BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0243.p (437 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 572 e-163 RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 506 e-143 YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 464 e-130 PA4126 [GEPR] COG0477 Permeases of the major facilitator superfa... 385 e-106 RSp1572 [GEPR] COG0477 Permeases of the major facilitator superf... 358 2e-98 RSp0182 [GEPR] COG0477 Permeases of the major facilitator superf... 350 4e-96 PA2214 [GEPR] COG0477 Permeases of the major facilitator superfa... 341 3e-93 AGc4908 [GEPR] COG0477 Permeases of the major facilitator superf... 327 2e-89 CC2354 [GEPR] COG0477 Permeases of the major facilitator superfa... 312 1e-84 YPO1768 [GEPR] COG0477 Permeases of the major facilitator superf... 307 3e-83 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 572 bits (1474), Expect = e-163, Method: Compositional matrix adjust. Identities = 283/420 (67%), Positives = 341/420 (81%), Gaps = 1/420 (0%) Query: 18 KDGLYKKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMSQDLGFSETVFGLGAGLFFIGYF 77 ++ Y+KV +RI+P LM+CY+IAYLDRVNVGFAKLQMS++LGFSE ++GLGAGLFFIGYF Sbjct: 33 ENMTYRKVAFRIIPLLMICYIIAYLDRVNVGFAKLQMSEELGFSEAIYGLGAGLFFIGYF 92 Query: 78 LFEVPSNILMHKVGARIWIARIMITWGILSAAFMFVQNATQFYILRFLLGLAEAGFYPGI 137 FE+PSNIL+HK+GAR+WIARIMITWG+LSA F FVQ QFYILRFLLG AEAGFYPG+ Sbjct: 93 FFEIPSNILLHKLGARLWIARIMITWGLLSALFAFVQTEWQFYILRFLLGAAEAGFYPGV 152 Query: 138 ILYLTYWFPSHRRAKVIAVFMSGIPVAGILGNPLSGWIMDAFHQNGGLEGWQWMFLIEAI 197 ILYLTYWFPSHRR + A+F +G P AGI GNPLSGWIMD FH G +GWQWMF++EAI Sbjct: 153 ILYLTYWFPSHRRGNMFALFQAGSPAAGIFGNPLSGWIMDQFHDTAGWQGWQWMFVLEAI 212 Query: 198 PAVLIGVATVLYLDNDVKSAKWLNDEEKASLQADIDGDAKGKESKHGFGAIVKDARVWLM 257 PAV++GV +LYLDN VK+AKWL +EEKA + DI+ D+KGK + H ++VK+ +W+M Sbjct: 213 PAVVLGVVILLYLDNSVKAAKWLTEEEKAIISRDIEADSKGKAASHSLMSLVKNPMLWVM 272 Query: 258 CLIYFSFVMGQYGLTLWMPTLVKATGVKGNLEIGLLSAIPFGCAIIAMNLIGRSADRMRE 317 LIYF FVMGQ+GLTLWMPTL++A+GV N+ IGLL AIPF CAIIAM + RSAD RE Sbjct: 273 MLIYFCFVMGQHGLTLWMPTLIRASGVTSNVTIGLLGAIPFICAIIAMVIFSRSADHYRE 332 Query: 318 RRWHLVIPALMGGVGFVGAALFADNTAVSIASLSLAAAGVLTCAPLFWSLPTAFLSGAAA 377 RRWHLV+PAL+G VGFV AA A NT VSI LS+AAAGVL CAPLFWSLPTA