BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0246.p (292 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PM1366 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and relate... 292 6e-79 SMb20668 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and rela... 291 9e-79 STM2918 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and relat... 290 2e-78 ygbJ [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related ... 283 2e-76 BMEII1090 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and rel... 283 4e-76 HI1010 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and relate... 275 1e-73 SMc00274 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and rela... 214 2e-55 STM3248 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and relat... 175 1e-43 yhaE [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related ... 167 2e-41 ZyhaE [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related... 167 2e-41 >PM1366 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Pmu Pasteurella multocida Length = 301 Score = 292 bits (748), Expect = 6e-79, Method: Compositional matrix adjust. Identities = 164/291 (56%), Positives = 213/291 (73%), Gaps = 1/291 (0%) Query: 1 VIGLGAMGYGVASSLLRAGFNVHACDVRKEVLDKFAAAGGVACANPA-ELAGKVDVVITL 59 VIGLGAMG G A S +RAG + D+ L+K A G + A + A ++D V+ L Sbjct: 9 VIGLGAMGMGAAQSCIRAGLTTYGADLNPLALEKLKAEGAKGVSQSAVDFAQELDAVLLL 68 Query: 60 VVNAAQTETVLFGDNGAVSAMKPGSVVISSATVAPDFAIELGKRLAEKGLLLLDAPVSGG 119 VVNA+Q TVLFG+ G S +KPG+ V+ S+T++ A ++ ++L GL++LDAPVSGG Sbjct: 69 VVNASQVNTVLFGEKGLASHLKPGTAVMVSSTISAQDAQQISQKLTGLGLVMLDAPVSGG 128 Query: 120 AARAASGEMTMMTSGPAEVYAKIEDVLAGMAGKVYRLGDTHGIGSKVKIINQLLAGVHIA 179 AA+AA+GEMT+M SG + + K++ VL +AGKVY +G+ G+G+ VKII+QLLAGVHIA Sbjct: 129 AAKAAAGEMTVMASGSQQAFTKLQPVLDAVAGKVYNIGEEIGLGATVKIIHQLLAGVHIA 188 Query: 180 ASAEAMALGLREGVNPDALYEVITHSAGNSWMFENRVPHILNGDYTPLSAVDIFVKDLGL 239 A AEAMAL R G+ D +Y+V+TH+AGNSWMFENR+ H++ GDYTPLS VDIFVKDLGL Sbjct: 189 AGAEAMALAARAGIPLDLMYDVVTHAAGNSWMFENRMKHVVEGDYTPLSMVDIFVKDLGL 248 Query: 240 VLDTARRSKFPLPLSAAAHQMFMMASTAGHGGEDDSAVIKIFPGIDLPPAK 290 V DTA+ KFPLPL++ A MF AS AG+G EDDSAVIKIF GI+LP K Sbjct: 249 VTDTAKALKFPLPLASTAFNMFTSASNAGYGKEDDSAVIKIFSGIELPQKK 299 >SMb20668 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Sme Sinorhizobium meliloti Length = 301 Score = 291 bits (746), Expect = 9e-79, Method: Compositional matrix adjust. Identities = 150/281 (53%), Positives = 200/281 (71%) Query: 1 VIGLGAMGYGVASSLLRAGFNVHACDVRKEVLDKFAAAGGVACANPAELAGKVDVVITLV 60 V+GLG+MG+G+A S+ AG +V DV +++F A GG P E D+++++V Sbjct: 7 VLGLGSMGFGMACSMKSAGLDVLGYDVAPPAVERFVAEGGRGAGTPGEAVTGADIIVSIV 