BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0056.p (263 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ybbF [S] COG2908 Uncharacterized protein conserved in bacteria E... 205 7e-53 ZybbF [S] COG2908 Uncharacterized protein conserved in bacteria ... 203 3e-52 ECs0586 [S] COG2908 Uncharacterized protein conserved in bacteri... 203 3e-52 YPO3075 [S] COG2908 Uncharacterized protein conserved in bacteri... 195 8e-50 RSc1163 [S] COG2908 Uncharacterized protein conserved in bacteri... 194 1e-49 VC1850 [S] COG2908 Uncharacterized protein conserved in bacteria... 184 3e-46 HI0735 [S] COG2908 Uncharacterized protein conserved in bacteria... 183 3e-46 STM0535 [S] COG2908 Uncharacterized protein conserved in bacteri... 182 7e-46 PA1792 [S] COG2908 Uncharacterized protein conserved in bacteria... 181 2e-45 NMB0544 [S] COG2908 Uncharacterized protein conserved in bacteri... 170 2e-42 >ybbF [S] COG2908 Uncharacterized protein conserved in bacteria Eco Escherichia coli K12 Length = 240 Score = 205 bits (522), Expect = 7e-53, Method: Compositional matrix adjust. Identities = 108/234 (46%), Positives = 142/234 (60%), Gaps = 6/234 (2%) Query: 16 LFVSDLHLQASLPRTTAAFLAFLQSHAVQTQQLYLLGDIFEYWAGDDDLATPYNQFIADA 75 LF++DLHL P TA FL FL A + LY+LGD+FE W GDDD P ++ +A A Sbjct: 4 LFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDD-PNPLHRKMAAA 62 Query: 76 LKALQAQGVQLYWMAGNRDFLVGQAFADAAGLTLLQDPHVITAAGRRLTLAHGDAQCTDD 135 +KA+ GV Y++ GNRDFL+G+ FA +G+TLL + V+ GRR+ + HGD CTDD Sbjct: 63 IKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDD 122 Query: 136 HAYMAFRAQVRQPAYQQQFLAMPLAQRKAIIEGIRKNSQDANQSKEMAIMDVNAGAIDTL 195 Y AFRA+V +P Q FLA+PL RK I +R NS++AN SK +AIMDVN A+ + Sbjct: 123 AGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSA 182 Query: 196 FAQTGTDTLIHGHTHRPALHRLGEGPAGKLRYVLPDWEYDVETPRGGWISLTAD 249 + LIHGHTHRPA+H L R VL W + G + +TAD Sbjct: 183 MEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTE-----GSMVKVTAD 231 >ZybbF [S] COG2908 Uncharacterized protein conserved in bacteria EcZ Escherichia coli O157:H7 EDL933 Length = 240 Score = 203 bits (517), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 107/234 (45%), Positives = 141/234 (60%), Gaps = 6/234 (2%) Query: 16 LFVSDLHLQASLPRTTAAFLAFLQSHAVQTQQLYLLGDIFEYWAGDDDLATPYNQFIADA 75 LF++DLHL P TA FL FL A + LY+LGD+FE W GDDD P ++ +A A Sbjct: 4 LFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDD-PNPLHRQMAAA 62 Query: 76 LKALQAQGVQLYWMAGNRDFLVGQAFADAAGLTLLQDPHVITAAGRRLTLAHGDAQCTDD 135 +KA+ GV Y++ GNRDFL+G+ FA +G+TLL + V+ GRR+ + HGD CTDD Sbjct: 63 IKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDD 122 Query: 136 HAYMAFRAQVRQPAYQQQFLAMPLAQRKAIIEGIRKNSQDANQSKEMAIMDVNAGAIDTL 195 Y AFR +V +P Q FLA+PL RK I +R NS++AN SK +AIMDVN A+ + Sbjct: 123 AGYQAFRTKVHKPWLQTLFLALPLFVRKRIAVRMRANSKEANSSKSLAIMDVNQNAVVSA 