LSGAAA Sbjct: 333 RRWHLVVPALLGAVGFVVAAS-ATNTTVSIIFLSMAAAGVLACAPLFWSLPTAILSGAAA 391 Query: 378 AVGIAAINSVGNLAGFVSPYLIGYLKDLTHNNATGMYMLAVMLVVGSIATLATKPGMVNK 437 A GIA INSV NLAGF+SPY++G ++D TH++ GMY+LA L++G+ L VN+ Sbjct: 392 AAGIALINSVANLAGFISPYMVGIIRDATHSSELGMYVLAGFLILGAAIVLCIPASKVNR 451 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 506 bits (1302), Expect = e-143, Method: Compositional matrix adjust. Identities = 249/420 (59%), Positives = 324/420 (77%), Gaps = 1/420 (0%) Query: 18 KDGLYKKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMSQDLGFSETVFGLGAGLFFIGYF 77 ++ Y+KV WR++PFL+LCYV+AYLDRVNVGFAKLQM DL FSETV+GLGAG+FFIGYF Sbjct: 24 EEATYRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFSETVYGLGAGIFFIGYF 83 Query: 78 LFEVPSNILMHKVGARIWIARIMITWGILSAAFMFVQNATQFYILRFLLGLAEAGFYPGI 137 LFEVPSN+++H+VGAR+WIARIMI+WG++SAA MFV FY++RFLLGLAEAGF+PGI Sbjct: 84 LFEVPSNVILHRVGARMWIARIMISWGLISAAMMFVTTPAMFYVMRFLLGLAEAGFFPGI 143 Query: 138 ILYLTYWFPSHRRAKVIAVFMSGIPVAGILGNPLSGWIMDAFHQNGGLEGWQWMFLIEAI 197 ILYLTYW+P+ RR + FM+ + ++G++G P+SGW + F GL GWQWMFLIE I Sbjct: 144 ILYLTYWYPAERRGRTTTFFMTAVALSGVIGGPISGWALKTFGGVYGLAGWQWMFLIEGI 203 Query: 198 PAVLIGVATVLYLDNDVKSAKWLNDEEKASLQADIDGDAKGKESKHGFGAIVKDARVWLM 257 P+V+IG+ + YLDN + A+WL DEEKA L +I + KE AI+ RVWLM Sbjct: 204 PSVVIGLCVLAYLDNRISHARWLTDEEKALLTRNIAAEEAQKEDAP-IAAIMASPRVWLM 262 Query: 258 CLIYFSFVMGQYGLTLWMPTLVKATGVKGNLEIGLLSAIPFGCAIIAMNLIGRSADRMRE 317 LIYFSFVMG YG++ W+PTL+K TGV L +GLL+AIP+G A++AM L+ RSADR RE Sbjct: 263 SLIYFSFVMGLYGVSFWLPTLIKQTGVADPLSVGLLTAIPYGAAVVAMVLVARSADRTRE 322 Query: 318 RRWHLVIPALMGGVGFVGAALFADNTAVSIASLSLAAAGVLTCAPLFWSLPTAFLSGAAA 377 RRWH+ IPAL G +G V +A++ NT +++A+L+L G+LT PLFWSLPTAFL+G A Sbjct: 323 RRWHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLGTMGILTTLPLFWSLPTAFLAGTGA 382 Query: 378 AVGIAAINSVGNLAGFVSPYLIGYLKDLTHNNATGMYMLAVMLVVGSIATLATKPGMVNK 437 A GIA INS+GNLAGF+SPY +G+LKD T + +GMY+LA +V+G++ TL+ VN+ Sbjct: 383 AAGIALINSLGNLAGFLSPYAVGWLKDTTRSTDSGMYLLAASMVLGALLTLSVPARTVNR 442 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 464 bits (1195), Expect = e-130, Method: Compositional matrix adjust. Identities = 228/441 (51%), Positives = 311/441 (70%), Gaps = 9/441 (2%) Query: 1 MTTASTTGVCLDVNDKSKDGLYKKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMSQDLGF 60 M+ +ST + + ++ Y+K W ++P LMLCYV+ YLDRVNVGFAKLQM+ DL F Sbjct: 1 MSESSTESLSQPTQLQEENNAYRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDLQF 60 Query: 61 SETVFGLGAGLFFIGYFLFEVPSNILMHKVGARIWIARIMITWGILSAAFMFVQNATQFY 120 S+TV+GLGAG+FFIGYF E+PSN+++H+VGAR+WIARIMITWGI+SA FV FY Sbjct: 61 SDTVYGLGAGMFFIGYFFLEIPSNLILHRVGARLWIARIMITWGIISACMAFVTTPMSFY 120 Query: 121 ILRFLLGLAEAGFYPGIILYLTYWFPSHRRAKVIAVFMSGIPVAGILGNPLSGWIMDAFH 180 ++RFLLG+AEAGF+PGIILY++YWFPSHRR +V +F+ +P++GI+G PLSGWIM F+ Sbjct: 121 VMRFLLGVAEAGFFPGIILYISYWFPSHRRGRVYGLFVISVPLSGIIGAPLSGWIMQYFN 180 Query: 181 QNGGLEGWQWMFLIEAIPAVLIGVATVLYLDNDVKSAKWLNDEEKASLQADIDGDAKGKE 240 G GWQWMF++E IP+VL+G+ + L + + A WL D+EK LQ +I+ E Sbjct: 181 GFQGYAGWQWMFILEGIPSVLVGILIIYKLKDRITHATWLTDKEKDILQTNIE-----NE 235 Query: 241 SKHGFGAIVKDA----RVWLMCLIYFSFVMGQYGLTLWMPTLVKATGVKGNLEIGLLSAI 296 + H + ++DA RVWL+ LIYF + G Y + W+PTL++ +GVK L IG L+AI Sbjct: 236 AAHYAHSRLRDAFLQPRVWLLTLIYFCLISGFYTIGFWLPTLIRDSGVKDILSIGFLTAI 295 Query: 297 PFGCAIIAMNLIGRSADRMRERRWHLVIPALMGGVGFVGAALFADNTAVSIASLSLAAAG 356 P A + M ++ RSADR+RERRWHL + A++G VG + + F+DN V++ L++ A G Sbjct: 296 PSAAAAVTMIVVSRSADRLRERRWHLALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAMG 355 Query: 357 VLTCAPLFWSLPTAFLSGAAAAVGIAAINSVGNLAGFVSPYLIGYLKDLTHNNATGMYML 416 L+ PLFWSLPTAFL G+AAA GIA INS GNL GFV+PY++GYLKDLT + TGM ++ Sbjct: 356 ALSTIPLFWSLPTAFLGGSAAAAGIAFINSWGNLGGFVAPYMMGYLKDLTQSTTTGMLII 415 Query: 417 AVMLVVGSIATLATKPGMVNK 437 + L +G+ VN Sbjct: 416 STTLFIGAALVFLIPAKAVNH 436 >PA4126 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 434 Score = 385 bits (988), Expect = e-106, Method: Compositional matrix adjust. Identities = 206/440 (46%), Positives = 296/440 (67%), Gaps = 10/440 (2%) Query: 1 MTTAST-TGVCLDVNDKSKDGLYKKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMSQDLG 59 M+TAST L ++D + D +V WR+MP L++CYV A+LDR+N+GFAKLQMS DL Sbjct: 1 MSTASTLNSTTLPLSDSTHD----RVTWRLMPLLLVCYVFAHLDRINIGFAKLQMSADLH 56 Query: 60 FSETVFGLGAGLFFIGYFLFEVPSNILMHKVGARIWIARIMITWGILSAAFMFVQNATQF 119 FS+TV+GLGAGLFFI Y LF +PSN+++ ++G R WIA +M+ WG LS A + V+ A F Sbjct: 57 