66 Query: 61 VNAAQTETVLFGDNGAVSAMKPGSVVISSATVAPDFAIELGKRLAEKGLLLLDAPVSGGA 120 V+ AQTE VLFG NG AMKPG+ ISSAT+ P A +L +RL GL LDAP+SGGA Sbjct: 67 VSGAQTEAVLFGPNGVAGAMKPGAAFISSATMDPAIARDLAQRLEALGLHYLDAPISGGA 126 Query: 121 ARAASGEMTMMTSGPAEVYAKIEDVLAGMAGKVYRLGDTHGIGSKVKIINQLLAGVHIAA 180 A+AA GE+T+M SG + +A L MA KVY LG T G G+ K+INQLLAGVHIAA Sbjct: 127 AKAAKGELTIMASGSPQAFAAARPALDAMAAKVYELGGTAGTGAAFKMINQLLAGVHIAA 186 Query: 181 SAEAMALGLREGVNPDALYEVITHSAGNSWMFENRVPHILNGDYTPLSAVDIFVKDLGLV 240 + EA+A ++G++ D +YEVIT SAGNSWMFENR+PH+L GDY PLSA++IFVKDLG+V Sbjct: 187 ACEAIAFAAKQGLDLDKVYEVITASAGNSWMFENRIPHVLAGDYAPLSAIEIFVKDLGIV 246 Query: 241 LDTARRSKFPLPLSAAAHQMFMMASTAGHGGEDDSAVIKIF 281 D AR ++P+PL AAA QM++ AS AG G +DDS++ +++ Sbjct: 247 QDMARAERYPVPLVAAALQMYLAASGAGMGRDDDSSLARLY 287 >STM2918 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Sty Salmonella typhimurium LT2 Length = 307 Score = 290 bits (743), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 161/288 (55%), Positives = 202/288 (70%), Gaps = 1/288 (0%) Query: 1 VIGLGAMGYGVASSLLRAGFNVHACDVRKEVLDKFAAAGGV-ACANPAELAGKVDVVITL 59 ++GLG+MG G A S LRAG + D+ + A G A A+ E AG VD ++ L Sbjct: 11 IVGLGSMGMGAARSCLRAGLSTWGADLNPQACANLLAEGACGAAASAREFAGVVDALVIL 70 Query: 60 VVNAAQTETVLFGDNGAVSAMKPGSVVISSATVAPDFAIELGKRLAEKGLLLLDAPVSGG 119 VVNAAQ VLFG++G MKPGS V+ S+T++ A E+ L L +LDAPVSGG Sbjct: 71 VVNAAQVRQVLFGEDGVAHLMKPGSAVMVSSTISSADAQEIAAALTALNLNMLDAPVSGG 130 Query: 120 AARAASGEMTMMTSGPAEVYAKIEDVLAGMAGKVYRLGDTHGIGSKVKIINQLLAGVHIA 179 A +AA GEMT+M SG + +++ VL +A VYR+ DT G GS VKII+QLLAGVHIA Sbjct: 131 AVKAAQGEMTVMASGSEAAFTRLKPVLDAVASNVYRISDTPGAGSTVKIIHQLLAGVHIA 190 Query: 180 ASAEAMALGLREGVNPDALYEVITHSAGNSWMFENRVPHILNGDYTPLSAVDIFVKDLGL 239 A+AEAMAL R G+ D +Y+V+TH+AGNSWMFENR+ H+++GDYTP SAVDIFVKDLGL Sbjct: 191 AAAEAMALAARAGIPLDVMYDVVTHAAGNSWMFENRMQHVVDGDYTPRSAVDIFVKDLGL 250 Query: 240 VLDTARRSKFPLPLSAAAHQMFMMASTAGHGGEDDSAVIKIFPGIDLP 287 V DTA+ +FPLPL++ A MF AS AG+G EDDSAVIKIF GI LP Sbjct: 251 VADTAKALRFPLPLASTALNMFTSASNAGYGKEDDSAVIKIFSGITLP 298 >ygbJ [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Eco Escherichia coli K12 Length = 302 Score = 283 bits (725), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 160/292 (54%), Positives = 204/292 (69%), Gaps = 1/292 (0%) Query: 1 VIGLGAMGYGVASSLLRAGFNVHACDVRKEVLDKFAAAGGVACA-NPAELAGKVDVVITL 59 ++GLG+MG G A S +RAG + D+ AG + N A A K+D ++ L Sbjct: 11 IVGLGSMGMGAALSYVRAGLSTWGADLNSNACATLKEAGACGVSDNAATFAEKLDALLVL 70 Query: 60 VVNAAQTETVLFGDNGAVSAMKPGSVVISSATVAPDFAIELGKRLAEKGLLLLDAPVSGG 119 VVNAAQ + VLFG+ G +KPG+ V+ S+T+A A E+ LA L +LDAPVSGG Sbjct: 71 VVNAAQVKQVLFGETGVAQHLKPGTAVMVSSTIASADAQEIATALAGFDLEMLDAPVSGG 