182 Query: 196 FAQTGTDTLIHGHTHRPALHRLGEGPAGKLRYVLPDWEYDVETPRGGWISLTAD 249 + LIHGHTHRPA+H L R VL W + G + +TAD Sbjct: 183 MEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTE-----GSMVKVTAD 231 >ECs0586 [S] COG2908 Uncharacterized protein conserved in bacteria Ecs Escherichia coli O157:H7 Length = 240 Score = 203 bits (517), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 107/234 (45%), Positives = 141/234 (60%), Gaps = 6/234 (2%) Query: 16 LFVSDLHLQASLPRTTAAFLAFLQSHAVQTQQLYLLGDIFEYWAGDDDLATPYNQFIADA 75 LF++DLHL P TA FL FL A + LY+LGD+FE W GDDD P ++ +A A Sbjct: 4 LFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDD-PNPLHRQMAAA 62 Query: 76 LKALQAQGVQLYWMAGNRDFLVGQAFADAAGLTLLQDPHVITAAGRRLTLAHGDAQCTDD 135 +KA+ GV Y++ GNRDFL+G+ FA +G+TLL + V+ GRR+ + HGD CTDD Sbjct: 63 IKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDD 122 Query: 136 HAYMAFRAQVRQPAYQQQFLAMPLAQRKAIIEGIRKNSQDANQSKEMAIMDVNAGAIDTL 195 Y AFR +V +P Q FLA+PL RK I +R NS++AN SK +AIMDVN A+ + Sbjct: 123 AGYQAFRTKVHKPWLQTLFLALPLFVRKRIAVRMRANSKEANSSKSLAIMDVNQNAVVSA 182 Query: 196 FAQTGTDTLIHGHTHRPALHRLGEGPAGKLRYVLPDWEYDVETPRGGWISLTAD 249 + LIHGHTHRPA+H L R VL W + G + +TAD Sbjct: 183 MEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTE-----GSMVKVTAD 231 >YPO3075 [S] COG2908 Uncharacterized protein conserved in bacteria Ype Yersinia pestis Length = 240 Score = 195 bits (496), Expect = 8e-50, Method: Compositional matrix adjust. Identities = 102/237 (43%), Positives = 136/237 (57%), Gaps = 6/237 (2%) Query: 15 ALFVSDLHLQASLPRTTAAFLAFLQSHAVQTQQLYLLGDIFEYWAGDDDLATPYNQFIAD 74 LF++DLHL P TA FL F+Q A+ LY+LGD+FE W GDDD Y Q +A Sbjct: 3 TLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQ-VAA 61 Query: 75 ALKALQAQGVQLYWMAGNRDFLVGQAFADAAGLTLLQDPHVITAAGRRLTLAHGDAQCTD 134 ALK+LQ QGV Y++ GNRDFL+G+ FA+ +G+ LL + +V+ GR++ + HGD CTD Sbjct: 62 ALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTD 121 Query: 135 DHAYMAFRAQVRQPAYQQQFLAMPLAQRKAIIEGIRKNSQDANQSKEMAIMDVNAGAIDT 194 D Y FR +V P Q+ FL +PL R I +R SQ N K IMDVN+ A+ Sbjct: 122 DTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSERIMDVNSKAVID 181 Query: 195 LFAQTGTDTLIHGHTHRPALHRLGEGPAGKLRYVLPDWEYDVETPRGGWISLTADGA 251 F + +IHGHTHRPA+H + R VL W + G + +TAD Sbjct: 182 AFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVE-----GSMVKVTADNV 233 >RSc1163 [S] COG2908 Uncharacterized protein conserved in bacteria Rso Ralstonia solanacearum Length = 268 Score = 194 bits (494), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 111/246 (45%), Positives = 147/246 (59%), Gaps = 14/246 (5%) Query: 16 LFVSDLHLQASLPRTTAAFLAFLQSHAVQTQQLYLLGDIFEYWAGDDDLATPYNQFIADA 75 F+SDLHL A +P T AAF F+++ A + + L +LGD FEYW GD++LA P+++ +A Sbjct: 21 FFISDLHLSAGMPATAAAFERFVRTRAREARTLVILGDFFEYWVGDEELADPFHRHVAAL 80 Query: 76 LKALQAQGVQLYWMAGNRDFLVGQAFADAAGLTLLQDPHVITAAGRRLTLAHGDAQCTDD 