BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0127.p (437 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1226 [F] COG0104 Adenylosuccinate synthase Rso Ralstonia sola... 619 e-177 PA4938 [F] COG0104 Adenylosuccinate synthase Pae Pseudomonas aer... 600 e-171 NMA1024 [F] COG0104 Adenylosuccinate synthase NmA Neisseria meni... 565 e-161 NMB0815 [F] COG0104 Adenylosuccinate synthase Nme Neisseria meni... 561 e-159 VC2602 [F] COG0104 Adenylosuccinate synthase Vch Vibrio cholerae 550 e-156 PM0938 [F] COG0104 Adenylosuccinate synthase Pmu Pasteurella mul... 542 e-154 YPO0378 [F] COG0104 Adenylosuccinate synthase Ype Yersinia pestis 541 e-154 purA [F] COG0104 Adenylosuccinate synthase Eco Escherichia coli K12 530 e-150 ECs5153 [F] COG0104 Adenylosuccinate synthase Ecs Escherichia co... 530 e-150 HI1633 [F] COG0104 Adenylosuccinate synthase Hin Haemophilus inf... 529 e-150 >RSc1226 [F] COG0104 Adenylosuccinate synthase Rso Ralstonia solanacearum Length = 446 Score = 619 bits (1595), Expect = e-177, Method: Compositional matrix adjust. Identities = 309/440 (70%), Positives = 368/440 (83%), Gaps = 8/440 (1%) Query: 5 SNAKNVVVIGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLVIGGKKTALQLIPSG 64 S +NVVVIGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTL+IGGKKT L+LIPSG Sbjct: 7 SQGRNVVVIGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLIIGGKKTILRLIPSG 66 Query: 65 IMREGVACYIGNGVVLSVPDLLREIDKLEAAGVEVCSRLKVSDACPLILPYHVALDVARE 124 IMR+GVACYIGNGVVLS L +EID+LE+AGVEV SRL++S+A LILPYH+A+D ARE Sbjct: 67 IMRDGVACYIGNGVVLSPEALFKEIDELESAGVEVKSRLRISEATTLILPYHIAIDKARE 126 Query: 125 AARGADKIGTTGKGIGPAYEDKVARRAIRVADLLNEKRFAEKLLANLDYHNFVLTHYLKT 184 RGA KIGTTG+GIGPAYEDKVARRA+RV DL + FAE+L NLD+HNFVLT YL Sbjct: 127 IKRGAAKIGTTGRGIGPAYEDKVARRALRVQDLFDPAYFAERLRENLDFHNFVLTQYLNH 186 Query: 185 QPVDYQKTLDEALANVPRIKPMVTDVSSDLYAIHKAGGKILFEGAQGSLLDVDHGTYPFV 244 +D+Q+TLDE L R+ PMVTDVS++L+A + AG ++FEGAQG+LLD+DHGTYPFV Sbjct: 187 PALDFQQTLDEMLPYGERLAPMVTDVSAELFAANAAGKNLMFEGAQGTLLDIDHGTYPFV 246 Query: 245 TSSNCVAGNAAAGAGVGPGMLHYIMGITKAYTTRVGSGPFPAELPTDAG-------TGKH 297 TSSNCVAGNAAAGAGVGPG LHYI+GITKAY TRVGSGPFP+EL DA TG Sbjct: 247 TSSNCVAGNAAAGAGVGPGQLHYILGITKAYCTRVGSGPFPSEL-YDADNPARQDPTGVR 305 Query: 298 LASVGHEFGTVTGRARRCGWFDAALLKRSVQINGVSGMCLTKLDVLDGLDSLKLCTGYKL 357 LA+VG EFG+VTGR RR GW DAA