BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0189.p (248 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4543 [S] COG1496 Uncharacterized conserved protein Pae Pseudom... 255 6e-68 yfiH [S] COG1496 Uncharacterized conserved protein Eco Escherich... 253 2e-67 ZyfiH [S] COG1496 Uncharacterized conserved protein EcZ Escheric... 249 3e-66 ECs3456 [S] COG1496 Uncharacterized conserved protein Ecs Escher... 249 3e-66 STM2661 [S] COG1496 Uncharacterized conserved protein Sty Salmon... 242 5e-64 YPO3276 [S] COG1496 Uncharacterized conserved protein Ype Yersin... 234 2e-61 PM1718 [S] COG1496 Uncharacterized conserved protein Pmu Pasteur... 228 7e-60 HI0175 [S] COG1496 Uncharacterized conserved protein Hin Haemoph... 226 4e-59 RSc1629 [S] COG1496 Uncharacterized conserved protein Rso Ralsto... 224 2e-58 VC0710 [S] COG1496 Uncharacterized conserved protein Vch Vibrio ... 223 3e-58 >PA4543 [S] COG1496 Uncharacterized conserved protein Pae Pseudomonas aeruginosa Length = 242 Score = 255 bits (652), Expect = 6e-68, Method: Compositional matrix adjust. Identities = 144/247 (58%), Positives = 166/247 (67%), Gaps = 12/247 (4%) Query: 4 LLPDWTAPANIGALTTLRAGGFSPAPYDDGQGGPGLNLGLHVEDDAALVARNRALLGRLL 63 L PDW APA + A T R+GG S AP+D LNLG HV+DD V NR L L Sbjct: 5 LTPDWPAPARVRACVTTRSGGVSQAPFD------SLNLGAHVDDDPRAVEENRRRLTERL 58 Query: 64 PSEPAWLTQVHGVTVLDAAALPDQP-TADACISSTPGAVCVMMTADCLPVLFCDRAGSVV 122 P+WL QVHGVTV++A P + ADA S+ PG C +MTADCLP LFCDR+G+ V Sbjct: 59 ECRPSWLDQVHGVTVVEAD--PSRVLRADASWSAMPGVACTIMTADCLPALFCDRSGTRV 116 Query: 123 GAAHAGWRGLAAGVLEQTVAAARARGAQEIMAWLGPAIGPDHFEVGGEVRQAFVAQQAAA 182 AAHAGWRGLAAGVLE TV + G E++ WLGPAIGP FEVGGEVR AFVA A A Sbjct: 117 AAAHAGWRGLAAGVLEATVDSLGVPG-DELLVWLGPAIGPRAFEVGGEVRDAFVAAHAEA 175 Query: 183 AAAFRDYPGRPGKYLADIYQLARQRLAAVGVTEVSGGGLCTVADT-RFYSYRRDKTTGRM 241 +AF PG+++ADIY+LAR RL A GVT V GGG CT +DT RFYSYRR TGR Sbjct: 176 RSAFVP-SANPGRFMADIYRLARIRLGAHGVTAVHGGGFCTFSDTARFYSYRRSSRTGRF 234 Query: 242 ASLVWLK 248 ASLVWL+ Sbjct: 235 ASLVWLQ 241 >yfiH [S] COG1496 Uncharacterized conserved protein Eco Escherichia coli K12 Length = 243 Score = 253 bits (647), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 140/250 (56%), Positives = 165/250 (66%), Gaps = 14/250 (5%) Query: 2 ELLLPDWTAPANIGALTTLRAGGFSPAPYDDGQGGPGLNLGLHVEDDAALVARNRALL-- 59 +L++P W P + A ++ R GG S PYD LNLG H D+ V NR L Sbjct: 3 