BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0035.p (409 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CC3635 [E] COG1171 Threonine dehydratase Ccr Caulobacter vibrioides 365 e-101 TM0356 [E] COG1171 Threonine dehydratase Tma Thermotoga maritima 293 6e-79 VNG2100G [E] COG1171 Threonine dehydratase Hbs Halobacterium sp.... 274 3e-73 Cj0828c [E] COG1171 Threonine dehydratase Cje Campylobacter jejuni 273 4e-73 Ta0113 [E] COG1171 Threonine dehydratase Tac Thermoplasma acidop... 266 7e-71 TVN0190 [E] COG1171 Threonine dehydratase Tvo Thermoplasma volca... 265 1e-70 FN1411 [E] COG1171 Threonine dehydratase Fnu Fusobacterium nucle... 265 1e-70 SA1271 [E] COG1171 Threonine dehydratase Sau Staphylococcus aure... 219 1e-56 PA0331 [E] COG1171 Threonine dehydratase Pae Pseudomonas aeruginosa 211 4e-54 SSO0248 [E] COG1171 Threonine dehydratase Sso Sulfolobus solfata... 208 2e-53 >CC3635 [E] COG1171 Threonine dehydratase Ccr Caulobacter vibrioides Length = 400 Score = 365 bits (938), Expect = e-101, Method: Compositional matrix adjust. Identities = 198/392 (50%), Positives = 281/392 (71%), Gaps = 1/392 (0%) Query: 12 LNDIEAAARRLQGQILETPCVESRTLSQIVGAQVFLKFENLQFTASFKERGACNKLVDVA 71 L I+AAA RLQGQI TPC S+TLS+I GA+V++KFENLQFTA++KERGA NKL+ ++ Sbjct: 5 LAAIQAAAGRLQGQIERTPCRHSKTLSKITGAEVWVKFENLQFTAAYKERGALNKLMLLS 64 Query: 72 ASGGGARGVVAMSAGNHAQGVAYHAQRLGLPATIVMPRFTPGVKIERTRGFGANVVLHGD 131 + RGV+A SAGNHAQG+AYH RLG+P TIVMP+ TP VK++ TR FGA VV+ G+ Sbjct: 65 ETEK-QRGVIAASAGNHAQGLAYHGARLGVPVTIVMPKTTPFVKVQHTRDFGATVVIEGE 123 Query: 132 TLEAARTHAYELAEKEGLTFVHPYDDEAIIAGQGTVALEMMKAVPDLDCLVVSIGGGGLL 191 T + A HA +L +++GLTFVHP+DD I+AGQGT+ALEM++ PDL+ L V IGGGGL+ Sbjct: 124 TYDDANAHARKLRDEQGLTFVHPFDDYDIMAGQGTIALEMLEDAPDLEILPVPIGGGGLI 183 Query: 192 AGMAVAARAIKPEIEIVGVQTRRFPTMVNAVKGTEHPVGASTIAEGIAVGTPGTLTRAII 251 +G+A AA+A+KP+I I+G + +P+ ++G G TIAEG+AV G LT ++ Sbjct: 184 SGVATAAKALKPDIRIIGCEPAMYPSFTAKMRGVAAHCGGQTIAEGVAVKQVGELTYGVV 243 Query: 252 AREADELLLVDEGDIEQAVLMLLEIEKTLVEGAGAAGLAALVRYPDRFRGKRVGLVLSGG 