BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0116.p (222 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0908 [F] COG0283 Cytidylate kinase Rso Ralstonia solanacearum 258 5e-69 PA3163 [F] COG0283 Cytidylate kinase Pae Pseudomonas aeruginosa 208 7e-54 VC1916 [F] COG0283 Cytidylate kinase Vch Vibrio cholerae 206 3e-53 HI1219 [F] COG0283 Cytidylate kinase Hin Haemophilus influenzae 204 1e-52 XF2439 [F] COG0283 Cytidylate kinase Xfa Xylella fastidiosa 9a5c 201 1e-51 YPO1391 [F] COG0283 Cytidylate kinase Ype Yersinia pestis 200 2e-51 cmk [F] COG0283 Cytidylate kinase Eco Escherichia coli K12 198 6e-51 Zcmk [F] COG0283 Cytidylate kinase EcZ Escherichia coli O157:H7 ... 198 6e-51 ECs0993 [F] COG0283 Cytidylate kinase Ecs Escherichia coli O157:H7 198 6e-51 STM0980 [F] COG0283 Cytidylate kinase Sty Salmonella typhimurium... 198 9e-51 >RSc0908 [F] COG0283 Cytidylate kinase Rso Ralstonia solanacearum Length = 230 Score = 258 bits (660), Expect = 5e-69, Method: Compositional matrix adjust. Identities = 133/211 (63%), Positives = 154/211 (72%) Query: 7 PVITIDGPTASGKGTVAQKVAQQLGFHYLDSGALYRLTALSVLRRGIALNDEHALAKAAE 66 PVI IDGPTASGKGTVA ++A LGFHYLDSG+LYRL A +R I +D ++L + A Sbjct: 11 PVIAIDGPTASGKGTVAHQIADLLGFHYLDSGSLYRLVAFVSIRENIDDHDVNSLVRIAS 70 Query: 67 HLHCHFDGAHIFLSNEDVTQAIRAEEVGNTASKIAALITVRQALYGLQLSFRKPPGLVAD 126 L F HI+L EDV+ A+R E VGN AS IA VR+AL Q +F + PGLVAD Sbjct: 71 ELDVRFKADHIWLKGEDVSLALRHESVGNQASAIAVHGPVREALRARQRAFLEAPGLVAD 130 Query: 127 GRDMGTVIFPGARLKVFLTASVEARATRRYKQLIDKGFSANIEDLSRDLKERDERDMSRS 186 GRDMGTVIFP A LKVFLTASV+ARA RRYKQLI KGFSA +E LSRDL+ RD RD +RS Sbjct: 131 GRDMGTVIFPEAVLKVFLTASVQARAERRYKQLIAKGFSATVESLSRDLEARDLRDRTRS 190 Query: 187 SAPLKPAEGAYHLDTSDMTADEAVQQVLSWY 217 APL+PAE A LD+SDM+ DE V QVL WY Sbjct: 191 VAPLRPAEAARLLDSSDMSVDEVVAQVLDWY 221 >PA3163 [F] COG0283 Cytidylate kinase Pae Pseudomonas aeruginosa Length = 229 Score = 208 bits (530), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 110/215 (51%), Positives = 147/215 (68%), Gaps = 6/215 (2%) Query: 6 IPVITIDGPTASGKGTVAQKVAQQLGFHYLDSGALYRLTALSVLRRGIALNDEHALAKAA 65 +P++ IDGP+ +GKGTVA +A++LG++ LDSGALYRL A + + G+ L +E AL A Sbjct: 5 VPMLAIDGPSGAGKGTVAGLLARRLGWNLLDSGALYRLLAFAAVNHGVDLTNEEALKVLA 64 Query: 66 EHLHCHF---DGAH---IFLSNEDVTQAIRAEEVGNTASKIAALITVRQALYGLQLSFRK 119 HL F DG+H I L E+VT IR E+VG AS++AAL VR AL Q +FR+ Sbjct: 65 AHLDVQFVAADGSHGQRIILEGEEVTDVIRTEQVGAGASQVAALPAVRDALLQRQRAFRE 124 Query: 120 PPGLVADGRDMGTVIFPGARLKVFLTASVEARATRRYKQLIDKGFSANIEDLSRDLKERD 179 PGLVADGRDMGTV+FP A LK+FLTAS E RA RRY QL KG + L +++ERD Sbjct: 125 APGLVADGRDMGTVVFPDAPLKIFLTASAEERARRRYLQLKAKGADVDQSALLEEIRERD 184 Query: 180 