BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0005.p (467 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0488 [T] COG0642 Signal transduction histidine kinase Rso Ral... 345 1e-94 PA4886 [T] COG0642 Signal transduction histidine kinase Pae Pseu... 283 5e-76 ZybcZ [T] COG0642 Signal transduction histidine kinase EcZ Esche... 244 3e-64 ECs0608 [T] COG0642 Signal transduction histidine kinase Ecs Esc... 244 3e-64 RSp0654 [T] COG0642 Signal transduction histidine kinase Rso Ral... 244 4e-64 ybcZ [T] COG0642 Signal transduction histidine kinase Eco Escher... 243 7e-64 PA1438 [T] COG0642 Signal transduction histidine kinase Pae Pseu... 236 7e-62 STM1095 [T] COG0642 Signal transduction histidine kinase Sty Sal... 222 2e-57 PA2810 [T] COG0642 Signal transduction histidine kinase Pae Pseu... 221 3e-57 PA2524 [T] COG0642 Signal transduction histidine kinase Pae Pseu... 218 2e-56 >RSp0488 [T] COG0642 Signal transduction histidine kinase Rso Ralstonia solanacearum Length = 465 Score = 345 bits (885), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 203/462 (43%), Positives = 282/462 (61%), Gaps = 7/462 (1%) Query: 6 PASLSLRLVALFGLLAMVILAALGTYLSHSLHVQLERRDDEELAGKCRSINHLVEHAASL 65 PASL+ RLV F L+A V+L GTYL ++L+ QL DD L GK + H + S+ Sbjct: 5 PASLAARLVLAFVLVAGVMLTGAGTYLYYALNAQLRATDDAMLLGKIVQLRHCAKDTQSI 64 Query: 66 EDIL--ARRHLVLDTLTGHDQLLVRIARADGSTLLESHDPTRTPPGIDLSQVDIRAWDSI 123 +DI+ ARR+ + ++GH+ L++R+ DG TL+E++ D+ A +S Sbjct: 65 DDIVRDARRYT--EVVSGHEGLILRVIGPDGRTLVEANPEGEPVAAPAAVPPDVLASESA 122 Query: 124 QS--WKLGDLRARYVASKP-VTRSGEQAVVLVVRTASDRMLLLAEYRSDVWWAAGVGALL 180 W + +R +A++ + + VLV + R L+A YR ++ A G Sbjct: 123 LHTWWSRTGIASRAIAAQARLGNHRDTVTVLVAQDGDSRAALMASYRRHIFLAVIAGVAA 182 Query: 181 AILMSYFLVRSGLRPLRTMAAQTRAVSANRLDTRLDLQAAPRELHEIVESFNEMLDRLHR 240 L+S +LVRS L+ L + Q +V ++LDTRL L+ APREL +++ + N ML RL Sbjct: 183 VALLSLWLVRSTLKGLARIGRQAASVVPSQLDTRLTLEGAPRELSDLLAALNAMLTRLQD 242 Query: 241 SFQQLSQFSADLAHDVRTPLNNLMVQTQVALGKPRGIDEYQALLSSNIEEYERLSRMMES 300 F +LSQFSADLAHD RTPL NL+ QT+V L PR EY+A+L S++EEY RLSRM+E Sbjct: 243 GFARLSQFSADLAHDFRTPLANLIGQTEVTLAHPRPAGEYRAVLESSLEEYARLSRMIED 302 Query: 301 MLFLARAENAHVVLQWQELDVAQELTRIADYFEGIADEAQVRLVVQGAGRLQADATLLRR 360 MLFLARA++A V L LD E+ + DYFE +A + + + V G GR++AD TLLRR Sbjct: 303 