BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0054.p (258 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1229 [J] COG0566 rRNA methylases Rso Ralstonia solanacearum 377 e-105 NMA1127 [J] COG0566 rRNA methylases NmA Neisseria meningitidis Z... 275 7e-74 NMB0931 [J] COG0566 rRNA methylases Nme Neisseria meningitidis MC58 275 1e-73 yjfH [J] COG0566 rRNA methylases Eco Escherichia coli K12 251 1e-66 ZyjfH [J] COG0566 rRNA methylases EcZ Escherichia coli O157:H7 E... 251 1e-66 ECs5156 [J] COG0566 rRNA methylases Ecs Escherichia coli O157:H7 251 1e-66 STM4369 [J] COG0566 rRNA methylases Sty Salmonella typhimurium LT2 248 1e-65 YPO0381 [J] COG0566 rRNA methylases Ype Yersinia pestis 243 3e-64 PA4936 [J] COG0566 rRNA methylases Pae Pseudomonas aeruginosa 241 1e-63 HI0860 [J] COG0566 rRNA methylases Hin Haemophilus influenzae 240 2e-63 >RSc1229 [J] COG0566 rRNA methylases Rso Ralstonia solanacearum Length = 249 Score = 377 bits (969), Expect = e-105, Method: Compositional matrix adjust. Identities = 179/241 (74%), Positives = 210/241 (87%) Query: 15 KSKMIFGFHAVTSRIRHEASSVDEIYVDAERRDRRMLDLLHAAKEANVRIIQADDQRLAA 74 KSK++ GFHAVT+R+RH+A S+DEIY +A RRDRRM D L AA+ A VR+I AD++RL Sbjct: 3 KSKLLIGFHAVTARLRHDARSIDEIYFEANRRDRRMQDFLKAAEAAGVRMIPADNERLRG 62 Query: 75 MVGTRRHQGVVAKAAALSLARTLDELLDAVVGPPLLLILDGITDPHNLGACLRVADGAGA 134 + GT RHQGVVAKA ALSLA LDELLD + GPPLLL+LDG+TDPHNLGACLRVAD AGA Sbjct: 63 IAGTDRHQGVVAKAEALSLALNLDELLDGIEGPPLLLVLDGVTDPHNLGACLRVADAAGA 122 Query: 135 HAVIAPKDRAVGLNATAMKVSSGASDTVPYITVTNLARTMRDLKERGVWIIGTSDDAEKG 194 HAVIAPKDR+VG+N T KV+SGA++TVPYITVTNLART+R+L++RGVW+IGT+D+AE+ Sbjct: 123 HAVIAPKDRSVGINTTVAKVASGAAETVPYITVTNLARTLRELQQRGVWVIGTADEAEQD 182 Query: 195 LYEGDFTGPTALVMGSEGEGMRRLTRETCDVLVNIPMFGSVESLNVSVASGVCLYEARRQ 254 LY DF GP ALVMG+EGEGMRRLTRETCD LV+IPM GSVESLNVSVASGVCL+EA RQ Sbjct: 183 LYRADFKGPIALVMGAEGEGMRRLTRETCDTLVSIPMAGSVESLNVSVASGVCLFEAVRQ 242 Query: 255 R 255 R Sbjct: 243 R 243 >NMA1127 [J] COG0566 rRNA methylases NmA Neisseria meningitidis Z2491 Length = 261 Score = 275 bits (703), Expect = 7e-74, Method: Compositional matrix adjust. Identities = 136/240 (56%), Positives = 171/240 (71%) Query: 19 IFGFHAVTSRIRHEASSVDEIYVDAERRDRRMLDLLHAAKEANVRIIQADDQRLAAMVGT 78 I+GFHAV +R+ S+ E+Y+ + D R ++L A N+R+ AD RL A+ Sbjct: 18 