ERDMSRSSAPLKPAEGAYHLDTSDMTADEAVQQVL 214 ERD R+ APLKPA+ A LD+++M+ + V+ ++ Sbjct: 185 ERDSQRAVAPLKPADDAILLDSTEMSIEAVVETII 219 >VC1916 [F] COG0283 Cytidylate kinase Vch Vibrio cholerae Length = 229 Score = 206 bits (524), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 106/214 (49%), Positives = 141/214 (65%), Gaps = 4/214 (1%) Query: 7 PVITIDGPTASGKGTVAQKVAQQLGFHYLDSGALYRLTALSVLRRGIALNDEHALAKAAE 66 PV+T+DGP+ +GKGT+ +A++LGF LDSGA+YR+ AL+ L G+ L E AL A Sbjct: 10 PVVTVDGPSGAGKGTLCMLLAKKLGFQLLDSGAIYRVLALAALHHGVDLESEDALVPLAT 69 Query: 67 HLHCHF----DGAHIFLSNEDVTQAIRAEEVGNTASKIAALITVRQALYGLQLSFRKPPG 122 HL F D + L EDV++ +R EE G ASK+AAL VR+AL Q +F G Sbjct: 70 HLDVQFIAEGDLVKVILEGEDVSRELRKEETGMAASKVAALPRVREALLRRQRAFASGIG 129 Query: 123 LVADGRDMGTVIFPGARLKVFLTASVEARATRRYKQLIDKGFSANIEDLSRDLKERDERD 182 LVADGRDMGTV+FP A K+FL AS E RA RR+KQL KG + L +++ERD+RD Sbjct: 130 LVADGRDMGTVVFPAAEAKIFLDASAEERARRRFKQLQLKGLDVKFDALLSEIQERDDRD 189 Query: 183 MSRSSAPLKPAEGAYHLDTSDMTADEAVQQVLSW 216 +R+ APL+PAE A LD++ +T DE V+Q L + Sbjct: 190 RNRAVAPLRPAEDALVLDSTTLTIDEVVEQALQY 223 >HI1219 [F] COG0283 Cytidylate kinase Hin Haemophilus influenzae Length = 231 Score = 204 bits (519), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 105/218 (48%), Positives = 146/218 (66%), Gaps = 4/218 (1%) Query: 8 VITIDGPTASGKGTVAQKVAQQLGFHYLDSGALYRLTALSVLRRGIALNDEHALAKAAEH 67 +IT+DGP+ +GKGT+ +A++LG+ LDSGA+YR+TAL+ L+R L +E LA+ A H Sbjct: 2 IITVDGPSGAGKGTLCYALAEKLGYALLDSGAIYRVTALAALQRKTDLTNETDLAELARH 61 Query: 68 LHCHF---DG-AHIFLSNEDVTQAIRAEEVGNTASKIAALITVRQALYGLQLSFRKPPGL 123 L F +G I L+ DV++ IR +EV + ASK+A VR AL LQ F K GL Sbjct: 62 LDIQFIPQNGEVSILLAGMDVSRLIRTQEVADAASKVAVFQKVRSALLQLQQDFAKNDGL 121 Query: 124 VADGRDMGTVIFPGARLKVFLTASVEARATRRYKQLIDKGFSANIEDLSRDLKERDERDM 183 +ADGRDMGTV+FP A++K+FL AS E RA RRYKQL +KG + N + ++KERD RD Sbjct: 122 IADGRDMGTVVFPNAQVKLFLDASAEERAKRRYKQLQNKGINGNFAQILAEIKERDFRDR 181 Query: 184 SRSSAPLKPAEGAYHLDTSDMTADEAVQQVLSWYAALG 221 +R APLKPA+ A LD++ ++ DE + Q L++ G Sbjct: 182 NREVAPLKPADDALLLDSTTLSIDEVIDQALAYIQRXG 219 >XF2439 [F] COG0283 Cytidylate kinase Xfa Xylella fastidiosa 9a5c Length = 223 Score = 201 bits (510), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 111/215 (51%), Positives = 138/215 (64%), Gaps = 5/215 (2%) Query: 6 IPVITIDGPTASGKGTVAQKVAQQLGFHYLDSGALYRLTALSVLRRGIALNDEHALAKAA 65 +PV+TIDGP+ GKGTV++ VA +LG+HYLDSGALYR A++ + ++D AL K A Sbjct: 5 VPVLTIDGPSGVGKGTVSKIVAARLGWHYLDSGALYRAVAVAADWTAVDVSDTTALVKCA 64 Query: 66 EHLHCHF----DGAHIFLSNE-DVTQAIRAEEVGNTASKIAALITVRQALYGLQLSFRKP 120 +F DG L N D T +R E G AS IAA+ VR AL Q FR+ Sbjct: 65 FDTCVNFAKCADGEMRVLVNAIDATDVLRMETTGVLASTIAAISEVRAALKERQQMFRRT 