BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0031.p (437 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 187 4e-47 YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 168 3e-41 BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 164 5e-40 RSp1572 [GEPR] COG0477 Permeases of the major facilitator superf... 155 1e-37 RSp0182 [GEPR] COG0477 Permeases of the major facilitator superf... 146 1e-34 AGc4908 [GEPR] COG0477 Permeases of the major facilitator superf... 144 3e-34 PA4126 [GEPR] COG0477 Permeases of the major facilitator superfa... 142 2e-33 Cj0484 [GEPR] COG0477 Permeases of the major facilitator superfa... 132 2e-30 CC2354 [GEPR] COG0477 Permeases of the major facilitator superfa... 130 6e-30 PA2214 [GEPR] COG0477 Permeases of the major facilitator superfa... 125 2e-28 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 187 bits (475), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 90/135 (66%), Positives = 108/135 (80%), Gaps = 2/135 (1%) Query: 4 SPSAAATPAAHASAAAPLEVTYRKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQF 63 PSA A P AS E TYRK++WRLIPFL+ +V+A++DRVNVGFAKLQML DL+F Sbjct: 9 GPSAGALPPQSASGFE--EATYRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLNDLKF 66 Query: 64 SEAVYGLGAGIFFIGYFIFEVPSNLLLEKIGARKTLARITILWGLASMAMAYVTTPTSFY 123 SE VYGLGAGIFFIGYF+FEVPSN++L ++GAR +ARI I WGL S AM +VTTP FY Sbjct: 67 SETVYGLGAGIFFIGYFLFEVPSNVILHRVGARMWIARIMISWGLISAAMMFVTTPAMFY 126 Query: 124 ILRFLLGIFEAGFFP 138 ++RFLLG+ EAGFFP Sbjct: 127 VMRFLLGLAEAGFFP 141 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 168 bits (425), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 75/114 (65%), Positives = 92/114 (80%) Query: 25 YRKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQFSEAVYGLGAGIFFIGYFIFEV 84 YRK W L+P L+ +VL ++DRVNVGFAKLQM DLQFS+ VYGLGAG+FFIGYF E+ Sbjct: 22 YRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDLQFSDTVYGLGAGMFFIGYFFLEI 81 Query: 85 PSNLLLEKIGARKTLARITILWGLASMAMAYVTTPTSFYILRFLLGIFEAGFFP 138 PSNL+L ++GAR +ARI I WG+ S MA+VTTP SFY++RFLLG+ EAGFFP Sbjct: 82 PSNLILHRVGARLWIARIMITWGIISACMAFVTTPMSFYVMRFLLGVAEAGFFP 135 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 164 bits (414), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 75/117 (64%), Positives = 95/117 (81%) Query: 22 EVTYRKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQFSEAVYGLGAGIFFIGYFI 81 +TYRK+A+R+IP L+ +++A++DRVNVGFAKLQM ++L FSEA+YGLGAG+FFIGYF Sbjct: 34 NMTYRKVAFRIIPLLMICYIIAYLDRVNVGFAKLQMSEELGFSEAIYGLGAGLFFIGYFF 93 Query: 82 FEVPSNLLLEKIGARKTLARITILWGLASMAMAYVTTPTSFYILRFLLGIFEAGFFP 138 FE+PSN+LL K+GAR +ARI I WGL S A+V T FYILRFLLG EAGF+P Sbjct: 94 FEIPSNILLHKLGARLWIARIMITWGLLSALFAFVQTEWQFYILRFLLGAAEAGFYP 150 >RSp1572 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 155 bits (393), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 71/115 (61%), Positives = 89/115 (77%) Query: 24 TYRKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQFSEAVYGLGAGIFFIGYFIFE 83 Y + R++PFL ++ A++DR+N+GFAKLQM DL S+A YGLGAGIFF GY +FE Sbjct: 19 VYSVVNRRILPFLATCYLFAYLDRINIGFAKLQMQNDLALSDAAYGLGAGIFFFGYMLFE 78 Query: 84 VPSNLLLEKIGARKTLARITILWGLASMAMAYVTTPTSFYILRFLLGIFEAGFFP 138 VPSNLLL KIGAR+TL+RI ILWG+ S +M +VT +FY LRFLLG+FEAGF P Sbjct: 79 VPSNLLLVKIGARRTLSRILILWGIVSASMLFVTDVWTFYALRFLLGVFEAGFAP 133 >RSp0182 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 453 Score = 146 bits (368), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 72/143 (50%), Positives = 100/143 (69%), Gaps = 5/143 (3%) Query: 1 MSYSPSAAATPAAHASAA----APLE-VTYRKIAWRLIPFLVFLFVLAWIDRVNVGFAKL 