: 166 FAETKQEDEASANYARQTFELYAPLANRLGIWQLKWELEDLSFRFLEPVTYKRIAKMLEE 225 A ++E AR+ F++YAPLA+RLGI +KWELEDLSFR+LEP YK+IAK+L E Sbjct: 173 -AVKNADEEKRHRVAREVFDIYAPLAHRLGIGHIKWELEDLSFRYLEPDQYKQIAKLLHE 231 Query: 226 KRLEREAFVANAIARLRAEMAAQDIRAEVSGRPKHIYSIWNKMRGKHIDFSELYDVRAFR 285 +RL+RE ++AN +++L+ +AA ++A++SGR KHIYSIW KM+ K +DFS++YDVRA R Sbjct: 232 RRLDREQYIANVMSQLKEALAATGVQADLSGRAKHIYSIWRKMQRKGLDFSQIYDVRAVR 291 Query: 286 VIVDDVKTCYAVLGIVHDIWTPIPEEFDDYISRPKQNGYQSLHTVVTAEDGRALEVQIRT 345 V+V +++ CY LGIVH +W IP+EFDDYI+ PK+NGY+SLHT V +G+ LEVQIRT Sbjct: 292 VLVPEMRDCYTALGIVHTLWRHIPKEFDDYIANPKENGYRSLHTAVIGPEGKVLEVQIRT 351 Query: 346 HEMHHFAEYGVAAHWRYKESGGSNFSAQKYDEKIAWLRQLLAWKNEVTDAVVDQEEVRRD 405 H MH AE GV AHWRYK + S+ Y+EKI+WLRQ+L W E+ D E++R D Sbjct: 352 HSMHEEAELGVCAHWRYKGT-DVKASSNHYEEKISWLRQVLEWHEELGDIGGLAEQLRVD 410 Query: 406 WVEKLKSATLDERIYVLTPQARVIELPSGATPIDFAYHLHSDVGHRCRGARVDGVMVPLN 465 +E +R+YV TP I+LP GATP+DFAY +H++VGH CRGA+++G +VPLN Sbjct: 411 -IEP-------DRVYVFTPDGHAIDLPKGATPLDFAYRVHTEVGHNCRGAKINGRIVPLN 462 Query: 466 TALKNGQTVEIITVKSGPGVGPSRDWLSPD--YAVSSRTRSKIRAWFNAIEQQETLSVGR 523 +L+ G+ VEIIT G GPSRDWL+ + Y +SR R+KI WF + + ++ G+ Sbjct: 463 YSLQTGEQVEIIT---GKHSGPSRDWLNSNLGYVTTSRARAKIVHWFKLQARDQNVAAGK 519 Query: 524 GLLEKTLQREGKTAVNLEELAQKLGFAKVDDLCLSLAKEEFSLRHVEQALHEGQEKKPEI 583 L+E+ L R V+ + LA+K +D+ +L + L H+ + Q +P+ Sbjct: 520 ALIERELSRLALPPVDFDRLAEKANVRTAEDMFAALGAGDLRLAHLVN--YAQQLVEPDR 577 Query: 584 DDETLITRKSRASSIVQGAKSGVLVVGTDGLLTQLARCCKPAPPDAIAGFVTRGKGVSIH 643 D E L + S I G + V + G LLTQ+A CC+P P D I G++T G+GV+IH Sbjct: 578 DSEQLELIPRKPSKIGHGKRGDVQIQGVGNLLTQMAGCCQPLPGDPIVGYITLGRGVTIH 637 Query: 644 RVSCKNFAEMSSHAPERVIQTTWGAPARETVYPVDIFVLASDRQGLLRDISDIFLRDKIN 703 R C +++ PER+IQ +WG P YPVDI + A DR GLLRD+S + L ++IN Sbjct: 638 RQDCATALQLAGREPERMIQVSWG-PEPVRTYPVDIAIRAYDRSGLLRDVSQVLLNERIN 696 Query: 704 VIGVSTQSVK--GHARMAFTAEIGSTEQLQKALTVIREVKGVIEAKRQ 749 V+ V+T+S K A M T EI + L + L + ++ +IEA+R Sbjct: 697 VLAVNTRSNKEDNTATMQLTIEIPGLDALGRLLARVSQLPNIIEARRN 744 >relA [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases Eco Escherichia coli K12 Length = 744 Score = 560 bits (1442), Expect = e-159, Method: Compositional matrix adjust. Identities = 289/706 (40%), Positives = 434/706 (61%), Gaps = 34/706 (4%) Query: 53 