BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0002.p (417 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1177 [GEPR] COG0477 Permeases of the major facilitator superf... 156 7e-38 CAP0049 [GEPR] COG0477 Permeases of the major facilitator superf... 152 2e-36 PA4622 [GEPR] COG0477 Permeases of the major facilitator superfa... 141 4e-33 mlr4214 [GEPR] COG0477 Permeases of the major facilitator superf... 132 1e-30 BMEI0181 [GEPR] COG0477 Permeases of the major facilitator super... 131 3e-30 SMc03237 [GEPR] COG0477 Permeases of the major facilitator super... 128 2e-29 AGc4819 [GEPR] COG0477 Permeases of the major facilitator superf... 122 2e-27 all0371 [GEPR] COG0477 Permeases of the major facilitator superf... 99 2e-20 CC0403 [GEPR] COG0477 Permeases of the major facilitator superfa... 89 2e-17 PA2701 [GEPR] COG0477 Permeases of the major facilitator superfa... 75 4e-13 >RSp1177 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 424 Score = 156 bits (395), Expect = 7e-38, Method: Compositional matrix adjust. Identities = 112/214 (52%), Positives = 140/214 (65%), Gaps = 10/214 (4%) Query: 7 DAAADASPEPPPPLRH----HTPFKLFWCASVASTIALQMQIVAVGWQVYQLTHSAMDLG 62 DA + P P L H + F+LFW A +++T A QM VAVGWQ+Y LT SA LG Sbjct: 4 DAGLSSPPAPAQTLSHAPFAYPAFRLFWLARLSTTFAYQMFGVAVGWQIYDLTRSAYVLG 63 Query: 63 IVGLVQFIPSLILVFVVGHVADRFDRRNVARVSALVEALAAATLAAGSLGGWLNREIIFV 122 +VGL QF+PS++LV GH+ADR+DRR V R+ +EAL AA LAA +L G + + IFV Sbjct: 64 LVGLAQFLPSVVLVLASGHIADRYDRRRVVRICQAIEALVAAMLAAATLTGHASIQPIFV 123 Query: 123 IVAVIGAGRAFSKPTMSALLPSLMSPRQLPGAVAGSASATQFAIIIGPALGGFLYVAGPA 182 V VIGA RAF PT+ ALLPSL+ P LP AVA S+SA Q II+GPA+GGFLYVAG Sbjct: 124 FVVVIGAMRAFETPTLQALLPSLVPPAALPRAVALSSSAGQTGIILGPAVGGFLYVAGAP 183 Query: 183 VVYASSCVLFTLCSLLLSLIRRPACGQADRGQPV 216 VVYA++ LF L +L+ AC + R PV Sbjct: 184 VVYATAAGLFVLAHVLV------ACVRTGRAAPV 211 >CAP0049 [GEPR] COG0477 Permeases of the major facilitator superfamily Cac Clostridium acetobutylicum Length = 408 Score = 152 bits (383), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 74/169 (43%), Positives = 109/169 (64%) Query: 31 CASVASTIALQMQIVAVGWQVYQLTHSAMDLGIVGLVQFIPSLILVFVVGHVADRFDRRN 90 A V+S A QM VA+GWQ+Y LTHSA LG++GLVQF+P L+L VGH++DR+DRR Sbjct: 20 TARVSSNFAYQMLTVAIGWQMYSLTHSAFYLGLIGLVQFLPMLVLSLFVGHISDRYDRRK 79 Query: 91 VARVSALVEALAAATLAAGSLGGWLNREIIFVIVAVIGAGRAFSKPTMSALLPSLMSPRQ 150 + +S LV+ + A LA G+ GW+ +E ++V