130 Query: 120 AARAASGEMTMMTSGPAEVYAKIEDVLAGMAGKVYRLGDTHGIGSKVKIINQLLAGVHIA 179 A +AA+GEMT+M SG + ++ VL +AGKVYR+G G+GS VKII+QLLAGVHIA Sbjct: 131 AVKAANGEMTVMASGSDIAFERLAPVLEAVAGKVYRIGAEPGLGSTVKIIHQLLAGVHIA 190 Query: 180 ASAEAMALGLREGVNPDALYEVITHSAGNSWMFENRVPHILNGDYTPLSAVDIFVKDLGL 239 A AEAMAL R G+ D +Y+V+T++AGNSWMFENR+ H+++GDYTP SAVDIFVKDLGL Sbjct: 191 AGAEAMALAARAGIPLDVMYDVVTNAAGNSWMFENRMRHVVDGDYTPHSAVDIFVKDLGL 250 Query: 240 VLDTARRSKFPLPLSAAAHQMFMMASTAGHGGEDDSAVIKIFPGIDLPPAKA 291 V DTA+ FPLPL++ A MF AS AG+G EDDSAVIKIF GI LP AK+ Sbjct: 251 VADTAKALHFPLPLASTALNMFTSASNAGYGKEDDSAVIKIFSGITLPGAKS 302 >BMEII1090 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Bme Brucella melitensis Length = 302 Score = 283 bits (723), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 154/291 (52%), Positives = 202/291 (69%) Query: 1 VIGLGAMGYGVASSLLRAGFNVHACDVRKEVLDKFAAAGGVACANPAELAGKVDVVITLV 60 ++GLG+MG GVA S + AG + D+ + AG + ++ E AGK+D ++ LV Sbjct: 12 IVGLGSMGMGVAQSCIAAGLRTYGIDLDPAKCEAIIKAGAIGASSRCEAAGKLDALVLLV 71 Query: 61 VNAAQTETVLFGDNGAVSAMKPGSVVISSATVAPDFAIELGKRLAEKGLLLLDAPVSGGA 120 VNAAQ + VLFG+NG + MKPG+ V+ S+T++ A E+ L LL+LDAPVSGGA Sbjct: 72 VNAAQCKAVLFGENGLAAQMKPGAAVMVSSTISAADAKEIAAALEAYNLLMLDAPVSGGA 131 Query: 121 ARAASGEMTMMTSGPAEVYAKIEDVLAGMAGKVYRLGDTHGIGSKVKIINQLLAGVHIAA 180 A+AASG++T+M SG E + K+ VL AGKVY +G G+G+ VKII+QLLAGVHIAA Sbjct: 132 AKAASGDITVMASGSREAFEKLRPVLNAAAGKVYEIGQEIGLGATVKIIHQLLAGVHIAA 191 Query: 181 SAEAMALGLREGVNPDALYEVITHSAGNSWMFENRVPHILNGDYTPLSAVDIFVKDLGLV 240 AEAMAL R G+ D +Y+V+TH+AGNSWMFENR+ H+++GDYTP SAVDIFVKDL LV Sbjct: 192 GAEAMALAARSGIPLDIMYDVVTHAAGNSWMFENRMKHVVDGDYTPKSAVDIFVKDLRLV 251 Query: 241 LDTARRSKFPLPLSAAAHQMFMMASTAGHGGEDDSAVIKIFPGIDLPPAKA 291 +T FPLPL+ A+ +F AS AG G EDD+AVIK + GI LP A Sbjct: 252 TETGLSMNFPLPLATTAYSLFANASNAGFGKEDDAAVIKTYAGIKLPDRSA 302 >HI1010 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Hin Haemophilus influenzae Length = 301 Score = 275 bits (702), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 156/288 (54%), Positives = 204/288 (70%), Gaps = 1/288 (0%) Query: 1 VIGLGAMGYGVASSLLRAGFNVHACDVRKEVLDKFAAAGGVACA-NPAELAGKVDVVITL 59 VIGLG+MG G A S + AG + D+ L+K AAG A A N + A ++D V+ L Sbjct: 10 VIGLGSMGMGAAVSCINAGLTTYGIDLNPVALEKLKAAGAKAVAANGYDFAHELDAVVIL 69 Query: 60 VVNAAQTETVLFGDNGAVSAMKPGSVVISSATVAPDFAIELGKRLAEKGLLLLDAPVSGG 119 VVNAAQ VLFG+NG +K G+ V+ S+T+A A + ++L E GL++LDAPVSGG Sbjct: 70 VVNAAQANAVLFGENGIAKKLKAGTAVMVSSTMAAQDAQIISQKLTELGLIMLDAPVSGG 129 Query: 120 AARAASGEMTMMTSGPAEVYAKIEDVLAGMAGKVYRLGDTHGIGSKVKIINQLLAGVHIA 179 AA+A GEMT+M SG + + ++ VL A KVY +G+ G+G+ VKI++QLLAGVHIA Sbjct: 130 