BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0136.p (621 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1071 [L] COG0322 Nuclease subunit of the excinuclease complex... 907 0.0 NMA1540 [L] COG0322 Nuclease subunit of the excinuclease complex... 631 e-180 NMB1326 [L] COG0322 Nuclease subunit of the excinuclease complex... 618 e-176 PA2585 [L] COG0322 Nuclease subunit of the excinuclease complex ... 574 e-163 XF2311 [L] COG0322 Nuclease subunit of the excinuclease complex ... 529 e-150 VC1214 [L] COG0322 Nuclease subunit of the excinuclease complex ... 520 e-147 STM1946 [L] COG0322 Nuclease subunit of the excinuclease complex... 520 e-147 uvrC [L] COG0322 Nuclease subunit of the excinuclease complex Ec... 514 e-145 ZuvrC [L] COG0322 Nuclease subunit of the excinuclease complex E... 514 e-145 ECs2651 [L] COG0322 Nuclease subunit of the excinuclease complex... 514 e-145 >RSc1071 [L] COG0322 Nuclease subunit of the excinuclease complex Rso Ralstonia solanacearum Length = 654 Score = 907 bits (2343), Expect = 0.0, Method: Compositional matrix adjust. Identities = 455/648 (70%), Positives = 518/648 (79%), Gaps = 33/648 (5%) Query: 5 PASPLPDPREAVLET---VARLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLT 61 P +P DP EA + +ARLP LPGVYRYFDA+ +VLYVGKARDLKKRVSSYF KTL Sbjct: 9 PPAPAVDPSEAAFDAKAHIARLPSLPGVYRYFDAQGSVLYVGKARDLKKRVSSYFTKTLL 68 Query: 62 SPRIAMMVERIARLETTVTRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAF 121 SPRIAMMV +IA +ETTV RSEAEALLLENNLIK L PR+NILFRDDKSYPYLK+T HA+ Sbjct: 69 SPRIAMMVAKIAHIETTVVRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTQHAY 128 Query: 122 PRMAYYRGAVDKRNQYFGPFPNAGAVKESIQILQKVFLLRTCEDTVFSNRTRPCLLHQIH 181 PRMAYYRGA D+++QYFGPFP+A AV+ES+QILQKVF LRTCEDTVF+NRTRPCLLHQIH Sbjct: 129 PRMAYYRGATDRKHQYFGPFPSAHAVRESMQILQKVFQLRTCEDTVFNNRTRPCLLHQIH 188 Query: 182 RCSGPCVNLVSREDYAIDVENASKFLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQI 241 RC+ PCV +S EDYA DV NA+ FL GRQ EVM+ L+ KM AA L+FEQAA VRDQI Sbjct: 189 RCTAPCVQAISAEDYARDVANAAGFLLGRQDEVMQTLQDKMQRHAAALEFEQAATVRDQI 248 Query: 242 GSLSSVLHQQSMETVSDA-DIDIIAVVVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAM 300 G+LS+VL +QS+E V A DIDI+AV ++GG ACVNLAMVRGGRHLGD+AYFPTHV++ Sbjct: 249 GALSTVLTRQSVEEVGQASDIDILAVAIKGGHACVNLAMVRGGRHLGDKAYFPTHVEEG- 307 Query: 301 DTAEDSIDVE-----------------------VLKAFLAQHYIDKFIPGSLIVGTEFDD 337 A +DVE +L+AF+AQHY+D+F+P L+V Sbjct: 308 -AAIVGVDVEADVPEGAETQPEPARDPERMARDILEAFVAQHYLDQFVPPVLVVSHPIRA 366 Query: 338 PALMMALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIALARLLSEQGSQQARTRALADV 397 L+ AL Q G R+++ QPQG RR WLEMA KGAE++LAR LSEQGSQQARTRALA+ Sbjct: 367 AGLIEALAAQAGRRVSVVRQPQGARRAWLEMAEKGAELSLARRLSEQGSQQARTRALAET 426 Query: 398 LELERDDLDELRAECFDISHTQGEATQASCVVFHHHAMQNGEYRRYNINDITPGDDYAAM 457 + ++ +DL LR ECFDISHT GEATQASCVVFH HAMQNGEYRRYNI DI PGDDYAAM Sbjct: 427 IGVDLEDLAALRVECFDISHTAGEATQASCVVFHSHAMQNGEYRRYNIQDIIPGDDYAAM 486 Query: 458 RQVLTRRYEKV----ANGEGVRPDIVLIDGGKGQVEMARQVLTELGLDISLIVGVAKGEG 513 RQVLTRRY+KV A P +VLIDGGKGQVE+ARQV ELGLDI L+VGVAKGEG Sbjct: 487 RQVLTRRYQKVVEQAAEDAPDMPRVVLIDGGKGQVEVARQVFEELGLDIGLLVGVAKGEG 546 Query: 514 RKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHRFAITGMRAKRAKARQSSRLEEI 