BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0113.p (274 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VCA0034 [T] COG1639 Predicted signal transduction protein Vch Vi... 149 6e-36 TM0854 [T] COG1639 Predicted signal transduction protein Tma The... 95 2e-19 PA0356 [T] COG1639 Predicted signal transduction protein Pae Pse... 76 9e-14 TP0073 Non COG 68 2e-11 PA5346_2 [T] COG1639 Predicted signal transduction protein Pae P... 66 1e-10 Cj0248 [T] COG1639 Predicted signal transduction protein Cje Cam... 61 2e-09 PA0758 [T] COG1639 Predicted signal transduction protein Pae Pse... 60 6e-09 >VCA0034 [T] COG1639 Predicted signal transduction protein Vch Vibrio cholerae Length = 290 Score = 149 bits (377), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 77/224 (34%), Positives = 135/224 (60%), Gaps = 6/224 (2%) Query: 1 MNL--EALFQQQTALPSIPKVVREVIESFNNESVSIEEIAKKLAADQVLSAKILRLANSS 58 MN+ + + LP + KV++E+++ N V +++KK+ DQ+L+A++LR+ANS+ Sbjct: 13 MNMVKNTMLNRLNELPRLSKVLQELLDMANQPDVDFHQLSKKITLDQILTARLLRMANSA 72 Query: 59 YYHVSRTIGTVDDAVLMLGFMTVRTLVVSTGMAGSFKKLPGVDLKLFWRYSLDTALVAKW 118 Y+ + I TV+DA++ +G +VRTLVV++ ++ +F K+ +DL +W + +TAL+A Sbjct: 73 YFGGNGHIATVNDAIIRVGIESVRTLVVASVLSSTFPKIETLDLNDYWTNTFETALIASK 132 Query: 119 LAKRGKLNSDFAFTVGLMHAIGQLVMHAGMP-EQALQVDKVAGPLDARRLDVERKSFGYD 177 +A++ L+ FT G++H IG+L++H MP E +L K+A +D L + + G Sbjct: 133 IAEQVGLDKSETFTTGVLHNIGELMIHTLMPTEASLIQQKIAQGMDP--LSAQEEVLGIS 190 Query: 178 FADVGAELARRWRFPDEFAKVIEAFPQPLQGEFDP-FAAIVHLA 220 +GA LA+ W+FP E I+ F +P + E P A +H A Sbjct: 191 APRIGAMLAKEWKFPSEMVDAIKHFDEPREAEISPKLAVAIHFA 234 >TM0854 [T] COG1639 Predicted signal transduction protein Tma Thermotoga maritima Length = 285 Score = 94.7 bits (234), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 70/217 (32%), Positives = 111/217 (51%), Gaps = 12/217 (5%) Query: 13 LPSIPKVVREVIESFNNESVSIEEIAKKLAADQVLSAKILRLANSSYYHVSRTIGTVDDA 72 LPS VV+ +I + S E+A L D LSA++L+LANS+YY V R I T+ +A Sbjct: 16 LPSPNVVVQRIIAVCSKPDASSTEVANTLMMDASLSARVLKLANSAYYGVPRKITTLSEA 75 Query: 73 VLMLGFMTVRTLVVSTGMAGS-FKK-LPGVDLKLFWRYSLDTALVAKWLAKR-GKLNSDF 129 V++LGF TVR L +S FK G+D + W + + +A+ ++ +A+ G + Sbjct: 76 VMILGFKTVRNLALSVFTYDMVFKNSSSGIDREKLWEHFIASAIASETVAETMGYPLKEE 135 Query: 130 AFTVGLMHAIGQLVMHAGMPEQALQVDKVAGPLDARRLDVERKSFGYDFADVGAELARRW 