135 L L G ++ M GNRDFL+G+ F TLL DP V+ A G R+ LAHGDA CT D Sbjct: 81 LAELAQAGTRVLLMHGNRDFLLGKRFLATTQATLLPDPSVLEADGLRIVLAHGDALCTRD 140 Query: 136 HAYMAFRAQVRQPAYQQQFLAMPLAQRKAIIEGIRKNSQD--------ANQSKEMAIM-D 186 AYM FR R+ Q+ FLAMPL R I + +R +S+ A + + A+M D Sbjct: 141 AAYMRFRRWTRKRWVQRLFLAMPLRWRLRIAQKMRADSEAGRALSANVAGEPRAAAMMGD 200 Query: 187 VNAGAIDTLFAQTGTDTLIHGHTHRPALHRLGEGPAGKLRYVLPDWEYDVETPRGGWISL 246 V A+D LF G LIHGHTHRP LH P G+ R+VL DW++D PRG ++ L Sbjct: 201 VAPEAVDALFKAAGIPLLIHGHTHRPRLH---HEPGGE-RWVLSDWDFDHAQPRGSFLRL 256 Query: 247 TADGAL 252 DG L Sbjct: 257 Q-DGVL 261 >VC1850 [S] COG2908 Uncharacterized protein conserved in bacteria Vch Vibrio cholerae Length = 242 Score = 184 bits (466), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 91/219 (41%), Positives = 129/219 (58%), Gaps = 2/219 (0%) Query: 15 ALFVSDLHLQASLPRTTAAFLAFLQSHAVQTQQLYLLGDIFEYWAGDDDLATPYNQFIAD 74 LF+SDLHL P TA+F+ F++ A++ LY+LGD+F++W GDDD T + + I Sbjct: 3 TLFISDLHLSPKHPDITASFIQFMREEAIKADALYVLGDLFDFWIGDDD-PTTFAEQIKS 61 Query: 75 ALKALQAQGVQLYWMAGNRDFLVGQAFADAAGLTLLQDPHVITAAGRRLTLAHGDAQCTD 134 + L QGV Y+ GNRDFLVG+ FA G+ LL D VI G++ + HGD CT Sbjct: 62 EFRQLTQQGVPCYFTKGNRDFLVGKRFAQQTGVQLLPDEAVIDLYGQKAVVLHGDTLCTQ 121 Query: 135 DHAYMAFRAQVRQPAYQQQFLAMPLAQRKAIIEGIRKNSQDANQSKEMAIMDVNAGAIDT 194 D Y+ FRA+V QP Q+ F +P A ++ ++ I+ + +D Q K M IMDV + Sbjct: 122 DTRYLEFRAKVHQPWLQRLFGLLPFALKQKLVRKIQSDIRDDKQHKSMMIMDVTPSEVIA 181 Query: 195 LFAQTGTDTLIHGHTHRPALHRL-GEGPAGKLRYVLPDW 232 + + D +IHGHTHRPA+H + + K R VL DW Sbjct: 182 VMHRYNVDLMIHGHTHRPAIHSIQTDDQTLKTRIVLGDW 220 >HI0735 [S] COG2908 Uncharacterized protein conserved in bacteria Hin Haemophilus influenzae Length = 237 Score = 183 bits (464), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 94/218 (43%), Positives = 127/218 (58%), Gaps = 5/218 (2%) Query: 15 ALFVSDLHLQASLPRTTAAFLAFLQSHAVQTQQLYLLGDIFEYWAGDDDLATPYNQFIAD 74 + F+SDLHL + P TA F+ F+Q+ A Q ++LY+LGD+F++W GDD+ + Q + D Sbjct: 4 SYFISDLHLSETQPELTALFVDFMQNLAPQAERLYILGDLFDFWIGDDEQSALIQQ-VKD 62 Query: 75 ALKALQAQGVQLYWMAGNRDFLVGQAFADAAGLTLLQDPHVITAAGRRLTLAHGDAQCTD 134 +K + QGVQ Y+ GNRDFL+G+ F+ G LL D +IT +++ L HGD C D Sbjct: 63 LIKFVSDQGVQCYFQHGNRDFLIGERFSKETGAQLLPDYQLITLYDKKILLCHGDTLCID 122 Query: 135 DHAYMAFRAQVRQPAYQQQFLAMPLAQRKAIIEGIRKNSQDANQSKEMAIMDVNAGAIDT 194 D AY FR +V Q Q+ FL +PL R I E IR S Q+K IMDVN Sbjct: 123 DEAYQQFRRRVHQKWLQRLFLCLPLKVRVIIAEKIRAKSNQDKQAKSQEIMDVNQAFTAE 182 Query: 195 LFAQTGTDTLIHGHTHRPALHRLGEGPAGKLRYVLPDW 232 + G + LIHGHTHR A+H+ E R VL DW Sbjct: 183 KVQEFGVNLLIHGHTHREAIHQQEEFT----RIVLGDW 216 >STM0535 [S] COG2908 Uncharacterized protein conserved in bacteria Sty Salmonella typhimurium LT2 Length = 240 Score = 182 bits (462), Expect = 7e-46, Method: Compositional matrix adjust. Identities = 101/236 (42%), Positives = 134/236 (56%), Gaps = 6/236 (2%) Query: 