BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0082.p (343 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1044 [OU] COG0616 Periplasmic serine proteases (ClpP class) R... 393 e-109 PA2973 [OU] COG0616 Periplasmic serine proteases (ClpP class) Pa... 283 3e-76 NMB2127 [OU] COG0616 Periplasmic serine proteases (ClpP class) N... 239 6e-63 NMA0305 [OU] COG0616 Periplasmic serine proteases (ClpP class) N... 239 6e-63 AGc1130 [OU] COG0616 Periplasmic serine proteases (ClpP class) A... 178 1e-44 SMc00857 [OU] COG0616 Periplasmic serine proteases (ClpP class) ... 175 1e-43 mll7424 [OU] COG0616 Periplasmic serine proteases (ClpP class) M... 174 2e-43 BMEI1535_2 [OU] COG0616 Periplasmic serine proteases (ClpP class... 169 6e-42 RC0545 [OU] COG0616 Periplasmic serine proteases (ClpP class) Rc... 146 5e-35 RP398 [OU] COG0616 Periplasmic serine proteases (ClpP class) Rpr... 143 5e-34 >RSc1044 [OU] COG0616 Periplasmic serine proteases (ClpP class) Rso Ralstonia solanacearum Length = 378 Score = 393 bits (1010), Expect = e-109, Method: Compositional matrix adjust. Identities = 193/311 (62%), Positives = 240/311 (77%), Gaps = 5/311 (1%) Query: 34 SGWERDVLEKLALFAVKEQRARRRWGVFFRIALLAVVVLGVWMAFTFNRIENEPL--GPH 91 +GWERDVLE++ L A++EQRA RRW +FFR L ++ + + F E E + G H Sbjct: 67 AGWERDVLERVLLAAIREQRAARRWRIFFRFVTLGIIG---GLLYLFASFEGETVSSGRH 123 Query: 92 TALVEIKGAIDSEGQGSAGVVIPALDKAFAADDSVGVILKINSPGGSPVQAGMINDEITR 151 TALV + G I + SA + +L+ AFA D++ GVILKINSPGGSPVQAGMIND+I R Sbjct: 124 TALVTLDGEIAANTNASADNINASLEAAFADDNTAGVILKINSPGGSPVQAGMINDDIRR 183 Query: 152 LRKQYPKKPIYVVVEEVCASGGYYIAAAADKIFVNKASLVGSVGVLMDGFGFTGLMDKLG 211 LR +Y P+YVVVEE+CASGGYY+AAAADKI+V+KAS+VGS+GVLMDGFGFTGLMDKLG Sbjct: 184 LRAKYKNIPLYVVVEEMCASGGYYVAAAADKIYVDKASIVGSIGVLMDGFGFTGLMDKLG 243 Query: 212 VERRLLTAGENKSFLDPFSPQSPKQREYAQSMLQEIHQQFIEVVRQGRGARLKETPDTFS 271 VERRLLTAG NK LDPFSP +P+QR++AQ+ML E+HQQFI+VV+QGRG+RLK+ P FS Sbjct: 244 VERRLLTAGTNKGMLDPFSPVAPQQRQFAQAMLDEVHQQFIDVVKQGRGSRLKDDPQLFS 303 Query: 272 GLVWTGSKAVELGLADGFGTVDSVARDEIKAEDVVDYTQTENLSERVLKKFGVAFGAGFA 331 GL WTG+KAV+LGLADG G D VAR+ IKA D+VDYT EN +ERV +KFG A GAG Sbjct: 304 GLFWTGAKAVDLGLADGIGGTDFVARNIIKAPDLVDYTVKENFAERVARKFGTAMGAGAI 363 Query: 332 KTVMSSSLPQL 342 K + ++ +L Sbjct: 364 KALAATGQLKL 374 >PA2973 [OU] COG0616 Periplasmic serine proteases (ClpP class) Pae Pseudomonas aeruginosa Length = 326 Score = 