FSDTVYGLGAGLFFIAYALFGLPSNLMLERIGPRRWIACLMLVWGCLSTAMLLVETARGF 116 Query: 120 YILRFLLGLAEAGFYPGIILYLTYWFPSHRRAKVIAVFMSGIPVAGILGNPLSGWIMDAF 179 Y+LRFLLG+AEAGF+PGI++YL WFP+ RR ++ A+F +P+AG++G PLSGWI++ F Sbjct: 117 YLLRFLLGVAEAGFFPGILVYLNRWFPARRRGQITALFAIAVPMAGVIGGPLSGWILEGF 176 Query: 180 HQNGGLEGWQWMFLIEAIPAVLIGVATVLYLDNDVKSAKWLNDEEKASLQADIDGDAKGK 239 H GL GWQWMFLIE +P VL+GV L + WL+DE+K L+ ++ G+ + + Sbjct: 177 HDALGLRGWQWMFLIEGLPVVLLGVVVWCSLPESFERVTWLSDEQKHLLREELAGEEQ-R 235 Query: 240 ESKHGFGAIVKDARVWLMCLIYFSFVMGQYGLTLWMPTLVKATGVKGNLEIGLLSAIPF- 298 ++ F I + +VWL+ IYF+ ++ + WMP+L+ G+ + IG+LSA+P+ Sbjct: 236 KTITSFSGIFSNPQVWLLVAIYFAVMLAVNTIAFWMPSLIHGAGIAQDSRIGMLSAVPYL 295 Query: 299 -GCAIIAMNLIGRSADRMRERRWHLVIPALMGGVGFVGAALFADNTAVSIASLSLAAAGV 357 GCA M IGRS+DR+RERRWHL IP LM G AAL + + + L +A G Sbjct: 296 AGCAF--MIFIGRSSDRLRERRWHLGIPLLMAAAGLSLAALAPTSAWLVMGGLVIAGMGA 353 Query: 358 LTCAPLFWSLPTAFLSGAAAAVGIAAINSVGNLAGFVSPYLIGYLKDLTHNNATGMYMLA 417 P+FW LP AFLS A A GIA I+S G++A F++PYLIG+++D T + + +Y+LA Sbjct: 354 SAALPMFWQLPPAFLSSATLAAGIALISSFGSIAAFLAPYLIGWMRDTTQSASLALYLLA 413 Query: 418 VMLVVGSIATLATKPGMVNK 437 +++ +G+ L T +VN Sbjct: 414 ILIALGAGLVLRTPAAVVNP 433 >RSp1572 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 358 bits (918), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 180/399 (45%), Positives = 255/399 (63%), Gaps = 3/399 (0%) Query: 14 NDKSKDGLYKKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMSQDLGFSETVFGLGAGLFF 73 + + +Y V RI+PFL CY+ AYLDR+N+GFAKLQM DL S+ +GLGAG+FF Sbjct: 12 SGERSTSVYSVVNRRILPFLATCYLFAYLDRINIGFAKLQMQNDLALSDAAYGLGAGIFF 71 Query: 74 IGYFLFEVPSNILMHKVGARIWIARIMITWGILSAAFMFVQNATQFYILRFLLGLAEAGF 133 GY LFEVPSN+L+ K+GAR ++RI+I WGI+SA+ +FV + FY LRFLLG+ EAGF Sbjct: 72 FGYMLFEVPSNLLLVKIGARRTLSRILILWGIVSASMLFVTDVWTFYALRFLLGVFEAGF 131 Query: 134 YPGIILYLTYWFPSHRRAKVIAVFMSGIPVAGILGNPLSGWIMDAFHQNGGLEGWQWMFL 193 PG+I YLT W+P R A+ +AV + P+ G++G P S WIM F GGL GWQWMFL Sbjct: 132 APGMIYYLTQWYPGERMARAMAVVLGAAPLGGVIGGPASTWIMGHFAGAGGLAGWQWMFL 191 Query: 194 IEAIPAVLIGVATVLYLDNDVKSAKWLNDEEKASLQADIDGDAKGKESKHGFGAIVKDAR 253 E IP++L+G+A YL + A+WL D +KA + DI A G+ S FG + + + Sbjct: 192 AEGIPSILLGIAAYGYLVDKPADARWLTDAQKAVIAGDIARAAPGQASS--FGKALTEPK 249 Query: 254 