573 RKVGLETLVFADGR ELG+ SAALML+AQIRDEAHRFAITGMRAKRAKAR +SRLEEI Sbjct: 547 RKVGLETLVFADGRPSLELGQGSAALMLVAQIRDEAHRFAITGMRAKRAKARNTSRLEEI 606 Query: 574 EGIGAKRRQRLLVRFGGLRGVADASVDDLASVEGISRQLAEEIYRQLH 621 EGIGAKRRQRLL RFGGLRGV ASV++LA+VEGIS+ LAEEIYRQLH Sbjct: 607 EGIGAKRRQRLLARFGGLRGVMAASVEELATVEGISQTLAEEIYRQLH 654 >NMA1540 [L] COG0322 Nuclease subunit of the excinuclease complex NmA Neisseria meningitidis Z2491 Length = 628 Score = 631 bits (1627), Expect = e-180, Method: Compositional matrix adjust. Identities = 326/610 (53%), Positives = 417/610 (68%), Gaps = 17/610 (2%) Query: 20 VARLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTV 79 + LP LPGVYR+FD VLYVGKA +LK+RVS YFQK SPRIA+MV+++ +ETT+ Sbjct: 28 LKNLPKLPGVYRFFDEGGKVLYVGKAVNLKRRVSGYFQKNDHSPRIALMVKQVHHIETTI 87 Query: 80 TRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAFPRMAYYRGAVDKRNQYFG 139 TRSEAEAL+LENN IK L P++NILFRDDKSYPYL ++GH +P+MAYYRG + K NQYFG Sbjct: 88 TRSEAEALILENNFIKALSPKYNILFRDDKSYPYLMLSGHQYPQMAYYRGTLKKPNQYFG 147 Query: 140 PFPNAGAVKESIQILQKVFLLRTCEDTVFSNRTRPCLLHQIHRCSGPCVNLVSREDYAID 199 P+PN+ AV++SIQILQKVF+LRTCED+VF +R RPCLL+QI RC+ PCV +S EDY Sbjct: 148 PYPNSNAVRDSIQILQKVFMLRTCEDSVFEHRDRPCLLYQIKRCTAPCVGHISEEDYRDS 207 Query: 200 VENASKFLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQ---SMETV 256 V A+ FL G+ E+ L+ KM AA+L+FE+AA RDQI +L + Q S Sbjct: 208 VRQAATFLNGKTDELTRTLQHKMQTAAANLQFEEAARYRDQIQALGIMQSNQFIDSKNPN 267 Query: 257 SDADIDIIAVVVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIDVEVLKAFL 316 + DID++A+ V G CV+ +RGGRH+GD+++FP +D +D + AF+ Sbjct: 268 NPNDIDLLALAVSDGLVCVHWVSIRGGRHVGDKSFFPDTKNDPEPNGQDYAE-----AFV 322 Query: 317 AQHYIDKFIPGSLIVGTEFDDPALMMALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIA 376 AQHY+ K P +I D AL AL + G ++ + G+R+ WL+MA + A++A Sbjct: 323 AQHYLGKSKPDIIINNFPVPD-ALKEALEGEHGKQMQFVTKTIGERKVWLKMAEQNAQMA 381 Query: 377 LARLLSEQGSQQARTRALADVLELERDDLDELRAECFDISHTQGEATQASCVVFHHHAMQ 436 +A+ +Q +QQ R LA +L ++ D L+ R ECFDISHTQGEAT ASCVV+ +Q Sbjct: 382 IAQRRLQQSNQQHRIDELAKILGMDSDGLN--RLECFDISHTQGEATIASCVVYDEQNIQ 439 Query: 437 NGEYRRYNINDITPGDDYAAMRQVLTRRYEKV----ANGEGVR-PDIVLIDGGKGQVEMA 491 +YRRYNI PGDDYAAMR+VLTRRY K+ ANGE V+ PD VLIDGGKGQ+ +A Sbjct: 440 PSQYRRYNITTAKPGDDYAAMREVLTRRYGKMQEAEANGETVKWPDAVLIDGGKGQIGIA 499 Query: 492 RQVLTELGLDISLIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHR 551 V ELGL I L VG+AKG RK G+E L+ L S AL L+ +RDE+HR Sbjct: 500 VSVWEELGLHIPL-VGIAKGPERKAGMEELILPFTGEVFRLPPNSPALHLLQTVRDESHR 558 Query: 552 FAITGMRAKRAKARQSSRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDDLASVEGISRQ 611 FAITG R KR KAR +S L +I G+G+KRRQ LL RFGGLRGV AS +DL VEGIS+ Sbjct: 559 FAITGHRKKRDKARVTSSLSDIPGVGSKRRQALLTRFGGLRGVIAASREDLEKVEGISKA 618 Query: 612 LAEEIYRQLH 621 LAE IY LH Sbjct: 619 LAETIYEHLH 628 >NMB1326 [L] COG0322 Nuclease subunit of the excinuclease complex Nme Neisseria meningitidis MC58 Length = 617 Score = 618 bits (1593), Expect = e-176, Method: Compositional matrix adjust. Identities = 324/610 (53%), Positives = 418/610 (68%), Gaps = 17/610 (2%) Query: 20 VARLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTV 79 + LP+LPGVYR+F+ NVLYVGKA +LK+RVS YFQK SPRIA+MV+++ +ETT+ Sbjct: 17 LKNLPNLPGVYRFFNESGNVLYVGKAVNLKRRVSGYFQKNDHSPRIALMVKQVHHIETTI 76 Query: 80 TRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAFPRMAYYRGAVDKRNQYFG 139 TRSE+EAL+LENN IK L P++NILFRDDKSYPYL ++GH +P+MAYYRG + K NQYFG Sbjct: 77 TRSESEALILENNFIKALSPKYNILFRDDKSYPYLMLSGHQYPQMAYYRGTLKKPNQYFG 136 Query: 140 PFPNAGAVKESIQILQKVFLLRTCEDTVFSNRTRPCLLHQIHRCSGPCVNLVSREDYAID 199 P+PN+ AV++SIQ+LQKVF+LRTCED+VF +R RPCLL+QI RC+ PCV +S EDY Sbjct: 137 PYPNSNAVRDSIQVLQKVFMLRTCEDSVFEHRDRPCLLYQIKRCTAPCVGHISEEDYRDS 196 Query: 200 VENASKFLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQ---SMETV 256 V A+ FL G+ E+ L+ KM AA+L+FE+AA RDQI +L + Q S Sbjct: 197 VREAATFLNGKTDELTRTLQHKMQTAAANLQFEEAARYRDQIQALGIMQSNQFIDSKNPN 256 Query: 257 SDADIDIIAVVVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIDVEVLKAFL 316 + DID++A+ V G CV+ +RGGRH+GD+++FP +D +D + AF+ Sbjct: 257 NPNDIDLLALAVSDGLVCVHWVSIRGGRHVGDKSFFPDTKNDPEPNGQDYAE-----AFV 311 Query: 317 AQHYIDKFIPGSLIVGTEFDDPALMMALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIA 376 AQHY+ K P +I D AL AL + G ++ + G+R+ L+MA + A++A Sbjct: 312 AQHYLGKSKPDIIISNFPVPD-ALKEALEGEHGKQMQFVTKTIGERKVRLKMAEQNAQMA 370 Query: 377 LARLLSEQGSQQARTRALADVLELERDDLDELRAECFDISHTQGEATQASCVVFHHHAMQ 436 +A+ +Q SQQ R LA +L ++ D L+ R ECFDISHTQGEAT ASCVV+ +Q Sbjct: 371 IAQRRLQQSSQQHRIDELAKILGMDSDGLN--RLECFDISHTQGEATIASCVVYDEQNIQ 428 Query: 437 NGEYRRYNINDITPGDDYAAMRQVLTRRYEKV----ANGEGVR-PDIVLIDGGKGQVEMA 491 +YRRYNI PGDDYAAMR+VLTRRY K+ ANGE V+ PD VLIDGGKGQ+ +A Sbjct: 429 PSQYRRYNITTAKPGDDYAAMREVLTRRYGKMQEAEANGETVKWPDAVLIDGGKGQIGVA 488 Query: 492 RQVLTELGLDISLIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHR 551 V ELGL I L VG+AKG RK G+E L+ L S AL L+ +RDE+HR Sbjct: 489 VSVWEELGLHIPL-VGIAKGPERKAGMEELILPFTGEVFRLPPNSPALHLLQTVRDESHR 547 Query: 552 FAITGMRAKRAKARQSSRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDDLASVEGISRQ 611 FAITG R KR KAR +S L +I G+G+KRRQ LL RFGGLRGV AS +DL VEGIS+ Sbjct: 548 FAITGHRKKRDKARVTSSLSDIPGVGSKRRQALLTRFGGLRGVIAASREDLEKVEGISKA 607 Query: 612 LAEEIYRQLH 621 LAE IY LH Sbjct: 608 LAETIYNHLH 617 >PA2585 [L] COG0322 Nuclease subunit of the excinuclease complex Pae Pseudomonas aeruginosa Length = 608 Score = 574 bits (1480), Expect = e-163, Method: Compositional matrix adjust. Identities = 302/600 (50%), Positives = 407/600 (67%), Gaps = 16/600 (2%) Query: 27 PGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTVTRSEAEA 86 PGVYR FDAE +LYVGKA+ LKKR++SYF+K+ +P+ A +V RIA++ETT+T +E EA Sbjct: 18 PGVYRMFDAEAKLLYVGKAKSLKKRLASYFRKSGLAPKTAALVARIAQVETTITANETEA 77 Query: 87 LLLENNLIKTLRPRFNILFRDDKSYPYLKITGH-AFPRMAYYRGAVDKRNQYFGPFPNAG 145 LLLE LIK RP +NIL RDDKSYP++ ++ +PR++ +RGA ++ +YFGP+P+AG Sbjct: 78 LLLEQTLIKEWRPPYNILLRDDKSYPFVFLSSEDEYPRLSLHRGAKKRKGRYFGPYPSAG 137 Query: 146 AVKESIQILQKVFLLRTCEDTVFSNRTRPCLLHQIHRCSGPCVNLVSREDYAIDVENASK 205 A++ES+ +LQK FL+R CED+ F NRTRPCL +QI RC GPCV LVS E+YA DV ++ Sbjct: 138 AIRESLNLLQKAFLVRQCEDSYFRNRTRPCLQYQIKRCKGPCVGLVSPEEYAEDVRHSVM 197 Query: 206 FLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETVSDADIDIIA 265 FL GR + + + L M A L FE+AA +RDQ+ L V QQSME + D+DI+A Sbjct: 198 FLEGRSNALADELNVGMEQAAMRLDFEKAAELRDQVAILRRVQDQQSMEG-GNGDVDIVA 256 Query: 266 VVVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIDVEVLKAFLAQHYI---D 322 +V G ACV+L VRGGR LG + +FP E+ + EVL AFL Q+Y+ + Sbjct: 257 AIVTPGGACVHLISVRGGRVLGSKNFFP------QVAIEEEVG-EVLLAFLGQYYLSHQE 309 Query: 323 KFIPGSLIVGTEFDD-PALMMALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIALARLL 381 + +P LIV +D P L+ A+ E G + ++++ +G R +W ++A AE AL L Sbjct: 310 RDLPAELIVNVTHEDFPVLVSAIAEARGRELEISYRVRGTRARWQQLAVTNAEQALGARL 369 Query: 382 SEQGSQQARTRALADVLELERDDLDELRAECFDISHTQGEATQASCVVFHHHAMQNGEYR 441 + + AR ALA+ L+L R ECFDISH+ GEAT ASCVVF +YR Sbjct: 370 ANRQHVAARFEALAEALDLAEPPQ---RLECFDISHSSGEATVASCVVFGPEGPLKSDYR 426 Query: 442 RYNINDITPGDDYAAMRQVLTRRYEKVANGEGVRPDIVLIDGGKGQVEMARQVLTELGLD 501 RYNI +T GDDYAAM Q LTRR+ ++ +GEG PDI+L+DGGKGQ+ MA++VL EL + Sbjct: 427 RYNIEGVTAGDDYAAMHQALTRRFSRLKDGEGKMPDILLVDGGKGQLAMAQEVLQELAVA 486 Query: 502 ISLIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHRFAITGMRAKR 561 +++GVAKG RK GLETL D L +S AL LI QIRDEAHRFAITG RA+R Sbjct: 487 GLILLGVAKGVTRKPGLETLYLNDASHEFTLPADSPALHLIQQIRDEAHRFAITGHRARR 546 Query: 562 AKARQSSRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDDLASVEGISRQLAEEIYRQLH 621 KAR++S LE++ G+G KRR+ LL FGGL+ ++ AS+D+LA GIS++LAE+IY LH Sbjct: 547 GKARRTSTLEDVPGVGPKRRRDLLKHFGGLQELSRASIDELAKAPGISKKLAEQIYAVLH 606 >XF2311 [L] COG0322 Nuclease subunit of the excinuclease complex Xfa Xylella fastidiosa 9a5c Length = 627 Score = 529 bits (1363), Expect = e-150, Method: Compositional matrix adjust. Identities = 280/606 (46%), Positives = 392/606 (64%), Gaps = 19/606 (3%) Query: 21 ARLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTVT 80 A L PGVY + A+D +LYVGKA L+KRV+SYF T + R+ M+ ++ R++ T+T Sbjct: 22 AHLSMAPGVYCMYAADDTLLYVGKAGALRKRVASYFNGTPKNTRLTAMLAQVVRMDVTIT 81 Query: 81 RSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAFPRMAYYRGAVDKRNQYFGP 140 R+EAEALLLEN LIK+L PR+N+L RDDKSYPY+ +T A+PR+A +RG +YFGP Sbjct: 82 RNEAEALLLENQLIKSLAPRYNVLLRDDKSYPYVLLTREAWPRIALHRGPQIVPGRYFGP 141 Query: 141 FPNAGAVKESIQILQKVFLLRTCEDTVFSNRTRPCLLHQIHRCSGPCVNLVSREDYAIDV 200 +P AV++ + ++ K+F LR+CED+VF NR+RPCL +QI RCS PCVN+V+ ++Y V Sbjct: 142 YPGVTAVRDMLNLIHKLFKLRSCEDSVFRNRSRPCLQYQIGRCSAPCVNVVTHDNYTEAV 201 Query: 201 ENASKFLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETVSDAD 260 + FL G+ + E L Q M + L+FEQAA +RD + SL S+ ++Q ++ + AD Sbjct: 202 RRVTLFLEGKSDLLAEELIQAMQVASEHLEFEQAARLRDLLTSLRSMQNRQYVDGRA-AD 260 Query: 261 IDIIAVVVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIDVEVLKAFLAQHY 320 +D++A G ACV L R GR+LG R +FP T + E+L AF++Q+Y Sbjct: 261 LDVLACAALSGHACVLLLSFRDGRNLGTRMFFP-------KTNGEERTAEILSAFVSQYY 313 Query: 321 IDKFIPGSLIVGTEFDDPALM-MALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIALAR 379 + P +++ E D L+ A H+I+L + +G+R ++E+A + A++AL+ Sbjct: 314 AEYPPPPEILLDQEIPDHTLLEAAFSRSSAHKISLRWNVRGERAGYVELAVRNAQVALST 373 Query: 380 LLSEQGSQQARTRALADVLELERDDLDELRAECFDISHTQGEATQASCVVFHHHAMQNGE 439 L+ Q +Q+ R+ A+ +L LE R ECFDISHT GEAT ASCVVF + Sbjct: 374 ELTSQRAQRVRSEAVRQLLGLEEPI---KRVECFDISHTMGEATVASCVVFDAVGPVRSQ 430 Query: 440 YRRYNINDITPGDDYAAMRQVLTRRYEKVA--NGEGVRPDIVLIDGGKGQVEMARQVLTE 497 YRRYNI ITPGDDYAAMRQ + RR+ + + +G RPD++ IDGG GQ+ A+ L Sbjct: 431 YRRYNITGITPGDDYAAMRQAIERRFRRAVEEDKQGERPDVLFIDGGAGQLAQAKMALNA 