L+R++QINGVSG+C+TKLDVLDGL+++KLC GY L Sbjct: 306 LANVGKEFGSVTGRPRRTGWLDAAALRRAIQINGVSGLCMTKLDVLDGLETIKLCVGYML 365 Query: 358 NGKTVDIFPVGAEEAAACEPIYEEMPGWSETTVGAKSLEALPANARAYIKRIEELVGVPI 417 +GK++DI P G++ A C+P+YEE PGW+ +T G K +ALP A+AY+KR+EE+ G+PI Sbjct: 366 DGKSIDILPRGSDAVARCQPVYEEFPGWNTSTFGLKEWDALPETAQAYLKRVEEVAGIPI 425 Query: 418 DMISTGPDREETIVLRHPFK 437 MISTGPDR+ETI+LRHP+K Sbjct: 426 AMISTGPDRDETILLRHPYK 445 >PA4938 [F] COG0104 Adenylosuccinate synthase Pae Pseudomonas aeruginosa Length = 430 Score = 600 bits (1547), Expect = e-171, Method: Compositional matrix adjust. Identities = 292/429 (68%), Positives = 338/429 (78%), Gaps = 2/429 (0%) Query: 8 KNVVVIGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLVIGGKKTALQLIPSGIMR 67 KNVVV+GTQWGDEGKGKIVD LT+ A VVR+QGGHNAGHTLVI G+KT L LIPSGI+R Sbjct: 3 KNVVVLGTQWGDEGKGKIVDLLTEQAAAVVRYQGGHNAGHTLVIDGEKTVLHLIPSGILR 62 Query: 68 EGVACYIGNGVVLSVPDLLREIDKLEAAGVEVCSRLKVSDACPLILPYHVALDVAREAAR 127 EGV C IGNGVVL+ LLREI KLE GV V RL++S +CPLIL YHVALD ARE AR Sbjct: 63 EGVQCLIGNGVVLAPDALLREITKLEEKGVPVRERLRISPSCPLILSYHVALDQAREKAR 122 Query: 128 GADKIGTTGKGIGPAYEDKVARRAIRVADLLNEKRFAEKLLANLDYHNFVLTHYLKTQPV 187 G KIGTTG+GIGPAYEDKVARR +RV DL + +RFA KL LDYHNFVL HY K + Sbjct: 123 GEAKIGTTGRGIGPAYEDKVARRGLRVGDLFHRERFAAKLGELLDYHNFVLQHYYKEPAI 182 Query: 188 DYQKTLDEALANVPRIKPMVTDVSSDLYAIHKAGGKILFEGAQGSLLDVDHGTYPFVTSS 247 D+QKTLDEA+ +KPM+ DV++ L+ + K G I+FEGAQGSLLD+DHGTYP+VTSS Sbjct: 183 DFQKTLDEAMEYAELLKPMMADVAATLHDLRKHGKDIMFEGAQGSLLDIDHGTYPYVTSS 242 Query: 248 NCVAGNAAAGAGVGPGMLHYIMGITKAYTTRVGSGPFPAELPTDAGTGKHLASVGHEFGT 307 N AG A G+G GP L Y++GITKAYTTRVGSGPFP EL D G +LA GHEFG Sbjct: 243 NTTAGGTATGSGFGPLYLDYVLGITKAYTTRVGSGPFPTELFDDVGA--YLAKRGHEFGA 300 Query: 308 VTGRARRCGWFDAALLKRSVQINGVSGMCLTKLDVLDGLDSLKLCTGYKLNGKTVDIFPV 367 TGRARRCGWFDA +L+R+++IN +SG+CLTKLDVLDGLD ++LC GYK V P Sbjct: 301 TTGRARRCGWFDAVILRRAIEINSISGLCLTKLDVLDGLDVVRLCVGYKNADGDVLEAPT 360 Query: 368 GAEEAAACEPIYEEMPGWSETTVGAKSLEALPANARAYIKRIEELVGVPIDMISTGPDRE 427 A+ +P+YEEMPGWSE+TVGAK+LE LPANARAYIKR+EELVG PID+ISTGPDR Sbjct: 361 DADSYIGLQPVYEEMPGWSESTVGAKTLEELPANARAYIKRVEELVGAPIDIISTGPDRN 420 Query: 428 ETIVLRHPF 436 ETI+LRHPF Sbjct: 421 ETIILRHPF 429 >NMA1024 [F] COG0104 Adenylosuccinate synthase NmA Neisseria meningitidis Z2491 Length = 432 Score = 565 bits (1455), Expect = e-161, Method: Compositional matrix