311 D++LL++E +EQAV + +EKT+ EGAGAA LAAL+ YP+RFRGK+ GL+L GG Sbjct: 244 RPLLDDVLLLEEPYLEQAVSLYCNVEKTIAEGAGAASLAALLAYPERFRGKKCGLILCGG 303 Query: 312 NIDPLLLTAIIERGMVRAGRLARVKVSSRDVPGTLARITGIVAEAGANVDEVHHQRAFTL 371 NID LL +++ R +VRA RLA +++ D PG L+ + ++ GAN+ EV+H R Sbjct: 304 NIDTRLLASVLTRELVRAQRLASLRIIGDDRPGLLSTVASVIGAMGANIIEVNHNRLALD 363 Query: 372 LAAQNVDIELVLQTRGRPHLAQVLQALRAAGF 403 + A+ + ++ ++TR H +V++ALR +G+ Sbjct: 364 VPAKGAEFDITIETRDAQHTQEVMEALRESGY 395 >TM0356 [E] COG1171 Threonine dehydratase Tma Thermotoga maritima Length = 401 Score = 293 bits (749), Expect = 6e-79, Method: Compositional matrix adjust. Identities = 177/398 (44%), Positives = 257/398 (64%), Gaps = 4/398 (1%) Query: 9 MTTLNDIEAAARRLQGQILETPCVESRTLSQIVGAQVFLKFENLQFTASFKERGACNKLV 68 M TL DI+ A R L+ + T S LS++ G +++LK ENLQ T SFK RGA NK+ Sbjct: 1 MITLEDIKEAQRTLKNVVHRTALAYSSVLSEVTGGEIYLKMENLQKTGSFKIRGAYNKIA 60 Query: 69 DVAASGGGARGVVAMSAGNHAQGVAYHAQRLGLPATIVMPRFTPGVKIERTRGFGANVVL 128 ++ RGVVA SAGNHAQGVA AQ G+PATIVMPR+ P KI +TR GA V+L Sbjct: 61 HLSEEER-KRGVVAASAGNHAQGVALAAQIFGIPATIVMPRYAPLSKITKTRNLGAQVIL 119 Query: 129 HGDTLEAARTHAYELAEKEGLTFVHPYDDEAIIAGQGTVALEMMKAVPDLDCLVVSIGGG 188 G+ + A A + EK G FVHP++D +IAGQGT+ LE+M+ +PD++ +VV +GGG Sbjct: 120 EGNIFDEAYEAALRIQEKTGAVFVHPFNDPHVIAGQGTIGLEIMEDLPDVEVVVVPVGGG 179 Query: 189 GLLAGMAVAARAIKPEIEIVGVQTRRFPTMVNAVK--GTEHPVGASTIAEGIAVGTPGTL 246 GL++G++VA +++ PE++++GVQT P+M+ +++ E G T+A+GIAV PG L Sbjct: 180 GLISGVSVAIKSMNPEVKVIGVQTENMPSMIASLRRGRAERVEGKPTLADGIAVKKPGDL 239 Query: 247 TRAIIAREADELLLVDEGDIEQAVLMLLEIEKTLVEGAGAAGLAALVRYPDRFRGKRVGL 306 T ++ + DE++ V+E +I A+L LLE K + EGAGA G+AA++ D +GK+V + Sbjct: 240 TFELVKKYVDEMVAVNEEEIADAILFLLEQAKVVAEGAGAVGVAAVLNKLD-VKGKKVAI 298 Query: 307 VLSGGNIDPLLLTAIIERGMVRAGRLARVKVSSRDVPGTLARITGIVAEAGANVDEVHHQ 366 V+SGGNID ++ II +G+V++GR ++ D PG L + GIVAE GANV V H Sbjct: 299 VISGGNIDVNMIDRIINKGLVKSGRKVFIETFVMDRPGALKELLGIVAELGANVLSVFHN 358 Query: 367 RAFTLLAAQNVDIELVLQTRGRPHLAQVLQALRAAGFE 404 R+ + IEL L+T H+ ++ + L A