BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0065.p (1504 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4112_3 [T] COG0642 Signal transduction histidine kinase Pae Ps... 253 3e-66 mlr3786_1 [T] COG0642 Signal transduction histidine kinase Mlo M... 229 3e-59 mll3725_2 [T] COG0642 Signal transduction histidine kinase Mlo M... 223 2e-57 VC1349_3 [T] COG0642 Signal transduction histidine kinase Vch Vi... 219 3e-56 VC2453_1 [T] COG0642 Signal transduction histidine kinase Vch Vi... 216 4e-55 MA2013_2 [T] COG0642 Signal transduction histidine kinase Mac Me... 214 1e-54 PA3462_2 [T] COG0642 Signal transduction histidine kinase Pae Ps... 211 7e-54 slr2098_3 [T] COG0642 Signal transduction histidine kinase Syn S... 209 5e-53 ECs3646_1 [T] COG0642 Signal transduction histidine kinase Ecs E... 209 5e-53 slr2104_3 [T] COG0642 Signal transduction histidine kinase Syn S... 207 1e-52 >PA4112_3 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 242 Score = 253 bits (645), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 141/254 (55%), Positives = 174/254 (68%), Gaps = 15/254 (5%) Query: 880 FLASVSHEIRTPMNGVLGMIQLLQRTQPLPAQQDYLDKAEISAKSLLNLLNDLLDFSKMD 939 FLA++SHEIRTPMN VLGM+QL ++T Q+DYLDKA +A SLL LLND+LD+SK++ Sbjct: 1 FLANMSHEIRTPMNAVLGMLQLARQTDLNERQRDYLDKASSAATSLLGLLNDILDYSKIE 60 Query: 940 AKQLQLDPQAFELERFGHDLAAVLAGSPPQAGVRLHIALDPQLPRRLVGDAHRLQQVLVN 999 A +L L+ FELE DLA VL+G+ V + +DP+LP +VGD RLQQ+L+N Sbjct: 61 AGKLVLEMLPFELEPLMQDLAVVLSGNQGDKDVEVIFDIDPELPSAVVGDRLRLQQILIN 120 Query: 1000 LAGNALKFTHQGHIDVHFTRLDPLPGRTVALRVEVSDTGIGIAADRLDDIFDAFTQAEAS 1059 LAGNALKFT +GH+ V RL V LRV V+DTGIGI+A++ IF+ FTQAEAS Sbjct: 121 LAGNALKFTARGHVLVSLRRL-AHDAHLVRLRVLVADTGIGISAEQQQRIFEGFTQAEAS 179 Query: 1060 TTRRYGGTGLGLAISKHLVGLMGGQLQVSSEPGRGSRFWFDLQLAVDDDSVLGPAAADDA 1119 T+RR+GGTGLGL I K LV LMGG+L+V S PG GSRFWFDL L D Sbjct: 180 TSRRFGGTGLGLFICKRLVDLMGGELRVESAPGSGSRFWFDLDL--------------DV 225 Query: 1120 ARPQPLQAASHTAG 1133 A QPL+AA AG Sbjct: 226 AHDQPLRAACPGAG 239 >mlr3786_1 [T] COG0642 Signal transduction histidine kinase Mlo Mesorhizobium loti Length = 478 Score = 229 bits (585), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 118/240 (49%), Positives = 163/240 (67%), Gaps = 6/240 (2%) Query: 868 LKAEQANSAKSLFLASVSHEIRTPMNGVLGMIQLLQRTQPLPAQQDYLDKAEISAKSLLN 927 KAE A+ AKS FLA++SHEIRTPMNGVLGM +LL +T+ P Q+ + D S +LL Sbjct: 230 FKAEAADRAKSEFLANMSHEIRTPMNGVLGMAELLAKTELTPRQKTFTDVIVKSGNALLT 