283 bits (725), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 148/301 (49%), Positives = 206/301 (68%), Gaps = 10/301 (3%) Query: 30 DDKKSGWERDVLEKLALFAVKEQRARRRWGVFFRIALLAVVVLGVWMAFT-FNRIENEPL 88 DDK W+ +LEK L V+EQR RRWG+FF+ +L + + V +AF+ F +E Sbjct: 14 DDKS--WK--LLEKAVLAGVQEQRRARRWGIFFK-SLTFIYLFVVLLAFSPFGSLEKSAS 68 Query: 89 --GPHTALVEIKGAIDSEGQGSAGVVIPALDKAFAADDSVGVILKINSPGGSPVQAGMIN 146 G HTAL+E+KG I + SA ++ AL AF + + G++L+INSPGGSPVQ+G I Sbjct: 69 RSGSHTALIEVKGMIADDEPASADNIVTALRAAFKDEGTKGIVLRINSPGGSPVQSGYIY 128 Query: 147 DEITRLRKQYPKKPIYVVVEEVCASGGYYIAAAADKIFVNKASLVGSVGVLMDGFGFTGL 206 DEI RLR ++P +Y V+ ++ ASG YYIA+AAD+I+ +KASLVGS+GV FGF G Sbjct: 129 DEIRRLRGEHPNVKVYAVISDLGASGAYYIASAADQIYADKASLVGSIGVTAASFGFVGT 188 Query: 207 MDKLGVERRLLTAGENKSFLDPFSPQSPKQREYAQSMLQEIHQQFIEVVRQGRGARLK-- 264 M+KLGVERR+ T+GE+KSFLDPF PQ P++ ++ Q +L H+QFI+ V++GRG RLK Sbjct: 189 MEKLGVERRVYTSGEHKSFLDPFQPQKPEETQFWQQVLDTTHKQFIDSVKKGRGDRLKVE 248 Query: 265 ETPDTFSGLVWTGSKAVELGLADGFGTVDSVARDEIKAEDVVDYTQTENLSERVLKKFGV 324 P+ FSGLVW+G +A++LGL DG G VAR+ +K + + DYT E+ +R KKFG Sbjct: 249 GHPELFSGLVWSGEQALQLGLIDGLGNASYVAREVVKEKKIEDYTVQESPFDRFAKKFGA 308 Query: 325 A 325 + Sbjct: 309 S 309 >NMB2127 [OU] COG0616 Periplasmic serine proteases (ClpP class) Nme Neisseria meningitidis MC58 Length = 328 Score = 239 bits (611), Expect = 6e-63, Method: Compositional matrix adjust. Identities = 123/297 (41%), Positives = 188/297 (63%), Gaps = 4/297 (1%) Query: 36 WERDVLEKLALFAVKEQRARRRWGVFFRIALLAVVVLGVWMAFTFNRIENEPLG--PHTA 93 WERD++ ++ L A +++R R W +R ++V + F + + G PHTA Sbjct: 22 WERDIMREVLLSAYQDRRRERMWKNIWRAVSTLILVALIAGIFRKDEAALQLAGNTPHTA 81 Query: 94 LVEIKGAIDSEGQGSAGVVIPALDKAFAADDSVGVILKINSPGGSPVQAGMINDEITRLR 153 +V + G I + + + ++ A+ + ++++ NSPGGSPV + +EI RL+ Sbjct: 82 VVNLYGEIGNGVEDQVKKLKDGMEAAYKNPQAKAIVIRANSPGGSPVVSNTAFEEIRRLK 141 Query: 154 KQYPKKPIYVVVEEVCASGGYYIAAAADKIFVNKASLVGSVGVLMDGFGFTGLMDKLGVE 213 Q+P P+Y+V E++CASG YYIAAAADKI+ + +S+VGS+GV+ F TGLM+K+GV+ Sbjct: 142 AQHPGIPVYLVAEDMCASGCYYIAAAADKIYADPSSIVGSIGVIGSSFDATGLMEKIGVK 201 Query: 214 RRLLTAGENKSFLDPFSPQSPKQREYAQSMLQEIHQQFIEVVRQGRGARLK--ETPDTFS 271 RR+ AG NK DPFSP++P+Q + + ML IH +FI+ V+ GRG RLK + PD FS Sbjct: 202 RRVKIAGSNKGMGDPFSPETPEQSKIWEEMLTGIHGEFIKAVKTGRGGRLKFRQYPDVFS 261 Query: 272 GLVWTGSKAVELGLADGFGTVDSVARDEIKAEDVVDYTQTENLSERVLKKFGVAFGA 328 G V+TG+ A+++GL DG G + SVARD +KA DVVDYT ++ + ++FG