I +F P M ALLP+++ + Sbjct: 80 IVSISQLVQGICIALLAFGNYNGWITKESFLIMVFFIALAHSFEGPPMQALLPNIVERKI 139 Query: 151 LPGAVAGSASATQFAIIIGPALGGFLYVAGPAVVYASSCVLFTLCSLLL 199 P A A +SA+QFA+I+GP G LY G +++Y+ + L L S+L+ Sbjct: 140 FPKASALVSSASQFAVIVGPGFAGILYSFGASLIYSITAGLLILASVLI 188 >PA4622 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 403 Score = 141 bits (355), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 96/228 (42%), Positives = 128/228 (56%), Gaps = 5/228 (2%) Query: 13 SPEPPPPLRHHTPFKLFWCASVASTIALQMQIVAVGWQVYQLTHSAMDLGIVGLVQFIPS 72 S +P LRH PF FW A V + QM VA+GW +Y+LT + +DLG+VGLV+F+P Sbjct: 2 SSQPSSLLRHR-PFLAFWLARVCTASGFQMLTVAIGWHIYELTGNVLDLGLVGLVEFLPR 60 Query: 73 LILVFVVGHVADRFDRRNVARVSALVEALAAATLAAGSLGGWLNREIIFVIVAVIGAGRA 132 ++ + GHVADR+DRR +A + +AL A L G+ G + R +IFV+ +G RA Sbjct: 61 VLFMLHTGHVADRYDRRRIAALCQAGQALVAVALVLGAASGEITRNMIFVLAFALGTARA 120 Query: 133 FSKPTMSALLPSLMSPRQLPGAVAGSASATQFAIIIGPALGGFLYVAGPAVVYASSCVLF 192 F PT ALLP+L+ P AVA SASA Q A I PALGG LY G + VY + L+ Sbjct: 121 FEMPTTQALLPNLVPAGLFPRAVAASASAMQAATIAAPALGGLLYAFGASWVYVPTATLY 180 Query: 193 TL-CSLLLSLIRRP---ACGQADRGQPVLGLRWPGLHPQQASHLRRDL 236 L C L LSL R G+A + G+R+ P + DL Sbjct: 181 VLACVLTLSLPVRNQPLTQGKATLDSLLAGIRFIRSRPDIFGAISLDL 228 >mlr4214 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 412 Score = 132 bits (333), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 86/210 (40%), Positives = 117/210 (55%), Gaps = 7/210 (3%) Query: 11 DASPEPPPPLRHHTPFKLFWCASVASTIALQMQIVAVGWQVYQLTHSAMDLGIVGLVQFI 70 SPE H F +W A +T A + VAVGWQ+Y LT DLGIVG+VQF+ Sbjct: 5 QTSPEQRYAAFRHKAFLSYWTARFLTTFATMVVSVAVGWQMYDLTRDPFDLGIVGIVQFL 64 Query: 71 PSLILVFVVGHVADRFDRRNVARVSALVEALAAATLAAG---SLGGWLNREIIFVIVAVI 127 PSL+LV V G VADRF RR + ++ +VEA+ A L A S+ G L IF ++A+ Sbjct: 65 PSLLLVLVTGAVADRFGRRLIMALAVVVEAICALALLALTLRSISGPLP---IFCVLAMF 121 Query: 128 GAGRAFSKPTMSALLPSLMSPRQLPGAVAGSASATQFAIIIGPALGGFLYVAGPAVVYAS 187 G RAF P ++L +L+ P A+A ++SA Q A I+GP GG LY P V Y + Sbjct: 122 GVARAFFGPASASLFANLVPPEDFANAIAWNSSAWQTATIVGPVAGGLLYGVSPEVAYGT 181 Query: 188 SCVLFTLCSLLLSLIRRPACGQADRGQPVL 217 + VL LL+ I +PA + + +P L Sbjct: 182 AAVLMLASGLLIFTIPKPA-QRTETEKPTL 210 >BMEI0181 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 412 Score = 131 bits (330), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 75/195 (38%), Positives = 110/195 (56%) Query: 11 DASPEPPPPLRHHTPFKLFWCASVASTIALQMQIVAVGWQVYQLTHSAMDLGIVGLVQFI 