BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0141.p (229 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1210 [R] COG0670 Integral membrane protein, interacts with Ft... 338 8e-93 yccA [R] COG0670 Integral membrane protein, interacts with FtsH ... 139 5e-33 ZyccA [R] COG0670 Integral membrane protein, interacts with FtsH... 137 2e-32 ECs1054 [R] COG0670 Integral membrane protein, interacts with Ft... 137 2e-32 VC1358 [R] COG0670 Integral membrane protein, interacts with Fts... 136 4e-32 NMB2020 [R] COG0670 Integral membrane protein, interacts with Ft... 125 1e-28 NMA0420 [R] COG0670 Integral membrane protein, interacts with Ft... 125 1e-28 STM1085 [R] COG0670 Integral membrane protein, interacts with Ft... 123 3e-28 PA2604 [R] COG0670 Integral membrane protein, interacts with Fts... 121 1e-27 Cj0236c [R] COG0670 Integral membrane protein, interacts with Ft... 119 4e-27 >RSc1210 [R] COG0670 Integral membrane protein, interacts with FtsH Rso Ralstonia solanacearum Length = 233 Score = 338 bits (866), Expect = 8e-93, Method: Compositional matrix adjust. Identities = 173/231 (74%), Positives = 202/231 (87%), Gaps = 3/231 (1%) Query: 2 NNLDTT-FGHSTTS--LATRNRVLRNTYWLLALSMIPTVLGAWLGVQLHFSLFAGSPMIS 58 N L+T FG S T+ LA RNRVLRNTYWLLALSMIPT+LGAW+GV F+L AG P++ Sbjct: 3 NQLNTYGFGASGTAGALAVRNRVLRNTYWLLALSMIPTILGAWIGVATGFNLMAGRPLMG 62 Query: 59 FVLFLAIAFGFFYAIEKTKNSGLGVAFLLGFTFFMGLMLSRLIEFTLGFSNGAGLIMTAF 118 F++F+ +AFGFFYAIE+ KNSG+GVA LLGFTFFMGLMLSRLI LGFSNGA LIMTAF Sbjct: 63 FLIFMGVAFGFFYAIERFKNSGMGVALLLGFTFFMGLMLSRLIGMILGFSNGAALIMTAF 122 Query: 119 GGTAIIFCGMATIATVSKRDFSGLGKWLFAGVLVILVAALANIFLQLPALQLTISVVAIA 178 GGTA IF MAT+ATVSKRDFSGLGKWLF GVLV++V ++ANI+LQLP++ LTISV+AIA Sbjct: 123 GGTATIFAVMATVATVSKRDFSGLGKWLFMGVLVLIVGSVANIWLQLPSMMLTISVLAIA 182 Query: 179 IFSAYILFDVQQVVNGGETNYISATLAIYLDVYNVFANLLSILGIVGGNRD 229 IFSAYIL+DVQ++VNGGETNY++ATLAIYLDVYNVF NLL+ILGI GGNR+ Sbjct: 183 IFSAYILYDVQRIVNGGETNYVTATLAIYLDVYNVFTNLLAILGIFGGNRN 233 >yccA [R] COG0670 Integral membrane protein, interacts with FtsH Eco Escherichia coli K12 Length = 219 Score = 139 bits (350), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 92/222 (41%), Positives = 133/222 (59%), Gaps = 13/222 (5%) Query: 10 HSTTSLATRNRVLRNTYWLLALSMIPTVLGAWLGVQLHFSLFAGSPMISFVLFLAIAFGF 69 H TSL + ++VLRNTY+LL+L++ + + A L P +L L +G Sbjct: 9 HDRTSLLSTHKVLRNTYFLLSLTLAFSAITATASTVLML------PSPGLILTLVGMYGL 62 Query: 70 FYAIEKTKNSGLGVAFLLGFTFFMGLMLSRLIEFTLGFSNGAG-LIMTAFGGTAIIF-CG 127 + KT N G+ FT F+G +L ++ L S G G +I A GGTA++F C Sbjct: 63 MFLTYKTANKPTGIISAFAFTGFLGYILGPILNTYL--SAGMGDVIAMALGGTALVFFCC 120 Query: 128 MATIATVSKRDFSGLGKWLFAGVLVILVAALANIFLQLPALQLTISVVAIAIFSAYILFD 187 A + T +++D S LG L