A Sbjct: 262 GRVYTGADALKVGLVDGLGNIYSVARDVVKAPDVVDYTPKDDFGRILGRRFGAELKA 318 >NMA0305 [OU] COG0616 Periplasmic serine proteases (ClpP class) NmA Neisseria meningitidis Z2491 Length = 328 Score = 239 bits (610), Expect = 6e-63, Method: Compositional matrix adjust. Identities = 123/297 (41%), Positives = 188/297 (63%), Gaps = 4/297 (1%) Query: 36 WERDVLEKLALFAVKEQRARRRWGVFFRIALLAVVVLGVWMAFTFNRIENEPLG--PHTA 93 WERD++ ++ L A +++R R W +R ++V + F + + G PHTA Sbjct: 22 WERDMMREVLLSAYRDRRRERMWKNIWRAVSTLILVALIAGIFRKDEAALQLAGNTPHTA 81 Query: 94 LVEIKGAIDSEGQGSAGVVIPALDKAFAADDSVGVILKINSPGGSPVQAGMINDEITRLR 153 +V + G I + + + ++ A+ + ++++ NSPGGSPV + +EI RL+ Sbjct: 82 VVNLYGEIGNGVEDQVKKLKDGMEAAYKNPQAKAIVIRANSPGGSPVVSNTAFEEIRRLK 141 Query: 154 KQYPKKPIYVVVEEVCASGGYYIAAAADKIFVNKASLVGSVGVLMDGFGFTGLMDKLGVE 213 Q+P P+Y+V E++CASG YYIAAAADKI+ + +S+VGS+GV+ F TGLM+K+GV+ Sbjct: 142 AQHPGIPVYLVAEDMCASGCYYIAAAADKIYADPSSIVGSIGVIGSSFDATGLMEKIGVK 201 Query: 214 RRLLTAGENKSFLDPFSPQSPKQREYAQSMLQEIHQQFIEVVRQGRGARLK--ETPDTFS 271 RR+ AG NK DPFSP++P+Q + + ML IH +FI+ V+ GRG RLK + PD FS Sbjct: 202 RRVKIAGSNKGMGDPFSPETPEQSKIWEEMLTGIHGEFIKAVKTGRGGRLKFRQYPDVFS 261 Query: 272 GLVWTGSKAVELGLADGFGTVDSVARDEIKAEDVVDYTQTENLSERVLKKFGVAFGA 328 G V+TG+ A+++GL DG G + SVARD +KA DVVDYT ++ + ++FG A Sbjct: 262 GRVYTGADALKVGLVDGLGNIYSVARDVVKAPDVVDYTPKDDFGRILGRRFGAELKA 318 >AGc1130 [OU] COG0616 Periplasmic serine proteases (ClpP class) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 289 Score = 178 bits (452), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 91/184 (49%), Positives = 124/184 (67%), Gaps = 1/184 (0%) Query: 114 PALDKAFAADDSVGVILKINSPGGSPVQAGMINDEITRLRKQYPKKPIYVVVEEVCASGG 173 P L+KAFA D+ V + +NSPGGSPVQA MI + I +L ++ KK + + VE+V ASGG Sbjct: 47 PLLEKAFAVKDAPAVAISLNSPGGSPVQARMIYNRIRQLAEEKDKK-VLIFVEDVAASGG 105 Query: 174 YYIAAAADKIFVNKASLVGSVGVLMDGFGFTGLMDKLGVERRLLTAGENKSFLDPFSPQS 233 Y IA A D+I + S+VGS+GV+ GFGF ++ K+GVERR+ TAGENK LDPF P+ Sbjct: 106 YMIALAGDEIIADPTSIVGSIGVVSGGFGFPEMLRKIGVERRVYTAGENKVILDPFQPEK 165 Query: 234 PKQREYAQSMLQEIHQQFIEVVRQGRGARLKETPDTFSGLVWTGSKAVELGLADGFGTVD 293 +Y +S+ EIH FI++V+ RG++LK FSGL WTG + ++LGL DG G + Sbjct: 166 EGDIDYLKSLQVEIHNVFIDMVKMRRGSKLKGDDALFSGLFWTGMRGLDLGLIDGLGDMR 225 Query: 294 SVAR 297 V R Sbjct: 226 EVLR 229 >SMc00857 [OU] COG0616 Periplasmic serine proteases (ClpP class) Sme Sinorhizobium meliloti Length = 288 