BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0032.p (311 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2115 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 233 5e-61 SMa0498 [K] COG0583 Transcriptional regulator Sme Sinorhizobium ... 113 5e-25 YPO1934 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 113 7e-25 PA2497 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 98 3e-20 BS_ywbI [K] COG0583 Transcriptional regulator Bsu Bacillus subtilis 94 5e-19 RSc1094 [K] COG0583 Transcriptional regulator Rso Ralstonia sola... 92 1e-18 mll6897 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium ... 89 1e-17 YPO3915 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 87 3e-17 oxyR [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 87 4e-17 ZoxyR [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 87 4e-17 >PA2115 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 317 Score = 233 bits (593), Expect = 5e-61, Method: Compositional matrix adjust. Identities = 130/312 (41%), Positives = 197/312 (63%), Gaps = 5/312 (1%) Query: 1 MNIRFLETFVWLARLRNFRLTAERLHTTQAAVSSRIASLEQDFGVRLFDRSAREVALTAD 60 MN++FLETFVW+ARL++FRLTAE+L +TQA++SSRIA LE + GV+LF R +R V LT + Sbjct: 1 MNLKFLETFVWVARLKSFRLTAEKLFSTQASISSRIAVLEDELGVKLFVRDSRGVTLTPE 60 Query: 61 GSKALVHAERMVKLMREMKEDMSDREVYAGVIRIGVIESIVHSWFPDFLGRLHKTFPRLQ 120 G K L +AERM+ M +K+ + G IRIG +++++H+W + R+ +TFP ++ Sbjct: 61 GDKVLAYAERMMDTMHALKQSLDTGASTQGRIRIGAMDTVIHTWLSPLVARVTETFPAVE 120 Query: 121 IEIVSDTTIHLHEQFSKGNLDLVLQAEAVIGPQVSNLALCEFPMRWVGSPKLDIGSETLS 180 IE+++DT +L EQ KG LDL+ Q +++ V NL L +P+RW+ S + S Sbjct: 121 IELMADTARNLSEQLQKGYLDLIFQTDSLRHESVLNLELGSYPLRWIVSTGSIYHRDYAS 180 Query: 181 LADLAAFPIISFARNSGPHA-VIERLFSDSQRSERTLHINCIASVATMIRLATDGFGITA 239 LADLA +++F+++S PH V+ L ++ + R +NC+ SVA M RL DGFG+ A Sbjct: 181 LADLARERVVTFSKHSRPHQDVLGLLHANGVAAPR---LNCVNSVAAMTRLLRDGFGVGA 237 Query: 240 VPPAIIQRELNEESLHLLRVDTEFPALVLIASFRSDHENPLTETVARIAQETAADFALNW 299 +PPA++ +EL L LLR+ P L ++ S+R L + V +++ AD+A N Sbjct: 238 LPPALVSQELERGELTLLRLGPPPPNLPVVVSWRGGTGLELVDEVVELSKAVLADYAANV 297 Query: 300 GHEIARLPAPLN 311 G E L APL Sbjct: 298 GPECMLL-APLK 308 >SMa0498 [K] COG0583 Transcriptional regulator Sme Sinorhizobium meliloti Length = 299 Score = 113 bits (283), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 78/270 (28%), Positives = 135/270 (50%), Gaps = 12/270 (4%) Query: 1 MNIRF--LETFVWLARLRNFRLTAERLHTTQAAVSSRIASLEQDFGVRLFDRSAREVALT 58 M + F LE+F W+++LR+F A +L+ +Q VS RI LE+ GV LF R R++ LT Sbjct: 1 MTLSFSALESFYWVSQLRSFNAAANKLNVSQPTVSYRIRELEERLGVSLFVRQRRQLVLT 60 Query: 59 ADGSKALVHAERMVKLMREMKEDMSDREVYAGVIRIGVIESIVHSWFPDFLGRLHKTFPR 118 ++G +AE M+ + R+++ ++ R +R+GVI+S P L L F Sbjct: 61 SEGEALKHYAESMIAIARDIESNIKTRNTRLPTLRVGVIDSFAAVCLPSLLDELDIRFAG 120 Query: 119 LQIEIVSDTTIHLHEQFSKGNLDLVLQAEAVIGPQVSNLALCEFPMR----WVGSPKLDI 174 +I DT+ L +Q S+G LD+ + + P N+AL E R W+ S KL + Sbjct: 121 ARIAATVDTSHKLADQLSEGLLDIAVLSTP---PSHDNVAL-ELLGRQSVDWIASHKLGL 176 Query: 175 GSETLSLADLAAFPIISFARNSGPHAVIERLFSDSQRSERTLHINCIASVATMIRLATDG 234 +S +L I + S H++ + + + L +N S+ T++ L G Sbjct: 177 PQTIVSDEELLRQRIFATPAPSNLHSLTTGFLAATAGA--GLRLNVCNSLGTILNLVESG 234 Query: 235 FGITAVPPAIIQRELNEESLHLLRVDTEFP 264 GI+ +P ++Q ++ ++ +L+ T P Sbjct: 235 TGISILPSRLLQEQIRHGTIQVLKTRTTLP 264 >YPO1934 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 320 Score = 113 bits (282), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 88/315 (27%), Positives = 140/315 (44%), Gaps = 18/315 (5%) Query: 1 MNIRFLETFVWLARLRNFRLTAERLHTTQAAVSSRIASLEQDFGVRLFDRSAREVALTAD 60 M ++ LE F W AR NF + AERLH + +++S RI LE G LFDRS LT Sbjct: 1 MTLKQLEAFYWAARCSNFSIAAERLHISISSLSKRIVELEASLGCTLFDRSGYRAVLTET 60 Query: 61 GSKALVHAERMVKLMREMKEDMSDREVYAGVIRIGVIESIVHSWFPDFLGRLHKTFPRLQ 120 G L A +++ E++ + E +G+ GV E +W P F+ +P+L Sbjct: 61 GQNLLPRAFALLESAAEIRNTLGASEGLSGICNFGVGELSALTWLPSFIASARLLYPKLL 120 Query: 121 IEIVSDTTIHLHEQFSKGNLDLVLQAEAVIGPQVSNLALCEFPMRWVGSPKLDIGSETLS 180 + D L + +KG +D + A + +L + + W+ SP L + T+ Sbjct: 121 LAPHVDVGAALEGRVNKGEMDFAIIAGRSSRQNILSLPIAQAQFVWMASPTL---ANTVG 177 Query: 181 LADLA---AFPIISFARNSGPHAVIER-LFSDSQRSERTLHINCIASVATMIRLATDGFG 236 AD A A P+I+ +G +I+ L + S ++ N ++ M+ +A+ G G Sbjct: 178 TADSALRQALPLITLPPGAGSSRIIDAWLMAYGIASVARINCNSWGAIVGML-IASVGIG 236 Query: 237 ITAVPPAIIQRELNEESLHLLRVDTEFPALVLIASFRSDHENPLTETVARIAQETAADFA 296 I +P + ++ L L AL +R D PL + R+ ADF+ Sbjct: 237 I--LPTSWAEKLSLHNQLEYLPCSEPLAALNYSFQWRRDDPRPLIRKM-RVLVADLADFS 293 Query: 297 LNWGHEIARLPAPLN 311 LN P PLN Sbjct: 294 LN-------SPLPLN 301 >PA2497 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 292 Score = 97.8 bits (242), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 76/251 (30%), Positives = 117/251 (46%), Gaps = 15/251 (5%) Query: 1 MNIRFLETFVWLARLRNFRLTAERLHTTQAAVSSRIASLEQDFGVRLFDRSAREVALTAD 60 +++ L TFV + NF E LH TQ+ VS ++ LEQ+ G RL DRS R+V T + Sbjct: 2 LDLVLLRTFVSVVDTGNFTRAGEHLHLTQSTVSQQVIRLEQNLGCRLLDRSQRQVLPTEE 61 Query: 61 