BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0015.p (403 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr7407 [GEPR] COG0477 Permeases of the major facilitator superf... 324 3e-88 Rv2994 [GEPR] COG0477 Permeases of the major facilitator superfa... 100 8e-21 MT3072 [GEPR] COG0477 Permeases of the major facilitator superfa... 98 4e-20 PA0811 [GEPR] COG0477 Permeases of the major facilitator superfa... 75 4e-13 AGl2008 [GEPR] COG0477 Permeases of the major facilitator superf... 71 5e-12 >mlr7407 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 430 Score = 324 bits (830), Expect = 3e-88, Method: Compositional matrix adjust. Identities = 230/414 (55%), Positives = 265/414 (64%), Gaps = 26/414 (6%) Query: 2 QAAAPVLPRPSPSPSPHRWKVLAAGVAANASFSAVFSGIPVTSVVLRSDYRLSNTQLGLA 61 AAAP SP HRWKVL GVAANASFSA FSGIP T+VVLR Y LSN +LGLA Sbjct: 19 SAAAPAGRVFSPG---HRWKVLGIGVAANASFSATFSGIPATAVVLRQGYHLSNAELGLA 75 Query: 62 LGLLSLGVALGELPWGVLTDRWGDRKVLLAGLLGASAA--LGLLMLYALPGQGAANFAWL 119 LG+L LGVAL ELPWG+LTDRWGDR+VLL G LGA+AA L + ML G + L Sbjct: 76 LGVLGLGVALSELPWGLLTDRWGDRRVLLIG-LGATAAWLLAMAMLVVPTRSGVPDVMLL 134 Query: 120 CAGLMLAGLLGGSVNGASGRAIMGWFGEGERGLAMSIRQTAVPLGGGLGALLLPTLAAQA 179 A L+ GLLGGSVNG+SGRAIMGWF E ERG AMSIRQTAVPLGGGLGAL+LP+LA Sbjct: 135 SASLLFTGLLGGSVNGSSGRAIMGWFRENERGFAMSIRQTAVPLGGGLGALVLPSLALAF 194 Query: 180 GFGAVFAALMAACLASVGLVLRWLREAPVALAHGAAPVVGAASMALRSKLVWRLALGIGL 239 GF AVF L A S RWL E P A A A LR+ VWR+A IGL Sbjct: 195 GFSAVFTLLAGASALSALFAWRWLHEPPAAAH--VAASAAAGPAPLRNIEVWRIATAIGL 252 Query: 240 LCAPQVALLSFGGIFLQESAQASVLAISVLLTLVQLGAAAAFIASGRWTDRRGQRRDYLR 299 LC PQVA+L+F +FL + +AIS L VQ+GA + SGR+TDR G RR +LR Sbjct: 253 LCFPQVAVLTFASVFLHDFVGLGTVAISASLAAVQIGAMVMRVWSGRFTDRHGNRRQFLR 312 Query: 300 GCALASAALFG------------------LLGVLAPLLVAAGVVVSAWHGVAYTELAVVA 341 C+ S F L+ VL +L+ AG+ VSAWHGVAYTELA +A Sbjct: 313 SCSALSGLAFSVLWLMVLAGSAVPGGQSFLIAVLPFVLIVAGISVSAWHGVAYTELATLA 372 Query: 342 GAGQVGTALGLGNSCVFLVFFLAAQAIPPLLHWQGWPAVWLATALVALLVWPLF 395 GAG VGTAL L N+ VF+ FFL AIP LLH WP VWL+ +L AL+ WP+F Sbjct: 373 GAGHVGTALSLANTFVFVGFFLVPVAIPGLLHLWSWPGVWLSASLCALIAWPIF 426 >Rv2994 [GEPR] COG0477 Permeases of the major facilitator superfamily Mtu Mycobacterium tuberculosis H37Rv Length = 445 Score = 100 bits (248), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 115/390 (29%), Positives = 167/390 (42%), Gaps = 25/390 (6%) Query: 19 