G+E Sbjct: 359 RSAKEVPIGFAKIELELETVDEKHVEEIERVLIAKGYE 396 >VNG2100G [E] COG1171 Threonine dehydratase Hbs Halobacterium sp. NRC-1 Length = 495 Score = 274 bits (700), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 168/407 (41%), Positives = 239/407 (58%), Gaps = 8/407 (1%) Query: 8 NMTTLNDIEAAARRLQGQILETPCVESRTLSQIVGAQVFLKFENLQFTASFKERGACNKL 67 +M +L+DI A R+ TP S T S + GA V K E Q T SFK RGA N++ Sbjct: 85 SMLSLSDIRDARERVSETARHTPLEYSHTFSDLTGADVRPKLECFQRTGSFKIRGATNRI 144 Query: 68 VDVAASGGGARGVVAMSAGNHAQGVAYHAQRLGLPATIVMPRFTPGVKIERTRGFGANVV 127 ++A A GVV SAGNHAQGVA A R G+ + +VMP P KI+ T+ +GA VV Sbjct: 145 RTLSADQQDA-GVVTASAGNHAQGVALAASRSGVDSKVVMPESAPISKIKATKSYGAEVV 203 Query: 128 LHGDTLEAARTHAYELAEKEGLTFVHPYDDEAIIAGQGTVALEMMKAVPDLDCLVVSIGG 187 LHG + A+ HA+EL EG T+VH +DDE I+AGQGT+ LE+ P +D +VV IGG Sbjct: 204 LHGADYDDAQAHAHELEAAEGRTYVHAFDDEYIMAGQGTLGLEIAADCPTVDTVVVPIGG 263 Query: 188 GGLLAGMAVAARAIKPEIEIVGVQTRRFPTMVNAV-KGTEHPVG-ASTIAEGIAVGTPGT 245 GGL++G+A A + ++ ++GVQ T+ ++ KG V TIA+GIAV G Sbjct: 264 GGLISGVATALKGELDDVRVIGVQAEGASTVARSLDKGQPQAVDHVDTIADGIAVRQVGA 323 Query: 246 LTRAIIAREADELLLVDEGDIEQAVLMLLEIEKTLVEGAGAAGLAALVRYPDRFR---GK 302 T +I DE++ V + +I A+++LLE KTLVEGAGA LAA++ D+F G+ Sbjct: 324 QTFPVIQEHVDEVVTVSDDEIATALVLLLERGKTLVEGAGATALAAVLE--DKFEYADGE 381 Query: 303 RVGLVLSGGNIDPLLLTAIIERGMVRAGRLARVKVSSRDVPGTLARITGIVAEAGANVDE 362 + L GGNID LLT +I RG+V GR +++ +D PG+L + AE AN+ Sbjct: 382 TIVPALCGGNIDLNLLTTVIVRGLVDQGRYVKIRTVLKDSPGSLNDLLATAAEERANIYA 441 Query: 363 VHHQRAFTLLAAQNVDIELVLQTRGRPHLAQVLQALRAAGFEAEELH 409 + H R +A ++EL L+TRG H+ ++L ++ GF+ L+ Sbjct: 442 IQHDRTNRDIAMNATEVELDLETRGPEHVDRLLTRIQDEGFDVTVLN 488 >Cj0828c [E] COG1171 Threonine dehydratase Cje Campylobacter jejuni Length = 403 Score = 273 bits (699), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 156/402 (38%), Positives = 242/402 (60%), Gaps = 4/402 (0%) Query: 9 MTTLNDIEAAARRLQGQILETPCVESRTLSQIVGAQVFLKFENLQFTASFKERGACNKLV 68 M LN I A +++ G + +TP + S LS I ++++LK ENLQ T ++K RGA NK+ Sbjct: 1 