IYGFHAVNARLWQNPKSIVELYIQEGKSDARTREVLEKAANENIRVYFADADRLNAISKG 77 Query: 79 RRHQGVVAKAAALSLARTLDELLDAVVGPPLLLILDGITDPHNLGACLRVADGAGAHAVI 138 RHQGVV A L+++L+ + PPLLLILDGITDPHNLGACLR AD G HAVI Sbjct: 78 ARHQGVVGFIDASKNHVHLEDVLENLSEPPLLLILDGITDPHNLGACLRTADAMGVHAVI 137 Query: 139 APKDRAVGLNATAMKVSSGASDTVPYITVTNLARTMRDLKERGVWIIGTSDDAEKGLYEG 198 APKD++ GLNAT KV+SGA++TVPYITVTNLART+R+LKE G+WIIGT LY Sbjct: 138 APKDKSAGLNATVSKVASGAAETVPYITVTNLARTLRELKEYGIWIIGTDMGGNADLYHC 197 Query: 199 DFTGPTALVMGSEGEGMRRLTRETCDVLVNIPMFGSVESLNVSVASGVCLYEARRQRLPK 258 D A VMG+EG+GMRRLTRE CD+LV+IPMFG+VES+NVSV++G+ L E RRQR+ K Sbjct: 198 DLPDSAAWVMGNEGDGMRRLTREHCDMLVSIPMFGTVESMNVSVSAGMVLSETRRQRVLK 257 >NMB0931 [J] COG0566 rRNA methylases Nme Neisseria meningitidis MC58 Length = 250 Score = 275 bits (702), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 135/240 (56%), Positives = 171/240 (71%) Query: 19 IFGFHAVTSRIRHEASSVDEIYVDAERRDRRMLDLLHAAKEANVRIIQADDQRLAAMVGT 78 I+GFHAV +R+ S+ E+Y+ + D R ++L A N+R+ AD RL A+ Sbjct: 7 IYGFHAVNARLWQNPKSIVELYIQEGKSDARTREVLEKAANENIRVYFADADRLNAISKG 66 Query: 79 RRHQGVVAKAAALSLARTLDELLDAVVGPPLLLILDGITDPHNLGACLRVADGAGAHAVI 138 RHQGVV A L+++L+ + PPLLLILDGITDPHNLGACLR AD G HAVI Sbjct: 67 ARHQGVVGFIDASKNHVHLEDVLENLSEPPLLLILDGITDPHNLGACLRTADAMGVHAVI 126 Query: 139 APKDRAVGLNATAMKVSSGASDTVPYITVTNLARTMRDLKERGVWIIGTSDDAEKGLYEG 198 APKD++ GLNAT KV+ GA++TVPYITVTNLART+R+LKE G+WIIGT E LY Sbjct: 127 APKDKSAGLNATVSKVACGAAETVPYITVTNLARTLRELKEYGIWIIGTDMSGESDLYHC 186 Query: 199 DFTGPTALVMGSEGEGMRRLTRETCDVLVNIPMFGSVESLNVSVASGVCLYEARRQRLPK 258 + A VMG+EG+GMRRLTRE CD+LV+IPMFG+VES+NVSV++G+ L E RRQR+ K Sbjct: 187 NLPDSAAWVMGNEGDGMRRLTREHCDMLVSIPMFGTVESMNVSVSAGMVLSETRRQRVLK 246 >yjfH [J] COG0566 rRNA methylases Eco Escherichia coli K12 Length = 243 Score = 251 bits (640), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 130/242 (53%), Positives = 166/242 (68%), Gaps = 3/242 (1%) Query: 16 SKMIFGFHAVTSRIRHEASSVDEIYVDAERRDRRMLDLLHAAKEANVRIIQADDQRLAAM 75 S+MI+G HAV + + E+++ R D+R+L L+HA + V I A+ Q L Sbjct: 2 SEMIYGIHAVQALLERAPERFQEVFILKGREDKRLLPLIHALESQGVVIQLANRQYLDEK 61 Query: 76 VGTRRHQGVVA--KAAALSLARTLDELLDAVVGPPLLLILDGITDPHNLGACLRVADGAG 133 HQG++A K L +L+ A + P LLILDG+TDPHNLGACLR AD AG Sbjct: 62 SDGAVHQGIIARVKPGRQYQENDLPDLI-ASLDQPFLLILDGVTDPHNLGACLRSADAAG 120 Query: 134 AHAVIAPKDRAVGLNATAMKVSSGASDTVPYITVTNLARTMRDLKERGVWIIGTSDDAEK 