Score = 175 bits (443), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 91/190 (47%), Positives = 123/190 (64%), Gaps = 5/190 (2%) Query: 112 VIPALDKAFAADDSVGVILKINSPGGSPVQAGMINDEITRLRKQYPKKPIYVVVEEVCAS 171 V P L+KAF+ ++ V + INSPGGSPVQ+ +I I L Q +K + + VE+V AS Sbjct: 45 VAPLLEKAFSVKEAPAVAISINSPGGSPVQSRLIYQRIRDL-AQEKRKRVLIFVEDVAAS 103 Query: 172 GGYYIAAAADKIFVNKASLVGSVGVLMDGFGFTGLMDKLGVERRLLTAGENKSFLDPFSP 231 GGY IA A D+I + S+VGS+GV+ GFGF L+ K+GVERR+ TAGENK LDPF P Sbjct: 104 GGYMIALAGDEIIADPTSIVGSIGVVSGGFGFPDLLKKIGVERRVYTAGENKVVLDPFQP 163 Query: 232 QSPKQREYAQSMLQEIHQQFIEVVRQGRGARLKETPDTFSGLVWTGSKAVELGLADGFGT 291 + + E+ + + EIH FI++V+ RG+ L + PD FSGL WTG + ELGL D G Sbjct: 164 EKERDIEFLKGLQLEIHDIFIQMVKSRRGSLLADHPDLFSGLFWTGQRGQELGLVDALGD 223 Query: 292 VDSVARDEIK 301 + R E+K Sbjct: 224 I----RGEVK 229 >mll7424 [OU] COG0616 Periplasmic serine proteases (ClpP class) Mlo Mesorhizobium loti Length = 286 Score = 174 bits (442), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 93/214 (43%), Positives = 139/214 (64%), Gaps = 6/214 (2%) Query: 94 LVEIKGAIDSEGQGSAGVVIPA----LDKAFAADDSVGVILKINSPGGSPVQAGMINDEI 149 ++ + G I + GQ + + + ++KAF+ D + V + INSPGGSPVQ+ +I I Sbjct: 22 VIRLHGTIMAGGQFRQNLSLASTAGLIEKAFSFD-APAVAISINSPGGSPVQSRLIFRRI 80 Query: 150 TRLRKQYPKKPIYVVVEEVCASGGYYIAAAADKIFVNKASLVGSVGVLMDGFGFTGLMDK 209 L + KK + V VE+V ASGGY IA A D+IF + +S+VGS+GV+ FGF LM K Sbjct: 81 RDLAAEKNKK-VLVFVEDVAASGGYMIAVAGDEIFADPSSIVGSIGVVSASFGFPELMKK 139 Query: 210 LGVERRLLTAGENKSFLDPFSPQSPKQREYAQSMLQEIHQQFIEVVRQGRGARLKETPDT 269 +GVERR+ TAG+NK+ LDPF P+ + E +++ E+H+ FI++V++ RG +LK+ PD Sbjct: 140 IGVERRVHTAGQNKAVLDPFKPEKKEDVERLKALQLEVHETFIDLVKERRGTKLKDDPDL 199 Query: 270 FSGLVWTGSKAVELGLADGFGTVDSVARDEIKAE 303 F+GL WTG K +ELGL D G + +V + A+ Sbjct: 200 FTGLFWTGKKGLELGLVDALGDMRTVLKTRFGAK 233 >BMEI1535_2 [OU] COG0616 Periplasmic serine proteases (ClpP class) Bme Brucella melitensis Length = 340 Score = 169 bits (429), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 97/227 (42%), Positives = 136/227 (59%), Gaps = 19/227 (8%) Query: 80 FNRIENEPLGPHTALVEIKGAIDSEGQG---------SAGVVIPALDKAFAADDSVGVIL 130 F +E E +V + GAI + G +AG+ L+KAFA + V + Sbjct: 63 FRAVETE-----IPVVRLHGAIMTGGTSLRPTLSLASTAGI----LEKAFADKHAPAVAI 113 Query: 131 KINSPGGSPVQAGMINDEITRLRKQYPKKPIYVVVEEVCASGGYYIAAAADKIFVNKASL 190 INSPGG+PVQ+ +I I L ++ KK ++V VE+V ASGGY IA A D+I + +S+ Sbjct: 114 