BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0185.p (403 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2228 [V] COG1680 Beta-lactamase class C and other penicillin b... 163 5e-40 PA5542 [V] COG1680 Beta-lactamase class C and other penicillin b... 140 7e-33 PA4347 [V] COG1680 Beta-lactamase class C and other penicillin b... 119 1e-26 Rv1723 [V] COG1680 Beta-lactamase class C and other penicillin b... 117 7e-26 MT1764 [V] COG1680 Beta-lactamase class C and other penicillin b... 117 7e-26 mll2884 [V] COG1680 Beta-lactamase class C and other penicillin ... 116 9e-26 RSc1765 [V] COG1680 Beta-lactamase class C and other penicillin ... 109 1e-23 mll2882 [V] COG1680 Beta-lactamase class C and other penicillin ... 105 2e-22 AGc1692 [V] COG1680 Beta-lactamase class C and other penicillin ... 100 5e-21 BMEII0318 [V] COG1680 Beta-lactamase class C and other penicilli... 91 7e-18 >PA2228 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Pae Pseudomonas aeruginosa Length = 403 Score = 163 bits (413), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 131/359 (36%), Positives = 187/359 (52%), Gaps = 27/359 (7%) Query: 54 KVFEANRIARSTHPRPWPMALRALEISVPWKDGSQLPVIDFLKTTSAHAFVVIQDGKIVY 113 ++F + I +S + LR + S ++ G ++ D+L +++ +V+ D +I + Sbjct: 50 RLFNSVPIKKSGAAHFFEKNLRDMPGSFSFQ-GHEIGFKDWLASSNTTGLIVLSDDRIAF 108 Query: 114 ERYIDGYDANSRFTSFSVAKSFVSALTGVALQQGKIRSLDEPIGHYLNSDEIAPAYAGIT 173 E Y G A S +S++KS +S L G+A+ +G I SL +P+ Y A YAG++ Sbjct: 109 EEYYLGNSAKSLAIGWSLSKSLMSLLIGMAVDEGSIHSLLDPVNLYAPQLS-AGGYAGVS 167 Query: 174 IGQLLDMRSGIDVDENYGGSLASPVVRMFVSTDLHRFIARR-SGLRF--APGSRFEYRSV 230 + +L+M SGI E+YG S S + ++ + L + + S LR APG Y SV Sbjct: 168 LRDVLEMSSGIAFSEDYGNS-DSDINQLGRTIALGGSVNEKVSSLRREDAPGRVHHYVSV 226 Query: 231 DTLVLSRVLAHATGMRLSDFAQQVLWEPLGMEQDASWSVDSGQHGVEKAFCCLNTTARDF 290 DT VL VL ATGM S F Q LW LG E + +W D G E AF +N RDF Sbjct: 227 DTQVLGMVLLGATGMGPSQFMNQRLWPQLGAECEGAWLTD--DRGTELAFGGVNLCLRDF 284 Query: 291 ARLGLLYLDGGR-VGDQQVVSPSWAHEPRQP----------VNHGE-VLDYRDGWWIPPG 338 AR+GLL+L GGR + Q+VS W +P + GE L Y WWIP G Sbjct: 285 ARIGLLFLHGGRSLTGSQIVSAEWVKASTKPRSAHLRPGRYIEDGEPNLGYGYQWWIPEG 344 Query: 339 NADDRDFSAIGVFGQYIYVNPATRTVIVKLS---DYGVE--QDEVLTMLAMRSISHYVA 392 + +F AIGV+GQ+IYVNP R VI K S DY V+ + E + A R+IS V Sbjct: 345 