BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0037.0146.p         (418 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

PAB0724 [GEPR] COG0477 Permeases of the major facilitator superf...    71   5e-12
mlr4214 [GEPR] COG0477 Permeases of the major facilitator superf...    63   1e-09
TM1336 [GEPR] COG0477 Permeases of the major facilitator superfa...    61   6e-09

>PAB0724 [GEPR] COG0477 Permeases of the major facilitator superfamily Pab
           Pyrococcus abyssi
          Length = 418

 Score = 71.2 bits (173), Expect = 5e-12,   Method: Compositional matrix adjust.
 Identities = 85/352 (24%), Positives = 162/352 (46%), Gaps = 15/352 (4%)

Query: 31  VLLQMLMFELTQSAFQVMLLVLAELAPMLLLGPWAGAVTDRSGLRRVLGGSCVARLALLL 90
           V L + + ++T SA  + L VLA+L P ++  P AG   DR   ++++ G  + R  +LL
Sbjct: 24  VALPLYVLDVTHSAKIMTLFVLADLIPSIITTPIAGVFGDRYDRKKIMVGFDLIR-GVLL 82

Query: 91  LLALPAARSSAAPLLAVAALTAVCNRFFSPAANALLPCLVCPGQLPAANACAMAARMAGM 150
            L +     +   LL V  + A+ N FFS    A+ P LV P +L  AN+  M+A +   
Sbjct: 83  FLVIAFNFLTIRCLLVVQVIMAIMNAFFSAGTGAMYPDLVKPEELERANSIVMSASIISR 142

Query: 151 ALGAMVGGVLAGVAGNDATILTMGLLMLGCGGLSLSLPERRRLAATQSPAWRWTLVVQCV 210
            +G  +GG + G  G    IL   +   G G   + +    +    +  +     + + +
Sbjct: 143 LVGPAIGGFVYGFGGIKLAILMNAISFFGSGLFEIFIKYEWKTRNIEGFSDFVRDIKEGL 202

Query: 211 AAPGRSGWLAIAAGMLV-MAALGSIEILAIVY---VKQVLHRPAADVGLLFGAYGAGVVL 266
                + +++   G+++ + ALG+    +I+Y   ++++L   +   GL+  A+  G ++
Sbjct: 203 KFIMSNSFISTLIGLVILLNALGA-PFASIIYPYAMREILKFSSQQFGLVESAFMLGALI 261

Query: 267 GLVLSSWHRIVARSDDVIRLSLLLMCVAIGLVSQVERL-----GSAALLVSMAGLAEGM- 320
           G ++            + RL L+   V +  +  +         SA +L+ + G   GM 
Sbjct: 262 GNLIVGAFLGAKAGRYIFRLFLVNGAVELIFILIISPFLALPRNSAFMLLLVLGATMGMA 321

Query: 321 --VMSLGLLRLYQTVDPSRL-GRATALLDSASGAAFLLAVVVTGLLADTVAA 369
             ++++ L    Q   PS + GR  + ++  +  A  L++VV G L DT+ A
Sbjct: 322 GAMINVPLASKLQRAVPSEIRGRVFSTMEMLARIANPLSLVVVGPLVDTIGA 373


>mlr4214 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo
           Mesorhizobium loti
          Length = 412

 Score = 62.8 bits (151), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 55/183 (30%), Positives = 87/183 (47%), Gaps = 3/183 (1%)

Query: 19  QFLVSMADWMLIVLLQMLMFELTQSAFQVMLLVLAELAPMLLLGPWAGAVTDRSGLRRVL 78
           +FL + A  ++ V +   M++LT+  F + ++ + +  P LLL    GAV DR G R ++
Sbjct: 27  RFLTTFATMVVSVAVGWQMYDLTRDPFDLGIVGIVQFLPSLLLVLVTGAVADRFGRRLIM 86

Query: 79  GGSCVARLALLLLLALPAARSSAAPL--LAVAALTAVCNRFFSPAANALLPCLVCPGQLP 136
             + V      L L     RS + PL    V A+  V   FF PA+ +L   LV P    
Sbjct: 87  ALAVVVEAICALALLALTLRSISGPLPIFCVLAMFGVARAFFGPASASLFANLVPPEDFA 146

Query: 137 AANACAMAARMAGMALGAMVGGVLAGVAGNDATILTMGLLMLGCGGLSLSLPERRRLAAT 196
            A A   +A      +G + GG+L GV+  +    T  +LML  G L  ++P+  +   T
Sbjct: 147 NAIAWNSSAWQTATIVGPVAGGLLYGVS-PEVAYGTAAVLMLASGLLIFTIPKPAQRTET 205

Query: 197 QSP 199
           + P
Sbjct: 206 EKP 208


>TM1336 [GEPR] COG0477 Permeases of the major facilitator superfamily Tma
           Thermotoga maritima
          Length = 390

 Score = 60.8 bits (146), Expect = 6e-09,   Method: Compositional matrix adjust.
 Identities = 47/171 (27%), Positives = 82/171 (47%), Gaps = 5/171 (2%)

Query: 37  MFELTQSAFQVMLLVLAELAPMLLLGPWAGAVTDRSGLRRVLGGSCVARLALLLLLALPA 96
           ++  T S+  V L +++   P +++ P+AG V DR   R ++    + R  L + L L  
Sbjct: 30  LYSKTGSSEYVGLFMISSFLPAIIVSPFAGTVVDRHSRRNMMVVMDILRGVLFMYLFLME 89

Query: 97  ARS--SAAPLLAVAALTAVCNRFFSPAANALLPCLVCPGQLPAANACAMAARMAGMALGA 154
             S  + A LL V  L +V + FF+PA ++LLP LV    L  AN+     +     LG 
Sbjct: 90  YFSELTMALLLIVTVLVSVFDSFFNPAVDSLLPDLVRKENLVRANSLYRLLKNLSKILGP 149

Query: 155 MVGGVLAGVAGNDATIL--TMGLLMLGCGGLSLSLPERR-RLAATQSPAWR 202
            +G +L  V G    IL  ++  L+ G   + + + E+  +  + +   W+
Sbjct: 150 ALGSLLLKVVGLAGVILINSLSFLISGIFEMFIKVEEKHLKKVSKERNMWQ 200