SISVATVLTALNVDAATRIAALAFEVQMLHPELEEKLEERFGKEIADLVGNVRQLMRFHS 112 + + +L+ L++D T AAL F + + E+ L E GK + +L+ VR + Sbjct: 59 GVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQ 118 Query: 113 FSFQPQQEVLRGKNAAQQAAAQIETLRKMLLAMATDMRAVLVRLASRVATLRYFAETKQE 172 L+ + ++ Q++ +R+MLLAM D R V+++LA R+A LR + ++ Sbjct: 119 ---------LKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPED 169 Query: 173 DEASANYARQTFELYAPLANRLGIWQLKWELEDLSFRFLEPVTYKRIAKMLEEKRLEREA 232 + A A++ +YAPLANRLGI QLKWELED FR+L P YKRIAK+L E+RL+RE Sbjct: 170 ERVLA--AKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREH 227 Query: 233 FVANAIARLRAEMAAQDIRAEVSGRPKHIYSIWNKMRGKHIDFSELYDVRAFRVIVDDVK 292 ++ + LRAEM A+ ++AEV GRPKHIYSIW KM+ K++ F EL+DVRA R++ + ++ Sbjct: 228 YIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQ 287 Query: 293 TCYAVLGIVHDIWTPIPEEFDDYISRPKQNGYQSLHTVVTAEDGRALEVQIRTHEMHHFA 352 CYA LGIVH + +P+EFDDY++ PK NGYQS+HTVV G+ +E+QIRT +MH A Sbjct: 288 DCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDA 347 Query: 353 EYGVAAHWRYKESGGSNFSAQKYDEKIAWLRQLLAWKNEVTDAVVDQEEVRRDWVEKLKS 412 E GVAAHW+YKE + + ++++IAWLR+L+AW+ E+ D+ +EVR S Sbjct: 348 ELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVR--------S 399 Query: 413 ATLDERIYVLTPQARVIELPSGATPIDFAYHLHSDVGHRCRGARVDGVMVPLNTALKNGQ 472 D+R+YV TP+ V++LP+G+TP+DFAYH+HSDVGHRC GA++ G +VP L+ G Sbjct: 400 QVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGD 459 Query: 473 TVEIITVKSGPGVGPSRDWLSPD--YAVSSRTRSKIRAWFNAIEQQETLSVGRGLLEKTL 530 +EIIT K PSRDWL+P+ Y +SR RSKI AWF ++ + + GR +L+ L Sbjct: 460 QIEIITQKQP---NPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDEL 516 Query: 531 QREGKTAVNLEE-LAQKLGFAKVDDLCLSLAKEEFSLRHVEQALHEGQEKKPEIDDETL- 588 + G + E+ L + F VD+L ++ + L + L + Q KP +++ Sbjct: 517 EHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFL-QSQFNKPSAEEQDAA 575 Query: 589 ----ITRKSRASSIVQGAKSGVLVVGTDGLLTQLARCCKPAPPDAIAGFVTRGKGVSIHR 644 + +KS V+V G L+ +ARCC+P P D I GF+T+G+G+S+HR Sbjct: 576 ALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHR 635 Query: 645 VSCKNFAEMSSHAPERVIQTTWGAPARETVYPVDIFVLASDRQGLLRDISDIFLRDKINV 704 C+ AE+ SHAPER++ WG + Y + + V+A+DR GLLRDI+ I +K+NV Sbjct: 636 ADCEQLAELRSHAPERIVDAVWGE-SYSAGYSLVVRVVANDRSGLLRDITTILANEKVNV 694 Query: 705 IGVSTQSVKGH--ARMAFTAEIGSTEQLQKALTVIREVKGVIEAKR 