BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0013.p (385 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Cj0846 [R] COG1408 Predicted phosphohydrolases Cje Campylobacter... 167 5e-41 HP1044 [R] COG1408 Predicted phosphohydrolases Hpy Helicobacter ... 165 1e-40 jhp0380 [R] COG1408 Predicted phosphohydrolases jHp Helicobacter... 165 2e-40 MTH1179 [R] COG1408 Predicted phosphohydrolases Mth Methanotherm... 134 4e-31 CAC3027 [R] COG1408 Predicted phosphohydrolases Cac Clostridium ... 122 2e-27 aq_1054 [R] COG1408 Predicted phosphohydrolases Aae Aquifex aeol... 115 2e-25 lin0757 [R] COG1408 Predicted phosphohydrolases Lin Listeria inn... 98 2e-20 all0251 [R] COG1408 Predicted phosphohydrolases Nos Nostoc sp. P... 98 4e-20 all0250 [R] COG1408 Predicted phosphohydrolases Nos Nostoc sp. P... 95 2e-19 BS_ykuE [R] COG1408 Predicted phosphohydrolases Bsu Bacillus sub... 89 2e-17 >Cj0846 [R] COG1408 Predicted phosphohydrolases Cje Campylobacter jejuni Length = 374 Score = 167 bits (422), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 95/254 (37%), Positives = 140/254 (55%), Gaps = 14/254 (5%) Query: 136 NARRTAAVVEVSVPIANLPAALEGFSIVQISDIHVGPTIKAPYLQAIVDKVNALSPDVVA 195 NA +T V V V I NL L+ IV ++DIH+G + +L ++ KVN SPD+V Sbjct: 130 NALKTPEVKSVDVEIPNLKKDLK---IVMLTDIHLGKNLHENFLDKLITKVNLQSPDMVV 186 Query: 196 ITGDLVDGSVRQLAPHTAPLAQLRARHGAYFVTGNHEYYSNAHEWIEEVRR-LGLTVLMN 254 I GDL+D + + L + + L + +G ++ GNHEYY +E ++ +R+ + +L+N Sbjct: 187 IVGDLIDTNPKDLKNYISKLNDFNSTYGTFYALGNHEYYHGINEVLDLLRKHTNMKILVN 246 Query: 255 EHVVLRHDDAGLV-LAGVTDYTAHHFDPAHRSDPHAAI-ADAPDGHPRILLAHQPRSAQA 312 +++ D G + +AG+ D D + A I D ILL HQP++A Sbjct: 247 QNL-----DLGFIDIAGLGDLAG--LDRGLYAPDLARIKVDLNTSKASILLTHQPKTALL 299 Query: 313 AAEAGFDLQLSGHTHGGQFFPWNFFVPLQQPYVAGLKRL-QGLWVYVSRGTSYWGPPKRL 371 + FDL LSGHTHGGQ FP+ F V LQQ +V GL L + +YVS G +WGP R+ Sbjct: 300 YDLSDFDLVLSGHTHGGQIFPFMFLVKLQQGFVHGLYDLGEKTKLYVSSGAGFWGPSLRV 359 Query: 372 LAPSEITRVRLTAR 385 APSEI + L + Sbjct: 360 FAPSEIVILNLKGK 373 >HP1044 [R] COG1408 Predicted phosphohydrolases Hpy Helicobacter pylori 26695 Length = 370 Score = 165 bits (418), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 98/258 (37%), Positives = 138/258 (53%), Gaps = 16/258 (6%) Query: 133 GYLNARRTAAVVEVSVPIANLPAALEGFSIVQISDIHVGPTIKAPYLQAIVDKVNALSPD 192 G+ + E + + L L+ I+ ++D+HVG ++ ++ IV++VN D Sbjct: 121 