MLELNKIYKAKQQISGFVNKTPFIYSSFLSDICQSEIYLKNENLQITGAYKIRGAYNKIA 60 Query: 69 DVAASGGGARGVVAMSAGNHAQGVAYHAQRLGLPATIVMPRFTPGVKIERTRGFGANVVL 128 +++ + GV+A SAGNHAQGVA A++ + A IVMP TP +K+ T+ GA V+L Sbjct: 61 NLS-TEQKQHGVIAASAGNHAQGVAISAKKFSIKAVIVMPESTPLLKVSATKALGAEVIL 119 Query: 129 HGDTLEAARTHAYELAEKEGLTFVHPYDDEAIIAGQGTVALEMMKAVPDLDCLVVSIGGG 188 GD + A A A++ L+F+HP++DE ++AGQGT+ LEM+ + DLD ++ +GGG Sbjct: 120 RGDNFDEAYAFATSYAKENNLSFIHPFEDEFVMAGQGTLMLEMLDEISDLDMIIAPVGGG 179 Query: 189 GLLAGMAVAARAIKPEIEIVGVQTRRFPTMVNAV--KGTEHPVGASTIAEGIAVGTPGTL 246 GL++G++ A+ I P I+I+GV + P M + K ++ TIA+GIAV + Sbjct: 180 GLISGISSTAKQINPNIKIIGVGAKGAPAMYESFHAKKIKNAKSVRTIADGIAVRDANPI 239 Query: 247 TRAIIAREADELLLVDEGDIEQAVLMLLEIEKTLVEGAGAAGLAALVRYPDRFRG-KRVG 305 II D+ + VD+ +I AVL LLE K +VEGAGAA +AAL+ + K++G Sbjct: 240 NFNIILECVDDFIQVDDEEIANAVLFLLEKHKIIVEGAGAASVAALLHQKINTQNHKKIG 299 Query: 306 LVLSGGNIDPLLLTAIIERGMVRAGRLARVKVSSRDVPGTLARITGIVAEAGANVDEVHH 365 +VLSGGNID +L IIE+G+ ++ R ++ V+ D PG L +T + A AN+ ++ + Sbjct: 300 VVLSGGNIDAQMLNIIIEKGLFKSYRKMQIYVTLVDKPGALLHLTDSLKIANANIVKIDY 359 Query: 366 QRAFTLLAAQNVDIELVLQTRGRPHLAQVLQALRAAGFEAEE 407 R T L + I + L+T+G+ H ++ + L F E Sbjct: 360 DRFSTKLDYGDAMISITLETKGKEHQEEIRKILTQKAFNFYE 401 >Ta0113 [E] COG1171 Threonine dehydratase Tac Thermoplasma acidophilum Length = 406 Score = 266 bits (680), Expect = 7e-71, Method: Compositional matrix adjust. Identities = 152/400 (38%), Positives = 235/400 (58%), Gaps = 9/400 (2%) Query: 9 MTTLNDIEAAARRLQGQILETPCVESRTLSQIVGAQVFLKFENLQFTASFKERGACNKLV 68 + + DI +A L+G+I TP ++S T G++++ K EN Q T SFK RGA K Sbjct: 6 IPSYEDILSAKAYLEGRINRTPLIKSTTFGNEYGSEMYFKLENFQKTGSFKSRGALFKFS 65 Query: 69 DVAASGGGARGVVAMSAGNHAQGVAYHAQRLGLPATIVMPRFTPGVKIERTRGFGANVVL 128 ++ RGV+ SAGNHAQGVAY A+ G+ A IVMP +T K+ G+GA V+L Sbjct: 66 KLSEDDR-RRGVLTASAGNHAQGVAYAAKVNGINAKIVMPEYTIPQKVNAVAGYGAEVIL 124 Query: 129 HGDTLEAARTHAYELAEKEGLTFVHPYDDEAIIAGQGTVALEMMKAVPDLDCLVVSIGGG 188 HG + A +A +LA KE F+ ++D +I+GQGT+ LE+M+ PD+D ++V +GGG Sbjct: 125 