K--EGEFLAIGVYGQFIYVNPLRRVVIAKTSAYVDYNVDGIRMEHEALAAFRAISRTVG 401 >PA5542 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Pae Pseudomonas aeruginosa Length = 414 Score = 140 bits (352), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 107/346 (30%), Positives = 167/346 (48%), Gaps = 40/346 (11%) Query: 54 KVFEANRIARSTHPRPWPMALRALEISVPWK-DGSQLPVIDFLKTTSAHAFVVIQDGKIV 112 KV+ I + T RP P + I+ ++ G + V DF++ ++++DGK+ Sbjct: 57 KVYPTRVIHKGTKVRPLPAGV---AIAPRYRIGGEEYGVDDFMRRNRVGGVLILKDGKVA 113 Query: 113 YERYIDGYDANSRFTSFSVAKSFVSALTGVALQQGKIRSLDEPIGHYLNSDEIAPAYAGI 172 ERY G D +R+TSFSV KS S L G A+QQG + +LD+P+ YL S AY G+ Sbjct: 114 LERYGLGNDERTRWTSFSVVKSISSTLVGAAVQQGLL-ALDQPVDKYLPS-LAGSAYQGV 171 Query: 173 TIGQLLDMRSGIDVDENYGGSLASPVVRMFVSTDLHRFIARRSG----------LRFAPG 222 T+ Q+L M SG+ +E Y S +MF + +A R G ++ G Sbjct: 172 TVEQVLQMSSGVRWNETYRDP-KSDRRQMFDAQ-----LAERPGGILRLLASLPRQYPSG 225 Query: 223 SRFEYRSVDTLVLSRVLAHATGMRLSDFAQQVLWEPLGMEQDASWSVDSGQHGVEKAFCC 282 + F Y + ++ + S +L AT + +SD+ + +W +GME D W ++S G E Sbjct: 226 THFTYSTGESHLQSELLHAATRIPVSDYLSERIWARMGMESDGFWQLES-PAGQEIGSSG 284 Query: 283 LNTTARDFARLGLLYLDGGRVGDQQVVSPSW----------AHEPRQPVNHGE-VLDYRD 331 L+ T RD+ R G L+ G + ++++ W +H + GE L Y Sbjct: 285 LSATLRDYGRFGQFVLEDGVIDGERILPEGWVDRASRVEASSHLAPGKLYDGEYALGYGY 344 Query: 332 GWWIPPGNA------DDRDFSAIGVFGQYIYVNPATRTVIVKLSDY 371 WW P A D F A G+FGQY+Y+N + V V S + Sbjct: 345 QWWTFPVGAKALPEHDGGAFEAQGIFGQYLYINRKEKIVAVVWSAW 390 >PA4347 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Pae Pseudomonas aeruginosa Length = 384 Score = 119 bits (299), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 93/295 (31%), Positives = 146/295 (49%), Gaps = 28/295 (9%) Query: 96 KTTSAHAFVVIQDGKIVYERYIDGYDANSRFTSFSVAKSFVSALTGVALQQGKIRSLDEP 155 K A VVI+DG++VYERY A + ++SV+KS ++ L GVA +G+ + LD+P Sbjct: 73 KGIRTDAVVVIRDGRLVYERYAGPSRAETPHLTWSVSKSLLATLLGVAEGEGRFQ-LDDP 131 Query: 156 IGHYLNSDEIAPAYAGITIGQLLDMRSGIDVDENYG-GSLASPVVRMFVST---DLHRFI 211 + Y P +T+ LL+ SG+D E+Y L S VV M + D+ F+ Sbjct: 132 VARYYPPFARHPE---VTLRHLLNWSSGLDWQEDYEFAPLKSSVVAMLYTRGRDDMAGFV 188 Query: 212 ARRSGLRFAPGSRFEYRSVDTLVLSRVLAHATGMRLSDFAQQVLWEPLGMEQDASWSVDS 271 A R PG RF Y S D+ VL+ L G +++ + L+EPLG+ + A W D+ Sbjct: 189 AETPQAR-PPGRRFRYSSGDSNVLAAALHGMLGADYAEYPWRALFEPLGI-RSAVWERDA 246 Query: 272 GQHGVEKAFCCLNTTARDFARLGLLYLDGGRVGDQQVVSPSWAHEPRQPVNHGEVLDYRD 