70 DAS H+ FK +W A S A+Q+ V+VGWQ+Y LT A +LG+VGLVQF+ Sbjct: 5 DASSVDRFAAFRHSAFKKYWGARFLSAFAVQIVSVSVGWQIYDLTRDAFNLGMVGLVQFL 64 Query: 71 PSLILVFVVGHVADRFDRRNVARVSALVEALAAATLAAGSLGGWLNREIIFVIVAVIGAG 130 P+L+LV V G ADRF RR + +S ++E + A L A +L G +F + + G Sbjct: 65 PALLLVLVTGAAADRFGRRLIMGLSLILEGIVTAALLAFTLAGLFEPLTVFAALLIFGVA 124 Query: 131 RAFSKPTMSALLPSLMSPRQLPGAVAGSASATQFAIIIGPALGGFLYVAGPAVVYASSCV 190 RAF P+ ++L+ +L+ AV+ ++SA Q A I+GP GG LY P Y+ + + Sbjct: 125 RAFLGPSSASLVVNLVPTEDFANAVSWNSSAWQVATIVGPVAGGLLYGISPVAAYSIATL 184 Query: 191 LFTLCSLLLSLIRRP 205 SLL+ I +P Sbjct: 185 FLIAGSLLIFSIPKP 199 >SMc03237 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 415 Score = 128 bits (321), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 69/184 (37%), Positives = 109/184 (59%) Query: 23 HTPFKLFWCASVASTIALQMQIVAVGWQVYQLTHSAMDLGIVGLVQFIPSLILVFVVGHV 82 H ++ ++ + + + A+Q+ VAVGWQ+Y LT LG++GL QF+PSL+L+ V G V Sbjct: 15 HVGYRRYFFSRLLAYFAVQIMSVAVGWQIYDLTRDPFSLGLIGLFQFLPSLVLILVTGSV 74 Query: 83 ADRFDRRNVARVSALVEALAAATLAAGSLGGWLNREIIFVIVAVIGAGRAFSKPTMSALL 142 ADR++RR + + LV L A L ++ G + ++ I+ V G RAF P +L Sbjct: 75 ADRYNRRAIMGICMLVSTLCGAALLLLTVTGLFSPWPVYAILVVFGIERAFLGPASQSLA 134 Query: 143 PSLMSPRQLPGAVAGSASATQFAIIIGPALGGFLYVAGPAVVYASSCVLFTLCSLLLSLI 202 P+L+ LP A+A ++++ Q A+I+GP GG LY GP V YA S F +L++ + Sbjct: 135 PNLVPAEDLPNAIAWNSTSWQTAMIVGPVAGGLLYGFGPTVPYAVSLGFFAAGALMVFAV 194 Query: 203 RRPA 206 +PA Sbjct: 195 PKPA 198 >AGc4819 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 478 Score = 122 bits (306), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 68/166 (40%), Positives = 103/166 (62%) Query: 40 LQMQIVAVGWQVYQLTHSAMDLGIVGLVQFIPSLILVFVVGHVADRFDRRNVARVSALVE 99 +Q+ V+VGWQ+Y++T +A LG++GL QF+PSL+L+ V G VADR +RR + + L+ Sbjct: 100 IQIVSVSVGWQMYEVTGNAFYLGLIGLFQFLPSLLLILVTGTVADRHNRRRIMAICLLMA 159 Query: 100 ALAAATLAAGSLGGWLNREIIFVIVAVIGAGRAFSKPTMSALLPSLMSPRQLPGAVAGSA 159 AL A L +L + +F I+ V G RAF P + +L P+L+ LP A+A ++ Sbjct: 160 ALCAVALLGLTLTQSFSPWPVFAILVVFGIERAFMGPAVQSLAPNLVPVEDLPNAIAWNS 219 Query: 160 SATQFAIIIGPALGGFLYVAGPAVVYASSCVLFTLCSLLLSLIRRP 205 S+ Q A I+GP GG LY G +V Y+ + VLF + + L IR+P Sbjct: 220 SSWQMASILGPVAGGLLYGLGASVAYSVAFVLFIVSATLAVAIRKP 265 >all0371 [GEPR] COG0477 Permeases of the major facilitator superfamily Nos Nostoc sp. PCC 7120 Length = 422 Score = 99.0 bits (245), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 