490 Query: 498 LGLDISLIVGVAKGEGRKVGLETLVFADGRAPKEL--GKESAALMLIAQIRDEAHRFAIT 555 +G++ L+VGV+KGE R+ G ETL+ DG +EL G S AL I Q+RDEAHRFAIT Sbjct: 491 VGVESVLLVGVSKGEERRAGHETLIMLDG---QELHPGAASPALQFIQQVRDEAHRFAIT 547 Query: 556 GMRAKRAKARQSSRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDDLASVEGISRQLAEE 615 G RA+R K R +S+LE+I GIG++RR LL FGGL GV A ++A VEGIS LA + Sbjct: 548 GHRARRQKTRMTSKLEDIPGIGSRRRANLLKHFGGLAGVKAAGQTEIARVEGISTALAAK 607 Query: 616 IYRQLH 621 IY LH Sbjct: 608 IYASLH 613 >VC1214 [L] COG0322 Nuclease subunit of the excinuclease complex Vch Vibrio cholerae Length = 610 Score = 520 bits (1338), Expect = e-147, Method: Compositional matrix adjust. Identities = 273/604 (45%), Positives = 391/604 (64%), Gaps = 23/604 (3%) Query: 27 PGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTVTRSEAEA 86 PGVYR ++AE V+YVGKA+DLKKR++SYF+K L S + +V IA+++ TVT +E EA Sbjct: 18 PGVYRMYNAEAEVIYVGKAKDLKKRLTSYFRKNLDSEKTKALVSNIAKIDVTVTHTETEA 77 Query: 87 LLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAFPRMAYYRGAVDKRNQYFGPFPNAGA 146 L+LE+N IK P++N+L RDDKSYPY+ ++ H PR++ +RGA +R +YFGP+P++GA Sbjct: 78 LILEHNYIKQYLPKYNVLLRDDKSYPYIFLSAHKHPRLSSHRGAKKRRGEYFGPYPDSGA 137 Query: 147 VKESIQILQKVFLLRTCEDTVFSNRTRPCLLHQIHRCSGPCVN-LVSREDYAIDVENASK 205 V+E++ ++QK+F +R CEDTV+SNRTRPCL++QI RC+GPCV L+S + Y V Sbjct: 138 VRETLHLIQKIFPVRQCEDTVYSNRTRPCLMYQIGRCAGPCVKGLISDQGYQEIVHYLRL 197 Query: 206 FLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETVSDADIDIIA 265 FL+G+ ++V+ L +KM + +L+FE AA RDQI ++ V QQ + S D+D++ Sbjct: 198 FLQGKDNQVLSILVEKMEQASRELRFEDAAKARDQIQAIRRVQEQQFVSDDSLEDLDVLG 257 Query: 266 VVVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIDVEVLKAFLAQHYID--- 322 + G AC+++ M+R G+ LG R++FP D+ VEV ++FL+Q+Y+ Sbjct: 258 FAQENGIACIHILMIRQGKVLGSRSHFP-------KIPSDTSQVEVFESFLSQYYLSHSE 310 Query: 323 -KFIPGSLIV--GTEFDDPALMMALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIALAR 379 + IP +I+ G + AL +A+ E G ++T P G R ++L++A A A+ Sbjct: 311 ARSIPARIILNRGLTEETEALQIAISELAGRKVTFHVNPTGTRGRYLKLANTNALTAITT 370 Query: 380 LLSEQGSQQARTRALADVLELERDDLDELRAECFDISHTQGEATQASCVVFHHHAMQNGE 439 ++ + + R +AL + EL D + R ECFDISHT GE+T ASCVVF+ E Sbjct: 371 KMNHKMTISQRFKALQE--ELGMDAIT--RMECFDISHTMGESTMASCVVFNQEGPLKQE 426 Query: 440 YRRYNINDITPGDDYAAMRQVLTRRYEKVANGEGVRPDIVLIDGGKGQVEMARQVLTELG 499 YRRYNI IT GDDYAAM QVL RRY K + + PDI+ IDGGKGQ+ A ++++ Sbjct: 427 YRRYNITGITGGDDYAAMAQVLERRYSKQLDSSKI-PDIIFIDGGKGQLNRAYEIISSCW 485 Query: 500 LD---ISLIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHRFAITG 556 D I+G+AKG RK GLETL+ DG L ++ AL LI IRDE+H AI G Sbjct: 486 QDWPKYPKIIGIAKGVTRKPGLETLITIDGDE-FHLPSDAPALHLIQHIRDESHNHAIAG 544 Query: 557 MRAKRAKARQSSRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDDLASVEGISRQLAEEI 616 RA+R K R++S LE IEG+G KRRQ LL GG++ + ASV+++A V GIS LAE I Sbjct: 545 HRAQRGKTRRTSTLEGIEGVGPKRRQALLKYLGGMQELKRASVEEIAKVPGISHALAENI 604 Query: 617 YRQL 620 Y+ L Sbjct: 605 YQAL 608 >STM1946 [L] COG0322 Nuclease subunit of the excinuclease complex Sty Salmonella typhimurium LT2 Length = 610 Score = 520 bits (1338), Expect = e-147, Method: Compositional matrix adjust. Identities = 289/617 (46%), Positives = 389/617 (63%), Gaps = 26/617 (4%) Query: 14 EAVLETVARLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIA 73 +A L+TV PGVYR +DA V+YVGKA+DLKKR+SSYF+ L S + +V +I Sbjct: 8 KAFLKTVT---SQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQ 64 Query: 74 RLETTVTRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAFPRMAYYRGAVDK 133 ++ TVT +E EALLLE+N IK +PR+N+L RDDKSYP++ ++G PR+A +RGA Sbjct: 65 HIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHA 124 Query: 134 RNQYFGPFPNAGAVKESIQILQKVFLLRTCEDTVFSNRTRPCLLHQIHRCSGPCV-NLVS 192 + +YFGPFPN AV+E++ +LQK+F +R CE++V+ NR+RPCL +QI RC GPCV LVS Sbjct: 125 KGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYRNRSRPCLQYQIGRCLGPCVAGLVS 184 Query: 193 REDYAIDVENASKFLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQS 252 E+YA VE FL G+ +V+ L +M + DL FE+AA +RDQI ++ V +Q Sbjct: 185 EEEYAQQVEYVRLFLSGKDDQVLTQLIARMEKASQDLAFEEAARIRDQIQAVRRVTEKQF 244 Query: 253 METVSDADIDIIAVVVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIDVEVL 312 + D D+D+I V G ACV++ +R G+ LG R+YFP V + EV+ Sbjct: 245 VSNAGD-DLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPK-VPGGTELG------EVV 296 Query: 313 KAFLAQHYID----KFIPGSLIVGTEFDDPALMM-ALMEQCGHRITLTFQPQGQRRQWLE 367 + F+ Q Y+ + +PG +++ D L+ +L E G RI + +P+G R ++L+ Sbjct: 297 ETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLSELAGRRIHVQTKPRGDRARYLK 356 Query: 368 MAAKGAEIALARLLSEQGSQQARTRALADVLELERDDLDELRAECFDISHTQGEATQASC 427 +A A AL LS+Q + R ALA VL+L R ECFDISHT GE T ASC Sbjct: 357 LARTNAATALITKLSQQSTITQRLSALAAVLKLPAIK----RMECFDISHTMGEQTVASC 412 Query: 428 VVFHHHAMQNGEYRRYNINDITPGDDYAAMRQVLTRRYEKVANGEGVRPDIVLIDGGKGQ 487 VVF + EYRRYNI ITPGDDYAAM QVL RRY K A E PD++LIDGGKGQ Sbjct: 413 VVFDANGPLRAEYRRYNIAGITPGDDYAAMNQVLRRRYGK-AIEESKIPDVILIDGGKGQ 471 Query: 488 VEMARQVLTELGLDI----SLIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIA 543 + A+ V EL + L++GVAKG RK GLETL F L +S AL +I Sbjct: 472 LAQAKAVFAELDVPWDKHRPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQ 531 Query: 544 QIRDEAHRFAITGMRAKRAKARQSSRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDDLA 603 IRDE+H AI G R KRAK + +S LE IEG+G KRRQ LL GGL+G+ +ASV+++A Sbjct: 532 HIRDESHDHAIGGHRKKRAKVKNTSTLETIEGVGPKRRQMLLKYMGGLQGLRNASVEEIA 591 Query: 604 SVEGISRQLAEEIYRQL 620 V GIS+ LAE+I+ L Sbjct: 592 KVPGISQGLAEKIFWSL 608 >uvrC [L] COG0322 Nuclease subunit of the excinuclease complex Eco Escherichia coli K12 Length = 588 Score = 514 bits (1324), Expect = e-145, Method: Compositional matrix adjust. Identities = 278/600 (46%), Positives = 384/600 (64%), Gaps = 27/600 (4%) Query: 33 FDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTVTRSEAEALLLENN 92 +DA V+YVGKA+DLKKR+SSYF+ L S + +V +I +++ TVT +E EALLLE+N Sbjct: 2 YDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHN 61 Query: 93 LIKTLRPRFNILFRDDKSYPYLKITGHAFPRMAYYRGAVDKRNQYFGPFPNAGAVKESIQ 152 IK +PR+N+L RDDKSYP++ ++G PR+A +RGA + +YFGPFPN AV+E++ Sbjct: 62 YIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLA 121 Query: 153 ILQKVFLLRTCEDTVFSNRTRPCLLHQIHRCSGPCV-NLVSREDYAIDVENASKFLRGRQ 211 +LQK+F +R CE++V+ NR+RPCL +QI RC GPCV LVS E+YA VE FL G+ Sbjct: 122 LLQKIFPIRQCENSVYRNRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKD 181 Query: 212 SEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETVSDADIDIIAVVVQGG 271 +V+ L +M + +L+FE+AA +RDQI ++ V +Q + D D+D+I V G Sbjct: 182 DQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVTEKQFVSNTGD-DLDVIGVAFDAG 240 Query: 272 RACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIDVEVLKAFLAQHYID----KFIPG 327 ACV++ +R G+ LG R+YFP V + + EV++ F+ Q Y+ + +PG Sbjct: 241 MACVHVLFIRQGKVLGSRSYFPK-VPGGTELS------EVVETFVGQFYLQGSQMRTLPG 293 Query: 328 SLIVGTEFDDPALMM-ALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIALARLLSEQGS 386 +++ D L+ +L E G +I + +P+G R ++L++A A AL LS+Q + Sbjct: 294 EILLDFNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQST 353 Query: 387 QQARTRALADVLELERDDLDELRAECFDISHTQGEATQASCVVFHHHAMQNGEYRRYNIN 446 R ALA VL+L + R ECFDISHT GE T ASCVVF + EYRRYNI Sbjct: 354 VHQRLTALASVLKLP----EVKRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNIT 409 Query: 447 DITPGDDYAAMRQVLTRRYEKVANGEGVRPDIVLIDGGKGQVEMARQVLTELGLDIS--- 503 ITPGDDYAAM QVL RRY K + + PD++LIDGGKGQ+ A+ V E LD+S Sbjct: 410 GITPGDDYAAMNQVLRRRYGKAIDDSKI-PDVILIDGGKGQLAQAKNVFAE--LDVSWDK 466 Query: 504 ---LIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHRFAITGMRAK 560 L++GVAKG RK GLETL F L +S AL +I IRDE+H AI G R K Sbjct: 467 NHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKK 526 Query: 561 RAKARQSSRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDDLASVEGISRQLAEEIYRQL 620 RAK + +S LE IEG+G KRRQ LL GGL+G+ +ASV+++A V GIS+ LAE+I+ L Sbjct: 527 RAKVKNTSSLETIEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSL 586 >ZuvrC [L] COG0322 Nuclease subunit of the excinuclease complex EcZ Escherichia coli O157:H7 EDL933 Length = 588 Score = 514 bits (1324), Expect = e-145, Method: Compositional matrix adjust. Identities = 278/600 (46%), Positives = 384/600 (64%), Gaps = 27/600 (4%) Query: 33 FDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTVTRSEAEALLLENN 92 +DA V+YVGKA+DLKKR+SSYF+ L S + +V +I +++ TVT +E EALLLE+N Sbjct: 2 YDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHN 61 Query: 93 LIKTLRPRFNILFRDDKSYPYLKITGHAFPRMAYYRGAVDKRNQYFGPFPNAGAVKESIQ 152 IK +PR+N+L RDDKSYP++ ++G PR+A +RGA + +YFGPFPN AV+E++ Sbjct: 62 YIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLA 121 Query: 153 ILQKVFLLRTCEDTVFSNRTRPCLLHQIHRCSGPCV-NLVSREDYAIDVENASKFLRGRQ 211 +LQK+F +R CE++V+ NR+RPCL +QI RC GPCV LVS E+YA VE FL G+ Sbjct: 122 LLQKIFPIRQCENSVYRNRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKD 181 Query: 212 SEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETVSDADIDIIAVVVQGG 271 +V+ L +M + +L+FE+AA +RDQI ++ V +Q + D D+D+I V G Sbjct: 182 DQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVTEKQFVSNTGD-DLDVIGVAFDAG 240 Query: 272 RACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIDVEVLKAFLAQHYID----KFIPG 327 ACV++ +R G+ LG R+YFP V + + EV++ F+ Q Y+ + +PG Sbjct: 241 MACVHVLFIRQGKVLGSRSYFPK-VPGGTELS------EVVETFVGQFYLQGSQMRTLPG 293 Query: 328 SLIVGTEFDDPALMM-ALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIALARLLSEQGS 386 +++ D L+ +L E G +I + +P+G R ++L++A A AL LS+Q + Sbjct: 294 EILLDFNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQST 353 Query: 387 QQARTRALADVLELERDDLDELRAECFDISHTQGEATQASCVVFHHHAMQNGEYRRYNIN 446 R ALA VL+L + R ECFDISHT GE T ASCVVF + EYRRYNI Sbjct: 354 VHQRLTALASVLKLP----EVKRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNIT 409 Query: 447 DITPGDDYAAMRQVLTRRYEKVANGEGVRPDIVLIDGGKGQVEMARQVLTELGLDIS--- 503 ITPGDDYAAM QVL RRY K + + PD++LIDGGKGQ+ A+ V E LD+S Sbjct: 410 GITPGDDYAAMNQVLRRRYGKAIDDSKI-PDVILIDGGKGQLAQAKNVFAE--LDVSWDK 466 Query: 504 ---LIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHRFAITGMRAK 560 L++GVAKG RK GLETL F L +S AL +I IRDE+H AI G R K Sbjct: 467 NHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKK 526 Query: 561 RAKARQSSRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDDLASVEGISRQLAEEIYRQL 620 RAK + +S LE IEG+G KRRQ LL GGL+G+ +ASV+++A V GIS+ LAE+I+ L Sbjct: 527 RAKVKNTSSLETIEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSL 586 >ECs2651 [L] COG0322 Nuclease subunit of the excinuclease complex Ecs Escherichia coli O157:H7 Length = 588 Score = 514 bits (1324), Expect = e-145, Method: Compositional matrix adjust. Identities = 278/600 (46%), Positives = 384/600 (64%), Gaps = 27/600 (4%) Query: 33 FDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTVTRSEAEALLLENN 92 +DA V+YVGKA+DLKKR+SSYF+ L S + +V +I +++ TVT +E EALLLE+N Sbjct: 2 YDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHN 61 Query: 93 LIKTLRPRFNILFRDDKSYPYLKITGHAFPRMAYYRGAVDKRNQYFGPFPNAGAVKESIQ 152 IK +PR+N+L RDDKSYP++ ++G PR+A +RGA + +YFGPFPN AV+E++ Sbjct: 62 YIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLA 121 Query: 153 ILQKVFLLRTCEDTVFSNRTRPCLLHQIHRCSGPCV-NLVSREDYAIDVENASKFLRGRQ 211 +LQK+F +R CE++V+ NR+RPCL +QI RC GPCV LVS E+YA VE FL G+ Sbjct: 122 LLQKIFPIRQCENSVYRNRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKD 181 Query: 212 SEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETVSDADIDIIAVVVQGG 271 +V+ L +M + +L+FE+AA +RDQI ++ V +Q + D D+D+I V G Sbjct: 182 DQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVTEKQFVSNTGD-DLDVIGVAFDAG 240 Query: 272 RACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIDVEVLKAFLAQHYID----KFIPG 327 ACV++ +R G+ LG R+YFP V + + EV++ F+ Q Y+ + +PG Sbjct: 241 MACVHVLFIRQGKVLGSRSYFPK-VPGGTELS------EVVETFVGQFYLQGSQMRTLPG 293 Query: 328 SLIVGTEFDDPALMM-ALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIALARLLSEQGS 386 +++ D L+ +L E G +I + +P+G R ++L++A A AL LS+Q + Sbjct: 294 EILLDFNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQST 353 Query: 387 QQARTRALADVLELERDDLDELRAECFDISHTQGEATQASCVVFHHHAMQNGEYRRYNIN 446 R ALA VL+L + R ECFDISHT GE T ASCVVF + EYRRYNI Sbjct: 354 VHQRLTALASVLKLP----EVKRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNIT 409 Query: 447 DITPGDDYAAMRQVLTRRYEKVANGEGVRPDIVLIDGGKGQVEMARQVLTELGLDIS--- 503 ITPGDDYAAM QVL RRY K + + PD++LIDGGKGQ+ A+ V E LD+S Sbjct: 410 GITPGDDYAAMNQVLRRRYGKAIDDSKI-PDVILIDGGKGQLAQAKNVFAE--LDVSWDK 466 Query: 504 ---LIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHRFAITGMRAK 560 L++GVAKG RK GLETL F L +S AL +I IRDE+H AI G R K Sbjct: 467 NHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKK 526 Query: 561 RAKARQSSRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDDLASVEGISRQLAEEIYRQL 620 RAK + +S LE IEG+G KRRQ LL GGL+G+ +ASV+++A V GIS+ LAE+I+ L Sbjct: 527 RAKVKNTSSLETIEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSL 586