MLFLARADHARVALSVAPLDARHEIQVLVDYFEAVAADRDITIQVCGNGRVRADLTLLRR 362 Query: 361 AVGNLVANAIRYTPADGVIRLQVDAAGDGMEISVSNPGAGIPAEQLERLFDRFYRADPSR 420 A+ NL+ NA+R+TP I + V I+V NPG GIPA L LFDRFYR DP+R Sbjct: 363 AINNLLDNALRHTPGGARIDVAVQVLPHSTAIAVRNPGPGIPAASLPLLFDRFYRGDPAR 422 Query: 421 SSAGGSSGLGLAIVRSIMMLHGGQASVTSSPGQLTVFSLRFP 462 +++ S+GLGLAIV++IM LHGG A +S PG LT F L FP Sbjct: 423 ANSERSAGLGLAIVQTIMDLHGGTAQASSPPGGLTEFRLIFP 464 >PA4886 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 463 Score = 283 bits (725), Expect = 5e-76, Method: Compositional matrix adjust. Identities = 175/439 (39%), Positives = 264/439 (60%), Gaps = 6/439 (1%) Query: 29 GTYLSHSLHVQLERRDDEELAGKCRSINHLVEHAASLEDILARRHLVLDTLTGHDQLLVR 88 G YL S+ + RR D +AG+ +L+ +L ++ AR L + + G++Q ++ Sbjct: 27 GFYLYRSVEEAMLRRSDVMVAGRVEHFRNLLRDNLTLAELKARPRL-FENMLGNEQDILL 85 Query: 89 IARADGSTLLESHDPTRTPPGIDLSQVDIRAWDSIQSWKL--GDLRARYVASKPVTRSGE 146 + + + ++ + P + + S+ L + R +A++ + E Sbjct: 86 LGQPGEAPIVAVNPRHERLPSLRVVAAGQALNPSVVHAALTHDGIPMRVLAAEVLVGGRE 145 Query: 147 QAVVLVVRTASDRMLLLAEYRSDVWWAAGVGALLAILMSYFLVRSGLRPLRTMAAQTRAV 206 + +LA+YR V A + L L+ + ++R GLRPLRT+AA+ + Sbjct: 146 PLQITAAHLLLGETRMLAQYRDRVIAAVLLAFLGTALLGWLVLRHGLRPLRTLAAKAAEI 205 Query: 207 SANRLDTRLDLQAAPRELHEIVESFNEMLDRLHRSFQQLSQFSADLAHDVRTPLNNLMVQ 266 LDTRLD+ AAP EL ++ +SFN ML+RL +Q+L QFSADLAH++RTP+ +LM Sbjct: 206 HPTSLDTRLDVAAAPAELQQVAQSFNAMLERLDDGYQRLQQFSADLAHEIRTPIGSLMGH 265 Query: 267 TQVALGKPRGIDEYQALLSSNIEEYERLSRMMESMLFLARAENAHVVLQWQELDVAQELT 326 QVAL +PR +EYQAL++SN EE ER++RM+ES+LFLARA++ ++ LD+ +EL Sbjct: 266 GQVALRQPRSNEEYQALIASNQEELERIARMVESILFLARADDVRAAVERSRLDLGEELR 325 Query: 327 RIADYFEGIADEAQVRLVVQGAGRLQADATLLRRAVGNLVANAIRYTPADGVIRLQVDAA 386 R A+YFEG+A+E + L VQ +G+L+AD L RRA+ NL+ANAIRY AD +I ++ Sbjct: 326 RQAEYFEGLAEERGLSLDVQVSGQLRADPQLFRRALSNLLANAIRYASADSLIEVRGLRR 385 Query: 387 GDGMEISVSNPGAGIPAEQLERLFDRFYRADPSRSSAGGSSGLGLAIVRSIMMLHGGQAS 446 +SV N +PAE L RLFDRFYR D +RS A SSGLGLAIV++IM LHGG+A Sbjct: 386 SGEFLLSVENACDRLPAEPLSRLFDRFYRGDAARSDA-QSSGLGLAIVQAIMRLHGGRAE 444 Query: 447 VTS-SPGQLTVFSLRFPGR 464 ++ +PG++ F L FP + Sbjct: 445 ASAPAPGRIR-FDLAFPAQ 462 >ZybcZ [T] COG0642 Signal transduction histidine kinase EcZ Escherichia coli O157:H7 EDL933 Length = 482 Score = 244 bits (623), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 160/495 (32%), Positives = 257/495 (51%), Gaps = 58/495 (11%) Query: 6 PASLSLRLVALFGLLAMVILAALGTYLSHSLHVQLERRDDEELAGKCRSINHLVEHAASL 65 P SL+ RL L + A + HS+ V +D IN L E +A+L Sbjct: 9 PFSLATRLTFFISLATIAAFFAFAWIMIHSVKVHFAEQD----------INDLKEISATL 58 Query: 66 EDIL-------ARRHLVL-DTLTGHDQLLVRIARADGSTLLES----------------- 100 E +L ARR + L D ++G+ +L+ +A + G T+ S Sbjct: 59 ERVLNHPDETQARRLMTLEDIVSGYSNVLISLADSHGKTVYHSPGAPDIREFARDAIPDK 118 Query: 101 ----------HDPTRTPPGIDLSQVDIRAWDSIQSWKLGDLRARYVASKPVTRSGEQAVV 150 PT PG ++ W I S +G L V KP+ + Sbjct: 119 DARGGEVFLLSGPTMMMPGHGHGHMEHSNWRMI-SLPVGPL----VDGKPI------YTL 167 Query: 151 LVVRTASDRMLLLAEYRSDVWWAAGVGALLAILMSYFLVRSGLRPLRTMAAQTRAVSANR 210 + + + + + + + A V ++L + + V G P+R+++ Q + +++ Sbjct: 168 YIALSIDFHLHYINDLMNKLIMTASVISILIVFIVLLAVHKGHAPIRSVSRQIQNITSKD 227 Query: 211 LDTRLDLQAAPRELHEIVESFNEMLDRLHRSFQQLSQFSADLAHDVRTPLNNLMVQTQVA 270 LD RLD Q P EL ++V SFN M++R+ F + S FSAD+AH++RTP+ NL+ QT++A Sbjct: 228 LDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTPITNLITQTEIA 287 Query: 271 LGKPRGIDEYQALLSSNIEEYERLSRMMESMLFLARAENAHVVLQWQELDVAQELTRIAD 330 L + R E + +L SN+EE R+++M+ MLFLA+A+N ++ + + L++A E+ ++ D Sbjct: 288 LSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKKMLNLADEVGKVFD 347 Query: 331 YFEGIADEAQVRLVVQG-AGRLQADATLLRRAVGNLVANAIRYTPADGVIRLQVDAAGDG 389 +FE +A++ V L G ++ D +LRRA+ NL++NA+RYTP I ++ Sbjct: 348 FFEALAEDRGVELQFVGDECQVAGDPLMLRRALSNLLSNALRYTPPGEAIVVRCQTVDHL 407 Query: 390 MEISVSNPGAGIPAEQLERLFDRFYRADPSRSSAGGSSGLGLAIVRSIMMLHGGQASVTS 449 +++ V NPG I E L RLFDRFYR DPSR G SG+GLAIV+SI++ H G +VTS Sbjct: 408 VQVIVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVVAHKGTVAVTS 467 Query: 450 SPGQLTVFSLRFPGR 464 + + T F + P R Sbjct: 468 N-ARGTRFVIVLPER 481 >ECs0608 [T] COG0642 Signal transduction histidine kinase Ecs Escherichia coli O157:H7 Length = 482 Score = 244 bits (623), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 160/495 (32%), Positives = 257/495 (51%), Gaps = 58/495 (11%) Query: 6 PASLSLRLVALFGLLAMVILAALGTYLSHSLHVQLERRDDEELAGKCRSINHLVEHAASL 65 P SL+ RL L + A + HS+ V +D IN L E +A+L Sbjct: 9 PFSLATRLTFFISLATIAAFFAFAWIMIHSVKVHFAEQD----------INDLKEISATL 58 Query: 66 EDIL-------ARRHLVL-DTLTGHDQLLVRIARADGSTLLES----------------- 100 E +L ARR + L D ++G+ +L+ +A + G T+ S Sbjct: 59 ERVLNHPDETQARRLMTLEDIVSGYSNVLISLADSHGKTVYHSPGAPDIREFARDAIPDK 