748 +GV+++S A + T EI + + L + L + +V VI+A+R Sbjct: 695 LGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARR 740 >ZrelA [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases EcZ Escherichia coli O157:H7 EDL933 Length = 744 Score = 560 bits (1442), Expect = e-159, Method: Compositional matrix adjust. Identities = 289/706 (40%), Positives = 434/706 (61%), Gaps = 34/706 (4%) Query: 53 SISVATVLTALNVDAATRIAALAFEVQMLHPELEEKLEERFGKEIADLVGNVRQLMRFHS 112 + + +L+ L++D T AAL F + + E+ L E GK + +L+ VR + Sbjct: 59 GVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQ 118 Query: 113 FSFQPQQEVLRGKNAAQQAAAQIETLRKMLLAMATDMRAVLVRLASRVATLRYFAETKQE 172 L+ + ++ Q++ +R+MLLAM D R V+++LA R+A LR + ++ Sbjct: 119 ---------LKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPED 169 Query: 173 DEASANYARQTFELYAPLANRLGIWQLKWELEDLSFRFLEPVTYKRIAKMLEEKRLEREA 232 + A A++ +YAPLANRLGI QLKWELED FR+L P YKRIAK+L E+RL+RE Sbjct: 170 ERVLA--AKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREH 227 Query: 233 FVANAIARLRAEMAAQDIRAEVSGRPKHIYSIWNKMRGKHIDFSELYDVRAFRVIVDDVK 292 ++ + LRAEM A+ ++AEV GRPKHIYSIW KM+ K++ F EL+DVRA R++ + ++ Sbjct: 228 YIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQ 287 Query: 293 TCYAVLGIVHDIWTPIPEEFDDYISRPKQNGYQSLHTVVTAEDGRALEVQIRTHEMHHFA 352 CYA LGIVH + +P+EFDDY++ PK NGYQS+HTVV G+ +E+QIRT +MH A Sbjct: 288 DCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDA 347 Query: 353 EYGVAAHWRYKESGGSNFSAQKYDEKIAWLRQLLAWKNEVTDAVVDQEEVRRDWVEKLKS 412 E GVAAHW+YKE + + ++++IAWLR+L+AW+ E+ D+ +EVR S Sbjct: 348 ELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVR--------S 399 Query: 413 ATLDERIYVLTPQARVIELPSGATPIDFAYHLHSDVGHRCRGARVDGVMVPLNTALKNGQ 472 D+R+YV TP+ V++LP+G+TP+DFAYH+HSDVGHRC GA++ G +VP L+ G Sbjct: 400 QVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGD 459 Query: 473 TVEIITVKSGPGVGPSRDWLSPD--YAVSSRTRSKIRAWFNAIEQQETLSVGRGLLEKTL 530 +EIIT K PSRDWL+P+ Y +SR RSKI AWF ++ + + GR +L+ L Sbjct: 460 QIEIITQKQP---NPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDEL 516 Query: 531 QREGKTAVNLEE-LAQKLGFAKVDDLCLSLAKEEFSLRHVEQALHEGQEKKPEIDDETL- 588 + G + E+ L + F VD+L ++ + L + L + Q KP +++ Sbjct: 517 EHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFL-QSQFNKPSAEEQDAA 575 Query: 589 ----ITRKSRASSIVQGAKSGVLVVGTDGLLTQLARCCKPAPPDAIAGFVTRGKGVSIHR 644 + +KS V+V G L+ +ARCC+P P D I GF+T+G+G+S+HR Sbjct: 576 ALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHR 635 Query: 645 VSCKNFAEMSSHAPERVIQTTWGAPARETVYPVDIFVLASDRQGLLRDISDIFLRDKINV 704 C+ AE+ SHAPER++ WG + Y + + V+A+DR GLLRDI+ I +K+NV Sbjct: 636 ADCEQLAELRSHAPERIVDAVWGE-SYSAGYSLVVRVVANDRSGLLRDITTILANEKVNV 694 Query: 705 IGVSTQSVKGH--ARMAFTAEIGSTEQLQKALTVIREVKGVIEAKR 748 +GV+++S A + T EI + + L + L + +V VI+A+R Sbjct: 695 LGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARR 740 >ECs3644 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases Ecs Escherichia coli O157:H7 Length = 744 Score = 560 bits (1442), Expect = e-159, Method: Compositional matrix adjust. Identities = 289/706 (40%), Positives = 434/706 (61%), Gaps = 34/706 (4%) Query: 53 SISVATVLTALNVDAATRIAALAFEVQMLHPELEEKLEERFGKEIADLVGNVRQLMRFHS 112 + + +L+ L++D T AAL F + + E+ L E GK + +L+ VR + Sbjct: 59 GVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQ 118 Query: 113 FSFQPQQEVLRGKNAAQQAAAQIETLRKMLLAMATDMRAVLVRLASRVATLRYFAETKQE 172 L+ + ++ Q++ +R+MLLAM D R V+++LA R+A LR + ++ Sbjct: 119 ---------LKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPED 169 Query: 173 DEASANYARQTFELYAPLANRLGIWQLKWELEDLSFRFLEPVTYKRIAKMLEEKRLEREA 232 + A A++ +YAPLANRLGI QLKWELED FR+L P YKRIAK+L E+RL+RE Sbjct: 170 ERVLA--AKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREH 227 Query: 233 FVANAIARLRAEMAAQDIRAEVSGRPKHIYSIWNKMRGKHIDFSELYDVRAFRVIVDDVK 292 ++ + LRAEM A+ ++AEV GRPKHIYSIW KM+ K++ F EL+DVRA R++ + ++ Sbjct: 228 YIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQ 287 Query: 293 TCYAVLGIVHDIWTPIPEEFDDYISRPKQNGYQSLHTVVTAEDGRALEVQIRTHEMHHFA 352 CYA LGIVH + +P+EFDDY++ PK NGYQS+HTVV G+ +E+QIRT +MH A Sbjct: 288 DCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDA 347 Query: 353 EYGVAAHWRYKESGGSNFSAQKYDEKIAWLRQLLAWKNEVTDAVVDQEEVRRDWVEKLKS 412 E GVAAHW+YKE + + ++++IAWLR+L+AW+ E+ D+ +EVR S Sbjct: 348 ELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVR--------S 399 Query: 413 ATLDERIYVLTPQARVIELPSGATPIDFAYHLHSDVGHRCRGARVDGVMVPLNTALKNGQ 472 D+R+YV TP+ V++LP+G+TP+DFAYH+HSDVGHRC GA++ G +VP L+ G Sbjct: 400 QVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGD 459 Query: 473 TVEIITVKSGPGVGPSRDWLSPD--YAVSSRTRSKIRAWFNAIEQQETLSVGRGLLEKTL 