adjust. Identities = 287/432 (66%), Positives = 343/432 (79%), Gaps = 4/432 (0%) Query: 7 AKNVVVIGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLVIGGKKTALQLIPSGIM 66 AKNVVVIG QWGDEGKGKIVDWL + A GVVRFQGGHNAGHTLV+GGKKT L+LIPSGI+ Sbjct: 2 AKNVVVIGAQWGDEGKGKIVDWLAEEAGGVVRFQGGHNAGHTLVVGGKKTILRLIPSGIL 61 Query: 67 REGVACYIGNGVVLSVPDLLREIDKLEAAGVE-VCSRLKVSDACPLILPYHVALDVAREA 125 E + C+IG+GVV+S LL EID+L AAGV+ V RLK++ CPLILPYH+ALD AREA Sbjct: 62 HESLDCFIGSGVVVSPEALLGEIDELNAAGVKNVEGRLKIAPTCPLILPYHIALDQAREA 121 Query: 126 ARGADKIGTTGKGIGPAYEDKVARRAIRVADLLNEKRFAEKLLANLDYHNFVLTHYLKTQ 185 +RG KIGTTG+GIGPAYEDKVARRAIR ADLL+ ++ EKL A Y+N L H + Sbjct: 122 SRGKGKIGTTGRGIGPAYEDKVARRAIRAADLLHPEKLREKLDAVFAYYNVQLQHLHNAE 181 Query: 186 PVDYQKTLDEALANVPRIKPMVTDVSSDLYAIHKAGGKILFEGAQGSLLDVDHGTYPFVT 245 V + + PRI PM+TDVS L +K G K+LFEGAQG+LLD+D+GTYPFVT Sbjct: 182 SVKAEDVMAVIEKVAPRITPMITDVSRVLNEKNKNGEKLLFEGAQGALLDIDYGTYPFVT 241 Query: 246 SSNCVAGNAAAGAGVGPGMLHYIMGITKAYTTRVGSGPFPAELPTDAGTGKHLASVGHEF 305 SSNC+AG A+AGAGVGP ML Y++GI KAYTTRVGSGPFP EL + G G LA GHEF Sbjct: 242 SSNCLAGAASAGAGVGPQMLDYVLGIVKAYTTRVGSGPFPTELFDEVGAG--LAERGHEF 299 Query: 306 GTVTGRARRCGWFDAALLKRSVQINGVSGMCLTKLDVLDGLDSLKLCTGYKL-NGKTVDI 364 G+VTGRARRCGWFDAA LKRS+QING+SGMC+TKLDV+DG++++ +C GY+L +G DI Sbjct: 300 GSVTGRARRCGWFDAAALKRSIQINGISGMCITKLDVMDGVETINICVGYELPDGGKTDI 359 Query: 365 FPVGAEEAAACEPIYEEMPGWSETTVGAKSLEALPANARAYIKRIEELVGVPIDMISTGP 424 P G++ AC+PIYE MPGWSE+T G KS +ALPANA+AY+KRIEE+ G P+ ++STGP Sbjct: 360 LPCGSDAVEACKPIYETMPGWSESTFGVKSYDALPANAKAYLKRIEEVCGAPVAIVSTGP 419 Query: 425 DREETIVLRHPF 436 DREETIVL HPF Sbjct: 420 DREETIVLHHPF 431 >NMB0815 [F] COG0104 Adenylosuccinate synthase Nme Neisseria meningitidis MC58 Length = 434 Score = 561 bits (1445), Expect = e-159, Method: Compositional matrix adjust. Identities = 285/432 (65%), Positives = 340/432 (78%), Gaps = 4/432 (0%) Query: 7 AKNVVVIGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLVIGGKKTALQLIPSGIM 66 AKNVVVIG QWGDEGKGKIVDWL + A GVVRFQGGHNAGHTLV+GGKKT L+LIPSGI+ Sbjct: 4 AKNVVVIGAQWGDEGKGKIVDWLAEEAGGVVRFQGGHNAGHTLVVGGKKTILRLIPSGIL 63 Query: 67 REGVACYIGNGVVLSVPDLLREIDKLEAAGVE-VCSRLKVSDACPLILPYHVALDVAREA 125 E + C+IG+GVV+S LL EID+L AAGV+ V RLK++ CPLILPYH+ALD AREA Sbjct: 64 HESLDCFIGSGVVVSPEALLGEIDELNAAGVKNVEGRLKIAPTCPLILPYHIALDQAREA 123 Query: 126 