118 Query: 101 ----------HDPTRTPPGIDLSQVDIRAWDSIQSWKLGDLRARYVASKPVTRSGEQAVV 150 PT PG ++ W I S +G L V KP+ + Sbjct: 119 DARGGEVFLLSGPTMMMPGHGHGHMEHSNWRMI-SLPVGPL----VDGKPI------YTL 167 Query: 151 LVVRTASDRMLLLAEYRSDVWWAAGVGALLAILMSYFLVRSGLRPLRTMAAQTRAVSANR 210 + + + + + + + A V ++L + + V G P+R+++ Q + +++ Sbjct: 168 YIALSIDFHLHYINDLMNKLIMTASVISILIVFIVLLAVHKGHAPIRSVSRQIQNITSKD 227 Query: 211 LDTRLDLQAAPRELHEIVESFNEMLDRLHRSFQQLSQFSADLAHDVRTPLNNLMVQTQVA 270 LD RLD Q P EL ++V SFN M++R+ F + S FSAD+AH++RTP+ NL+ QT++A Sbjct: 228 LDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTPITNLITQTEIA 287 Query: 271 LGKPRGIDEYQALLSSNIEEYERLSRMMESMLFLARAENAHVVLQWQELDVAQELTRIAD 330 L + R E + +L SN+EE R+++M+ MLFLA+A+N ++ + + L++A E+ ++ D Sbjct: 288 LSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKKMLNLADEVGKVFD 347 Query: 331 YFEGIADEAQVRLVVQG-AGRLQADATLLRRAVGNLVANAIRYTPADGVIRLQVDAAGDG 389 +FE +A++ V L G ++ D +LRRA+ NL++NA+RYTP I ++ Sbjct: 348 FFEALAEDRGVELQFVGDECQVAGDPLMLRRALSNLLSNALRYTPPGEAIVVRCQTVDHL 407 Query: 390 MEISVSNPGAGIPAEQLERLFDRFYRADPSRSSAGGSSGLGLAIVRSIMMLHGGQASVTS 449 +++ V NPG I E L RLFDRFYR DPSR G SG+GLAIV+SI++ H G +VTS Sbjct: 408 VQVIVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVVAHKGTVAVTS 467 Query: 450 SPGQLTVFSLRFPGR 464 + + T F + P R Sbjct: 468 N-ARGTRFVIVLPER 481 >RSp0654 [T] COG0642 Signal transduction histidine kinase Rso Ralstonia solanacearum Length = 466 Score = 244 bits (622), Expect = 4e-64, Method: Compositional matrix adjust. Identities = 155/465 (33%), Positives = 251/465 (53%), Gaps = 20/465 (4%) Query: 8 SLSLRLVALFGLLAMVILAALGTYLSHSLHVQLERRDDEELAGKCRSINHLVEHAASLED 67 SL+ RL ALF L + +L LG ++ ++ D L I +VE + + Sbjct: 6 SLTARLTALFSLCSAAVLLGLGVVIALAMEQHFAVEDFTALGEHVSVIGKIVESGPAPQ- 64 Query: 68 ILARRHLVLDTLTGHDQLLVRIARADGSTLLESHDPTRTPPGIDLSQVD-----IRAWDS 122 AR + D L + RI D L S G D D R Sbjct: 65 AEAR---IRDALQHRTGFVARILGPDRRALYASD-------GFDFRAADEALARARPGSD 114 Query: 123 IQSWKLGDLRARYVASKPVTRSGEQAV--VLVVRTASDRMLLLAEYRSDVWWAAGVGALL 180 W G + R + + R G +LV L +R + + + AL Sbjct: 115 RLVWAQGGQQYRAMHTTVALRDGTAGRLDMLVAMNTDIHAHFLHTFRGTLAFYIALAALA 174 Query: 181 AILMSYFLVRSGLRPLRTMAAQTRAVSANRLDTRLDLQAAPRELHEIVESFNEMLDRLHR 240 + + ++ R GL PLRT+A++ R V+A++LD R+ + P E+ ++ + N ML+RL Sbjct: 175 