BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0244.p (215 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMb20666 [G] COG0235 Ribulose-5-phosphate 4-epimerase and relate... 200 2e-51 ygbL [G] COG0235 Ribulose-5-phosphate 4-epimerase and related ep... 188 6e-48 STM2916 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related... 174 2e-43 BMEII1095 [G] COG0235 Ribulose-5-phosphate 4-epimerase and relat... 174 2e-43 HI1012 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related ... 161 1e-39 YPO1236 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related... 150 2e-36 PM1364 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related ... 148 7e-36 MJ1418 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related ... 98 2e-20 MTH1406 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related... 92 6e-19 PH0191 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related ... 92 1e-18 >SMb20666 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Sme Sinorhizobium meliloti Length = 225 Score = 200 bits (509), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 101/187 (54%), Positives = 130/187 (69%), Gaps = 1/187 (0%) Query: 6 NESALREEICRIGASLYQRGYTVGSAGNISARLEDG-WLITPTDACLGFLDPAAIAKVNA 64 +E+ LREEICR G SL++RG T GS+GNIS RLEDG WL+TPT+A LGFLDPA I++++A Sbjct: 2 SETRLREEICRYGRSLFERGLTPGSSGNISMRLEDGGWLVTPTNASLGFLDPARISRLDA 61 Query: 65 AGEWVSGDKPSKTLVLHRAIYDNNPEMHAVVHTHSTHLVSLTINGVYSEQDVLPPITPYY 124 G VSGDKP+K + LH A+Y+ A+VH HSTH V+LT+ + LPP+TPYY Sbjct: 62 GGRLVSGDKPTKEIPLHSALYETRGSARAIVHLHSTHAVALTMLPEIDARAALPPMTPYY 121 Query: 125 VMKVGHIPLIRYARPGAPEVAEQVAKIATQVRGVLLERLGPVVWESSVSKAAFALEELEE 184 +M+ G L+ Y RPG P VA+ + +A + VLL GPVV S+ A FA EELEE Sbjct: 122 LMRAGETALVPYYRPGDPAVADAIRGLAGRYSSVLLSNHGPVVAGDSLEAAVFATEELEE 181 Query: 185 TAKLWHL 191 TAKL+ L Sbjct: 182 TAKLYLL 188 >ygbL [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Eco Escherichia coli K12 Length = 212 Score = 188 bits (478), Expect = 6e-48, Method: Compositional matrix adjust. Identities = 95/190 (50%), Positives = 127/190 (66%), Gaps = 1/190 (0%) Query: 7 ESALREEICRIGASLYQRGYTVGSAGNISARLEDGWLI-TPTDACLGFLDPAAIAKVNAA 65 E +LREE+ RI +S +QRGY GSAGN+S L DG L+ TPT +CLG LDP ++KV A Sbjct: 8 EQSLREEMTRIASSFFQRGYATGSAGNLSLLLPDGNLLATPTGSCLGNLDPQRLSKVAAD 67 Query: 66 GEWVSGDKPSKTLVLHRAIYDNNPEMHAVVHTHSTHLVSLTINGVYSEQDVLPPITPYYV 125 GEW+SGDKPSK ++ H A+Y NNP AVVH HST +L+ +V+ P TPY V Sbjct: 68 