KLIVPQWPQPKGVAACSSTRIGGVSLPPYDS------LNLGAHCGDNPDHVEENRKRLFA 56 Query: 60 GRLLPSEPAWLTQVHGVTVLDAAALP-DQPTADACISSTPGAVCVMMTADCLPVLFCDRA 118 LPS+P WL QVHG VL P ADA S+TPG VC +MTADCLPVLFC+RA Sbjct: 57 AGNLPSKPVWLEQVHGKDVLKLTGEPYASKRADASYSNTPGTVCAVMTADCLPVLFCNRA 116 Query: 119 GSVVGAAHAGWRGLAAGVLEQTVAAARARGAQEIMAWLGPAIGPDHFEVGGEVRQAFVAQ 178 G+ V AAHAGWRGL AGVLE+TV+ A + I+AWLGPAIGP FEVGGEVR+AF+A Sbjct: 117 GTEVAAAHAGWRGLCAGVLEETVSCF-ADNPENILAWLGPAIGPRAFEVGGEVREAFMAV 175 Query: 179 QAAAAAAFRDYPGRPGKYLADIYQLARQRLAAVGVTEVSGGGLCTVADTR-FYSYRRDKT 237 A A+AAF + KYLADIYQLARQRLA VGV ++ GG CT + F+SYRRDKT Sbjct: 176 DAKASAAFIQH---GDKYLADIYQLARQRLANVGVEQIFGGDRCTYTENETFFSYRRDKT 232 Query: 238 TGRMASLVWL 247 TGRMAS +WL Sbjct: 233 TGRMASFIWL 242 >ZyfiH [S] COG1496 Uncharacterized conserved protein EcZ Escherichia coli O157:H7 EDL933 Length = 243 Score = 249 bits (637), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 138/250 (55%), Positives = 164/250 (65%), Gaps = 14/250 (5%) Query: 2 ELLLPDWTAPANIGALTTLRAGGFSPAPYDDGQGGPGLNLGLHVEDDAALVARNRALL-- 59 +L++P W P + A ++ R GG S PYD LNLG H D+ V NR L Sbjct: 3 KLIVPQWPLPKGVAACSSTRIGGVSLPPYD------SLNLGAHCGDNPDHVEENRKRLFA 56 Query: 60 GRLLPSEPAWLTQVHGVTVLDAAALP-DQPTADACISSTPGAVCVMMTADCLPVLFCDRA 118 LPS+P WL QVHG VL+ P ADA S+TPG VC +MTADCLPVLFC+RA Sbjct: 57 AGNLPSKPVWLEQVHGKDVLNLTGEPYASKRADASYSNTPGRVCAVMTADCLPVLFCNRA 116 Query: 119 GSVVGAAHAGWRGLAAGVLEQTVAAARARGAQEIMAWLGPAIGPDHFEVGGEVRQAFVAQ 178 G+ V AAHAGWRGL AGVLE+TV+ A + I+AWLGPAIGP FEVG EVR+AF+A Sbjct: 117 GTEVAAAHAGWRGLCAGVLEETVSCF-ADNPENILAWLGPAIGPRAFEVGAEVREAFMAV 175 Query: 179 QAAAAAAFRDYPGRPGKYLADIYQLARQRLAAVGVTEVSGGGLCTVADTR-FYSYRRDKT 237 A A+ AF + KYLADIYQLARQRLA VGV ++ GG CT + F+SYRRDKT Sbjct: 176 DAEASTAFIQH---GDKYLADIYQLARQRLANVGVEQIFGGDRCTYTENETFFSYRRDKT 232 Query: 238 TGRMASLVWL 247 TGRMAS +WL Sbjct: 233 TGRMASFIWL 242 >ECs3456 [S] COG1496 Uncharacterized conserved protein Ecs Escherichia coli O157:H7 Length = 243 Score = 249 bits (637), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 138/250 (55%), Positives = 164/250 (65%), Gaps = 14/250 (5%) Query: 2 ELLLPDWTAPANIGALTTLRAGGFSPAPYDDGQGGPGLNLGLHVEDDAALVARNRALL-- 59 +L++P W P + A ++ R GG S PYD LNLG H D+ V NR L Sbjct: 3 KLIVPQWPLPKGVAACSSTRIGGVSLPPYD------SLNLGAHCGDNPDHVEENRKRLFA 56 Query: 60 GRLLPSEPAWLTQVHGVTVLDAAALP-DQPTADACISSTPGAVCVMMTADCLPVLFCDRA 118 LPS+P WL QVHG VL+ P ADA S+TPG VC +MTADCLPVLFC+RA