SGVFGWWAARRGLAPLRTLASRARTVTADKLDERMPVDTVPAEVADLAVTLNAMLERLQH 234 Query: 241 SFQQLSQFSADLAHDVRTPLNNLMVQTQVALGKPRGIDEYQALLSSNIEEYERLSRMMES 300 F++LS FS D+AH++RTP+ NL+ QT+V L +PR +Y+ +L+SN EE +RL+RM+ Sbjct: 235 DFRRLSDFSTDIAHEIRTPITNLLTQTEVVLSQPREGAKYRDVLTSNAEELQRLARMVSD 294 Query: 301 MLFLARAENAHVVLQWQELDVAQELTRIADYFEGIADEAQVRLVVQGAGRLQADATLLRR 360 ML+LA+ E++ + +++ +A EL + ++++ +A++ VRL ++G GR+ D +LRR Sbjct: 295 MLYLAKMEHSLTLPSAEDIHLADELRALFEFYDALAEDKAVRLELRGDGRVSGDRLMLRR 354 Query: 361 AVGNLVANAIRYTPADGVIRLQVDAAGDGMEISVSNPGAGIPAEQLERLFDRFYRADPSR 420 A+ NL++NAIR+ P G + + + G G+ +SV N G IP + L R+F+RFYRAD SR Sbjct: 355 ALSNLLSNAIRHAPPRGAVLVSIADTGHGVTVSVDNDGDEIPPQVLSRIFERFYRADKSR 414 Query: 421 S-SAGGSSGLGLAIVRSIMMLHGGQASVTSSPGQLTVFSLRFPGR 464 + S+GLGLAI ++I++ HGG +V+ G+ T F+L F R Sbjct: 415 ARPESDSTGLGLAITKAIVVAHGGSIAVSRVGGR-TRFALHFARR 458 >ybcZ [T] COG0642 Signal transduction histidine kinase Eco Escherichia coli K12 Length = 480 Score = 243 bits (620), Expect = 7e-64, Method: Compositional matrix adjust. Identities = 155/480 (32%), Positives = 250/480 (52%), Gaps = 57/480 (11%) Query: 6 PASLSLRLVALFGLLAMVILAALGTYLSHSLHVQLERRDDEELAGKCRSINHLVEHAASL 65 P SL+ RL L + A + HS+ V +D IN L E +A+L Sbjct: 9 PFSLATRLTFFISLATIAAFFAFAWIMIHSVKVHFAEQD----------INDLKEISATL 58 Query: 66 EDIL-------ARRHLVL-DTLTGHDQLLVRIARADGSTLLES----------------- 100 E +L ARR + L D ++G+ +L+ +A + G T+ S Sbjct: 59 ERVLNHPDETQARRLMTLEDIVSGYSNVLISLADSQGKTVYHSPGAPDIREFTRDAIPDK 118 Query: 101 ----------HDPTRTPPGIDLSQVDIRAWDSIQSWKLGDLRARYVASKPVTRSGEQAVV 150 PT PG ++ W I + +G L V KP+ + Sbjct: 119 DAQGGEVYLLSGPTMMMPGHGHGHMEHSNWRMI-NLPVGPL----VDGKPI------YTL 167 Query: 151 LVVRTASDRMLLLAEYRSDVWWAAGVGALLAILMSYFLVRSGLRPLRTMAAQTRAVSANR 210 + + + + + + + A V ++L + + V G P+R+++ Q + +++ Sbjct: 168 YIALSIDFHLHYINDLMNKLIMTASVISILIVFIVLLAVHKGHAPIRSVSRQIQNITSKD 227 Query: 211 LDTRLDLQAAPRELHEIVESFNEMLDRLHRSFQQLSQFSADLAHDVRTPLNNLMVQTQVA 270 LD RLD Q P EL ++V SFN M++R+ F + S FSAD+AH++RTP+ NL+ QT++A Sbjct: 228 LDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTPITNLITQTEIA 287 Query: 271 LGKPRGIDEYQALLSSNIEEYERLSRMMESMLFLARAENAHVVLQWQELDVAQELTRIAD 330 L + R E + +L SN+EE R+++M+ MLFLA+A+N ++ + + L++A E+ ++ D Sbjct: 288 LSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKKMLNLADEVGKVFD 347 Query: 331 