GFYEGLARPKIKETPIYLDKLDKELK---IILLTDMHVGSLLQKDFVDYIVEEVNQKEVD 177 Query: 193 VVAITGDLVDGSVRQLAPHTAPLAQLRARHGAYFVTGNHEYYSNAHEWIEEVRRLGLTVL 252 +V I GDLVD S+ ++ PL L++ HG ++V GNHEYY + + L LT+L Sbjct: 178 MVLIGGDLVDESIEKVKSFLLPLNNLKSTHGTFYVPGNHEYYHGIEPILSFLDTLNLTIL 237 Query: 253 MNEHVVLRHDDAGLVLAGVTDYTA---HHFDPAHRSDPHAAIADAPDGHPRILLAHQPRS 309 NE V L G+ L GV DY A +F P D A+ + P ILLAHQP+ Sbjct: 238 GNECVHL----GGINLCGVYDYFARKRQNFAP----DIDKALKKRNESKPTILLAHQPKQ 289 Query: 310 AQAAAEA-GFDLQLSGHTHGGQFFPWNFFVPLQQPYVAGL-KRLQGLWVYVSRGTSYWGP 367 ++ E+ DL LSGHTH GQ FP++ V L Q Y+ GL K +YVS G YWG Sbjct: 290 IRSLKESHSVDLVLSGHTHAGQIFPFSLLVKLAQTYLHGLYKHSPTTQIYVSSGAGYWGI 349 Query: 368 PKRLLAPSEITRVRLTAR 385 P R LAPSEI +RL + Sbjct: 350 PLRFLAPSEIAYLRLLPK 367 >jhp0380 [R] COG1408 Predicted phosphohydrolases jHp Helicobacter pylori J99 Length = 370 Score = 165 bits (417), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 96/255 (37%), Positives = 136/255 (53%), Gaps = 16/255 (6%) Query: 133 GYLNARRTAAVVEVSVPIANLPAALEGFSIVQISDIHVGPTIKAPYLQAIVDKVNALSPD 192 G+ + E + + L L+ I+ ++D+HVG ++ ++ IV++VN D Sbjct: 121 GFYEGLARPKIKETPIYLDKLDKELK---IILLTDMHVGSLLQKDFVNYIVEEVNQKEVD 177 Query: 193 VVAITGDLVDGSVRQLAPHTAPLAQLRARHGAYFVTGNHEYYSNAHEWIEEVRRLGLTVL 252 +V I GDLVD ++ ++ PL L++ HG ++V GNHEYY + + L +T+L Sbjct: 178 MVLIGGDLVDENIEKVKSFLLPLNNLKSTHGTFYVPGNHEYYHGIEPILSFLNTLDMTIL 237 Query: 253 MNEHVVLRHDDAGLVLAGVTDYTA---HHFDPAHRSDPHAAIADAPDGHPRILLAHQPRS 309 NE V L G+ L GV DY A F P D A+ P ILLAHQP+ Sbjct: 238 GNECVHL----GGINLCGVYDYFARKRQDFAP----DIDKALKKRDSSKPTILLAHQPKQ 289 Query: 310 AQAAAEA-GFDLQLSGHTHGGQFFPWNFFVPLQQPYVAGLKRLQG-LWVYVSRGTSYWGP 367 ++ E+ DL LSGHTH GQ FP++ V L Q Y+ GL + G +YVS G YWG Sbjct: 290 IRSLKESHSIDLVLSGHTHAGQIFPFSLLVKLAQTYLHGLYKHSGTTQIYVSSGAGYWGI 349 Query: 368 PKRLLAPSEITRVRL 382 P R LAPSEI +RL Sbjct: 350 PLRFLAPSEIAYLRL 364 >MTH1179 [R] COG1408 Predicted phosphohydrolases Mth Methanothermobacter thermautotrophicus Length = 344 Score = 134 bits (337), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 92/264 (34%), Positives = 139/264 (52%), Gaps = 21/264 (7%) Query: 121 LALALTAVATVIGYLNARRTAAV-VEVSVPIANLPAALEGFSIVQISDIHVGPTIKAPYL 179 LA++L A++ G AR+ VE+ P+ E VQ+SDIH+G A +L Sbjct: 96 LAVSLAALSVSYGVFRARKIEVKRVEIPFPVE------ESLRFVQLSDIHLGTVRSAGFL 149 Query: 180 QAIVDKVNALSPDVVAITGDLVDGSVRQLAPHTAPLAQLRARHGAYFVTGNHEYYSNAHE 239 + + + V + V ITGDL+DGS R + ++ ++ L +FV+GNH+ YS + Sbjct: 150 KEVSEAVRRVEAAAVLITGDLLDGS-RPV--DSSIISSLETGAPIFFVSGNHDTYSG--D 204 Query: 240 WIEEVRRLGLTVLMNEHVVLRHDDAGLVLAGVTDYTAHHFDPAHRSDPHAAIADAPDGHP 299 + V G+ + +++ V+ + G+ + GV H PA + + + P Sbjct: 205 FRSTVSDAGI-MCIDQSVI---EFEGIQIIGVGYSMERHSLPAILD-----LLEFDEDRP 255 Query: 300 RILLAHQPRSAQAAAEAGFDLQLSGHTHGGQFFPWNFFVPLQQPYVAGLKRLQGLWVYVS 359 +LL H P + A E G DLQLSGHTHGGQF+P+N V L P++ GL G ++YVS Sbjct: 256 VLLLHHLPVDWEDARERGVDLQLSGHTHGGQFYPFNIIVGLMFPFLRGLYSDSGGFLYVS 315 Query: 360 RGTSYWGPPKRLLAPSEITRVRLT 383 GT WGPP RL + EIT + L Sbjct: 316 EGTGTWGPPVRLGSSCEITVIDLV 339 >CAC3027 [R] COG1408 Predicted phosphohydrolases Cac Clostridium acetobutylicum Length = 392 Score = 122 bits (305), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 71/239 (29%), Positives = 120/239 (50%), Gaps = 11/239 (4%) Query: 147 SVPIANLPAALEGFSIVQISDIHVGPTIKAPYLQAIVDKVNALSPDVVAITGDLVDGSV- 205 ++ I L+ ++V +SD+H+G I+ + +V +N L PDVV GD+VD S Sbjct: 158 NISINKKAGKLKQLNVVMVSDVHMGIMIRERGIDKLVTSINKLKPDVVFFCGDMVDESTP 217 Query: 206 RQLAPH-TAPLAQLRARHGAYFVTGNHEYYS-NAHEWIEEVRRLGLTVLMNEHVVLRHDD 263 L + ++ ++ +++G Y +TGNHEY + N+ + +++ + VL ++ V + D Sbjct: 218 TSLEKYYSSAFKEIISKYGVYAITGNHEYATQNSEVAMNYMKKADIKVLEDKAVKV---D 274 Query: 264 AGLVLAGVTDYTAHHFDPAHRSDPHAAIADAPDGHPRILLAHQPRSAQAAAEAGFDLQLS 323 + G D P + + +A P I L H+P + + A + G DLQLS Sbjct: 275 NSFYVIGRNDAAGGKVKPLNE-----IMKNADKRLPIIALNHRPVALEEAEKNGVDLQLS 329 Query: 324 GHTHGGQFFPWNFFVPLQQPYVAGLKRLQGLWVYVSRGTSYWGPPKRLLAPSEITRVRL 382 GHTH GQ FP+NF L G + + + V+ G WGPP R+ EI +++ Sbjct: 330 GHTHEGQIFPFNFTTKLVFEDDYGYLKKKDFNLIVTSGYGTWGPPIRIGTKGEIVNIKI 388 >aq_1054 [R] COG1408 Predicted phosphohydrolases Aae Aquifex aeolicus Length = 261 Score = 115 bits (287), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 78/245 (31%), Positives = 121/245 (49%), Gaps = 7/245 (2%) Query: 143 VVEVSVPIANLPAALEGFSIVQISDIHVGPTIKAPYLQAIVDKVNALSPDVVAITGDLVD 202 V + ++ LP E I+ SD+H+GP ++ ++ + PD++ TGD VD Sbjct: 20 VEKYTIETEKLPKGTE-IKIMNASDMHLGPVMREDRVEMVKRVYEREKPDILVATGDTVD 78 Query: 203 GSVRQLAPHTAPLAQLRARHGAYFVTGNHEYYSNAHEWIEEVRRLGLTVLMNEHVVLRHD 262 G+++ L LA+L G + V GNHEYY ++ ++ +R+ G VL E V + + Sbjct: 79 GNMKNLDYLAQMLAELNPPLGKFAVLGNHEYYVGLNQSLDFLRKAGFRVLRGEAVEINN- 137 Query: 263 DAGLVLAGVTDYTAHHFDPAHRSDPHAAIADAPDGHPRILLAHQPRSAQAAAEAGFDLQL 322 LV+AGV D +D + + ILL H+PR + A + DL L Sbjct: 138 --FLVIAGVDDSDGKRLGYRVFTDELEVLKNVDTKKYVILLKHKPRIKREAIKY-VDLVL 