ARGADKIGTTGKGIGPAYEDKVARRAIRVADLLNEKRFAEKLLANLDYHNFVLTHYLKTQ 185 +RG KIGTTG+GIGPAYEDKVARRAIR ADLL+ ++ EKL A L Y+N L H + Sbjct: 124 SRGKGKIGTTGRGIGPAYEDKVARRAIRAADLLHPEKLREKLDAVLAYYNVQLQHLHNAE 183 Query: 186 PVDYQKTLDEALANVPRIKPMVTDVSSDLYAIHKAGGKILFEGAQGSLLDVDHGTYPFVT 245 PV + + PRI PM+TDVS L +K G K+LFEGAQG+LLD+D+GTYPFVT Sbjct: 184 PVKAEDVMAVIEKVAPRIAPMITDVSRVLNEKNKNGEKLLFEGAQGALLDIDYGTYPFVT 243 Query: 246 SSNCVAGNAAAGAGVGPGMLHYIMGITKAYTTRVGSGPFPAELPTDAGTGKHLASVGHEF 305 SSNC+AG A+AGAGVGP ML Y++GI KAYTTRVGSGPFP EL + G G LA GHEF Sbjct: 244 SSNCLAGAASAGAGVGPQMLDYVLGIVKAYTTRVGSGPFPTELFDEVGVG--LAERGHEF 301 Query: 306 GTVTGRARRCGWFDAALLKRSVQINGVSGMCLTKLDVLDGLDSLKLCTGYKL-NGKTVDI 364 G+VTGRARRCGWFDAA LKRS+QING+SGMC+TKLDV+DG++++ +C GY+L +G DI Sbjct: 302 GSVTGRARRCGWFDAAALKRSIQINGISGMCITKLDVMDGVETINICVGYELPDGGKTDI 361 Query: 365 FPVGAEEAAACEPIYEEMPGWSETTVGAKSLEALPANARAYIKRIEELVGVPIDMISTGP 424 P G++ C+PIYE MPGW E+T G K ALP NA+AY+KRIEE+ G P+ ++STGP Sbjct: 362 LPCGSDAVETCKPIYETMPGWRESTFGVKDYGALPENAKAYLKRIEEVCGAPVAIVSTGP 421 Query: 425 DREETIVLRHPF 436 DREETIVL HPF Sbjct: 422 DREETIVLHHPF 433 >VC2602 [F] COG0104 Adenylosuccinate synthase Vch Vibrio cholerae Length = 432 Score = 550 bits (1416), Expect = e-156, Method: Compositional matrix adjust. Identities = 268/430 (62%), Positives = 321/430 (74%), Gaps = 3/430 (0%) Query: 8 KNVVVIGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLVIGGKKTALQLIPSGIMR 67 NVVV+GTQWGDEGKGKIVD LT+ A+ VVR+QGGHNAGHTLVI G+KT L LIPSGI+R Sbjct: 3 NNVVVLGTQWGDEGKGKIVDLLTEDAKYVVRYQGGHNAGHTLVIDGQKTVLHLIPSGILR 62 Query: 68 EGVACYIGNGVVLSVPDLLREIDKLEAAGVEVCSRLKVSDACPLILPYHVALDVAREAAR 127 V C IGNGVVLS L++E+ LE GV V RL +S+ACPLILPYHVALD AREAAR Sbjct: 63 NNVKCIIGNGVVLSPEALIKEMSGLEDRGVPVRERLFISEACPLILPYHVALDQAREAAR 122 Query: 128 GADKIGTTGKGIGPAYEDKVARRAIRVADLLNEKRFAEKLLANLDYHNFVLTHYLKTQPV 187 G IGTTG+GIGPAYEDKVARR +RV DL + FAEKL + +HNF L H+ K +PV Sbjct: 123 GKKAIGTTGRGIGPAYEDKVARRGLRVGDLFDMASFAEKLQEVMAFHNFQLEHFYKVEPV 182 Query: 188 DYQKTLDEALANVPRIKPMVTDVSSDLYAIHKAGGKILFEGAQGSLLDVDHGTYPFVTSS 247 Y+ L++A + MV DV+++L A K G KI+FEGAQG+LLD+DHGTYP+VTSS Sbjct: 183 SYEAVLEQAKGYAELLTSMVIDVTNELDAARKRGDKIMFEGAQGTLLDIDHGTYPYVTSS 242 Query: 248 NCVAGNAAAGAGVGPGMLHYIMGITKAYTTRVGSGPFPAELPTDAGTGKHLASVGHEFGT 307 N AG AAG+G GP L YI+GI KAY TRVG+GPFP EL + G HL + GHEFG Sbjct: 243 NTTAGGVAAGSGFGPRHLGYILGIAKAYCTRVGAGPFPTELFDE--VGDHLGTKGHEFGA 