YFEGIADEAQVRL-VVQGAGRLQADATLLRRAVGNLVANAIRYTPADGVIRLQVDAAGDG 389 +FE +A++ V L V ++ D +LRRA+ NL++NA+RYTP I ++ Sbjct: 348 FFEALAEDRGVELRFVGDKCQVAGDPLMLRRALSNLLSNALRYTPTGETIVVRCQTVDHL 407 Query: 390 MEISVSNPGAGIPAEQLERLFDRFYRADPSRSSAGGSSGLGLAIVRSIMMLHGGQASVTS 449 +++ V NPG I E L RLFDRFYR DPSR G SG+GLAIV+SI++ H G +VTS Sbjct: 408 VQVIVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVVAHKGTVAVTS 467 >PA1438 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 481 Score = 236 bits (603), Expect = 7e-62, Method: Compositional matrix adjust. Identities = 169/469 (36%), Positives = 251/469 (53%), Gaps = 28/469 (5%) Query: 8 SLSLRLVALFGLLAMVILAALGTYLSHSLHVQLERRDDEELAGKCRSINHLVEHAASLED 67 SLS RL +F A+VI A +GT L L Q ER E+ + ++ +++H Sbjct: 12 SLSTRLAGMFAGAAVVIFALIGTMLYCILDRQTERLQQGEVDVRFNMVSRMLDHPD---- 67 Query: 68 ILARR--HL--VLDTLTGHDQLLVRIARADGSTLLESHDPTRTPPGIDLSQVDIRAWDSI 123 LA R HL LD L+ +L+ ++S DP R G V D Sbjct: 68 -LAERWPHLQGKLDNLSQEYELI--------RFWIDSDDP-RYHYGRFSEPVQRLIADGA 117 Query: 124 QSWKLGDLRARYVASKPV----TRSGEQAVVLVVRTASDRMLLLAEYRSDVWWAAGV--- 176 ++L RY + V R G + V TA D S + W G+ Sbjct: 118 GRYELELPEHRYALTARVGVLPAREGRPRLTYV--TAIDSAAFHEARTSTLKWLLGLSAL 175 Query: 177 GALLAILMSYFLVRSGLRPLRTMAAQTRAVSANRLDTRLDLQAAPRELHEIVESFNEMLD 236 G LLA L+ +++ R GL P+ ++ + R +S +L RL L P EL E+V +FN LD Sbjct: 176 GVLLASLLGHWIARLGLWPVHRLSEEARRISPRQLSQRLQLSPLPAELRELVGAFNGALD 235 Query: 237 RLHRSFQQLSQFSADLAHDVRTPLNNLMVQTQVALGKPRGIDEYQALLSSNIEEYERLSR 296 RL +++ +L F+AD+AH++RTPL NL+ QTQVAL + R + Y+ +L SN+EE ERL Sbjct: 236 RLEQAYVRLESFNADVAHELRTPLTNLIGQTQVALSRERSGEHYEEVLQSNLEELERLRA 295 Query: 297 MMESMLFLARAENAHVVLQWQELDVAQELTRIADYFEGIADEAQVRLVVQGAGRLQADAT 356 ++ MLFLARA+ + + +E +A E+ D+ E I DEA V + V+G R + Sbjct: 296 IVNDMLFLARADQGRLACEREETSLAGEIATTVDFLEVIFDEAGVGIEVRGEARALVERA 355 Query: 357 LLRRAVGNLVANAIRYTPADGVIRLQVDAAGDGMEISVSNPGAGIPAEQLERLFDRFYRA 416 L +RAV NL+ NA ++T A G +R+ V+ GD + ++VSNPG I E LF+RFYR Sbjct: 356 LFQRAVTNLLYNAAQHTAAGGTLRVGVERRGDEVRVAVSNPGVPIADEHRRHLFERFYRV 415 Query: 417 DPSRSSAGGSSGLGLAIVRSIMMLHGGQASVTSSPGQLTV-FSLRFPGR 464 D +RS++ + GLGL+IV+++ +HGG V S+ G T F++ P R Sbjct: 416 DAARSNSEANHGLGLSIVKAVASMHGGSVFVDSADGWNTFGFTVLSPER 464 >STM1095 [T] COG0642 Signal transduction histidine kinase Sty Salmonella typhimurium LT2 Length = 454 Score = 222 bits (565), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 156/458 (34%), Positives = 259/458 (56%), Gaps = 16/458 (3%) Query: 8 SLSLRLVALFGLLAMVILAALGT--YLSHSLHVQLERRDDEELAGKCRSINHLVEHAASL 65 S++LRL F +A++ILA G L ++L +L RDD L + + L+ A Sbjct: 5 SMTLRLTISF--IAILILACTGISWTLYNALSKELTYRDDMTLINRAAQMQQLLLDGARP 62 Query: 66 EDILARRHLVLDTLTGHDQLLVRIARADGSTLLESHDPTRTPPGIDLSQVDIRAWDSIQS 125 E++ + ++DT D LL+ A + S P + I L++ R Q+ Sbjct: 63 ENLPLYFNRMVDT--KQDILLIHSATGHNVAINHSGIPDQRFNEIPLTKNITRETLFRQA 120 Query: 126 WKLGDLRARYVASKPVTRSGEQAVVLVV-RTASDRMLLLAEYRSDVWWAAGVGALLAILM 184 + +L A V++ RSG+ + L + R A++R +LA+YR + + + L+ + Sbjct: 121 VQGTELTAVRVSA----RSGDDPLTLTIARLATERRQMLAQYRRNSLLMSLIAILVCSAL 176 Query: 185 SYFLVRSGLRPLRTMAAQTRAVSANRLDTRLDLQAAPRELHEIVESFNEMLDRLHRSFQQ 244 S ++R+GLR + +++ T A + L L QA P EL + ++ N M +L F++ Sbjct: 177 SPLVIRNGLRAITSLSRLTAATDSGTLRQPLAEQALPVELRPLGQALNTMRQKLSDDFER 236 Query: 245 LSQFSADLAHDVRTPLNNLMVQTQVALGKPRGIDEYQALLSSNIEEYERLSRMMESMLFL 304 L+QF+ DLAH++RTP+N L+ + QV L + R +EYQ L NIEE E LSR+ E++LFL Sbjct: 237 LNQFADDLAHELRTPVNILLGKNQVMLSQERSAEEYQQALVDNIEELEGLSRLTENILFL 296 Query: 305 ARAENAHVVLQWQELDVAQELTRIADYFEGIADEAQVRLVVQGAGRLQADATLLRRAVGN 364 ARAE+ ++ ++ Q + + + + DY +A+E ++ + Q G + AD LL+R + N Sbjct: 297 ARAEHQNIAVKKQPVSLNALVENMLDYLSPLAEEKRICFINQCQGTVWADEILLQRVLSN 356 Query: 365 LVANAIRYTPADGVIRLQVDAAGDGMEISVSNPGAGIPAEQLERLFDRFYRADPSRSSAG 424 L+ NAIRY+ + VIR++ + EI V+NPG+ PA+ ++LF RF+R D +R +AG Sbjct: 357 LLTNAIRYSDENAVIRIESAYDDNVAEIRVANPGSH-PADA-DKLFRRFWRGDNARHTAG 414 Query: 425 GSSGLGLAIVRSIMMLHGGQASVTSSPGQLTVFSLRFP 462 GLGL++V +I +LHGG AS + + +FS+R P Sbjct: 415 --FGLGLSLVNAIALLHGGSASYRYA-DEHNIFSVRLP 449 >PA2810 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 443 Score = 221 bits (563), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 128/311 (41%), Positives = 184/311 (59%), Gaps = 6/311 (1%) Query: 152 VVRTASDRMLLLAEYRSDVWWAAGVGALLAILMSYFLVRSGLRPLRTMAAQTRAVSANRL 211 V+ S L R +W + AL L+ + + L PLR M VSAN L Sbjct: 133 VILDISHHQHFLQRMRQLIWLTMSLSALATALLGAWATGASLAPLRRMREVAARVSANSL 192 Query: 212 DTRLDLQAAPRELHEIVESFNEMLDRLHRSFQQLSQFSADLAHDVRTPLNNLMVQTQVAL 271 TRLD P EL + N ML RL +FQ+LS FSAD+AH++RTPL +L+ QTQV L Sbjct: 193 TTRLDASRMPEELRGLAGELNAMLARLEEAFQRLSAFSADIAHELRTPLTSLLTQTQVVL 252 Query: 272 GKPRGIDEYQALLSSNIEEYERLSRMMESMLFLARAENAHVVLQWQELDVAQELTRIADY 