AAKALKGEMTVMASGSKQAFELLQPVLDATAAKVYNIGEEIGLGATVKIVHQLLAGVHIA 189 Query: 180 ASAEAMALGLREGVNPDALYEVITHSAGNSWMFENRVPHILNGDYTPLSAVDIFVKDLGL 239 A AEAMAL + G+ D +Y+V+T++AGNSWMFENR+ H++ GDYTPLS VDIFVKDLGL Sbjct: 190 AGAEAMALASKAGIPLDVMYDVVTNAAGNSWMFENRMKHVVEGDYTPLSMVDIFVKDLGL 249 Query: 240 VLDTARRSKFPLPLSAAAHQMFMMASTAGHGGEDDSAVIKIFPGIDLP 287 V DTA+ FPL L++ A+ MF AS AG+G EDDSAVIKIF G+ LP Sbjct: 250 VNDTAKSLHFPLHLASTAYSMFTEASNAGYGKEDDSAVIKIFSGVSLP 297 >SMc00274 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Sme Sinorhizobium meliloti Length = 295 Score = 214 bits (545), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 124/280 (44%), Positives = 173/280 (61%), Gaps = 1/280 (0%) Query: 2 IGLGAMGYGVASSLLRAGFNVHACDVRKEVLDKFAAAGGVACANPAELAGKVDVVITLVV 61 +GLG+MG +A +L+RAG V DVR ++ AA GG+ ANPAE DV++ +VV Sbjct: 10 VGLGSMGLPMAENLIRAGHAVRGFDVRAAAMETLAATGGIRSANPAEACSGADVLVLMVV 69 Query: 62 NAAQTETVLFGDNGAVSAMKPGSVVISSATVAPDFAIELGKRLAEKGLLLLDAPVSGGAA 121 NA Q +VL ++GA+S++ G+ + AT PD L + G +L+D PVSGG Sbjct: 70 NAEQARSVLL-ESGALSSLPQGAHICLMATCPPDEVKRLADEVEASGRVLVDCPVSGGVV 128 Query: 122 RAASGEMTMMTSGPAEVYAKIEDVLAGMAGKVYRLGDTHGIGSKVKIINQLLAGVHIAAS 181 A +G +T+M P + Y + VL M KV+ G G G+ VK INQLL GVH+A + Sbjct: 129 GAKAGALTIMVGAPEKAYHAVVPVLQAMGDKVFHCGPEQGQGAVVKAINQLLCGVHLATA 188 Query: 182 AEAMALGLREGVNPDALYEVITHSAGNSWMFENRVPHILNGDYTPLSAVDIFVKDLGLVL 241 AEA+ALG + GV+ L E++++SA +SWM ++R P ++ SAVDIFVKDLG+ L Sbjct: 189 AEALALGEKAGVDAATLLEIVSNSAASSWMLKDRGPRMITKTPPVTSAVDIFVKDLGIAL 248 Query: 242 DTARRSKFPLPLSAAAHQMFMMASTAGHGGEDDSAVIKIF 281 T R LPL+AAAHQMF+ S +G+G EDDS VI + Sbjct: 249 ATGRSVSMALPLAAAAHQMFLAESGSGNGLEDDSQVIAAY 288 >STM3248 [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Sty Salmonella typhimurium LT2 Length = 296 Score = 175 bits (443), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 96/276 (34%), Positives = 158/276 (57%), Gaps = 1/276 (0%) Query: 2 IGLGAMGYGVASSLLRAGFNVHACDVRKEVLDKFAAAGGVACANPAELAGKVDVVITLVV 61 IGLG MG ++ +LL+AG+++ D E + AAG + +A + DV+IT++ Sbjct: 8 IGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETASTAKAIAEQCDVIITMLP 67 Query: 62 NAAQTETVLFGDNGAVSAMKPGSVVISSATVAPDFAIELGKRLAEKGLLLLDAPVSGGAA 121 N+ + V G+NG + KPG+V+I +++AP + E+ L KG+ +LDAPVSGG Sbjct: 68 NSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISDALKAKGVEMLDAPVSGGEP 127 Query: 122 RAASGEMTMMTSGPAEVYAKIEDVLAGMAGKVYRLGDTHGIGSKVKIINQLLAGVHIAAS 181 +A G +++M G ++ K D++ MAG V GD G G+ K+ NQ++ ++IAA Sbjct: 128 KAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGDI-GAGNVTKLANQVIVALNIAAM 186 Query: 182 AEAMALGLREGVNPDALYEVITHSAGNSWMFENRVPHILNGDYTPLSAVDIFVKDLGLVL 241 +EA+ L + GVNPD +Y+ I S + + + P +++ ++ P +D+ +KDL L Sbjct: 187 SEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDLANAL 246 Query: 242 DTARRSKFPLPLSAAAHQMFMMASTAGHGGEDDSAV 277 DT+ LPL+AA +M GHG +D SA+ Sbjct: 247 DTSHGVGAQLPLTAAVMEMMQALRADGHGNDDHSAL 282 >yhaE [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Eco Escherichia coli K12 Length = 299 Score = 167 bits (423), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 94/276 (34%), Positives = 157/276 (56%), Gaps = 1/276 (0%) Query: 2 IGLGAMGYGVASSLLRAGFNVHACDVRKEVLDKFAAAGGVACANPAELAGKVDVVITLVV 61 IGLG MG ++ +LL+AG+++ D E + AAG + +A + DV+IT++ Sbjct: 11 IGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDVIITMLP 70 Query: 62 NAAQTETVLFGDNGAVSAMKPGSVVISSATVAPDFAIELGKRLAEKGLLLLDAPVSGGAA 121 N+ + V G+NG + KPG+V+I +++AP + E+ + L KG+ +LDAPVSGG Sbjct: 71 NSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAPVSGGEP 130 Query: 122 RAASGEMTMMTSGPAEVYAKIEDVLAGMAGKVYRLGDTHGIGSKVKIINQLLAGVHIAAS 181 +A G +++M G ++ K D++ MAG V G+ G G+ K+ NQ++ ++IAA Sbjct: 131 KAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEI-GAGNVTKLANQVIVALNIAAM 189 Query: 182 AEAMALGLREGVNPDALYEVITHSAGNSWMFENRVPHILNGDYTPLSAVDIFVKDLGLVL 241 +EA+ L + GVNPD +Y+ I S + + + P +++ ++ P +D+ +KDL L Sbjct: 190 SEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDLANAL 249 Query: 242 DTARRSKFPLPLSAAAHQMFMMASTAGHGGEDDSAV 277 DT+ LPL+AA +M G G D SA+ Sbjct: 250 DTSHGVGAQLPLTAAVMEMMQALRADGLGTADHSAL 285 >ZyhaE [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases EcZ Escherichia coli O157:H7 EDL933 Length = 299 Score = 167 bits (423), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 94/276 (34%), Positives = 157/276 (56%), Gaps = 1/276 (0%) Query: 2 IGLGAMGYGVASSLLRAGFNVHACDVRKEVLDKFAAAGGVACANPAELAGKVDVVITLVV 61 IGLG MG ++ +LL+AG+++ D E + AAG + +A + DV+IT++ Sbjct: 11 IGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDVIITMLP 70 Query: 62 NAAQTETVLFGDNGAVSAMKPGSVVISSATVAPDFAIELGKRLAEKGLLLLDAPVSGGAA 121 N+ + V G+NG + KPG+V+I +++AP + E+ + L KG+ +LDAPVSGG Sbjct: 71 NSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAPVSGGEP 130 Query: 122 RAASGEMTMMTSGPAEVYAKIEDVLAGMAGKVYRLGDTHGIGSKVKIINQLLAGVHIAAS 181 +A G +++M G ++ K D++ MAG V G+ G G+ K+ NQ++ ++IAA Sbjct: 131 KAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEI-GAGNVTKLANQVIVALNIAAM 189 Query: 182 AEAMALGLREGVNPDALYEVITHSAGNSWMFENRVPHILNGDYTPLSAVDIFVKDLGLVL 241 +EA+ L + GVNPD +Y+ I S + + + P +++ ++ P +D+ +KDL L Sbjct: 190 SEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDLANAL 249 Query: 242 DTARRSKFPLPLSAAAHQMFMMASTAGHGGEDDSAV 277 DT+ LPL+AA +M G G D SA+ Sbjct: 250 DTSHGVGAQLPLTAAVMEMMQALRADGLGTADHSAL 285