300 Query: 308 VTGRARRCGWFDAALLKRSVQINGVSGMCLTKLDVLDGLDSLKLCTGYKL-NGKTVDIFP 366 TGR RRCGWFDA ++R++QIN V+G CLTKLDVLDGL +K+CTGY++ +G ++ P Sbjct: 301 TTGRKRRCGWFDAVAMRRAIQINSVTGFCLTKLDVLDGLKEIKICTGYQMPDGSIAEVSP 360 Query: 367 VGAEEAAACEPIYEEMPGWSETTVGAKSLEALPANARAYIKRIEELVGVPIDMISTGPDR 426 + A+ PI+E MPGWSETT GAK+L LP A YIKRIEEL GVP+D+ISTGPDR Sbjct: 361 MAADAFENVTPIFETMPGWSETTFGAKTLAELPQTALDYIKRIEELTGVPVDIISTGPDR 420 Query: 427 EETIVLRHPF 436 ETI+ HPF Sbjct: 421 NETIIKVHPF 430 >PM0938 [F] COG0104 Adenylosuccinate synthase Pmu Pasteurella multocida Length = 432 Score = 542 bits (1397), Expect = e-154, Method: Compositional matrix adjust. Identities = 260/430 (60%), Positives = 321/430 (74%), Gaps = 3/430 (0%) Query: 8 KNVVVIGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLVIGGKKTALQLIPSGIMR 67 K+VV++G QWGDEGKGKIVD LTD + VVR+QGGHNAGHTL+I G+KT L+LIPSGI+R Sbjct: 3 KSVVILGAQWGDEGKGKIVDLLTDRVKYVVRYQGGHNAGHTLIINGEKTVLRLIPSGILR 62 Query: 68 EGVACYIGNGVVLSVPDLLREIDKLEAAGVEVCSRLKVSDACPLILPYHVALDVAREAAR 127 E V C IGNGVVLS L++E+ +LE+ G+ V RL +S+ACPLILPYHVA+D AREAA Sbjct: 63 ENVTCLIGNGVVLSPAALMQEMGELESRGINVRERLLISEACPLILPYHVAMDHAREAAL 122 Query: 128 GADKIGTTGKGIGPAYEDKVARRAIRVADLLNEKRFAEKLLANLDYHNFVLTHYLKTQPV 187 G +KIGTTG+GIGPAYEDKVARR +RV DL N + FAEKL LDY+NF L +Y K + V Sbjct: 123 GKNKIGTTGRGIGPAYEDKVARRGLRVGDLFNREAFAEKLKTILDYYNFQLVNYYKAEAV 182 Query: 188 DYQKTLDEALANVPRIKPMVTDVSSDLYAIHKAGGKILFEGAQGSLLDVDHGTYPFVTSS 247 D+QKTLD+ +A I MV DV++ L K G ILFEGAQG++LD+DHGTYPFVTSS Sbjct: 183 DFQKTLDDVMAVADIITGMVADVTTMLDKARKNGDNILFEGAQGTMLDIDHGTYPFVTSS 242 Query: 248 NCVAGNAAAGAGVGPGMLHYIMGITKAYTTRVGSGPFPAELPTDAGTGKHLASVGHEFGT 307 N AG A GAG GP L Y++GI KAY TRVG GPF EL + G+ +A G+EFG Sbjct: 243 NTTAGGVATGAGFGPRNLDYVLGIIKAYCTRVGGGPFTTELFDEVGS--EIARKGNEFGA 300 Query: 308 VTGRARRCGWFDAALLKRSVQINGVSGMCLTKLDVLDGLDSLKLCTGYKL-NGKTVDIFP 366 VTGR RRCGWFDA ++R++Q+N +SG C+TKLDVLDG D +K+C YK+ NG +D P Sbjct: 301 VTGRPRRCGWFDAVAIRRAIQLNSISGFCMTKLDVLDGFDEVKICVAYKMPNGDILDYAP 360 Query: 367 VGAEEAAACEPIYEEMPGWSETTVGAKSLEALPANARAYIKRIEELVGVPIDMISTGPDR 426 + A++ EPIYE MPGW E T G + LP R Y+KRIEE+ GVP+D++STGPDR Sbjct: 361 LAAKDWEGVEPIYETMPGWKENTFGVTDVNQLPEACRNYVKRIEEVTGVPVDILSTGPDR 420 Query: 427 EETIVLRHPF 436 ET++LR PF Sbjct: 421 VETMILRDPF 430 >YPO0378 [F] COG0104 Adenylosuccinate synthase Ype Yersinia pestis Length = 432 Score = 541 bits (1395), Expect = e-154, Method: Compositional matrix adjust. Identities = 267/430 (62%), Positives = 323/430 (75%), Gaps = 3/430 (0%) Query: 8 KNVVVIGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLVIGGKKTALQLIPSGIMR 67 KNVVV+GTQWGDEGKGK+VD LT+ A+ VVR+QGGHNAGHTLVI G+KT L LIPSGI+R Sbjct: 3 KNVVVLGTQWGDEGKGKVVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILR 62 Query: 68 EGVACYIGNGVVLSVPDLLREIDKLEAAGVEVCSRLKVSDACPLILPYHVALDVAREAAR 127 E V IGNGVVL+ L++E+ +LEA GV V RL +S+ACPLILPYHVALD ARE AR Sbjct: 63 ENVISIIGNGVVLAPDALMKEMTELEARGVPVRERLLLSEACPLILPYHVALDNAREKAR 122 Query: 128 GADKIGTTGKGIGPAYEDKVARRAIRVADLLNEKRFAEKLLANLDYHNFVLTHYLKTQPV 187 GA IGTTG+GIGPAYEDKVARR +RV+DL N++ FA KL ++YHNF L HY K V Sbjct: 123 GAKAIGTTGRGIGPAYEDKVARRGLRVSDLFNKETFAIKLKEIVEYHNFQLVHYYKEAAV 182 Query: 188 DYQKTLDEALANVPRIKPMVTDVSSDLYAIHKAGGKILFEGAQGSLLDVDHGTYPFVTSS 247 DYQK LD+ LA + MV DVS L K G I+FEGAQG+LLD+DHGTYP+VTSS Sbjct: 183 DYQKVLDDVLAIADILTAMVVDVSELLDNARKQGELIMFEGAQGTLLDIDHGTYPYVTSS 242 Query: 248 NCVAGNAAAGAGVGPGMLHYIMGITKAYTTRVGSGPFPAELPTDAGTGKHLASVGHEFGT 307 N AG A G+G+GP + Y++GI KAY+TRVG+GPFP EL + TG+ L G+E+G Sbjct: 243 NTTAGGVATGSGLGPRYVDYVLGIVKAYSTRVGAGPFPTELNDE--TGEFLRKQGNEYGA 300 Query: 308 VTGRARRCGWFDAALLKRSVQINGVSGMCLTKLDVLDGLDSLKLCTGYKL-NGKTVDIFP 366 TGR+RR GW D ++R+VQIN +SG C+TKLDVLDGL +KLC GY++ +G+ VD P Sbjct: 301 TTGRSRRTGWLDIVAVRRAVQINSLSGFCMTKLDVLDGLKEVKLCVGYRMPDGREVDTTP 360 Query: 367 VGAEEAAACEPIYEEMPGWSETTVGAKSLEALPANARAYIKRIEELVGVPIDMISTGPDR 426 + AE EPIYE MPGWSETT G K LP A YI+R+EEL GVPID+ISTGPDR Sbjct: 361 LAAEGWEGIEPIYETMPGWSETTFGVKEHSKLPQAALNYIQRVEELTGVPIDIISTGPDR 420 Query: 427 EETIVLRHPF 436 +ET++LR PF Sbjct: 421 DETMILRDPF 430 >purA [F] COG0104 Adenylosuccinate synthase Eco Escherichia coli K12 Length = 432 Score = 530 bits (1366), Expect = e-150, Method: Compositional matrix adjust. Identities = 260/430 (60%), Positives = 318/430 (73%), Gaps = 3/430 (0%) Query: 8 KNVVVIGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLVIGGKKTALQLIPSGIMR 67 NVVV+GTQWGDEGKGKIVD LT+ A+ VVR+QGGHNAGHTLVI G+KT L LIPSGI+R Sbjct: 3 NNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILR 62 Query: 68 EGVACYIGNGVVLSVPDLLREIDKLEAAGVEVCSRLKVSDACPLILPYHVALDVAREAAR 127 E V IGNGVVLS L++E+ +LE G+ V RL +S+ACPLIL YHVALD ARE AR Sbjct: 63 ENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKAR 122 Query: 128 GADKIGTTGKGIGPAYEDKVARRAIRVADLLNEKRFAEKLLANLDYHNFVLTHYLKTQPV 187 GA IGTTG+GIGPAYEDKVARR +RV DL +++ FAEKL ++YHNF L +Y K + V Sbjct: 123 GAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAV 182 Query: 188 DYQKTLDEALANVPRIKPMVTDVSSDLYAIHKAGGKILFEGAQGSLLDVDHGTYPFVTSS 247 DYQK LD+ +A + MV DVS L + G ++FEGAQG+LLD+DHGTYP+VTSS Sbjct: 183 DYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSS 242 Query: 248 NCVAGNAAAGAGVGPGMLHYIMGITKAYTTRVGSGPFPAELPTDAGTGKHLASVGHEFGT 307 N AG A G+G+GP + Y++GI KAY+TRVG+GPFP EL + TG+ L G+EFG Sbjct: 243 NTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDE--TGEFLCKQGNEFGA 300 Query: 308 VTGRARRCGWFDAALLKRSVQINGVSGMCLTKLDVLDGLDSLKLCTGYKL-NGKTVDIFP 366 TGR RR GW D ++R+VQ+N +SG CLTKLDVLDGL +KLC Y++ +G+ V P Sbjct: 301 TTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTP 360 Query: 367 VGAEEAAACEPIYEEMPGWSETTVGAKSLEALPANARAYIKRIEELVGVPIDMISTGPDR 426 + A++ EPIYE MPGWSE+T G K LP A YIKRIEEL GVPID+ISTGPDR Sbjct: 361 LAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDR 420 Query: 427 EETIVLRHPF 436 ET++LR PF Sbjct: 421 TETMILRDPF 430 >ECs5153 [F] COG0104 Adenylosuccinate synthase Ecs Escherichia coli O157:H7 Length = 432 Score = 530 bits (1366), Expect = e-150, Method: Compositional matrix adjust. Identities = 260/430 (60%), Positives = 318/430 (73%), Gaps = 3/430 (0%) Query: 8 KNVVVIGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLVIGGKKTALQLIPSGIMR 67 NVVV+GTQWGDEGKGKIVD LT+ A+ VVR+QGGHNAGHTLVI G+KT L LIPSGI+R Sbjct: 3 NNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILR 62 Query: 68 EGVACYIGNGVVLSVPDLLREIDKLEAAGVEVCSRLKVSDACPLILPYHVALDVAREAAR 127 E V IGNGVVLS L++E+ +LE G+ V RL +S+ACPLIL YHVALD ARE AR Sbjct: 63 ENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKAR 122 Query: 128 GADKIGTTGKGIGPAYEDKVARRAIRVADLLNEKRFAEKLLANLDYHNFVLTHYLKTQPV 187 GA IGTTG+GIGPAYEDKVARR +RV DL +++ FAEKL ++YHNF L +Y K + V Sbjct: 123 GAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAV 182 Query: 188 DYQKTLDEALANVPRIKPMVTDVSSDLYAIHKAGGKILFEGAQGSLLDVDHGTYPFVTSS 247 DYQK LD+ +A + MV DVS L + G ++FEGAQG+LLD+DHGTYP+VTSS Sbjct: 183 DYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSS 242 Query: 248 NCVAGNAAAGAGVGPGMLHYIMGITKAYTTRVGSGPFPAELPTDAGTGKHLASVGHEFGT 307 N AG A G+G+GP + Y++GI KAY+TRVG+GPFP EL + TG+ L G+EFG Sbjct: 