AG++V+L+ +ANIFLQLPAL L IS V I I S ILF+ Sbjct: 121 SAYVLT-TRKDMSFLGGMLMAGIVVVLIGMVANIFLQLPALHLAISAVFILISSGAILFE 179 Query: 188 VQQVVNGGETNYISATLAIYLDVYNVFANLLSILGIVGGNRD 229 +++GGETNYI AT+++Y+ +YN+F +LLSILG +RD Sbjct: 180 TSNIIHGGETNYIRATVSLYVSLYNIFVSLLSILGF--ASRD 219 >ZyccA [R] COG0670 Integral membrane protein, interacts with FtsH EcZ Escherichia coli O157:H7 EDL933 Length = 219 Score = 137 bits (344), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 91/222 (40%), Positives = 132/222 (59%), Gaps = 13/222 (5%) Query: 10 HSTTSLATRNRVLRNTYWLLALSMIPTVLGAWLGVQLHFSLFAGSPMISFVLFLAIAFGF 69 H TSL + ++VLRNTY+LL+L++ + + A L P +L L +G Sbjct: 9 HDRTSLLSTHKVLRNTYFLLSLTLAFSAITATASTVLML------PSPGLILTLVGMYGL 62 Query: 70 FYAIEKTKNSGLGVAFLLGFTFFMGLMLSRLIEFTLGFSNGAG-LIMTAFGGTAIIF-CG 127 + K N G+ FT F+G +L ++ L S G G +I A GGTA++F C Sbjct: 63 MFLTYKMANKPTGIISAFAFTGFLGYILGPILNTYL--SAGMGDVIAMALGGTALVFFCC 120 Query: 128 MATIATVSKRDFSGLGKWLFAGVLVILVAALANIFLQLPALQLTISVVAIAIFSAYILFD 187 A + T +++D S LG L AG++V+L+ +ANIFLQLPAL L IS V I I S ILF+ Sbjct: 121 SAYVLT-TRKDMSFLGGMLMAGIVVVLIGMVANIFLQLPALHLAISAVFILISSGAILFE 179 Query: 188 VQQVVNGGETNYISATLAIYLDVYNVFANLLSILGIVGGNRD 229 +++GGETNYI AT+++Y+ +YN+F +LLSILG +RD Sbjct: 180 TSNIIHGGETNYIRATVSLYVSLYNIFVSLLSILGF--ASRD 219 >ECs1054 [R] COG0670 Integral membrane protein, interacts with FtsH Ecs Escherichia coli O157:H7 Length = 219 Score = 137 bits (344), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 91/222 (40%), Positives = 132/222 (59%), Gaps = 13/222 (5%) Query: 10 HSTTSLATRNRVLRNTYWLLALSMIPTVLGAWLGVQLHFSLFAGSPMISFVLFLAIAFGF 69 H TSL + ++VLRNTY+LL+L++ + + A L P +L L +G Sbjct: 9 HDRTSLLSTHKVLRNTYFLLSLTLAFSAITATASTVLML------PSPGLILTLVGMYGL 62 Query: 70 FYAIEKTKNSGLGVAFLLGFTFFMGLMLSRLIEFTLGFSNGAG-LIMTAFGGTAIIF-CG 127 + K N G+ FT F+G +L ++ L S G G +I A GGTA++F C Sbjct: 63 MFLTYKMANKPTGIISAFAFTGFLGYILGPILNTYL--SAGMGDVIAMALGGTALVFFCC 120 Query: 128 MATIATVSKRDFSGLGKWLFAGVLVILVAALANIFLQLPALQLTISVVAIAIFSAYILFD 187 A + T +++D S LG L AG++V+L+ +ANIFLQLPAL L IS V I I S ILF+ Sbjct: 121 SAYVLT-TRKDMSFLGGMLMAGIVVVLIGMVANIFLQLPALHLAISAVFILISSGAILFE 179 Query: 188 VQQVVNGGETNYISATLAIYLDVYNVFANLLSILGIVGGNRD 229 +++GGETNYI AT+++Y+ +YN+F +LLSILG +RD Sbjct: 180 TSNIIHGGETNYIRATVSLYVSLYNIFVSLLSILGF--ASRD 219 >VC1358 [R] COG0670 Integral membrane protein, interacts with FtsH Vch Vibrio cholerae Length = 223 Score = 136 bits (342), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 81/209 (38%), Positives = 130/209 (62%), Gaps = 5/209 (2%) Query: 19 NRVLRNTYWLLALSMIPTVLGAWLGVQLHFSLFAGSPMISFVLFLAIAFGFFYAIEKTKN 78 N+VL+NTY+LL+++++ + + A + + S P+++ V+ LA F+ + K N Sbjct: 19 NKVLKNTYFLLSMTLVTSAIAAMATMAIGIS-----PIVALVMQLAAIGILFFVMPKAIN 