194 Query: 323 SGHTHGGQ-FFPWNFFVPLQQPYVAGLKRLQ-GLWVYVSRGTSYWGPPKRLLAPSEITRV 380 SGHTHGG FF + L G+K L G ++ VS+G GPP RLL+P ++ V Sbjct: 195 SGHTHGGVLFFVGYTILRLIFETDRGIKELAPGKYIIVSKGVGTGGPPMRLLSPPDVVIV 254 Query: 381 RLTAR 385 + + Sbjct: 255 TIKGK 259 >lin0757 [R] COG1408 Predicted phosphohydrolases Lin Listeria innocua Length = 293 Score = 98.2 bits (243), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 88/291 (30%), Positives = 127/291 (43%), Gaps = 24/291 (8%) Query: 115 IELTAWLALALTAVATVIGYLNARRTAAVVEVSVPIANLPAALEGFSIVQISDIHVGPTI 174 ++ T W L A T Y + + V + + +PA +G + VQ+SD+H Sbjct: 1 MKKTGWGILGAVAAFTGYAYWSTKHLT-VTDYEILSDKIPAEWDGATFVQLSDLHSASF- 58 Query: 175 KAPYLQAIVDKVNALSPDVVAITGDLVDGSVRQLAPHTAPLAQLRARHGAYFVTGNHEYY 234 Y ++ VN L+PD V +TGD++DG A + +L ++V+GNHE Sbjct: 59 -GLYNNPLLSIVNELAPDAVFLTGDMIDGDESPFVT-MAVVRKLAKEFPVFYVSGNHEGR 116 Query: 235 SNAHEWIE-EVRRLGLTVLMNEHVVLRHDDAGLVLAGVTDYTAHHFDPAHRSDPH----- 288 S +E + ++ + + VL NE LR D A +++AGV D D A + P Sbjct: 117 SAFYEDFKADMEKHHVAVLENERYFLRKDGAAIMVAGVKDPRFVRDDWAEKELPKQVWEE 176 Query: 289 --------AAIADAPDGHPRILLAHQPRSAQAAAEAGFDLQLSGHTHGGQF---FPWNFF 337 A A+ + ILLAH+P DL LSGH HGGQF F Sbjct: 177 EALKEALDEATANLSPDYFTILLAHRPEFWPLYQAYPVDLVLSGHAHGGQFRLPLTEGLF 236 Query: 338 VPLQQ---PYVAGLKRLQGLWVYVSRGTSYWGPPKRLLAPSEITRVRLTAR 385 P Q + AGL G + VSRG RL EI R+ L A+ Sbjct: 237 APGQGFMPKWTAGLHSAGGKSLIVSRGLGNVTKLPRLFNDPEIIRITLKAK 287 >all0251 [R] COG1408 Predicted phosphohydrolases Nos Nostoc sp. PCC 7120 Length = 276 Score = 97.8 bits (242), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 80/279 (28%), Positives = 128/279 (45%), Gaps = 47/279 (16%) Query: 142 AVVEVSVPIANLPAALEGFSIVQISDIHV-GPTIKAPYLQAIVDKVNALSPDVVAITGDL 200 +V +++V IA L A+L+G +V +SD H G + L + N + PD+V +TGD Sbjct: 10 SVEQLTVNIAGLSASLQGKKLVHLSDFHYDGLRLSEEMLAEAIAVSNQVQPDLVLLTGDY 69 Query: 201 VDGSVRQLAPHTAPLAQLRARHGAYFVTGNHEYY--SNAHEWIEEVRRLGLTVLMNEHVV 258 V + + + L +L++ G Y + GNH+ Y ++ E + + + G+ VL NE Sbjct: 70 VTTTPQPIHQLAKRLQKLQSHAGIYAILGNHDLYQKNSKTEITQALTKAGIQVLWNEIAY 129 Query: 259 LRHDDAGLVLAGVTDYTAHHFDPA---HRSDPHAAIADAPDGHPRILLAHQPRSAQAAAE 315 ++ L + G+ DY F+P ++ +P PRI+L H P +A Sbjct: 130 PLGEE--LPIVGIVDYYYREFNPQLLFNQLEPTT---------PRIVLCHNPDTAAMLQG 178 Query: 316 AGFDLQLSGHTHGGQ--------------------------FFPW---NFFVPLQQPYVA 346 DLQLSGHTHGGQ FP ++F+ ++ Sbjct: 179 