SINSPGGAPVQSRLIYRRIRDLAAEHQKK-VFVFVEDVAASGGYMIALAGDEIIADPSSI 172 Query: 191 VGSVGVLMDGFGFTGLMDKLGVERRLLTAGENKSFLDPFSPQSPKQREYAQSMLQEIHQQ 250 VGS+GV+ FGF L+ K+GVERR+ TAG NK LDPF P+ + E +++ EIH Sbjct: 173 VGSIGVVSASFGFPELLKKIGVERRVYTAGSNKVTLDPFQPEKAEDIERLKALQLEIHAT 232 Query: 251 FIEVVRQGRGARLKETPDTFSGLVWTGSKAVELGLADGFGTVDSVAR 297 FI++V++ R +L + PD FSGL WTG+ A LGL DG G + S R Sbjct: 233 FIDMVKERRAGKLGDNPDLFSGLFWTGTTAASLGLIDGLGDMLSFLR 279 >RC0545 [OU] COG0616 Periplasmic serine proteases (ClpP class) Rco Rickettsia conorii Length = 304 Score = 146 bits (369), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 77/212 (36%), Positives = 128/212 (60%), Gaps = 6/212 (2%) Query: 93 ALVEIKGAIDSEGQGSAGVVIPALD----KAFAADDSVGVILKINSPGGSPVQAGMINDE 148 A++ + G I +G+ + +L+ KAF + L INSPGGSPVQ+ +I Sbjct: 42 AVLRLSGVIGKVSTMQSGLTLESLNALIEKAFKIKKLKALCLIINSPGGSPVQSELIAKR 101 Query: 149 ITRLRKQYPKKPIYVVVEEVCASGGYYIAAAADKIFVNKASLVGSVGVLMDGFGFTGLMD 208 I L ++ K IY +E++ ASGGY++A + D+I+ +S++GS+GV+ GFGF ++ Sbjct: 102 IRDLAEE-NKIKIYSFIEDMAASGGYWLACSGDRIYALPSSVIGSIGVVSSGFGFHEAIN 160 Query: 209 KLGVERRLLTAGENKSFLDPFSPQSPKQREYAQSMLQEIHQQFIEVVRQGRGARLKETPD 268 KLG+ERR+ T G+NKS LDPF P + + + + +++++ FIE V+ R +L + + Sbjct: 161 KLGIERRVYTEGKNKSVLDPFKPINKDDLKIIKDLQKQVYEHFIEYVKTRRAGKLTQQDE 220 Query: 269 T-FSGLVWTGSKAVELGLADGFGTVDSVARDE 299 F+G W G A++ GL DG G + SV +++ Sbjct: 221 ILFNGEFWAGQTALDYGLIDGIGDIYSVMKEK 252 >RP398 [OU] COG0616 Periplasmic serine proteases (ClpP class) Rpr Rickettsia prowazekii Length = 308 Score = 143 bits (361), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 74/213 (34%), Positives = 127/213 (59%), Gaps = 6/213 (2%) Query: 92 TALVEIKGAIDSEGQGSAGVVIPALD----KAFAADDSVGVILKINSPGGSPVQAGMIND 147 A++ + G I +G+ + +L+ K F + L INSPGGSPVQ+ +I Sbjct: 45 VAVLRLSGVIGKVSTMQSGLTLESLNELIEKTFKIKKLKALCLIINSPGGSPVQSELIAK 104 Query: 148 EITRLRKQYPKKPIYVVVEEVCASGGYYIAAAADKIFVNKASLVGSVGVLMDGFGFTGLM 207 I L K+ K +Y +E++ ASGGY++A + D+I+ +S++GS+GV+ GFGF + Sbjct: 105 RIRDLAKE-NKIKVYSFIEDMAASGGYWLACSGDQIYALPSSVIGSIGVVSSGFGFHEAI 163 Query: 208 DKLGVERRLLTAGENKSFLDPFSPQSPKQREYAQSMLQEIHQQFIEVVRQGRGARLKETP 267 +KLG+ERR+ T G+NK+ LDPF P + + + + +++++ F+E V+ R +L + Sbjct: 164 NKLGIERRVYTEGKNKAVLDPFKPINKDDLKIIKDLQKQVYEHFVEYVKNRRAGKLTQQD 223 Query: 268 DT-FSGLVWTGSKAVELGLADGFGTVDSVARDE 299 + F+G W G A++ GL DG G + SV +++ Sbjct: 224 EILFNGEFWAGQTALDYGLIDGIGDMYSVIKEK 256