GSKALVHAERMVKLMREMKEDMSDREVYAGVIRIGVIESIVHSWFPDFLGRLHKTFPRLQ 120 G + L +A R+++L E E +S GV+R+GV E + L R + PRL+ Sbjct: 62 GERLLGYARRLLRLSDEASEALSPAH-GDGVLRLGVPEDLAGEVLMPVLTRFTEERPRLR 120 Query: 121 IEIVSDTTIHLHEQFSKGNLDLVLQAEAVIGPQVSNLALCEFPMRWVGSPKLDIGSETL- 179 +E+ S + HL + G LDL+L + G A P+ W GS G + Sbjct: 121 LEVESGLSHHLLRLYRSGELDLLLVKQ--WGADSDCHARWAEPLGWFGSAARPFGEGSPE 178 Query: 180 SLADLAAFPIISFARNSGPHAV--IERLFSDSQRSERTLHINCIASVATMIRLATDGFGI 237 L FP+ + R HA+ I R + S AS+A+++ G G+ Sbjct: 179 EPVPLVVFPVGALYRQEMIHALESIGRRWRIGYSS---------ASLASLVAAVGAGLGV 229 Query: 238 TAVPPAIIQRE 248 + +P + E Sbjct: 230 SLLPLGCVGPE 240 >BS_ywbI [K] COG0583 Transcriptional regulator Bsu Bacillus subtilis Length = 301 Score = 93.6 bits (231), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 47/143 (32%), Positives = 83/143 (58%), Gaps = 1/143 (0%) Query: 1 MNIRFLETFVWLARLRNFRLTAERLHTTQAAVSSRIASLEQDFGVRLFDRSAREVALTAD 60 M+IR L F+ +ARL++F ++ L+ +Q +S I +LE++ G+ LF R+ R+V LT Sbjct: 1 MDIRHLTYFLEVARLKSFTKASQSLYVSQPTISKMIKNLEEELGIELFYRNGRQVELTDA 60 Query: 61 GSKALVHAERMVKLMREMKEDMSD-REVYAGVIRIGVIESIVHSWFPDFLGRLHKTFPRL 119 G V A+ ++K + + +++D EV G +RIG+ I +FP LG + +P + Sbjct: 61 GHSMYVQAQEIIKSFQNLTSELNDIMEVKKGHVRIGLPPMIGSGFFPRVLGDFRENYPNV 120 Query: 120 QIEIVSDTTIHLHEQFSKGNLDL 142 ++V D +I + E G+LD+ Sbjct: 121 TFQLVEDGSIKVQEGVGDGSLDI 143 >RSc1094 [K] COG0583 Transcriptional regulator Rso Ralstonia solanacearum Length = 311 Score = 92.0 bits (227), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 50/149 (33%), Positives = 83/149 (55%) Query: 1 MNIRFLETFVWLARLRNFRLTAERLHTTQAAVSSRIASLEQDFGVRLFDRSAREVALTAD 60 M++R L T V + F E + TQ+AVS ++ +LE +FGVRLFDRS R+ ALT Sbjct: 13 MSLRALRTLVAIVHHGTFARAGEAIGLTQSAVSLQVKALEDEFGVRLFDRSRRQPALTEA 72 Query: 61 GSKALVHAERMVKLMREMKEDMSDREVYAGVIRIGVIESIVHSWFPDFLGRLHKTFPRLQ 120 G L AE+++ L + + +SD + G +RIG I++ + PD L L + P L+ Sbjct: 73 GRIVLAQAEQILALYDHIPDSLSDEKALVGRLRIGAIQTALSGPLPDALLALRRDHPLLR 132 Query: 121 IEIVSDTTIHLHEQFSKGNLDLVLQAEAV 149 + + + + L ++ + G LD + ++ V Sbjct: 133 VHVAAGMSAELAQRVAAGELDAAITSQPV 161 >mll6897 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium loti Length = 320 Score = 89.4 bits (220), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 48/144 (33%), Positives = 81/144 (56%), Gaps = 1/144 (0%) Query: 1 MNIRFLETFVWLARLRNFRLTAERLHTTQAAVSSRIASLEQDFGVRLFDRSAREVALTAD 60 +++ L+TF+ +A +F AE +H TQ+AVS ++ LE+ G LF++ R LT + Sbjct: 7 LDLDQLQTFISIADTGSFTRAAEEVHRTQSAVSMQMRRLEERIGKPLFEKEGRSNRLTEE 66 Query: 