193 HAVI PKDR+ LNATA KV+ GA+++VP I VTNLARTMR L+E +WI+GT+ +A+ Sbjct: 121 VHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLARTMRMLQEENIWIVGTAGEADH 180 Query: 194 GLYEGDFTGPTALVMGSEGEGMRRLTRETCDVLVNIPMFGSVESLNVSVASGVCLYEARR 253 LY+ TG ALVMG+EGEGMRRLTRE CD L++IPM GSV SLNVSVA+G+CL+EA R Sbjct: 181 TLYQSKMTGRLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLFEAVR 240 Query: 254 QR 255 QR Sbjct: 241 QR 242 >ZyjfH [J] COG0566 rRNA methylases EcZ Escherichia coli O157:H7 EDL933 Length = 243 Score = 251 bits (640), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 130/242 (53%), Positives = 166/242 (68%), Gaps = 3/242 (1%) Query: 16 SKMIFGFHAVTSRIRHEASSVDEIYVDAERRDRRMLDLLHAAKEANVRIIQADDQRLAAM 75 S+MI+G HAV + + E+++ R D+R+L L+HA + V I A+ Q L Sbjct: 2 SEMIYGIHAVQALLERAPERFQEVFILKGREDKRLLPLIHALESQGVVIQLANRQYLDEK 61 Query: 76 VGTRRHQGVVA--KAAALSLARTLDELLDAVVGPPLLLILDGITDPHNLGACLRVADGAG 133 HQG++A K L +L+ A + P LLILDG+TDPHNLGACLR AD AG Sbjct: 62 SDGAVHQGIIARVKPGRQYQENDLPDLI-ASLDQPFLLILDGVTDPHNLGACLRSADAAG 120 Query: 134 AHAVIAPKDRAVGLNATAMKVSSGASDTVPYITVTNLARTMRDLKERGVWIIGTSDDAEK 193 HAVI PKDR+ LNATA KV+ GA+++VP I VTNLARTMR L+E +WI+GT+ +A+ Sbjct: 121 VHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLARTMRMLQEENIWIVGTAGEADH 180 Query: 194 GLYEGDFTGPTALVMGSEGEGMRRLTRETCDVLVNIPMFGSVESLNVSVASGVCLYEARR 253 LY+ TG ALVMG+EGEGMRRLTRE CD L++IPM GSV SLNVSVA+G+CL+EA R Sbjct: 181 TLYQSKMTGRLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLFEAVR 240 Query: 254 QR 255 QR Sbjct: 241 QR 242 >ECs5156 [J] COG0566 rRNA methylases Ecs Escherichia coli O157:H7 Length = 243 Score = 251 bits (640), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 130/242 (53%), Positives = 166/242 (68%), Gaps = 3/242 (1%) Query: 16 SKMIFGFHAVTSRIRHEASSVDEIYVDAERRDRRMLDLLHAAKEANVRIIQADDQRLAAM 75 S+MI+G HAV + + E+++ R D+R+L L+HA + V I A+ Q L Sbjct: 2 SEMIYGIHAVQALLERAPERFQEVFILKGREDKRLLPLIHALESQGVVIQLANRQYLDEK 61 Query: 76 VGTRRHQGVVA--KAAALSLARTLDELLDAVVGPPLLLILDGITDPHNLGACLRVADGAG 133 HQG++A K L +L+ A + P LLILDG+TDPHNLGACLR AD AG Sbjct: 62 SDGAVHQGIIARVKPGRQYQENDLPDLI-ASLDQPFLLILDGVTDPHNLGACLRSADAAG 120 Query: 134 AHAVIAPKDRAVGLNATAMKVSSGASDTVPYITVTNLARTMRDLKERGVWIIGTSDDAEK 193 HAVI PKDR+ LNATA KV+ GA+++VP I VTNLARTMR L+E +WI+GT+ +A+ Sbjct: 121 VHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLARTMRMLQEENIWIVGTAGEADH 180 Query: 194 GLYEGDFTGPTALVMGSEGEGMRRLTRETCDVLVNIPMFGSVESLNVSVASGVCLYEARR 253 LY+ TG ALVMG+EGEGMRRLTRE CD L++IPM GSV SLNVSVA+G+CL+EA R Sbjct: 181 TLYQSKMTGRLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLFEAVR 240 Query: 254 QR 255 QR Sbjct: 241 QR 242 >STM4369 [J] COG0566 rRNA methylases Sty Salmonella typhimurium LT2 Length = 243 Score = 248 bits (632), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 129/242 (53%), Positives = 165/242 (68%), Gaps = 3/242 (1%) Query: 16 SKMIFGFHAVTSRIRHEASSVDEIYVDAERRDRRMLDLLHAAKEANVRIIQADDQRLAAM 75 S+MI+G HAV + + E+++ R D+R+L L+HA + V I A+ Q L Sbjct: 2 SEMIYGIHAVQALLERAPERFQEVFILKGREDKRLLPLIHALESQGVVIQLANRQYLDEK 61 Query: 76 VGTRRHQGVVA--KAAALSLARTLDELLDAVVGPPLLLILDGITDPHNLGACLRVADGAG 133 HQG++A K L +L+ A+ P LLILDG+TDPHNLGACLR AD AG Sbjct: 62 SDGAVHQGIIARVKPGRQYQENDLPDLI-ALHDRPFLLILDGVTDPHNLGACLRSADAAG 120 Query: 134 AHAVIAPKDRAVGLNATAMKVSSGASDTVPYITVTNLARTMRDLKERGVWIIGTSDDAEK 193 HAVI PKDR+ LNATA KV+ GA+++VP I VTNLARTMR L+E +WI+GT+ +A+ Sbjct: 121 VHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLARTMRMLQEENIWIVGTAGEADH 180 Query: 194 GLYEGDFTGPTALVMGSEGEGMRRLTRETCDVLVNIPMFGSVESLNVSVASGVCLYEARR 253 LY+ G ALVMG+EGEGMRRLTRE CD L++IPM GSV SLNVSVA+G+CL+EA R Sbjct: 181 TLYQSKMPGRMALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLFEAVR 240 Query: 254 QR 255 QR Sbjct: 241 QR 242 >YPO0381 [J] COG0566 rRNA methylases Ype Yersinia pestis Length = 246 Score = 243 bits (621), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 128/242 (52%), Positives = 165/242 (68%), Gaps = 3/242 (1%) Query: 16 SKMIFGFHAVTSRIRHEASSVDEIYVDAERRDRRMLDLLHAAKEANVRIIQADDQRLAAM 75 S++I+G HAV + + + E+++ R DRR+ L+ + A + I A Q L + Sbjct: 2 SEIIYGIHAVKALLERDPQRFLEVFILKGRDDRRLQPLIAELEAAGLVIQVASRQWLDSQ 61 Query: 76 VGTRRHQGVVAKA--AALSLARTLDELLDAVVGPPLLLILDGITDPHNLGACLRVADGAG 133 V HQG+VA+ L LL++V P LL+LDG+TDPHNLGACLR AD AG Sbjct: 62 VEGGVHQGIVARVREGRQYQENDLPALLESV-ETPFLLVLDGVTDPHNLGACLRSADAAG 120 Query: 134 AHAVIAPKDRAVGLNATAMKVSSGASDTVPYITVTNLARTMRDLKERGVWIIGTSDDAEK 193 HAVI P+DR+ LNA A KV+SGA++ VP I VTNLART+R L+E VWI+GT+ +A+ Sbjct: 121 VHAVIVPRDRSAQLNAIAKKVASGAAENVPLIKVTNLARTLRVLQEHNVWIVGTAGEADH 180 Query: 194 GLYEGDFTGPTALVMGSEGEGMRRLTRETCDVLVNIPMFGSVESLNVSVASGVCLYEARR 253 LY+ TGP