331 V ++ + +ARD AR+GLL GR ++Q++ +W P + Sbjct: 247 AGTFVGSSYVYM--SARDLARVGLLMQRHGRWRERQLLPLAWVEFNLTPFARYRPSAEEE 304 Query: 332 G-------WWI---------PPGNADDRDFSAIGVFGQYIYVNPATRTVIVKLSD 370 G WW+ P + + F+A+G +GQ +YV P + VIV+ +D Sbjct: 305 GEAVPGGQWWLNRAVKGAPAPWPDVAETAFAALGHWGQALYVLPEEKLVIVRYAD 359 >Rv1723 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Mtu Mycobacterium tuberculosis H37Rv Length = 415 Score = 117 bits (292), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 108/350 (30%), Positives = 156/350 (44%), Gaps = 45/350 (12%) Query: 78 EISVPWKDGSQLPVIDFLKTTSAHAFVVIQDGKIVYERYIDGYDANSRFTSFSVAKSFVS 137 +I + DG V + T+ + V G +V E+Y+DG +R FSV+KS V+ Sbjct: 55 DIGLTSTDGIATTVGAVMAATATDGWAVAHRGALVAEQYLDGLGPRTRHLLFSVSKSLVA 114 Query: 138 ALTGVALQQGKIRSLDEPIGHYLNSDEIAPAYAGITIGQLLDMRSGIDVDENYGGSLASP 197 A+ G G I LD P+ Y+ + YAG T+ LLDMRSG+ ENY A Sbjct: 115 AVVGALHGAGAIE-LDAPVTAYVPALADC-GYAGATVRHLLDMRSGVAFSENYDDPAAEI 172 Query: 198 VVRMFV-------STDL------HRFIARRSGLRFAPGSRFEYRSVDTLVLSRVLAHATG 244 VR V DL + RR + A G FEYRS +T VL + A G Sbjct: 173 HVREQVIGWAPKRGPDLPATLRDYLLTLRR---KSAHGGPFEYRSCETDVLGWICEAAAG 229 Query: 245 MRLSDFAQQVLWEPLGMEQDASWSVD-SGQHGVEKAFCCLNTTARDFARLGLLYL-DGGR 302 + + ++LW +G + DA+ ++D +G G ++ D R G LYL DG Sbjct: 230 QPMPELMSELLWSRIGAQCDATIALDVAGAAGTGIFDGGISACLTDMIRFGSLYLRDGVS 289 Query: 303 VGDQQVVSPSW----------------AHEPRQPVNHGEVLDYRDGWWIP-PGNADDRDF 345 + QQVV +W A P+ G YR+ W P PG+ Sbjct: 290 LAGQQVVPAAWIADTFDGGPDSRQAFAASPDDNPMPGGM---YRNQVWFPYPGS---NVA 343 Query: 346 SAIGVFGQYIYVNPATRTVIVKLSD--YGVEQDEVLTMLAMRSISHYVAG 393 +G+ GQ IYVN A V KLS + E + T+ A +++H ++G Sbjct: 344 LCVGMCGQLIYVNRAAEVVAAKLSTQPHSHEPHMLDTLRAFDAVAHELSG 393 >MT1764 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins MtC Mycobacterium tuberculosis CDC1551 Length = 415 Score = 117 bits (292), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 108/350 (30%), Positives = 156/350 (44%), Gaps = 45/350 (12%) Query: 78 EISVPWKDGSQLPVIDFLKTTSAHAFVVIQDGKIVYERYIDGYDANSRFTSFSVAKSFVS 137 +I + DG V + T+ + V G +V E+Y+DG +R FSV+KS V+ Sbjct: 55 DIGLTSTDGIATTVGAVMAATATDGWAVAHRGALVAEQYLDGLGPRTRHLLFSVSKSLVA 114 Query: 138 ALTGVALQQGKIRSLDEPIGHYLNSDEIAPAYAGITIGQLLDMRSGIDVDENYGGSLASP 197 A+ G G I LD P+ Y+ + YAG T+ LLDMRSG+ ENY A Sbjct: 115 