16 LFVSDLHLQASLPRTTAAFLAFLQSHAVQTQQLYLLGDIFEYWAGDDDLATPYNQFIADA 75 LF++DLHLQ P A FL FL A Q LY+LGD+FE W GDDD P ++ +A A Sbjct: 4 LFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFEAWIGDDD-PNPLHREMAVA 62 Query: 76 LKALQAQGVQLYWMAGNRDFLVGQAFADAAGLTLLQDPHVITAAGRRLTLAHGDAQCTDD 135 +K+L GV +++ GNRDFL+G+ FA +G+ LL V+ GR + + HGD CTDD Sbjct: 63 IKSLVDSGVPCFFIHGNRDFLIGKRFARESGMILLPQEKVLDLYGRNVLIMHGDTLCTDD 122 Query: 136 HAYMAFRAQVRQPAYQQQFLAMPLAQRKAIIEGIRKNSQDANQSKEMAIMDVNAGAIDTL 195 Y AFRA+V P Q+ FL +PL R+ I +R S+ AN SK + IMDVNA + Sbjct: 123 AGYQAFRAKVHNPWVQRLFLTLPLFIRRRIAARMRAGSKAANSSKSLDIMDVNAQTVVAE 182 Query: 196 FAQTGTDTLIHGHTHRPALHRLGEGPAGKLRYVLPDWEYDVETPRGGWISLTADGA 251 + LIHGHTHRPA+H L R VL W ++ G + +T D Sbjct: 183 MEKHRVQWLIHGHTHRPAVHELSANDQPAFRVVLGAWHHE-----GSMVKVTPDNV 233 >PA1792 [S] COG2908 Uncharacterized protein conserved in bacteria Pae Pseudomonas aeruginosa Length = 240 Score = 181 bits (458), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 102/240 (42%), Positives = 132/240 (55%), Gaps = 8/240 (3%) Query: 15 ALFVSDLHLQASLPRTTAAFLAFLQSHAVQTQQLYLLGDIFEYWAGDDDLATPYNQFIAD 74 LF+SDLHL+A P T AFL+FL A + + LY+LGD FE W GDD + + + IA Sbjct: 3 VLFISDLHLEAERPDITRAFLSFLDERARRAEALYILGDFFEAWIGDDGMDA-FQRSIAQ 61 Query: 75 ALKALQAQGVQLYWMAGNRDFLVGQAFADAAGLTLLQDPHVITAAGRRLTLAHGDAQCTD 134 +L+ + G ++Y M GNRDFL+G+AF AG TLL DP VI G + L HGD+ CT Sbjct: 62 SLRQVADGGTRIYLMHGNRDFLIGKAFCREAGCTLLPDPSVIDLYGEPVLLMHGDSLCTR 121 Query: 135 DHAYMAFRAQVRQPAYQQQFLAMPLAQRKAIIEGIRKNSQDANQSKEMAIMDVNAGAIDT 194 D AYM R +R P +PLA R + +RK S+ + K + I+DV + Sbjct: 122 DEAYMRLRRWLRNPLTLWVLRHLPLATRHKLARKLRKESRAQTRMKAVDIIDVTPEEVPR 181 Query: 195 LFAQTGTDTLIHGHTHRPALHRLGEGPAGKLRYVLPDWEYDVETPRGGWISLTADGALHR 254 + G TLIHGHTHRPA H L R VL DW+ R GW +L D HR Sbjct: 182 VMRGHGVRTLIHGHTHRPAEHPLDIDGQPARRIVLGDWD------RQGW-ALEIDANGHR 234 >NMB0544 [S] COG2908 Uncharacterized protein conserved in bacteria Nme Neisseria meningitidis MC58 Length = 240 Score = 170 bits (431), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 93/222 (41%), Positives = 125/222 (56%), Gaps = 6/222 (2%) Query: 15 ALFVSDLHLQASLPRTTAAFLAFLQSHAV-QTQQLYLLGDIFEYWAGDDDLATPYNQFIA 73 A F+SDLHL P TA L FL+S A Q + +Y+LGD+F++W GDD++ + N +A Sbjct: 4 AYFISDLHLSEKQPELTALLLRFLRSSAAGQARAIYILGDLFDFWVGDDEV-SELNTSVA 62 Query: 74 DALKALQAQGVQLYWMAGNRDFLVGQAFADAAGLTLLQDPHVITAAGRRLTLAHGDAQCT 133 ++ L +GV ++++ GNRDFL+GQ F AG+TLL D V+ G + + HGD CT Sbjct: 63 REIRKLSDKGVAVFFVRGNRDFLIGQDFCRQAGMTLLPDYSVLDLFGCKTLICHGDTLCT 122 Query: 134 DDHAYMAFRAQVRQPAYQQQFLAMPLAQRKAIIEGIRKNSQDANQSKEMAIMDVNAGAID 193 DD AY FR V + Q+ FL +PL R + IR+ S+ Q K IMDVNA Sbjct: 123 DDRAYQRFRKIVHRKRLQKLFLMLPLKWRTRLATKIRRVSKMEKQVKPADIMDVNAAFTA 182 Query: 194 TLFAQTGTDTLIHGHTHRPALHRLGEGPAGKLRYVLPDWEYD 235 G + LIHGHTHR +H G R VL DW D Sbjct: 183 RQVRAFGAERLIHGHTHREHIHH----ENGFTRIVLGDWHND 220