ALVMG+EGEGMRRLTRE CD L++IPM GSV SLNVSVA+GVCL+E R Sbjct: 181 TLYQSKMTGPMALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGVCLFEVVR 240 Query: 254 QR 255 QR Sbjct: 241 QR 242 >PA4936 [J] COG0566 rRNA methylases Pae Pseudomonas aeruginosa Length = 248 Score = 241 bits (615), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 122/245 (49%), Positives = 164/245 (66%), Gaps = 3/245 (1%) Query: 15 KSKMIFGFHAVTSRIRHEASSVDEIYVDAERRDRRMLDLLHAAKEANVRIIQADDQRLAA 74 + + ++G HAV + +RH V ++++ R D R+ L A + + Q D + L Sbjct: 3 QWEKVYGVHAVEALLRHHPKRVKQLWLAEGRHDPRVQVLTELAAGFRIPVGQRDRRELDE 62 Query: 75 MVGTRRHQGVVAKAAALSL--ARTLDELLDAVVGPPLLLILDGITDPHNLGACLRVADGA 132 HQGVVA+ + + L+ELL+ G PLLL LDG+TDPHNLGACLR AD A Sbjct: 63 W-AEGVHQGVVAEVSPSQVWGENMLEELLERSEGVPLLLALDGVTDPHNLGACLRTADAA 121 Query: 133 GAHAVIAPKDRAVGLNATAMKVSSGASDTVPYITVTNLARTMRDLKERGVWIIGTSDDAE 192 G AVI PKD++ LNAT KV+ GA++ +P + VTNLART+ L++RG+W++GT+ +A+ Sbjct: 122 GVQAVIVPKDKSATLNATVRKVACGAAEVIPLVAVTNLARTLEKLQQRGLWVVGTAGEAD 181 Query: 193 KGLYEGDFTGPTALVMGSEGEGMRRLTRETCDVLVNIPMFGSVESLNVSVASGVCLYEAR 252 K LY+ D GPT LVMG+EG+GMRRLTRE CD L +PM GSV SLNVSVA+GVCL+E Sbjct: 182 KTLYQLDLKGPTVLVMGAEGKGMRRLTREHCDFLARLPMAGSVSSLNVSVATGVCLFEIL 241 Query: 253 RQRLP 257 RQR P Sbjct: 242 RQRTP 246 >HI0860 [J] COG0566 rRNA methylases Hin Haemophilus influenzae Length = 246 Score = 240 bits (613), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 127/244 (52%), Positives = 167/244 (68%), Gaps = 4/244 (1%) Query: 16 SKMIFGFHAVTSRIRHEASSVDEIYVDAERRDRRMLDLLHAAKEANVRIIQADDQRLAAM 75 S+ I+G HAV S + H + E++V R D+R+ LL+ + + + Q L Sbjct: 2 SEQIYGIHAVNSILTHSPERLIEVFVLKGREDKRLQPLLNELYSLGIGVQFVNRQTLDKK 61 Query: 76 VGTRRHQGVVAKA-AALSLART-LDELLDAVVGPPLLLILDGITDPHNLGACLRVADGAG 133 HQGV+A+ AA L LDE+L A PLLL+LDG+TDPHNLGACLR AD AG Sbjct: 62 ADGEVHQGVIARVQAAKELNENDLDEIL-ANKQNPLLLVLDGVTDPHNLGACLRTADAAG 120 Query: 134 AHAVIAPKDRAVGLNATAMKVSSGASDTVPYITVTNLARTMRDLKER-GVWIIGTSDDAE 192 A AVI PKD++ L + A KV+ GA++TVP I VTNL+RT+RDL++ +W++GT+ +A Sbjct: 121 AVAVIVPKDKSAQLTSIARKVACGAAETVPLIRVTNLSRTLRDLQQNHNIWVVGTAGEAT 180 Query: 193 KGLYEGDFTGPTALVMGSEGEGMRRLTRETCDVLVNIPMFGSVESLNVSVASGVCLYEAR 252 + +Y+ TGP ALVMG+EGEGMRRLTRE CD L++IPM GSV SLNVSVA+GVCL+E Sbjct: 181 ETIYQSKLTGPLALVMGAEGEGMRRLTREHCDQLISIPMAGSVSSLNVSVATGVCLFEIV 240 Query: 253 RQRL 256 RQRL Sbjct: 241 RQRL 244