BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0244.p (79 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0448_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Rso... 125 3e-29 VC0902_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Vch ... 118 4e-27 ECs3654_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Ecs... 117 8e-27 ZyqcD_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I EcZ E... 117 9e-27 HI1291_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Hin ... 116 1e-26 yqcD_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Eco Es... 116 1e-26 STM2968_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Sty... 114 4e-26 PM0476_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Pmu ... 113 1e-25 YPO1034_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Ype... 110 6e-25 XF2383_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Xfa ... 106 2e-23 >RSc0448_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Rso Ralstonia solanacearum Length = 145 Score = 125 bits (313), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 60/79 (75%), Positives = 68/79 (86%), Gaps = 1/79 (1%) Query: 1 LGAPIDQERLLKYIIGFREHNEFHEQCVERIFTDILRYCKPQKLAVYARYTRRGGLDINP 60 +GAPI+QE LLKY+I FREHNEFHEQCVERIF DI R C+P KLAVYARYTRRGGLDINP Sbjct: 68 VGAPINQEGLLKYLISFREHNEFHEQCVERIFMDIQRQCRPVKLAVYARYTRRGGLDINP 127 Query: 61 WRSNFSSAKPPSQLRNARQ 79 +R+NF++ P LRNARQ Sbjct: 128 FRTNFNTPW-PDNLRNARQ 145 >VC0902_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Vch Vibrio cholerae Length = 144 Score = 118 bits (295), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 55/78 (70%), Positives = 65/78 (83%), Gaps = 1/78 (1%) Query: 2 GAPIDQERLLKYIIGFREHNEFHEQCVERIFTDILRYCKPQKLAVYARYTRRGGLDINPW 61 GA +++E LL+Y++ FREHNEFHEQCVERIFTDI+RYC+PQ L VYARYTRRGGLDINP+ Sbjct: 68 GAKMNREALLRYLVSFREHNEFHEQCVERIFTDIMRYCQPQSLTVYARYTRRGGLDINPF 127 Query: 62 RSNFSSAKPPSQLRNARQ 79 RS+ SA P R ARQ Sbjct: 128 RSSHQSA-PNHNQRMARQ 144 >ECs3654_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Ecs Escherichia coli O157:H7 Length = 146 Score = 117 bits (292), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 54/78 (69%), Positives = 64/78 (82%), Gaps = 2/78 (2%) Query: 2 GAPIDQERLLKYIIGFREHNEFHEQCVERIFTDILRYCKPQKLAVYARYTRRGGLDINPW 61 G ID+E+LL+Y++ FR HNEFHEQCVERIF D+LR+C+P+KL+VYARYTRRGGLDINPW Sbjct: 71 GRQIDREKLLRYLVSFRHHNEFHEQCVERIFNDLLRFCQPEKLSVYARYTRRGGLDINPW 130 Query: 62 RSNFSSAKPPSQLRNARQ 79 RSN S PS R RQ Sbjct: 131 RSN--SDFVPSTTRLVRQ 146 >ZyqcD_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I EcZ Escherichia coli O157:H7 EDL933 Length = 145 Score = 117 bits (292), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 54/78 (69%), Positives = 64/78 (82%), Gaps = 2/78 (2%) Query: 2 GAPIDQERLLKYIIGFREHNEFHEQCVERIFTDILRYCKPQKLAVYARYTRRGGLDINPW 61 G ID+E+LL+Y++ FR HNEFHEQCVERIF D+LR+C+P+KL+VYARYTRRGGLDINPW Sbjct: 70 GRQIDREKLLRYLVSFRHHNEFHEQCVERIFNDLLRFCQPEKLSVYARYTRRGGLDINPW 129 Query: 62 RSNFSSAKPPSQLRNARQ 79 RSN S PS R RQ Sbjct: 130 RSN--SDFVPSTTRLVRQ 145 >HI1291_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Hin Haemophilus influenzae Length = 144 Score = 116 bits (291), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 53/79 (67%), Positives = 65/79 (82%), Gaps = 2/79 (2%) Query: 1 LGAPIDQERLLKYIIGFREHNEFHEQCVERIFTDILRYCKPQKLAVYARYTRRGGLDINP 60 +G I+QE+LL+Y++ FR+HNEFHEQCVERIF D++ Y KP+KL VYARYTRRGGLDINP Sbjct: 68 VGKKINQEKLLRYVVSFRQHNEFHEQCVERIFCDLMHYAKPEKLTVYARYTRRGGLDINP 127 Query: 61 WRSNFSSAKPPSQLRNARQ 79 +RSNF + P LR ARQ Sbjct: 128 FRSNFENL--PENLRLARQ 144 >yqcD_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Eco Escherichia coli K12 Length = 145 Score = 116 bits (291), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 54/78 (69%), Positives = 64/78 (82%), Gaps = 2/78 (2%) Query: 2 GAPIDQERLLKYIIGFREHNEFHEQCVERIFTDILRYCKPQKLAVYARYTRRGGLDINPW 61 G ID+E+LL+Y++ FR HNEFHEQCVERIF D+LR+C+P+KL+VYARYTRRGGLDINPW Sbjct: 70 GRQIDREKLLRYLVSFRHHNEFHEQCVERIFNDLLRFCQPEKLSVYARYTRRGGLDINPW 129 Query: 62 RSNFSSAKPPSQLRNARQ 79 RSN S PS R RQ Sbjct: 130 RSN--SDFVPSTTRLVRQ 145 >STM2968_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Sty Salmonella typhimurium LT2 Length = 145 Score = 114 bits (286), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 53/78 (67%), Positives = 63/78 (80%), Gaps = 2/78 (2%) Query: 2 GAPIDQERLLKYIIGFREHNEFHEQCVERIFTDILRYCKPQKLAVYARYTRRGGLDINPW 61 G ID+E+LL+Y++ FR HNEFHEQCVERIF DILR+C+P+ L+VYARYTRRGGLDINPW Sbjct: 70 GRKIDREKLLRYLVSFRHHNEFHEQCVERIFNDILRFCQPETLSVYARYTRRGGLDINPW 129 Query: 62 RSNFSSAKPPSQLRNARQ 79 RSN P+ R ARQ Sbjct: 130 RSNTDFV--PATGRLARQ 145 >PM0476_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Pmu Pasteurella multocida Length = 142 Score = 113 bits (283), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 53/78 (67%), Positives = 63/78 (80%), Gaps = 2/78 (2%) Query: 2 GAPIDQERLLKYIIGFREHNEFHEQCVERIFTDILRYCKPQKLAVYARYTRRGGLDINPW 61 G ID+E+LL+YII FR+HNEFHEQCVERIF D++++ KP KL VYARYTRRGGLDINP+ Sbjct: 67 GKQIDREKLLRYIISFRQHNEFHEQCVERIFCDLMQFAKPDKLTVYARYTRRGGLDINPF 126 Query: 62 RSNFSSAKPPSQLRNARQ 79 RSNF + P R ARQ Sbjct: 127 RSNFEAV--PDNQRLARQ 142 >YPO1034_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Ype Yersinia pestis Length = 142 Score = 110 bits (276), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 47/63 (74%), Positives = 54/63 (85%) Query: 2 GAPIDQERLLKYIIGFREHNEFHEQCVERIFTDILRYCKPQKLAVYARYTRRGGLDINPW 61 G ID E LL+Y++ FR HNEFHEQCVERIF DI+R+C+P+ L VYARYTRRGGLDINPW Sbjct: 67 GPQIDHEALLRYLVSFRHHNEFHEQCVERIFNDIMRFCQPETLTVYARYTRRGGLDINPW 126 Query: 62 RSN 64 RSN Sbjct: 127 RSN 129 >XF2383_2 [R] COG0780 Enzyme related to GTP cyclohydrolase I Xfa Xylella fastidiosa 9a5c Length = 138 Score = 106 bits (264), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 51/79 (64%), Positives = 56/79 (70%) Query: 1 LGAPIDQERLLKYIIGFREHNEFHEQCVERIFTDILRYCKPQKLAVYARYTRRGGLDINP 60 G PID E LL+Y I FR H EFHEQCVERIF D+L+ C PQ LAV ARYTRRGGLDINP Sbjct: 60 FGVPIDHEGLLRYFISFRHHAEFHEQCVERIFQDVLQRCSPQCLAVEARYTRRGGLDINP 119 Query: 61 WRSNFSSAKPPSQLRNARQ 79 R+ A P S R+ RQ Sbjct: 120 LRTTSEMAWPISVFRDPRQ 138