73 Query: 79 SGLGVAFLLGFTFFMGLMLSRLIEFTLGFSNGAGLIMTAFGGTAIIFCGMATIATVSKRD 138 S G+ + FT MG L ++ F NG +I A G T ++F G++ SK+D Sbjct: 74 SSSGLVWTFVFTGLMGGALGPMLNFYAAMPNGPIVIAQALGLTGMVFLGLSAYTITSKKD 133 Query: 139 FSGLGKWLFAGVLVILVAALANIFLQLPALQLTISVVAIAIFSAYILFDVQQVVNGGETN 198 FS + +LFAG+++++VAAL NIF+ L IS V+ +FS +ILFD ++V G ETN Sbjct: 134 FSFMRNFLFAGLIIVIVAALINIFVGSTVAHLAISSVSALVFSGFILFDTSRIVRGEETN 193 Query: 199 YISATLAIYLDVYNVFANLLSILGIVGGN 227 YISAT+++YL++ N+F +LLSILGI+ N Sbjct: 194 YISATISMYLNILNLFTSLLSILGIMNNN 222 >NMB2020 [R] COG0670 Integral membrane protein, interacts with FtsH Nme Neisseria meningitidis MC58 Length = 227 Score = 125 bits (313), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 76/207 (36%), Positives = 127/207 (61%), Gaps = 2/207 (0%) Query: 12 TTSLATRNRVLRNTYWLLALSMIPTVLGAWLGVQLHFSLFA--GSPMISFVLFLAIAFGF 69 T ++N VL+ TY LL S IP GA L F+ +A GS I F + LA +G Sbjct: 9 TAHTVSKNTVLQKTYRLLGFSFIPASAGAALAANAGFNFYAAFGSRWIGFAVVLAFFYGM 68 Query: 70 FYAIEKTKNSGLGVAFLLGFTFFMGLMLSRLIEFTLGFSNGAGLIMTAFGGTAIIFCGMA 129 + IEK + S GV L+ FTF MG+++ ++++ L ++GA ++ A TA +F M+ Sbjct: 69 IHFIEKNRYSNTGVTLLMVFTFGMGVLIGPVLQYALHIADGAKIVGIAAAMTAAVFLTMS 128 Query: 130 TIATVSKRDFSGLGKWLFAGVLVILVAALANIFLQLPALQLTISVVAIAIFSAYILFDVQ 189 +A ++ D + LG++L G ++++VA +AN+FL +PAL LTIS + S I++ V+ Sbjct: 129 ALARRTRLDMNALGRFLTVGAVILMVAVVANLFLGIPALALTISAGFVLFSSLMIMWQVR 188 Query: 190 QVVNGGETNYISATLAIYLDVYNVFAN 216 V++GGE ++ISA L +++ +YN+F++ Sbjct: 189 TVIDGGEDSHISAALTLFISLYNIFSS 215 >NMA0420 [R] COG0670 Integral membrane protein, interacts with FtsH NmA Neisseria meningitidis Z2491 Length = 227 Score = 125 bits (313), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 76/207 (36%), Positives = 127/207 (61%), Gaps = 2/207 (0%) Query: 12 TTSLATRNRVLRNTYWLLALSMIPTVLGAWLGVQLHFSLFA--GSPMISFVLFLAIAFGF 69 T ++N VL+ TY LL S IP GA L F+ +A GS I F + LA +G Sbjct: 9 TAHTVSKNTVLQKTYRLLGFSFIPASAGAALAANAGFNFYAAFGSRWIGFAVVLAFFYGM 68 Query: 70 FYAIEKTKNSGLGVAFLLGFTFFMGLMLSRLIEFTLGFSNGAGLIMTAFGGTAIIFCGMA 129 + IEK + S GV L+ FTF MG+++ ++++ L ++GA ++ A TA +F M+ Sbjct: 69 IHFIEKNRYSNTGVTLLMVFTFGMGVLIGPVLQYALHIADGAKIVGIAAAMTAAVFLTMS 128 Query: 130 TIATVSKRDFSGLGKWLFAGVLVILVAALANIFLQLPALQLTISVVAIAIFSAYILFDVQ 189 +A ++ D + LG++L G ++++VA +AN+FL +PAL LTIS + S I++ V+ Sbjct: 129 ALARRTRLDMNALGRFLTVGAVILMVAVVANLFLGIPALALTISAGFVLFSSLMIMWQVR 188 Query: 190 QVVNGGETNYISATLAIYLDVYNVFAN 216 V++GGE ++ISA L +++ +YN+F++ Sbjct: 189 TVIDGGEDSHISAALTLFISLYNIFSS 215 >STM1085 [R] COG0670 Integral membrane protein, interacts with FtsH Sty Salmonella typhimurium LT2 Length = 219 Score = 123 bits (309), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 87/213 (40%), Positives = 129/213 (60%), Gaps = 13/213 (6%) Query: 19 NRVLRNTYWLLALSMIPTVLGAWLGVQLHFSLFAGSPMISFVLFLAIAFGFFYAIEKTKN 78 ++VLRNTY+LL+L++ + + A L P +L L +G + KT N Sbjct: 18 HKVLRNTYFLLSLTLALSAITATASTVLML------PSPGLILTLVGMYGLMFLTYKTAN 71 Query: 79 SGLGVAFLLGFTFFMGLMLSRLIEFTLGFSNGAG-LIMTAFGGTAIIF-CGMATIATVSK 136 +G+ FT F+G +L ++ L S G G +I A GGTA++F C A + T ++ Sbjct: 72 KPVGILSAFAFTGFLGYILGPILNAYL--SAGMGDVIGLALGGTALVFFCCSAYVLT-TR 128 Query: 137 RDFSGLGKWLFAGVLVILVAALANIFLQLPALQLTISVVAIAIFSAYILFDVQQVVNGGE 196 +D S LG L AG++V+L+ +ANIFLQLPAL L IS V I I S IL++ +++GGE Sbjct: 129 KDMSFLGGMLMAGIVVVLIGMVANIFLQLPALHLAISAVFILISSGAILYETSNIIHGGE 188 Query: 197 TNYISATLAIYLDVYNVFANLLSILGIVGGNRD 229 TNYI AT+++Y+ +YN+F +LLSILG +RD Sbjct: 189 TNYIRATVSLYVSLYNIFVSLLSILGF--ASRD 219 >PA2604 [R] COG0670 Integral membrane protein, interacts with FtsH Pae Pseudomonas aeruginosa Length = 222 Score = 121 bits (304), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 76/207 (36%), Positives = 118/207 (57%), Gaps = 6/207 (2%) Query: 21 VLRNTYWLLALSMIPTVLGAWLGVQLHFSLFAGSPMISFVLFLAIAFGFFYAIEKTKNSG 80 VLRNTY LLAL++ + L A++ Q+ P + + L +G F+ K +NS Sbjct: 21 VLRNTYGLLALTLAFSGLVAYVSQQMRL------PYPNVFVVLIGFYGLFFLTVKLRNSA 74 Query: 81 LGVAFLLGFTFFMGLMLSRLIEFTLGFSNGAGLIMTAFGGTAIIFCGMATIATVSKRDFS 140 G+ T FMG L ++ LG NG +I +AF TA++F G++ +++D S Sbjct: 75 WGLVSTFALTGFMGYTLGPILNMYLGLPNGGSVITSAFAMTALVFFGLSAYVLTTRKDMS 134 Query: 141 GLGKWLFAGVLVILVAALANIFLQLPALQLTISVVAIAIFSAYILFDVQQVVNGGETNYI 200 L ++ AG V+L A L ++F Q+ LQL IS + SA IL+ +++GGE NYI Sbjct: 135 FLSGFITAGFFVLLGAVLVSLFFQISGLQLAISAGFVLFSSAMILYQTSAIIHGGERNYI 194 Query: 201 SATLAIYLDVYNVFANLLSILGIVGGN 227 AT+++Y+ +YN+F +LL I GI GG+ Sbjct: 195 MATISLYVSIYNLFISLLQIFGIAGGD 221 >Cj0236c [R] COG0670 Integral membrane protein, interacts with FtsH Cje Campylobacter jejuni Length = 231 Score = 119 bits (299), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 80/226 (35%), Positives = 125/226 (55%), Gaps = 6/226 (2%) Query: 1 MNNLDTTFGHSTTSLATRNRVL----RNTYWLLALSMIPTVLGAWLGVQLHFSLFAGSPM 56 M+ D + S TR+ L + TY L A S++ +GA++G+ S F S + Sbjct: 1 MSLYDRDYSRSKEFENTRSSELSIFIKQTYQLFAASLLAATVGAYVGIFALASFFIQSQV 60 Query: 57 ISFVLFLAIAFGFFYAIE-KTKNSGLGVAFLLGFTFFMGLMLSRLIEFTLGFSNGAGLIM 115 ++LF A+ G +A++ K + + L + L GFTF GL L+ L+ L G +I Sbjct: 61 TFWILF-AVEIGLLFALQWKKREAPLNLVLLFGFTFCSGLTLTPLLISVLALPAGGIIIA 119 Query: 116 TAFGGTAIIFCGMATIATVSKRDFSGLGKWLFAGVLVILVAALANIFLQLPALQLTISVV 175 AF T + F G++ A +K+DF+ +GK LF ++VI+ A+L N+F Q + L IS V Sbjct: 120 QAFALTTVAFAGLSVFAMNTKKDFTVMGKALFIVLIVIVAASLLNLFFQSSIVNLAISAV 179 Query: 176 AIAIFSAYILFDVQQVVNGGETNYISATLAIYLDVYNVFANLLSIL 221 A +FS YIL+D Q ++ G I +A+YLD N+F +LL+IL Sbjct: 180 AAILFSFYILYDTQNIIRGNYETPIEGAVALYLDFVNLFVSLLNIL 225