530 +EIIT K PSRDWL+P+ Y +SR RSKI AWF ++ + + GR +L+ L Sbjct: 460 QIEIITQKQP---NPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDEL 516 Query: 531 QREGKTAVNLEE-LAQKLGFAKVDDLCLSLAKEEFSLRHVEQALHEGQEKKPEIDDETL- 588 + G + E+ L + F VD+L ++ + L + L + Q KP +++ Sbjct: 517 EHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFL-QSQFNKPSAEEQDAA 575 Query: 589 ----ITRKSRASSIVQGAKSGVLVVGTDGLLTQLARCCKPAPPDAIAGFVTRGKGVSIHR 644 + +KS V+V G L+ +ARCC+P P D I GF+T+G+G+S+HR Sbjct: 576 ALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHR 635 Query: 645 VSCKNFAEMSSHAPERVIQTTWGAPARETVYPVDIFVLASDRQGLLRDISDIFLRDKINV 704 C+ AE+ SHAPER++ WG + Y + + V+A+DR GLLRDI+ I +K+NV Sbjct: 636 ADCEQLAELRSHAPERIVDAVWGE-SYSAGYSLVVRVVANDRSGLLRDITTILANEKVNV 694 Query: 705 IGVSTQSVKGH--ARMAFTAEIGSTEQLQKALTVIREVKGVIEAKR 748 +GV+++S A + T EI + + L + L + +V VI+A+R Sbjct: 695 LGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARR 740 >STM2956 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases Sty Salmonella typhimurium LT2 Length = 744 Score = 559 bits (1441), Expect = e-159, Method: Compositional matrix adjust. Identities = 291/706 (41%), Positives = 434/706 (61%), Gaps = 34/706 (4%) Query: 53 SISVATVLTALNVDAATRIAALAFEVQMLHPELEEKLEERFGKEIADLVGNVRQLMRFHS 112 + + +L+ L++D T AAL F + + E+ L E GK I L+ VR + Sbjct: 59 GVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSIVTLIHGVRDMAAIRQ 118 Query: 113 FSFQPQQEVLRGKNAAQQAAAQIETLRKMLLAMATDMRAVLVRLASRVATLRYFAETKQE 172 + V ++ Q++ +R+MLLAM D R V+++LA R+A LR E ++ Sbjct: 119 LNATHNDSV---------SSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKEAPED 169 Query: 173 DEASANYARQTFELYAPLANRLGIWQLKWELEDLSFRFLEPVTYKRIAKMLEEKRLEREA 232 + A A++ +YAPLANRLGI QLKWELED FR+L P YKRIAK+L E+RL+RE Sbjct: 170 ERVLA--AKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPAEYKRIAKLLHERRLDREH 227 Query: 233 FVANAIARLRAEMAAQDIRAEVSGRPKHIYSIWNKMRGKHIDFSELYDVRAFRVIVDDVK 292 ++ + LRAEM + ++AEV GRPKHIYSIW KM+ KH+ F EL+DVRA R++ + ++ Sbjct: 228 YIEEFVGHLRAEMKNEGVQAEVYGRPKHIYSIWRKMQKKHLAFDELFDVRAVRIVAERLQ 287 Query: 293 TCYAVLGIVHDIWTPIPEEFDDYISRPKQNGYQSLHTVVTAEDGRALEVQIRTHEMHHFA 352 CYA LGIVH + +P+EFDDY++ PK NGYQS+HTVV G+ +E+QIRT +MH A Sbjct: 288 DCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDA 347 Query: 