189 F GL+H +G++V + K+A +D+E + ++VGA+L R+W Sbjct: 136 IFIAGLLHDLGKVVYDLLFSDILETEAKIAQKTKKNLIDIEEELGIPPHSEVGAKLLRKW 195 Query: 190 RFPD------EFAKVIEAFPQPLQGEFDPFAAIVHLA 220 FPD EF +E P L F ++VH+ Sbjct: 196 NFPDLLVLSAEFHHNVEGNPNEL---FVNQVSMVHIG 229 >PA0356 [T] COG1639 Predicted signal transduction protein Pae Pseudomonas aeruginosa Length = 274 Score = 75.9 bits (185), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 52/169 (30%), Positives = 83/169 (49%), Gaps = 3/169 (1%) Query: 34 IEEIAKKLAADQVLSAKILRLANSSYYHVSRTIGTVDDAVLMLGFMTVRTLVVSTGMAGS 93 ++ IA+ ++ D LS +L+L NS ++ ++ I ++ AV +LG +V L+ + + G Sbjct: 22 LKNIARLISQDPGLSGALLKLVNSPFFGLANRITSIQRAVNLLGSRSVINLINAQSIKGE 81 Query: 94 FKKLPGVDLKLFWRYSLDTALVAKWLAKR-GKLNSDFAFTVGLMHAIGQLVMHAGMPE-Q 151 V L FW + D A+ LAKR G + D A+ +GL H G +M P Sbjct: 82 MSDDTIVTLNRFWDTAQDVAMSCLSLAKRIGYESVDEAYALGLFHNCGIPLMLKRFPHYM 141 Query: 152 ALQVDKVAGPLDARR-LDVERKSFGYDFADVGAELARRWRFPDEFAKVI 199 A+ + A D RR +D E + + A VG AR WR P+ + I Sbjct: 142 AVLEEAYAAASDERRVVDTENRVLNTNHAVVGYYTARSWRLPEHVCEAI 190 >TP0073 Non COG Length = 513 Score = 68.2 bits (165), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 53/220 (24%), Positives = 99/220 (45%), Gaps = 11/220 (5%) Query: 13 LPSIPKVVREVIESFNNESVSIEEIAKKLAADQVLSAKILRLANSSYYHVSRTIGTVDDA 72 +P +P + E+ + N V + +I ++ D L +L+L NS+ + +++ + +A Sbjct: 254 IPQLPSKLLEIQRAIENPDVQLSDIVALISQDVALVTDLLKLVNSARFGMNKRCLDISEA 313 Query: 73 VLMLGFMTVRTLVVSTGMAGSFKKLPGVDLKLFWRYSLDTALVAKWLAKRGKLNSDFA-- 130 V +G ++ L+ S G AG + + K W + T A LAK + A Sbjct: 314 VKRVGLRGLQNLLYSVG-AGRVLQSTDDERKQLWNQAYRTGYFALGLAKATGDQALIADS 372 Query: 131 FTVGLMHAIGQLVMHAGMPEQALQVDKVAGP--LDARRLDVERKSFGYDFADVGAELARR 188 + GL+H +G++V + PE +++ ++ + LD G+ A++GA LA+R Sbjct: 373 YICGLLHNLGEVVFTSAYPEMLIKLTEIQAERNIPPHVLDTIMSDVGH--AEIGAALAQR 430 Query: 189 WRFPDEFAKVI---EAFPQPLQGEFDPFAAIVHLAAWRAR 225 W P+ I P + E+ P + V A R Sbjct: 431 WNLPEPVINTIRFHHNLPHAPE-EYKPLISTVAFANMTIR 469 >PA5346_2 [T] COG1639 Predicted signal transduction protein Pae Pseudomonas aeruginosa Length = 293 Score = 65.9 bits (159), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 61/255 (23%), Positives = 109/255 (42%), Gaps = 10/255 (3%) Query: 7 FQQQTALPSIPKVVREVIESFNNESVSIEEIAKKLAADQVLSAKILRLANSSYYHVSRTI 66 +Q +P +P+ +++I+ + + S+++I + D L+A+++ A S YY I Sbjct: 