Sbjct: 57 AGNLPSKPVWLEQVHGKDVLNLTGEPYASKRADASYSNTPGRVCAVMTADCLPVLFCNRA 116 Query: 119 GSVVGAAHAGWRGLAAGVLEQTVAAARARGAQEIMAWLGPAIGPDHFEVGGEVRQAFVAQ 178 G+ V AAHAGWRGL AGVLE+TV+ A + I+AWLGPAIGP FEVG EVR+AF+A Sbjct: 117 GTEVAAAHAGWRGLCAGVLEETVSCF-ADNPENILAWLGPAIGPRAFEVGAEVREAFMAV 175 Query: 179 QAAAAAAFRDYPGRPGKYLADIYQLARQRLAAVGVTEVSGGGLCTVADTR-FYSYRRDKT 237 A A+ AF + KYLADIYQLARQRLA VGV ++ GG CT + F+SYRRDKT Sbjct: 176 DAEASTAFIQH---GDKYLADIYQLARQRLANVGVEQIFGGDRCTYTENETFFSYRRDKT 232 Query: 238 TGRMASLVWL 247 TGRMAS +WL Sbjct: 233 TGRMASFIWL 242 >STM2661 [S] COG1496 Uncharacterized conserved protein Sty Salmonella typhimurium LT2 Length = 243 Score = 242 bits (618), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 135/249 (54%), Positives = 159/249 (63%), Gaps = 14/249 (5%) Query: 3 LLLPDWTAPANIGALTTLRAGGFSPAPYDDGQGGPGLNLGLHVEDDAALVARNRALL--G 60 L++P W P + A ++ R GG S PYD LNLG H D+ V NR L Sbjct: 4 LIVPQWPLPKGVAACSSTRIGGVSLPPYD------SLNLGAHCGDNPEHVEENRKRLFAA 57 Query: 61 RLLPSEPAWLTQVHGVTVLDAAALP-DQPTADACISSTPGAVCVMMTADCLPVLFCDRAG 119 LPS+P WL QVHG VL P ADA S+TPG VC +MTADCLPVLFC+R G Sbjct: 58 GNLPSKPVWLEQVHGKNVLRLTGEPYASKRADASYSNTPGTVCAVMTADCLPVLFCNREG 117 Query: 120 SVVGAAHAGWRGLAAGVLEQTVAAARARGAQEIMAWLGPAIGPDHFEVGGEVRQAFVAQQ 179 + V AAHAGWRGL GVLE+TV A + I+AWLGPAIGP FEVG EVR AF+A+ Sbjct: 118 TEVAAAHAGWRGLCEGVLEETVTCF-ADKPENIIAWLGPAIGPTAFEVGPEVRDAFLAKD 176 Query: 180 AAAAAAFRDYPGRPGKYLADIYQLARQRLAAVGVTEVSGGGLCTVADTR-FYSYRRDKTT 238 A A +AF + K+LADIYQLARQRLA GV V GG CT +++ F+SYRRDKTT Sbjct: 177 AQADSAFLPH---GEKFLADIYQLARQRLANTGVEHVYGGDRCTFSESETFFSYRRDKTT 233 Query: 239 GRMASLVWL 247 GRMAS +WL Sbjct: 234 GRMASFIWL 242 >YPO3276 [S] COG1496 Uncharacterized conserved protein Ype Yersinia pestis Length = 243 Score = 234 bits (596), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 135/249 (54%), Positives = 154/249 (61%), Gaps = 14/249 (5%) Query: 3 LLLPDWTAPANIGALTTLRAGGFSPAPYDDGQGGPGLNLGLHVEDDAALVARNRALLGR- 61 L+LPDW PA + A +T R GG S +PYD LNLG HV D A V NR LL Sbjct: 4 LILPDWPMPARVRACSTTRHGGVSVSPYDS------LNLGTHVGDVATHVDANRQLLREQ 57 Query: 62 -LLPSEPAWLTQVHGVTVLDAAALPDQPT-ADACISSTPGAVCVMMTADCLPVLFCDRAG 119 LP P WL QVHG VL T ADA S G VC +MTADCLPVLFC AG Sbjct: 58 ACLPQMPVWLDQVHGTRVLTLEGRSVSNTQADAVYSRVVGQVCAVMTADCLPVLFCSLAG 117 Query: 120 SVVGAAHAGWRGLAAGVLEQTVAAARARGAQEIMAWLGPAIGPDHFEVGGEVRQAFVAQQ 179 V AAHAGWRGL +GVLE TVA A +MAWLGPAIGP