BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0059.p (361 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value aq_183 [S] COG3034 Uncharacterized protein conserved in bacteria... 102 1e-21 jhp0467 [S] COG3034 Uncharacterized protein conserved in bacteri... 90 6e-18 HP0518 [S] COG3034 Uncharacterized protein conserved in bacteria... 88 3e-17 Cj0906c [S] COG3034 Uncharacterized protein conserved in bacteri... 81 4e-15 >aq_183 [S] COG3034 Uncharacterized protein conserved in bacteria Aae Aquifex aeolicus Length = 397 Score = 102 bits (255), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 74/291 (25%), Positives = 138/291 (47%), Gaps = 17/291 (5%) Query: 72 RIRSLQEKPDPNLIPKAVLQVGEDQKNVLVVDTTRSRMYVYENQGGELKFQTDFYISQGR 131 +IR + EK P VL + V +V+ ++V++ + K + + ++ G Sbjct: 114 KIRKILEKRFKEAPP--VLVENPENHYVFLVEKMSQYLFVFKGK----KLEGMYPVTTGM 167 Query: 132 FGANKSKSGDQRTPIGVYYVNNRIPGPKLPDFYGTGALPLSYPNEWDKRNGRSGYGIWLH 191 +K + GD +TP GVYY IP +L + YG A+ L+YPN +DK G++G GIWLH Sbjct: 168 NIGDKEREGDGKTPEGVYYFTRFIPPEQLSEIYGGIAVALNYPNPYDKLLGKTGSGIWLH 227 Query: 192 GTPSDNFSRPPLSSDGCVVLANPDLQS-LYSTAEVGKTVVVISQHVQFVDKNEWARQRDA 250 G+ + + P S+ GCVV L++ + + T++ I + + + + + Sbjct: 228 GSNEKDRDKLPFSTRGCVVAQTDVLKTEIVPKINLSNTLIGIYKVIP------QSLEVEN 281 Query: 251 ASAILEQWVQSLENADPEKVLSYYSPEFRSAQGESLATWFGRQQKSLNGARYTSVKLRDV 310 + W + E D + +S+YS FR +G L W +++++ ++ V + ++ Sbjct: 282 VKEFILSWKNAWEKKDLNRFISFYSKHFR-WKGGGLKEWKDYKKRTILSKKFIKVDISNL 340 Query: 311 SLFRYPGTPED---MIVSTFTQESAVGKSKNAIRKRQYWVREGSQWKIIYE 358 S+ + +D V F Q+ + KR Y V+E + K++ E Sbjct: 341 SILAFSKLGDDEPRYYVIEFYQKYRSDTYSDEGIKRMYVVKEDGKLKVLSE 391 >jhp0467 [S] COG3034 Uncharacterized protein conserved in bacteria jHp Helicobacter pylori J99 Length = 330 Score = 90.1 bits (222), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 69/275 (25%), Positives = 123/275 (44%), Gaps = 20/275 (7%) Query: 94 EDQKNVLVVDTTRSRMYVYENQGGELKFQTDFYISQGRFGANKSKSGDQRTPIGVYYVNN 153 ++++ + V D ++ + YE + LK G +K+ GD TPIGVY + Sbjct: 65 QNKQFLFVADKSKPSLEFYEIENNMLKKINSSKALVGSKKGDKTLEGDLATPIGVYRITQ 124 Query: 154 RIPGPKLPDFYGTGALPLSYPNEWDKRNGRSGYGIWLHGTPSDNFSRPPLSSDGCVVLAN 213 ++ +L +YG A +YPN +D R+G+GIW+HG P N R L++ GC+ + N Sbjct: 125 KLE--RLDQYYGVLAFVTNYPNLYDTLKKRTGHGIWVHGMPL-NGDRNELNTKGCIAIEN 181 Query: 214 PDLQSLYSTAEVGKTVVVISQHVQFVDKNEWARQRDAASAILE---QWVQSLENADPEKV 270 P L S Y G+ +I+ +F ++ S IL QW ++ D E+ Sbjct: 182 PILSS-YDKVLKGEKAFLITYEDKFS-----PSTKEELSMILSSLFQWKEAWARGDFERY 235 