353 EYGVAAHWRYKESGGSNFSAQKYDEKIAWLRQLLAWKNEVTDAVVDQEEVRRDWVEKLKS 412 E GVAAHW+YKE S ++++IAWLR+L+AW+ E+ D+ +EVR S Sbjct: 348 ELGVAAHWKYKEGAASGGVRSGHEDRIAWLRKLIAWQEEMADSGEMLDEVR--------S 399 Query: 413 ATLDERIYVLTPQARVIELPSGATPIDFAYHLHSDVGHRCRGARVDGVMVPLNTALKNGQ 472 D+R+YV TP+ V++LP+G+TP+DFAYH+HSDVGHRC GA++ G +VP L+ G Sbjct: 400 QVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGD 459 Query: 473 TVEIITVKSGPGVGPSRDWLSPD--YAVSSRTRSKIRAWFNAIEQQETLSVGRGLLEKTL 530 +EIIT K PSRDWL+P+ Y +SR RSKI AWF ++ + + GR +L+ L Sbjct: 460 QIEIITQKQP---NPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNIQAGRQILDDEL 516 Query: 531 QREGKTAVNLEE-LAQKLGFAKVDDLCLSLAKEEFSLRHVEQALHEGQEKKPEIDDETL- 588 G + E+ L + F ++++L ++ + L + L + Q KP +++ Sbjct: 517 AHLGISLKEAEKHLLPRYNFNELEELLAAIGGGDIRLNQMVNFL-QSQFNKPSAEEQDAA 575 Query: 589 ----ITRKSRASSIVQGAKSGVLVVGTDGLLTQLARCCKPAPPDAIAGFVTRGKGVSIHR 644 + +K+ A + V+V G L+ +ARCC+P P D I GF+T+G+G+S+HR Sbjct: 576 ALKQLQQKTYAPQNRRKDDGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHR 635 Query: 645 VSCKNFAEMSSHAPERVIQTTWGAPARETVYPVDIFVLASDRQGLLRDISDIFLRDKINV 704 C+ AE+ SHAPER+++ WG + Y + + V A+DR GLLRDI+ I +K+NV Sbjct: 636 ADCEQLAELRSHAPERIVEAVWGE-SYSAGYSLVVRVQANDRSGLLRDITTILANEKVNV 694 Query: 705 IGVSTQS-VKGH-ARMAFTAEIGSTEQLQKALTVIREVKGVIEAKR 748 +GV+++S +K A + T EI + + L + L + +V VI+A+R Sbjct: 695 LGVASRSDIKQQIATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARR 740 >VC2451 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases Vch Vibrio cholerae Length = 738 Score = 548 bits (1412), Expect = e-155, Method: Compositional matrix adjust. Identities = 296/733 (40%), Positives = 439/733 (59%), Gaps = 44/733 (6%) Query: 32 AELEPLYAD-RQILSG--QNALQF--SISVATVLTALNVDAATRIAALAFEVQMLHPELE 86 A+L +Y D Q+L+G Q L + +L L++D T +AAL F + Sbjct: 32 AKLTAVYRDCEQLLAGNPQGPLLLWRGREMIEILITLSMDRPTLVAALLFPIATSGVLDN 91 Query: 87 EKLEERFGKEIADLVGNVRQLMRFHSFSFQPQQEVLRGKNAAQQAAAQIETLRKMLLAMA 146 E LEE +G+E+ L+ V ++ + +A+AQ++ +R+MLLAM Sbjct: 92 ESLEEGYGREVVKLIHGVEEMAAIGQLNVTMH---------GSEASAQVDNVRRMLLAMV 142 Query: 147 TDMRAVLVRLASRVATLRYFAETKQE-DEASANYARQTFELYAPLANRLGIWQLKWELED 205 D R V+++LA R+ LR E K E DE A++ +YAPLANRLGI QLKWE+ED Sbjct: 143 DDFRCVVIKLAERICNLR---EVKNEPDEVRRVAAKECANIYAPLANRLGIGQLKWEIED 199 Query: 206 