55 MS++ ++A PA AA AP E RKI WR++PF+ L++++++DR N+G+A L Sbjct: 1 MSHTQASAGAPAVGTIAARHPAAPDERAIVRKITWRILPFVFALYIISYLDRANIGYAAL 60 Query: 56 QMLQDLQFSEAVYGLGAGIFFIGYFIFEVPSNLLLEKIGARKTLARITILWGLASMAMAY 115 QM Q+L S +G +GIFFIGYF+FEVPSNL+L + GAR+ +ARI + WGL +M A+ Sbjct: 61 QMNQELALSSEAFGFVSGIFFIGYFLFEVPSNLMLNRFGARRWIARILVTWGLVAMGSAF 120 Query: 116 VTTPTSFYILRFLLGIFEAGFFP 138 V + T Y LRFLLG+ EAGFFP Sbjct: 121 VQSATQLYALRFLLGVAEAGFFP 143 >AGc4908 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 487 Score = 144 bits (364), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 69/112 (61%), Positives = 84/112 (75%) Query: 27 KIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQFSEAVYGLGAGIFFIGYFIFEVPS 86 KI WRL+PFL L+++A+IDR NV +AKLQM+ L SE YGLGA +FFIGYF+FEVPS Sbjct: 72 KITWRLMPFLGLLYLIAYIDRQNVSYAKLQMVDALSLSEYAYGLGASLFFIGYFLFEVPS 131 Query: 87 NLLLEKIGARKTLARITILWGLASMAMAYVTTPTSFYILRFLLGIFEAGFFP 138 NL L + GA K ARI + WG ++A+AY T FYILRFLLG+ EAGFFP Sbjct: 132 NLFLNRFGASKWFARILVSWGAVTIALAYTQNATMFYILRFLLGLCEAGFFP 183 >PA4126 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 434 Score = 142 bits (357), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 65/117 (55%), Positives = 88/117 (75%) Query: 22 EVTYRKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQFSEAVYGLGAGIFFIGYFI 81 + T+ ++ WRL+P L+ +V A +DR+N+GFAKLQM DL FS+ VYGLGAG+FFI Y + Sbjct: 16 DSTHDRVTWRLMPLLLVCYVFAHLDRINIGFAKLQMSADLHFSDTVYGLGAGLFFIAYAL 75 Query: 82 FEVPSNLLLEKIGARKTLARITILWGLASMAMAYVTTPTSFYILRFLLGIFEAGFFP 138 F +PSNL+LE+IG R+ +A + ++WG S AM V T FY+LRFLLG+ EAGFFP Sbjct: 76 FGLPSNLMLERIGPRRWIACLMLVWGCLSTAMLLVETARGFYLLRFLLGVAEAGFFP 132 >Cj0484 [GEPR] COG0477 Permeases of the major facilitator superfamily Cje Campylobacter jejuni Length = 410 Score = 132 bits (332), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 66/123 (53%), Positives = 87/123 (70%), Gaps = 1/123 (0%) Query: 14 HASAAAPLEVTYRKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQFSEAVYGLGAG 73 HA++ LE+ +KI+WR++P +V +F L+ +DR N+ F K + D EA Y LGAG Sbjct: 3 HANSI-KLELVCKKISWRILPLIVLMFCLSMLDRTNISFVKSHIEIDAGIGEAAYALGAG 61 Query: 74 IFFIGYFIFEVPSNLLLEKIGARKTLARITILWGLASMAMAYVTTPTSFYILRFLLGIFE 133 IFFIGY IFEVPSNL L K+GA+ L+RI I WGL +MAM ++ SFY+LRFLLG+ E Sbjct: 62 IFFIGYAIFEVPSNLFLHKLGAKIWLSRIMITWGLVTMAMIFIQGEISFYVLRFLLGLTE 121 Query: 134 AGF 136 AGF Sbjct: 122 AGF 124 >CC2354 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 430 Score = 130 bits (327), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 59/115 (51%), Positives = 81/115 (70%) Query: 24 TYRKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQFSEAVYGLGAGIFFIGYFIFE 83 T ++ RL+P ++++A+IDR NV +AKL M+ L SEA YGLGA +FFIGYF+FE Sbjct: 12 TVGRVTRRLMPLFCLMYLIAYIDRQNVSYAKLDMVSALGLSEAAYGLGASLFFIGYFLFE 71 Query: 84 VPSNLLLEKIGARKTLARITILWGLASMAMAYVTTPTSFYILRFLLGIFEAGFFP 138 P+NL+L ++GAR ARI WGL ++A+ + FY+LRFLLG+ EAGFFP Sbjct: 72 APANLILARVGARVWFARIMFSWGLVTLALGFTQNAAMFYVLRFLLGVAEAGFFP 126 >PA2214 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 440 Score = 125 bits (314), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 60/108 (55%), Positives = 77/108 (71%) Query: 31 RLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQFSEAVYGLGAGIFFIGYFIFEVPSNLLL 90 RL+PFLV ++VLA+IDR NVG+A+ + D +A + GA IFFIGY FEVPSNL+L Sbjct: 21 RLLPFLVLMYVLAFIDRANVGYARAFLQADTGLGDAAFAFGASIFFIGYACFEVPSNLML 80 Query: 91 EKIGARKTLARITILWGLASMAMAYVTTPTSFYILRFLLGIFEAGFFP 138 ++GAR L RI + WGL S AM + +FY+LRFLLG+ EAGFFP Sbjct: 81 HRLGARVWLCRIMVTWGLVSAAMMFADDAMTFYVLRFLLGVAEAGFFP 128