289 Query: 928 LLNDLLDFSKMDAKQLQLDPQAFELERFGHDLAAVLAGSPPQAGVRLHIALDPQLPRRLV 987 ++ND+LDFSK++A QL LDP F L D+A +++ + + L + +DP+LP +V Sbjct: 290 IINDILDFSKINAGQLTLDPAPFRLTEAVEDVATLVSARVAEKNLELIVRVDPRLPAHVV 349 Query: 988 GDAHRLQQVLVNLAGNALKFTHQGH--IDVHFTRLDPLPGRTVALRVEVSDTGIGIAADR 1045 GDA R +Q++ NL GNA+KFT +GH IDV ++ + V LR+ V DTGIGI A++ Sbjct: 350 GDAGRFRQIVTNLVGNAVKFTEKGHVLIDVGGETVNDV----VQLRLRVEDTGIGIPAEK 405 Query: 1046 LDDIFDAFTQAEASTTRRYGGTGLGLAISKHLVGLMGGQLQVSSEPGRGSRFWFDLQLAV 1105 L ++F+ F Q + S+TRR+ GTGLGLAI+ LV LM G++ V SE GRGS FWF + L V Sbjct: 406 LQNVFEKFAQVDGSSTRRHEGTGLGLAIAARLVDLMAGKIGVESEIGRGSVFWFAVPLPV 465 >mll3725_2 [T] COG0642 Signal transduction histidine kinase Mlo Mesorhizobium loti Length = 328 Score = 223 bits (569), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 128/296 (43%), Positives = 186/296 (62%), Gaps = 8/296 (2%) Query: 811 GDHEPVFRVVR-DDGGIRYVQAR--AYVQRDGAGRPVRVICINLDITQRIEFENNLVDAR 867 G+ + V VR DG +R+ AR A + DG+ + +I DIT+ E L +AR Sbjct: 20 GETQEVEETVRLADGSVRHQFARKGAMIASDGS---LYLIGSTTDITELKMREAELSEAR 76 Query: 868 LKAEQANSAKSLFLASVSHEIRTPMNGVLGMIQLLQRTQPLPAQQDYLDKAEISAKSLLN 927 +A A+ AKS FLA++SHEIRTPMNGVLGM +LL ++ P Q+ + D S +LL Sbjct: 77 QRAVLADRAKSEFLANMSHEIRTPMNGVLGMAELLAKSNLDPKQKTFTDIIVKSGNALLT 136 Query: 928 LLNDLLDFSKMDAKQLQLDPQAFELERFGHDLAAVLAGSPPQAGVRLHIALDPQLPRRLV 987 ++ND+LDFSK+DA Q+ LDP F L D+A +++ + + L + ++P+L V Sbjct: 137 IINDILDFSKIDAGQMVLDPAPFNLAEAIEDVATLVSTRAKEKDLELIVRVEPRLESLFV 196 Query: 988 GDAHRLQQVLVNLAGNALKFTHQGHIDVHFTRLDPLPGRTVALRVEVSDTGIGIAADRLD 1047 GD R++Q++ NL GNA+KFT +GH+ V T + +P T L + V+DTGIGI ++L Sbjct: 197 GDVGRIRQIVTNLLGNAVKFTDEGHVLVDVTG-ERVPTGT-RLTISVTDTGIGIPEEKLK 254 Query: 1048 DIFDAFTQAEASTTRRYGGTGLGLAISKHLVGLMGGQLQVSSEPGRGSRFWFDLQL 1103 +F+ F+Q + S+TRR+ GTGLGLAI+ LV LMGG + V S G+GS FWF + L Sbjct: 255 LVFEKFSQVDTSSTRRHEGTGLGLAITSRLVELMGGTIGVESAEGKGSTFWFTVTL 310 >VC1349_3 [T] COG0642 Signal transduction histidine kinase Vch Vibrio cholerae Length = 260 Score = 219 bits (559), Expect = 3e-56, Method: Composition-based stats. Identities = 120/247 (48%), Positives = 163/247 (65%), Gaps = 1/247 (0%) Query: 861 NNLVDARLKAEQANSAKSLFLASVSHEIRTPMNGVLGMIQLLQRTQPLPAQQDYLDKAEI 920 + L A+ A+ + AK FLA++SHEIRTPMN +LGM L T Q+ Y+ + Sbjct: 1 DELRKAKEAADAMSQAKGDFLANMSHEIRTPMNAILGMAHLALNTPLDTTQRKYVTRINE 60 Query: 921 SAKSLLNLLNDLLDFSKMDAKQLQLDPQAFELERFGHDLAAVLAGSPPQAGVRLHIALDP 980 SAK+LL ++ND+LDFSKM+A +L ++ F L+ ++ AV++ + G+ + +DP Sbjct: 61 SAKNLLGIINDILDFSKMEAGKLNVERIDFNLDDVLDNVTAVVSLKAQEKGIEFLMDIDP 120 Query: 981 QLPRRLVGDAHRLQQVLVNLAGNALKFTHQGHIDVHFTRLDPLPGRTVALRVEVSDTGIG 1040 +P L+GD RL QV+VNL GNA+KFT QG I V R+ L + V LR V DTGIG Sbjct: 121 HIPLGLIGDPLRLGQVMVNLCGNAVKFTSQGEI-VLSARVSQLNEQQVTLRFAVKDTGIG 179 Query: 1041 IAADRLDDIFDAFTQAEASTTRRYGGTGLGLAISKHLVGLMGGQLQVSSEPGRGSRFWFD 1100 IA D+LDD+FDAF+QA+ S TR+YGGTGLGL+ISK LV LMGGQ+ V SE G+GS F F Sbjct: 180 IAQDKLDDLFDAFSQADNSITRQYGGTGLGLSISKQLVELMGGQITVHSEEGKGSTFEFS 239 Query: 1101 LQLAVDD 1107 + + D Sbjct: 240 VVCGLQD 246 >VC2453_1 [T] COG0642 Signal transduction histidine kinase Vch Vibrio cholerae Length = 516 Score = 216 bits (550), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 110/250 (44%), Positives = 170/250 (68%), Gaps = 2/250 (0%) Query: 855 QRIEFENNLVD-ARLKAEQANSAKSLFLASVSHEIRTPMNGVLGMIQLLQRTQPLPAQQD 913 +++E +N +D A+ +A++A KS FLA++SHE+RTP+NGV+G + + +TQ +Q D Sbjct: 268 EQLEIQNVELDIAKKRAQEAARVKSEFLANMSHELRTPLNGVIGFTRQMLKTQLTNSQAD 327 Query: 914 YLDKAEISAKSLLNLLNDLLDFSKMDAKQLQLDPQAFELERFGHDLAAVLAGSPPQAGVR 973 YL E SA +LL ++ND+LDFSK++A +L L+ FE + ++ + A S + G+ Sbjct: 328 YLQTIEKSANNLLTIINDILDFSKLEAGKLALENIPFEFQEVLEEVVNLQATSAHEKGLE 387 Query: 974 LHIALDPQLPRRLVGDAHRLQQVLVNLAGNALKFTHQGHIDVHFTRLDPLPGRTVALRVE 1033 + + +DP++PR +VGD R+QQVL NL GN++KFT +G+IDV + L + L+ Sbjct: 388 ITLKIDPKIPRGVVGDPLRIQQVLTNLVGNSIKFTERGNIDVS-VEMRALRDDVIDLQFM 446 Query: 1034 VSDTGIGIAADRLDDIFDAFTQAEASTTRRYGGTGLGLAISKHLVGLMGGQLQVSSEPGR 1093 V DTGIGI+ + +F AF+QA+AS +RRYGGTGLGL I++ LV MGG++ ++S + Sbjct: 447 VRDTGIGISERQQAQLFQAFSQADASISRRYGGTGLGLVITQKLVSHMGGEISLTSRLHQ 506 Query: 1094 GSRFWFDLQL 1103 GS FWF L+L Sbjct: 507 GSTFWFTLRL 516 >MA2013_2 [T] COG0642 Signal transduction histidine kinase Mac Methanosarcina acetivorans str.C2A Length = 296 Score = 214 bits (545), Expect = 1e-54, Method: Composition-based stats. Identities = 116/260 (44%), Positives = 163/260 (62%), Gaps = 10/260 (3%) Query: 860 ENNLVDARLKAEQANSAKSLFLASVSHEIRTPMNGVLGMIQLLQRTQPLPAQQDYLDKAE 919 E L+ A+ AE AN AK FLA++SHEIRTPMN VLGM+++L T Q++YL A Sbjct: 4 EEQLLKAKEAAESANKAKGDFLANMSHEIRTPMNAVLGMLEMLLETSLTDEQREYLQLAH 63 Query: 920 ISAKSLLNLLNDLLDFSKMDAKQLQLDPQAFELERFGHDLAAVLAGSPPQAGVRLHIALD 979 SA+SLL++++D+LDFSK++ +L+L+ +FELE + +L+G G++L ++ Sbjct: 64 ASAESLLSIIDDVLDFSKIEQNKLELEQISFELESLISHIINLLSGKAGSKGLKLAFHIE 123 Query: 980 PQLPRRLVGDAHRLQQVLVNLAGNALKFTHQGHIDVHFTRLDPLPGRT----------VA 