HGFDYDEAHRYADDLARKENRVFIEAFNDRWVISGQGTIGLEIMEDRPDIDTIIVPVGGG 184 Query: 189 GLLAGMAVAARAIKPEIEIVGVQTRRFPTMVNAV---KGTEHPVGASTIAEGIAVGTPGT 245 GL++G+A+AA+ P + I+G+++ +M ++ K H G S I +GI+V PG Sbjct: 185 GLISGIALAAKHHNPHVRIIGIESELSDSMKASLREGKIVAHTSGVS-ICDGISVKYPGD 243 Query: 246 LTRAIIAREADELLLVDEGDIEQAVLMLLEIEKTLVEGAGAAGLAALVRYPDRFRGKRVG 305 LT I D+++ V E + +A+ L E K + E +GA GLAA++ +G++V Sbjct: 244 LTFNIAKDYVDDIVTVTEESVSKAIYRLFERMKIVAEPSGAVGLAAIMEGKVDVKGRKVA 303 Query: 306 LVLSGGNIDPLLLTAIIERGMVRAGRLARVKVSSRDVPGTLARITGIVAEAGANVD--EV 363 +V+SGGNI+PLL++ II + + G+L R++ D PG L RI +A+ G N+ EV Sbjct: 304 IVVSGGNINPLLMSKIIYKELENLGQLVRIECIIPDRPGNLYRIAEAIAKNGGNIYHAEV 363 Query: 364 HHQRAFTLLAAQNVDIELVLQTRGRPHLAQVLQALRAAGF 403 + R T Q+V + RG+ HL ++L LR G+ Sbjct: 364 DNLRKETPPGFQSVIFS--VNVRGQDHLDRILSTLREMGY 401 >TVN0190 [E] COG1171 Threonine dehydratase Tvo Thermoplasma volcanium Length = 406 Score = 265 bits (678), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 148/403 (36%), Positives = 241/403 (59%), Gaps = 9/403 (2%) Query: 6 NRNMTTLNDIEAAARRLQGQILETPCVESRTLSQIVGAQVFLKFENLQFTASFKERGACN 65 N + + ++I A R L+G++ TP + S T+ + GA ++ K EN Q T SFK RGA Sbjct: 3 NLEIPSFDEIIEAQRYLEGKVNRTPLIRSTTIGKEYGADIYFKLENFQKTGSFKSRGAIF 62 Query: 66 KLVDVAASGGGARGVVAMSAGNHAQGVAYHAQRLGLPATIVMPRFTPGVKIERTRGFGAN 125 + ++ GV+ SAGNHAQGVAY A G+ A IVMP +T K+ +GA+ Sbjct: 63 RFSKLSEDEK-RHGVITASAGNHAQGVAYAAMINGIDAKIVMPEYTIPQKVNAVISYGAH 121 Query: 126 VVLHGDTLEAARTHAYELAEKEGLTFVHPYDDEAIIAGQGTVALEMMKAVPDLDCLVVSI 185 V+L G + A +A E+A++EG F+ ++D +I+GQGT+ LE+M+ +PD+D ++V + Sbjct: 122 VILKGSDYDEAHRYADEIAKQEGRIFIEAFNDRWVISGQGTIGLEIMEDLPDVDIILVPV 181 Query: 186 GGGGLLAGMAVAARAIKPEIEIVGVQTRRFPTMVNAV---KGTEHPVGASTIAEGIAVGT 242 GGGGL++G+A+AA+ +++++G+++ +M ++ K H G S I +GI+V Sbjct: 182 GGGGLISGIALAAKHASNKVKVIGIESELSDSMKASLREGKIVAHTSGVS-ICDGISVKY 240 Query: 243 PGTLTRAIIAREADELLLVDEGDIEQAVLMLLEIEKTLVEGAGAAGLAALVRYPDRFRGK 302 PG LT I + D+++ V E + +A+ L E K + E +GA GLAA++ +GK Sbjct: 241 PGVLTFDIARKYVDDIVTVTEEYVSKAIYKLFERNKIVAEPSGAVGLAAIMEGKVDVKGK 