Query: 271 LSYYSPEFRSAQGESLATWFGRQQKSLNGARYTSVKLRDVSLFRYPGTPEDMIVSTF--- 327 + +Y+P F G S + +++ ++ +++ YP + + Sbjct: 236 MRFYNPNFTRYDGMSFNAFKEYKKRVFAKNEKKNIAFSSINVIPYPNSQNKRLFYVVFDQ 295 Query: 328 ----TQESAVGKSKNAIRKRQYWVREGSQWKIIYE 358 Q++ + S N+ +K Y E +Q II E Sbjct: 296 DYKAYQQNKLSYSSNS-QKELYVEIENNQASIIME 329 >HP0518 [S] COG3034 Uncharacterized protein conserved in bacteria Hpy Helicobacter pylori 26695 Length = 330 Score = 87.8 bits (216), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 68/275 (24%), Positives = 124/275 (45%), Gaps = 20/275 (7%) Query: 94 EDQKNVLVVDTTRSRMYVYENQGGELKFQTDFYISQGRFGANKSKSGDQRTPIGVYYVNN 153 ++++ + V + ++ + YE + LK G +K+ GD TPIGVY + Sbjct: 65 QNKQFLFVANKSKPSLEFYEIENNMLKKINSSKALVGSKKGDKTLEGDLATPIGVYRITQ 124 Query: 154 RIPGPKLPDFYGTGALPLSYPNEWDKRNGRSGYGIWLHGTPSDNFSRPPLSSDGCVVLAN 213 ++ +L +YG A +YPN +D R+G+GIW+HG P N R L++ GC+ + N Sbjct: 125 KLE--RLDQYYGVLAFVTNYPNLYDTLKKRTGHGIWVHGMPL-NGDRNELNTKGCIAIEN 181 Query: 214 PDLQSLYSTAEVGKTVVVISQHVQFVDKNEWARQRDAASAILE---QWVQSLENADPEKV 270 P L S Y G+ +I+ +F + ++ S IL QW ++ D E+ Sbjct: 182 PLLSS-YDKVLKGEKAFLITYEDKF-----FPSTKEELSMILSSLFQWKEAWARGDFERY 235 Query: 271 LSYYSPEFRSAQGESLATWFGRQQKSLNGARYTSVKLRDVSLFRYPGTPED-MIVSTFTQ 329 + +Y+P F G + +++ ++ +++ YP + + F Q Sbjct: 236 MRFYNPNFTRYDGMKFNAFKEYKKRVFAKNEKKNIAFSSINVIPYPNSQNKRLFYVVFDQ 295 Query: 330 E------SAVGKSKNAIRKRQYWVREGSQWKIIYE 358 + + + S N+ +K Y E +Q II E Sbjct: 296 DYKAYQHNKLSYSSNS-QKELYIEIENNQVSIIME 329 >Cj0906c [S] COG3034 Uncharacterized protein conserved in bacteria Cje Campylobacter jejuni Length = 325 Score = 80.9 bits (198), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 64/235 (27%), Positives = 104/235 (44%), Gaps = 18/235 (7%) Query: 90 LQVGEDQKNVLVVDTTRS----RMYVYENQGGELKFQTDFY---ISQGRFGANKSKSGDQ 142 + +G NV +V T ++ R+Y YE+ K + DF I G G +K GD Sbjct: 56 ISLGYYDDNVAIVLTNKTDKILRVYSYEDG----KIRKDFEQKEIITGLMG-DKKIEGDL 110 Query: 143 RTPIGVYYVNNRIPGPKLPDFYGTGALPLSYPNEWDKRNGRSGYGIWLHGTPSDNFSRPP 202 +TP+G Y + + P P +YG A +YPN DK G++G GIW+HG P D Sbjct: 111 KTPVGFYELGRKF-NPGDP-YYGPFAFATTYPNLLDKVQGKTGGGIWIHGYPLDGSRLDE 168 Query: 203 LSSDGCVVLANPDLQSLYSTAEVGKTVVVISQHVQFVDKNEWARQRDAASAILEQWVQSL 262 + GC+ L N +L+ + K V+ + + K + Q + A L W + Sbjct: 169 FKTRGCIALFNNNLEKFAKVVQDKKVFVMTEEKEKIRAKKD---QIASLLADLFTWKLAW 225 Query: 263 ENADPEKVLSYYSP-EFRSAQGESLATWFGRQQKSLNGARYTSVKLRDVSLFRYP 316 N+D LS+Y EF+ + ++ + +K D+++ YP Sbjct: 226 TNSDTNAYLSFYDEQEFKRFDKMKFEQFASMKKSIFSRKEDKKIKFSDINISPYP 280