AVVGALHGAGAIE-LDAPVTAYVPALADC-GYAGATVRHLLDMRSGVAFSENYDDPAAEI 172 Query: 198 VVRMFV-------STDL------HRFIARRSGLRFAPGSRFEYRSVDTLVLSRVLAHATG 244 VR V DL + RR + A G FEYRS +T VL + A G Sbjct: 173 HVREQVIGWAPKRGPDLPATLRDYLLTLRR---KSAHGGPFEYRSCETDVLGWICEAAAG 229 Query: 245 MRLSDFAQQVLWEPLGMEQDASWSVD-SGQHGVEKAFCCLNTTARDFARLGLLYL-DGGR 302 + + ++LW +G + DA+ ++D +G G ++ D R G LYL DG Sbjct: 230 QPMPELMSELLWSRIGAQCDATIALDVAGAAGTGIFDGGISACLTDMIRFGSLYLRDGVS 289 Query: 303 VGDQQVVSPSW----------------AHEPRQPVNHGEVLDYRDGWWIP-PGNADDRDF 345 + QQVV +W A P+ G YR+ W P PG+ Sbjct: 290 LAGQQVVPAAWIADTFDGGPDSRQAFAASPDDNPMPGGM---YRNQVWFPYPGS---NVA 343 Query: 346 SAIGVFGQYIYVNPATRTVIVKLSD--YGVEQDEVLTMLAMRSISHYVAG 393 +G+ GQ IYVN A V KLS + E + T+ A +++H ++G Sbjct: 344 LCVGMCGQLIYVNRAAEVVAAKLSTQPHSHEPHMLDTLRAFDAVAHELSG 393 >mll2884 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Mlo Mesorhizobium loti Length = 385 Score = 116 bits (290), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 95/312 (30%), Positives = 146/312 (46%), Gaps = 38/312 (12%) Query: 85 DGSQLPVIDFLKTTSAHAFVVIQDGKIVYERYIDGYDANSRFTSFSVAKSFVSALTGVAL 144 +G + L T F+V++ GK+ YERY +G D + S S+AKS ++ G+ Sbjct: 63 EGKPSTLAGLLDETYTDGFLVLKHGKVAYERYFNGMDERTLHLSQSMAKSITGSVFGILA 122 Query: 145 QQGKIRSLDEPIGHYLNSDEIAPAYAGITIGQLLDMRSGIDVDENYGGSLASPVVRMFVS 204 +G I P+ YL + A +AG ++ +LDM +G+ E Y S + ++ V+ Sbjct: 123 GRGLIDPA-RPVTDYL-PELGATGWAGASVQHVLDMTTGVRFSEEYTDRY-SDIGQVDVA 179 Query: 205 TDL---------------HRF---IARRSGLRFAPGSRFEYRSVDTLVLSRVLAHATGMR 246 T H F + + +R G+ FEYRS++T VL+ ++ TG R Sbjct: 180 TGWKPVPPGSDPDFRWPSHMFELILGLKDTVR-PHGAAFEYRSIETDVLAFIMERVTGKR 238 Query: 247 LSDFAQQVLWEPLGMEQDASWSVDSGQHGVEKAFCCLNTTARDFARLGLLYLDGGRVGDQ 306 L+ + LW+ LG ++ A ++VDS + V A N T RD+ R G L LD G Sbjct: 239 LAQLVSEELWQKLGADESACFTVDSAGYAV--ADGGFNATLRDYGRFGQLILDNG----G 292 Query: 307 QVVSPSWAHEPRQPVNHGEVL-------DYRDGWWIPPGNADDRDFSAIGVFGQYIYVNP 359 +V W R HG YR+ +WI N R GVFGQ I+++ Sbjct: 293 GIVPADWIEATRNG-RHGPDFSPSLPEGSYRNQFWIE--NPRSRALMCRGVFGQMIHIDW 349 Query: 360 ATRTVIVKLSDY 371 T V+VKLS + Sbjct: 350 NTGMVVVKLSTW 361 >RSc1765 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Rso Ralstonia solanacearum Length = 397 Score = 109 bits (273), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 89/335 (26%), Positives = 153/335 (45%), Gaps = 