74/205 (36%), Positives = 107/205 (52%), Gaps = 17/205 (8%) Query: 13 SPEPPPPLRHHTPF--------KLFWCASVASTIALQMQIVAVGWQVYQLTHSAMDLGIV 64 SP P H PF +LF V ++ QMQ VA+GW++Y+ T+SAM LG V Sbjct: 8 SPPPSAEANQHDPFAALRFRDYRLFTLGRVLLSVGSQMQTVAIGWELYERTNSAMVLGGV 67 Query: 65 GLVQFIPSLILVFVVGHVADRFDRRNVARVSALVEALAAATLAAGSLGGWLNREIIFVI- 123 GL Q +P + L V G +ADR R+ +S ++ AL + LA S R +F+I Sbjct: 68 GLAQVLPMIALTLVAGDIADRRSRKLTILLSVMLLALCSLGLAVLS----YTRGAVFLIY 123 Query: 124 --VAVIGAGRAFSKPTMSALLPSLMSPRQLPGAVAGSASATQFAIIIGPALGGF-LYVAG 180 +A+IG GRAF KP A++ L+ A ++S+ Q A + GPALGG + V G Sbjct: 124 GCLALIGVGRAFLKPASDAIMWQLIPVNVFTNAATWNSSSFQLASVAGPALGGLGIAVLG 183 Query: 181 PAV-VYASSCVLFTLCSLLLSLIRR 204 A VY + + LC L ++ I+ Sbjct: 184 SATGVYILAAIAGFLCFLFMAAIKE 208 >CC0403 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 429 Score = 89.0 bits (219), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 60/170 (35%), Positives = 86/170 (50%), Gaps = 7/170 (4%) Query: 1 MSSTHADAAADASPEPPPPLRHHTPFKLFWCASVASTIALQMQIVAVGWQVYQLT----- 55 MS T A + A P L F LFW A ST+ +Q+Q VA+GWQVY + Sbjct: 8 MSDTAAPPSEPALENPTRALLRERDFLLFWAARFVSTLGVQIQSVALGWQVYAIARMTKS 67 Query: 56 --HSAMDLGIVGLVQFIPSLILVFVVGHVADRFDRRNVARVSALVEALAAATLAAGSLGG 113 SA + ++GL QF+P +L V G ADR R+ + + ++A++A L +L G Sbjct: 68 VGESAFLVSMIGLAQFLPLFLLTLVAGETADRRTRKLIVAATLALDAISAGVLLVLALMG 127 Query: 114 WLNREIIFVIVAVIGAGRAFSKPTMSALLPSLMSPRQLPGAVAGSASATQ 163 IF I + GA RAF P SA+ P L+ LP A+A ++ + Q Sbjct: 128 SHQLWPIFAISVLFGASRAFLSPASSAMGPMLVPRPLLPRAIAWNSLSWQ 177 >PA2701 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 529 Score = 74.7 bits (182), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 63/201 (31%), Positives = 98/201 (48%), Gaps = 5/201 (2%) Query: 16 PPPPLRHHTPFKLFWCASVASTIALQMQIVAVGWQVYQLTHSAMDLGIVGLVQFIPSLIL 75 P PLR T F+ W AS+AS I M V GW + L+ S +++ +V + +P L Sbjct: 8 PWSPLRQTT-FRWLWLASIASNIGTWMHEVGAGWLMTSLSASPLNVALVQVAGSLPMFFL 66 Query: 76 VFVVGHVADRFDRRNVARVSALVEALAAATLAAGSLGGWLNREIIFVIVAVIGAGRAFSK 135 G +AD D+R L AL A LA+ +L + ++ + +G G A Sbjct: 67 ALPAGALADIVDKRRYLLGVQLWMALVATLLASLTLLQLTSVWLLLGLTLCMGIGTALMM 126 Query: 136 PTMSALLPSLMSPRQLPGAVAGSASATQFAIIIGPALGGFLY-VAGPAVVYASSCV-LFT 193 P SA P L+ +LP AVA S+ A +GPA+ G L + GP + +A + + F Sbjct: 127 PAWSATTPELVGKDELPAAVALSSVGVNLARAVGPAIAGVLVSLVGPWLTFALNALSFFA 186 Query: 194 LCSLLLSLIRR--PACGQADR 212 + ++LL+ R P+ A+R Sbjct: 187 VIAVLLAWKREAVPSVLPAER 207