243 NTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDE--TGEFLCKQGNEFGA 300 Query: 308 VTGRARRCGWFDAALLKRSVQINGVSGMCLTKLDVLDGLDSLKLCTGYKL-NGKTVDIFP 366 TGR RR GW D ++R+VQ+N +SG CLTKLDVLDGL +KLC Y++ +G+ V P Sbjct: 301 TTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTP 360 Query: 367 VGAEEAAACEPIYEEMPGWSETTVGAKSLEALPANARAYIKRIEELVGVPIDMISTGPDR 426 + A++ EPIYE MPGWSE+T G K LP A YIKRIEEL GVPID+ISTGPDR Sbjct: 361 LAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDR 420 Query: 427 EETIVLRHPF 436 ET++LR PF Sbjct: 421 TETMILRDPF 430 >HI1633 [F] COG0104 Adenylosuccinate synthase Hin Haemophilus influenzae Length = 432 Score = 529 bits (1362), Expect = e-150, Method: Compositional matrix adjust. Identities = 254/430 (59%), Positives = 319/430 (74%), Gaps = 3/430 (0%) Query: 8 KNVVVIGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLVIGGKKTALQLIPSGIMR 67 K+VV++G QWGDEGKGKIVD LTD + VVR+QGGHNAGHTL+I G+KT L+LIPSG++ Sbjct: 3 KSVVILGAQWGDEGKGKIVDLLTDRVKYVVRYQGGHNAGHTLIINGEKTVLRLIPSGMLH 62 Query: 68 EGVACYIGNGVVLSVPDLLREIDKLEAAGVEVCSRLKVSDACPLILPYHVALDVAREAAR 127 V C IGNGVV+S L++E+ +LE+ G++V RL +S+ACPLILPYHVA+D AREAA Sbjct: 63 PNVTCLIGNGVVVSPEALMKEMGELESRGIKVRERLLISEACPLILPYHVAMDHAREAAL 122 Query: 128 GADKIGTTGKGIGPAYEDKVARRAIRVADLLNEKRFAEKLLANLDYHNFVLTHYLKTQPV 187 G IGTTG+GIGPAYEDKVARR +RV DL N++ FAEKL L+Y+NF L +Y K +PV Sbjct: 123 GKKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKEAFAEKLKNILEYYNFQLVNYYKVEPV 182 Query: 188 DYQKTLDEALANVPRIKPMVTDVSSDLYAIHKAGGKILFEGAQGSLLDVDHGTYPFVTSS 247 DYQKTLD+ +A I MV D+++ L K G ILFEGAQG++LD+DHGTYP+VTSS Sbjct: 183 DYQKTLDDVMAIADVITGMVADITTILDTARKNGEHILFEGAQGTMLDIDHGTYPYVTSS 242 Query: 248 NCVAGNAAAGAGVGPGMLHYIMGITKAYTTRVGSGPFPAELPTDAGTGKHLASVGHEFGT 307 N AG A G+G GP L Y++GI KAY TRVG GPF EL D G +A G+EFG Sbjct: 243 NTTAGGVATGSGFGPRNLDYVLGIIKAYCTRVGGGPFTTELFDDVGA--EIARKGNEFGA 300 Query: 308 VTGRARRCGWFDAALLKRSVQINGVSGMCLTKLDVLDGLDSLKLCTGYKL-NGKTVDIFP 366 VTGR RRCGWFDA ++R++Q+N +SG C+TKLDVLDG D +K+C YK+ NG+ V+ P Sbjct: 301 VTGRPRRCGWFDAVAIRRAIQLNSISGFCMTKLDVLDGFDEVKICVAYKMPNGEIVEYAP 360 Query: 367 VGAEEAAACEPIYEEMPGWSETTVGAKSLEALPANARAYIKRIEELVGVPIDMISTGPDR 426 + A++ EPIYE +PGW E T + LP N YIKRIEE+ GVPID++STGPDR Sbjct: 361 LAAKDWEGVEPIYETLPGWKENTFRITDVNKLPQNCINYIKRIEEVTGVPIDILSTGPDR 420 Query: 427 EETIVLRHPF 436 ET++LR PF Sbjct: 421 VETMILREPF 430