WRVDLQLSGHTHGGQIVIPGLGAVLPYHKKIVRRVPIKIRRLFPLFFKDYFIVRHAEWLQ 238 Query: 347 GLKRLQGLWVYVSRGTSYWGPPKRLLAPSEITRVRLTAR 385 GL R+ +YV+RG + P RL P E+T + L A Sbjct: 239 GLHRIGKNQLYVNRGLGTY-LPGRLFCPPELTVITLEAE 276 >all0250 [R] COG1408 Predicted phosphohydrolases Nos Nostoc sp. PCC 7120 Length = 275 Score = 95.1 bits (235), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 81/277 (29%), Positives = 129/277 (46%), Gaps = 48/277 (17%) Query: 142 AVVEVSVPIANLPAALEGFSIVQISDIHV-GPTIKAPYLQAIVDKVNALSPDVVAITGDL 200 +V +++V IANL +L+G +VQ+SD H G + L+ + N PD++ +TGD Sbjct: 10 SVDKITVKIANLSPSLQGIKLVQLSDFHYDGLRLSEEMLEEAIAVTNEAEPDLILLTGDY 69 Query: 201 VDGSVRQLAPHTAPLAQLRARHGAYFVTGNHE-YYSNAHEWIEE-VRRLGLTVLMNEHVV 258 V + L L++R+G + V GNH+ +YS++ I + + +G+ VL NE Sbjct: 70 VTDDPAPINQLALRLKYLQSRYGIFAVLGNHDIHYSHSKTSITKALTGIGVNVLWNEIAY 129 Query: 259 LRHDDAGLVLAGVTDYTAHHFDPA---HRSDPHAAIADAPDGHPRILLAHQPRSAQAAAE 315 ++ L + G+ DY + F PA ++ DP+ PRI+L+H P +A+ + Sbjct: 130 PLGNE--LPIVGLADYWSKEFHPASVMNKLDPNT---------PRIVLSHNPDTAKILEQ 178 Query: 316 AGFDLQLSGHTHGGQFF-----------------------PWNFF-------VPLQQPYV 345 DLQLSGHTHGG W F V + Sbjct: 179 WRVDLQLSGHTHGGHIVLPGIGPVVYHYKKLLKKAPKKLRRWVPFLLGDCSKVVRYWEWA 238 Query: 346 AGLKRLQGLWVYVSRGTSYWGPPKRLLAPSEITRVRL 382 GL ++ +YV+RG + P RL P E+T + L Sbjct: 239 QGLHQVTNNQLYVNRGLGTYR-PGRLFCPPEVTVITL 274 >BS_ykuE [R] COG1408 Predicted phosphohydrolases Bsu Bacillus subtilis Length = 287 Score = 88.6 bits (218), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 74/255 (29%), Positives = 113/255 (44%), Gaps = 23/255 (9%) Query: 143 VVEVSVPIANLPAALEGFSIVQISDIHVGPTIKAPYLQAIVDKVNALSPDVVAITGDLVD 202 E ++ + +P +GF IVQ SD H+ L+ ++ +N PD++ TGD++D Sbjct: 41 TTEHTIKSSLIPHGFDGFKIVQFSDAHLSDYFTLEDLKTVILTINESKPDLIVFTGDIID 100 Query: 203 G-SVRQLAPHTAP-LAQLRARHGAYFVTGNHEY--YSNAHEWIEEVRRLGLTVLMNEHVV 258 Q P L +L A G + GNH++ Y A + + G TV N + Sbjct: 101 NPDTYQHHQAVIPLLRKLNAPFGKLCIYGNHDHGGYGTA-VYKSLMTAGGFTVYRNGYQT 159 Query: 259 LR-HDDAGLVLAGVTDYTAHHFDPAHRSDP---HAAIADAPDGHPRILLAHQPRSAQAAA 314 L D + + +A + D+ A P ++ D ILL H+P +A Sbjct: 160 LSLADGSKIEIASLDDFNA--------GKPRFMQGTLSRLSDRLFSILLVHEPDAALKTT 211 Query: 315 EAGFDLQLSGHTHGGQFFPWNFFVPLQQP-----YVAGLKRLQGLWVYVSRGTSYWGPPK 369 + +LQLSGHTHGGQ F+ P+ P Y G+ + +YV+RG P Sbjct: 212 DYPVNLQLSGHTHGGQ-IQLPFYGPIITPPYGKVYTEGMYQTGSTHIYVNRGLGMTRLPL 270 Query: 370 RLLAPSEITRVRLTA 384 R LA EIT L + Sbjct: 271 RFLAKPEITVFTLKS 285