1029 LP +GD RL+QVL N+ GNA+KFT +G I + P + VA Sbjct: 124 KDLPSTFIGDPVRLKQVLFNILGNAIKFTKKGEIALSVEVYMPSERNSGLSNSDFPEEVA 183 Query: 1030 LRVEVSDTGIGIAADRLDDIFDAFTQAEASTTRRYGGTGLGLAISKHLVGLMGGQLQVSS 1089 L +V DTGIGI ++L IFD F QA+AS TR YGGTGLGLAIS LV LM G++ V S Sbjct: 184 LLFKVKDTGIGIPPEKLSQIFDPFIQADASVTREYGGTGLGLAISSQLVELMEGRIWVES 243 Query: 1090 EPGRGSRFWFDLQLAVDDDS 1109 E G+G F+F +++ + S Sbjct: 244 EVGKGCTFYFTVRVKRGESS 263 >PA3462_2 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 385 Score = 211 bits (538), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 112/229 (48%), Positives = 160/229 (69%), Gaps = 1/229 (0%) Query: 876 AKSLFLASVSHEIRTPMNGVLGMIQLLQRTQPLPAQQDYLDKAEISAKSLLNLLNDLLDF 935 AKS FLA +SHEIRTP+NGVLGM+QLL+ T Q Y++ S +L++++ND+LD+ Sbjct: 1 AKSRFLAKMSHEIRTPLNGVLGMLQLLRDTPLDRGQAAYVETIASSGSALMSVINDILDY 60 Query: 936 SKMDAKQLQLDPQAFELERFGHDLAAVLAGSPPQAGVRLHIALDPQLPRRLVGDAHRLQQ 995 +++++ +L L+ F+LE D A+ + + + LH+ LD +PRRL GD RL+Q Sbjct: 61 ARIESGKLHLERIDFDLEELLSDTLALFSAQAVEKRLHLHLGLDRGVPRRLNGDPTRLRQ 120 Query: 996 VLVNLAGNALKFTHQGHIDVHFTRLDPLPGRTVALRVEVSDTGIGIAADRLDDIFDAFTQ 1055 VL+NL NALKFT +GH+ V R GR L VSD+GIGI+A +F++F+Q Sbjct: 121 VLMNLLSNALKFTAEGHVAVRVQRRFDEGGRERLL-YSVSDSGIGISAQAQKTLFESFSQ 179 Query: 1056 AEASTTRRYGGTGLGLAISKHLVGLMGGQLQVSSEPGRGSRFWFDLQLA 1104 A++STTRRYGG+GLGLAIS+ LV +MGG+++VSSEPG+G+RF DL L+ Sbjct: 180 ADSSTTRRYGGSGLGLAISRELVQMMGGRIEVSSEPGKGTRFSVDLPLS 228 >slr2098_3 [T] COG0642 Signal transduction histidine kinase Syn Synechocystis Length = 280 Score = 209 bits (531), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 109/247 (44%), Positives = 159/247 (64%), Gaps = 1/247 (0%) Query: 852 DITQRIEFENNLVDARLKAEQANSAKSLFLASVSHEIRTPMNGVLGMIQLLQRTQPLPAQ 911 DIT E + A+ AE+A+ K+ FLA++SHEIRTPMN V+GM L +T P Q Sbjct: 22 DITPIKAAEAEMKRAKELAEEASRIKADFLANMSHEIRTPMNAVIGMTHLALKTDLTPRQ 81 Query: 912 QDYLDKAEISAKSLLNLLNDLLDFSKMDAKQLQLDPQAFELERFGHDLAAVLAGSPPQAG 971 ++YL K S + LL ++ND+LDFSK++A +L ++ F+L++ ++A +++ G Sbjct: 82 REYLHKIRFSGQHLLGVINDILDFSKIEAGKLPMESIDFDLDKVLDNVATLISEKATNKG 141 Query: 972 VRLHIALDPQLPRRLVGDAHRLQQVLVNLAGNALKFTHQGHIDVHFTRLDPLPGRTVALR 1031 + L +D LPR +GD RL Q+L+N A NA+KFT QG I + RL + V L Sbjct: 142 LELLFDIDRNLPRHFIGDPLRLGQILINYANNAVKFTEQGDITI-VVRLQEYRDQDVVLY 200 Query: 1032 VEVSDTGIGIAADRLDDIFDAFTQAEASTTRRYGGTGLGLAISKHLVGLMGGQLQVSSEP 1091 + V DTGIGI + + ++F++F QA++STTR +GGTGLGLAI K + LMGG++ V SE Sbjct: 201 