VWLMCLIYFSFVMGQYGLTLWMPTLVKATGVKGNLEIGLLSAIPFGCAIIAMNLIGRSAD 313 ++++ YF + G Y + W+P+++K+ G+ +IGL SAIP I+AM +GR +D Sbjct: 250 LYVLAAAYFCLICGVYAVGFWLPSILKSAGLSDLFQIGLYSAIPNLAMIVAMYALGRRSD 309 Query: 314 RMRERRWHLVIPALMGGVGFVGAALFADNTAVSIASLSLAAAGVLTCAPLFWSLPTAFLS 373 R ER H I A++ G G + A +A + ++ S++LA+A + +FW++P L Sbjct: 310 RRGERHLHSAITAVL-GAGLLAWAAYATSFPAALISITLASAAIFASYSVFWAIPQQHLK 368 Query: 374 GAAAAVGIAAINSVGNLAGFVSPYLIGYLKDLTHNNATG 412 G AAA GIA INS+G GF SP LIG+ K+ T + G Sbjct: 369 GTAAAGGIALINSIGLFGGFFSPTLIGWTKEATGSLQAG 407 >RSp0182 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 453 Score = 350 bits (898), Expect = 4e-96, Method: Compositional matrix adjust. Identities = 184/417 (44%), Positives = 265/417 (63%), Gaps = 5/417 (1%) Query: 18 KDGLYKKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMSQDLGFSETVFGLGAGLFFIGYF 77 + + +K+ WRI+PF+ Y+I+YLDR N+G+A LQM+Q+L S FG +G+FFIGYF Sbjct: 26 ERAIVRKITWRILPFVFALYIISYLDRANIGYAALQMNQELALSSEAFGFVSGIFFIGYF 85 Query: 78 LFEVPSNILMHKVGARIWIARIMITWGILSAAFMFVQNATQFYILRFLLGLAEAGFYPGI 137 LFEVPSN+++++ GAR WIARI++TWG+++ FVQ+ATQ Y LRFLLG+AEAGF+PGI Sbjct: 86 LFEVPSNLMLNRFGARRWIARILVTWGLVAMGSAFVQSATQLYALRFLLGVAEAGFFPGI 145 Query: 138 ILYLTYWFPSHRRAKVIAVFMSGIPVAGILGNPLSGWIMDAFHQNGGLEGWQWMFLIEAI 197 I+YLTYWF + A +A+F + IPV+ ++G PLS WIMD H GW+WM L+E Sbjct: 146 IVYLTYWFRARELATTVALFTAAIPVSYVVGAPLSTWIMDHVHWL-QWSGWRWMLLLEGA 204 Query: 198 PAVLIGVATVLYLDNDVKSAKWLNDEEKASLQADIDGDAKGKESKHGFGA--IVKDARVW 255 PAV+ G+ YL + K A+WL++ E+ L A+++ D K + + ++ RV Sbjct: 205 PAVIGGLLCYGYLADRPKDARWLSEAERDWLLAELERDRKARPAAAHLATLKVMTHPRVL 264 Query: 256 LMCLIYFSFVMGQYGLTLWMPTLVKA-TGVKGNLEIGLLSAIPFGCAIIAMNLIGRSADR 314 + IYF + G G+ WMP ++K + + E+GL++ +P+ A M R +D Sbjct: 265 YLAFIYFVYQCGSLGIGYWMPQIIKGFSSALSHTEVGLIAMLPYVFATAVMIWWSRRSDL 324 Query: 315 MRERRWHLVIPALMGGVGFVGAALFADNTAVSIASLSLAAAGVLTCAPLFWSLPTAFLSG 374 ERR H +P + + FVGA F + AV++A LSL+ AG+ FW+LPT FL+ Sbjct: 325 RAERRLHSAVPLGVAALAFVGAG-FIGHPAVAMAMLSLSLAGLYAFKSPFWALPTLFLTR 383 Query: 375 AAAAVGIAAINSVGNLAGFVSPYLIGYLKDLTHNNATGMYMLAVMLVVGSIATLATK 431 + AAV IA INSVGNL GFV P+ IGY K H+ G+ LA +L V + TL + Sbjct: 384 STAAVSIAVINSVGNLGGFVGPFAIGYFKGQMHSTTAGLLFLAGLLAVSFVMTLRLR 440 >PA2214 