BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0049.p (144 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr7896 [GER] COG0697 Permeases of the drug/metabolite transport... 107 1e-23 mll3062 [GER] COG0697 Permeases of the drug/metabolite transport... 99 3e-21 BMEI1244 [GER] COG0697 Permeases of the drug/metabolite transpor... 98 6e-21 SMc01807 [GER] COG0697 Permeases of the drug/metabolite transpor... 91 1e-18 PA0539 [GER] COG0697 Permeases of the drug/metabolite transporte... 87 1e-17 STM3796A [GER] COG0697 Permeases of the drug/metabolite transpor... 86 2e-17 AGc2304 [GER] COG0697 Permeases of the drug/metabolite transport... 62 5e-10 >mlr7896 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 278 Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 55/112 (49%), Positives = 75/112 (66%) Query: 1 MNIAVIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWF 60 M+ VI L L AA+LHASWNA L++ DRL ++ +M+ AIPL ++ +P ++W Sbjct: 1 MSPLVIGLALFAAILHASWNAFLRTGADRLWTVTVMSFSDTALAIPLAIFNGFPATSAWP 60 Query: 61 YIILSGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQL 112 Y+ LS L GY++FL+ AYR G+ GQ YPI RGS PLLV LG + AG+QL Sbjct: 61 YVGLSACLQVGYSVFLVAAYRYGELGQVYPIVRGSVPLLVTLGGFLLAGQQL 112 >mll3062 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 281 Score = 99.0 bits (245), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 51/113 (45%), Positives = 73/113 (64%) Query: 19 WNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWFYIILSGLLHTGYNLFLIR 78 WNAL+K DR S+ LMTLG G A+ ++ + +P+ W +I+ S + H GY FLI Sbjct: 19 WNALVKVHLDRFLSITLMTLGMGFAALFVLPFVEFPKAEVWPFILASVVFHMGYRTFLIG 78 Query: 79 AYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGILLVSLGIVSLA 131 AYR GDF Q+YP+ARG++PLL ALG V E + ++GILL+S G + ++ Sbjct: 79 AYRAGDFAQTYPLARGTAPLLAALGGIVVVQEVPAPFAILGILLLSAGTLVMS 131 >BMEI1244 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bme Brucella melitensis Length = 281 Score = 97.8 bits (242), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 57/140 (40%), Positives = 86/140 (61%), Gaps = 1/140 (0%) Query: 1 MNIAVIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWF 60 M+ V+ +VL A LH SWNA++K S D+ A +T AG+ A+ L+ + P P ASW Sbjct: 1 MSGGVLLIVLFGAFLHTSWNAIVKGSGDKFFGAASVTGAAGLIALFLVPFLPLPTAASWI 60 Query: 61 YIILSGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGI 120 Y++LS + T Y + AY+ GD ++YPI RG+ PLLVAL + GE +G + +GI Sbjct: 61 YMLLSTITQTFYMSLVAAAYKSGDMSEAYPIMRGTPPLLVALVSGPLVGEIMGWQSWLGI 120 Query: 121 LLVSLGIVSLA-DLRAMRRG 139 +L+ G++++A D R RG Sbjct: 121 VLICSGVLAMALDARRRNRG 140 >SMc01807 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 278 Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 51/127 (40%), Positives = 80/127 (62%) Query: 5 VIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWFYIIL 64 VIALVL ALLHA+WNAL+K+ ++ A+++LG + A+P + + P P + YI++ Sbjct: 5 VIALVLLGALLHATWNALVKAGTEKSLDAAMVSLGGAVVALPFLPFLPMPGSEAVPYILV 64 Query: 65 SGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGILLVS 124 S L Y + AYR GD G YP+ RG +PL+VA +++ GE+L + GI+ +S Sbjct: 65 SALFQFAYFQLVAAAYRAGDIGLVYPLMRGVAPLIVAATSSLVIGEKLTGGAMAGIMTIS 124 Query: 125 LGIVSLA 131 G+++LA Sbjct: 125 AGVLTLA 131 >PA0539 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 276 Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 51/124 (41%), Positives = 75/124 (60%) Query: 7 ALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWFYIILSG 66 +LVL AA+LHA+WN L+K S DRL +A M + + AI L+ + P W +++ + Sbjct: 5 SLVLCAAVLHATWNTLVKFSSDRLLVVACMDVVGVLCAILLLPFVSLPPAEVWPWLLGAT 64 Query: 67 LLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGILLVSLG 126 +L Y + LI AY++GD G YP+ RG SPL+V F GEQL ++GILL+ G Sbjct: 65 VLQLLYRVLLIEAYKVGDLGLVYPLMRGLSPLVVLGLTLAFGGEQLSGRQILGILLIPFG 124 Query: 127 IVSL 130 ++ L Sbjct: 125 MLCL 128 >STM3796A [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sty Salmonella typhimurium LT2 Length = 286 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 46/131 (35%), Positives = 82/131 (62%) Query: 1 MNIAVIALVLAAALLHASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWF 60 M ++V ++L AALLHASWNA++K+ +D+L + ++ A + A+ L+ + P P AS Sbjct: 10 MTLSVFCILLFAALLHASWNAIVKAGNDKLYAAIGVSGSAAVMALILLPFSPQPAHASIP 69 Query: 61 YIILSGLLHTGYNLFLIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGI 120 ++ S L Y + + + Y++ D Q+YP+ RG++PLLVAL + +F G+ L +GI Sbjct: 70 FLAASTALQVVYTVLVAKTYQVSDMSQTYPLMRGTAPLLVALISVLFLGDSLSSLAWVGI 129 Query: 121 LLVSLGIVSLA 131 ++ + I+ +A Sbjct: 130 AVICMAILGMA 140 >AGc2304 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 305 Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 47/124 (37%), Positives = 72/124 (58%), Gaps = 2/124 (1%) Query: 16 HASWNALLKSSHDRLASLALMTLGAGIGAIPLILWRPWPEPASWFYIILSGLLHTGYNLF 75 HA WNAL+KS D+ +L+ GA ++P + + P+P P + ++I S +L Y Sbjct: 43 HAGWNALVKSGSDKSLDASLIAAGAAACSLPFLPFLPFPAPVAIPFLIASAVLQFAYFRL 102 Query: 76 LIRAYRIGDFGQSYPIARGSSPLLVALGAAVFAGEQLGLYTVIGILLVSLGIVSLADLRA 135 + AY IGD G YP+ RG +PL+VA +++F E L + GI ++S GI++LA Sbjct: 103 VAAAYTIGDIGLVYPVMRGVAPLIVAATSSLFLSEVLSPLALAGIAVISGGILTLAF--E 160 Query: 136 MRRG 139 RRG Sbjct: 161 ARRG 164