GEWLSGDKPSKEVLFHLALYRNNPRCKAVVHLHSTWSTALSCLQGLDSSNVIRPFTPYVV 127 Query: 126 MKVGHIPLIRYARPGAPEVAEQVAKIATQVRGVLLERLGPVVWESSVSKAAFALEELEET 185 M++G++PL+ Y RPG +A+ +A++A + LL GPVV S+ +AA +EELEET Sbjct: 128 MRMGNVPLVPYYRPGDKRIAQDLAELAADNQAFLLANHGPVVCGESLQEAANNMEELEET 187 Query: 186 AKLWHLAGGR 195 AKL + G R Sbjct: 188 AKLIFILGDR 197 >STM2916 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Sty Salmonella typhimurium LT2 Length = 212 Score = 174 bits (440), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 96/190 (50%), Positives = 124/190 (65%), Gaps = 1/190 (0%) Query: 7 ESALREEICRIGASLYQRGYTVGSAGNISARLEDGWLI-TPTDACLGFLDPAAIAKVNAA 65 E ALREE+ RI AS +QRGY GSAGN+S L DG ++ TPT +CLG LDP ++KV+ Sbjct: 8 EHALREEMVRIAASFFQRGYATGSAGNLSLLLPDGNILATPTGSCLGNLDPQRLSKVDPQ 67 Query: 66 GEWVSGDKPSKTLVLHRAIYDNNPEMHAVVHTHSTHLVSLTINGVYSEQDVLPPITPYYV 125 GEW+SGDKPSK + H A+Y NNP AVVH HST +L+ Q+V+ P TPY V Sbjct: 68 GEWLSGDKPSKEVRFHLALYRNNPCCKAVVHLHSTWSTALSCLEGLDPQNVIRPFTPYVV 127 Query: 126 MKVGHIPLIRYARPGAPEVAEQVAKIATQVRGVLLERLGPVVWESSVSKAAFALEELEET 185 M++G IPL+ Y RPG +A +A +A + + LL GPVV ++ +AA EELEET Sbjct: 128 MRMGDIPLVPYYRPGDDRIARDLAALAARHQAFLLANHGPVVCGENLQEAANNTEELEET 187 Query: 186 AKLWHLAGGR 195 AKL + G R Sbjct: 188 AKLIFILGER 197 >BMEII1095 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Bme Brucella melitensis Length = 224 Score = 174 bits (440), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 95/215 (44%), Positives = 135/215 (62%), Gaps = 6/215 (2%) Query: 2 SRNTNESALREEICRIGASLYQRGYTVGSAGNISARLEDGWLITPTDACLGFLDPAAIAK 61 ++N E +RE I +GASL+ RGY VGSAGNIS RL DG+L+TPT++CLG L ++K Sbjct: 12 TKNMTEQEIRELIVELGASLFARGYCVGSAGNISVRLADGYLMTPTNSCLGRLRADRLSK 71 Query: 62 VNAAGEWVSGDKPSKTLVLHRAIYDNNPEMHAVVHTHSTHLVSLTINGVYSEQDVLP--P 119 ++ + GD+PSK + +HRA+ P+ AVVH HST+ + I+ + S D +P P Sbjct: 72 LDKGWNHIGGDRPSKEVFMHRAVLGARPQAGAVVHLHSTY--ATAISCLSSPADTMPITP 129 Query: 120 ITPYYVMKVG-HIPLIRYARPGAPEVAEQVAKIATQVRGVLLERLGPVVWESSVSKAAFA 178 +TPY+VM++G H+P I Y RPG P + ++ A +LL GPVV +S+ A +A Sbjct: 130 LTPYFVMRIGKHLPTIPYYRPGDPAMEREIHDDAQNASAMLLANHGPVVSGNSLVDAVYA 189 Query: 179 LEELEETAKL-WHLAGGRATPLEEPALEDLRATFK 212 EELEE+A+L L G A L + +EDL TFK Sbjct: 190 AEELEESARLSIMLQGLPARKLTDEQIEDLLHTFK 224 >HI1012 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Hin Haemophilus influenzae Length = 210 Score = 161 bits (407), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 87/201 (43%), Positives = 124/201 (61%), Gaps = 2/201 (0%) Query: 