124 Query: 121 PGLVADGRDMGTVIFPGARLKVFLTASVEARATRRYKQLIDKGFSANIEDLSRDLKERDE 180 PGLVADGRDMGTVIFP A+ KVFLTA E RA RRYKQL+ KG S + L +++ RD Sbjct: 125 PGLVADGRDMGTVIFPDAQYKVFLTAKAEERAQRRYKQLMKKGVSVMLGALLEEIRARDA 184 Query: 181 RDMSRSSAPLKPAEGAYHLDTSDMTADEAVQQVLS 215 RD RS APLKPA+ A +D++ M DE V QVL+ Sbjct: 185 RDACRSVAPLKPADDALLIDSTCMEVDEVVAQVLA 219 >YPO1391 [F] COG0283 Cytidylate kinase Ype Yersinia pestis Length = 230 Score = 200 bits (508), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 100/214 (46%), Positives = 143/214 (66%), Gaps = 4/214 (1%) Query: 7 PVITIDGPTASGKGTVAQKVAQQLGFHYLDSGALYRLTALSVLRRGIALNDEHALAKAAE 66 PVIT+DGP+ +GKGT+ + +A+ L + LDSGA+YR+ AL+ L + ++ E AL A Sbjct: 6 PVITVDGPSGAGKGTLCKALAESLNWRLLDSGAIYRVLALAALHHQVDISTEEALVPLAA 65 Query: 67 HLHCHFDGAH----IFLSNEDVTQAIRAEEVGNTASKIAALITVRQALYGLQLSFRKPPG 122 HL F + + L EDV+ IR E VGNTAS+ AA VR+AL Q +FR+ PG Sbjct: 66 HLDVRFVSQNGQLQVILEGEDVSNEIRTETVGNTASQAAAFPRVREALLRRQRAFREAPG 125 Query: 123 LVADGRDMGTVIFPGARLKVFLTASVEARATRRYKQLIDKGFSANIEDLSRDLKERDERD 182 L+ADGRDMGT++FP A +K+FL AS + RA RR QL ++GF+ N E L +++ERD RD Sbjct: 126 LIADGRDMGTIVFPDAPVKIFLDASSQERAHRRMLQLQERGFNVNFERLLAEIQERDNRD 185 Query: 183 MSRSSAPLKPAEGAYHLDTSDMTADEAVQQVLSW 216 +RS APL PA A LD++ M+ ++ ++Q L++ Sbjct: 186 RNRSVAPLVPAADALVLDSTSMSIEQVIEQALAY 219 >cmk [F] COG0283 Cytidylate kinase Eco Escherichia coli K12 Length = 227 Score = 198 bits (504), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 102/214 (47%), Positives = 143/214 (66%), Gaps = 4/214 (1%) Query: 7 PVITIDGPTASGKGTVAQKVAQQLGFHYLDSGALYRLTALSVLRRGIALNDEHALAKAAE 66 PVITIDGP+ +GKGT+ + +A+ L +H LDSGA+YR+ AL+ L + + E AL A Sbjct: 6 PVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDVASEDALVPLAS 65 Query: 67 HLHCHFDGAH----IFLSNEDVTQAIRAEEVGNTASKIAALITVRQALYGLQLSFRKPPG 122 HL F + + L EDV+ IR +EV N AS++AA VR+AL Q +FR+ PG Sbjct: 66 HLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFRELPG 125 Query: 123 LVADGRDMGTVIFPGARLKVFLTASVEARATRRYKQLIDKGFSANIEDLSRDLKERDERD 182 L+ADGRDMGTV+FP A +K+FL AS E RA RR QL +KGFS N E L ++KERD+RD Sbjct: 126 LIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQEKGFSVNFERLLAEIKERDDRD 185 Query: 183 MSRSSAPLKPAEGAYHLDTSDMTADEAVQQVLSW 216 +R+ APL PA A LD++ ++ ++ +++ L + Sbjct: 186 RNRAVAPLVPAADALVLDSTTLSIEQVIEKALQY 219 >Zcmk [F] COG0283 Cytidylate kinase EcZ Escherichia coli O157:H7 EDL933 Length = 227 Score = 198 bits (504), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 102/214 (47%), Positives = 143/214 (66%), Gaps = 4/214 (1%) Query: 7 PVITIDGPTASGKGTVAQKVAQQLGFHYLDSGALYRLTALSVLRRGIALNDEHALAKAAE 66 PVITIDGP+ +GKGT+ + +A+ L +H LDSGA+YR+ AL+ L + + E AL A Sbjct: 