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 440 Score = 341 bits (874), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 181/410 (44%), Positives = 275/410 (67%), Gaps = 9/410 (2%) Query: 28 RIMPFLMLCYVIAYLDRVNVGFAKLQMSQDLGFSETVFGLGAGLFFIGYFLFEVPSNILM 87 R++PFL+L YV+A++DR NVG+A+ + D G + F GA +FFIGY FEVPSN+++ Sbjct: 21 RLLPFLVLMYVLAFIDRANVGYARAFLQADTGLGDAAFAFGASIFFIGYACFEVPSNLML 80 Query: 88 HKVGARIWIARIMITWGILSAAFMFVQNATQFYILRFLLGLAEAGFYPGIILYLTYWFPS 147 H++GAR+W+ RIM+TWG++SAA MF +A FY+LRFLLG+AEAGF+PGIILYLTYWFP Sbjct: 81 HRLGARVWLCRIMVTWGLVSAAMMFADDAMTFYVLRFLLGVAEAGFFPGIILYLTYWFPQ 140 Query: 148 HRRAKVIAVFMSGIPVAGILGNPLSGWIMDAFHQNGGLEGWQWMFLIEAIPAVLIGVATV 207 RA+ + +F G+P+A +LG PLSGW+++ FH GL WQW+F+ E + A L+G+A Sbjct: 141 RSRAQALGLFYFGLPLALVLGGPLSGWLLE-FHGIFGLANWQWLFVTEGLLASLVGIAAY 199 Query: 208 LYLDNDVKSAKWLNDEEKASLQADIDGDAKGKESK--HGFGAIVKDARVWLMCLIYFSFV 265 YL + + A WL+DE+K +L+ ++ + K+++ HGF + ++ +V CL+YF+ Sbjct: 200 FYLVDRPRDAGWLSDEQKRALEGELAEEDTRKQARGPHGFLSALRSGQVLKFCLVYFTIQ 259 Query: 266 MGQYGLTLWMPTLVKATGVKGN--LEIGLLSAIPFGCAIIAMNLIGRSADRMRERRWHLV 323 M YG+ ++PT + A+ + G L +GL++AIP+ CA++ L+ R ADR + R L Sbjct: 260 MSVYGVVFYLPTRI-ASFLDGQVGLNVGLITAIPWVCALVVTRLVTRQADRSGQHR-QLA 317 Query: 324 IPALMGGVGFVGAALFADNTAVSIASLSLAAAGVLTCAPLFWSLPTAFLSGAAAAVGIAA 383 + L + A+ A N +++ + AA+G ++ PLFW+LPT +LSGAAAA GIA Sbjct: 318 VAMLGMAAAGIAASALAGNLGLAVIAFCFAASGFVSVQPLFWTLPTGYLSGAAAASGIAL 377 Query: 384 INSVGNLAGFVSPYLIGYLKDLTHNNATGMYMLAVMLVVGS--IATLATK 431 INS+GNL GFV+P L ++ + GM+ LA + ++G+ +A L T Sbjct: 378 INSLGNLGGFVAPNLKTLMESQFADPRAGMFALAAVGLLGACLLARLKTS 427 >AGc4908 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 487 Score = 327 bits (839), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 187/423 (44%), Positives = 265/423 (62%), Gaps = 6/423 (1%) Query: 17 SKDGLYKKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMSQDLGFSETVFGLGAGLFFIGY 76 S+ L K+ WR+MPFL L Y+IAY+DR NV +AKLQM L SE +GLGA LFFIGY Sbjct: 65 SEKALISKITWRLMPFLGLLYLIAYIDRQNVSYAKLQMVDALSLSEYAYGLGASLFFIGY 124 Query: 77 FLFEVPSNILMHKVGARIWIARIMITWGILSAAFMFVQNATQFYILRFLLGLAEAGFYPG 136 FLFEVPSN+ +++ GA W ARI+++WG ++ A + QNAT FYILRFLLGL EAGF+PG Sbjct: 125 