61 GSKALVHAERMVKLMREMKEDMSDREVYAGVIRIGVIESIVHSWFPDFLGRLHKTFPRLQ 120 G K L +A R++ L RE D+ + G IRIG + + P+ + R ++ PR++ Sbjct: 67 GDKLLSYARRLLYLNRETLAAFDDQRL-EGTIRIGTPDDYADRFLPEIMARFTRSNPRVE 125 Query: 121 IEIVSDTTIHLHEQFSKGNLDLVL 144 + ++ + T L E +GNLDL L Sbjct: 126 LTVICEPTPGLVEHIKRGNLDLAL 149 >YPO3915 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 305 Score = 87.4 bits (215), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 54/156 (34%), Positives = 85/156 (54%), Gaps = 6/156 (3%) Query: 1 MNIRFLETFVWLARLRNFRLTAERLHTTQAAVSSRIASLEQDFGVRLFDRSAREVALTAD 60 MNIR LE V LA R+FR A+ H +Q +S +I LE + G+ L +R++R+V T Sbjct: 1 MNIRDLEYLVALAEFRHFRRAADSCHVSQPTLSGQIRKLEDELGIMLLERTSRKVLFTQA 60 Query: 61 GSKALVHAERMVKLMREMKEDMS-DREVYAGVIRIGVIESIVHSWFPDFLGRLHKTFPRL 119 G + A+ +++ ++ +KE S E +G + IG+I ++ P + LHKTFP+L Sbjct: 61 GLLLVEQAKTVLREVKVLKEMASLQGESMSGPLHIGLIPTVGPYLLPQIIPMLHKTFPKL 120 Query: 120 QIEIVSDTTIHLHEQFSKGNLD-----LVLQAEAVI 150 ++ + T +L Q G LD LV + EA I Sbjct: 121 EMYLHEAQTQNLLAQLDSGKLDCAILALVKETEAFI 156 >oxyR [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 305 Score = 87.4 bits (215), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 53/149 (35%), Positives = 79/149 (53%), Gaps = 5/149 (3%) Query: 1 MNIRFLETFVWLARLRNFRLTAERLHTTQAAVSSRIASLEQDFGVRLFDRSAREVALTAD 60 MNIR LE V LA R+FR A+ H +Q +S +I LE + GV L +R++R+V T Sbjct: 1 MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELGVMLLERTSRKVLFTQA 60 Query: 61 GSKALVHAE---RMVKLMREMKEDMSDREVYAGVIRIGVIESIVHSWFPDFLGRLHKTFP 117 G + A R VK+++EM E +G + IG+I ++ P + LH+TFP Sbjct: 61 GMLLVDQARTVLREVKVLKEMASQQG--ETMSGPLHIGLIPTVGPYLLPHIIPMLHQTFP 118 Query: 118 RLQIEIVSDTTIHLHEQFSKGNLDLVLQA 146 +L++ + T L Q G LD V+ A Sbjct: 119 KLEMYLHEAQTHQLLAQLDSGKLDCVILA 147 >ZoxyR [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 305 Score = 87.4 bits (215), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 53/149 (35%), Positives = 79/149 (53%), Gaps = 5/149 (3%) Query: 1 MNIRFLETFVWLARLRNFRLTAERLHTTQAAVSSRIASLEQDFGVRLFDRSAREVALTAD 60 MNIR LE V LA R+FR A+ H +Q +S +I LE + GV L +R++R+V T Sbjct: 1 MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELGVMLLERTSRKVLFTQA 60 Query: 61 GSKALVHAE---RMVKLMREMKEDMSDREVYAGVIRIGVIESIVHSWFPDFLGRLHKTFP 117 G + A R VK+++EM E +G + IG+I ++ P + LH+TFP Sbjct: 61 GMLLVDQARTVLREVKVLKEMASQQG--ETMSGPLHIGLIPTVGPYLLPHIIPMLHQTFP 118 Query: 118 RLQIEIVSDTTIHLHEQFSKGNLDLVLQA 146 +L++ + T L Q G LD V+ A Sbjct: 119 KLEMYLHEAQTHQLLAQLDSGKLDCVILA 147