331 +PR +++Y+ L N+EE ERL+ M+ ML LA+A++ + Q LD+ E+ + ++ Sbjct: 253 SRPRSLEDYREALHGNLEELERLTAMVNDMLLLAKADHGLLAPSRQALDLGAEVDSLLEF 312 Query: 332 FEGIADEAQVRLVVQGAGRLQADATLLRRAVGNLVANAIRYTPADGVIRLQVDAAGDGME 391 ++ +A++ +RL+ +G+ L D +LRR + NL+ NA+R+T G IR+++ GD Sbjct: 313 YQPLAEDRDIRLLREGSLSLPGDRGMLRRVLANLLDNALRFTADGGEIRIRL---GD-RR 368 Query: 392 ISVSNPGAGIPAEQLERLFDRFYRADPSRSSAGGS-SGLGLAIVRSIMMLHGGQASVTSS 450 +SV N G IP E+L RLFDRFYRADP+R G +GLGLAI RSI+ HGG+ S+ Sbjct: 369 LSVENQGPAIPPERLPRLFDRFYRADPARREGQGEHAGLGLAICRSIVQAHGGEIRCESA 428 Query: 451 PGQLTVFSLRF 461 G T F + F Sbjct: 429 DG-WTRFVIDF 438 >PA2524 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 472 Score = 218 bits (556), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 162/441 (36%), Positives = 232/441 (52%), Gaps = 19/441 (4%) Query: 39 QLERRDDEELAGKCRSINHLVEHAASL-EDILARRHLVLDTLTGHDQLLVRIARA-DGST 96 +LE R+ E L K I H +E L D + H + D L H L + I + G Sbjct: 37 ELEARERENLQLKLEQIRHSLEDDLDLRSDPAVQAHALQDQLVAHSGLHLSILDSRSGQP 96 Query: 97 LLESHDPTRTPPGIDLS-----QVDIRAWDSIQSWKLG-DLRARYVASKPVTRSGEQAVV 150 L+ D + + Q D R QSW G D R + + ++G V Sbjct: 97 LMSFGDQAAASVAANRALLARLQADARQ-PVFQSWSTGNDQRLLSIGASMRMKNGTPVQV 155 Query: 151 LVV--RTASDRMLLLAEYRSDVWWAAGVGALLAILMSYFLVRSGLRPL---RTMAAQTRA 205 L+ R A +R LL R+ + + L+A L ++++VR+GL PL R +AAQ Sbjct: 156 LLSSERNADER-LLDGFLRATLLALPFLLPLIA-LAAWWVVRAGLEPLNRFRRVAAQ--- 210 Query: 206 VSANRLDTRLDLQAAPRELHEIVESFNEMLDRLHRSFQQLSQFSADLAHDVRTPLNNLMV 265 VS L R+ Q PREL + SFN ML RL +QLSQFS DLAH++R P+ NL+V Sbjct: 211 VSPQDLSYRIPEQNLPRELDSLARSFNHMLGRLEDGVRQLSQFSDDLAHELRAPICNLLV 270 Query: 266 QTQVALGKPRGIDEYQALLSSNIEEYERLSRMMESMLFLARAENAHVVLQWQELDVAQEL 325 + QV L + R Y+ L SN EE ERLSR++ MLFL + +N + Q+ + + ++ Sbjct: 271 RNQVLLSQHRDGAAYREALESNAEELERLSRIVTDMLFLVQVDNPAIQAQFGCVALHEQA 330 Query: 326 TRIADYFEGIADEAQVRLVVQGAGRLQADATLLRRAVGNLVANAIRYTPADGVIRLQVDA 385 ++ D +E +A++ V L + G G D +++RA+ NLV+NA+R+TP G I +++ Sbjct: 331 AKVIDLYEMVAEDKGVELRLSGNGFAHGDNLMIQRAISNLVSNAVRHTPQGGRIDVRIGE 390 Query: 386 AGDGMEISVSNPGAGIPAEQLERLFDRFYRADPSRSSAGGSSGLGLAIVRSIMMLHGGQA 445 E+ VSN G GIP E L LF+RFYR ++ A +GLGLAIV+SIM HGG+A Sbjct: 391 RAGHTEVRVSNDGPGIPPEYLPHLFERFYRRAGRQTGAQAGTGLGLAIVQSIMAYHGGRA 450 Query: 446 SVTSSPGQLTVFSLRFPGRSA 466 S P Q T L FP A Sbjct: 451 EAESVPQQKTHLRLLFPSTGA 471