RWKVLAAGVAANASFSAVFSGIPVTSVVLRSDYRLSNTQLGLALGLLSLGVALGELPWGV 78 RW ++ + AS +G+ L + + GL + S G+ + WG Sbjct: 11 RWAIMIVSLGVTASSFLFINGVAFLIPRLENARGTPLSHAGLLASMPSWGLVVTMFAWGY 70 Query: 79 LTDRWGDRKVLLAGLLGASAALGLLMLYALPGQGAANFAWLCAGLMLAGLLGGSVNGASG 138 L D G+R V+ G +AA + W+ L L G+ G N A G Sbjct: 71 LLDHVGERMVMAVGSALTAAAAYAAA-------SVHSLLWIGVFLFLGGMAAGGCNSAGG 123 Query: 139 RAIMGWFGEGERGLAMSIRQTAVPLGGGLGALLLPTLAAQAGFGAVFAALMAACLASVGL 198 R + GWF +RGLAM IRQTA PLG GAL++P LA + + + LA+V Sbjct: 124 RLVSGWFPPQQRGLAMGIRQTAQPLGIASGALVIPELAERGVHAGLMFPAVVCTLAAVAS 183 Query: 199 VLRWLREAPVALAHGAAPVVGAASMALRSKLVWRLALGIGLLCAPQVALLSFGGIFLQES 258 VL + P + A AS S ++WR+ LL PQ ++F ++L Sbjct: 184 VLGIVD--PPRKSRTKASEQELASPYRGSSILWRIHAASALLMMPQTVTVTFMLVWLINH 241 Query: 259 AQASVLAISVLLTLVQLGAAAAFIASGRWTDRRGQRRDYLRGCALASAALFGLLGVLAP- 317 SV VL+T+ QL A +A GRW+D G R +R A A+AA LL + Sbjct: 242 HGWSVAQAGVLVTISQLLGALGRVAVGRWSDHVGSRMRPVRLIAAAAAATLFLLAAVDNE 301 Query: 318 -------LLVAAGVVVSAWHGVAYTELAVVAGAGQVGTALGLGNSCVFLVFFLAAQAIPP 370 L++A V+ +G+ T + AG G ALG+ N+ L+ A A PP Sbjct: 302 GSRYDVLLMIAISVIAVLDNGLEATAITEYAGPYWSGRALGIQNTTQRLM----AAAGPP 357 Query: 371 ----LLHWQGWPAVWLATALVALLVWPLFP 396 L+ +P W + L PL P Sbjct: 358 LFGSLITTAAYPTAWALCGVFPLAAVPLVP 387 >MT3072 [GEPR] COG0477 Permeases of the major facilitator superfamily MtC Mycobacterium tuberculosis CDC1551 Length = 445 Score = 97.8 bits (242), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 114/390 (29%), Positives = 166/390 (42%), Gaps = 25/390 (6%) Query: 19 RWKVLAAGVAANASFSAVFSGIPVTSVVLRSDYRLSNTQLGLALGLLSLGVALGELPWGV 78 RW ++ + AS +G+ L + + GL + S G+ + WG Sbjct: 11 RWAIMIVSLGVTASSFLFINGVAFLIPRLENARGTPLSHAGLLASMPSWGLVVTMFAWGY 70 Query: 79 LTDRWGDRKVLLAGLLGASAALGLLMLYALPGQGAANFAWLCAGLMLAGLLGGSVNGASG 138 L D G+R V+ G +AA + W+ L L G+ G N A G Sbjct: 71 LLDHVGERMVMAVGSALTAAAAYAAA-------SVHSLLWIGVFLFLGGMAAGGCNSAGG 123 Query: 139 RAIMGWFGEGERGLAMSIRQTAVPLGGGLGALLLPTLAAQAGFGAVFAALMAACLASVGL 198 R + GWF +RGLAM IRQTA PLG GAL++P LA + + + LA+V Sbjct: 124 RLVSGWFPPQQRGLAMGIRQTAQPLGIASGALVIPELAERGVHAGLMFPAVVCTLAAVAS 183 Query: 199 VLRWLREAPVALAHGAAPVVGAASMALRSKLVWRLALGIGLLCAPQVALLSFGGIFLQES 258 VL + P + A AS S ++WR+ LL PQ ++F ++L Sbjct: 184 VLGIVD--PPRKSRTKASEQELASPYRGSSILWRIHAASALLMMPQTVTVTFMLVWLINH 241 Query: 259 AQASVLAISVLLTLVQLGAAAAFIASGRWTDRRGQRRDYLRGCALASAALFGLLGVLAP- 317 SV VL+T+ QL A +A GRW+D G R +R A A+AA LL + Sbjct: 