6 PVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDVASEDALVPLAS 65 Query: 67 HLHCHFDGAH----IFLSNEDVTQAIRAEEVGNTASKIAALITVRQALYGLQLSFRKPPG 122 HL F + + L EDV+ IR +EV N AS++AA VR+AL Q +FR+ PG Sbjct: 66 HLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFRELPG 125 Query: 123 LVADGRDMGTVIFPGARLKVFLTASVEARATRRYKQLIDKGFSANIEDLSRDLKERDERD 182 L+ADGRDMGTV+FP A +K+FL AS E RA RR QL +KGFS N E L ++KERD+RD Sbjct: 126 LIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQEKGFSVNFERLLAEIKERDDRD 185 Query: 183 MSRSSAPLKPAEGAYHLDTSDMTADEAVQQVLSW 216 +R+ APL PA A LD++ ++ ++ +++ L + Sbjct: 186 RNRAVAPLVPAADALVLDSTTLSIEQVIEKALQY 219 >ECs0993 [F] COG0283 Cytidylate kinase Ecs Escherichia coli O157:H7 Length = 227 Score = 198 bits (504), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 102/214 (47%), Positives = 143/214 (66%), Gaps = 4/214 (1%) Query: 7 PVITIDGPTASGKGTVAQKVAQQLGFHYLDSGALYRLTALSVLRRGIALNDEHALAKAAE 66 PVITIDGP+ +GKGT+ + +A+ L +H LDSGA+YR+ AL+ L + + E AL A Sbjct: 6 PVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDVASEDALVPLAS 65 Query: 67 HLHCHFDGAH----IFLSNEDVTQAIRAEEVGNTASKIAALITVRQALYGLQLSFRKPPG 122 HL F + + L EDV+ IR +EV N AS++AA VR+AL Q +FR+ PG Sbjct: 66 HLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFRELPG 125 Query: 123 LVADGRDMGTVIFPGARLKVFLTASVEARATRRYKQLIDKGFSANIEDLSRDLKERDERD 182 L+ADGRDMGTV+FP A +K+FL AS E RA RR QL +KGFS N E L ++KERD+RD Sbjct: 126 LIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQEKGFSVNFERLLAEIKERDDRD 185 Query: 183 MSRSSAPLKPAEGAYHLDTSDMTADEAVQQVLSW 216 +R+ APL PA A LD++ ++ ++ +++ L + Sbjct: 186 RNRAVAPLVPAADALVLDSTTLSIEQVIEKALQY 219 >STM0980 [F] COG0283 Cytidylate kinase Sty Salmonella typhimurium LT2 Length = 227 Score = 198 bits (503), Expect = 9e-51, Method: Compositional matrix adjust. Identities = 104/214 (48%), Positives = 142/214 (66%), Gaps = 4/214 (1%) Query: 7 PVITIDGPTASGKGTVAQKVAQQLGFHYLDSGALYRLTALSVLRRGIALNDEHALAKAAE 66 PVITIDGP+ +GKGT+ + +A+ L +H LDSGA+YR+ AL+ L + L E AL A Sbjct: 6 PVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDLASEDALVPLAS 65 Query: 67 HLHCHF---DGA-HIFLSNEDVTQAIRAEEVGNTASKIAALITVRQALYGLQLSFRKPPG 122 HL F DG + L EDV+ IR +EV N AS++AA VR+AL Q +FR+ PG Sbjct: 66 HLDVRFVSTDGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFREAPG 125 Query: 123 LVADGRDMGTVIFPGARLKVFLTASVEARATRRYKQLIDKGFSANIEDLSRDLKERDERD 182 L+ADGRDMGTV+FP A +K+FL AS E RA RR QL + GFS N E L ++KERD+RD Sbjct: 126 LIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQENGFSVNFERLLAEIKERDDRD 185 Query: 183 MSRSSAPLKPAEGAYHLDTSDMTADEAVQQVLSW 216 R+ APL PA A LD++ ++ ++ +++ L + Sbjct: 186 RHRAVAPLVPAADALVLDSTRLSIEQVIEKALQY 219