300 Query: 303 RVGLVLSGGNIDPLLLTAIIERGMVRAGRLARVKVSSRDVPGTLARITGIVAEAGANVD- 361 +V +V+SGGNI+PLL++ II + + G+L R++ + D PG L RI +AE G N+ Sbjct: 301 KVAIVVSGGNINPLLMSKIIYKELENLGQLVRIECTIPDRPGNLYRIAMAIAENGGNIYH 360 Query: 362 -EVHHQRAFTLLAAQNVDIELVLQTRGRPHLAQVLQALRAAGF 403 EV + R T Q+V + RG+ HL +++ +LR G+ Sbjct: 361 AEVDNLRKETPPGFQSV--TFTVNVRGQDHLDRIIGSLREMGY 401 >FN1411 [E] COG1171 Threonine dehydratase Fnu Fusobacterium nucleatum Length = 404 Score = 265 bits (677), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 163/400 (40%), Positives = 252/400 (63%), Gaps = 9/400 (2%) Query: 9 MTTLNDIEAAARRLQGQILETPCVESRTLSQIVGAQVFLKFENLQFTASFKERGACNKLV 68 M L A +L +LET + S S+ G +VF+K ENLQ T SFK RGA NK+ Sbjct: 1 MAKLEAFIKAKEKLSKVLLETQLIYSPIFSKESGNKVFIKPENLQKTGSFKIRGAYNKIS 60 Query: 69 DVAASGGGARGVVAMSAGNHAQGVAYHAQRLGLPATIVMPRFTPGVKIERTRGFGANVVL 128 ++ RGV+A SAGNHAQGVAY A+ G+ A IVMP+ TP +K+E T+ +GA V+L Sbjct: 61 NLT-DAEKKRGVIASSAGNHAQGVAYGAKESGIKAVIVMPKSTPLIKVESTKQYGAEVIL 119 Query: 129 HGDTLEAARTHAYELAEKEGLTFVHPYDDEAIIAGQGTVALEMMKAVPDLDCLVVSIGGG 188 HGD + A A EL EKEG FVHP++DE ++ GQGT+ALE+++ +P+ D ++V IGGG Sbjct: 120 HGDVYDDAFKKAKELEEKEGYVFVHPFNDEDVLDGQGTIALEILEELPETDIILVPIGGG 179 Query: 189 GLLAGMAVAARAIKPEIEIVGVQTRRFPTMVNAVKGTEHPV----GASTIAEGIAVGTPG 244 GL++G+A AA+ +KPEI+I+GV+ + A+K E+ V A+TIA+G AV G Sbjct: 180 GLISGIACAAKILKPEIKIIGVEPEGAASAYEAIK--ENKVVELKEANTIADGTAVKKIG 237 Query: 245 TLTRAIIAREADELLLVDEGDIEQAVLMLLEIEKTLVEGAGAAGLAALVRYPDRFRGKRV 304 L I + DE++ V + ++ +A L+L+E K + E +G +AA + + + K+V Sbjct: 238 DLNFEYIKKYVDEIITVSDYELMEAFLLLVEKHKIIAENSGILSIAATKK--LKEKNKKV 295 Query: 305 GLVLSGGNIDPLLLTAIIERGMVRAGRLARVKVSSRDVPGTLARITGIVAEAGANVDEVH 364 V+SGGNID L+++++I +G++R R+ VS D PG LA++ ++AE GANV ++ Sbjct: 296 VSVISGGNIDVLMISSMINKGLIRRDRIFNFTVSIPDKPGELAKVVDLIAEQGANVIKLE 355 Query: 365 HQRAFTLLAAQNVDIELVLQTRGRPHLAQVLQALRAAGFE 404 H + L +++++++ ++T G H+ + QA G+E Sbjct: 356 HNQFKNLSRFKDIELQITVETNGSEHVQNLTQAFEEKGYE 395 >SA1271 [E] COG1171 Threonine dehydratase Sau Staphylococcus