38/335 (11%) Query: 85 DGSQLPVIDFLKTTSAHAFVVIQDGKIVYERYIDGYDANSRFTSFSVAKSFVSALTGVAL 144 DG + D L T +V+ G++VYERY DA++ + SV +SFV L + Sbjct: 69 DGRRRTFADMLALTYTDGILVMHRGQVVYERYFGALDAHTPHIAMSVTQSFVGTLAAMLA 128 Query: 145 QQGKIRSLDEPIGHYLNSDEIAPAYAGITIGQLLDMRSGIDVDEN-------------YG 191 G++ P+ Y+ + + AY T+ Q++DM G+ EN G Sbjct: 129 ADGRLDPA-APVTQYVPELKDS-AYGDATVRQVMDMTVGVRYSENDADPDADVWRYARAG 186 Query: 192 GSLASPVVRMFVSTDLHRFIA--RRSGLRFAPGSRFEYRSVDTLVLSRVLAHATGMRLSD 249 G L P +L+ ++ R+ G G+ F ++V+ VL+ ++ A+G LS Sbjct: 187 GMLPRPAGDS-GPANLYDYLKTLRKEGEH---GAAFADKTVNAEVLAWIVRRASGQSLSA 242 Query: 250 FAQQVLWEPLGMEQDASWSVDSGQHGVEKAFCCLNTTARDFARLGLLYLDGGRVGDQQVV 309 +W+P+G + DA +++DS G E LNTT D AR + + GR +Q++ Sbjct: 243 LLSARIWQPMGAQGDAYFTLDS--IGTESGGGGLNTTLADLARFAEMLRNDGRFNGRQIL 300 Query: 310 SPSWAHEPRQ---PVNHGEV-------LDYRDGWWIPPGNADDRDFSAIGVFGQYIYVNP 359 + + R+ P YRD WW+ D F A G+ GQ IY++P Sbjct: 301 PRAVIDDIRRGGDPARFARAGYATLPGYSYRDMWWV--SGDDHHTFEARGIHGQRIYIDP 358 Query: 360 ATRTVIVKLSDYGVEQDEV---LTMLAMRSISHYV 391 + IV+ + + + + V +T A R+++ ++ Sbjct: 359 VAQMTIVRYASHPIAANAVNDPVTHRAYRALADFL 393 >mll2882 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Mlo Mesorhizobium loti Length = 393 Score = 105 bits (262), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 87/312 (27%), Positives = 136/312 (43%), Gaps = 32/312 (10%) Query: 91 VIDFLKTTSAHAFVVIQDGKIVYERYIDGYDANSRFTSFSVAKSFVSALTGVALQQGKIR 150 V +FL + A V++ GK++ + + D +R FS++KS V+A+ L+ + Sbjct: 76 VAEFLIRSRTDALTVMKGGKVIGDWFAPHMDFGARHIIFSISKS-VTAIVAGTLEGEGVF 134 Query: 151 SLDEPIGHYLNSDEIAPAYAGITIGQLLDMRSGIDVDENYGGSLASPVVRMFVST----- 205 + P+ Y+ + AY + +LDM +D +E Y S R +T Sbjct: 135 DPEAPVTTYI-PEAAGSAYGDASCRHVLDMSVSLDFEEAYLDP-ESAFARYRRATLWNPG 192 Query: 206 ----DLHRFIARRSGLRFAPGSRFEYRSVDTLVLSRVLAHATGMRLSDFAQQVLWEPLGM 261 L FI L G F YRS ++ +L +L A+G R SD ++ LW PLG Sbjct: 193 GGTESLREFILSLQRLAEPHGQTFRYRSPNSDLLGLLLERASGQRFSDLMREKLWLPLGA 252 Query: 262 EQDASWSVDSGQHGVEKAFCCLNTTARDFARLGLLYLDGGRVGDQQVVSPSWAHEPRQPV 321 DAS VD G + ++ T RD AR+G + GG +++V +W + Sbjct: 253 VSDASIGVD--MEGTARTAGGISVTPRDLARVGEMMRQGGTANGRRIVPEAWVRDTVSTG 310 Query: 322 NHGEVLD------------YRDGWWI--PPGNADDRDFSAIGVFGQYIYVNPATRTVIVK 367 E YRD W+ P A + IG+ GQ++YV+P VI K Sbjct: 311 GSAEAWHRGTMAFLFPHGRYRDKWYQTGKPSGA----YCGIGIHGQWLYVDPKAEVVIAK 366 