FEVG +V+QAF++ Sbjct: 118 DEVAAAHAGWRGLCSGVLEHTVAQFNA-APSSLMAWLGPAIGPQQFEVGEDVKQAFISID 176 Query: 180 AAAAAAFRDYPGRPGKYLADIYQLARQRLAAVGVTEVSGGGLCTVADT-RFYSYRRDKTT 238 A +A AF + KYLADIY LAR RL A G+ + GG CTV + +F+SYRRD T Sbjct: 177 AKSALAFTPF---GSKYLADIYLLARLRLQAAGIQAIYGGNRCTVTEKQQFFSYRRDGIT 233 Query: 239 GRMASLVWL 247 GRMASL+WL Sbjct: 234 GRMASLIWL 242 >PM1718 [S] COG1496 Uncharacterized conserved protein Pmu Pasteurella multocida Length = 244 Score = 228 bits (582), Expect = 7e-60, Method: Compositional matrix adjust. Identities = 120/251 (47%), Positives = 155/251 (61%), Gaps = 10/251 (3%) Query: 1 MELLLPDWTAPANIGALTTLRAGGFSPAPYDDGQGGPGLNLGLHVEDDAALVARNRALL- 59 M++L P+W AP ++ A +TL GG+S PY LNLG HV DD V RNR LL Sbjct: 1 MDVLKPNWHAPTHVRAFSTLTQGGYSSPPY------ASLNLGDHVGDDPKTVERNRTLLV 54 Query: 60 -GRLLPSEPAWLTQVHGVTVLDAAALPDQPTADACISSTPGAVCVMMTADCLPVLFCDRA 118 LP P +L Q+H VL ADA S+ VC++MTADCLPVL + A Sbjct: 55 DTLKLPQFPRFLNQIHSTHVLTLPTTAHNFEADAVYSNQANQVCLVMTADCLPVLLTNTA 114 Query: 119 GSVVGAAHAGWRGLAAGVLEQTVAAARARGAQEIMAWLGPAIGPDHFEVGGEVRQAFVAQ 178 G+ V AAHAGWRGL G+LE+TV A++++AWLGPAI HF+VG EVR+ F+ Q Sbjct: 115 GNEVAAAHAGWRGLCHGILERTVEKFNT-PAEQLIAWLGPAISQPHFQVGKEVREQFIQQ 173 Query: 179 QAAAAAAFRDYPGRPGKYLADIYQLARQRLAAVGVTEVSGGGLCTVADT-RFYSYRRDKT 237 A AF P +YLAD+Y LA QRL +G+++VSGG CT A +F+SYRR++ Sbjct: 174 DPDAERAFLPDPDVKERYLADLYLLATQRLNKLGISQVSGGDYCTFAQKEKFFSYRREQR 233 Query: 238 TGRMASLVWLK 248 TGRMASL+W + Sbjct: 234 TGRMASLIWFE 244 >HI0175 [S] COG1496 Uncharacterized conserved protein Hin Haemophilus influenzae Length = 244 Score = 226 bits (575), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 116/251 (46%), Positives = 152/251 (60%), Gaps = 10/251 (3%) Query: 1 MELLLPDWTAPANIGALTTLRAGGFSPAPYDDGQGGPGLNLGLHVEDDAALVARNRALLG 60 M+ + P+W P NI A TT R GG S APY NLG HV D+ + V NR LL Sbjct: 1 MQAINPNWNVPKNIHAFTTTREGGVSLAPY------LSFNLGDHVGDNKSAVKTNRTLLV 54 Query: 61 RL--LPSEPAWLTQVHGVTVLDAAALPDQPTADACISSTPGAVCVMMTADCLPVLFCDRA 118 LP P +LTQ H V+ ADA ++ P VCV+MTADCLPVLF + Sbjct: 55 EKFGLPQTPIFLTQTHSTRVIQLPYSGQNLEADAVYTNVPNQVCVVMTADCLPVLFTTTS 114 Query: 119 GSVVGAAHAGWRGLAAGVLEQTVAAARARGAQEIMAWLGPAIGPDHFEVGGEVRQAFVAQ 178 G+ V A HAGWRGL GVLE+TV +A+ ++I+AW GPAIGP F+VG +V + FV Sbjct: 115 GNEVAATHAGWRGLCDGVLEETVKYFQAK-PEDIIAWFGPAIGPKAFQVGIDVVEKFVVV 173 Query: 179 QAAAAAAFRDYPGRPGKYLADIYQLARQRLAAVGVTEVSGGGLCTVADT-RFYSYRRDKT 237 A AF+ GKYL+++YQ+A QRL +G+T++ GG CT + +F+SYRRD Sbjct: 174 DEKAKLAFQPDAIEEGKYLSNLYQIATQRLNNLGITQIYGGNHCTFNEKEKFFSYRRDNQ 233 Query: 238 TGRMASLVWLK 248 TGRMAS++W + Sbjct: 234 TGRMASVIWFE 244 >RSc1629 [S] COG1496 Uncharacterized conserved protein Rso Ralstonia solanacearum Length = 267 Score = 224 bits (570), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 142/260 (54%), Positives = 170/260 (65%), Gaps = 16/260 (6%) Query: 2 ELLLPDWTAPANIGALTTLRAGGFSPAPYDDGQGGPGLNLGL-HVEDDAALVARNRALLG 60 + ++PDW AP ++ AL+T R GG S PY G PG HV D V +NR LL Sbjct: 6 DWIVPDWPAPPSVRALSTTRQGGVSTGPYGLAGGLPGGLNLGRHVGDGPDAVTQNRRLLR 65 Query: 61 RLLPSEPAWLTQVHGVTVLDA-AALPDQPTADACISSTPGAVCVMMTADCLPVLFCDRAG 119 +LP+EPAW+ QVHG V D LP ADA I+++PG VCV+MTADCLPVL CD G Sbjct: 66 AVLPAEPAWMEQVHGTVVADLDQPLPAPVVADAAIAASPGRVCVVMTADCLPVLLCDARG 125 Query: 120 SVVGAAHAGWRGLAAGVLEQTVA----AARARGAQ---EIMAWLGPAIGPDHFEVGGEVR 172 VGAAHAGWRGL +GV+EQTV A RA G + +AWLGPAIGPD FEVG EVR Sbjct: 126 VTVGAAHAGWRGLCSGVIEQTVERMTDALRACGQEADPTWLAWLGPAIGPDCFEVGAEVR 185 Query: 173 QAFV-----AQQAAAAAAFRDYPGRPGKYLADIYQLARQRLAAVGVTEVSGGGLCTVAD- 226 QAF+ + A AAF + GK+LAD+Y LAR RLA G +V GGGLCT+ D Sbjct: 186 QAFIDAARPDELPATRAAFAEGAAD-GKFLADLYALARLRLARAGCRDVHGGGLCTMTDA 244 Query: 227 TRFYSYRRDKTTGRMASLVW 246 RFYSYRRD+TTGRMA+L+W Sbjct: 245 ERFYSYRRDRTTGRMATLIW 264 >VC0710 [S] COG1496 Uncharacterized conserved protein Vch Vibrio cholerae Length = 240 Score = 223 bits (568), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 124/250 (49%), Positives = 151/250 (60%), Gaps = 15/250 (6%) Query: 3 LLLPDWTAPANIGALTTLRAGGFSPAPYDDGQGGPGLNLGLHVEDDAALVARNRALL--G 60 ++LP+W AP + A ++ R GGFS Y GLNLG+HV DD LV RNR L Sbjct: 1 MILPNWNAPKQVKAFSSTRHGGFSQGVYQ------GLNLGMHVGDDPVLVLRNRQSLVAT 54 Query: 61 RLLPSEPAWLTQVHGVTVLDAAALPDQP-TADACISSTPGAVCVMMTADCLPVLFCDRAG 119 +PS P WL Q H VLD A +Q AD I+STP VC MTADCLPVL +R G Sbjct: 55 SAMPSSPIWLNQTHSTVVLDVDAPTEQVLDADGLITSTPNVVCSAMTADCLPVLMTNRTG 114 Query: 120 SVVGAAHAGWRGLAAGVLEQTVAAARARGAQEIMAWLGPAIGPDHFEVGGEVRQAFVAQQ 179 + V A HAGWRGL G++E T AAR G ++M WLGPAIG FEVG +V AFVA Sbjct: 115 TQVAAVHAGWRGLVNGIVEHT--AARMSG--DVMVWLGPAIGAQAFEVGEDVFAAFVAHH 170 Query: 180 AAAAAAFRDYPGRPGKYLADIYQLARQRLAAVGVTEVSGGGLCTVAD-TRFYSYRRDKTT 238 A AF + GK+LAD+ QL + RL +G+ +V GLCT D RFYSYRRD T Sbjct: 171 PQAEYAFTPR-AQQGKWLADMSQLVKLRLQELGIEQVFDSGLCTYQDAERFYSYRRDGVT 229 Query: 239 GRMASLVWLK 248 GR A+ +WL+ Sbjct: 230 GRQAAFIWLE 239