LSFRFLEPVTYKRIAKMLEEKRLEREAFVANAIARLRAEMAAQDIRAEVSGRPKHIYSIW 265 +FR+ +P TYK+IAK L E+R+ RE ++ + ++ LRAEM I AEVSGRPKHIYSIW Sbjct: 200 YAFRYQQPDTYKQIAKQLSERRIVREQYIRDFVSDLRAEMKQSGINAEVSGRPKHIYSIW 259 Query: 266 NKMRGKHIDFSELYDVRAFRVIVDDVKTCYAVLGIVHDIWTPIPEEFDDYISRPKQNGYQ 325 KM+ K + F EL+DVRA R+I D ++ CYA LGIVH + +P EFDDY++ PK NGYQ Sbjct: 260 RKMQKKSLAFDELFDVRAVRIIADKLQDCYAALGIVHTKYKHLPNEFDDYVANPKPNGYQ 319 Query: 326 SLHTVVTAEDGRALEVQIRTHEMHHFAEYGVAAHWRYKESGGSNFSAQKYDEKIAWLRQL 385 S+HTV+ +G+ +E+QIRT +MH +E GVAAHW+YKE GS+ + YDEKI WLR+L Sbjct: 320 SIHTVILGPEGKTIEIQIRTKQMHEESELGVAAHWKYKE--GSSAARSGYDEKITWLRKL 377 Query: 386 LAWKNEVTDAVVDQEEVRRDWVEKLKSATLDERIYVLTPQARVIELPSGATPIDFAYHLH 445 L W+ E++D+ + +++L+S D+R+Y TP+ V++LP GATP+DFAYH+H Sbjct: 378 LDWQEEMSDS--------GEMLDELRSQVFDDRVYAFTPKGDVVDLPMGATPLDFAYHIH 429 Query: 446 SDVGHRCRGARVDGVMVPLNTALKNGQTVEIITVKSGPGVGPSRDWLSPD--YAVSSRTR 503 S+VGHRC GA+V G +VP L+ G VEIIT K PSRDWL+P + S R R Sbjct: 430 SEVGHRCIGAKVAGRIVPFTHKLQMGDQVEIITAKEP---NPSRDWLNPSLGFVHSGRAR 486 Query: 504 SKIRAWFNAIEQQETLSVGRGLLEKTLQREGKTAVNLEELA-QKLGFAKVDDLCLSLAKE 562 +KI AWF +++ L GR +LE L + G + E A ++ VD++ + + Sbjct: 487 AKINAWFRKQSREKNLEAGREILEIELAKIGANLKHAEAYALKRFNVNSVDEMYVGIGSG 546 Query: 563 EFSLRHVEQALHEGQEKKPEIDDETLITRKSRASSIV---QGAKSGVLVVGTDGLLTQLA 619 + + + ++ K +++ L K + + + + K V+V G D L+T LA Sbjct: 547 DLRINQIVNHINALVNKPTAEEEDKLALEKLQENKTLTPNRPHKDAVVVEGVDNLMTHLA 606 Query: 620 RCCKPAPPDAIAGFVTRGKGVSIHRVSCKNFAEMSSHAPERVIQTTWGAPARETVYPVDI 679 RCC+P P D I G++T+G+G+S+HR C+ E+S HAPER+I T WG+ + Y + + Sbjct: 607 RCCQPIPGDEIRGYITQGRGISVHRSDCEQLEELSLHAPERIIDTVWGSGFVGS-YLLTV 665 Query: 680 FVLASDRQGLLRDISDIFLRDKINVIGVSTQSVKGHAR----MAFTAEIGSTEQLQKALT 735 V A +R GLL+DI+ + +K+ V + ++S + R M F E+ + E L + Sbjct: 666 RVEAMERSGLLKDITTLLANEKVKVASMKSRS--DYKRQIIIMDFDLEVNNVEALARVSK 723 Query: 736 VIREVKGVIEAKR 748 I ++K V+ KR Sbjct: 724 RIEQIKDVMLVKR 736 >HI0334 [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases Hin Haemophilus influenzae Length = 743 Score = 543 bits (1399), Expect = e-154, Method: Compositional matrix adjust. Identities = 291/711 (40%), Positives = 441/711 (62%), Gaps = 39/711 (5%) Query: 50 LQFSISVATVLTALNVDAATRIAALAFEVQMLHPELEEKLEERFGKEIADLVGNVRQLMR 109 LQ + + +L LN+DA T + A+ F + E L+E+FG +I L+ V ++ Sbjct: 