13 LEQTIEIPPLPQTAQKIIKLRVDPNASVDDITGLVETDPALAAQVVSWAASPYYAAPGKI 72 Query: 67 GTVDDAVL-MLGFMTVRTLV--VSTGMAGSFKKLPGVDLKLFWRYSLDTALVAKWLA--- 120 +V+DA++ +LGF V L ++ G + S K +W+ ++ TA V + L Sbjct: 73 RSVEDAIVRVLGFDLVINLALGLALGKSLSLPKDQPQQATPYWQQAIYTAAVIEGLTRAM 132 Query: 121 -KRGKLNSDFAFTVGLMHAIGQLVM-HAGMPEQALQVDKVAGPLDARRLDVERKSFGYDF 178 + + S ++ GL+H G LV+ H P +L + +E+ G Sbjct: 133 PRELRPESGLSYLGGLLHNFGYLVLAHVFPPHFSLICRHLEVNPHLGHAYIEQHLLGITR 192 Query: 179 ADVGAELARRWRFPDEFAKVIEAFPQPLQGEFDPFAAIVHLAAWRARAHENQYSDEELAA 238 +GA L R W PD+ + P P A +L R N + Sbjct: 193 EQIGAWLMRVWDMPDDLYCALRFQQDP--SYTGPNAVYANLICLTNRLLRNSGIGDGTQQ 250 Query: 239 TFPTEVAERLGVRLE 253 P + ERLG+ E Sbjct: 251 AIPAALYERLGITPE 265 >Cj0248 [T] COG1639 Predicted signal transduction protein Cje Campylobacter jejuni Length = 285 Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 47/197 (23%), Positives = 92/197 (46%), Gaps = 7/197 (3%) Query: 4 EALFQQQTALPSIPKVVREVIESFNNESVSIE--EIAKKLAADQVLSAKILRLANSSYYH 61 E L + LP +P V ++ + + + +IE ++A+ +++D +++AK+L+LANS YY Sbjct: 7 ELLLKSVEVLPPLPDTVSKLRKYVSEANSNIETMKVAEIISSDPLMTAKLLQLANSPYYG 66 Query: 62 VSRTIGTVDDAVLMLGFMTVRTLVVSTGMAGSFK---KLPGVDLKLFWRYSLDTA-LVAK 117 +R I T++ + +LG + +V++ + +FK G++ + F + + A +A Sbjct: 67 FTREITTINQVITLLGVGNIINIVMADSIRDNFKIDVSPYGLNTQNFLKTCNEEATFIAN 126 Query: 118 WLAKRGKLNSDFAFTVGLMHAIGQLVMHAGMPEQALQVDKVAGPLDARRLDVERKSF-GY 176 WL K S ++ +G ++ + + D +A L + F G Sbjct: 127 WLNDEDKKLSHLLVPCAMLLRLGIVIFSNFLIQNHKDKDFLAFLNKNENLALAENEFLGV 186 Query: 177 DFADVGAELARRWRFPD 193 D L RW F D Sbjct: 187 DHISFLGFLLHRWNFDD 203 >PA0758 [T] COG1639 Predicted signal transduction protein Pae Pseudomonas aeruginosa Length = 278 Score = 60.1 bits (144), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 43/144 (29%), Positives = 70/144 (48%), Gaps = 4/144 (2%) Query: 3 LEALFQQQTALPSIPKVVREVIESFNNESVSIEEIAKKLAADQVLSAKILRLANSSYYHV 62 + A+ Q + LP++P+V +V E+ + VSI+ ++K + D L+A+I+R+ NS Sbjct: 13 IRAIDQDELVLPTLPEVALQVREAAEDPDVSIQALSKVIGNDAALTARIIRVVNSPLLRS 72 Query: 63 SRTIGTVDDAVLMLGFMTVRTLVVSTGMAGSFKKLPG-VDLKL--FWRYSLDTALVAKWL 119 + I + A+ LG L M F+ VD K+ W S + A + L Sbjct: 73 PKEITDLQMAISRLGINYTCNLATGLAMEQMFQATTDVVDRKMREVWNKSTEIAGICHVL 132 Query: 120 AKR-GKLNSDFAFTVGLMHAIGQL 142 A+ +L D A GL+H IG L Sbjct: 133 ARHYTRLAPDQATLAGLVHQIGVL 156