BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0005.p (322 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0987 [GER] COG0697 Permeases of the drug/metabolite transport... 288 8e-78 SMb20040 [GER] COG0697 Permeases of the drug/metabolite transpor... 239 5e-63 AGc394 [GER] COG0697 Permeases of the drug/metabolite transporte... 222 7e-58 BS_ydeK [GER] COG0697 Permeases of the drug/metabolite transport... 218 2e-56 mll1137 [GER] COG0697 Permeases of the drug/metabolite transport... 217 2e-56 BMEI0170 [GER] COG0697 Permeases of the drug/metabolite transpor... 206 8e-53 >RSc0987 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 313 Score = 288 bits (738), Expect = 8e-78, Method: Compositional matrix adjust. Identities = 178/297 (59%), Positives = 209/297 (70%), Gaps = 11/297 (3%) Query: 5 ESRGMWLGLIGVAVFSLTLPFTRIAVAELSPAFVAFGRAVVAGLCSLALLAWMRAP---- 60 E RG+ LG IGV +FS TLPFTR+AVAEL FVA AV+A L +LALLA A Sbjct: 17 ERRGLLLGFIGVTIFSQTLPFTRMAVAELDATFVALAHAVLASLLALALLAATGALRAAR 76 Query: 61 RPNAQQLRGLVITALGVVVGFPLFSSIAMRYVPAAHGAVVVGLLPLATALFGALRFGERP 120 RP Q L +TA GVVVGFPLFSS+AMR VPAAHGA++ GLLPLATALF A ERP Sbjct: 77 RPRGGQWGRLAVTAAGVVVGFPLFSSLAMRDVPAAHGAIITGLLPLATALFAAWFGRERP 136 Query: 121 SAGFWLSALAGSAIVIAFALRAGGGSFHAADFALFAAVITAAMGYAEGGRLAQSMGGQNV 180 S FW ALAGS +V++FAL G G+ H AD+ LFAA++ A+GYA GG+L++ +GG Sbjct: 137 SPWFWACALAGSVLVVSFALLRGAGTLHRADWLLFAAMVAGALGYAVGGKLSRELGGTQT 196 Query: 181 IAWALVVALPVMLPVSLWLGWQDGL-------SASAPAWLAFGYVSLFSMFIGFFFWYKG 233 IAWALVV+LP +LPV L W G AS AWL YVS FSMF+GF FWY G Sbjct: 197 IAWALVVSLPALLPVVGALAWLPGTHQAAALAQASGHAWLGLAYVSAFSMFVGFLFWYSG 256 Query: 234 LALGGIARVGQVQLLQPFMSLLGAAVIAGEALDASNMLFALAVIVVVAIGRRMAVRR 290 LA GG+ARVGQ+QLLQPFM+L+G ++ GE LDA MLFALAVI VV +GRR AVRR Sbjct: 257 LAAGGVARVGQIQLLQPFMTLIGGWLLLGEPLDAPTMLFALAVIAVVGLGRRTAVRR 313 >SMb20040 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 286 Score = 239 bits (611), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 135/285 (47%), Positives = 184/285 (64%), Gaps = 1/285 (0%) Query: 4 NESRGMWL-GLIGVAVFSLTLPFTRIAVAELSPAFVAFGRAVVAGLCSLALLAWMRAPRP 62 N++ W+ GLIGV +FS +LP TR+AV + P F+ RA +AG+ + LL R RP Sbjct: 2 NKATSGWMSGLIGVVIFSGSLPATRVAVMDFDPIFLTVARATIAGILAFCLLFAFRERRP 61 Query: 63 NAQQLRGLVITALGVVVGFPLFSSIAMRYVPAAHGAVVVGLLPLATALFGALRFGERPSA 122 L L + +LGVVVGFPL +++A+R+V +AH V +GLLPLATA+FG LR GERP Sbjct: 62 ARGDLASLAVISLGVVVGFPLMTALALRHVTSAHSIVFIGLLPLATAIFGVLRGGERPRP 121 Query: 123 GFWLSALAGSAIVIAFALRAGGGSFHAADFALFAAVITAAMGYAEGGRLAQSMGGQNVIA 182 FW+ + GSAIV+ FA R G + D + AA++ +GYAEG +L++ +GG VI Sbjct: 122 