59 LQSGVEMVEILHELNMDAETLLTAMLFPIVANKLTDWESLKEKFGAKITKLLKGVLEM-- 116 Query: 110 FHSFSFQPQQEVLRGKNAAQQAAA-QIETLRKMLLAMATDMRAVLVRLASRVATLRYFAE 168 + +R NA+ A A Q++ +R+MLLAM D R V+++LA R+ LR AE Sbjct: 117 ----------DNIRQLNASHSANALQVDNVRRMLLAMVDDFRCVIIKLAERITFLRD-AE 165 Query: 169 TKQEDEASANYARQTFELYAPLANRLGIWQLKWELEDLSFRFLEPVTYKRIAKMLEEKRL 228 + +E ++ +YAPLANRLGI QLKWELED FR+L P Y+ IAK+L+E+RL Sbjct: 166 HRCAEEDKVLAVKECSYIYAPLANRLGIGQLKWELEDYCFRYLHPEQYRAIAKLLQERRL 225 Query: 229 EREAFVANAIARLRAEMAAQDIRAEVSGRPKHIYSIWNKMRGKHIDFSELYDVRAFRVIV 288 +RE ++A+ ++ L + + EV GRPKHIYSIW KM+ KH++FS LYDVRA R+IV Sbjct: 226 DREHYIADFVSELSGYLRENIEQVEVYGRPKHIYSIWRKMQKKHLEFSGLYDVRAVRIIV 285 Query: 289 DDVKTCYAVLGIVHDIWTPIPEEFDDYISRPKQNGYQSLHTVVTAEDGRALEVQIRTHEM 348 ++ CY LGIVH + +P+EFDDY++ PK NGYQS+HTVV + G+ +EVQIRT +M Sbjct: 286 QKLQDCYTALGIVHTQFKHLPKEFDDYVANPKPNGYQSIHTVVLGKGGKPIEVQIRTQQM 345 Query: 349 HHFAEYGVAAHWRYKESGGSNFSAQKYDEKIAWLRQLLAWKNEVTDAVVDQEEVRRDWVE 408 H AE G+AAHW+YKE + SA Y+EKIAWLR+LLAW++++TD+ EV + Sbjct: 346 HDDAELGMAAHWKYKEGNTGSMSA--YEEKIAWLRKLLAWQDDITDS----GEV----LA 395 Query: 409 KLKSATLDERIYVLTPQARVIELPSGATPIDFAYHLHSDVGHRCRGARVDGVMVPLNTAL 468 +L+S D+R+YV TP+ V++LP+G+TP+DFAY +HS++GHRC GA+V G +VP L Sbjct: 396 ELRSQVFDDRVYVFTPKGEVVDLPTGSTPLDFAYAIHSEIGHRCIGAKVAGRIVPFTYQL 455 Query: 469 KNGQTVEIITVKSGPGVGPSRDWLSPD--YAVSSRTRSKIRAWFNAIEQQETLSVGRGLL 526 + G ++IIT K+ PSRDWL+P+ + ++++R+KI+AWF ++ + + G+ LL Sbjct: 456 QMGDQIDIITQKNP---NPSRDWLNPNLGFTHTAKSRAKIQAWFKKQDRDKNIPAGKELL 512 Query: 527 EKTLQREGKTAVNLEELA-QKLGFAKVDDLCLSLAKEEFSLRHVEQALHEGQEK--KPEI 583 + L + +E A + +DDL + + L ++ L K E Sbjct: 513 DNELALLNLSIKQVEPYALPRYNLKNLDDLYAGIGSGDIRLNNLIHFLQSKLIKVTAEEA 572 Query: 584 DDETL--ITRKSRASSIVQGAKSG--VLVVGTDGLLTQLARCCKPAPPDAIAGFVTRGKG 639 D E L + KS +S + K+ V+V G D L+ +ARCC+P P DAI G++T G+G Sbjct: 573 DQEILRHVANKSAVNSQQKSEKNNGCVIVEGVDNLMHHIARCCQPIPGDAIVGYITMGRG 632 Query: 640 VSIHRVSCKNFAEMSSHAPERVIQTTWGAPARETVYPVDIFVLASDRQGLLRDISDIFLR 699 +SIHR C+ F ++ + PERV+++ WG + + ++I ++A DR GLLRDI+ + Sbjct: 633 ISIHRADCEQFLDLQAAHPERVVESIWGE-NYASGFHINIRIVAGDRNGLLRDITTVLAN 691 Query: 700 DKINVIGVSTQ--SVKGHARMAFTAEIGSTEQLQKALTVIREVKGVIEAKR 748 +KI+V+GVS++ + K A + E+ + E L K L + ++ VIEAKR Sbjct: 692 EKISVLGVSSRADTKKQLATIDMEIELHNVESLSKILARLAKLDDVIEAKR 742