LAVKDTGIGIKPEHIANLFNSFQQADSSTTRNFGGTGLGLAICKRIAELMGGEVGVESEY 260 Query: 1092 GRGSRFW 1098 G+GS FW Sbjct: 261 GQGSTFW 267 >ECs3646_1 [T] COG0642 Signal transduction histidine kinase Ecs Escherichia coli O157:H7 Length = 531 Score = 209 bits (531), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 109/263 (41%), Positives = 170/263 (64%), Gaps = 3/263 (1%) Query: 855 QRIEFENNLVD-ARLKAEQANSAKSLFLASVSHEIRTPMNGVLGMIQLLQRTQPLPAQQD 913 +++E +N +D A+ +A++A KS FLA++SHE+RTP+NGV+G +L +T+ P Q+D Sbjct: 270 EQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRD 329 Query: 914 YLDKAEISAKSLLNLLNDLLDFSKMDAKQLQLDPQAFELERFGHDLAAVLAGSPPQAGVR 973 +L+ E SA +LL ++ND+LDFSK++A +L L+ F L ++ +LA S G+ Sbjct: 330 HLNTIERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLE 389 Query: 974 LHIALDPQLPRRLVGDAHRLQQVLVNLAGNALKFTHQGHIDVHFTRLDPLPGRTVALRVE 1033 L + + +P ++GD RLQQ++ NL GNA+KFT G+ID+ + L V + V+ Sbjct: 390 LTLNIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEK-RALSNTKVQIEVQ 448 Query: 1034 VSDTGIGIAADRLDDIFDAFTQAEASTTRRYGGTGLGLAISKHLVGLMGGQLQVSSEPGR 1093 + DTGIGI +F AF QA+AS +RR+GGTGLGL I++ LV MGG + S+P R Sbjct: 449 IRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNR 508 Query: 1094 GSRFWFDLQLAVDDDSVL-GPAA 1115 GS FWF + L ++ + ++ GP+ Sbjct: 509 GSTFWFHINLDLNPNIIIEGPST 531 >slr2104_3 [T] COG0642 Signal transduction histidine kinase Syn Synechocystis Length = 270 Score = 207 bits (528), Expect = 1e-52, Method: Composition-based stats. Identities = 113/259 (43%), Positives = 164/259 (63%), Gaps = 6/259 (2%) Query: 860 ENNLVDARLKAEQANSAKSLFLASVSHEIRTPMNGVLGMIQLLQRTQPLPAQQDYLDKAE 919 + +L++A+L AE A AKS FLA++SHEIRTPMN ++GM +L+ +T Q++YL K + Sbjct: 1 QESLLEAKLVAEGATKAKSEFLANMSHEIRTPMNAIIGMSELVLQTDLTSQQRNYLQKVQ 60 Query: 920 ISAKSLLNLLNDLLDFSKMDAKQLQLDPQAFELERFGHDLAAVLAGSPPQAGVRLHIALD 979 + + LL ++N++LDFSKM+A +L+L+ + F +E +L ++L G+ L+ LD Sbjct: 61 YAGELLLGIINNILDFSKMEAGKLELEQKPFSVEEVMGNLHSILGIQAEAKGLTLNFHLD 120 Query: 980 PQLPRRLVGDAHRLQQVLVNLAGNALKFTHQGHIDVHFTRLDPLPGRTVALRVEVSDTGI 1039 P++P LVGD RL Q+L+NL NA+KFT+QG I + +L L+ V+DTGI Sbjct: 121 PRIPPILVGDRLRLSQILINLGNNAVKFTNQGEITIR-GQLLKTENEQTKLQFSVTDTGI 179 Query: 1040 GIAADRLDDIFDAFTQAEASTTRRYGGTGLGLAISKHLVGLMGGQLQVSSEPGRGSRFWF 1099 G+ D+ +F F Q E ST+R+YGGTGLGLAISK L LMGG + + S G+GS F F Sbjct: 180 GLTPDQQSKLFQWFNQGETSTSRQYGGTGLGLAISKSLTELMGGDIWLESVVGQGSTFHF 239 Query: 1100 DLQLAVDDDSVLGPAAADD 1118 + L PA A D Sbjct: 240 TVCLG-----TASPAVAQD 253