9 ALREEICRIGASLYQRGYTVGSAGNISARLEDGW-LITPTDACLGFLDPAAIAKVNAAGE 67 A +E + ++G S Y+RGYTVG AGN+S RL+D L+TPT + LG L ++ ++ G Sbjct: 5 AQKELMVQLGRSFYERGYTVGGAGNLSVRLDDNRVLVTPTGSSLGRLSVERLSVLDMEGN 64 Query: 68 WVSGDKPSKTLVLHRAIYDNNPEMHAVVHTHSTHLVSLTINGVYSEQDVLPPITPYYVMK 127 + GDKPSK V H A+Y NPE A+VH HST+L +L+ + + P TPYYVM+ Sbjct: 65 LLGGDKPSKEAVFHLAMYKKNPECKAIVHLHSTYLTALSCLDNLDPNNAIEPFTPYYVMR 124 Query: 128 VGHIPLIRYARPGAPEVAEQVAKIATQVRGVLLERLGPVVWESSVSKAAFALEELEETAK 187 VG + +I Y RPG+P++AE+++ A + LL G VV S + AA EELEETAK Sbjct: 125 VGKMQVIPYYRPGSPKIAEELSNRALTGKAFLLANHGVVVTGSDLLDAADNTEELEETAK 184 Query: 188 LWH-LAGGRATPLEEPALEDL 207 L+ L G + L + ++DL Sbjct: 185 LFFTLQGQKIRYLTDTEVKDL 205 >YPO1236 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Ype Yersinia pestis Length = 203 Score = 150 bits (379), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 74/168 (44%), Positives = 107/168 (63%), Gaps = 1/168 (0%) Query: 6 NESALREEICRIGASLYQRGYTVGSAGNISARLEDG-WLITPTDACLGFLDPAAIAKVNA 64 +E +R+++ SL+QRG + G AGNIS +L DG +L+TPT++CLG LD ++K++A Sbjct: 25 SEQQVRDDLVNYARSLFQRGLSSGGAGNISVKLPDGSFLVTPTNSCLGELDSQTLSKLDA 84 Query: 65 AGEWVSGDKPSKTLVLHRAIYDNNPEMHAVVHTHSTHLVSLTINGVYSEQDVLPPITPYY 124 G +SGDKPSK + +H A+Y AVVH HS +L +L+ + LPPITPYY Sbjct: 85 EGNHISGDKPSKEVPMHLAMYRARSTCGAVVHLHSPYLTALSCLTNIDHTNCLPPITPYY 144 Query: 125 VMKVGHIPLIRYARPGAPEVAEQVAKIATQVRGVLLERLGPVVWESSV 172 VM++G +PL+ Y +PG P +A +A A VLL GPVV S++ Sbjct: 145 VMRIGRLPLLSYMKPGDPAIATALADTARDHNAVLLANHGPVVSGSTL 192 >PM1364 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Pmu Pasteurella multocida Length = 210 Score = 148 bits (374), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 76/186 (40%), Positives = 116/186 (62%), Gaps = 1/186 (0%) Query: 11 REEICRIGASLYQRGYTVGSAGNISARLEDG-WLITPTDACLGFLDPAAIAKVNAAGEWV 69 ++E+ + SL++RGY+VG AGN+S RL++ L+TPT + LG L+ +++ ++ G + Sbjct: 7 KKEMVNLARSLFERGYSVGGAGNLSVRLDEKRILVTPTGSSLGRLEADSLSVLDMEGNLL 66 Query: 70 SGDKPSKTLVLHRAIYDNNPEMHAVVHTHSTHLVSLTINGVYSEQDVLPPITPYYVMKVG 129 SG KPSK V H A+Y NP HA+VH HST+L +L+ + + + TPYYVM+VG Sbjct: 67 SGKKPSKESVFHLAMYHQNPACHAIVHLHSTYLTALSCLEGLNPDNAMKAFTPYYVMRVG 126 Query: 130 HIPLIRYARPGAPEVAEQVAKIATQVRGVLLERLGPVVWESSVSKAAFALEELEETAKLW 189 +P+I Y RPG +A ++++ A + LL G VV + + A EELEETAKL+ Sbjct: 127 KLPVIPYYRPGDTNIARELSERALLSKAFLLANHGVVVTGTDLVDAVDNTEELEETAKLY 186 Query: 190 HLAGGR 195 L G+ Sbjct: 187 FLLKGQ 192 >MJ1418 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Mja