242 HGWSVAQAGVLVTISQLLGALGRVAVGRWSDHVGSRMRPVRLIAAAAAATLFLLAAVDNE 301 Query: 318 -------LLVAAGVVVSAWHGVAYTELAVVAGAGQVGTALGLGNSCVFLVFFLAAQAIPP 370 L++A V+ +G+ + AG G ALG+ N+ L+ A A PP Sbjct: 302 GSRYDVLLMIAISVIAVLDNGLEAAAITEYAGPYWSGRALGIQNTTQRLM----AAAGPP 357 Query: 371 ----LLHWQGWPAVWLATALVALLVWPLFP 396 L+ +P W + L PL P Sbjct: 358 LFGSLITTAAYPTAWALCGVFPLAAVPLVP 387 >PA0811 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 415 Score = 74.7 bits (182), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 79/281 (28%), Positives = 127/281 (45%), Gaps = 16/281 (5%) Query: 18 HRWKVLAAGVAANASFSAVFSGIPVTSVVLRSDYRLSNTQLGLALGLLSLGVALGELPWG 77 +RW +L A A GI +V +++D +LS+ Q+GL + L +G L G Sbjct: 13 YRWVILLIATFAQACACFFVQGIGAIAVFVQNDLQLSSLQIGLLVSAAQLVPIVGLLVAG 72 Query: 78 VLTDRWGDRKVLLAGLLGASAALGLLMLYALPGQGAANFAWLCAGLMLAGLLGGSVNGAS 137 L DR+ +R V+ G L + AL A ++ + L++ G + Sbjct: 73 ELLDRYSERLVVGLGTLIVALAL-------CASLWATDYLTILLFLVVVGAGYSTAQPGG 125 Query: 138 GRAIMGWFGEGERGLAMSIRQTAVPLGGGLGALLLPTLAAQAGFGAVF-AALMAACLASV 196 +++ WF + + G AM IRQ +PLGG L A LLP LA G+ + F A + A L ++ Sbjct: 126 SKSVSRWFAKTQLGFAMGIRQAGLPLGGALSAALLPYLAGVYGWRSAFLAGGLVAFLGAL 185 Query: 197 GLVLRWLREAPVALAHGAAPVVGAASMALRSKLVWRLALGIGLLCAPQVALLS------- 249 +L + R P A A GA P ++S+L + + VAL+S Sbjct: 186 AFMLFY-RTPPDAPAPGANPAERDLGAVVKSRLAMITDPAMKNIVCSGVALISVQYGILV 244 Query: 250 FGGIFLQESAQASVLAISVLLTLVQLGAAAAFIASGRWTDR 290 F ++L E+ + + + LL + Q A I W+DR Sbjct: 245 FTVLYLHETLEIGIGMAATLLFVAQGSGVAGRILLAAWSDR 285 >AGl2008 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 418 Score = 70.9 bits (172), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 70/205 (34%), Positives = 100/205 (48%), Gaps = 20/205 (9%) Query: 9 PRPSPSPSPHRWKVLAAGVAANASFSAVFSGIPVTSVVLRSDYRLSNTQLGLALGLLSLG 68 P P+P+ PH W VLA V + S V GI + R + +S LA+ +++ G Sbjct: 10 PGPAPAADPHIWAVLAVAVGTQTAGSFVSQGIYILVPFWREAFGVSLASASLAVTVMN-G 68 Query: 69 VALGEL-PWGVLTDRWGDRKVLLAGLLGASAALGLLMLYALPGQGAANFA-WLCAGLMLA 126 V + + G D G+R+++ +LG + A+ AA FA L A L+ Sbjct: 69 VQIATMFTLGRAIDIHGERRIVGIAMLGMAIAMAC----------AATFANSLPALLVCI 118 Query: 127 GLLGGS---VNGASGRAIMGWFGEGERGLAMSIRQTAVPLGGGLGALLLPTLAAQAGFGA 183 LGG+ V RAIM WF +RG+A RQ AVP G + A LLP +A + G+ A Sbjct: 119 AFLGGTYAAVQPGGTRAIMRWFPPAKRGIATGFRQAAVPFGTMIAAALLPFMAVRYGWHA 178 Query: 184 VFAALMAACLASVGLVLRW--LREA 206 AA + A ++ VG L W REA Sbjct: 179 --AAWLCAGVSIVGAALFWGLYREA 201