aureus N315 Length = 346 Score = 219 bits (557), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 136/331 (41%), Positives = 198/331 (59%), Gaps = 9/331 (2%) Query: 3 SLYNRNMTTLNDIEAAARRLQGQILETPCVESRTLSQ-IVGAQVFLKFENLQFTASFKER 61 +L ++ +L DIE A ++ I TP ++S LSQ I V+LK EN+QFT SFK R Sbjct: 7 TLQTAHIVSLGDIEEAKASIKPFIRRTPLIKSMYLSQNITKGNVYLKLENMQFTGSFKFR 66 Query: 62 GACNKLVDVAASGGGARGVVAMSAGNHAQGVAYHAQRLGLPATIVMPRFTPGVKIERTRG 121 GA NK ++ + A+G++ SAGNHAQGVA A+ LG+ ATIVMP P K T+G Sbjct: 67 GASNK-INHLSDEQKAKGIIGASAGNHAQGVALTAKLLGIDATIVMPETAPIAKQNATKG 125 Query: 122 FGANVVLHGDTLEAARTHAYELAEKEGLTFVHPYDDEAIIAGQGTVALEMMKAVPDLDCL 181 +GA V+L G R + ELA++ G+T VHPYDD+ ++AGQGT+ LE++ + +++ + Sbjct: 126 YGAKVILKGKNFNETRLYMEELAKENGMTIVHPYDDKFVMAGQGTIGLEILDDIWNVNTV 185 Query: 182 VVSIGGGGLLAGMAVAARAIKPEIEIVGVQTRRFPTMVNAVKG---TEHPVGASTIAEGI 238 +V +GGGGL+AG+A A ++ P I I+GVQ M + TEH STIA+G Sbjct: 186 IVPVGGGGLIAGIATALKSFNPSIHIIGVQAENVHGMAESFYKRALTEHRED-STIADGC 244 Query: 239 AVGTPGTLTRAIIAREADELLLVDEGDIEQAVLMLLEIEKTLVEGAGAAGLAALVR---Y 295 V PG T ++ DE +LV E +IE A+ L++ K + EGAGA AA++ Sbjct: 245 DVKVPGEKTYEVVKHLVDEFILVSEEEIEHAMQDLMQRAKIITEGAGALPTAAILSGKID 304 Query: 296 PDRFRGKRVGLVLSGGNIDPLLLTAIIERGM 326 GK V ++SGGN+D ++ +IE G+ Sbjct: 305 KKWLEGKNVVALVSGGNVDLTRVSGVIEHGL 335 >PA0331 [E] COG1171 Threonine dehydratase Pae Pseudomonas aeruginosa Length = 504 Score = 211 bits (536), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 129/325 (39%), Positives = 191/325 (58%), Gaps = 6/325 (1%) Query: 27 LETPCVESRTLSQIVGAQVFLKFENLQFTASFKERGACNKLVDVAASGGGARGVVAMSAG 86 +ETP +R LS+ +G QV LK E+LQ SFK RGA NK+ + ARGV+A SAG Sbjct: 19 VETPLQPARQLSERLGNQVLLKREDLQPVFSFKIRGAYNKVAQLTEEEK-ARGVIAASAG 77 Query: 87 NHAQGVAYHAQRLGLPATIVMPRFTPGVKIERTRGFGANVVLHGDTLEAARTHAYELAEK 146 NHAQG+A A+R G+ A IVMP+ TP +K++ R GA VLHGD A HA +L ++ Sbjct: 78 NHAQGLALAAKRQGIRAVIVMPKTTPEIKVQAVRAHGAKAVLHGDAFPEALAHALKLVDE 137 Query: 147 EGLTFVHPYDDEAIIAGQGTVALEMMKAVP-DLDCLVVSIGGGGLLAGMAVAARAIKPEI 205 +G TFVHPYDD IAGQGTVA+E+++ P LD + V +GGGGL+AG+A + ++PEI Sbjct: 138 KGYTFVHPYDDPDTIAGQGTVAMEILRQQPGRLDAIFVPVGGGGLVAGIAAYVKYLRPEI 197 Query: 206 EIVGVQTRRFPTMVNAVKGTEHPV--GASTIAEGIAVGTPGTLTRAIIAREADELLLVDE 263 +++GV+ + A+ E V A+G+AV G T I DE++ V Sbjct: 198 KVIGVEPDESNCLQAAMAAGERVVLGQVGLFADGVAVAQIGQHTFDICKDHVDEVITVST 257 Query: 264 GDIEQAVLMLLEIEKTLVEGAGAAGLAALVRYPDRFR--GKRVGLVLSGGNIDPLLLTAI 321 +I A+ + + +++ E AGA +A + +Y +R R G+ + + SG N++ L + Sbjct: 258 DEICAAIKDIYDDTRSITEPAGALAVAGIKKYVERERAEGQTLVAIDSGANVNFDRLRHV 317 Query: 322 IERGMVRAGRLARVKVSSRDVPGTL 346 ER + R A + V+ + PG+ Sbjct: 318 AERAELGERREAIIAVTIPERPGSF 342 >SSO0248 [E] COG1171 Threonine dehydratase Sso Sulfolobus solfataricus Length = 405 Score = 208 bits (530), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 146/357 (40%), Positives = 211/357 (59%), Gaps = 7/357 (1%) Query: 15 IEAAARRLQGQILETPCVESRTLSQIVGAQVFLKFENLQFTASFKERGACNKLVDVAASG 74 I A +++ + TP S T S+I+ A+V+LK ENLQ T SFK RGA NKL+ + Sbjct: 10 IRLAKEKIEKYVHITPIDYSTTFSRIINAKVYLKLENLQKTGSFKVRGAFNKLLSLKEEE 69 Query: 75 GGARGVVAMSAGNHAQGVAYHAQRLGLPATIVMPRFTPGVKIERTRGFGANVVLHGDTLE 134 GV+A+SAGNHAQGVAY A L + +TIVMP P K T+ +GA VVL+G L Sbjct: 70 K-KNGVIAVSAGNHAQGVAYAASTLNIKSTIVMPETAPASKYLATKSYGAEVVLYGKYLH 128 Query: 135 AARTHAYELAEKEGLTFVHPYDDEAIIAGQGTVALEMMKAVPDLDCLVVSIGGGGLLAGM 194 + A EL + GL FVHPY D +I GQGT+ LE+ PD + + GG + Sbjct: 129 ESMKKAEELIQNTGLIFVHPYSDLDVITGQGTIGLELYDIEPDYVIIPIGGGGLISGISI 188 Query: 195 AVAARAIKPEIEIVGVQTRRFPTM-VNAVKGTEHPVGAS-TIAEGIAVGTPGTLTRAIIA 252 A+ R P ++I+GVQ+ P+M V+ G + S +IA+GI V +P LT +II Sbjct: 189 ALKYRF--PNVKIIGVQSSSSPSMKVSKDLGRLVEIEPSYSIADGILVKSPSELTFSIIN 246 Query: 253 READELLLVDEGDIEQAVLMLLEIEKTLVEGAGAAGLAALVRYPDRFRG--KRVGLVLSG 310 D+++LVD+ +I +A+++LLE KTL EGAGAA LA+L+ + G K+V ++SG Sbjct: 247 ELVDDIVLVDDEEIAEAIVLLLERSKTLAEGAGAAALASLISGKVKVNGIDKKVISLVSG 306 Query: 311 GNIDPLLLTAIIERGMVRAGRLARVKVSSRDVPGTLARITGIVAEAGANVDEVHHQR 367 GNID LL+ + E+ + R R+ +V+V D PG L ++ V + N+ ++ H R Sbjct: 307 GNIDLSLLSTLTEKFLYRQKRVVKVRVIVPDKPGQLNKVLSYVVKIRGNIIDIVHDR 363