Methanococcus jannaschii Length = 181 Score = 97.8 bits (242), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 60/181 (33%), Positives = 98/181 (54%), Gaps = 8/181 (4%) Query: 11 REEICRIGASLYQRGYTVGSAGNISARLEDGWLITPTDACLGFLDPAAIAKVNAAGEWVS 70 +++ +I LY R Y VGS GN+S + D +TPT + LGFL IA+++ G + Sbjct: 3 KKQFIKICRKLYDRKYVVGSGGNVSVKEGDKIYLTPTGSILGFLKEDDIAEMDLDGNVIK 62 Query: 71 GDKPSKTLVLHRAIYDNNPEMHAVVHTHSTHLVSLTINGVYSEQDVLPPITPYYVMKVGH 130 G KP+ LH IY +++A++HTHS L+S ++ + E ++L P ++ K+G+ Sbjct: 63 G-KPTSEKNLHLMIYRKRNDINAIIHTHS--LISTFLSTINKEIELLTPEGKIFLKKIGY 119 Query: 131 IPLIRYARPGAPEVAEQVAKIATQVRGVLLERLGPVVWESSVSKAAFALEELEETAKLWH 190 + Y G+ ++AE+ AK V ++L+ G V + A +E LEE AKL Sbjct: 120 VD---YYEAGSLKLAEETAKRDEDV--IILKNHGVVCLGKDLIDAYIKVEVLEEQAKLTL 174 Query: 191 L 191 L Sbjct: 175 L 175 >MTH1406 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Mth Methanothermobacter thermautotrophicus Length = 191 Score = 92.4 bits (228), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 54/180 (30%), Positives = 89/180 (49%), Gaps = 5/180 (2%) Query: 13 EICRIGASLYQRGYTVGSAGNISARLEDGWLITPTDACLGFLDPAAIAKVNAAGEWVSGD 72 E+ + +Y+ G G GN+SAR+ D ITPT LG + + V+ G + G Sbjct: 9 EVVDVSLHIYRTGLVSGIGGNVSARMGDRVFITPTMVPLGEVSLRNVVLVDLNGRVIRGG 68 Query: 73 KPSKTLVLHRAIYDNNPEMHAVVHTHSTHLVSLTINGVYSEQDVLPPITPYYVMKVGHIP 132 +PS L LH +Y P++ +VHTHS H + +I GV E+ + + + G+IP Sbjct: 69 RPSSELGLHLEVYRARPDVGGIVHTHSPHARAFSIAGVQIEK-----MEGFMGLGRGYIP 123 Query: 133 LIRYARPGAPEVAEQVAKIATQVRGVLLERLGPVVWESSVSKAAFALEELEETAKLWHLA 192 ++ Y PG+ E+A + ++ +LE G V + A E +EE+A+ +A Sbjct: 124 MVPYHPPGSRELAAECGRVMVDEDAAILENHGVVCAGEGLRDALLLAEFIEESARTQFIA 183 >PH0191 [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Pho Pyrococcus horikoshii Length = 189 Score = 91.7 bits (226), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 54/167 (32%), Positives = 90/167 (53%), Gaps = 5/167 (2%) Query: 24 RGYTVGSAGNISARLEDGWLITPTDACLGFLDPAAIAKVNAAGEWVSGDKPSKTLVLHRA 83 +G T GNIS R+ + I T + +G L P+ ++ + GE +S KPS LH Sbjct: 18 KGLTGSFGGNISVRVGEYVFIKGTGSVMGELTPSQVSTLTLNGEILSSVKPSSEFRLHLG 77 Query: 84 IYDNNPEMHAVVHTHSTHLVSLTINGVYSEQDVLPPITPYYVMKVGHIPLIRYARPGAPE 143 +Y N ++ AVVH H + ++L+I + LP ITP + + +P++ + G+ E Sbjct: 78 VYRNRADVRAVVHLHPPYSITLSIF-----EKELPMITPEAELYLKKVPVLPFKPAGSVE 132 Query: 144 VAEQVAKIATQVRGVLLERLGPVVWESSVSKAAFALEELEETAKLWH 190 +A+QV++ V+LER G V S+ +A + E +EE A+LW+ Sbjct: 133 LAQQVSEAMKDYDAVILERHGIVTVGRSLREAFYRAELVEEVARLWY 179