FLFEVPSNLFLNRFGASKWFARILVSWGAVTIALAYTQNATMFYILRFLLGLCEAGFFPG 184 Query: 137 IILYLTYWFPSHRRAKVIAVFMSGIPVAGILGNPLSGWIMDAFHQNGGLEGWQWMFLIEA 196 ++ +T WFP R ++I +FM +A +G PL G ++D G GW+W+FL Sbjct: 185 VLFLMTLWFPRDYRGRMIGLFMIFSALANAVGAPLGGMLLD-LDGFLGYAGWEWVFLATG 243 Query: 197 IPAVLIGVATVLYLDNDVKSAKWLNDEEKASLQADIDGDAKGKE--SKHGFGAIVKDARV 254 IPAV+ G+ T YLD+ AK+L +EK L+ + + KG E ++ GF A+V + RV Sbjct: 244 IPAVIAGIVTFFYLDDTPDKAKFLTQDEKDWLKNRLAEENKGMEEHAEDGFKALV-NPRV 302 Query: 255 WLMCLIYFSFVMGQYGLTLWMPTLVKATGVKGNLEIGLLSAIPFGCAIIAMNLIGRSADR 314 M L Y F + YGL+ W+PT+VK+ GV N G ++ IP+ IA+ ++ +AD+ Sbjct: 303 LFMALCYVGFPLAAYGLSYWLPTIVKSFGVS-NTTNGFINIIPWIIVAIALFVVPSAADK 361 Query: 315 MRERRWHLVIPALMGGVGFVGAALFADNTAVSIASLSLAAAGVLTCAPLFWSLPTAFLSG 374 + + ++V PA +G + +AL +D + A L +AAAG+ P+FWSLP FL G Sbjct: 362 AKNKTPYIVGPAFVGAFCLLMSALLSD-PVLQFAFLCVAAAGIFAGQPVFWSLPGRFLKG 420 Query: 375 AAAAVGIAAINSVGNLAGFVSPYLIGYLKDLTHNNATGMYMLAVMLVVGSIATLATKPGM 434 A AA GIAAINSVGNL GFV+ ++ ++KD T + M+ LA L + + + M Sbjct: 421 AGAAAGIAAINSVGNLGGFVAQNVVPWIKDQTGSTIAPMFFLAFCLALAGVLVIIATRKM 480 Query: 435 VNK 437 N+ Sbjct: 481 GNQ 483 >CC2354 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 430 Score = 312 bits (799), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 168/417 (40%), Positives = 246/417 (58%), Gaps = 8/417 (1%) Query: 12 DVNDKSKDGLYKKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMSQDLGFSETVFGLGAGL 71 D + + +V R+MP L Y+IAY+DR NV +AKL M LG SE +GLGA L Sbjct: 3 DPSSALERATVGRVTRRLMPLFCLMYLIAYIDRQNVSYAKLDMVSALGLSEAAYGLGASL 62 Query: 72 FFIGYFLFEVPSNILMHKVGARIWIARIMITWGILSAAFMFVQNATQFYILRFLLGLAEA 131 FFIGYFLFE P+N+++ +VGAR+W ARIM +WG+++ A F QNA FY+LRFLLG+AEA Sbjct: 63 FFIGYFLFEAPANLILARVGARVWFARIMFSWGLVTLALGFTQNAAMFYVLRFLLGVAEA 122 Query: 132 GFYPGIILYLTYWFPSHRRAKVIAVFMSGIPVAGILGNPLSGWI--MDAFHQNGGLEGWQ 189 GF+PG++ LT W+P RA+++ +FM A +G + G + MD F GL GWQ Sbjct: 123 GFFPGVLYVLTLWYPQAHRARMVGLFMIASAFANAVGAAIGGLLLGMDGFL---GLAGWQ 179 Query: 190 WMFLIEAIPAVLIGVATVLYLDNDVKSAKWLNDEEKASLQADIDGDAKGKESKH-GFGAI 248 W+FL+ PAVL+ + L + A+WL D EK+ L + + + G+ H G Sbjct: 180 WVFLVTGAPAVLLAPYVLWRLPSGPSDARWLPDVEKSWLASTLAAERGGEVDDHRGAWKA 239 Query: 249 VKDARVWLMCLIYFSFVMGQYGLTLWMPTLVKATGVKGNLEIGLLSAIPFGCAIIAMNLI 308 + D RV ++ +Y + YGL+ W+PT+VK+ GV + G ++ IP+ +A+ + Sbjct: 240 IFDPRVLMLAGLYIGMPLSAYGLSYWLPTIVKSFGVSNTVN-GFINVIPWLLVAVALWFV 298 Query: 309 GRSADRMRERRWHLVIPALMGGVGFVGAALFADNTAVSIASLSLAAAGVLTCAPLFWSLP 368 R A R WH+ P L+ V + ++ A+ L +AA + P+FWSLP Sbjct: 299 PRHAARHGASAWHIAGPVLLAAVA-LSLSVILPGAALKFTMLCIAAPAIFAAQPVFWSLP 357 Query: 369 TAFLSGAAAAVGIAAINSVGNLAGFVSPYLIGYLKDLTHNNATGMYMLAVMLVVGSI 425 +FLSG AA GIA IN+VGNL GF++ L+ ++D T + M LA +L+V S+ Sbjct: 358 PSFLSGPRAAAGIATINAVGNLGGFIAQNLVPVVRDATGSELAPMLALAAVLLVTSL 414 >YPO1768 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 455 Score = 307 bits (787), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 176/438 (40%), Positives = 260/438 (59%), Gaps = 20/438 (4%) Query: 4 ASTTGVCLDVNDKS-----KDGLYKKVFWRIMPFLMLCYVIAYLDRVNVGFAKLQMSQDL 58 ++ GV VN + + + K+F R++PFL L +V A+LDR+N+GFA L M +DL Sbjct: 6 STAPGVTPPVNKNTPLSAQQQSVINKLFRRLIPFLFLLFVFAFLDRINIGFAGLTMGKDL 65 Query: 59 GFSETVFGLGAGLFFIGYFLFEVPSNILMHKVGARIWIARIMITWGILSAAFMFVQNATQ 118 G S T FGL LF++ Y LF +PSNI++ VGAR WIA IM+ WGI S A +F Sbjct: 66 GLSATTFGLATTLFYVTYILFAIPSNIMLGIVGARRWIATIMVLWGIASTATLFAVGPNS 125 Query: 119 FYILRFLLGLAEAGFYPGIILYLTYWFPSHRRAKVIAVFMSGIPVAGILGNPLSGWI--M 176 Y+LR ++G+ EAGF PGI++YLTYWFP+H RA+ A+FM +PV LG+ +SG+I + Sbjct: 126 LYLLRMIVGITEAGFLPGILVYLTYWFPAHFRARANALFMVAMPVTMALGSLVSGYILAL 185 Query: 177 DAFHQNGGLEGWQWMFLIEAIPAVLIGVATVLYLDNDVKSAKWLNDEEKASLQADIDGDA 236 D F + GWQW+FL+E P+VL+G YLD+ + A+WL E+K LQ ++ D Sbjct: 186 DGFLN---MRGWQWLFLLEGFPSVLLGGVVWFYLDDTPQKARWLTKEDKQCLQEMLESDR 242 Query: 237 KGKESKHGFGAIVKDAR--------VWLMCLIYFSFVMGQYGLTLWMPTLVKA-TGVKGN 287 + +GA+ + A V + L YF + +W P ++++ N Sbjct: 243 LQLAKQADYGALPQSAMWREIFTPVVLMYTLAYFCLTNTLSAVNIWTPQILQSFNQSSSN 302 Query: 288 LEIGLLSAIPFGCAIIAMNLIGRSADRMRERRWHLVIPALMGGVGFVGAALFADNTAVSI 347 + IGLL+AIP C I M R +DR++ER+ H V+P L G+V A+ N+ + + Sbjct: 303 ITIGLLAAIPQVCTIAGMIWWSRRSDRVQERKMHTVLPYLFAAAGWVLASA-TQNSVIQL 361 Query: 348 ASLSLAAAGVLTCAPLFWSLPTAFLSGAAAAVGIAAINSVGNLAGFVSPYLIGYLKDLTH 407 + +A+ G T +FW+ P +S A AVGIA IN+ GN+ VSP LIG+LKD T Sbjct: 362 LGIIMASTGSFTAMAIFWTTPDQSISLRARAVGIAVINATGNIGSAVSPVLIGWLKDQTG 421 Query: 408 NNATGMYMLAVMLVVGSI 425 N +G+Y +A +LV+G++ Sbjct: 422 NFNSGLYFVAGLLVIGAV 439