Query: 368 LSDYGVEQDEVL 379 +S V D+ L Sbjct: 367 MSSQPVPVDDPL 378 >AGc1692 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 451 Score = 100 bits (250), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 93/330 (28%), Positives = 149/330 (45%), Gaps = 35/330 (10%) Query: 92 IDFLKTTSAH---AFVVIQDGKIVYERYIDGYDANSRFTSFSVAKSFVSALTGVALQQGK 148 + +L++ SA+ VV+ G +VYERY + + + SV KS L + + +G Sbjct: 124 MTWLQSLSANYTDGIVVLHKGVLVYERYSGCLNEAGQHGAMSVTKSLTGLLGEMLVAEG- 182 Query: 149 IRSLDEPIGHYLNSDEI-APAYAGITIGQLLDMRSGIDVDENYGGSLASPVVRMFVSTDL 207 +LDE E+ A+ TI Q+LDM +G+ E+Y A + L Sbjct: 183 --TLDENAKVATVVPELEKSAFGDATIRQVLDMTTGLRYSEDYADPNADVWIYSAAGNPL 240 Query: 208 HR---FIARRSGLRFAP--------GSRFEYRSVDTLVLSRVLAHATGMRLSDFAQQVLW 256 + + RS + GS F Y+++++ L V+A A+G +++ Q +W Sbjct: 241 PKPDGYEGPRSYFDYLKTVVKQGENGSAFGYKTINSDALGWVIARASGKSVAELLSQRIW 300 Query: 257 EPLGMEQDASWSVDSGQHGVEKAFCCLNTTARDFARLGLLYLDGGRVGDQQVVSPSWAHE 316 +G EQDA ++VDS G A LN RD AR+G L LD G G +++ Sbjct: 301 SRIGAEQDAYYTVDS--TGTPFAGGGLNAGLRDMARIGQLLLDDGMAGGHRLIPQKAIDN 358 Query: 317 PRQPVNHGEVL----------DYRDGWWIPPGNADDRDFSAIGVFGQYIYVNPATRTVIV 366 R + YR WW+ NA+ F A GV GQ IYV+PA VI Sbjct: 359 IRHGGDKAAFAKGGYPALRGWSYRAMWWV-THNANGA-FMARGVHGQAIYVDPAADMVIA 416 Query: 367 KLSDYGVEQ---DEVLTMLAMRSISHYVAG 393 + S + V ++ ++ A +++ Y+ G Sbjct: 417 RFSSHPVASNAANDPTSLPAYEAVARYLMG 446 >BMEII0318 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Bme Brucella melitensis Length = 256 Score = 90.5 bits (223), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 68/211 (32%), Positives = 107/211 (50%), Gaps = 18/211 (8%) Query: 53 YKVFEANRIARSTHPRPWPMALRALEISVPWKDGSQLPVIDFLKTTSAHAFVVIQDGKIV 112 YK + + R+ + P P + L + +K G V D+L+ T F+V++DG +V Sbjct: 56 YKKYPSVRVPHTGEVSPLPRGEQPLPETYTYK-GETRKVADWLERTDTTGFIVLKDGVVV 114 Query: 113 YERYIDGYDANSRFTSFSVAKSFVSALTGVALQQGKIRSLDEPIGHYLNSDEIAP----- 167 +E+Y G ++ + S++KSFVS L G A++ G+I+ LD+ + HY AP Sbjct: 115 HEQYERGNSETTQSIAMSLSKSFVSFLVGNAVRDGQIK-LDQTVDHY------APLLKEG 167 Query: 168 AYAGITIGQLLDMRSGIDVDENYGGSLASPVVRMFV---STDLHRFIARRSGLRFAPGSR 224 Y +T+ +L M SGI +ENY G L S +VR V + + F A+ G+ Sbjct: 168 GYKEVTVKNVLQMSSGIGFNENY-GDLNSDIVRYIVQMLTGSVDDFTAKLKN-EVPQGTI 225 Query: 225 FEYRSVDTLVLSRVLAHATGMRLSDFAQQVL 255 Y S DT VL+ VL ATG+ + + L Sbjct: 226 NHYVSADTQVLAMVLEGATGVPFQKYFEDKL 256