TFWVFSGLGSAIVVGFAARQGFSASPIGDLLMLAAIVACGLGYAEGAKLSRRLGGWQVIC 181 Query: 183 WALVVALPVMLPVSLWLGWQDGLSASAPAWLAFGYVSLFSMFIGFFFWYKGLALGGIARV 242 WALV++LPVM + L SA +WL FGYVS+FSM IGF FWY+GLALGGI V Sbjct: 182 WALVLSLPVMTALMLATMPSSLAGPSAASWLGFGYVSVFSMLIGFIFWYRGLALGGIVAV 241 Query: 243 GQVQLLQPFMSLLGAAVIAGEALDASNMLFALAVIVVVAIGRRMA 287 GQ+QLLQPF L A+ + GE + S + +A++ VA ++ A Sbjct: 242 GQLQLLQPFFGLALASTLLGENVSWSMLAATVAIVACVAGAKKFA 286 >AGc394 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 291 Score = 222 bits (566), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 137/292 (46%), Positives = 183/292 (62%), Gaps = 11/292 (3%) Query: 4 NESRGMWL-GLIGVAVFSLTLPFTRIAVAELSPAFVAFGRAVVAGLCSLALLAWMRAPRP 62 +++ WL GL GV +FS +LP TR+AV P F+ RA +AGL +LALL R RP Sbjct: 2 DKTTSGWLNGLTGVVIFSGSLPATRLAVTGFDPVFLTAARASIAGLLALALLFLFRQKRP 61 Query: 63 NAQQLRGLVITALGVVVGFPLFSSIAMRYVPAAHGAVVVGLLPLATALFGALRFGERPSA 122 L L+I ++GVVVGFPL +++A+R+V +AH + VGLLPLATA+F +R GERP Sbjct: 62 ARGDLTSLIIVSIGVVVGFPLLTALALRHVTSAHSIIFVGLLPLATAIFAVMRGGERPRP 121 Query: 123 GFWLSALAGSAIVIAFALRAGGGSFHA-------ADFALFAAVITAAMGYAEGGRLAQSM 175 FWL + GSA+V F+L SF A D + A+I +GYAEG L++ + Sbjct: 122 VFWLFSCLGSALVAGFSLS---NSFAARIEASLAGDLLMLGAIIVCGLGYAEGAALSRKL 178 Query: 176 GGQNVIAWALVVALPVMLPVSLWLGWQDGLSASAPAWLAFGYVSLFSMFIGFFFWYKGLA 235 GG VI+WALV++LPVMLP++ + G + AW YVSLFSM IGF FWY+GLA Sbjct: 179 GGWQVISWALVLSLPVMLPLAFFTGPETLGGIDPQAWGGLAYVSLFSMLIGFIFWYRGLA 238 Query: 236 LGGIARVGQVQLLQPFMSLLGAAVIAGEALDASNMLFALAVIVVVAIGRRMA 287 LGGIA VGQ+QLLQPF L AA + E + + + L V++ VA R+ A Sbjct: 239 LGGIAAVGQLQLLQPFFGLALAATLLHEEVSPAMIGVTLVVVLCVAGARKFA 290 >BS_ydeK [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bsu Bacillus subtilis Length = 287 Score = 218 bits (555), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 135/285 (47%), Positives = 188/285 (65%), Gaps = 1/285 (0%) Query: 4 NESRGMWL-GLIGVAVFSLTLPFTRIAVAELSPAFVAFGRAVVAGLCSLALLAWMRAPRP 62 N++ W+ G IGV +FS +LP TR+AV++ P F+ RA +AG+ + LL R P Sbjct: 2 NKTTNGWINGFIGVLIFSGSLPATRLAVSDFDPLFLTVCRAAIAGVLAGGLLLIFRQQHP 61 Query: 63 NAQQLRGLVITALGVVVGFPLFSSIAMRYVPAAHGAVVVGLLPLATALFGALRFGERPSA 122 + L L++ A GVV+GFPL +++A+++V +AH V +GLLPLATA+FG LR GERP Sbjct: 62 AKRDLISLLVVAFGVVIGFPLLTALALQHVTSAHAIVFIGLLPLATAVFGVLRGGERPRP 121 Query: 123 GFWLSALAGSAIVIAFALRAGGGSFHAADFALFAAVITAAMGYAEGGRLAQSMGGQNVIA 182 FW+ + AGS +V FAL GGGS D + A+++ +GYAEG +L++ +G VI+ Sbjct: 122 VFWIFSAAGSLLVAGFALIQGGGSSPLGDAYMLASIVVCGLGYAEGAKLSRRLGNWQVIS 181 Query: 183 WALVVALPVMLPVSLWLGWQDGLSASAPAWLAFGYVSLFSMFIGFFFWYKGLALGGIARV 242 WALV++LP+MLP+S + + PA L+ YVSLFSM IGF FWY+GLA GGIA V Sbjct: 182 WALVLSLPLMLPLSFFFTPDSWSAIGVPALLSLAYVSLFSMLIGFVFWYRGLAQGGIAAV 241 Query: 243 GQVQLLQPFMSLLGAAVIAGEALDASNMLFALAVIVVVAIGRRMA 287 GQ+QLLQPF LL A+VI E + + + +AVI+ VA RR A Sbjct: 242 GQLQLLQPFFGLLLASVILHEKVGWALVAVNIAVIMCVAAARRFA 286 >mll1137 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 291 Score = 217 bits (553), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 133/285 (46%), Positives = 179/285 (62%), Gaps = 1/285 (0%) Query: 4 NESRGMWL-GLIGVAVFSLTLPFTRIAVAELSPAFVAFGRAVVAGLCSLALLAWMRAPRP 62 +++ W+ G IGV +FS +LP TR+AV + P FV RA +AGL LA+L R RP Sbjct: 6 DKTASGWVNGFIGVLIFSGSLPATRVAVMDFDPTFVTSARAAIAGLLGLAMLLLFREKRP 65 Query: 63 NAQQLRGLVITALGVVVGFPLFSSIAMRYVPAAHGAVVVGLLPLATALFGALRFGERPSA 122 + L LVI ALGVVVGFPL +++A++++ +AH + +GLLPLATA+FG LR G+RP Sbjct: 66 DRGDLVSLVIVALGVVVGFPLLTALALKHITSAHSIIFIGLLPLATAIFGVLRGGDRPRP 125 Query: 123 GFWLSALAGSAIVIAFALRAGGGSFHAADFALFAAVITAAMGYAEGGRLAQSMGGQNVIA 182 WL + GSA+V FAL G + D + AAVI +GYAEG L++ +GG VI Sbjct: 126 ALWLFSCIGSALVAGFALTQGVTASPVGDGLMLAAVIVCGLGYAEGAALSRRLGGWQVIC 185 Query: 183 WALVVALPVMLPVSLWLGWQDGLSASAPAWLAFGYVSLFSMFIGFFFWYKGLALGGIARV 242 WAL ++LPVML +S + + AW+ GYVSLFSM IGF FWY+GLA GGIA V Sbjct: 186 WALTLSLPVMLVLSFATLPPSFAAVGSHAWIGLGYVSLFSMLIGFVFWYRGLAQGGIAAV 245 Query: 243 GQVQLLQPFMSLLGAAVIAGEALDASNMLFALAVIVVVAIGRRMA 287 GQ+QLLQPF L AA + E + ++ L V+ V ++ A Sbjct: 246 GQLQLLQPFFGLALAASLLHEQVSPLMVVVTLGVVACVFGAKKFA 290 >BMEI0170 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bme Brucella melitensis Length = 301 Score = 206 bits (523), Expect = 8e-53, Method: Compositional matrix adjust. Identities = 126/260 (48%), Positives = 167/260 (64%) Query: 4 NESRGMWLGLIGVAVFSLTLPFTRIAVAELSPAFVAFGRAVVAGLCSLALLAWMRAPRPN 63 N++ G G +GV +FS +LP TR+AV ++ P F+ RA +AGL + L R P P Sbjct: 18 NKTAGWINGFLGVLIFSGSLPATRLAVIDIDPTFLTMARASIAGLLGMVFLLLFREPFPR 77 Query: 64 AQQLRGLVITALGVVVGFPLFSSIAMRYVPAAHGAVVVGLLPLATALFGALRFGERPSAG 123 LV+ ALGVVVGFPL + +A++++ +A V +GLLPL+TA+F LR GERP Sbjct: 78 KSDAVSLVVVALGVVVGFPLLTGLALQHMTSARAIVFIGLLPLSTAIFAVLRGGERPRPL 137 Query: 124 FWLSALAGSAIVIAFALRAGGGSFHAADFALFAAVITAAMGYAEGGRLAQSMGGQNVIAW 183 FWL ++ GS +V ++A G S D + AA+I +GYAEG RL++ +GG VI W Sbjct: 138 FWLFSVVGSLVVASYAYGQGSQSTLMGDGLMLAAIIVCGLGYAEGARLSRRLGGWQVICW 197 Query: 184 ALVVALPVMLPVSLWLGWQDGLSASAPAWLAFGYVSLFSMFIGFFFWYKGLALGGIARVG 243 ALV ALPVMLP+S++ + A AW YVSLFSM IGF FWY+GLA GG A VG Sbjct: 198 ALVFALPVMLPLSVFTRPETWNGIGAMAWGGLAYVSLFSMLIGFVFWYRGLAQGGTATVG 257 Query: 244 QVQLLQPFMSLLGAAVIAGE 263 Q+QLLQPF L+ AA +AGE Sbjct: 258 QLQLLQPFFGLMLAAGVAGE 277